Eric Gowans
School of Medicine
College of Health
Professor Eric Gowans.Professor Eric Gowans is an experienced molecular virologist who has worked on several of the hepatitis viruses throughout his career. His PhD studies examined the replication and pathogenesis of hepatitis B virus and later he worked on hepatitis delta virus. He has worked on hepatitis C virus (HCV) since the virus was discovered. More recently, he has worked on DNA and recombinant viral vectors as potential vaccines for human immunodeficiency virus (HIV) and HCV.
Professor Eric Gowans is an experienced molecular virologist who has worked on several of the hepatitis viruses throughout his career. His PhD studies examined the replication and pathogenesis of hepatitis B virus and later he worked on hepatitis delta virus. He has worked on hepatitis C virus (HCV) since the virus was discovered. More recently, he has worked on DNA and recombinant viral vectors as potential vaccines for human immunodeficiency virus (HIV) and HCV.
For more information please follow the link: http://www.basilhetzelinstitute.com.au/profile/eric-gowans/
| Date | Position | Institution name |
|---|---|---|
| 2010 - ongoing | Senior Research Fellow | University of Adelaide, Adelaide |
| 2008 - 2009 | Executive Director | Women's & Children's Health Research Institute, North Adelaide |
| Date | Institution name | Country | Title |
|---|---|---|---|
| Napier College | United Kingdom | Fellow of Institute of Medical Laboratory Science | |
| University of South Australia, Adelaide | Australia | M. App. Sc. | |
| University of Adelaide, Adelaide | Australia | PhD |
| Year | Citation |
|---|---|
| 2023 | Wijesundara, D. K., Yeow, A., McMillan, C. L. D., Choo, J. J. Y., Todorovic, A., Mekonnen, Z. A., . . . Muller, D. A. (2023). Superior efficacy of a skin-applied microprojection device for delivering a novel Zika DNA vaccine. Molecular Therapy Nucleic Acids, 34, 102056-1-102056-10. Scopus9 WoS8 Europe PMC7 |
| 2022 | Kovoor, J. G., Jacobsen, J. H. W., Duncan, J., Addo, A. A., Tivey, D. R., Babidge, W. J., . . . Maddern, G. J. (2022). Achieving safe surgery after COVID-19 vaccination.. ANZ J Surg, 92(5), 946-949. Scopus3 WoS2 Europe PMC2 |
| 2022 | Garcia-Valtanen, P., Hope, C. M., Masavuli, M. G., Yeow, A. E. L., Balachandran, H., Mekonnen, Z. A., . . . Grubor-Bauk., B. (2022). SARS-CoV-2 Omicron variant escapes neutralising antibodies and T cell responses more efficiently than other variants in mild COVID-19 convalescents.. Cell Reports Medicine, 3(6), 100651-1-100651-17. Scopus34 WoS33 Europe PMC30 |
| 2021 | Garcia-Valtanen, P., Hope, C. M., Masavuli, M. G., Yeow, A. E. L., Balachandran, H., Mekonnen, Z. A., . . . Grubor-Bauk, B. (2021). COVID-19 convalescents exhibit deficient humoral and T cell responses to variant of concern Spike antigens at 12 month post-infection. |
| 2020 | Gummow, J., Masavuli, M., Mekonnen, Z. A., Li, Y., Wijesundara, D. K., Shrestha, A. C., . . . Grubor-Bauk, B. (2020). Safety profile of a multi-antigenic DNA vaccine against hepatitis C virus. Vaccines, 8(1), 1-15. Scopus11 WoS9 Europe PMC7 |
| 2020 | Mekonnen, Z. A., Masavuli, M. G., Yu, W., Gummow, J., Whelan, D. M., Al-Delfi, Z., . . . Grubor-Bauk, B. (2020). Enhanced T cell responses induced by a necrotic dendritic cell vaccine, expressing HCV NS3. Front Microbiol, 11, 1-13. Scopus8 WoS5 Europe PMC5 |
| 2019 | Grubor-Bauk, B., Wijesundara, D. K., Masavuli, M., Abbink, P., Peterson, R. L., Prow, N. A., . . . Gowans, E. J. (2019). NS1 DNA vaccination protects against Zika infection through T cell-mediated immunity in immunocompetent mice.. Sci Adv, 5(12), eaax2388. Scopus65 WoS56 Europe PMC54 |
| 2019 | Roy, S., Jaeson, M., Li, Z., Mahboob, S., Jackson, R., Grubor-Bauk, B., . . . Ranasinghe, C. (2019). Viral vector and route of administration determine the ILC and DC profiles responsible for downstream vaccine-specific immune outcomes. Vaccine, 37(10), 1266-1276. Scopus18 WoS16 Europe PMC15 |
| 2019 | Mekonnen, Z. A., Grubor-Bauk, B., Masavuli, M. G., Shrestha, A. C., Ranasinghe, C., Bull, R. A., . . . Wijesundara, D. K. (2019). Toward DNA-based T-cell mediated vaccines to target HIV-1 and hepatitis C virus: approaches to elicit localized immunity for protection. Frontiers in Cellular and Infection Microbiology, 9(APR), 1-8. Scopus14 WoS10 Europe PMC9 |
| 2019 | Shrestha, A. C., Wijesundara, D. K., Masavuli, M. G., Mekonnen, Z. A., Gowans, E. J., & Grubor-Bauk, B. (2019). Cytolytic perforin as an adjuvant to enhance the immunogenicity of DNA vaccines. Vaccines, 7(2), 14 pages. Scopus12 WoS12 Europe PMC10 |
| 2019 | Masavuli, M. G., Wijesundara, D. K., Underwood, A., Christiansen, D., Earnest-Silveira, L., Bull, R., . . . Grubor-Bauk, B. (2019). A hepatitis C virus DNA vaccine encoding a secreted, oligomerized form of envelope proteins is highly immunogenic and elicits neutralizing antibodies in vaccinated mice. Frontiers in immunology, 10(MAY), 1-19. Scopus34 WoS30 Europe PMC27 |
| 2019 | Christiansen, D., Earnest-Silveira, L., Grubor-Bauk, B., Wijesundara, D. K., Boo, I., Ramsland, P. A., . . . Torresi, J. (2019). Pre-clinical evaluation of a quadrivalent HCV VLP vaccine in pigs following microneedle delivery. Scientific Reports, 9(1), 1-13. Scopus57 WoS52 Europe PMC48 |
| 2019 | Mekonnen, Z. A., Grubor-Bauk, B., English, K., Leung, P., Masavuli, M. G., Shrestha, A. C., . . . Wijesundara, D. K. (2019). Single-dose vaccination with a hepatotropic adeno-associated virus efficiently localizes T cell immunity in the liver with the potential to confer rapid protection against Hepatitis C virus. Journal of Virology, 93(19), e00202-19-1-e00202-19-19. Scopus17 WoS18 Europe PMC18 |
| 2018 | Wijesundara, D., Gummow, J., Li, Y., Yu, W., Quah, B., Ranasinghe, C., . . . Grubor-Bauk, B. (2018). Induction of genotype-cross reactive, hepatitis C virus-specific cell mediated immunity in DNA-vaccinated mice. Journal of Virology, 92(8), 1-15. Scopus21 WoS22 Europe PMC21 |
| 2018 | Christiansen, D., Earnest-Silveira, L., Chua, B., Boo, I., Drummer, H. E., Grubor-Bauk, B., . . . Torresi, J. (2018). Antibody responses to a quadrivalent Hepatitis C viral-like particle vaccine adjuvanted with Toll-like receptor 2 agonists. Viral Immunology, 31(4), 1-6. Scopus11 WoS10 Europe PMC10 |
| 2018 | Christiansen, D., Earnest-Silveira, L., Chua, B., Meuleman, P., Boo, I., Grubor-Bauk, B., . . . Torresi, J. (2018). Immunological responses following administration of a genotype 1a/1b/2/3a quadrivalent HCV VLP vaccine. Scientific Reports, 8(1), 6483-1-6483-13. Scopus41 WoS35 Europe PMC34 |
| 2017 | Wijesundara, D., Yu, W., Quah, B., Eldi, P., Hayball, J., Diener, K., . . . Grubor-Bauk, B. (2017). Cytolytic DNA vaccine encoding lytic perforin augments the maturation of- and antigen presentation by- dendritic cells in a time-dependent manner. Scientific Reports, 7(1), 8530-1-8530-8. Scopus8 WoS9 Europe PMC9 |
