Beatriz Jimenez Garrido

Dr Beatriz Jimenez Garrido

Senior Lecturer

School of Physics, Chemistry and Earth Sciences

Faculty of Sciences, Engineering and Technology


Year Citation
2025 Antcliffe, D. B., Harte, E., Hussain, H., Jiménez, B., Browning, C., & Gordon, A. C. (2025). Metabolic septic shock sub-phenotypes, stability over time and association with clinical outcome. Intensive Care Medicine, 51(3), 529-541.
DOI Scopus4 WoS6 Europe PMC3
2025 Yan, Y., Jiménez, B., Judge, M. T., Athersuch, T., De Iorio, M., & Ebbels, T. M. D. (2025). MetAssimulo 2.0: a web app for simulating realistic 1D and 2D metabolomic 1H NMR spectra. Bioinformatics, 41(3), 5 pages.
DOI
2025 Xu, K., Hernández, B., Arpawong, T. E., Camuzeaux, S., Chekmeneva, E., Crimmins, E. M., . . . Robinson, O. (2025). Assessing Metabolic Ageing via <scp>DNA</scp> Methylation Surrogate Markers: A Multicohort Study in Britain, Ireland and the <scp>USA</scp>. Aging Cell, 24(5), 15 pages.
DOI Scopus2 WoS1 Europe PMC1
2024 Yan, Y., Judge, M. T., Athersuch, T., Xiang, Y., Liu, Z., Jiménez, B., & Ebbels, T. M. D. (2024). Resolution Enhancement of Metabolomic J-Res NMR Spectra Using Deep Learning. Analytical Chemistry, 96(29), 11707-11715.
DOI Scopus9 WoS8 Europe PMC4
2024 Trainor, N., Whitwell, H. J., Jiménez, B., Addison, K., Leonidou, E., DiMaggio, P. A., & Fuchter, M. J. (2024). Tracking DOT1L methyltransferase activity by stable isotope labelling using a selective synthetic co-factor. Communications Chemistry, 7(1), 7 pages.
DOI Scopus2 WoS2 Europe PMC1
2024 Alexander, J. L., Wyatt, N. J., Camuzeaux, S., Chekmeneva, E., Jimenez, B., Sands, C. J., . . . Lamb, C. A. (2024). Considerations for peripheral blood transport and storage during large-scale multicentre metabolome research. Gut, 73(2), 379.1-383.
DOI Scopus3 WoS3 Europe PMC3
2023 Garcia‐Segura, M. E., Durainayagam, B. R., Liggi, S., Graça, G., Jimenez, B., Dehghan, A., . . . Griffin, J. L. (2023). Pathway‐based integration of multi‐omics data reveals lipidomics alterations validated in an Alzheimer's disease mouse model and risk loci carriers. Journal of Neurochemistry, 164(1), 57-76.
DOI Scopus13 WoS13 Europe PMC17
2023 Harvey, N., Takis, P. G., Lindon, J. C., Li, J. V., & Jiménez, B. (2023). Optimization of Diffusion-Ordered NMR Spectroscopy Experiments for High-Throughput Automation in Human Metabolic Phenotyping. Analytical Chemistry, 95(6), 3147-3152.
DOI Scopus6 WoS4 Europe PMC4
2022 Hussain, H., Vutipongsatorn, K., Jiménez, B., & Antcliffe, D. B. (2022). Patient Stratification in Sepsis: Using Metabolomics to Detect Clinical Phenotypes, Sub-Phenotypes and Therapeutic Response. Metabolites, 12(5), 42 pages.
DOI Scopus28 WoS25 Europe PMC25
2022 Sliz, E., Shin, J., Ahmad, S., Williams, D. M., Frenzel, S., Gauß, F., . . . Pausova, Z. (2022). Circulating Metabolome and White Matter Hyperintensities in Women and Men. Circulation, 145(14), 1040-1052.
DOI Scopus26 WoS26 Europe PMC28
2022 Albreht, A., Hussain, H., Jiménez, B., Yuen, A. H. Y., Whiley, L., Witt, M., . . . Chekmeneva, E. (2022). Structure Elucidation and Mitigation of Endogenous Interferences in LC-MS-Based Metabolic Profiling of Urine. Analytical Chemistry, 94(3), 1760-1768.
