Yannan Yang

Dr Yannan Yang

Group Leader, Biomat & Immune Eng Lab (BIEL)

South Australian Immunogenomics Cancer Institute

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Dr Yannan Yang completed PhD (Biomedical Engineering) in Australian Institute of Bioengineering and Nanotechnology/University of Queensland in 2019 before taking a postdoctoral research follow position in the same institute. In 2023, he established his own research group (Biomaterials and Immune Engineering Laboratory - BIEL) in SAiGENCI in the University of Adelaide. He has developed innovative synthetic approaches for biomaterials and nanoparticles with controllable architecture and composition, and demonstrated the great potential of materials based cancer immunotherapy. Dr Yang's vision is to develop novel biomaterials-enabled vaccine technology for cancer immunotherapy and promote the clinic translation of the technology to significantly improve the treatment outcome of cancers with poor prognosis.

Dr Yannan Yang is the head of Biomaterials and Immune Engineering Laboratory (BIEL). BIEL aims to leverage state-of-the-art biomaterials and nanotechnology-based approaches to modulate immune system and create translational immunotherapy strategies with improved therapeutic efficacy and minimized adverse effects. Our laboratory is specifically interested in designing and fabricating biocompatible nanoparticles, hydrogels, scaffolds and cell/bacteria derived biomimetic materials with immunomodulatory activities and controlled drug release profile for engineering immunity. We stand at the materials-bio interface and investigate how biomaterials at different scales (nano, micro and bulk) can interact with bio-systems and tumour microenvironment, and how these interactions can be further controlled to benefit the outcome of immunotherapy that aims to prevent and treat cancer.

  • Journals
    Year Citation
    2026 Dai, Z., Wang, Q., Zhang, M., Shi, Y., Yang, Y., Song, H., . . . Yu, C. (2026). Tumor-activated nanocomplex reprograms cancer and macrophage metabolism in opposite directions to overcome immune suppression. Biomaterials, 326, 123655.
    DOI
    2025 Gong, Y., Zhang, H., Lu, M., Sun, J., Jia, Y., Yang, Y., . . . Ling, Y. (2025). Tuning the Fe-Gd nanoparticles co-functionalized mesoporous carbon from sphere to nanobowl for advanced bioapplications. Journal of Colloid and Interface Science, 679(Pt B), 412-421.
    DOI Scopus4 WoS5 Europe PMC1
    2025 Luo, D., Wu, T., Qiu, T., Li, J., Gong, Y., Weng, J., . . . Zhou, Y. (2025). Coordination-Dissociation Induced T<inf>1</inf>-Weighted Magnetic Resonance Imaging Responses in a spn-Type MOF for Potential Drug Release Monitoring. Advanced Functional Materials, 35(33).
    DOI
    2025 Wu, T., Chen, Y., Gong, Y., Lu, M., Yang, C., Yang, Y., . . . Zhou, Y. (2025). A PI3K Inhibitor with Low Cardiotoxicity and Its Synergistic Inhibitory Effect with Gilteritinib in Acute Myelogenous Leukemia (AML) Cells. Molecules, 30(11), 17 pages.
    DOI
    2025 Shi, Y., Hou, Y., Mabrouk, M. T., Yu, C., & Yang, Y. (2025). In Situ Vaccines in the Era of Cancer Immunotherapy: Conceptual Innovation and Clinical Translation. Advanced Science, 23 pages.
    DOI
    2025 Liu, X., Wang, W., Wu, T., Li, J., Gong, Y., Luo, D., . . . Yang, Y. (2025). Local Delivery of Molecular Hydrogen by Fluorinated Zeolitic Imidazole Framework Nanosheets Boosts Cancer Immunotherapy.. ACS Appl Mater Interfaces, 12 pages.
    DOI
    2025 Luo, J., Wang, Y., Dai, Z., Shi, Y., Wu, W., Qu, J., . . . Yang, Y. (2025). Passivation-Engineered Zinc Peroxide Nanoparticles as Th1-Biased Adjuvant for Antitumor Immunity.. Small, e05250.
    DOI
    2024 Zhang, Y., Yu, Y., Yang, Y., Wang, Y., & Yu, C. (2024). Engineered Silica Nanoparticles for Nucleic Acid Delivery. Small Methods, 8(3), 2300812-1-2300812-16.
    DOI Scopus6 WoS4 Europe PMC4
    2024 Yang, Y., Chen, S., Zhang, M., Shi, Y., Luo, J., Huang, Y., . . . Yu, C. (2024). Mesoporous nanoperforators as membranolytic agents via nano- and molecular-scale multi-patterning.. Nat Commun, 15(1), 1891.
    DOI Scopus2 WoS2 Europe PMC2
    2024 Zhang, M., Lu, M., Gong, Y., Yang, Y., Song, J., Li, J., . . . Zhou, Y. (2024). Tadpole-Like Carbon Nanotube with Fe Nanoparticle Encapsulated at the Head and Zn Single-Atom Anchored on the Body: One-Pot Carbonization for Tetramodal Synergistic Cancer Therapy. Small, 20(40), e2400587.
