Richard Le Leu
School of Psychology
Faculty of Health and Medical Sciences
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Journals
Year Citation 2024 Lunardi, L., Hill, K., Crail, S., Esterman, A., Le Leu, R., & Drummond, C. (2024). 'Supportive and Palliative Care Indicators Tool (SPICT) improves renal nurses' confidence in recognising patients approaching end of life'. BMJ Supportive and Palliative Care, 14(e1), E784-E789.
Scopus10 Europe PMC82024 Tarca, B., Jesudason, S., Wycherley, T. P., Le Leu, R., Ovenden, M., Meade, A., . . . Ferrar, K. E. (2024). Ecological Momentary Assessment to Explore Fatigue, Mood, and Physical Activity Levels in People Receiving Peritoneal Dialysis. Kidney International Reports, 9(3), 601-610.
Scopus3 WoS3 Europe PMC12024 Zhang, J., Le Leu, R. K., Xu, Q., & Bennett, P. (2024). The futility of post-haemodialysis blood glucose levels: A retrospective cohort study. Journal of Renal Care, 50(4), 323-329.
Scopus1 WoS1 Europe PMC12023 Le Leu, R., Bennett, P. N., Dansie, K., Shanahan, L., Chur-Hansen, A., Collins, K. L., . . . Jesudason, S. (2023). Changes in symptom burden in the first 6 months after dialysis commencement: a prospective longitudinal observational cohort study. Journal of Nephrology, 36(5), 1485-1488.
2023 Lunardi, L. E., Hill, K., Xu, Q., Le Leu, R., & Bennett, P. N. (2023). The effectiveness of patient activation interventions in adults with chronic kidney disease: A systematic review and meta-analysis. Worldviews on Evidence Based Nursing, 20(3), 238-258.
Scopus15 WoS12 Europe PMC82023 Welke, S., Duncanson, E., Bollen, C., Britton, A., Donnelly, F., Faull, R., . . . Jesudason, S. (2023). The impact on patients of the tertiary-primary healthcare interface in kidney failure: a qualitative study.. Journal of nephrology, 36(7), 2023-2035.
Scopus1 WoS12023 Duncanson, E. L., Chur-Hansen, A., Le Leu, R. K., Macauley, L., Burke, A. L. J., Donnelly, F. F., . . . Jesudason, S. (2023). Dialysis Needle-Related Distress: Patient Perspectives on Identification, Prevention, and Management. Kidney International Reports, 8(12), 2625-2634.
Scopus3 WoS3 Europe PMC32023 Duncanson, E., Le Leu, R. K., Chur-Hansen, A., Masotti, T., Collins, K. L., Burke, A. L. J., . . . Jesudason, S. (2023). Nephrology nurses' perspectives working with patients experiencing needle-related distress.. J Ren Care, 50(3), 241-251.
Scopus2 WoS2 Europe PMC22023 Radisic, G., Leu, R. L., Donnelly, F., Duncanson, E., Collins, K. L., Burke, A. L. J., . . . Jesudason, S. (2023). How Can Nurses Support Patients on Hemodialysis Who Experience Needle Fear? An Online Educational Intervention for Nephrology Nurses. Nephrology Nursing Journal Journal of the American Nephrology Nurses Association, 50(5), 423-428.
2022 Radisic, G., Duncanson, E., Le Leu, R., Collins, K. L., Burke, A. L. J., Turner, J. K., . . . Jesudason, S. (2022). Improving management of needle distress during the journey to dialysis through psychological education and training—the INJECT study feasibility pilot protocol. Pilot and Feasibility Studies, 8(1), 28-1-28-10.
Scopus7 WoS7 Europe PMC42021 Tarca, B., Jesudason, S., Le Leu, R., Ovenden, M., Borlace, M., Meade, A., . . . Ferrar, K. E. (2021). Ecological momentary assessment to explore fatigue, mood and physical activity levels in people receiving peritoneal dialysis: A study protocol. Peritoneal Dialysis International, 41(5), 502-508.
