Richard D'Andrea

Prof Richard D'Andrea

Professor of Leukaemia Biology

Centre for Cancer Biology

College of Health

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

I am head of the Acute Leukaemia Laboratory at the Centre for Cancer Biology (UniSA), have extensive expertise in leukaemia biology, research leadership experience, and established clinical and industry networks. I have been a Program Leader at the Women’s and Children’s Health Research Institute and Chief Medical Scientist (Haematology/Oncology) at the Queen Elizabeth Hospital. I have held the Australian Research Council QEII Fellowship and the Peter Nelson Leukaemia Fellowship. My standing in the field of blood cancers is evident from >70 publications and my involvement in clinical trials and national and international studies on AML.

Year Citation
2024 Hong, L. E., Wechalekar, M. D., Kutyna, M. M., Small, A., Lim, K., Thompson-Peach, C. A., . . . Hiwase, D. K. (2024). IDH-Mutant Myeloid Neoplasms are Associated with Seronegative Rheumatoid Arthritis and Innate Immune Activation. Blood, 143(18), 1873-1877.
DOI Scopus11 WoS11 Europe PMC10
2024 Hassan, N., Yi, H., Malik, B., Gaspard-Boulinc, L., Samaraweera, S. E., Casolari, D. A., . . . Wang, J. Y. (2024). Loss of the stress sensor GADD45A promotes stem cell activity and ferroptosis resistance in LGR4/HOXA9-dependent AML. Blood, 144(1), 84-98.
DOI Scopus12 WoS12 Europe PMC12
2023 Conn, V. M., Gabryelska, M., Toubia, J., Kirk, K., Gantley, L., Powell, J. A., . . . Conn, S. J. (2023). Circular RNAs drive oncogenic chromosomal translocations within the MLL recombinome in leukemia. Cancer Cell, 41(7), 1309-1326.e10.
DOI Scopus51 WoS50 Europe PMC47
2023 Sebastian, S., Hoffmann, M. K., Howard, D., Young, C., Washington, J., Unterweger, H., . . . Kempson, I. (2023). Kinetic effects of transferrin-conjugated gold nanoparticles on the antioxidant glutathione-thioredoxin pathway. Antioxidants, 12(8, article no. 1617), 1-21.
DOI Scopus8 WoS8 Europe PMC7
2023 Samaraweera, S. E., Geukens, T., Casolari, D. A., Nguyen, T., Sun, C., Bailey, S., . . . Ross, D. M. (2023). Novel modes of MPL activation in triple-negative myeloproliferative neoplasms. Pathology, 55(1), 77-85.
DOI Scopus2 WoS2 Europe PMC2
2023 Kan, W. L., Dhagat, U., Hercus, T. R., Kaufmann, K. B., Nero, T. L., Zeng, A. G. X., . . . Lopez, A. (2023). Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia. Cancer Discovery, 13(8), 1922-1947.
DOI Scopus9 WoS8 Europe PMC9
2022 Lewis, A. C., Pope, V. S., Tea, M. N., Li, M., Nwosu, G. O., Nguyen, T. M., . . . Pitson, S. M. (2022). Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia.. Blood, 139(26), 3737-3751.
DOI Scopus37 WoS32 Europe PMC35
2022 Bassal, M. A., Samaraweera, S. E., Lim, K., Bernard, B. A., Bailey, S., Kaur, S., . . . D'Andrea, R. J. (2022). Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia. Nature Communications, 13(1), 1-12.
DOI Scopus18 WoS19 Europe PMC16
2021 Singhal, D., Hahn, C. N., Feurstein, S., Wee, L. Y. A., Moma, L., Kutyna, M. M., . . . Hiwase, D. K. (2021). Targeted gene panels identify a high frequency of pathogenic germline variants in patients diagnosed with a hematological malignancy and at least one other independent cancer. Leukemia, 35(11), 3245-3256.
DOI Scopus48 WoS46 Europe PMC44
2021 Yusenko, M. V., Trentmann, A., Casolari, D. A., Abdel Ghani, L., Lenz, M., Horn, M., . . . Klempnauer, K. H. (2021). C/EBPβ is a MYB- and p300-cooperating pro-leukemogenic factor and promising drug target in acute myeloid leukemia. Oncogene, 40(29), 4746-4758.
DOI Scopus20 WoS16 Europe PMC14
2021 Samaraweera, S. E., Wang, P. P. S., Li, K. L., Casolari, D. A., Feng, J., Maung, K. Z. Y., . . . D'Andrea, R. J. (2021). Childhood acute myeloid leukemia shows a high level of germline predisposition. Blood, 138(22), 2293-2298.
DOI Scopus11 WoS9 Europe PMC9
2021 Rapaport, F., Neelamraju, Y., Baslan, T., Hassane, D., D'Andrea, R., & Garrett Bakelman, F. E. (2021). Genomic and evolutionary portraits of disease relapse in acute myeloid leukemia. Leukemia, 35(9), 2688-2692.
DOI Scopus12 Europe PMC12
2020 Austin, R. J., Straube, J., Bruedigam, C., Pali, G., D'Andrea, R., & Lane, S. W. (2020). Distinct effects of ruxolitinib and interferon-alpha on murine JAK2V617F myeloproliferative neoplasm hematopoietic stem cell populations. Leukemia, 34(4), 1075-1089.
DOI Scopus48 WoS45 Europe PMC42
2020 McCalmont, H., Li, K. L., Jones, L., Toubia, J., Bray, S. C., Casolari, D. A., . . . D'Andrea, R. J. (2020). Efficacy of combined CDK9/13ET inhibition in preclinical models of MLL-rearranged acute leukemia. Blood Advances, 4(2), 296-300.
DOI Scopus23 WoS22 Europe PMC24
2020 Brown, A. L., Arts, P., Carmichael, C. L., Babic, M., Dobbins, J., Chong, C. -E., . . . Scott, H. S. (2020). RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML. Blood Advances, 4(6), 1131-1144.
DOI Scopus131 WoS117 Europe PMC106
2020 Salik, B., Yi, H., Hassan, N., Santiappillai, N., D'Andrea, R. J., & Wang, J. Y. (2020). Targeting RSPO3-LGR4 signaling for leukemia stem cell eradication in acute myeloid leukemia. Cancer cell, 38(2), 263.e6-278.e6.
DOI Scopus94 WoS87 Europe PMC86
2019 Chipurupalli, S., Kannan, E., Tergaonkar, V., D'Andrea, R., & Robinson, N. (2019). Hypoxia Induced ER Stress Response as an Adaptive Mechanism in Cancer. International journal of molecular sciences, 20(3), 1-17.
DOI Scopus108 WoS105 Europe PMC99
2019 Iacobucci, I., Wen, J., Meggendorfer, M., Choi, J. K., Shi, L., Pounds, S. B., . . . Mullighan, C. G. (2019). Genomic subtyping and therapeutic targeting of acute erythroleukemia. Nature genetics, 51(4), 694-704.
DOI Scopus122 WoS121 Europe PMC112
2019 Singhal, D., Wee, L. Y. A., Kutyna, M. M., Chhetri, R., Geoghegan, J., Schreiber, A. W., . . . Hiwase, D. K. (2019). The mutational burden of therapy-related myeloid neoplasms is similar to primary myelodysplastic syndrome but has a distinctive distribution. Leukemia, 33(12), 2842-2853.
DOI Scopus50 WoS48 Europe PMC44
2018 Beck, D., Thoms, J., Palu, C., Herold, T., Shah, A., Olivier, J., . . . Pimanda, J. (2018). A four-gene lincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patients. Leukemia, 32(2), 263-272.
DOI Scopus38 WoS37 Europe PMC29
2018 Chong, C. -E., Venugopal, P., Stokes, P., Lee, Y., Brautigan, P., Yeung, D., . . . Scott, H. (2018). Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes. Leukemia, 32(1), 194-202.
DOI Scopus56 WoS54 Europe PMC52
