Mr Imam Fathoni
Technical Officer
Office of Sciences
College of Sciences
Dr Imam (Toni) Fathoni is a Technical Officer in the Malaria and Toxoplasma Laboratory at the School of Biological Sciences, Adelaide University. He is working on developing a research model for Cryptosporidium, a parasite that causes gastrointestinal infections. Toni completed his PhD at the Australian National University under the supervision of Kevin Saliba, where he investigated thiamine (vitamin B1) metabolism as a potential drug target against malaria parasites, Plasmodium. He also completed a one-year research exchange at Humboldt University Berlin under the supervision of Kai Matuschewski. He has expertise in both in vitro and in vivo models of malaria parasites. Before moving to Adelaide, he worked as a laboratory officer at Diversity Arrays Technology, where he was part of the Research and Development department, developing a high-throughput method for soil DNA extraction to investigate microbial biodiversity in soil.
| Date | Position | Institution name |
|---|---|---|
| 2025 - ongoing | Technical Officer | Adelaide University |
| 2023 - 2025 | Laboratory Officer | Diversity Arrays Technology (DArT) |
| 2020 - 2022 | Technical Assistant | Australian National University |
| Language | Competency |
|---|---|
| English | Can read, write, speak, understand spoken and peer review |
| Date | Institution name | Country | Title |
|---|---|---|---|
| 2022 - 2023 | Humboldt-Universität zu Berlin | Germany | PhD (research exchange) |
| 2020 - 2025 | Australian National University | Australia | PhD |
| Year | Citation |
|---|---|
| 2024 | Fathoni, I., Ho, T. C. S., Chan, A. H. Y., Leeper, F. J., Matuschewski, K., & Saliba, K. J. (2024). Identification and characterization of thiamine analogs with antiplasmodial activity. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 68(12), 15 pages. WoS3 Europe PMC3 |
| 2024 | Redway, A., Spry, C., Brown, A., Wiedemann, U., Fathoni, I., Garnie, L. F., . . . Downer-Riley, N. (2024). Discovery of antiplasmodial pyridine carboxamides and thiocarboxamides. International Journal for Parasitology Drugs and Drug Resistance, 25, 100536. Scopus4 Europe PMC1 |
| 2023 | Chan, A. H. Y., Ho, T. C. S., Fathoni, I., Pope, R., Saliba, K. J., & Leeper, F. J. (2023). Inhibition of Thiamine Diphosphate-Dependent Enzymes by Triazole-Based Thiamine Analogues. ACS Medicinal Chemistry Letters, 14(5), 621-628. Scopus12 WoS14 Europe PMC12 |
| 2023 | El Bakali, J., Blaszczyk, M., Evans, J. C., Boland, J. A., McCarthy, W. J., Fathoni, I., . . . Spry, C. (2023). Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference. Angewandte Chemie International Edition, 62(17), e202300221-1-e202300221-8. Scopus7 WoS6 Europe PMC8 |
| 2022 | Chan, A. H. Y., Fathoni, I., Ho, T. C. S., Saliba, K. J., & Leeper, F. J. (2022). Thiamine analogues as inhibitors of pyruvate dehydrogenase and discovery of a thiamine analogue with non-thiamine related antiplasmodial activity. RSC MEDICINAL CHEMISTRY, 13(7), 817-821. WoS16 Europe PMC16 |
| 2020 | Fathoni, I., Petitbois, J. G., Alarif, W. M., Abdel-Lateff, A., Al-Lihaibi, S. S., Yoshimura, E., . . . Okino, T. (2020). Bioactivities of Lyngbyabellins from Cyanobacteria of <i>Moorea</i> and <i>Okeania</i> Genera. MOLECULES, 25(17), 9 pages. WoS15 Europe PMC8 |
| - | Chan, A. H. Y., Ho, T. C. S., Fathoni, I., Hamid, R., Hirsch, A. K. H., Saliba, K. J., & Leeper, F. J. (2024). Evaluation of ketoclomazone and its analogues as inhibitors of 1-deoxy-<scp>d</scp>-xylulose 5-phosphate synthases and other thiamine diphosphate (ThDP)-dependent enzymes. RSC Medicinal Chemistry, 15(5), 1773-1781. |
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