Scopus4 WoS4 Europe PMC32021 Meade, A., Le Leu, R., Watson, N., Jesudason, S., Clayton, P., Faull, R., . . . Trimingham, C. (2021). Gastrointestinal symptom burden and dietary intake in patients with chronic kidney disease. Journal of Renal Care, 47(4), 234-241.
Scopus3 WoS3 Europe PMC22021 Duncanson, E., Le Leu, R. K., Shanahan, L., Macauley, L., Bennett, P. N., Weichula, R., . . . Jesudason, S. (2021). The prevalence and evidence-based management of needle fear in adults with chronic disease: A scoping review. PLoS One, 16(6), e0253048-1-e0253048-16.
Scopus51 WoS44 Europe PMC352021 Hill, K., Xu, Q., Jaensch, A., Esterman, A., Le Leu, R., Childs, J., . . . Jesudason, S. (2021). “Outcomes of arteriovenous fistulae cannulation in the first 6 weeks of use: A retrospective multicenter observational study”. Journal of Vascular Access, 22(5), 726-732.
Scopus8 WoS7 Europe PMC42020 Gutman, T., Tong, A., Howell, M., Dansie, K., Hawley, C. M., Craig, J. C., . . . Better Evidence and Translation in Chronic Kidney Disease (BEAT-CKD) Workshop Investigators. (2020). Principles and strategies for involving patients in research in chronic kidney disease: report from national workshops. Nephrology Dialysis Transplantation, 35(9), 1585-1594.
Scopus20 WoS19 Europe PMC122020 Hill, K., Sharp, R., Childs, J., Esterman, A., Le Leu, R., Juneja, R., & Jesudason, S. (2020). Cannulation practices at haemodialysis initiation via an arteriovenous fistula or arteriovenous graft. Journal of Vascular Access, 21(5), 573-581.
Scopus8 WoS5 Europe PMC42019 Shanahan, L., Le Leu, R., Whittington, T., Biddle, A., McDonald, S., Bennett, P., & Jesudason, S. (2019). Needle fear: A point prevalence survey of dialysis patients. Hemodialysis International, 23(3), 285-286.
Scopus7 WoS8 Europe PMC52018 Jalleh, R., Basu, G., Le Leu, R., & Jesudason, S. (2018). Denosumab-Induced Severe Hypocalcaemia in Chronic Kidney Disease.. Case reports in nephrology, 2018, 7384763.
Europe PMC172018 Zuvela, J., Trimingham, C., Le Leu, R., Faull, R., Clayton, P., Jesudason, S., & Meade, A. (2018). Gastrointestinal symptoms in patients receiving dialysis: A systematic review. Nephrology, 23(8), 718-727.
Scopus74 WoS66 Europe PMC472018 Trimingham, C., McDonald, S., Dansie, K., Jesudason, S., Faull, R., Clayton, P., . . . Meade, A. (2018). Bowel health in chronic kidney disease: Patient perceptions differ from clinical definitions. Journal of Renal Care, 44(2), 65-72.
Scopus8 WoS6 Europe PMC42018 Nurdin, S. U., Le Leu, R. K., Aburto-Medina, A., Young, G. P., Stangoulis, J. C. R., Ball, A. S., & Abbott, C. A. (2018). Effects of dietary fibre from the traditional Indonesian food, green cincau (Premna oblongifolia merr.) on preneoplastic lesions and short chain fatty acid production in an azoxymethane rat model of colon cancer. International Journal of Molecular Sciences, 19(9), 18 pages.
Scopus10 WoS9 Europe PMC32018 Wang, K., Jin, X., Li, Q., Sawaya, A. C. H. F., Le Leu, R. K., Conlon, M. A., . . . Hu, F. (2018). Propolis from Different Geographic Origins Decreases Intestinal Inflammation and Bacteroides spp. Populations in a Model of DSS-Induced Colitis. Molecular Nutrition and Food Research, 62(17), 11 pages.