2018 Maung, K. Z. Y., Leo, P. J., Bassal, M., Casolari, D. A., Gray, J. X., Bray, S. C., . . . Gonda, T. J. (2018). Rare variants in Fanconi anemia genes are enriched in acute myeloid leukemia. Blood Cancer Journal, 8(6), 50-1-50-5.
DOI Scopus16 WoS16 Europe PMC13
2017 Venugopal, P., Moore, S., Lawrence, D., George, A., Hannan, R., Bray, S., . . . Scott, H. (2017). Self-reverting mutations partially correct the blood phenotype in a Diamond Blackfan Anemia patient. Haematologica, 102(12), e506-e509.
DOI Scopus29 WoS25 Europe PMC23
2017 Wittwer, N. L., Brumatti, G., Marchant, C., Sandow, J. J., Pudney, M. K., Dottore, M., . . . Ramshaw, H. S. (2017). High CD123 levels enhance proliferation in response to IL-3, but reduce chemotaxis by downregulating CXCR4 expression. Blood Advances, 1(15), 1067-1079.
DOI Scopus33 WoS31 Europe PMC25
2017 Powell, J., Lewis, A., Zhu, W., Toubia, J., Pitman, M., Wallington-Beddoe, C., . . . Pitson, S. (2017). Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia.. Blood, 129(6), 771-782.
DOI Scopus86 WoS80 Europe PMC74
2017 Sadras, T., Kok, C., Perugini, M., Ramshaw, H., & D'Andrea, R. (2017). miR-155 as a potential target of IL-3 signaling in primary AML cells. Leukemia Research, 57, 57-59.
DOI Scopus8 WoS7 Europe PMC6
2017 Casolari, D., Nguyen, T., Butcher, C., Iarossi, D., Hahn, C., Bray, S., . . . D'Andrea, R. (2017). A novel, somatic, transforming mutation in the extracellular domain of epidermal growth factor receptor identified in myeloproliferative neoplasm. Scientific Reports, 7(1), 2467-1-2467-9.
DOI Scopus6 WoS6 Europe PMC7
2017 Tiong, I., Casolari, D., Moore, S., Nguyen, T., Van Velzen, M., Zantomio, D., . . . Ross, D. (2017). Apparent ‘JAK2-negative’ polycythaemia vera due to compound mutations in exon 14. British Journal of Haematology, 178(2), 333-336.
DOI Scopus12 WoS11 Europe PMC10
2016 Shahrin, N., Diakiw, S., Dent, L., Brown, A., & D'Andrea, R. (2016). Conditional knockout mice demonstrate function of Klf5 as a myeloid transcription factor. Blood, 128(1), 55-59.
DOI Scopus28 WoS29 Europe PMC28
2016 Li, S., Garrett-Bakelman, F. E., Chung, S. S., Sanders, M. A., Hricik, T., Rapaport, F., . . . Mason, C. E. (2016). Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia. Nature Medicine, 22(7), 792-799.
DOI Scopus314 WoS303 Europe PMC301
2016 Tiong, I. S., Casolari, D. A., Nguyen, T., Van Velzen, M. J. M., Ambler, K., D'Andrea, R. J., & Ross, D. M. (2016). Masked polycythaemia vera is genetically intermediate between JAK2V617F mutated essential thrombocythaemia and overt polycythaemia vera. Blood cancer journal, 6(8), 1-3.
DOI Scopus5 WoS4 Europe PMC4
2016 Dawar, S., Shahrin, N., Sladojevic, N., D'Andrea, R., Dorstyn, L., Hiwase, D., & Kumar, S. (2016). Impaired haematopoietic stem cell differentiation and enhanced skewing towards myeloid progenitors in aged caspase-2-deficient mice. Cell Death and Disease, 7(12), e2509-1-e2509-9.
DOI Scopus26 WoS27 Europe PMC27
2016 Lewinsohn, M., Brown, A. L., Weinel, L. M., Phung, C., Rafidi, G., Lee, M. K., . . . Scott, H. S. (2016). Novel germ line DDX41 mutations define families with a lower age of MDS/AML onset and lymphoid malignancies. Blood, 127(8), 1017-1023.
DOI Scopus190 WoS188 Europe PMC160
2016 Lynch, J. R., Yi, H., Casolari, D. A., Voli, F., Gonzales-Aloy, E., Fung, T. K., . . . Wang, J. Y. (2016). Gaq signaling is required for the maintenance of MLL-AF9-induced acute myeloid leukemia. Leukemia, 30(8), 1745-1748.
DOI Scopus8 WoS7 Europe PMC7
2016 Sadras, T., D'Andrea, R., & White, D. (2016). The Role of Wnt/β -Catenin Signaling in Normal and Malignant Hematopoiesis, Hemostasis. J Blood Res Hematol Dis, 1(1), 1-9.
DOI
2015 Li, K. L., Bray, S. C., Iarossi, D., Adams, J., Zhong, L., Noll, B., . . . D'Andrea, R. J. (2015). Investigation of a novel cyclin-dependent-kinase (CDK) inhibitor Cdki-73 as an effective treatment option for MLL-AML. Blood, 126(23), 1365.
DOI WoS5
2015 Forristal, C. E., Brown, A. L., Helwani, F. M., Winkler, I. G., Nowlan, B., Barbier, V., . . . Levesque, J. P. (2015). Hypoxia inducible factor (HIF)-2α accelerates disease progression in mouse models of leukemia and lymphoma but is not a poor prognosis factor in human AML. Leukemia, 29(10), 2075-2085.
DOI Scopus34 WoS34 Europe PMC37
2015 Hahn, C., Ross, D., Feng, J., Beligaswatte, A., Hiwase, D., Parker, W., . . . Scott, H. (2015). A tale of two siblings: two cases of AML arising from a single pre-leukemic DNMT3A mutant clone. Leukemia, 29(10), 2101-2104.
DOI Scopus29 WoS26 Europe PMC28
2014 Li, S., Garrett-Bakelman, F., Perl, A., Luger, S., Zhang, C., To, B., . . . Mason, C. (2014). Dynamic evolution of clonal epialleles revealed by methclone. Genome Biology, 15(9), 472-1-472-12.
DOI Scopus56 WoS76 Europe PMC59
2014 Tan, P., Wei, A., Mithraprabhu, S., Cummings, N., Liu, H., Perugini, M., . . . Spencer, A. (2014). Dual epigenetic targeting with panobinostat and azacitidine in acute myeloid leukemia and high-risk myelodysplastic syndrome. Blood Cancer Journal, 4(1), e170-1-e170-8.
DOI Scopus91 WoS85 Europe PMC76
2014 Perugini, M., Samaraweera, S. E., Brown, A. L., Cummings, N., Danner, S., Tiong, I. S., . . . D'Andrea, R. J. (2014). The Significance of GADD45A Promoter DNA Hypermethylation in AML: Association with IDH1/2 and TET2 Mutation. BLOOD, 124(21), 3 pages.
2014 Sadras, T., Perugini, M., Kok, C., Iarossi, D., Heatley, S., Brumatti, G., . . . D'Andrea, R. (2014). Interleukin-3-mediated regulation of β-catenin in myeloid transformation and acute myeloid leukemia. Journal of Leukocyte Biology, 96(1), 83-91.
DOI Scopus18 WoS17 Europe PMC13
2014 Pishas, K., Neuhaus, S., Clayer, M., Schreiber, A., Lawrence, D., Perugini, M., . . . Neilsen, P. (2014). Nutlin-3a efficacy in sarcoma predicted by transcriptomic and epigenetic profiling. Cancer Research, 74(3), 921-931.
DOI Scopus22 WoS22 Europe PMC22
2013 Li, S., Garrett-Bakelman, F., Akalin, A., Zumbo, P., Levine, R., To, L., . . . Mason, C. (2013). An optimized algorithm for detecting and annotating regional differential methylation. BMC Bioinformatics, 14(supp 5), 1-9.
DOI Scopus99 WoS95 Europe PMC89
2013 Diakiw, S., D'Andrea, R., & Brown, A. (2013). The double life of KLF5: Opposing roles in regulation of gene-expression, cellular function, and transformation. IUBMB Life, 65(12), 999-1011.
DOI Scopus51 WoS47 Europe PMC44
2013 Brumatti, G., Salmanidis, M., Kok, C., Bilardi, R., Sandow, J., Silke, N., . . . Ekert, P. (2013). Hoxa9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of Hoxa9-dependent leukemia. Oncotarget, 4(11), 1933-1947.