| 2017 | Wijesundara, D., Ranasinghe, C., Grubor-Bauk, B., & Gowans, E. (2017). Emerging targets for developing T cell-mediated vaccines for human immunodeficiency virus (HIV)-1. Frontiers in Microbiology, 8(OCT), 2091-1-2091-7. Scopus12 WoS11 Europe PMC9 |
| 2017 | Masavuli, M., Wijesundara, D., Torresi, J., Gowans, E., & Grubor-Bauk, B. (2017). Preclinical development and production of virus-like particles as vaccine candidates for hepatitis C. Frontiers in Microbiology, 8(DEC), 11 pages. Scopus39 WoS30 Europe PMC30 |
| 2016 | Tomusange, K., Wijesundara, D., Gummow, J., Wesselingh, S., Suhrbier, A., Gowans, E., & Grubor-Bauk, B. (2016). Mucosal vaccination with a live recombinant rhinovirus followed by intradermal DNA administration elicits potent and protective HIV-specific immune responses. Scientific Reports, 6(1), 36658 -1-36658-11. Scopus10 WoS10 Europe PMC10 |
| 2016 | Kumar, A., Das, S., Mullick, R., Lahiri, P., Tatineni, R., Goswami, D., . . . Das, S. (2016). Immune responses against hepatitis C virus genotype 3a virus-like particles in mice: a novel VLP prime-adenovirus boost strategy. Vaccine, 34(8), 1115-1125. Scopus23 WoS21 Europe PMC19 |
| 2016 | Earnest-Silveira, L., Chua, B., Chin, R., Christiansen, D., Johnson, D., Herrmann, S., . . . Torresi, J. (2016). Characterization of a hepatitis C virus-like particle vaccine produced in a human hepatocyte-derived cell line. Journal of General Virology, 97(8), 1865-1876. Scopus29 WoS28 Europe PMC28 |
| 2016 | Tomusange, K., Wijesundara, D., Gummow, J., Garrod, T., Li, Y., Gray, L., . . . Gowans, E. (2016). A HIV-Tat/C4-binding protein chimera encoded by a DNA vaccine is highly immunogenic and contains acute EcoHIV infection in mice. Scientific Reports, 6(1), 29131-1-29131-10. Scopus19 WoS19 Europe PMC18 |
| 2016 | Earnest-Silveira, L., Christiansen, D., Herrmann, S., Ralph, S., Das, S., Gowans, E., & Torresi, J. (2016). Large scale production of a mammalian cell derived quadrivalent hepatitis C virus like particle vaccine. Journal of Virological Methods, 236, 87-92. Scopus22 WoS20 Europe PMC17 |
| 2016 | Jorritsma, S., Gowans, E., Grubor-Bauk, B., & Wijesundara, D. (2016). Delivery methods to increase cellular uptake and immunogenicity of DNA vaccines. Vaccine, 34(46), 5488-5494. Scopus117 WoS107 Europe PMC96 |
| 2016 | Grubor-Bauk, B., Yu, W., Wijesundara, D., Gummow, J., Garrod, T., Brennan, A., . . . Gowans, E. (2016). Intradermal delivery of DNA encoding HCV NS3 and perforin elicits robust cell-mediated immunity in mice and pigs. Gene Therapy, 23(1), 26-37. Scopus25 WoS24 Europe PMC23 |
| 2015 | Li, S., Plebanski, M., Smooker, P., & Gowans, E. J. (2015). Editorial: Why vaccines to HIV, HCV, and malaria have so far failed-challenges to developing vaccines against immunoregulating pathogens. Frontiers in Microbiology, 6(NOV), 3 pages. Scopus13 WoS11 Europe PMC14 |
| 2015 | Gummow, J., Li, Y., Yu, W., Garrod, T., Wijesundara, D., Brennan, A., . . . Gowans, E. (2015). A multiantigenic DNA vaccine that induces broad hepatitis C virus-specific T-Cell responses in mice. Journal of Virology, 89(15), 7991-8002. Scopus23 WoS24 Europe PMC22 |
| 2015 | Tomusange, K., Yu, W., Suhrbier, A., Wijesundara, D., Grubor-Bauk, B., & Gowans, E. (2015). Engineering human rhinovirus serotype-A1 as a vaccine vector. Virus Research, 203, 72-76. Scopus7 WoS6 Europe PMC4 |
| 2014 | Yu, W., Grubor-Bauk, B., Mullick, R., Das, S., & Gowans, E. J. (2014). Immunocompetent mouse models to evaluate intrahepatic T cell responses to HCV vaccines. HUMAN VACCINES & IMMUNOTHERAPEUTICS, 10(12), 3576-3578. WoS2 |
| 2014 | Gargett, T., Grubor-Bauk, B., Miller, D., Garrod, T., Yu, S., Wesselingh, S., . . . Gowans, E. (2014). Increase in DNA vaccine efficacy by virosome delivery and co-expression of a cytolytic protein. Clinical and Translational Immunology, 3(6), e18-1-e18-7. Scopus23 WoS20 Europe PMC20 |
| 2014 | Yu, W., Grubor-Bauk, B., Mullick, R., Das, S., & Gowans, E. J. (2014). Immunocompetent mouse models to evaluate intrahepatic T cell responses to HCV vaccines. Human vaccines & immunotherapeutics, 10(12), 3576-3578. Scopus3 Europe PMC3 |
| 2014 | Garrod, T., Grubor-Bauk, B., Yu, S., Gargett, T., & Gowans, E. (2014). Encoded novel forms of HSP70 or a cytolytic protein increase DNA vaccine potency.. Human vaccines & immunotherapeutics, 10(9). |
| 2014 | Garrod, T., Gargett, T., Yu, W., Major, L., Burrell, C., Wesselingh, S., . . . Gowans, E. (2014). Loss of long term protection with the inclusion of HIV pol to a DNA vaccine encoding gag. Virus Research, 192, 25-33. Scopus6 WoS6 Europe PMC6 |
| 2014 | Garrod, T., Grubor-Bauk, B., Gargett, T., Li, Y., Miller, D., Yu, W., . . . Gowans, E. (2014). DNA vaccines encoding membrane-bound or secreted forms of heat shock protein 70 exhibit improved potency. European Journal of Immunology, 44(7), 1992-2002. Scopus24 WoS21 Europe PMC19 |
| 2014 | Beard, M. R., Ffrench, R., Gowans, E. J., Helbig, K. J., Eyre, N. M., Douglas, M. M. W., . . . Drummer, H. E. (2014). A summary of the 20th International Symposium on Hepatitis C Virus and Related Viruses. Gastroenterology, 147(1), e1-e4. Scopus1 WoS1 |
| 2014 | Garrod, T., Grubor-Bauk, B., Yu, S., Gargett, T., & Gowans, E. (2014). Encoded novel forms of HSP70 or a cytolytic protein increase DNA vaccine potency. Human Vaccines and Immunotherapeutics, 10(9), 2679-2683. Scopus10 WoS11 Europe PMC9 |
| 2014 | Gargett, T., Grubor-Bauk, B., Garrod, T., Yu, W., Miller, D., Major, L., . . . Gowans, E. (2014). Induction of antigen-positive cell death by the expression of Perforin, but not DTa, from a DNA vaccine enhances the immune response. Immunology and Cell Biology, 92(4), 359-367. Scopus24 WoS25 Europe PMC24 |
| 2014 | Yu, W., Grubor-Bauk, B., Gargett, T., Garrod, T., & Gowans, E. (2014). A novel challenge model to evaluate the efficacy of hepatitis C virus vaccines in mice. Vaccine, 32(27), 3409-3416. Scopus17 WoS16 Europe PMC12 |
| 2013 | Gouklani, H., Beyer, C., Drummer, H., Gowans, E., Netter, H., & Haqshenas, G. (2013). Identification of specific regions in hepatitis C virus core, NS2 and NS5A that genetically interact with p7 and co-ordinate infectious virus production. Journal of Viral Hepatitis, 20(4), e66-e71. Scopus14 WoS13 Europe PMC13 |
| 2013 | Li, S., Lefranc, M., Miles, J., Alamyar, E., Giudicelli, V., Duroux, P., . . . Gowans, E. (2013). IMGT/HighV QUEST paradigm for T cell receptor IMGT clonotype diversity and next generation repertoire immunoprofiling. Nature Communications, 4(1), 1-13. Scopus182 WoS161 Europe PMC169 |
| 2012 | Li, S., Roberts, S., Plebanski, M., Gouillou, M., Spelman, T., Latour, P., . . . Gowans, E. (2012). Induction of multi-functional T cells in a phase I clinical trial of dendritic cell immunotherapy in Hepatitis C virus infected individuals. PLoS One, 7(8), 1-7. Scopus10 WoS8 Europe PMC7 |
| 2012 | Wong, S., Haqshenas, G., Gowans, E., & MacKenzie, J. (2012). The dengue virus M protein localises to the endoplasmic reticulum and forms oligomers. FEBS Letters, 586(7), 1032-1037. Scopus11 WoS11 Europe PMC10 |