Scopus191 WoS181 Europe PMC1182018 Esmaeelian, B., Benkendorff, K., Le Leu, R. K., & Abbott, C. A. (2018). Simultaneous Assessment of the Efficacy and Toxicity of Marine Mollusc–Derived Brominated Indoles in an In Vivo Model for Early Stage Colon Cancer. Integrative Cancer Therapies, 17(2), 248-262.
Scopus8 WoS7 Europe PMC82017 Nurdin, S. U., Le Leu, R. K., Young, G. P., Stangoulis, J. C. R., Christophersen, C. T., & Abbott, C. A. (2017). Analysis of the anti-cancer effects of cincau extract (Premna oblongifolia merr) and other types of non- digestible fibre using faecal fermentation supernatants and Caco-2 cells as a model of the human colon. Nutrients, 9(4), 14 pages.
Scopus13 WoS9 Europe PMC52017 Wang, K., Jin, X., You, M., Tian, W., Leu, R. K. L., Topping, D. L., . . . Hu, F. (2017). Dietary propolis ameliorates dextran sulfate sodium-induced colitis and modulates the gut microbiota in rats fed a western diet. Nutrients, 9(8), 13 pages.
Scopus60 WoS60 Europe PMC472017 Zuvela, J., Meade, A., Trimingham, C., Jesudason, S., & Leu, R. L. (2017). GASTROINTESTINAL SYMPTOMS IN PATIENTS RECEIVING DIALYSIS: A SYSTEMATIC REVIEW. NEPHROLOGY, 22, 82. 2016 Hu, Y., Le Leu, R., Christophersen, C., Somashekar, R., Conlon, M., Meng, X., . . . Young, G. (2016). Manipulation of the gut microbiota using resistant starch is associated with protection against colitis-associated colorectal cancer in rats. Carcinogenesis, 37(4), 366-375.
Scopus151 WoS136 Europe PMC1062016 Hu, Y., McIntosh, G. H., Le Leu, R. K., Somashekar, R., Meng, X. Q., Gopalsamy, G., . . . Young, G. P. (2016). Supplementation with Brazil nuts and green tea extract regulates targeted biomarkers related to colorectal cancer risk in humans. British Journal of Nutrition, 116(11), 1901-1911.
Scopus59 WoS50 Europe PMC332016 Le Leu, R., Scherer, B., Mano, M., Winter, J., Lannagan, T., Head, R., . . . Clarke, J. (2016). Dietary butyrylated high-amylose starch reduces azoxymethane-induced colonic O⁶ -methylguanine adducts in rats as measured by immunohistochemistry and high-pressure liquid chromatography. Nutrition Research, 36(9), 982-988.
Scopus9 WoS9 Europe PMC82015 Conlon, M. A., Bird, A. R., Clarke, J. M., Le Leu, R. K., Christophersen, C. T., Lockett, T. J., & Topping, D. L. (2015). Lowering of large bowel butyrate levels in healthy populations is unlikely to be beneficial. Journal of Nutrition, 145(5), 1030-1031.
Scopus9 WoS7 Europe PMC72015 Le Leu, R., Winter, J., Christophersen, C., Young, G., Humphreys, K., Hu, Y., . . . Conlon, M. (2015). Butyrylated starch intake can prevent red meat-induced O⁶-methyl-2-deoxyguanosine adducts in human rectal tissue: a randomised clinical trial. British Journal of Nutrition, 114(2), 220-230.
Scopus128 WoS115 Europe PMC932015 Le Leu, R. K., Conlon, M. A., Bird, A. R., & Clarke, J. M. (2015). Housing experimental rats in solid-based cages with digestible bedding may confound outcomes of nutritional studies. Journal of the Science of Food and Agriculture, 95(10), 2155-2158.