DOI Scopus46 WoS43 Europe PMC40
2013 Perugini, M., Iarossi, D., Kok, C., Cummings, N., Diakiw, S., Brown, A., . . . D'Andrea, R. (2013). GADD45A methylation predicts poor overall survival in acute myeloid leukemia and is associated with IDH1/2 and DNMT3A mutations. Leukemia, 27(7), 1588-1592.
DOI Scopus22 WoS21 Europe PMC21
2013 Kok, C., Watkins, D., Leclercq, T., D'Andrea, R., Hughes, T., & White, D. (2013). Low GFI1 expression in white blood cells of CP-CML patients at diagnosis is strongly associated with subsequent blastic transformation. Leukemia, 27(6), 1427-1430.
DOI Scopus12 WoS13 Europe PMC12
2013 Diakiw, S., Perugini, M., Kok, C., Engler, G., Cummings, N., To, L., . . . D'Andrea, R. (2013). Methylation of KLF5 contributes to reduced expression in acute myeloid leukaemia and is associated with poor overall survival. British Journal of Haematology, 161(6), 884-888.
DOI Scopus17 WoS16 Europe PMC13
2013 Watkins, D., Hughes, T., White, D., & D'Andrea, R. (2013). NPM1 mutations occur rarely or not at all in chronic myeloid leukaemia patients in chronic phase or blast crisis. Leukemia, 27(2), 489-490.
DOI Scopus11 WoS9 Europe PMC9
2013 Kok, C., Brown, A., Perugini, M., Iarossi, D., Lewis, I., & D'Andrea, R. (2013). The preferential occurrence of FLT3-TKD mutations in inv(16) AML and impact on survival outcome: A combined analysis of 1053 core-binding factor AML patients. British Journal of Haematology, 160(4), 557-559.
DOI Scopus9 WoS11 Europe PMC9
2013 Hercus, T., Dhagat, U., Kan, W., Broughton, S., Nero, T., Perugini, M., . . . Lopez, A. (2013). Signalling by the βc family of cytokines. Cytokine & Growth Factor Reviews, 24(3), 189-201.
DOI Scopus87 WoS79 Europe PMC74
2012 White, D. L., Brown, A. L., D'Andrea, R. J., & Rice, A. M. (2012). Unraveling the "known unknowns": lessons and reflections from the new directions in leukemia research 2012 conference. Cancer Research, 72(17), 4300-4303.
DOI
2012 Gagliardi, L., Ling, K., Kok, C., Carolan, J., Brautigan, P., Kenyon, R., . . . Scott, H. (2012). Genome-wide gene expression profiling identifies overlap with malignant adrenocortical tumours and novel mechanisms of inefficient steroidogenesis in familial ACTH-independent macronodular adrenal hyperplasia. Endocrine-Related Cancer, 19(3), 19-23.
DOI Scopus6 WoS6 Europe PMC5
2012 Wang, J., Hughes, T., Kok, C., Saunders, V., Frede, A., Groot Obbink, K., . . . White, D. (2012). Contrasting effects of diclofenac and ibuprofen on active imatinib uptake into leukaemic cells. British Journal of Cancer, 106(11), 1772-1778.
DOI Scopus21 WoS19 Europe PMC17
2012 Hercus, T., Broughton, S., Ekert, P., Ramshaw, H., Perugini, M., Grimbaldeston, M., . . . Lopez, A. (2012). The GM-CSF receptor family: mechanism of activation and implications for disease. Growth Factors, 30(2), 63-75.
DOI Scopus63 WoS59 Europe PMC54
2012 Jabbour, A., Gordon, L., Daunt, C., Green, B., Kok, C., D'Andrea, R., & Ekert, P. (2012). p53-dependent transcriptional responses to interleukin-3 signaling. PLoS One, 7(2), 1-11.
DOI Scopus7 WoS7 Europe PMC6
2012 Bard-Chapeau, E., Jeyakani, J., Kok, C., Muller, J., Chua, B., Gunaratne, J., . . . Copeland, N. (2012). Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors. Proceedings of the National Academy of Sciences of the United States of America, 109(6), 2168-2173.
DOI Scopus77 WoS74 Europe PMC73
2012 Rao, N., Butcher, C., Lewis, I., Ross, D., Vaz de Melo, J., Scott, H., . . . D'Andrea, R. (2012). Clonal and lineage analysis of somatic DNMT3A and JAK2 mutations in a chronic phase polycythemia vera patient. British Journal of Haematology, 156(2), 268-270.
DOI Scopus12 WoS13 Europe PMC10
2012 Diakiw, S., Kok, C., To, L., Lewis, I., Brown, A., & D'Andrea, R. (2012). The granulocyte-associated transcription factor Krüppel-like factor 5 is silenced by hypermethylation in acute myeloid leukemia. Leukemia Research, 36(1), 110-116.
DOI Scopus22 WoS21 Europe PMC21
2012 Brown, A., Salerno, D., Sadras, T., Engler, G., Kok, C., Wilkinson, C., . . . D'Andrea, R. (2012). The GM-CSF receptor utilizes β-catenin and Tcf4 to specify macrophage lineage differentiation. Differentiation, 83(1), 47-59.
DOI Scopus23 WoS21 Europe PMC20
2011 Hahn, C., Chong, C., Carmichael, C., Wilkins, E., Brautigan, P., Li, X., . . . Scott, H. (2011). Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia. Nature Genetics, 43(10), 1012-1019.
DOI Scopus543 WoS481 Europe PMC444
2011 Butcher, C., Neufing, P., Eriksson, L., Carmichael, C., Wilkins, E., Vaz de Melo, J., . . . D'Andrea, R. (2011). RUNX1 Mutations are rare in chronic phase polycythaemia vera. British Journal of Haematology, 153(5), 672-675.
DOI Scopus2 WoS2 Europe PMC2
2011 Xia, P., Wang, L., Moretti, P. A. B., Albanese, N., Chai, F., Pitson, S. M., . . . Vadas, M. A. (2011). Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-α signaling. Journal of Biological Chemistry, 286(11), 9894.
DOI
2011 Xia, P., Wang, L., Moretti, P. A. B., Albanese, N., Chai, F., Pitson, S. M., . . . Vadas, M. A. (2011). Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-α signaling (Journal of Biological Chemistry (2002) 227, (7996-8003)). Journal of Biological Chemistry, 286(49), 42785.
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2010 Rawat, V., Arseni, N., Ahmed, F., Mulaw, M., Thoenea, S., Heilmeier, B., . . . Feuring-Buskea, M. (2010). The vent-like homeobox gene VENTX promotes human myeloid differentiation and is highly expressed in acute myeloid leukemia. Proceedings of the National Academy of Sciences of the United States of America, 107(39), 16946-16951.
DOI Scopus24 WoS23 Europe PMC24
2010 Lopez, A., Hercus, T., Ekert, P., Littler, D., Guthridge, M., Thomas, D., . . . Parker, M. (2010). Molecular basis of cytokine receptor activation. IUBMB Life, 62(7), 509-518.
DOI Scopus64 WoS58 Europe PMC46
2010 Sadlon, T., Wilkinson, B., Pederson, S., Brown, C., Bresatz, S., Gargett, T., . . . Barry, S. (2010). Genome-wide identification of human FOXP3 target genes in natural regulatory T cells. Journal of Immunology, 185(2), 1071-1081.
DOI Scopus124 WoS122 Europe PMC112
2010 Hiwase, D., White, D., Powell, J., Saunders, V., Zrim, S., Frede, A., . . . Hughes, T. (2010). Blocking cytokine signaling along with intense Bcr-Abl kinase inhibition induces apoptosis in primary CML progenitors. Leukemia, 24(4), 771-778.
DOI Scopus48 WoS42 Europe PMC41
2010 Kok, C., Brown, A., Ekert, P., & D'Andrea, R. (2010). Gene expression analysis reveals HOX gene upregulation in trisomy 8 AML. Leukemia, 24(6), 1239-1243.