| 2012 | Gorzin, A., Ramsland, P., Tachedjian, G., & Gowans, E. (2012). Identification of residues involved in NS2 homodimerization and elucidation of their impact on the HCV life cycle. Journal of Viral Hepatitis, 19(3), 189-198. Scopus7 WoS6 Europe PMC5 |
| 2012 | Gouklani, H., Bull, R., Beyer, C., Coulibaly, F., Gowans, E., Drummer, H., . . . Haqshenas, G. (2012). Hepatitis C virus nonstructural protein 5B is involved in virus morphogenesis. Journal of Virology, 86(9), 5080-5088. Scopus34 WoS36 Europe PMC32 |
| 2011 | Wong, S. -S., Chebib, M., Haqshenas, G., Loveland, B., & Gowans, E. J. (2011). Dengue virus PrM/M proteins fail to show pH-dependent ion channel activity in Xenopus oocytes. Virology, 412(1), 83-90. Scopus7 WoS10 Europe PMC9 |
| 2010 | Gowans, E., Roberts, S., Jones, K., Dinatale, I., Latour, P., Chua, B., . . . Jackson, D. (2010). A phase I clinical trial of dendritic cell immunotherapy in HCV-infected individuals. Journal of Hepatology, 53(4), 599-607. Scopus55 WoS50 Europe PMC41 |
| 2009 | Meshkat, Z., Audsley, M., Beyer, C., Gowans, E., & Haqshenas, G. (2009). Reverse genetic analysis of a putative, influenze virus M2 HXXXW-like motif in the p7 protein of hepatitis C virus. Journal of Viral Hepatitis, 16(3), 187-194. Scopus20 WoS20 Europe PMC19 |
| 2009 | Martyn, J., Cardin, A., Wines, B., Cendron, A., Li, S., MacKenzie, J., . . . Gowans, E. (2009). Surface display of IgG Fc on baculovirus vectors enhances binding to antigen-presenting cells and cell lines expressing Fc receptors. Archives of Virology, 154(7), 1129-1138. Scopus36 WoS33 Europe PMC27 |
| 2009 | Li, S., Floess, S., Hamann, A., Gaudieri, S., Lucas, A., Hellard, M., . . . Gowans, E. (2009). Analysis of FOXP3+ regulatory T cells that display apparent viral antigen specificity during chronic hepatitis C virus infection. PLoS Pathogens, 5(12), 1000707-1-1000707-13. Scopus30 WoS44 Europe PMC28 |
| 2008 | Jones, K., Brown, L., Eriksson, E., Ffrench, R., Latour, P., Loveland, B., . . . Gowans, E. (2008). Human dendritic cells pulsed with specific lipopeptides stimulate autologous antigen-specific T cells without the addition of exogenous maturation factors. Journal of Viral Hepatitis, 15(10), 761-772. Scopus13 WoS12 Europe PMC9 |
| 2008 | Li, S., Gowans, E., Chougnet, C., Plebanski, M., & Dittmer, U. (2008). Natural Regulatory T Cells and Persistent Viral Infection. Journal of Virology, 82(1), 21-30. Scopus131 WoS124 Europe PMC115 |
| 2008 | Chua, B., Eriksson, E., Brown, L., Zeng, W., Gowans, E., Torresi, J., & Jackson, D. (2008). A self-adjuvanting lipopeptide-based vaccine candidate for the treatment of hepatitis C virus infection. Vaccine, 26(37), 4866-4875. Scopus51 WoS47 Europe PMC39 |
| 2008 | Woollard, D., Haqshenas, G., Dong, X., Pratt, B., Kent, S., & Gowans, E. (2008). Virus-specific T-cell immunity correlates with control of gb virus b infection in marmosets. Journal of Virology, 82(6), 3054-3060. Scopus27 WoS26 Europe PMC26 |
| 2007 | Jones, K., Drane, D., & Gowans, E. (2007). Long-term storage of DNA-free RNA for use in vaccine studies. Biotechniques, 43(5), 675-681. Scopus104 WoS90 Europe PMC75 |
| 2007 | Chin, R., Earnest-Silveria, L., Koeberlain, B., Franz, S., Zentgraf, H., Dong, X., . . . Torresi, J. (2007). Modulation of MAPK pathways and cell cycle by replicating hepatitis B virus: Factors contributing to hepatocarcinogenesis. Journal of Hepatology, 47(3), 325-337. Scopus64 WoS59 Europe PMC54 |
| 2007 | Haqshenas, G., Dong, X., Netter, H., Torresi, J., & Gowans, E. (2007). A chimeric GB virus B encoding the hepatitis C virus hypervariable region 1 is infectious in vivo. Journal of General Virology, 88(3), 895-902. Scopus26 WoS24 Europe PMC23 |
| 2007 | Li, S., Jones, K., Woollard, D., Dromey, J., Paukovics, G., Plebanski, M., & Gowans, E. (2007). Defining target antigens for CD25⁺FOXP3⁺IFN-γ⁻ regulatory T cells in chronic hepatitis C virus infection. Immunology and Cell Biology, 85(3), 197-204. Scopus57 WoS57 Europe PMC47 |
| 2007 | Haqshenas, G., Mackenzie, J., Dong, X., & Gowans, E. (2007). Hepatitis C virus p7 protein is localized in the endoplasmic reticulum when it is encoded by a replication-competent genome. Journal of General Virology, 88(1), 134-142. Scopus37 WoS36 Europe PMC32 |
| 2007 | Haqshenas, G., Dong, X., Ewart, G., Bowden, S., & Gowans, E. (2007). A 2a/1b full-length p7 inter-genotypic chimeric genome of hepatitis C virus is infectious in vitro. Virology, 360(1), 17-26. Scopus16 WoS17 Europe PMC17 |
| 2007 | Martyn, J., Dong, X., Holmes-Brown, S., Pribul, P., Li, S., Drummer, H., & Gowans, E. (2007). Transient and stable expression of the HCV envelope glycoproteins in cell lines and primary hepatocytes transduced with a recombinant baculovirus. Archives of Virology, 152(2), 329-343. Scopus15 WoS14 Europe PMC10 |
| 2006 | Dong, X., Premkumar, A., Haqshenas, G., Gage, P., & Gowans, E. (2006). Amantadine inhibits the function of an ion channel encoded by GB virus-B but fails to inhibit virus replication. Journal of Clinical Virology, 36, S113. |
| 2006 | Premkumar, A., Dong, X., Haqshenas, G., Gage, P. W., & Gowans, E. J. (2006). Amantadine inhibits the function of an ion channel encoded by GB virus B, but fails to inhibit virus replication. Antiviral Therapy, 11(3), 289-295. Scopus13 WoS12 Europe PMC12 |
| 2005 | Jackson, D., Deliyannis, G., Eriksson, E., Dinatale, I., & Gowans, E. (2005). Dendritic Cell Immunotherapy of Hepatitis C Virus Infection: Toxicology of Lipopeptide-Loaded Dendritic Cells. International Journal of Peptide Research and Therapeutics, 11(4), 223-235. Scopus8 WoS8 |
| 2005 | Mijch, A., Sasadeusz, J., Hellard, M., Dunne, M., McCaw, R., Bowden, S., & Gowans, E. (2005). A study to investigate the impact of the initiation of highly active antiretroviral therapy on the hepatitis C virus viral load in HIV/HCV-coinfected patients. Antiviral Therapy, 10(2), 277-284. Scopus3 WoS3 Europe PMC3 |
| 2004 | Gowans, E. J., Jones, K. L., Bharadwaj, M., & Jackson, D. C. (2004). Prospects for dendritic cell vaccination in persistent infection with hepatitis C virus. Journal of Clinical Virology, 30(4), 283-290. Scopus31 WoS29 Europe PMC22 |
| 2004 | Li, D., Lott, W. B., Martyn, J., Haqshenas, G., & Gowans, E. J. (2004). Differential effects on the hepatitis C virus (HCV) internal ribosome entry site by vitamin B 12 and the HCV core protein. Journal of Virology, 78(21), 12075-12081. Scopus17 WoS15 Europe PMC17 |
| 2004 | Torresi, J., Bharadwaj, M., Jackson, D. C., & Gowans, E. J. (2004). Neutralising antibody, CTL and dendritic cell responses to hepatitis C virus: A preventive vaccine strategy. Current Drug Targets, 5(1), 41-56. Scopus19 WoS20 Europe PMC17 |
| 2003 | Ward, S. M., Tindle, R. W., Khromykh, A. A., & Gowans, E. J. (2003). Generation of CTL responses using Kunjin replicon RNA. Immunology and Cell Biology, 81(1), 73-78. Scopus4 WoS4 Europe PMC3 |
| 2003 | Fowler, N. L., Torresi, J., Jackson, D. C., Brown, L. E., & Gowans, E. J. (2003). Immune responses in hepatitis C virus infection: The role of dendritic cells. Immunology and Cell Biology, 81(1), 63-66. Scopus10 WoS8 Europe PMC9 |