Scopus10 WoS9 Europe PMC82015 Winter, J., Hu, Y., Young, G., Kohonen-Corish, M., & Le Leu, R. (2015). Role of red meat and resistant starch in promutagenic adduct formation, MGMT repair, thymic lymphoma and intestinal tumourigenesis in Msh2-deficient mice. Journal of Nutrigenetics and Nutrigenomics, 7(4-6), 299-313.
Scopus4 WoS4 Europe PMC32014 Winter, J., Young, G., Hu, Y., Gratz, S., Conlon, M., & Le Leu, R. (2014). Accumulation of promutagenic DNA adducts in the mouse distal colon after consumption of heme does not induce colonic neoplasms in the western diet model of spontaneous colorectal cancer. Molecular Nutrition and Food Research, 58(3), 550-558.
Scopus21 WoS16 Europe PMC112014 Esmaeelian, B., Abbott, C. A., Le Leu, R. K., & Benkendorff, K. (2014). 6-Bromoisatin found in muricid mollusc extracts inhibits colon cancer cell proliferation and induces apoptosis, preventing early stage tumor formation in a colorectal cancer rodent model. Marine Drugs, 12(1), 17-35.
Scopus42 WoS43 Europe PMC312014 Humphreys, K., Conlon, M., Young, G., Topping, D., Hu, Y., Winter, J., . . . Le Leu, R. (2014). Dietary manipulation of oncogenic microRNA expression in human rectal mucosa: a randomized trial. Cancer Prevention Research, 7(8), 786-795.
Scopus101 WoS85 Europe PMC682013 Martin, J., Young, G., Le Leu, R., & Hu, Y. (2013). Comparing the effects of COX and Non-COX-inhibiting NSAIDs on enhancement of apoptosis and inhibition of aberrant crypt foci formation in a rat colorectal cancer model. Anticancer Research, 33(9), 3581-3588.
Scopus6 WoS6 Europe PMC42013 Nyskohus, L., Watson, A., Margison, G., Le Leu, R., Kim, S., Lockett, T., . . . Hu, Y. (2013). Repair and removal of azoxymethane-induced O⁶-methylguanine in rat colon by O⁶-methylguanine DNA methyltransferase and apoptosis. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 758(1-2), 80-86.
Scopus21 WoS20 Europe PMC182013 Hu, Y., McIntosh, G., Le Leu, R., Nyskohus, L., Woodman, R., & Young, G. (2013). Combination of selenium and green tea improves the efficacy of chemoprevention in a rat colorectal cancer model by modulating genetic and epigenetic biomarkers. PLoS One, 8(5), e64362-1-e64362-12.
Scopus47 WoS38 Europe PMC292013 Westley, C. B., Benkendorff, K., McIver, C. M., Le Leu, R. K., & Abbott, C. A. (2013). Gastrointestinal and hepatotoxicity assessment of an anticancer extract from muricid molluscs. Evidence Based Complementary and Alternative Medicine, 2013, 12 pages.
Scopus11 WoS13 Europe PMC112013 Le Leu, R., Young, G., Hu, Y., Winter, J., & Conlon, M. (2013). Dietary red meat aggravates dextran sulfate sodium-induced colitis in mice whereas resistant starch attenuates inflammation. Digestive Diseases and Sciences, 58(12), 3475-3482.
Scopus76 WoS60 Europe PMC532013 Humphreys, K. J., Cobiac, L., Le Leu, R. K., Van der Hoek, M. B., & Michael, M. Z. (2013). Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. Molecular Carcinogenesis, 52(6), 459-474.
Scopus101 WoS89 Europe PMC722011 Hu, Y., McIntosh, G. H., Le Leu, R. K., Upton, J. M., Oodman, R. J., & Young, G. P. (2011). The influence of selenium-enriched milk proteins and selenium yeast on plasma selenium levels and rectal selenoprotein gene expression in human subjects. British Journal of Nutrition, 106(4), 572-582.