DOI Scopus9 WoS7 Europe PMC8
2021 Takis, P. G., Jiménez, B., Al-Saffar, N. M. S., Harvey, N., Chekmeneva, E., Misra, S., & Lewis, M. R. (2021). A Computationally Lightweight Algorithm for Deriving Reliable Metabolite Panel Measurements from 1D <sup>1</sup>H NMR. Analytical Chemistry, 93(12), 4995-5000.
DOI Scopus6 WoS5 Europe PMC5
2021 Whiley, L., Chappell, K. E., D’Hondt, E., Lewis, M. R., Jiménez, B., Snowden, S. G., . . . Holmes, E. (2021). Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with Alzheimer’s disease. Alzheimer's Research &amp; Therapy, 13(1), 18 pages.
DOI Scopus96 WoS87 Europe PMC80
2021 Jiménez, B., Abellona U, M. R., Drymousis, P., Kyriakides, M., Clift, A. K., Liu, D. S. K., . . . Frilling, A. (2021). Neuroendocrine Neoplasms: Identification of Novel Metabolic Circuits of Potential Diagnostic Utility. Cancers, 13(3), 374.
DOI Scopus4 WoS4 Europe PMC4
2020 Andreas, N. J., Basu Roy, R., Gomez-Romero, M., Horneffer-van der Sluis, V., Lewis, M. R., Camuzeaux, S. S. M., . . . Kampmann, B. (2020). Performance of metabonomic serum analysis for diagnostics in paediatric tuberculosis. Scientific Reports, 10(1), 11 pages.
DOI Scopus12 WoS11 Europe PMC13
2020 Kurbatova, N., Garg, M., Whiley, L., Chekmeneva, E., Jiménez, B., Gómez-Romero, M., . . . Lovestone, S. (2020). Urinary metabolic phenotyping for Alzheimer’s disease. Scientific Reports, 10(1), 17 pages.
DOI Scopus35 WoS30 Europe PMC30
2020 Takis, P. G., Jiménez, B., Sands, C. J., Chekmeneva, E., & Lewis, M. R. (2020). SMolESY: an efficient and quantitative alternative to on-instrument macromolecular <sup>1</sup>H-NMR signal suppression. Chemical Science, 11(23), 6000-6011.
DOI Scopus21 WoS20 Europe PMC19
2019 Rodriguez-Martinez, A., Ayala, R., Posma, J. M., Harvey, N., Jiménez, B., Sonomura, K., . . . Dumas, M. E. (2019). PJRES Binning Algorithm (JBA): A new method to facilitate the recovery of metabolic information from pJRES 1H NMR spectra. Bioinformatics, 35(11), 1916-1922.
DOI Scopus12 WoS10 Europe PMC11
2019 Harbaum, L., Ghataorhe, P., Wharton, J., Jiménez, B., Howard, L. S. G., Gibbs, J. S. R., . . . Wilkins, M. R. (2019). Reduced plasma levels of small HDL particles transporting fibrinolytic proteins in pulmonary arterial hypertension. Thorax, 74(4), 380-389.
DOI Scopus41 WoS34 Europe PMC33
2019 Whiley, L., Chekmeneva, E., Berry, D. J., Jiménez, B., Yuen, A. H. Y., Salam, A., . . . Lewis, M. R. (2019). Systematic Isolation and Structure Elucidation of Urinary Metabolites Optimized for the Analytical-Scale Molecular Profiling Laboratory. Analytical Chemistry, 91(14), 8873-8882.
DOI Scopus12 WoS12 Europe PMC11
2019 Sands, C. J., Wolfer, A. M., Correia, G. D. S., Sadawi, N., Ahmed, A., Jiménez, B., . . . Pearce, J. T. M. (2019). The nPYc-Toolbox, a Python module for the pre-processing, quality-control and analysis of metabolic profiling datasets. Bioinformatics, 35(24), 5359-5360.