    DOI Scopus3 WoS3
    2024 Huang, Y., Zou, J., Huo, J., Zhang, M., & Yang, Y. (2024). Sulfate Radical Based In Situ Vaccine Boosts Systemic Antitumor Immunity via Concurrent Activation of Necroptosis and STING Pathway. Advanced Materials, 36(41), e2407914-1-e2407914-15.
    DOI Scopus12 WoS11 Europe PMC7
    2024 Zhang, Y., Yao, Y., Xie, F., Hu, W. L., Zou, Y., Zhao, Q., . . . Yu, C. (2024). Iron consumption strengthens anti-tumoral STING activation mediated by manganese-based nanoparticles. Nano Today, 58, 102446.
    DOI Scopus4 WoS4
    2024 Huo, J., Zou, J., Ma, H., Meng, G., Huang, Y., Yan, X., . . . Zhang, M. (2024). Astragaloside IV microfibers assembling into injectable 3D-scaffolds with intrinsic immunoactivity for enhanced tumor vaccine efficacy. Chemical Engineering Journal, 498, 155511-1-155511-13.
    DOI Scopus1 WoS1
    2024 Lu, W., Wang, W., Gong, Y., Li, J., Zhou, Y., & Yang, Y. (2024). A Noncationic Biocatalytic Nanobiohybrid Platform for Cytosolic Protein Delivery Through Controlled Perturbation of Intracellular Redox Homeostasis.. Small, 20(49), 2407676-1-2407676-12.
    DOI Scopus5 WoS4 Europe PMC4
    2024 Jin, Y., Hu, C., Xia, J., Xie, D., Ye, L., Ye, X., . . . Hu, Z. (2024). Bimetallic clusterzymes-loaded dendritic mesoporous silica particle regulate arthritis microenvironment via ROS scavenging and YAP1 stabilization. Bioactive Materials, 42, 613-627.
    DOI Scopus4 WoS3
    2024 Li, J., Wu, T., Wang, W., Gong, Y., Lu, M., Zhang, M., . . . Yang, Y. (2024). Hybrid nanoparticle-mediated simultaneous ROS scavenging and STING activation improve the antitumor immunity of in situ vaccines. Science Advances, 10(38), eadn3002-1-eadn3002-15.
    DOI Scopus8 WoS5 Europe PMC4
    2023 Zhang, M., Lu, M., Qiu, T., Wang, Q., Chen, Z., Deng, M., . . . Zhou, Y. (2023). Gelothermal Synthesis of Monodisperse MIL-88A Nanoparticles with Tunable Sizes and Metal Centers for Potential Bioapplications. Small, 19(34), e2301894.
    DOI Scopus23 Europe PMC4
    2023 Zhang, M., Huang, Y., Zou, J., Yang, Y., Yao, Y., Cheng, G., & Yang, Y. (2023). Advanced Oxidation Nanoprocessing Boosts Immunogenicity of Whole Tumor Cells. Advanced Science, 10(22), 10 pages.
    DOI Scopus13 WoS7 Europe PMC8
    2023 Li, J., Lu, W., Yang, Y., Xiang, R., Ling, Y., Yu, C., & Zhou, Y. (2023). Hybrid Nanomaterials for Cancer Immunotherapy. Advanced Science, 10(6), 42 pages.
    DOI Scopus83 WoS81 Europe PMC53
    2023 Zhang, M., Wu, T., Zhang, H., Chen, Z., Yang, Y., Ling, Y., & Zhou, Y. (2023). Mesoporous carbon hemispheres integrated with Fe-Gd nanoparticles for potential MR/PA imaging-guided photothermal therapy. Journal of Materials Chemistry B, 12(3), 9 pages.
    DOI Scopus2 WoS2 Europe PMC1
    2023 Shi, Y., Dai, Z., Wang, Y., Luo, J., Cai, L., Tang, J., . . . Yang, Y. (2023). Engineering Crystallinity Gradients for Tailored CaO₂ Nanostructures: Enabling Alkalinity-Reinforced Anticancer Activity with Minimized Ca²⁺/H₂O₂ Production. Nano letters, 23(23), 10657-10666.
    DOI Scopus4 WoS4
    2022 Tang, J., Yang, Y., Qu, J., Ban, W., Song, H., Gu, Z., . . . Yu, C. (2022). Mesoporous sodium four-coordinate aluminosilicate nanoparticles modulate dendritic cell pyroptosis and activate innate and adaptive immunity. Chemical Science, 13(29), 8507-8517.
    DOI Scopus19 WoS19 Europe PMC15
    2022 Wang, F. Y., Qiu, T., Ling, Y., Yang, Y., & Zhou, Y. (2022). Physical and Chemical Cues at the Nano–Bio Interface for Immunomodulation. Angewandte Chemie International Edition, 61(41), 12 pages.
    DOI Scopus9 WoS11 Europe PMC5
    2022 Theivendran, S., Gu, Z., Tang, J., Yang, Y., Song, H., Yang, Y., . . . Yu, C. (2022). Nanostructured Organosilica Nitric Oxide Donors Intrinsically Regulate Macrophage Polarization with Antitumor Effect. ACS Nano, 16(7), 10943-10957.