DOI Scopus13 WoS12 Europe PMC11
2010 Perugini, M., Brown, A., Salerno, D., Booker, G., Stojkoski, C., Hercus, T., . . . D'Andrea, R. (2010). Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common β-subunit. Blood, 115(16), 3346-3353.
DOI Scopus59 WoS52 Europe PMC45
2010 Perugini, M., Lee, H., McRae, S., & D'Andrea, R. (2010). Pharmacotherapy of chronic immune thrombocytopenic purpura (ITP) with romiplostim. Clinical Medicine Reviews in Therapeutics, 2(2), 1-7.
DOI
2009 Perugini, M., Kok, C., Brown, A., Wilkinson, C., Salerno, D., Young, S., . . . D'Andrea, R. (2009). Repression of Gadd45α by activated FLT3 and GM-CSF receptor mutants contributes to growth, survival and blocked differentiation. Leukemia, 23(4), 729-738.
DOI Scopus20 WoS19 Europe PMC21
2009 Perugini, M., Varelias, A., Sadlon, T., & D'Andrea, R. (2009). Hematopoietic growth factor mimetics: From concept to clinic. Cytokine & Growth Factor Reviews, 20(1), 87-94.
DOI Scopus25 WoS26 Europe PMC23
2009 Hutton, J., Gargett, T., Sadlon, T., Bresatz, S., Brown, C., Zola, H., . . . Barry, S. (2009). Development of CD4⁺CD25⁺FoxP3⁺ regulatory T cells from cord blood hematopoietic progenitor cells. Journal of Leukocyte Biology, 85(3), 445-451.
DOI Scopus29 WoS20 Europe PMC21
2009 Powell, J., Thomas, D., Barry, E., Kok, C., McClure, B., Tsykin, A., . . . Guthridge, M. (2009). Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML. Blood, 114(23), 4859-4870.
DOI Scopus53 WoS51 Europe PMC49
2008 Butcher, C., Hahn, U., To, L., Gecz, J., Wilkins, E., Scott, H., . . . D'Andrea, R. (2008). Two novel JAK2 exon 12 mutations in JAK2V617F-negative polycythaemia vera patients. Leukemia, 22(4), 870-873.
DOI Scopus62 WoS59 Europe PMC48
2007 Butcher, C., Hutton, J., Hahn, U., To, L., Bardy, P., Lewis, I., & D'Andrea, R. (2007). Cellular origin and lineage specificity of the JAK2(V617F) allele in polycythemia vera. Blood, 109(1), 386-387.
DOI Scopus10 WoS9 Europe PMC9
2007 Hutton, J., D'Andrea, R., & Lewis, I. (2007). Potential for clinical ex vivo expansion of cord blood haemopoietic stem cells using non-haemopoietic factor supplements. Current Stem Cell Research and Therapy, 2(3), 229-237.
DOI Scopus10 Europe PMC7
2006 Hutton, J., Rozenkov, V., Khor, F., D'Andrea, R., & Lewis, I. (2006). Bone morphogenetic protein 4 contributes to the maintenance of primitive cord blood hematopoietic progenitors in an ex vivo stroma-noncontact co-culture system. Stem Cells and Development, 15(6), 805-813.
DOI Scopus24 WoS21 Europe PMC17
2006 Brown, A., Wilkinson, C., Waterman, S., Kok, C., Salerno, D., Diakiw, S., . . . D'Andrea, R. (2006). Genetic regulators of myelopoiesis and leukemic signaling identified by gene profiling and linear modeling. Journal of Leukocyte Biology, 80(2), 433-447.
DOI Scopus39 WoS37 Europe PMC39
2004 D'Andrea, R., Sadlon, T., & Gonda, T. (2004). Overlapping motifs in the membrane-proximal region of cytokine receptor accessory and signaling subunits. Cytokine & Growth Factor Reviews, 15(2-3), 83-85.
DOI Scopus3 WoS3 Europe PMC2
2004 Sadlon, T., Lewis, I., & D'Andrea, R. (2004). BMP4: Its role in development of the hematopoietic system and potential as a hematopoietic growth factor. Stem Cells, 22(4), 457-474.
DOI Scopus79 WoS71 Europe PMC67
2004 Brown, A., Peters, M., D'Andrea, R., & Gonda, T. (2004). Constitutive mutants of the GM-CSF receptor reveal multiple pathways leading to myeloid cell survival, proliferation, and granulocyte-macrophage differentiation. Blood, 103(2), 507-516.
DOI Scopus14 WoS16 Europe PMC11
2002 Pitson, S., Moretti, P., Zebol, J., Zareie, R., Derian, C., Darrow, A., . . . Wattenberg, B. (2002). The nucleotide-binding site of human sphingosine kinase 1. Journal of Biological Chemistry, 277(51), 49545-49553.
DOI Scopus98 WoS94 Europe PMC81
2002 Xia, P., Wang, L., Moretti, P., Albanese, N., Chai, F., Pitson, S., . . . Vadas, M. (2002). Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-a signaling. Journal of Biological Chemistry, 277(10), 7996-8003.
DOI Scopus282 WoS261 Europe PMC237
2002 Blake, T., Jenkins, B., D'Andrea, R., & Gonda, T. (2002). Functional cross-talk between cytokine receptors revealed by activating mutations in the extracellular domain of the β-subunit of the GM-CSF receptor. Journal of Leukocyte Biology, 72(6), 1246-1255.
DOI Scopus37 WoS35 Europe PMC25
2001 Pitson, S., Moretti, P., Zebol, J., Vadas, M., D'Andrea, R., & Wattenberg, B. (2001). A point mutant of human sphingosine kinase 1 with increased catalytic activity. FEBS Letters, 509(2), 169-173.
DOI Scopus16 WoS16 Europe PMC15
2001 Moretti, P., Davidson, A., Baker, E., Lilley, B., Zon, L., & D'Andrea, R. (2001). Molecular cloning of a human Vent-like homeobox gene. Genomics, 76(01-Mar), 21-29.
DOI Scopus20 WoS19 Europe PMC20
2001 Jones, K., Bagley, C., Butcher, C., Barry, S., Vadas, M., & D'Andrea, R. (2001). Peptide insertions in domain 4 of hbc, the shared signalling receptor subunit for GM-CSF, IL3 and IL5, induce ligand-independent activation. Cytokine, 14(6), 303-315.
DOI Scopus2 WoS2 Europe PMC1
2001 Mc Clure, B., Woodcock, J., Harrison-Findik, D., Lopez, A., & D'Andrea, R. (2001). GM-CSF binding to its receptor induces oligomerisation of the common beta-subunit. Cytokine, 13(4), 240-243.
DOI Scopus6 WoS6 Europe PMC4
2000 Butcher, C., & D'Andrea, R. (2000). Molecular aspects of polycythemia vera (review). International Journal of Molecular Medicine, 6(3), 243-252.
DOI Scopus7 Europe PMC6
2000 D'Andrea, R., & Gonda, T. (2000). A model for assembly and activation of the GM-CSF, IL-3 and IL-5 receptors: insights from activated mutants of the common b subunit. Experimental Hematology, 28(3), 231-243.
DOI Scopus53 WoS46 Europe PMC39
2000 Xia, P., Gamble, J., Wang, L., Pitson, S., Moretti, P., Wattenberg, B., . . . Vadas, M. (2000). An oncogenic role of sphingosine kinase. Current Biology, 10(23), 1527-1530.
DOI Scopus364 WoS337 Europe PMC307
2000 Pitson, S., D'Andrea, R., Vandeleur, L., Moretti, P., Xia, P., Gamble, J., . . . Wattenberg, B. (2000). Human sphingosine kinase: purification, molecular cloning and characterization of the native and recombinant enzymes. Biochemical Journal, 350(2), 429-441.
DOI Scopus166 WoS158 Europe PMC146
2000 Pitson, S., Moretti, P., Zebol, J., Xia, P., Gamble, J., Vadas, M., . . . Wattenberg, B. (2000). Expression of a catalytically inactive sphingosine kinase mutant blocks agonist-induced sphingosine kinase activation. Journal of Biological Chemistry, 275(43), 33945-33950.
DOI Scopus173 WoS172 Europe PMC149