DOI Scopus30 WoS31 Europe PMC32
2018 Jiménez, B., Holmes, E., Heude, C., Tolson, R. F., Harvey, N., Lodge, S. L., . . . Nicholson, J. K. (2018). Quantitative Lipoprotein Subclass and Low Molecular Weight Metabolite Analysis in Human Serum and Plasma by 1H NMR Spectroscopy in a Multilaboratory Trial. Analytical Chemistry, 90(20), 11962-11971.
DOI Scopus193 WoS184 Europe PMC177
2018 Gafson, A. R., Thorne, T., McKechnie, C. I. J., Jimenez, B., Nicholas, R., & Matthews, P. M. (2018). Lipoprotein markers associated with disability from multiple sclerosis. Scientific Reports, 8(1), 8 pages.
DOI Scopus29 WoS29 Europe PMC27
2017 Rodriguez-Martinez, A., Posma, J. M., Ayala, R., Harvey, N., Jimenez, B., Neves, A. L., . . . Dumas, M. E. (2017). J-Resolved 1H NMR 1D-Projections for Large-Scale Metabolic Phenotyping Studies: Application to Blood Plasma Analysis. Analytical Chemistry, 89(21), 11405-11412.
DOI Scopus19 WoS19 Europe PMC17
2017 Antcliffe, D., Jiménez, B., Veselkov, K., Holmes, E., & Gordon, A. C. (2017). Metabolic Profiling in Patients with Pneumonia on Intensive Care. Ebiomedicine, 18, 244-253.
DOI Scopus21 WoS20 Europe PMC17
2017 Ferrario, C., Statello, R., Carnevali, L., Mancabelli, L., Milani, C., Mangifesta, M., . . . Turroni, F. (2017). How to feed the Mammalian gut microbiota: Bacterial and metabolic modulation by dietary fibers. Frontiers in Microbiology, 8(SEP), 11 pages.
DOI Scopus77 WoS75 Europe PMC64
2017 Bray, R., Cacciatore, S., Jiménez, B., Cartwright, R., Digesu, A., Fernando, R., . . . Khullar, V. (2017). Urinary Metabolic Phenotyping of Women with Lower Urinary Tract Symptoms. Journal of Proteome Research, 16(11), 4208-4216.
DOI Scopus12 WoS11 Europe PMC10
2016 Scientific Abstracts (2016). Reproductive Sciences, 23(1_suppl), 51A-344A.
DOI
2015 Jiménez, B. (2015). NMR-based metabolic phenotyping for disease diagnosis and stratification. Emagres, 4(2), 269-276.
DOI
2015 Correia, G. D. S., Wooi Ng, K., Wijeyesekera, A., Gala-Peralta, S., Williams, R., Maccarthy-Morrogh, S., . . . Pathan, N. (2015). Metabolic profiling of children undergoing surgery for congenital heart disease. Critical Care Medicine, 43(7), 1467-1476.
DOI Scopus46 WoS41 Europe PMC37
2015 Powles, S. T. R., Hicks, L. C., Jimenez, B., Merrifield, C., Holmes, E., Williams, H. R. T., & Orchard, T. R. (2015). EFFECT OF CO-MORBIDITIES ON URINARY METABOLIC PROFILING IN THE CHARACTERISATION OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE. GUT, 64(Suppl 1), A436-A437.
DOI
2014 Mirnezami, R., Jiménez, B., Li, J. V., Kinross, J. M., Veselkov, K., Goldin, R. D., . . . Darzi, A. (2014). Rapid diagnosis and staging of colorectal cancer via high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy of intact tissue biopsies. Annals of Surgery, 259(6), 1138-1149.
DOI Scopus71 WoS62 Europe PMC55
2014 Dona, A. C., Jiménez, B., Schafer, H., Humpfer, E., Spraul, M., Lewis, M. R., . . . Nicholson, J. K. (2014). Precision high-throughput proton NMR spectroscopy of human urine, serum, and plasma for large-scale metabolic phenotyping. Analytical Chemistry, 86(19), 9887-9894.