    DOI Scopus68 WoS66 Europe PMC39
    2022 Yu, Z., Fang, W., Yang, Y., Yao, H., Hu, P., & Shi, J. (2022). Non-PCR Ultrasensitive Detection of Viral RNA by a Nanoprobe-Coupling Strategy: SARS-CoV-2 as an Example. Advanced Healthcare Materials, 11(17), 9 pages.
    DOI Scopus3 WoS3 Europe PMC3
    2022 Zhang, M., Feng, J., Zhong, Y., Luo, J., Zhao, Y., Yang, Y., . . . Yu, C. (2022). In-situ synthesis of Drug-Containing bactericidal rough silica nanoparticles for antibacterial coating. Chemical Engineering Journal, 440, 1-11.
    DOI Scopus21 WoS19
    2022 Wang, F., Qiu, T., Ling, Y., Yang, Y., & Zhou, Y. (2022). Physical and Chemical Cues at the Nano–Bio Interface for Immunomodulation. Angewandte Chemie, 134(41).
    DOI
    2022 Gao, F., Liu, C., Yao, Y., Lei, C., Li, S., Yuan, L., . . . Yu, C. (2022). Quantum dots’ size matters for balancing their quantity and quality in label materials to improve lateral flow immunoassay performance for C-reactive protein determination. Biosensors and Bioelectronics, 199, 1-8.
    DOI Scopus30 WoS30 Europe PMC14
    2022 Zhao, L., Zhang, Y., Yang, Y., & Yu, C. (2022). Silica-based Nanoparticles for Enzyme Immobilization and Delivery. Chemistry - An Asian Journal, 17(17), 1-9.
    DOI Scopus21 WoS20 Europe PMC8
    2022 Dai, Z., Wang, Q., Tang, J., Qu, R., Wu, M., Li, H., . . . Yu, C. (2022). A Sub-6 nm MnFe<inf>2</inf>O<inf>4</inf>-dichloroacetic acid nanocomposite modulates tumor metabolism and catabolism for reversing tumor immunosuppressive microenvironment and boosting immunotherapy. Biomaterials, 284, 11 pages.
    DOI Scopus36 WoS35 Europe PMC18
    2022 Dai, Z., Wang, Q., Tang, J., Wu, M., Li, H., Yang, Y., . . . Yu, C. (2022). Immune-regulating bimetallic metal-organic framework nanoparticles designed for cancer immunotherapy. Biomaterials, 280, 121261-1-121261-13.
    DOI Scopus52 WoS45 Europe PMC26
    2022 Kothalawala, S. G., Jiao, J., Speight, R., Song, H., Yang, Y., & Zhang, J. (2022). Pore architecture influences the enzyme immobilization performance of mesoporous silica nanospheres. Microporous and Mesoporous Materials, 338, 1-9.
    DOI Scopus21 WoS18
    2021 Yang, Y., Gu, Z., Tang, J., Zhang, M., Yang, Y., Song, H., & Yu, C. (2021). MnO<inf>2</inf> Nanoflowers Induce Immunogenic Cell Death under Nutrient Deprivation: Enabling an Orchestrated Cancer Starvation-Immunotherapy. Advanced Science, 8(4), 1-10.
    DOI Scopus55 WoS54
    2021 Luo, J., Zhang, M., Yang, Y., & Yu, C. (2021). Synthesis of dendritic mesoporous organosilica nanoparticles under a mild acidic condition with homogeneous wall structure and near-neutral surface. Chemical Communications, 57(36), 4416-4419.
    DOI Scopus6 WoS5 Europe PMC1
    2021 Zhang, M., Dai, Z., Theivendran, S., Gu, Z., Zhao, L., Song, H., . . . Yu, C. (2021). Nanotechnology enabled reactive species regulation in biosystems for boosting cancer immunotherapy. Nano Today, 36, 18 pages.
    DOI Scopus33 WoS31
    2021 Fu, J., Jiao, J., Ban, W., Kong, Y., Gu, Z., Song, H., . . . Yu, C. (2021). Large scale synthesis of self-assembled shuttlecock-shaped silica nanoparticles with minimized drag as advanced catalytic nanomotors. Chemical Engineering Journal, 417, 1-7.
    DOI Scopus17 WoS15
    2021 Lin, X., Wu, W., Fu, J., Yang, Y., Guo, B., Yu, C., & Song, H. (2021). Asymmetric Silica Nanoparticles with Tailored Spiky Coverage Derived from Silica-Polymer Cooperative Assembly for Enhanced Hemocompatibility and Gene Delivery. ACS Applied Materials and Interfaces, 13(43), 50695-50704.
    DOI Scopus16 WoS15 Europe PMC8
    2021 Song, Y., Cheng, D., Luo, J., Zhang, M., & Yang, Y. (2021). Surfactant-free synthesis of monodispersed organosilica particles with pure sulfide-bridged silsesquioxane framework chemistry via extension of Stöber method. Journal of Colloid and Interface Science, 591, 129-138.