| 2003 | Chuan, B. Y., Healy, A., Cameron, P. U., Stock, O., Rizkalla, M., Zeng, W., . . . Jackson, D. C. (2003). Maturation of dendritic cells with lipopeptides that represent vaccine candidates for hepatitis C virus. Immunology and Cell Biology, 81(1), 67-72. Scopus34 WoS32 Europe PMC20 |
| 2003 | Netter, H. J., Woo, W. P., Tindle, R., Macfarlan, R. I., & Gowans, E. J. (2003). Immunogenicity of recombinant HBsAg/HCV particles in mice pre-immunised with hepatitis B virus-specific vaccine. Vaccine, 21(21-22), 2692-2697. Scopus28 WoS22 Europe PMC21 |
| 2003 | Li, D., Takyar, S. T., Lott, W. B., & Gowans, E. J. (2003). Amino acids 1-20 of the hepatitis C virus (HCV) core protein specifically inhibit HCV IRES-dependent translation in HepG2 cells, and inhibit both HCV IRES- and cap-dependent translation in HuH7 and CV-1 cells. Journal of General Virology, 84(4), 815-825. Scopus37 WoS34 Europe PMC31 |
| 2002 | Greive, S. J., Webb, R. I., Mackenzie, J. M., & Gowans, E. J. (2002). Expression of the hepatitis C virus structural proteins in mammalian cells induces morphology similar to that in natural infection. Journal of Viral Hepatitis, 9(1), 9-17. Scopus14 WoS12 Europe PMC8 |
| 2002 | Takyar, S. S., Gowans, E. J., & Lott, W. B. (2002). Vitamin B12 stalls the 80 S ribosomal complex on the hepatitis C internal ribosome entry site. Journal of Molecular Biology, 319(1), 1-8. Scopus18 WoS15 Europe PMC13 |
| 2001 | Lott, W. B., Takyar, S. S., Tuppen, J., Crawford, D. H. G., Harrison, M., Sloots, T. P., & Gowans, E. J. (2001). Vitamin B12 and hepatitis C: Molecular biology and human pathology. Proceedings of the National Academy of Sciences of the United States of America, 98(9), 4916-4921. Scopus35 WoS33 Europe PMC29 |
| 2001 | Ward, S. M., Macnaughton, T. B., & Gowans, E. J. (2001). Development and characterisation of recombinant hepatitis delta virus-like particles. Virus Genes, 23(1), 97-104. Scopus2 WoS2 Europe PMC1 |
| 2001 | Netter, H. J., Macnaughton, T. B., Woo, W. P., Tindle, R., & Gowans, E. J. (2001). Antigenicity and immunogenicity of novel chimeric hepatitis B surface antigen particles with exposed hepatitis C virus epitopes. Journal of Virology, 75(5), 2130-2141. Scopus83 WoS73 Europe PMC61 |
| 2000 | Takyar, S. T., Li, D. S., Wang, Y. H., Trowbridge, R., & Gowans, E. J. (2000). Specific detection of minus-strand hepatitis C virus RNA by reverse- transcription polymerase chain reaction on polyA+-purified RNA. Hepatology, 32(2), 382-387. Scopus33 WoS32 Europe PMC29 |
| 2000 | Warrilow, D., Lott, W. B., Greive, S., & Gowans, E. J. (2000). Properties of the bovine viral diarrhoea virus replicase in extracts of infected MDBK cells. Archives of Virology, 145(10), 2163-2171. Scopus8 WoS8 Europe PMC6 |
| 2000 | Gowans, E. J. (2000). Distribution of markers of hepatitis C virus infection throughout the body. Seminars in Liver Disease, 20(1), 85-102. Scopus90 WoS78 Europe PMC62 |
| 2000 | Mison, L. M., Hyland, C. A., Poidinger, M., Borthwick, I. A., Faoagali, J., Aeno, U., & Gowans, E. J. (2000). Hepatitis G virus genotypes in Australia, Papua New Guinea and the Solomon Islands: A possible new Pacific type identified. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 15(8), 952-956. WoS7 |
| 1999 | Harvey, T. J., Macnaughton, T. B., Park, D. S., & Gowans, E. J. (1999). A cellular protein which binds hepatitis B virus but not hepatitis B surface antigen. Journal of General Virology, 80(3), 607-615. Scopus8 WoS4 Europe PMC4 |
| 1998 | Gong, Y., Shannon, A., Westaway, E. G., & Gowans, E. J. (1998). The replicative intermediate molecule of bovine viral diarrhoea virus contains multiple nascent strands. Archives of Virology, 143(2), 399-404. Scopus17 WoS17 Europe PMC12 |
| 1998 | Gong, Y., Trowbridge, R., MacKintosh, S., Shannon, A., & Gowans, E. J. (1998). A stable cell line with a proportion of cells persistently infected with bovine viral diarrhoea virus. Veterinary Microbiology, 63(2-4), 117-124. Scopus3 WoS3 Europe PMC3 |
| 1998 | Trowbridge, R., & Gowans, E. J. (1998). Molecular cloning of an Australian isolate of hepatitis C virus. Archives of Virology, 143(3), 501-511. Scopus18 WoS19 Europe PMC16 |
| 1998 | Trowridge, R., & Gowans, E. J. (1998). Identification of novel sequences at the 5′ terminus of the hepatitis C virus genome. Journal of Viral Hepatitis, 5(2), 95-98. Scopus13 WoS13 Europe PMC12 |
| 1998 | Hyland, C. A., Mison, L., Solomon, N., Cockerill, J., Wang, L., Hunt, J., . . . Gowans, E. J. (1998). Exposure to GB virus type C or hepatitis G virus in selected Australian adult and children populations. Transfusion, 38(9), 821-827. Scopus27 WoS22 Europe PMC21 |
| 1998 | Selvey, L. A., Hyland, C. A., Mison, L., Solomon, N., & Gowans, E. J. (1998). Is there evidence for vector transmission of GBV-C?. Lancet, 351(9109), 1104-1105. Scopus6 WoS7 Europe PMC7 |
| 1997 | Harvey, T. J., Macnaughton, T. B., & Gowans, E. J. (1997). The development and characterisation of a SV40 T-antigen positive cell line of human hepatic origin. Journal of Virological Methods, 65(1), 67-74. Scopus9 WoS7 Europe PMC6 |
| 1997 | Wang, Y. H., Trowbridge, R., & Gowans, E. J. (1997). Expression and interaction of the hepatitis C virus structural proteins and the 5' untranslated region in baculovirus infected cells. Archives of Virology, 142(11), 2211-2223. Scopus5 WoS5 Europe PMC4 |
| 1997 | Atkins, G., Qiao, M., Coombe, D., Gowans, E., & Ashman, L. (1997). Hepatitis B virus binding to leucocyte plasma membranes utilizes a different region of the preS1 domain to the hepatocyte receptor binding site and does not require receptors for opsonins.. Immunology and Cell Biology, 75(3), 259-266. Scopus3 WoS1 |
| 1996 | Beardsley, A., Gowans, E., Burrell, C., & Marmion, B. (1996). Enhanced amplification of hepatitis C virus (HCV) cDNA by PCR: Detection of HCV RNA in archival sera. Journal of Clinical Microbiology, 34(6), 1581-1582. Scopus2 WoS2 Europe PMC1 |
| 1996 | Gong, Y., Trowbridge, R., Macnaughton, T. B., Westaway, E. G., Shannon, A. D., & Gowans, E. J. (1996). Characterization of RNA synthesis during a one-step growth curve and of the replication mechanism of bovine viral diarrhoea virus. Journal of General Virology, 77(11), 2729-2736. Scopus75 WoS71 Europe PMC55 |
| 1996 | Trowbridge, R., Sloots, T. P., Buda, P., Faoagali, J., Hyland, C., Young, I., & Gowans, E. J. (1996). An ELISA for the detection of antibody to the core antigen of hepatitis C virus: Use in diagnosis and analysis of indeterminate samples. Journal of Hepatology, 24(5), 532-538. Scopus4 WoS6 Europe PMC5 |
| 1996 | Beard, M. R., MacNaughton, T. B., & Gowans, E. J. (1996). Identification and characterization of a hepatitis delta virus RNA transcriptional promoter. Journal of Virology, 70(8), 4986-4995. Scopus66 WoS62 Europe PMC53 |