DOI Scopus435 WoS408 Europe PMC362
2013 Jiménez, B., Mirnezami, R., Kinross, J., Cloarec, O., Keun, H. C., Holmes, E., . . . Nicholson, J. K. (2013). 1H HR-MAS NMR spectroscopy of tumor-induced local metabolic "field-effects" enables colorectal cancer staging and prognostication. Journal of Proteome Research, 12(2), 959-968.
DOI Scopus112 WoS97 Europe PMC86
2013 Kinross, J. M., Drymousis, P., Jiménez, B., & Frilling, A. (2013). Metabonomic profiling: A novel approach in neuroendocrine neoplasias. Surgery United States, 154(6), 1185-1193.
DOI Scopus27 WoS27 Europe PMC22
2012 Wong, A., Jiménez, B., Li, X., Holmes, E., Nicholson, J. K., Lindon, J. C., & Sakellariou, D. (2012). Evaluation of high resolution magic-angle coil spinning NMR spectroscopy for metabolic profiling of nanoliter tissue biopsies. Analytical Chemistry, 84(8), 3843-3848.
DOI Scopus40 WoS37 Europe PMC27
2012 Gómez-Mingot, M., Alcaraz, L. A., MacIntyre, D. A., Jiménez, B., Pineda-Lucena, A., Montiel, V., . . . Iniesta, J. (2012). Development of a novel analytical approach combining the quantification of amino acids, organic acids and glucose using HPLC-UV-Vis and HPLC-MS with screening via NMR. Analytical Methods, 4(1), 284-290.
DOI Scopus8 WoS7
2012 Jiménez, B., Ugwu, F., Zhao, R., Ortí, L., Makhnevych, T., Pineda-Lucena, A., & Houry, W. A. (2012). Structure of minimal tetratricopeptide repeat domain protein Tah1 reveals mechanism of its interaction with Pih1 and Hsp90. Journal of Biological Chemistry, 287(8), 5698-5709.
DOI Scopus43 WoS41 Europe PMC42
2011 MacIntyre, D. A., Sanchís, D. M., Jiménez, B., Moreno, R., Stojkovic, M., & Pineda-Lucena, A. (2011). Characterisation of human embryonic stem cells conditioning media by 1H-nuclear magnetic resonance spectroscopy. Plos One, 6(2), 11 pages.
DOI Scopus21 WoS18 Europe PMC17
2010 Jiménez, B., Montoliu, C., MacIntyre, D. A., Serra, M. A., Wassel, A., Jover, M., . . . Felipo, V. (2010). Serum metabolic signature of minimal hepatic encephalopathy by 1H-nuclear magnetic resonance. Journal of Proteome Research, 9(10), 5180-5187.
DOI Scopus62 WoS56 Europe PMC50
2010 MacIntyre, D. A., Jiménez, B., Lewintre, E. J., Martín, C. R., Schäfer, H., Ballesteros, C. G., . . . Pineda-Lucena, A. (2010). Serum metabolome analysis by 1H-NMR reveals differences between chronic lymphocytic leukaemia molecular subgroups. Leukemia, 24(4), 788-797.
DOI Scopus136 WoS127 Europe PMC98
2008 Mori, M., Jiménez, B., Piccioli, M., Battistoni, A., & Sette, M. (2008). The solution structure of the monomeric copper, zinc superoxide dismutase from Salmonella enterica: Structural insights to understand the evolution toward the dimeric structure. Biochemistry, 47(49), 12954-12963.
DOI Scopus17 WoS15 Europe PMC12
2008 Bertini, I., Jiménez, B., Pierattelli, R., Wedd, A. G., & Xiao, Z. (2008). Protonless 13C direct detection NMR: Characterization of the 37 kDa trimeric protein CutA1. Proteins Structure Function and Genetics, 70(4), 1196-1205.
DOI Scopus13 WoS13 Europe PMC8
2007 Jiménez, B., Mori, M., Battistoni, A., Sette, M., & Piccioli, M. (2007). NMR assignment of reduced form of copper, zinc superoxide dismutase from Salmonella enterica. Biomolecular NMR Assignments, 1(1), 65-67.
