Zhenwei Lan

Zhenwei Lan

Higher Degree by Research Candidate

School of Chemical Engineering

Faculty of Sciences, Engineering and Technology

The advanced understanding of diseases underscores the pressing need for precision medicine, where LNP-based mRNA therapy offers considerable promise. Here, I will focus on the development of platform technology for mRNA-LNP adapting to precision medicine, streamlining the transition from diagnostic affirmation to drug availability, and mitigating the influence of factors such as mRNA itself and formula instability on products to a certain extent. Additionally, we will work to devise an integrated functional module to adapt to different source of data input, so that users can easily enter parameters to obtain the target product.

  • Language Competencies
    Language Competency
    Chinese (Mandarin) Can read, write, speak, understand spoken and peer review
    English Can read, write, speak, understand spoken and peer review

  • Education
    Date Institution name Country Title
    2019 - 2022 Guangdong Pharmaceutical University China Master of Medicine

  • Journals
    Year Citation
    2024 Jin, S., Lan, Z., Yang, G., Li, X., Shi, J. Q., Liu, Y., & Zhao, C. (2024). Computationally guided design and synthesis of dual‐drug loaded polymeric nanoparticles for combination therapy. Aggregate, 5(5), e606-1-e606-10.
    DOI
    2024 Yang, R., Cui, L., Xu, S., Zhong, Y., Xu, T., Liu, J., . . . Guo, Y. (2024). Membrane-Targeting Amphiphilic Honokiol Derivatives Containing an Oxazole Moiety as Potential Antibacterials against Methicillin-Resistant Staphylococcus aureus. Journal of Medicinal Chemistry, 67(18), 16858-16872.
    DOI Scopus2
    2024 Lan, Z., Chen, R., Zou, D., & Zhao, C. X. (2024). Microfluidic Nanoparticle Separation for Precision Medicine. Advanced Science, 38 pages.
    DOI
    2023 Ferlini Agne, G., & Feary, D. (2023). Nervous System Disorders Section 5: Pathophysiology and Treatment of Central Nervous System Trauma in the Foal. Unknown Journal, 1.
    Scopus1
    2022 Lan, Z., Zhang, Y., Lin, H., Sun, Y., Wang, S., & Meng, J. (2022). Efficient monitoring for the nutrient changes in stir-fried Moutan Cortex using non-destructive near-infrared spectroscopy sensors. Microchemical Journal, 183, 107972.
    DOI Scopus2
    2022 Lan, Z., Zhang, Y., Chen, X., Li, S., Cao, H., Wang, S., & Meng, J. (2022). Efficient Detection of Limonoid From Citrus Seeds by Handheld NIR: Compared with Benchtop NIR. Food Analytical Methods, 15(7), 1909-1921.
    DOI Scopus5
    2022 Li, S., Dong, L., Tang, K., Lan, Z., Liu, R., Wang, Y., . . . Lin, H. (2022). Simultaneous and trace level quantification of two potential genotoxic impurities in valsartan drug substance using UPLC-MS/MS. Journal of Pharmaceutical and Biomedical Analysis, 212, 6 pages.
    DOI Scopus14 Europe PMC1
    2021 Lan, Z., Zhang, Y., Sun, Y., Wang, L., Huang, Y., Cao, H., . . . Meng, J. (2021). Identifying of Anti-Thrombin Active Components From Curcumae Rhizoma by Affinity-Ultrafiltration Coupled With UPLC-Q-Exactive Orbitrap/MS. Frontiers in Pharmacology, 12.
    DOI Scopus9
    2021 Lan, Z., Zhang, Y., Zhang, Y., Liu, F., Ji, D., Cao, H., . . . Meng, J. (2021). Rapid evaluation on pharmacodynamics of Curcumae Rhizoma based on Micro-NIR and benchtop-NIR. Journal of Pharmaceutical and Biomedical Analysis, 200, 114074.
    DOI Scopus13 Europe PMC3
    2021 Lan, Z., Zhang, Y., Sun, Y., Ji, D., Wang, S., Lu, T., . . . Meng, J. (2021). Rapid quantitative detection of the discrepant compounds in differently processed Curcumae Rhizoma products by FT-NIR combined with VCPA-GA technology. Journal of Pharmaceutical and Biomedical Analysis, 195, 113837.
    DOI Scopus15 Europe PMC3
    2020 Lan, Z., Zhang, Y., Sun, Y., Ji, D., Wang, S., Lu, T., . . . Meng, J. (2020). A mid-level data fusion approach for evaluating the internal and external changes determined by FT-NIR, electronic nose and colorimeter in Curcumae Rhizoma processing. Journal of Pharmaceutical and Biomedical Analysis, 188, 113387.
    DOI Scopus41 Europe PMC8
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