| 1996 | Blight, K., Trowbridge, R., & Gowans, E. J. (1996). Absence of double-stranded replicative forms of HCV RNA in liver tissue from chronically infected patients. Journal of Viral Hepatitis, 3(1), 29-36. Scopus8 WoS8 Europe PMC5 |
| 1994 | Qiao, M., Macnaughton, T. B., & Gowans, E. J. (1994). Adsorption and penetration of hepatitis B virus in a nonpermissive cell line. Virology, 201(2), 356-363. Scopus40 WoS38 Europe PMC29 |
| 1994 | MENG, Z., XU, D., SUN, D., LU, H., COPLAND, J., LIU, C., . . . GOWANS, E. J. (1994). A study of primary‐ and re‐infection with hepatitis C virus in blood transfusion recipients. Journal of Gastroenterology and Hepatology, 9(3), 211-216. |
| 1994 | McGuinness, P. H., Bishop, G. A., McCaughan, G. W., Trowbridge, R., & Gowans, E. J. (1994). False detection of negative-strand hepatitis C virus RNA. Lancet, 343(8896), 551-552. Scopus68 WoS68 Europe PMC22 |
| 1994 | Beardsley, A. M., LaBrooy, J. T., Rozen, L., & Gowans, E. J. (1994). A comparison of hepatitis C virus (HCV) RNA and – antibody as markers of infection and predictors of infectivity. Australian and New Zealand Journal of Medicine, 24(2), 182-187. Scopus10 WoS9 Europe PMC4 |
| 1994 | MENG, Z., SUN, Y., SUN, D., LIU, C., COPLAND, J., & GOWANS, E. J. (1994). A dynamic study of viraemia in chronic hepatitis C infection. Journal of Gastroenterology and Hepatology, 9(3), 242-244. Scopus4 WoS4 Europe PMC3 |
| 1994 | Gowans, E. J., Blight, K., Arthur, J., & Higgins, G. D. (1994). Detection of virus nucleic acids by radioactive and nonisotopic in situ hybridization.. Methods in Molecular Biology Clifton N J, 33, 243-256. Scopus1 Europe PMC1 |
| 1994 | Gowans, E. J., Arthur, J., Blight, K., & Higgins, G. D. (1994). Application of in situ hybridization for the detection of virus nucleic acids.. Methods in Molecular Biology Clifton N J, 33, 395-408. Scopus1 Europe PMC1 |
| 1994 | Blight, K., Lesniewski, R. R., Labrooy, J. T., & Gowans, E. J. (1994). Detection and distribution of hepatitis C—specific antigens in naturally infected liver. Hepatology, 20(3), 553-557. Scopus39 WoS44 Europe PMC30 |
| 1993 | Gowans, E. J., & Bonino, F. (1993). Hepatitis delta virus pathogenicity.. Progress in Clinical and Biological Research, 382, 125-130. Scopus19 Europe PMC9 |
| 1993 | Blight, K., Lesniewski, R., LaBrooy, J., Trowbridge, R., & Gowans, E. (1993). Localisation of hepatitis C virus proteins in infected liver tissue by immunofluorescence. Gastroenterologia Japonica, 28(5 Supplement), 55-58. Scopus8 Europe PMC9 |
| 1993 | Cole, S. M., Macnaughton, T. B., & Gowans, E. J. (1993). Differential roles for HDAg-p24 and -p27 in HDV pathogenesis.. Progress in Clinical and Biological Research, 382, 131-138. Scopus7 Europe PMC5 |
| 1993 | Dammacco, F., Sansonno, D., Beardsley, A., & Gowans, E. J. (1993). Failure to detect hepatitis C virus (HCV) genome by polymerase chain reaction in human anti-HCV-positive intravenous immunoglobulins. Clinical and Experimental Immunology, 92(2), 205-210. Scopus9 WoS9 Europe PMC3 |
| 1993 | Blight, K., Rowland, R., De La Hall, P. M., Lesniewski, R. R., Trowbridge, R., LaBrooy, J. T., & Gowans, E. J. (1993). Immunohistochemical detection of the NS4 antigen of hepatitis C virus and its relation to histopathology. American Journal of Pathology, 143(6), 1568-1573. Scopus36 WoS36 Europe PMC21 |
| 1993 | Hardiman, R. P., Shaw, D. R., Brooy, J. T. L., Rozen, L., de Boer, W. B., Rowland, R., . . . Gowans, E. J. (1993). Chronic liver disease in asymptomatic hepatitis C antibody positive blood donors. Australian and New Zealand Journal of Medicine, 23(2), 176-180. Scopus12 WoS14 Europe PMC5 |
| 1993 | Macnaughton, T. B., Beard, M. R., Chao, M., Gowans, E. J., & Lai, M. M. C. (1993). Endogenous Promoters Can Direct the Transcription of Hepatitis Delta Virus RNA from a Recircularized cDNA Template. Virology, 196(2), 629-636. Scopus37 WoS34 Europe PMC27 |
| 1992 | Sumathy, S., Thyagarajan, S. P., Latif, R., Madanagopalan, N., Raguram, K., Rajasambandam, P., & Gowans, E. (1992). A dipstick immunobinding enzyme-linked immunosorbent assay for serodiagnosis of hepatitis B and delta virus infections. Journal of Virological Methods, 38(1), 145-152. Scopus11 WoS11 Europe PMC7 |
| 1992 | Gowans, E. J. (1992). Autoradiographic detection of radiolabelled probes by in situ hybridizaiton. Liver, 12(4), 238-242. Scopus3 WoS3 Europe PMC2 |
| 1992 | Bilght, K., Trowbridge, R., Rewland, R., & Gowans, E. (1992). Detection of hepatitis C virus RNA by in situ hybridizaiton. Liver, 12(4), 286-289. Scopus35 WoS39 Europe PMC23 |
| 1992 | Qiao, M., Gowans, E. J., & Burrell, C. J. (1992). Intracellular factors, but not virus receptor levels, influence the age-related outcome of DHBV infection of ducks. Virology, 186(2), 517-523. Scopus10 WoS10 Europe PMC7 |
| 1992 | BEARDSLEY, A. M., BLIGHT, K., GOWANS, E. J., LABROOY, J. T., ROZEN, L., & BURRELL, C. J. (1992). HEPATITIS-C VIRUS-INFECTION IN BLOOD-DONORS - EVIDENCE FOR 2 GROUPS OF ANTI-HCV-POSITIVE INDIVIDUALS. HEPATOLOGY, 16(2), 515. |
| 1991 | MacNaughton, T. B., Gowans, E. J., McNamara, S. P., & Burrell, C. J. (1991). Hepatitis δ antigen is necessary for access of hepatitis s virus rna to the cell transcriptional machinery but is not part of the transcriptional complex. Virology, 184(1), 387-390. Scopus80 WoS83 Europe PMC66 |
| 1991 | Gaughwin, M. D., Gowans, E., Ali, R., & Burrell, C. (1991). Bloody needles: The volumes of blood transferred in simulations of needlestick injuries and shared use of syringes for injection of intravenous drugs. AIDS, 5(8), 1025-1027. Scopus47 WoS51 Europe PMC26 |
| 1991 | Cole, S. M., Gowans, E. J., Macnaughton, T. B., De La M. Hall, P., & Burrell, C. J. (1991). Direct evidence for cytotoxicity associated with expression of hepatitis delta virus antigen. Hepatology, 13(5), 845-851. Scopus76 WoS57 Europe PMC49 |
| 1990 | Qiao, M., Gowans, E. J., Bailey, S. E., Jilbert, A. R., & Burrell, C. J. (1990). Serological analysis of duck hepatitis B virus infection. Virus Research, 17(1), 3-13. Scopus15 WoS16 Europe PMC11 |
| 1990 | Gowans, E. J., Macnaughton, T. B., Mickan, L., Jilbert, A. R., & Burrell, C. J. (1990). Use of recombinant hepatitis delta antigen in diagnostic assays for HDV antibody. Journal of Virological Methods, 27(1), 69-78. Scopus5 WoS4 Europe PMC4 |
| 1990 | Macnaughton, T. B., Gowans, E. J., Reinboth, B., Jilbert, A. R., & Burrell, C. J. (1990). Stable expression of hepatitis delta virus antigen in a eukaryotic cell line. Journal of General Virology, 71(6), 1339-1345. Scopus40 WoS41 Europe PMC33 |
| 1990 | Macnaughton, T. B., Gowans, E. J., Albert, A. R., & Burrell, C. J. (1990). Hepatitis delta virus RNA, protein synthesis and associated cytotoxicity in a stably transfected cell line. Virology, 177(2), 692-698. Scopus65 WoS66 Europe PMC55 |
| 1990 | Niu, J., Wang, Y., Qiao, M., Gowans, E., Edwards, P., Thyagarajan, S. P., . . . Locarnini, S. (1990). Effect of Phyllanthus amarus on duck hepatitis B virus replication in vivo. Journal of Medical Virology, 32(4), 212-218. Scopus29 Europe PMC20 |