2000 Mulhern, T., Lopez, A., D'Andrea, R., Gaunt, C., Vandeleur, L., Vadas, M., . . . Bagley, C. (2000). The solution structure of the cytokine-binding domain of the common -chain of the receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3 and interleukin-5. Journal of Molecular Biology, 297(4), 989-1001.
DOI Scopus26 WoS26 Europe PMC21
1999 Mulhern, T., Bagley, C., Gaunt, C., Lopez, A., Vadas, M., D'Andrea, R., & Booker, G. (1999). Letter to the Editor: 1H and 15N chemical shift assignments for domain 4 of the common β-chain of the IL-3, IL-5 and GM-CSF receptors. Journal of Biomolecular NMR, 14(3), 281-282.
DOI Scopus1 WoS1 Europe PMC1
1999 Hiki, K., D'Andrea, R., Furze, J., Crawford, J., Woollatt, E., Sutherland, G., . . . Gamble, J. (1999). Cloning, characterization, and chromosomal location of a novel human K+-C1- cotransporter. Journal of Biological Chemistry, 274(15), 10661-10667.
DOI Scopus166 WoS159 Europe PMC125
1999 Sun, Q., Jones, K., McClure, B., Cambareri, B., Zacharakis, B., Iversen, P., . . . Lopez, A. (1999). Simultaneous antagonism of interleukin-5, granulocyte-macrophage colony-stimulting factor, and interleukin-3 stimulation of human eosinophils by targetting the common cytokine binding site of their receptors. Blood, 94(6), 1943-1951.
DOI Scopus61 WoS52 Europe PMC33
1998 D'Andrea, R., Harrison-Findik, D., Butcher, C., Finnie, J., Blumbergs, P., Bartley, P., . . . Vadas, M. (1998). Dysregulated hematopoiesis and a progressive neurological disorder induced by expression of an activated form of the human common β chain in transgenic mice. Journal of Clinical Investigation, 102(11), 1951-1960.
DOI Scopus29 WoS30 Europe PMC24
1997 Barry, S., Korpelainen, E., Sun, Q., Stomski, F., Moretti, P., Wakao, H., . . . Goodall, G. (1997). Roles of the N and C terminal domains of the interleukin-3 receptor alpha chain in receptor function.. Blood, 89(3), 842-852.
DOI Scopus54 WoS55 Europe PMC28
1997 Gonda, T., & D'Andrea, R. (1997). Activating mutations in cytokine receptors: implications for receptor function and role in disease.. Blood, 89(2), 355-369.
DOI Scopus45 WoS47 Europe PMC24
1996 D'Andrea, R. J., Barry, S. C., Moretti, P. A. B., Jones, K., Ellis, S., Vadas, M. A., & Goodall, G. J. (1996). Extracellular truncations of hβc, the common signaling subunit for interleukin-3 (IL-3), granulocyte-macrophage colony-stimulating factor (GM-CSF), and IL-5, lead to ligand-independent activation. Blood, 87(7), 2641-2648.
DOI Scopus25 WoS25 Europe PMC11
1995 Baird, P. N., D'andrea, R. J., & Goodall, G. J. (1995). Cytokine receptor genes: Structure, chromosomal location, and involvement in human disease. Leukemia and Lymphoma, 18(5-6), 373-383.
DOI Scopus9 WoS10 Europe PMC9
1995 Jenkins, B., D'Andrea, R., & Gonda, T. (1995). Activating point mutations in the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors suggest the involvement of beta subunit dimerization and cell type-specific molecules in signalling. EMBO Journal, 14(17), 4276-4287.
DOI Scopus76 WoS78 Europe PMC46
1994 Lonie, A., D'Andrea, R., Paro, R., & Saint, R. (1994). Molecular characterisation of the Polycomblike gene of Drosophila melanogaster, a trans-acting negative regulator of homeotic gene expression. Development, 120(9), 2629-2636.
DOI Scopus130 WoS131 Europe PMC98
1994 Yamagata, S., Isaji, M., Nakamura, K., Fujisaki, S., Doi, K., Bawden, S., & D'Andrea, R. (1994). Overexpression of the Saccharomyces cerevisiae MET17/MET25 gene in Escherichia coli and comparative characterization of the product with O-acetylserine · O-acetylhomoserine sulfhydrylase of the yeast. Applied Microbiology and Biotechnology, 42(1), 92-99.
DOI Scopus15 Europe PMC9
1994 Moretti, P., Simmons, P., Thomas, P., Haylock, D., Rathjen, P., Vadas, M., & D'Andrea, R. (1994). Identification of homeobox genes expressed in human haemopoietic progenitor cells. Gene, 144(2), 213-219.
DOI Scopus53 WoS51 Europe PMC40
1994 Barry, S. C., Bagley, C. J., Phillips, J., Dottore, M., Cambareri, B., Moretti, P., . . . Lopez, A. F. (1994). Two contiguous residues in human interleukin-3, Asp 21 and Glu 22, selectively interact with the α- and β-chains of its receptor and participate in function. Journal of Biological Chemistry, 269(11), 8488-8492.
DOI Scopus76 WoS76 Europe PMC46
1994 D'Andrea, R., Rayner, J., Moretti, P., Lopez, A., Goodall, G. J., Gonda, T. J., & Vadas, M. (1994). A mutation of the common receptor subunit for interleukin-3 (IL-3), granulocyte-macrophage colony-stimulating factor, and IL-5 that leads to ligand independence and tumorigenicity. Blood, 83(10), 2802-2808.
DOI Scopus54 WoS57 Europe PMC27
1993 Kremer, E., Baker, E., D'Andrea, R. J., Slim, R., Phillips, H., Moretti, P. A. B., . . . Goodall, G. J. (1993). A cytokine receptor gene cluster in the X-Y pseudoautosomal region?. Blood, 82(1), 22-28.
DOI Scopus44 WoS40 Europe PMC23
1993 Yamagata, S., D'Andrea, R. J., Fujisaki, S., Isaji, M., & Nakamura, K. (1993). Cloning and bacterial expression of the CYS3 gene encoding cystathionine γ-lyase of Saccharomyces cerevisiae and the physicochemical and enzymatic properties of the protein. Journal of Bacteriology, 175(15), 4800-4808.
DOI Scopus49 Europe PMC31
1993 D'Andrea, R. J., Stratmann, R., Lehner, C. F., John, U. P., & Saint, R. (1993). The three rows gene of Drosophila melanogaster encodes a novel protein that is required for chromosome disjunction during mitosis. Molecular Biology of the Cell, 4(11), 1161-1174.
DOI Scopus38 WoS38 Europe PMC30
1987 D'Andrea, R., Surdin-Kerjan, Y., Pure, G., & Cherest, H. (1987). Molecular genetics of met17 and met25 mutants of Saccharomyces cerevisiae: Intragenic complementation between mutations of a single structural gene. MGG Molecular General Genetics, 207(1), 165-170.
DOI Scopus20 Europe PMC23
1985 Wang, S. W., Robins, A. J., D'Andrea, R., & Wells, J. R. E. (1985). Inverted duplication of histone genes in chicken and disposition of regulatory sequences. Nucleic Acids Research, 13(4), 1369-1387.
DOI Scopus38 Europe PMC33
1985 D'Andrea, R. J., Coles, L. S., Lesnikowski, C., Tabe, L., & Wells, J. R. (1985). Chromosomal organization of chicken histone genes: Preferred association and inverted duplications. Molecular and Cellular Biology, 5(11), 3108-3115.
DOI Scopus51
1981 D'andrea, R., Harvey, R., & R.e. Wells, J. (1981). Vertebrate histone genes: Nucleotide sequence of a chicken H2A gene and regulatory flanking sequences. Nucleic Acids Research, 9(13), 3119-3128.
DOI Scopus24 Europe PMC28