    DOI Scopus11 WoS10 Europe PMC5
    2021 Yang, Y., Zhang, M., Yang, Y., Cheng, D., & Yu, C. (2021). Designer Anticancer Nanoprodrugs with Self-Toxification Activity Realized by Acid-triggered Biodegradation and In Situ Fragment Complexation. Angewandte Chemie - International Edition, 60(20), 11504-11513.
    DOI Scopus11 WoS12 Europe PMC2
    2021 Gu, Z., Liu, T., Liu, C., Yang, Y., Tang, J., Song, H., . . . Yu, C. (2021). Ferroptosis-Strengthened Metabolic and Inflammatory Regulation of Tumor-Associated Macrophages Provokes Potent Tumoricidal Activities. Nano Letters, 21(15), 6471-6479.
    DOI Scopus102 WoS98 Europe PMC79
    2021 Wang, Y., Song, H., Liu, C., Zhang, Y., Kong, Y., Tang, J., . . . Yu, C. (2021). Confined growth of ZIF-8 in dendritic mesoporous organosilica nanoparticles as bioregulators for enhanced mRNa delivery in vivo. National Science Review, 8(8), 10 pages.
    DOI Scopus37 WoS82 Europe PMC19
    2020 Wang, Y., Yang, Y., Shi, Y., Song, H., & Yu, C. (2020). Antibiotic-Free Antibacterial Strategies Enabled by Nanomaterials: Progress and Perspectives. Advanced Materials, 32(18), 1-21.
    DOI Scopus677 WoS663 Europe PMC264
    2020 Pei, C., Liu, C., Wang, Y., Cheng, D., Li, R., Shu, W., . . . Wan, J. (2020). FeOOH@Metal–Organic Framework Core–Satellite Nanocomposites for the Serum Metabolic Fingerprinting of Gynecological Cancers. Angewandte Chemie, 132(27), 10923-10927.
    DOI
    2020 Shi, Y., Fu, J., & Yang, Y. (2020). Effects of synthetic routes on the compositional and structural properties of dendritic mesoporous organosilica nanoparticles: The unexpected reversed “double-edged sword” role of reaction time. Microporous and Mesoporous Materials, 294, 1-8.
    DOI Scopus6 WoS5
    2020 Song, H., Yang, Y., Tang, J., Gu, Z., Wang, Y., Zhang, M., & Yu, C. (2020). DNA Vaccine Mediated by Rambutan-Like Mesoporous Silica Nanoparticles. Advanced Therapeutics, 3(1), 12 pages.
    DOI Scopus23 WoS21
    2020 Geng, J., Song, H., Gao, F., Kong, Y., Fu, J., Luo, J., . . . Yu, C. (2020). Lyophilization enabled disentanglement of polyethylenimine on rambutan-like silica nanoparticles for enhanced plasmid DNA delivery. Journal of Materials Chemistry B, 8(21), 4593-4600.
    DOI Scopus6 WoS6 Europe PMC4
    2020 Tang, J., Meka, A. K., Theivendran, S., Wang, Y., Yang, Y., Song, H., . . . Yu, C. (2020). Openwork@Dendritic Mesoporous Silica Nanoparticles for Lactate Depletion and Tumor Microenvironment Regulation. Angewandte Chemie - International Edition, 59(49), 22054-22062.
    DOI Scopus109 WoS110 Europe PMC66
    2020 Liu, Y., Kong, Y., Kumar Nanjundan, A., Yang, Y., Zhou, L., Huang, X., & Yu, C. (2020). Modulating the Void Space of Nitrogen-Doped Hollow Mesoporous Carbon Spheres for Lithium-Sulfur Batteries. ChemNanoMat, 6(6), 925-929.
    DOI Scopus7 WoS7
    2020 Dai, Z., Tang, J., Gu, Z., Wang, Y., Yang, Y., Yang, Y., & Yu, C. (2020). Eliciting Immunogenic Cell Death via a Unitized Nanoinducer. Nano Letters, 20(9), 6246-6254.
    DOI Scopus107 WoS105 Europe PMC52
    2020 Yang, Y., Zhang, M., Song, H., & Yu, C. (2020). Silica-Based Nanoparticles for Biomedical Applications: From Nanocarriers to Biomodulators. Accounts of Chemical Research, 53(8), 1545-1556.
    DOI Scopus185 WoS162 Europe PMC81
    2020 Theivendran, S., Tang, J., Lei, C., Yang, Y., Song, H., Gu, Z., . . . Yu, C. (2020). Post translational modification-assisted cancer immunotherapy for effective breast cancer treatment. Chemical Science, 11(38), 10421-10430.
    DOI Scopus15 WoS15 Europe PMC15
    2020 Jambhrunkar, M., Yang, Y., Yu, M., Zhang, M., Abbaraju, P. L., Ghosh, T., . . . Yu, C. (2020). Pristine large pore benzene-bridged mesoporous organosilica nanoparticles as an adjuvant and co-delivery platform for eliciting potent antitumor immunity. Materials Today Advances, 6, 8 pages.