DOI Scopus3 WoS3 Europe PMC3
2006 Balayssac, S., Jiménez, B., & Piccioli, M. (2006). 13C direct detected COCO-TOCSY: A tool for sequence specific assignment and structure determination in protonless NMR experiments. Journal of Magnetic Resonance, 182(2), 325-329.
DOI Scopus7 WoS8 Europe PMC6
2006 Balayssac, S., Jiménez, B., & Piccioli, M. (2006). Assignment strategy for fast relaxing signals: Complete aminoacid identification in thulium substituted calbindin D9K. Journal of Biomolecular NMR, 34(2), 63-73.
DOI Scopus32 WoS31 Europe PMC21
2005 Alcaraz, L. A., Jiménez, B., Moratal, J. M., & Donaire, A. (2005). An NMR view of the unfolding process of rusticyanin: Structural elements that maintain the architecture of a β-barrel metalloprotein. Protein Science, 14(7), 1710-1722.
DOI Scopus11 WoS12 Europe PMC9
2005 Bertini, I., Jiménez, B., & Piccioli, M. (2005). 13C Direct detected experiments: Optimization for paramagnetic signals. Journal of Magnetic Resonance, 174(1), 125-132.
DOI Scopus42 WoS38 Europe PMC26
2005 Bertini, I., Jiménez, B., Piccioli, M., & Poggi, L. (2005). Asymmetry in13C-13C COSY spectra provides information on ligand geometry in paramagnetic proteins. Journal of the American Chemical Society, 127(35), 12216-12217.
DOI Scopus21 WoS20 Europe PMC11
2003 Jiménez, B., Piccioli, M., Moratal, J. M., & Donaire, A. (2003). Backbone dynamics of rusticyanin: The high hydrophobicity and rigidity of this blue copper protein is responsible for its thermodynamic properties. Biochemistry, 42(35), 10396-10405.
DOI Scopus26 WoS26 Europe PMC17
2003 Jiménez, B., Poggi, L., & Piccioli, M. (2003). Monitoring the Early Steps of Unfolding of Dicalcium and Mono-Ce 3+-Substituted Forms of P43M Calbindin D9k. Biochemistry, 42(44), 13066-13073.
DOI Scopus5 WoS7 Europe PMC4
2002 Donaire, A., Jiménez, B., Fernández, C. O., Pierattelli, R., Niizeki, T., Moratal, J. M., . . . Vila, A. J. (2002). Metal-ligand interplay in blue copper proteins studied by 1H NMR spectroscopy: Cu(II)-pseudoazurin and Cu(II)-rusticyanin. Journal of the American Chemical Society, 124(46), 13698-13708.
DOI Scopus56 WoS55 Europe PMC36
2001 Donaire, A., Jiménez, B., Moratal, J. M., Hall, J. F., & Hasnain, S. S. (2001). Electronic characterization of the oxidized state of the blue copper protein rusticyanin by 1H NMR: Is the axial methionine the dominant influence for the high redox potential?. Biochemistry, 40(3), 837-846.
DOI Scopus42 WoS42 Europe PMC29
2001 Bertini, I., Donaire, A., Jiménez, B., Luchinat, C., Parigi, G., Piccioli, M., & Poggi, L. (2001). Paramagnetism-based versus classical constraints: An analysis of the solution structure of Ca Ln calbindin D9k. Journal of Biomolecular NMR, 21(2), 85-98.
DOI Scopus100 WoS96 Europe PMC68
- doi:10.1021/bi034638
DOI

Year Citation
2017 Jiménez, B., & MacIntyre, D. (2017). NMR Metabolic Phenotyping in Clinical Studies. In Encyclopedia of Spectroscopy and Spectrometry (pp. 140-145). Elsevier.
DOI Scopus2
2004 Jiménez, B., Moratal, J. M., Piccioli, M., & Donaire, A. (2004). Mobility studies in proteins by <SUP>15</SUP>N nuclear magnetic resonance:: Rusticyanin as an example. In R. M. Kamp, J. J. Calvete, & T. CholiPapadopoulou (Eds.), Principles and Practice (pp. 15-33). SPRINGER-VERLAG BERLIN.
DOI WoS4

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