My PhD works focuses on delineating the cell pathology of Gaucher disease (GD), a rare inborn error of sphingolipid catabolism, characterised by both visceral disease (organ enlargement, bone disease) and severe neurologic decline (childhood dementia). My research involve the use of liquid chromatography-tandem mass spectrometry and stable isotope labelling techniques to explore the sphingolipid profiles of different GD cell types. This approach clarifies sphingolipid dyshomeostasis at a cellular level for a better understanding of how different cells respond to stress and contribute to overall disease. 

My broader research interests include neurodegenerative disease, lipid metabolism, and neuroinflammation.