    DOI Scopus26 WoS26
    2020 Wang, Y., Tang, J., Yang, Y., Song, H., Fu, J., Gu, Z., & Yu, C. (2020). Functional Nanoparticles with a Reducible Tetrasulfide Motif to Upregulate mRNA Translation and Enhance Transfection in Hard-to-Transfect Cells. Angewandte Chemie - International Edition, 59(7), 2695-2699.
    DOI Scopus58 WoS57 Europe PMC30
    2020 Yang, Y., Tang, J., Song, H., Yang, Y., Gu, Z., Fu, J., . . . Yu, C. (2020). Dendritic Mesoporous Silica Nanoparticle Adjuvants Modified with Binuclear Aluminum Complex: Coordination Chemistry Dictates Adjuvanticity. Angewandte Chemie - International Edition, 59(44), 19610-19617.
    DOI Scopus35 WoS35 Europe PMC12
    2020 Zhang, M., Yang, Y., Liu, Y., Fu, J., Lu, J., Yang, Y., . . . Yu, C. (2020). 3D-Nanosponge enabled segregation: A versatile approach for highly dispersed and high content functionalization of metal oxide species. Materials Chemistry Frontiers, 4(6), 1739-1746.
    DOI Scopus4 WoS3
    2020 Pei, C., Liu, C., Wang, Y., Cheng, D., Li, R., Shu, W., . . . Wan, J. (2020). FeOOH@Metal–Organic Framework Core–Satellite Nanocomposites for the Serum Metabolic Fingerprinting of Gynecological Cancers. Angewandte Chemie - International Edition, 59(27), 10831-10835.
    DOI Scopus131 WoS128 Europe PMC55
    2019 Theivendran, S., Zhang, J., Tang, C., Kalantari, M., Gu, Z., Yang, Y., . . . Yu, C. (2019). Synthesis of biphenyl bridged dendritic mesoporous organosilica with extremely high adsorption of pyrene. Journal of Materials Chemistry A, 7(19), 12029-12037.
    DOI Scopus24 WoS23
    2019 Gu, Z., Liu, T., Tang, J., Yang, Y., Song, H., Tuong, Z. K., . . . Yu, C. (2019). Mechanism of Iron Oxide-Induced Macrophage Activation: The Impact of Composition and the Underlying Signaling Pathway. Journal of the American Chemical Society, 141(15), 6122-6126.
    DOI Scopus162 WoS153 Europe PMC99
    2019 Yang, Y., Tang, J., Zhang, M., Gu, Z., Song, H., Yang, Y., & Yu, C. (2019). Responsively Aggregatable Sub-6 nm Nanochelators Induce Simultaneous Antiangiogenesis and Vascular Obstruction for Enhanced Tumor Vasculature Targeted Therapy. Nano Letters, 19(11), 7750-7759.
    DOI Scopus36 WoS31 Europe PMC17
    2019 Song, H., Yang, Y., Geng, J., Gu, Z., Zou, J., & Yu, C. (2019). Electron Tomography: A Unique Tool Solving Intricate Hollow Nanostructures. Advanced Materials, 31(38), 1801564.
    DOI Scopus43 WoS44 Europe PMC16
    2019 Fu, J., Gu, Z., Liu, Y., Zhang, J., Song, H., Yang, Y., . . . Yu, C. (2019). Bottom-up self-assembly of heterotrimeric nanoparticles and their secondary Janus generations. Chemical Science, 10(44), 10388-10394.
    DOI Scopus34 WoS31 Europe PMC9
    2018 Lu, Y., Yang, Y., Gu, Z., Zhang, J., Song, H., Xiang, G., & Yu, C. (2018). Glutathione-depletion mesoporous organosilica nanoparticles as a self-adjuvant and Co-delivery platform for enhanced cancer immunotherapy. Biomaterials, 175, 82-92.
    DOI Scopus158 WoS147 Europe PMC73
    2018 Zhang, M., Yang, Y., & Yu, C. (2018). Nano-resoles-Enabled Elegant Nanostructured Materials. Chemistry A European Journal, 24(55), 14598-14607.
    DOI Scopus8 WoS7 Europe PMC1
    2018 Yang, Y., Tang, J., Abbaraju, P. L., Jambhrunkar, M., Song, H., Zhang, M., . . . Yu, C. (2018). Hybrid Nanoreactors: Enabling an Off‐the‐Shelf Strategy for Concurrently Enhanced Chemo‐immunotherapy. Angewandte Chemie, 130(36), 11938-11943.
    DOI
    2018 Yang, Y., Lu, Y., Abbaraju, P. L., Azimi, I., Lei, C., Tang, J., . . . Yu, C. (2018). Stepwise Degradable Nanocarriers Enabled Cascade Delivery for Synergistic Cancer Therapy. Advanced Functional Materials, 28(28), 1-11.
    DOI Scopus112 WoS109
    2018 Zhang, J., Zhang, L., Lei, C., Huang, X., Yang, Y., & Yu, C. (2018). A Concentration-Dependent Insulin Immobilization Behavior of Alkyl-Modified Silica Vesicles: The Impact of Alkyl Chain Length. Langmuir, 34(17), 5011-5019.