Scopus25 WoS18 Europe PMC172011 Worthley, D., Whitehall, V., Le Leu, R., Irahara, N., Buttenshaw, R., Mallitt, K., . . . Leggett, B. (2011). DNA methylation in the rectal mucosa is associated with crypt proliferation and fecal short-chain fatty acids. Digestive Diseases and Sciences, 56(2), 387-396.
Scopus23 WoS22 Europe PMC202011 Winter, J., Nyskohus, L., Young, G., Hu, Y., Conlon, M., Bird, A., . . . Le Leu, R. (2011). Inhibition by resistant starch of red meat-induced promutagenic adducts in mouse colon. Cancer Prevention Research, 4(11), 1920-1928.
Scopus66 WoS60 Europe PMC502010 Worthley, D., Whitehall, V., Buttenshaw, R., Irahara, N., Greco, S., Ramsnes, I., . . . Leggett, B. (2010). DNA methylation within the normal colorectal mucosa is associated with pathway-specific predisposition to cancer. Oncogene, 29(11), 1653-1662.
Scopus96 WoS91 Europe PMC822010 Westley, C. B., McIver, C. M., Abbott, C. A., Le Leu, R. K., & Benkendorff, K. (2010). Enhanced acute apoptotic response to azoxymethane-induced DNA damage in the rodent colonic epithelium by Tyrian purple precursors: A potential colorectal cancer chemopreventative. Cancer Biology and Therapy, 9(5), 371-379.
Scopus29 WoS28 Europe PMC242010 Hu, Y., Le Leu, R. K., Nyskohus, L. S., Winter, J., & Young, G. P. (2010). Combination of selenium and green tea improves the efficacy of chemoprevention of selenium and green tea alone in a rat colon cancer model. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 25, A73-A74. 2010 Le Leu, R. K., Winter, J., Hu, Y., Nyskohus, L., Conlon, M. A., Bird, A. R., . . . Young, G. P. (2010). High dietary protein and DNA damage in the rodent colon: regulation by resistant starch. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 25, A112-A113. 2010 Le Leu, R. K., Hu, Y., Brown, I. L., Woodman, R. J., & Young, G. P. (2010). Synbiotic intervention of Bifidobacterium lactis and resistant starch protects against colorectal cancer development in rats. Carcinogenesis, 31(2), 246-251.
Scopus174 WoS147 Europe PMC1102010 Hu, Y., McIntosh, G. H., Le Leu, R. K., & Young, G. P. (2010). Selenium-enriched milk proteins and selenium yeast affect selenoprotein activity and expression differently in mouse colon. British Journal of Nutrition, 104(1), 17-23.
Scopus31 WoS29 Europe PMC192010 Martin, J. E., Le Leu, R. K., Hu, Y., & Young, G. P. (2010). R-flurbiprofen suppresses distal nonmucin-producing colorectal tumors in azoxymethane-treated rats, without suppressing eicosanoid production. American Journal of Physiology Gastrointestinal and Liver Physiology, 298(6), G860-G864.
Scopus7 WoS7 Europe PMC42010 Leu, R. K. L., Winter, J. M., Hu, Y., Nyskohus, L. S., Conlon, M., Bird, A. R., . . . Young, G. P. (2010). M1181 Red Meat Diets Increase the Formation of O6-Methyl-2-Deoxyguanosine Adducts in the Mouse Colon: Attenuation by Resistant Starch. Gastroenterology, 138(5), S-349.
2009 Worthley, D. L., Whitehall, V. L., Buttenshaw, R., Mallitt, K. -A., Le Leu, R. K., Young, G. P., & Leggett, B. A. (2009). 199 DNA Methylation Throughout the Normal Human Colorectum: Evidence of An Epigenetic Field Effect. Gastroenterology, 136(5), A-37.