Year Citation
2015 Voli, F., Yi, H., Martinez, B., D'Andrea, R. J., & Wang, J. Y. (2015). Gadd45a Loss Enhances MLL Leukemogenesis By Promoting Beta-Catenin Mitochondrial Translocation and Inhibiting Apoptosis. In BLOOD Vol. 126 (pp. 3 pages). Orlando, FL: AMER SOC HEMATOLOGY.
2015 Garrett-Bakelman, F. E., Li, S., Chung, S. S., Hricik, T., Franck, R., Patel, J., . . . Melnick, A. (2015). Divergent Dynamics of Epigenetic and Genetic Heterogeneity in Relapsed Acute Myeloid Leukemia. In BLOOD Vol. 126 (pp. 3 pages). Orlando, FL: AMER SOC HEMATOLOGY.
DOI WoS2
2015 Hahn, C. N., Babic, M., Schreiber, A. W., Kutyna, M. M., Wee, L. A., Brown, A. L., . . . Hiwase, D. (2015). Rare and Common Germline Variants Contribute to Occurrence of Myelodysplastic Syndrome. In BLOOD Vol. 126 (pp. 4 pages). Orlando, FL: AMER SOC HEMATOLOGY.
DOI WoS3
2014 Brown, A. L., Sadras, T., Engler, G. A., Tunningley, R., Kofler, J., Leo, P. J., . . . D'Andrea, R. J. (2014). An ENU Mutagenesis Screen of FLT3-ITD Knock-in Mice Identifies Novel Gene Mutations That Lead to an Exacerbated Myeloproliferative Neoplasm. In BLOOD Vol. 124 (pp. 3 pages). San Francisco, CA: AMER SOC HEMATOLOGY.
2011 D'Andrea, R. J., Perugini, M., Kok, C. H., Salerno, D., Danner, S., Bardy, P. G., . . . Lewis, I. D. (2011). Methylation of a Single CpG in the <i>GADD45A</i> Proximal Promoter Is Associated with Poor Survival in Acute Myeloid Leukemia. In BLOOD Vol. 118 (pp. 1511). San Diego, CA: AMER SOC HEMATOLOGY.
2011 Brown, A. L., Tunningley, R., Engler, G. A., Gilliland, D. G., Lewis, I. D., Gonda, T., & D'Andrea, R. J. (2011). An ENU Mutagenesis Screen to Identify Genes Involved in the Induction of FLT3-ITD Positive Acute Myeloid Leukemia. In BLOOD Vol. 118 (pp. 611). San Diego, CA: AMER SOC HEMATOLOGY.
2011 Rao, N., Butcher, C., Neufing, P., Bray, S., Hahn, C., Scott, H., . . . D'Andrea, R. (2011). Mechanisms of Co-operation of DNMT3A Mutations with JAK2 V617F Through Histone H4 Arginine 3 Provides New Insights in MPN Disease Pathogenesis. In 53rd ASH Annual Meeting and Exposition Vol. 118 (pp. 1). Washington DC: AMER SOC HEMATOLOGY.
WoS1
2010 Perugini, M., Brown, A. L., Diakiw, S., Kok, C., Danner, S., Lewis, I. D., & D'Andrea, R. J. (2010). REPRESSION OF GADD45A BY DNA METHYLATION IN ACUTE MYELOID LEUKEMIA (AML). In EXPERIMENTAL HEMATOLOGY Vol. 38 (pp. S54-S55). Melbourne, AUSTRALIA: ELSEVIER SCIENCE INC.
2010 Gray, J. X., Leo, P. J., Mukhopadhyay, P., Glazov, E. A., Danoy, P., Donskoi, M., . . . Gonda, T. (2010). Genome-Wide Analysis of Genetic Alterations In Acute Myeloid Leukaemia (Massively parallel, high-throughput, paired-end DNA sequencing and genotyping of an AML genome).. In BLOOD Vol. 116 (pp. 708-709). Orlando, FL: AMER SOC HEMATOLOGY.
2010 Sadras, T., Perugini, M., Ramshaw, H. S., Salerno, D. G., Lewis, I. D., Lopez, A. F., . . . D'Andrea, R. J. (2010). IL-3 MEDIATED ACTIVATION OF β-CATENIN IN ACUTE MYELOID LEUKEMIA. In EXPERIMENTAL HEMATOLOGY Vol. 38 (pp. S59). Melbourne, AUSTRALIA: ELSEVIER SCIENCE INC.
2010 Brown, A. L., Salerno, D. G., Wilkinson, C., Sadras, T., Kok, C., Perugini, M., . . . D'Andrea, R. J. (2010). THE GM-CSF RECEPTOR UTILIZES BETA-CATENIN AND TCF4 TO SPECIFY MACROPHAGE LINEAGE DIFFERENTIATION. In EXPERIMENTAL HEMATOLOGY Vol. 38 (pp. S46). Melbourne, AUSTRALIA: ELSEVIER SCIENCE INC.
2010 Powell, J. A., Thomas, D., Barry, E. F., Kok, C. H., Ma, L. Y., To, L. B., . . . Guthridge, M. A. (2010). TARGETING CELL SURVIVAL PATHWAYS IN ACUTE MYELOID LEUKEMIA. In EXPERIMENTAL HEMATOLOGY Vol. 38 (pp. S60). Melbourne, AUSTRALIA: ELSEVIER SCIENCE INC.
2007 Diakiw, S. M., Brown, A. L., Salerno, D. G., Gonda, T. J., Murphy, K., Bardy, P. G., . . . D'Andrea, R. J. (2007). Identification of oncogenes from myeloid leukemias by retroviral expression cloning. In EXPERIMENTAL HEMATOLOGY Vol. 35 (pp. 72). Hamburg, GERMANY: ELSEVIER SCIENCE INC.
2007 Perugini, M., Kok, C. H., Wilkinson, C. R., Salerno, D. G., Brown, A. L., Gonda, T. J., & D'Andrea, R. J. (2007). Down-regulation of GADD45A by FLT3 and GMCSF receptor activated mutants results in suppression of myeloid differentiation and enhanced proliferative potential. In EXPERIMENTAL HEMATOLOGY Vol. 35 (pp. 101). Hamburg, GERMANY: ELSEVIER SCIENCE INC.
2005 Brown, A. L., Wilkinson, C., Waterman, S., Salerno, D., Diakiw, S., Tsykin, A., . . . D'Andrea, R. J. (2005). Analysis of gene expression changes induced by leukaemogenic mutants of the GM-CSF receptor reveals genes important for self-renewal versus differentiation of myeloid cells. In EXPERIMENTAL HEMATOLOGY Vol. 33 (pp. 65). Univ Glasgow, Glasgow, SCOTLAND: ELSEVIER SCIENCE INC.
2005 Perugini, M., Brown, A., Gonda, T. J., & D'Andrea, R. J. (2005). Signal transduction changes induced by constitutive mutants of the granulocyte macrophage colony-stimulating factor receptor: Understanding the leukemogenic potential of mutants of the common beta subunit. In EXPERIMENTAL HEMATOLOGY Vol. 33 (pp. 87). Univ Glasgow, Glasgow, SCOTLAND: ELSEVIER SCIENCE INC.
2005 Arseni, N., Ahmed, F., Sadlon, T. J., d'Andrea, R. J., Hiddemann, W., Buske, C., & Feuring-Buske, M. (2005). The vent-like homeobox gene ventx2 is a novel candidate for a human hematopoietic regulatory protein.. In BLOOD Vol. 106 (pp. 642A). Atlanta, GA: AMER SOC HEMATOLOGY.
2004 Hutton, J. F., Khor, F., Rozenkov, V., Lewis, I. D., & D'Andrea, R. J. (2004). The role of BMP-4 in the stromal-maintenance of haematopoietic stem cells. In BLOOD Vol. 104 (pp. 475A). San Diego, CA: AMER SOC HEMATOLOGY.
DOI
2003 Butcher, C. M., Bardy, P. G., Gecz, J., Gonda, T., Cosgrove, L., & D'Andrea, R. J. (2003). The role of activating mutations in the common signalling subunit of the receptors for interieukin-3, interleukin-5 and granulocyte-macrophage colony stimulating factor in polycythemia vera.. In BLOOD Vol. 102 (pp. 341B). SAN DIEGO, CALIFORNIA: AMER SOC HEMATOLOGY.