    DOI Scopus6 WoS7 Europe PMC2
    2018 Liu, C., Huang, X., Wang, J., Song, H., Yang, Y., Liu, Y., . . . Yu, C. (2018). Hollow Mesoporous Carbon Nanocubes: Rigid-Interface-Induced Outward Contraction of Metal-Organic Frameworks. Advanced Functional Materials, 28(6), 1-8.
    DOI Scopus137 WoS126
    2018 Kalantari, M., Yu, M., Jambhrunkar, M., Liu, Y., Yang, Y., Huang, X., & Yu, C. (2018). Designed synthesis of organosilica nanoparticles for enzymatic biodiesel production. Materials Chemistry Frontiers, 2(7), 1334-1342.
    DOI Scopus31 WoS29
    2018 Abbaraju, P. L., Jambhrunkar, M., Yang, Y., Liu, Y., Lu, Y., & Yu, C. (2018). Asymmetric mesoporous silica nanoparticles as potent and safe immunoadjuvants provoke high immune responses. Chemical Communications, 54(16), 2020-2023.
    DOI Scopus49 WoS44 Europe PMC23
    2018 Zhang, M., Song, H., Yang, Y., Huang, X., Liu, Y., Liu, C., & Yu, C. (2018). Oxidative Dissolution of Resoles: A Versatile Approach to Intricate Nanostructures. Angewandte Chemie International Edition, 57(3), 654-658.
    DOI Scopus17 WoS16 Europe PMC3
    2018 Kalantari, M., Liu, Y., Strounina, E., Yang, Y., Song, H., & Yu, C. (2018). Superhydrophobic dendritic mesoporous organosilica nano-particles with ultrahigh-content of gradient organic moieties. Journal of Materials Chemistry A, 6(36), 17579-17586.
    DOI Scopus20 WoS19
    2018 Wang, Y., Song, H., Yu, M., Xu, C., Liu, Y., Tang, J., . . . Yu, C. (2018). Room temperature synthesis of dendritic mesoporous silica nanoparticles with small sizes and enhanced mRNA delivery performance. Journal of Materials Chemistry B, 6(24), 4089-4095.
    DOI Scopus68 WoS64 Europe PMC39
    2018 Wang, Y., Song, H., Yang, Y., Liu, Y., Tang, J., & Yu, C. (2018). Kinetically Controlled Dendritic Mesoporous Silica Nanoparticles: From Dahlia- to Pomegranate-like Structures by Micelle Filling. Chemistry of Materials, 30(16), 5770-5776.
    DOI Scopus47 WoS46
    2018 Yang, Y., Tang, J., Abbaraju, P. L., Jambhrunkar, M., Song, H., Zhang, M., . . . Yu, C. (2018). Hybrid Nanoreactors: Enabling an Off-the-Shelf Strategy for Concurrently Enhanced Chemo-immunotherapy. Angewandte Chemie - International Edition, 57(36), 11764-11769.
    DOI Scopus104 WoS108 Europe PMC43
    2018 Pan, D., Chen, W., Huang, X., Zhang, J., Yang, Y., Yu, F., . . . Yu, C. (2018). Solvothermal-assisted evaporation-induced self-assembly of ordered mesoporous alumina with improved performance. Journal of Colloid and Interface Science, 529, 432-443.
    DOI Scopus22 WoS18 Europe PMC3
    2017 Jiao, J., Fu, J., Wei, Y., Zhao, Z., Duan, A., Xu, C., . . . Liu, Y. (2017). Al-modified dendritic mesoporous silica nanospheres-supported NiMo catalysts for the hydrodesulfurization of dibenzothiophene: Efficient accessibility of active sites and suitable metal–support interaction. Journal of Catalysis, 356, 269-282.
    DOI Scopus104 WoS99
    2017 Abbaraju, P. L., Meka, A. K., Song, H., Yang, Y., Jambhrunkar, M., Zhang, J., . . . Yu, C. (2017). Asymmetric Silica Nanoparticles with Tunable Head-Tail Structures Enhance Hemocompatibility and Maturation of Immune Cells. Journal of the American Chemical Society, 139(18), 6321-6328.
    DOI Scopus125 WoS122 Europe PMC56
    2017 Kalantari, M., Yu, M., Yang, Y., Strounina, E., Gu, Z., Huang, X., . . . Yu, C. (2017). Tailoring mesoporous-silica nanoparticles for robust immobilization of lipase and biocatalysis. Nano Research, 10(2), 605-617.
    DOI Scopus71 WoS68
    2017 Purwajanti, S., Huang, X., Liu, Y., Yang, Y., Noonan, O., Song, H., . . . Yu, C. (2017). Mg(OH)2-MgO@reduced graphene oxide nanocomposites: The roles of composition and nanostructure in arsenite sorption. Journal of Materials Chemistry A, 5(46), 24484-24492.