2009 Hu, Y., McIntosh, G. H., Le Leu, R. K., & Young, G. P. (2009). W1958 The Influence of Selenium-Enriched Milk Proteins On Selenium Status and Colorectal Cancer Risk in Humans. Gastroenterology, 136(5), A-761.
2009 Le Leu, R. K., Hu, Y., Brown, I. L., & Young, G. P. (2009). W1964 A Combination of Bifidobacterium Lactis and Resistant Starch Can Protect Against Colorectal Cancer Development in Rats. Gastroenterology, 136(5).
2009 Le Leu, R. K., Hu, Y., Brown, I. L., & Young, G. P. (2009). Effect of high amylose maize starches on colonic fermentation and apoptotic response to DNA-damage in the colon of rats. Nutrition and Metabolism, 6(1), 9 pages.
Scopus96 WoS83 Europe PMC602009 Worthley, D., Le Leu, R., Whitehall, V., Conlon, M., Christophersen, C., Belobrajdic, D., . . . Young, G. (2009). A human, double-blind, placebo-controlled, crossover trial of prebiotic, probiotic, and synbiotic supplementation: Effects on luminal, inflammatory, epigenetic, and epithelial biomarkers of colorectal cancer. American Journal of Clinical Nutrition, 90(3), 578-586.
Scopus132 WoS116 Europe PMC862009 Worthley, D. L., Leleu, R., Whitehall, V., Conlon, M., Christophersen, C., Belobrajdic, D., . . . Young, G. (2009). A human, double-blind, placebo-controlled, cross-over trial of prebiotic, probiotic and synbiotic supplementation: effects on luminal, inflammatory, epigenetic and epithelial biomarkers of colorectal cancer. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 24, A239. 2009 Hu, Y., Le Leu, R. K., & Young, G. P. (2009). Detection of K-ras mutations in azoxymethane-induced aberrant crypt foci in mice using LNA-mediated real-time PCR clamping and mutant-specific probes. Mutation Research Genetic Toxicology and Environmental Mutagenesis, 677(1-2), 27-32.
Scopus18 WoS19 Europe PMC112008 Worthley, D. L., Whitehall, V. L., Leleu, R., Buttenshaw, R., Young, G. P., & Leggett, B. A. (2008). DNA methylation throughout the human colorectum is associated with age, region and pathology. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 23, A206. 2008 Hu, Y., Le Leu, R. K., Belobrajdic, D., & Young, G. P. (2008). The potential of sphingomyelin as a chemopreventive agent in AOM-induced colon cancer model: Wild-type and p53+/- mice. Molecular Nutrition and Food Research, 52(5), 558-566.
Scopus13 WoS12 Europe PMC122008 Hu, Y., McIntosh, G. H., Le Leu, R. K., Woodman, R., & Young, G. P. (2008). Suppression of colorectal oncogenesis by selenium-enriched milk proteins: Apoptosis and K-ras mutations. Cancer Research, 68(12), 4936-4944.
Scopus54 WoS45 Europe PMC332008 Hu, Y., McIntosh, G. H., Le Leu, R. K., & Young, G. P. (2008). W1105 Suppression of Colon Cancer By Selenium-Enriched Milk Proteins: Enhanced Apoptotic Response to Carcinogen Is Associated with Reduction in Frequency of K-RAS Mutations. Gastroenterology, 134(4), A-634.
2007 Nutrition (2007). Journal of Gastroenterology and Hepatology, 22(s3).
2007 Hu, Y., Le Leu, R. K., & Young, G. P. (2007). Defective acute apoptotic response to genotoxic carcinogen in small intestine of APCMin/+ mice is restored by sulindac. Cancer Letters, 248(2), 234-244.
Scopus8 WoS8 Europe PMC62007 Le Leu, R. K., & Young, G. P. (2007). Fermentation of starch and protein in the colon: Implications for genomic instability. Cancer Biology and Therapy, 6(2), 259-260.