| 1990 | Gowans, E. J., Macnaughton, T. B., & Burrel, C. J. (1990). Hepatitis delta virus. Today S Life Science, 2(9), 48-54. |
| 1988 | Freiman, J. S., Jilbert, A. R., Dixon, R. J., Holmes, M., Gowans, E. J., Burrell, C. J., . . . Cossart, Y. E. (1988). Experimental duck hepatitis B virus infection: Pathology and evolution of hepatic and extrahepatic infection. Hepatology, 8(3), 507-513. Scopus61 WoS61 Europe PMC48 |
| 1988 | FREIMAN, J. S., JILBERT, A. R., BURRELL, C. J., HOLMES, M., GOWANS, E. J., HALL, P., & COSSART, Y. E. (1988). EARLY VIRUS-CELL INTERACTIONS IN HEPADNAVIRUS INFECTION. AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 18(3), 413. |
| 1988 | Jilbert, A. R., Freiman, J. S., Burrell, C. J., Holmes, M., Gowans, E. J., Rowland, R., . . . Cossart, Y. E. (1988). Virus-liver cell interactions in duck hepatitis B virus infection. A study of virus dissemination within the liver. Gastroenterology, 95(5), 1375-1382. Scopus38 WoS33 Europe PMC27 |
| 1988 | Gowans, E. J., Baroudy, B. M., Negro, F., Ponzetto, A., Purcell, R. H., & Gerin, J. L. (1988). Evidence for replication of hepatitis delta virus RNA in hepatocyte nuclei after in vivo infection. Virology, 167(1), 274-278. Scopus52 WoS52 Europe PMC46 |
| 1988 | Korba, B. E., Gowans, E. J., Wells, F. V., Tennant, B. C., Clarke, R., & Gerin, J. L. (1988). Systemic distribution of woodchuck hepatitis virus in the tissues of experimentally infected woodchucks. Virology, 165(1), 172-181. Scopus41 WoS43 Europe PMC34 |
| 1988 | Gowans, E. J. (1988). Strategies for in situ hybridization. La Ricerca in Clinica E in Laboratorio, 18(2-3), 171-176. Scopus1 |
| 1988 | LAWSON, M. J., FOCK, K. M., GOWANS, E. J., MATHEW, T. H., & BURRELL, C. J. (1988). Hepatitis B in renal transplant recipients: An assessment of the relationship of viral replication to liver pathology. Journal of Gastroenterology and Hepatology, 3(1), 47-53. Scopus2 WoS2 |
| 1987 | Taylor, J., Mason, W., Summers, J., Goldberg, J., Aldrich, C., Coates, L., . . . Gowans, E. (1987). Replication of human hepatitis delta virus in primary cultures of woodchuck hepatocytes. Journal of Virology, 61(9), 2891-2895. Scopus101 WoS110 Europe PMC78 |
| 1987 | JILBERT, A. R., FREIMAN, J. S., BURRELL, C. J., HOLMES, M., GOWANS, E. J., ROWLAND, R., . . . COSSART, Y. E. (1987). VIRUS-CELL INTERACTIONS IN DUCK HEPATITIS-B VIRUS-INFECTION OF PEKIN-AYLESBURY DUCKS - AN INSITU STUDY OF DHBV DNA, RNA, AND DHBSAG. JOURNAL OF MEDICAL VIROLOGY, 21(4), A75-A76. |
| 1987 | FREIMAN, J., JILBERT, A., HOLMES, M., GOWANS, E., BURRELL, C., & COSSART, Y. (1987). DUCK HEPATITIS-B VIRUS - SEQUENCE AND SIGNIFICANCE OF LYMPHOID SYSTEM INFECTION. JOURNAL OF MEDICAL VIROLOGY, 21(4), A75. |
| 1987 | Jilbert, A. R., Freiman, J. S., Gowans, E. J., Holmes, M., Cossart, Y. E., & Burrell, C. J. (1987). Duck hepatitis B virus DNA in liver, spleen, and pancreas: Analysis by in situ and southern blot hybridization. Virology, 158(2), 330-338. Scopus62 WoS56 Europe PMC48 |
| 1986 | Jilbert, A. R., Hertzog, P. J., Burrell, C. J., Gowans, E. J., Linnane, A. W., & Marmion, B. P. (1986). Production of a monoclonal antibody to human interferon-α (IFN-α) and its use to identify IFN-α-producing cells in virus infection in vivo. Microbial Pathogenesis, 1(2), 159-168. Scopus25 WoS29 Europe PMC22 |
| 1986 | Jilbert, A. R., Burrell, C. J., Gowans, E. J., Hertzog, P. J., Linnane, A. W., & Marmion, B. P. (1986). Cellular localization of α‐interferon in hepatitis B virus‐infected liver tissue. Hepatology, 6(5), 957-961. Scopus44 WoS42 Europe PMC31 |
| 1986 | LAWSON, M. J., FOCK, K. M., GOWANS, E., MATHEW, T., & BURRELL, C. J. (1986). HEPATITIS-B IN RENAL-TRANSPLANT RECIPIENTS - AN ASSESSMENT OF THE RELATIONSHIP OF VIRAL REPLICATION TO LIVER PATHOLOGY. AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 16(4), 597. |
| 1986 | Jilbert, A. R., Burrell, C. J., Gowans, E. J., & Rowland, R. (1986). Histological aspects of in situ hybridization - Detection of poly(A) nucleotide sequences in mouse liver sections as a model system. Histochemistry, 85(6), 505-514. Scopus20 WoS24 Europe PMC17 |
| 1986 | Gowans, E. J. (1986). Relationship between HBeAg and HBV DNA in patients with acute and persistent hepatitis B infection. Medical Journal of Australia, 145(9), 439-441. Scopus20 WoS21 Europe PMC14 |
| 1985 | Gowans, E. J., Burrell, C. J., Jilbert, A. R., & Marmion, B. P. (1985). Cytoplasmic (But not nuclear) hepatitis b virus (hbv) core antigen reflects hbv dna synthesis at the level of the infected hepatocyte. Intervirology, 24(4), 220-225. Scopus47 WoS46 Europe PMC40 |
| 1985 | Gowans, E. J., & Burrell, C. J. (1985). Widespread presence of cytoplasmic HBcAg in hepatitis B infected liver detected by improved immunochemical methods. Journal of Clinical Pathology, 38(4), 393-398. Scopus46 WoS48 Europe PMC37 |
| 1985 | Burrell, C. J., Gowans, E. J., & Marmion, B. P. (1985). HIGH LEVELS OF CYTOPLASMIC HEPATITIS B CORE ANTIGEN AS RELIABLE MARKER OF HBV DNA REPLICATION. Lancet, 325(8426), 454-455. Scopus9 WoS10 Europe PMC7 |
| 1984 | Burrell, C. J., Gowans, E. J., Rowland, R., Hall, P., Jilbert, A. R., & Marmion, B. P. (1984). Correlation Between Liver Histology and Markers of Hepatitis B Virus Replication in Infected Patients: A Study by In Situ Hybridization. Hepatology, 4(1), 20-24. Scopus57 WoS70 Europe PMC48 |
| 1983 | Gowans, E. J., Burrell, C. J., Jilbert, A. R., & Marmion, B. P. (1983). Patterns of single- and double-stranded hepatitis B virus DNA and viral antigen accumulation in infected liver cells. Journal of General Virology, 64(6), 1229-1239. Scopus38 |
| 1983 | GOWANS, E. J., BURRELL, C. J., JILBERT, A. R., & MARMION, B. P. (1983). PATTERNS OF SINGLE-STRANDED AND DOUBLE-STRANDED HEPATITIS-B VIRUS-DNA AND VIRAL-ANTIGEN ACCUMULATION IN INFECTED LIVER-CELLS. JOURNAL OF GENERAL VIROLOGY, 64(JUN), 1229-1239. WoS45 Europe PMC31 |
| 1982 | BURRELL, C. J., GOWANS, E. J., JILBERT, A. R., LAKE, J. R., & MARMION, B. P. (1982). HEPATITIS-B VIRUS-DNA DETECTION BY INSITU CYTOHYBRIDIZATION - IMPLICATIONS FOR VIRAL REPLICATION STRATEGY AND PATHOGENESIS OF CHRONIC HEPATITIS. HEPATOLOGY, 2(2), S85-S91. WoS38 |
| 1982 | Burrell, C., Gowans, E., & Jilbert, A. (1982). Hepatitis B virus DNA detection by in situ cytohybridization: Implications for viral replication strategy and pathogenesis of chronic hepatitis. Hepatology, 2(2 Suppl.). Scopus32 |
| 1981 | Gowans, E. J., Burrell, C. J., Jilbert, A. R., & Marmion, B. P. (1981). Detection of hepatitis B virus DNA sequences in infected hepatocytes by in situ cytohybridisation. Journal of Medical Virology, 8(1), 67-78. Scopus36 WoS38 Europe PMC27 |
| 1979 | GOWANS, E. J., & MCNULTY, M. S. (1979). NOVEL TUBULAR AND CRYSTALLINE-STRUCTURES IN PURIFIED PREPARATIONS OF NEWCASTLE-DISEASE VIRUS. ARCHIVES OF VIROLOGY, 62(4), 353-356. |
| 1977 | MCNULTY, M. S., GOWANS, E. J., LOUZA, A. C., & FRASER, G. (1977). ELECTRON-MICROSCOPIC STUDY OF MDBK CELLS PERSISTENTLY INFECTED WITH NEWCASTLE-DISEASE VIRUS. ARCHIVES OF VIROLOGY, 53(3), 185-195. WoS6 Europe PMC3 |