    DOI Scopus27 WoS26
    2017 Abbaraju, P. L., Yang, Y., Yu, M., Fu, J., Xu, C., & Yu, C. (2017). Core–Shell-structured Dendritic Mesoporous Silica Nanoparticles for Combined Photodynamic Therapy and Antibody Delivery. Chemistry an Asian Journal, 12(13), 1465-1469.
    DOI Scopus24 WoS20 Europe PMC8
    2017 Lin, C. X. C., Xu, C., Yang, Y., Lei, C., Zhang, H., & Yu, C. (2017). Dendritic mesoporous silica-titania nanospheres with enhanced photocatalytic activities. New Journal of Chemistry, 41(17), 8754-8760.
    DOI Scopus17 WoS16
    2017 Yang, Y., Jambhrunkar, M., Abbaraju, P. L., Yu, M., Zhang, M., & Yu, C. (2017). Understanding the Effect of Surface Chemistry of Mesoporous Silica Nanorods on Their Vaccine Adjuvant Potency. Advanced Healthcare Materials, 6(17), 12 pages.
    DOI Scopus40 WoS43 Europe PMC17
    2017 Song, H., Yu, M., Lu, Y., Gu, Z., Yang, Y., Zhang, M., . . . Yu, C. (2017). Plasmid DNA Delivery: Nanotopography Matters. Journal of the American Chemical Society, 139(50), 18247-18254.
    DOI Scopus126 WoS117 Europe PMC71
    2017 Yang, Y., Lu, Y., Abbaraju, P. L., Zhang, J., Zhang, M., Xiang, G., & Yu, C. (2017). Multi-shelled Dendritic Mesoporous Organosilica Hollow Spheres: Roles of Composition and Architecture in Cancer Immunotherapy. Angewandte Chemie International Edition, 56(29), 8446-8450.
    DOI Scopus138 WoS140 Europe PMC55
    2016 Yang, Y., Bernardi, S., Song, H., Zhang, J., Yu, M., Reid, J. C., . . . Yu, C. (2016). Anion Assisted Synthesis of Large Pore Hollow Dendritic Mesoporous Organosilica Nanoparticles: Understanding the Composition Gradient. Chemistry of Materials, 28(3), 704-707.
    DOI Scopus225 WoS220
    2016 Hartono, S. B., Hadisoewignyo, L., Yang, Y., Meka, A. K., Antaresti., & Yu, C. (2016). Amine functionalized cubic mesoporous silica nanoparticles as an oral delivery system for curcumin bioavailability enhancement. NANOTECHNOLOGY, 27(50), 7 pages.
    DOI WoS49 Europe PMC21
    2016 Song, H., Ahmad Nor, Y., Yu, M., Yang, Y., Zhang, J., Zhang, H., . . . Yu, C. (2016). Silica Nanopollens Enhance Adhesion for Long-Term Bacterial Inhibition. Journal of the American Chemical Society, 138(20), 6455-6462.
    DOI Scopus255 WoS242 Europe PMC114
    2016 Yang, Y., Wan, J., Niu, Y., Gu, Z., Zhang, J., Yu, M., & Yu, C. (2016). Structure-Dependent and Glutathione-Responsive Biodegradable Dendritic Mesoporous Organosilica Nanoparticles for Safe Protein Delivery. Chemistry of Materials, 28(24), 9008-9016.
    DOI Scopus157 WoS155
    2016 Yang, Y., & Yu, C. (2016). Advances in silica based nanoparticles for targeted cancer therapy. Nanomedicine Nanotechnology Biology and Medicine, 12(2), 317-332.
    DOI Scopus170 WoS146 Europe PMC83
    2016 Yu, M., Niu, Y., Zhang, J., Zhang, H., Yang, Y., Taran, E., . . . Yu, C. (2016). Size-dependent gene delivery of amine-modified silica nanoparticles. Nano Research, 9(2), 291-305.
    DOI Scopus36 WoS35
    2016 Zhang, H., Noonan, O., Huang, X., Yang, Y., Xu, C., Zhou, L., & Yu, C. (2016). Surfactant-Free Assembly of Mesoporous Carbon Hollow Spheres with Large Tunable Pore Sizes. ACS Nano, 10(4), 4579-4586.
    DOI Scopus444 WoS427 Europe PMC109
    2016 Wang, Y., Nor, Y. A., Song, H., Yang, Y., Xu, C., Yu, M., & Yu, C. (2016). Small-sized and large-pore dendritic mesoporous silica nanoparticles enhance antimicrobial enzyme delivery. Journal of Materials Chemistry B, 4(15), 2646-2653.
    DOI Scopus96 WoS93 Europe PMC45
    2016 Purwajanti, S., Zhang, H., Huang, X., Song, H., Yang, Y., Zhang, J., . . . Yu, C. (2016). Mesoporous Magnesium Oxide Hollow Spheres as Superior Arsenite Adsorbent: Synthesis and Adsorption Behavior. ACS Applied Materials and Interfaces, 8(38), 25306-25312.