Scopus16 WoS13 Europe PMC102007 Le Leu, R. K., Brown, I. L., Hu, Y., Morita, T., Esterman, A., & Young, G. P. (2007). Effect of dietary resistant starch and protein on colonic fermentation and intestinal tumourigenesis in rats. Carcinogenesis, 28(2), 240-245.
Scopus118 WoS99 Europe PMC672007 Le Leu, R. K., Brown, I. L., Hu, Y., Esterman, A., & Young, G. P. (2007). Suppression of azoxymethane-induced colon cancer development in rats by dietary resistant starch. Cancer Biology and Therapy, 6(10), 1621-1626.
Scopus58 WoS51 Europe PMC372007 Benassi-Evans, B., Le Leu, R., Bird, A., Clifton, P., & Fenech, M. (2007). Cytokinesis-block micronucleus cytome assays for the determination of genotoxicity and cytotoxicity of cecal water in rats and fecal water in humans. Cancer Epidemiology Biomarkers & Prevention, 16(12), 2676-2680.
Scopus13 WoS10 Europe PMC62005 Young, G. P., Hu, Y., Le Leu, R. K., & Nyskohus, L. (2005). Dietary fibre and colorectal cancer: A model for environment - Gene interactions. Molecular Nutrition and Food Research, 49(6), 571-584.
Scopus137 WoS119 Europe PMC872005 Hu, Y., Le Leu, R. K., & Young, G. P. (2005). Sulindac corrects defective apoptosis and suppresses azoxymethane-induced colonic oncogenesis in p53 knockout mice. International Journal of Cancer, 116(6), 870-875.
Scopus18 WoS19 Europe PMC142005 Le Leu, R. K., Brown, I. L., Hu, Y., Bird, A. R., Jackson, M., Esterman, A., & Young, G. P. (2005). A synbiotic combination of resistant starch and Bifidobacterium lactis facilitates apoptotic deletion of carcinogen-damaged dells in rat colon. Journal of Nutrition, 135(5), 996-1001.
Scopus194 WoS157 Europe PMC832005 Hu, Y., Le Leu, R. K., & Young, G. P. (2005). Absence of acute apoptotic response to genotoxic carcinogens in p53-deficient mice is associated with increased susceptibility to azoxymethane-induced colon tumours. International Journal of Cancer, 115(4), 561-567.
Scopus32 WoS30 Europe PMC252004 Young, G. P., & Le Leu, R. K. (2004). Resistant starch and colorectal neoplasia. Journal of AOAC International, 87(3), 775-786.
Scopus39 WoS29 Europe PMC142003 Le Leu, R. K., Brown, I. L., Hu, Y., & Young, G. P. (2003). Effect of resistant starch on genotoxin-induced apoptosis, colonic epithelium, and lumenal contents in rats. Carcinogenesis, 24(8), 1347-1352.
Scopus83 WoS73 Europe PMC472002 Le Leu, R. K., Hu, Y., & Young, G. P. (2002). Effects of resistant starch and nonstarch polysaccharides on colonic luminal environment and genotoxin-induced apoptosis in the rat. Carcinogenesis, 23(5), 713-719.
Scopus64 WoS59 Europe PMC452002 Hu, Y., Martin, J., Le Leu, R., & Young, G. P. (2002). The colonic response to genotoxic carcinogens in the rat: Regulation by dietary fibre. Carcinogenesis, 23(7), 1131-1137.
Scopus47 WoS48 Europe PMC312002 Young, G. P., & Le Leu, R. K. (2002). Preventing cancer: dietary lifestyle or clinical intervention?. Asia Pacific Journal of Clinical Nutrition, 11 Suppl 3(s3), S618-S631.
Scopus23 WoS17 Europe PMC72001 McIntosh, G. H., & Le Leu, R. K. (2001). The influence of dietary proteins on colon cancer risk. Nutrition Research, 21(7), 1053-1066.