| 1975 | MCNULTY, M. S., GOWANS, E. J., HOUSTON, M. J., & FRASER, G. (1975). NEURAMINIDASE CONTENT OF STRAINS OF NEWCASTLE-DISEASE VIRUS WHICH DIFFER IN VIRULENCE. JOURNAL OF GENERAL VIROLOGY, 27(JUN), 309-402. WoS8 |
| 1973 | GOWANS, E. J. (1973). IMPROVED METHOD OF AGAR PELLETED CELLS FOR ELECTRON-MICROSCOPY. MEDICAL LABORATORY TECHNOLOGY, 30(2), 113-115. WoS5 Europe PMC6 |
| Year | Citation |
|---|---|
| 2017 | Tomusange, K., Wijesundara, D., Gowans, E., & Grubor-Bauk, B. (2017). Human rhinovirus-A1 as an expression vector. In M. C. Ferran, & G. R. Skuse (Eds.), Recombinant Virus Vaccines: Methods and Protocols (Vol. 1581, pp. 181-201). UK: Humana Press. DOI |
| 2000 | Burrell, C., Chisari, F., Gerlich, W., Gowans, E., Howard, C., Kann, M., & Marion, P. (2000). Taxomic Structure of the Family. In M. van Regenmortel, C. Fauquet, & D. Bishop (Eds.), Virus Taxonomy Classification and Nomenclature of Viruses (7 ed., pp. 325-334). San Diego, USA: Academic Press. |
| Year | Citation |
|---|---|
| 2013 | Torresi, J., Chin, R., Chua, B., Johnson, D., Earnest-Sliveira, L., Zeng, W., . . . Jackson, D. C. (2013). HEPATITIS C VLPS DELIVERED TO DENDRITIC CELLS BY A TLR2 TARGETING LIPOPEPTIDE RESULTS IN ENHANCED NEUTRALIZING ANTIBODY AND CELL-MEDIATED RESPONSES. In JOURNAL OF HEPATOLOGY Vol. 58 (pp. S496-S497). Amsterdam, NETHERLANDS: ELSEVIER SCIENCE BV. DOI |
| 2008 | Gowans, E. J., Jones, K. L., Latour, P. A., Chua, B. Y., Dinatale, I., Loudovaris, M., . . . Jackson, D. C. (2008). DENDRITIC CELL IMMUNOTHERAPY TO TREAT PATIENTS WITH PERSISTENT HCV INFECTION. In HEPATOLOGY Vol. 48 (pp. 1013A). San Francisco, CA: JOHN WILEY & SONS INC. |
| 2006 | Woollard, D. J., Haqshenas, G., Dong, X., & Gowans, E. J. (2006). Detection of intrahepatic virus-specific T-cells in marmosets with resolved GBV-B infection. In JOURNAL OF CLINICAL VIROLOGY Vol. 36 (pp. S16). Paris, FRANCE: ELSEVIER SCIENCE BV. DOI |
| 2005 | Woollard, D. J., Martyn, J. C., Lee, M. L., Jones, K. L., Ffrench, R. A., & Gowans, E. J. (2005). Investigation of a novel HCV recombinant baculovirus as a vaccine delivery system. In TISSUE ANTIGENS Vol. 66 (pp. 592-593). Melbourne, AUSTRALIA: BLACKWELL PUBLISHING. |
| 2002 | Whiting, P. W., Gowans, E. J., Sloots, T. P., Mackay, I. M., Tillack, S., Harrison, M., . . . Crawford, D. H. G. (2002). The effects of vitamin B12 on hepatitis C virus replication. In GASTROENTEROLOGY Vol. 123 (pp. 74). W B SAUNDERS CO. |
| 2000 | Crawford, D. H., Lott, W. B., Cooksley, G., HArrison, M., McDonald, G., Sloots, T., & Gowans, E. J. (2000). Effects of cobalamin on hepatitis C virus translation and replication.. In HEPATOLOGY Vol. 32 (pp. 359A). W B SAUNDERS CO. |
| 1993 | ATKINS, G. J., GOWANS, E. J., & ASHMAN, L. K. (1993). HEPATITIS-B VIRUS RECEPTORS ON HEMATOPOIETIC-CELLS. In JOURNAL OF LEUKOCYTE BIOLOGY (pp. 46). FEDERATION AMER SOC EXP BIOL. |
| 1991 | MACNAUGHTON, T. B., GOWANS, E. J., QIAO, M., & BURRELL, C. J. (1991). SIMULTANEOUS EXPRESSION FROM CDNA OF MARKERS OF HEPATITIS-DELTA VIRUS AND HEPADNAVIRUS INFECTION IN CONTINUOUS CELL-LINES. In F. B. Hollinger, S. M. Lemon, & H. Margolis (Eds.), VIRAL HEPATITIS AND LIVER DISEASE (pp. 465-468). HOUSTON, TX: WILLIAMS & WILKINS. WoS2 |
| 1991 | Jilbert, A. R., Gowans, E. J., Macnaughton, T. B., & Burrell, C. J. (1991). Characterization of a subgenomic HDV-specific poly(A)+ RNA species isolated from human hepatoma cells supporting HDV RNA replication.. In J. L. GERIN, R. H. PURCELL, & M. RIZZETTO (Eds.), Progress in Clinical and Biological Research Vol. 364 (pp. 309-314). WASHINGTON, DC: WILEY-LISS, INC. Scopus6 WoS7 Europe PMC4 |
| 1991 | Gowans, E. J., Macnaughton, T. B., Jilbert, A. R., & Burrell, C. J. (1991). Cell culture model systems to study HDV expression, replication and pathogenesis.. In J. L. GERIN, R. H. PURCELL, & M. RIZZETTO (Eds.), Progress in Clinical and Biological Research Vol. 364 (pp. 299-308). WASHINGTON, DC: WILEY-LISS, INC. Scopus9 WoS9 Europe PMC5 |
| 1987 | GOWANS, E. J., BAROUDY, B. M., KORBA, B. E., & GERIN, J. L. (1987). MOLECULAR MARKERS OF WHV AND HDV INFECTION AT THE LEVEL OF THE SINGLE CELL. In JOURNAL OF CELLULAR BIOCHEMISTRY (pp. 23). WILEY-LISS. |
| 1987 | NEGRO, F., GOWANS, E., WELLS, F., HOOFNAGLE, J., BONINO, F., BAROUDY, B., & GERIN, J. (1987). AN INSITU HYBRIDIZATION ASSAY FOR HEPATITIS-DELTA-VIRUS (HDV) RNA IN LIVER AND ITS CLINICAL UTILITY AS A MARKER OF HDV REPLICATION. In JOURNAL OF HEPATOLOGY Vol. 5 (pp. S48). MUNKSGAARD INT PUBL LTD. WoS2 |
| 1987 | KORBA, B., TENNANT, B., GOWANS, E., WELLS, F., CLARKE, R., & GERIN, J. (1987). INFECTION AND TISSUE TROPISM OF WHV DURING THE NATURAL COURSE OF EXPERIMENTAL VIRAL-INFECTION OF WOODCHUCKS. In JOURNAL OF CELLULAR BIOCHEMISTRY (pp. 24). WILEY-LISS. |
| 1987 | BAROUDY, B. M., FUERST, T. R., GOWANS, E. J., BRANCH, A. D., ROBERTSON, H. D., WELLS, F. V., . . . GERIN, J. L. (1987). MOLECULAR-BIOLOGY OF HEPATITIS-D VIRUS. In JOURNAL OF MEDICAL VIROLOGY Vol. 21 (pp. A35). WILEY-LISS. WoS1 |
| Year | Citation |
|---|---|
| 2017 | Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2017). Novel DNA vaccine formulations encoding secreted HCV-E1/E2 fused to the IMX313 oligomerisation domain are immunogenic in mice. Poster session presented at the meeting of 12th Annual Scientific Meeting of the Australian Centre for HIV and Hepatitis Virology. |
| 2017 | Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2017). Novel DNA vaccine formulations encoding secreted HCV-E1/E2 fused to the IMX313 oligomerisation domain are immunogenic in mice. Poster session presented at the meeting of Adelaide Immunology Retreat. Nuriootpa. |
| 2017 | Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2017). Novel DNA vaccine formulations encoding secreted HCV-E1/E2 fused to the IMX313 oligomerisation domain are immunogenic in mice. Poster session presented at the meeting of Florey Postgraduate Research Conference. |
| 2017 | Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2017). Enhancing the immunogenicity of HCV vaccines by fusing E1/E2 to the IMX313P multimerization technology. Poster session presented at the meeting of 24th International Symposium on Hepatitis C Virus and Related Viruses. Hyannis, Cape Cod, Massachusetts, USA. |
| 2017 | Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2017). Novel DNA vaccines encoding secreted HCV-E1/E2 fused to the IMX313 oligomerisation domain are immunogenic in mice. Poster session presented at the meeting of The Queen Elizabeth Hospital (TQEH) Research Day. Adeleide, Australia. |
| 2017 | Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2017). Enhancing the immunogenicity of HCV vaccines by fusing E1/E2 to the IMX313P oligomerisation technology. Poster session presented at the meeting of 9th Australasian Virology Society Meeting. |
| 2016 | Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2016). A novel DNA-based virus-like particle (VLP) vaccine against hepatitis C.. Poster session presented at the meeting of Florey Postgraduate Research Conference. |