    DOI Scopus80 WoS73 Europe PMC15
    2016 Liu, Y., Zhang, H., Noonan, O., Xu, C., Niu, Y., Yang, Y., . . . Yu, C. (2016). Kinetically Controlled Assembly of Nitrogen-Doped Invaginated Carbon Nanospheres with Tunable Mesopores. Chemistry A European Journal, 22(42), 14962-14967.
    DOI Scopus23 WoS22 Europe PMC4
    2015 Niu, Y., Yu, M., Zhang, J., Yang, Y., Xu, C., Yeh, M., . . . Yu, C. (2015). Synthesis of silica nanoparticles with controllable surface roughness for therapeutic protein delivery. Journal of Materials Chemistry B, 3(43), 8477-8485.
    DOI Scopus42 WoS40 Europe PMC17
    2015 Yang, Y., Yu, M., Song, H., Wang, Y., & Yu, C. (2015). Preparation of fluorescent mesoporous hollow silica-fullerene nanoparticles via selective etching for combined chemotherapy and photodynamic therapy. Nanoscale, 7(28), 11894-11898.
    DOI Scopus27 WoS25 Europe PMC12
    2015 Xu, C., Yu, M., Noonan, O., Zhang, J., Song, H., Zhang, H., . . . Yu, C. (2015). Core-Cone Structured Monodispersed Mesoporous Silica Nanoparticles with Ultra-large Cavity for Protein Delivery. Small, 11(44), 5949-5955.
    DOI Scopus159 WoS154 Europe PMC64
    2015 Yang, Y., Niu, Y., Zhang, J., Meka, A. K., Zhang, H., Xu, C., . . . Yu, C. (2015). Biphasic Synthesis of Large-Pore and Well-Dispersed Benzene Bridged Mesoporous Organosilica Nanoparticles for Intracellular Protein Delivery. Small, 11(23), 2743-2749.
    DOI Scopus79 WoS80 Europe PMC37
    2015 Zhang, H., Yu, M., Song, H., Noonan, O., Zhang, J., Yang, Y., . . . Yu, C. (2015). Self-Organized Mesostructured Hollow Carbon Nanoparticles via a Surfactant-Free Sequential Heterogeneous Nucleation Pathway. Chemistry of Materials, 27(18), 6297-6304.
    DOI Scopus106 WoS105
    2015 Niu, Y., Yu, M., Meka, A., Liu, Y., Zhang, J., Yang, Y., & Yu, C. (2015). Understanding the contribution of surface roughness and hydrophobic modification of silica nanoparticles to enhanced therapeutic protein delivery. Journal of Materials Chemistry B, 4(2), 212-219.
    DOI Scopus80 WoS79 Europe PMC42
    2014 Yu, M., Niu, Y., Yang, Y., Hartono, S. B., Yang, J., Huang, X., . . . Yu, C. (2014). An approach to prepare polyethylenimine functionalized silica-based spheres with small size for siRNA delivery. ACS Applied Materials and Interfaces, 6(18), 15626-15631.
    DOI Scopus19 WoS18 Europe PMC8
    2014 Yang, Y., Karmakar, S., Yu, M., Popat, A., & Yu, C. (2014). Synthesis of silica vesicles with small sizes and reduced aggregation for photodynamic therapy. Chemistry Letters, 43(3), 316-318.
    DOI Scopus2 WoS2
    2014 Yang, Y., Karmakar, S., Zhang, J., Yu, M., Mitter, N., & Yu, C. (2014). Synthesis of SBA-15 rods with small sizes for enhanced cellular uptake. Journal of Materials Chemistry B, 2(30), 4929-4934.
    DOI Scopus25 WoS24 Europe PMC10
    2014 Zhang, J., Raphael, A. P., Yang, Y., Popat, A., Prow, T. W., & Yu, C. (2014). Nanodispersed UV blockers in skin-friendly silica vesicles with superior UV-attenuating efficiency. Journal of Materials Chemistry B, 2(44), 7673-7678.
    DOI Scopus17 WoS16 Europe PMC6
    2014 Yu, M., Karmakar, S., Yang, J., Zhang, H., Yang, Y., Thorn, P., & Yu, C. (2014). Facile synthesis of ultra-small hybrid silica spheres for enhanced penetration in 3D glioma spheroids. Chemical Communications, 50(13), 1527-1529.
    DOI Scopus15 WoS17 Europe PMC8

  • Theses
    Year Citation
    - Yang, Y. (n.d.). Development of a mesoporous silica based nanosystem for safe and efficient therapeutic delivery.
  • NHMRC Emerging Leadership Fellow (EL1), 2022-2026, Sole CI, $650,740
  • ARC Discovery Project 2020-2023, CI B, $395,000
  • UQ-Early Career Researcher Grant 2020.1-2020.12, Sole CI, $20,000
  • Position: Group Leader, Biomat & Immune Eng Lab (BIEL)
  • Phone: 83133776
  • Email: yannan.yang@adelaide.edu.au
  • Campus: West End Health Precinct
  • Building: AHMS - Adelaide Health and Medical Sciences, floor Ninth Floor
  • Room: 9069
  • Org Unit: South Australian Immunogenomics Cancer Institute
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