Year Citation
2018 Inglis, D. J., Casolari, D. A., Tran, N., Beaumont, D. M., Wittwer, N. L., Ross, D., . . . Lavranos, T. C. (2018). The microtubule-disrupting drug BNC105 is a potent inducer of apoptosis in AML patient samples. Poster session presented at the meeting of Cancer research. US: American Associastion Cancer Research.
DOI
2015 Wang, J., Kok, C. H., Leclercq, T. M., Saunders, V. A., D'Andrea, R. J., Hughes, T. P., & White, D. L. (2015). High peroxisome proliferator-activated receptor-gamma (PPAR gamma le) transcriptional activity reduces active influx of imatinib and kinase inhibition in CML cells. Poster session presented at the meeting of Blood. US: American Society of Hematology.
2014 Maung, K. Z., Gray, J. X., Leo, P. J., Bassal, M., Brown, A. L., Bray, S. C., . . . Gonda, T. J. (2014). Whole Exome Sequencing of Acute Myeloid Leukaemia Patients Identifies Somatic and Germline Mutations in Fanconi Anaemia Genes. Poster session presented at the meeting of BLOOD. San Francisco, CA: AMER SOC HEMATOLOGY.
2014 Casolari, D. A., Iarossi, D. G., Butcher, C. M., Bray, S. C., Parker, W. T., Hahn, C. N., . . . D'Andrea, R. J. (2014). Aberrant activation of epidermal growth factor receptor in MPN may respond to the kinase inhibitor gefitinib. Poster session presented at the meeting of Blood. US: American Society of Hematology.
2014 Garrett-Bakelman, F., Li, S., Chung, S., Hricik, T., Rapaport, F., Mayden, C., . . . Melnick, A. (2014). DNA METHYLATION PATTERNS AT DISEASE RELAPSE IN ACUTE MYELOID LEUKEMIA TARGET CONVERGENT ELEMENTS AND PATHWAYS DESPITE INTER-PATIENT HETEROGENEITY. Poster session presented at the meeting of HAEMATOLOGICA. Milan, ITALY: FERRATA STORTI FOUNDATION.
2013 Wang, J., Kok, C. H., D'Andrea, R. J., Hughes, T. P., & White, D. L. (2013). Role Of Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) and Its Ligands In The Regulation Of Functional OCT-1 Activity In CML Cells. Poster session presented at the meeting of BLOOD. New Orleans, LA: AMER SOC HEMATOLOGY.
DOI
2012 D'Andrea, R. J., Perugini, M., Diakiw, S. M., Kok, C. H., Salerno, D., Cummings, N., . . . Lewis, I. D. (2012). Methylation of the Proximal Promoter of <i>GADD45A</i> Is Common in Acute Myeloid Leukemia and Is Associated with Poor Survival. Poster session presented at the meeting of BLOOD. Atlanta, GA: AMER SOC HEMATOLOGY.
DOI
2012 Watkins, D. B., Kok, C. H., D'Andrea, R. J., Hughes, T. P., & White, D. L. (2012). Global DNA methylation analysis identifies key pathway differences between poor (low OCT-1 activity) and standard risk CP-CML patients at diagnosis. Poster session presented at the meeting of “Abstracts of the 54th Annual Meeting and Exposition of the American Society of Hematology, as published in Blood. Atlanta, GA: America Society of Hematology.
2012 Casolari, D. A., Ishiko, J., Perugini, M., D'Andrea, R. J., & Melo, J. V. (2012). BCR-ABL-Induced Downregulation of <i>GADD45G</i> in Chronic Myeloid Leukemia. Poster session presented at the meeting of BLOOD. Atlanta, GA: AMER SOC HEMATOLOGY.
DOI
2012 Bray, S. C. E., Wee, A., Perugini, M., To, L. B., & D'Andrea, R. J. (2012). Expression of Erythroid Transcription Factors Are Decreased in a RPS19 Knockdown Cell Line Model of Diamond Blackfan Anaemia. Poster session presented at the meeting of BLOOD. Atlanta, GA: AMER SOC HEMATOLOGY.
DOI
2012 Shahrin, N. H., Brown, A. L., Diakiw, S., & D'Andrea, R. J. (2012). Investigation of KLF5 Function in Normal Hematopoiesis.. Poster session presented at the meeting of BLOOD. Atlanta, GA: AMER SOC HEMATOLOGY.
DOI
2012 Brown, A. L., Diakiw, S. M., Perugini, M., Cummings, N., Wei, A. H., To, L. B., . . . D'Andrea, R. J. (2012). A Regulatory Promoter Polymorphism and Hypermethylation of Intron 1 Are Associated with Reduced Expression of <i>KLF5</i> and Inferior Survival in AML. Poster session presented at the meeting of BLOOD. Atlanta, GA: AMER SOC HEMATOLOGY.
DOI
2011 Sadras, T., Perugini, M., Ramshaw, H. S., Salerno, D. G., Kok, C. H., Lewis, I. D., . . . D'Andrea, R. J. (2011). IL-3 REGULATES B-CATENIN IN MYELOID CELLS AND ENFORCED EXPRESSION OF B-CATENIN REDUCES THE DEPENDENCY ON IL-3 FOR SURVIVAL. Poster session presented at the meeting of EXPERIMENTAL HEMATOLOGY. ELSEVIER SCIENCE INC.