| 2016 | Masavuli, M. G., Wijesundara, D. W., Grubor-Bauk, B., & Gowans, E. J. (2016). A DNA-based virus-like particle (VLP) vaccine against the hepatitis C virus. Poster session presented at the meeting of The Queen Elizabeth Hospital (TQEH) Research Day. Adelaide. |
| 2016 | Tomusange, K., Wijesundara, D., Gummow, J., Gowans, E. J., & Grubor-Bauk, B. (2016). Mucosal vaccination with a live recombinant rhinovirus followed by intradermal DNA administration elicits protective HIV-specific immune responses. Poster session presented at the meeting of Abstracts of the 2016 Conference on HIV Research for Prevention (HIV R4P), as published in Aids Research and Human Retroviruses. Chicago, IL: Mary Ann Liebert. DOI |
| 2015 | Masavuli, M. G., Grubor-Bauk, B. G., Wijesundara, D. K., & Gowans, E. J. (2015). A novel DNA-based virus-like particle (VLP) vaccine for hepatitis C virus. Poster session presented at the meeting of Florey Postgraduate Research Conference. AdelaIide. |
| 2015 | Masavuli, M. G., Wijesundara, D. K., grubor-bauk, B., & gowans, E. G. (2015). A novel DNA-based virus-like particle vaccine for hepatitis C virus. Poster session presented at the meeting of The Queen Elizabeth Hospital (TQEH) Research Day 2015. Adelaide. |
| 2013 | Loveland, B. E., Latour, P., Roberts, S. K., Gordon, A., Kemp, W., Kitson, M., . . . Gowans, E. J. (2013). A Phase I clinical trial of cellular immunotherapy for persistent Hepatitis C infection. Poster session presented at the meeting of Clinical and Experimental Pharmacology and Physiology. Hangzhou, Peoples Republic of China: Wiley-Blackwell. |
| Year | Citation |
|---|---|
| 2018 | Masavuli, M. G. (2018). Novel DNA Vaccine Formulations Against Hepatitis C Virus. (PhD Thesis). |
Grants and Funding
| 2009-2011 | A novel HCV vaccine |
EJ Gowans, B Loveland |
NHMRC |
$151,000 pa |
| 2009-2011 | A new HCV cell therapy |
EJ Gowans, SK Roberts, B Loveland |
NHMRC |
$164,749 pa |
| 2008-2009 | A replication defective vaccine strategy for HCV. |
EJ Gowans, B Loveland, J Torresi, S Li |
ACH2 | $110,000 pa |
| 2011-13 | A vaccine for hepatitis C virus. |
EJ Gowans, J Torresi, S Das |
Australia-India Biotechnology Fund | $100,000 pa |
| 2012-2014 | Mucosal immunity to HIV |
EJ Gowans, A Suhrbier, S Wesselingh |
NHMRC | $188,000 pa |
| 2012-13 | Development of a cytolytic HCV vaccine and a novel challenge model to test efficacy | E J Gowans, B Grubor-Bauk | ACH2 | $174,000 |
| 2014-15 | DNA vaccine therapy for HCV | E J Gowans, I Roberts-Thomson, B Grubor-Bauk | THRF | $300,000 |
| 2014 | Optimisation of HCV vaccine design | E J Gowans, B Grubor-Bauk | THRF | $100,000 |
| 2014-16 | A quadrivalent vaccine for hepatitis C | Joseph Torresi, E J Gowans | NHMRC | $450,000 |
| 2015-16 | Approaches to develop an effective HCV vaccine | E J Gowans, J Torresi, S Das | AISRF | $200,000 |
| 2016-17 | A DNA vaccine to induce protective neutralizing antibodies to the HIV Tat protein | E J Gowans | THRF | $160,000 |
| 2017 | A multigenotypic HCV DNA vaccine | E J Gowans, B Grubor-Bauk, D Wijesundara | ACH2 | $85,000 |
| 2016-2018 | A DNA vaccine for Zika virus |
E J Gowans, B Grubor-Bauk, D Wijesundara |
NFMRI | $293,880 |
Teaching and Supervision
| 1964 - 1969 | Preparation of materials for medical and science student practical classes and for the preparation of demonstrations. |
| 1972 - 1975 | Part-time demonstrator and tutor, Napier College, Edinburgh, to teach Medical Microbiology in the Higher National Certificate Course. |
| 1984 - 1988 | Lecturer and demonstrator in Virology teaching programme provided by the Division of Medical Virology, IMVS, to Science, Dental and Medical Students in the University of Adelaide. |
| 1988 - 1993 | Formal appointment as Visiting Lecturer, Department of Microbiology and Immunology, University of Adelaide. Responsible for organisation of Virology Honours course. |
| 1994-1997 | Honorary Reader, Department of Microbiology, University of Queensland. |
| 1996-2002 | Assoc. Professor, Department of Paediatrics, University of Queensland. |
| 1997-2002 | Adjunct Professor, Department of Microbiology, University of Queensland. |
| 2003-2012 | Honorary Professor, Dept of Microbiology, Monash University |
| 2009- | Honorary Professor, University of Adelaide. |
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2015 - 2016 | Principal Supervisor | Strategies for the development of recombinant porcine adenovirus-based vaccines against Hepatitis C virus. | Master of Philosophy (Medical Science) | Master | Full Time | Mr Harshwardhan Jagdale |
| 2015 - 2019 | Principal Supervisor | Pre-Clinical Evaluation of a Vaccination Strategy to Induce Liver Resident Memory T Cells against Hepatitis C Virus | Doctor of Philosophy | Doctorate | Full Time | Mr Zelalem Addis Mekonnen |
| 2014 - 2018 | Principal Supervisor | Novel DNA Vaccine Formulations Against Hepatitis C Virus | Doctor of Philosophy | Doctorate | Full Time | Dr Makutiro Ghislain Masavuli |
| 2013 - 2016 | Principal Supervisor | Novel Recombinant DNA and Live Virus Vaccines to Prevent or Control HIV-1 Infection | Doctor of Philosophy | Doctorate | Full Time | Mr Khamis Tomusange |
| 2012 - 2014 | Principal Supervisor | Evaluating the Immuno-modulatory Effects of a Natural Adjuvant as a Novel Vaccine Strategy | Doctor of Philosophy | Doctorate | Full Time | Miss Tasmin Garrod |
| 2012 - 2013 | Principal Supervisor | Optimising DNA vaccine technology to prevent HIV-1 Infection | Doctor of Philosophy | Doctorate | Full Time | Miss Tessa Gargett |
| 2012 - 2017 | Principal Supervisor | The Development of a Multi-Antigenic Cytolytic DNA Vaccine against HCV | Doctor of Philosophy | Doctorate | Full Time | Dr Jason Anthony Gummow |
| 2010 - 2012 | Principal Supervisor | Suicide Genes in a Novel Vaccination Strategy for Hepatitis C | Master of Philosophy | Master | Full Time | Mr Hugh Francis Trahair |
| Date | Role | Committee | Institution | Country |
|---|---|---|---|---|
| 2015 - ongoing | Member | NHMRC Grant Assigner’s Panel | - | - |
| 2012 - ongoing | Chair | Strategic Research Directions Committee | Basil Hetzel Institute, The Queen Elizabeth Hospital | - |
| 2012 - ongoing | Member | BHI Policy Committee | - | - |
| 2012 - ongoing | Member | Local organising committee | Australian-Pacific Congress of Virology | - |
| 2012 - ongoing | Member | Microbiology Grant Review Panel | NHMRC | - |
| 2012 - 2014 | Member | Advisory Committee for Biologicals, Therapeutic Goods Administration | - | - |
| 2005 - ongoing | Chair | Institutional Biosafety Committee | The Queen Elizabeth Hospital and Basil Hetzel Institute | Australia |
| Date | Role | Membership | Country |
|---|---|---|---|
| 2014 - ongoing | - | Virus Research | - |
| 1999 - ongoing | - | Journal of Gastroenterology and Hepatology | - |
| 1998 - ongoing | - | Virus Genes | - |
| Date | Institution | Department | Organisation Type | Country |
|---|---|---|---|---|
| 2012 - ongoing | Viralytics Ltd | - | - | - |