  • Exploring resistance to cord blood NK cell-based immunotherapies in acute myeloid leukaemia using ex-vivo functional models, Inner Wheel Australia Foundation Trust - Research Grant, 22/09/2025 - 31/12/2026

  • Tissue Culture Facility, Cops for Kids (via Advancement), 02/05/2024 - 30/04/2025

  • Circular RNAs: Trojan Horses of Oncogenesis, NHMRC - Project Grant, 01/01/2018 - 31/12/2021

  • FANC gene mutations in Acute Myeloid Leukaemia biology and treatment, NHMRC - Project Grant, 01/01/2018 - 31/12/2021

  • Mab immunotherapies for myeloid leukemia patients with germline or somatic RUNX1 mutations., NHMRC - Project Grant, 01/01/2018 - 31/12/2020

  • The role of the GADD45A gene in AML pathogenesis, Cancer Council SA - Beat Cancer, 01/01/2018 - 31/12/2019

  • Formation and function of circular RNAs in human cells, NHMRC - Project Grant, 01/01/2015 - 31/12/2017

  • Novel orally available small molecule kinases inhibitors, Ray and Shirl Norman Cancer Research Trust, 31/03/2014 - 31/12/2017

  • Co-operation between GATA2 mutation or expression and RAS signalling in AML, NHMRC - Project Grant, 01/01/2015 - 31/12/2017

  • The role of the GADD45A gene in AML pathogenesis and response to therapy, Cancer Council SA - Beat Cancer, 01/01/2016 - 30/06/2017

  • The role of the GADD45A gene in AML pathogenesis and response to therapy, Royal Adelaide Hospital, 01/01/2016 - 31/03/2017

Date Role Research Topic Program Degree Type Student Load Student Name
2023 Principal Supervisor Role of Inherited and Acquired Genetic Changes in the Molecular Pathogenesis of Therapy-Related Myeloid Neoplasms Doctor of Philosophy Doctorate Full Time Dr Deepak Singhal
2023 Principal Supervisor - Doctor of Philosophy Doctorate Full Time Miss Bhumika Tirthani

Date Role Research Topic Program Degree Type Student Load Student Name
2013 - 2017 Co-Supervisor Investigating Rare Pathogenic Mutations of the Extended Fanconi Anaemia DNA Repair Pathway in Acute Myeloid Leukaemia (AML) Doctor of Philosophy Doctorate Full Time Mr Kyaw Ze Ya Maung
2010 - 2015 Principal Supervisor Investigation of KLF5 function in normal haemopoiesis Doctor of Philosophy Doctorate Full Time Miss Hezrin Hezrin Shahrin
2010 - 2014 Co-Supervisor Defining CP-CML patient subsets associated with poor imatinib uptake and response Doctor of Philosophy Doctorate Full Time Mr Dale Benjamin Watkins
2009 - 2014 Principal Supervisor A Role for Histone H3, Histone H4 and Histone Associating Proteins DNMT3A and PHF6 in JAK2V617F Positive Myeloproliferative Neoplasms Doctor of Philosophy Doctorate Full Time Dr Nisha Schwarz
2009 - 2013 Principal Supervisor Investigation of the Role and Mechanism of Beta-Catenin Activation in Acute Myeloid Leukaemia Doctor of Philosophy Doctorate Full Time Dr Teresa Sadras
2008 - 2013 Co-Supervisor Investigating Drugs that Enhance Imatinib Uptake and Factors which Contribute to the Functional Activity of OCT-1 in CML Cells Doctor of Philosophy Doctorate Full Time Miss Jueqiong Wang
2006 - 2010 Principal Supervisor Identification and Functional Analysis of Gene Expression Changes in Acute Myeloid Leukaemia Doctor of Philosophy Doctorate Full Time APrf Chung Hoow Kok
2006 - 2011 Principal Supervisor Characterisation of the Role of KLF5 in Normal Haemopoiesis and Acute Myeloid Leukaemia Doctor of Philosophy Doctorate Full Time Ms Sonya Diakiw
2003 - 2007 Principal Supervisor Dissecting Signalling Contributions of the Alpha and Beta Subunits of the GM-GSF Receptor Doctor of Philosophy Doctorate Full Time Dr Michelle Perugini
2002 - 2007 Principal Supervisor The Role of BMP4 in the Ex vivo Expansion of Cord Blood Haemopoietic Stem Cells Doctor of Philosophy Doctorate Full Time Mr Jonathon Hutton
2000 - 2003 Principal Supervisor The common signalling subunit, h_c in the myeloproliferative disorder, Polycythemia Vera Master of Medical Science Master Part Time Ms Carolyn Butcher
2000 - 2007 Principal Supervisor Identification of Genes Involved in Leukaemia and Differentiation Induced by Activated Mutants of the GM-CSF Receptor ? Subunit Doctor of Philosophy Doctorate Full Time Mr Brenton Reynolds

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