Scopus44 WoS38 Europe PMC202001 Martin, J. E., Young, G. P., James, R., Hu, Y., & Leu, R. L. (2001). Lack of interaction of sulindac and n-3 fatty acids in their effects on colo-rectal tumourigenesis. Gastroenterology, 120(5), A253.
2000 Le Leu, R. K., Young, G. P., & McIntosh, G. H. (2000). Folate deficiency reduces the development of colorectal cancer in rats. Carcinogenesis, 21(12), 2261-2265.
Scopus78 WoS71 Europe PMC512000 Le Leu, R. K., Young, G. P., & McIntosh, G. H. (2000). Folate deficiency diminishes the occurrence of aberrant crypt foci in the rat colon but does not alter global DNA methylation status. Journal of Gastroenterology and Hepatology Australia, 15(10), 1158-1164.
Scopus38 WoS34 Europe PMC241998 Le Leu, R. K., McIntosh, G. H., & Young, G. P. (1998). Ability of endogenous folate from soy protein isolate to maintain plasma homocysteine and hepatic DNA methylation during methyl group depletion in rats. Journal of Nutritional Science and Vitaminology, 44(3), 457-464.
Scopus9 WoS8 Europe PMC41996 Mcintosh, G. H., Le Leu, R. K., Royle, P. J., & Young, G. P. (1996). A comparative study of the influence of differing barley brans on DMH-induced intestinal tumours in male Sprague-Dawley rats. Journal of Gastroenterology and Hepatology Australia, 11(2), 113-119.
Scopus47 WoS38 Europe PMC261996 Noakes, M., Clifton, P. M., Nestel, P. J., Le Leu, R., & McIntosh, G. (1996). Effect of high-amylose starch and oat bran on metabolic variables and bowel function in subjects with hypertriglyceridemia. American Journal of Clinical Nutrition, 64(6), 944-951.
Scopus154 WoS139 Europe PMC911995 McIntosh, G. H., Regester, G. O., Le Leu, R. K., Royle, P. J., & Smithers, G. W. (1995). Dairy proteins protect against dimethylhydrazine-induced intestinal cancers in rats. Journal of Nutrition, 125(4), 809-816.
Scopus201 WoS175 Europe PMC881993 MCINTOSH, G. H., LELEU, R. K., KERRY, A., & GOLDRING, M. (1993). BARLEY-GRAIN FOR HUMAN FOOD USE. FOOD AUSTRALIA, 45(8), 392-394.
WoS61991 Hayball, P. J., Nation, R. L., Bochner, F., & Le Leu, R. K. (1991). Enantiospecific analysis of ketoprofen in plasma by high-performance liquid chromatography. Journal of Chromatography B Biomedical Sciences and Applications, 570(2), 446-452.
Scopus26 WoS26 Europe PMC12 -
Conference Papers
Year Citation 2012 Roediger, W., Le Leu, R., & Jones, T. (2012). DIVERSION COLITIS TREATMENT WITH RAPIDLY FERMENTABLE FIBRE-SUPPOSITORIES. In GUT Vol. 61 (pp. A93). B M J PUBLISHING GROUP.
2011 Le Leu, R., Winter, J., Hu, Y., Nyskohus, L., Conlon, M., Bird, A., . . . Young, G. (2011). Inhibition by Resistant Starch of Red Meat-Induced Promutagenic Adducts in Mouse Colon.. In ENVIRONMENTAL AND MOLECULAR MUTAGENESIS Vol. 52 (pp. S71). Montreal, CANADA: WILEY-BLACKWELL. 2011 Hu, Y., Le Leu, R. K., Nyskohus, L. S., Winter, J., & Young, G. P. (2011). Combination of Selenium and Green Tea Improves the Efficacy of Chemoprevention of Selenium and Green Tea Alone in a Rat Colon Cancer Model.. In ENVIRONMENTAL AND MOLECULAR MUTAGENESIS Vol. 52 (pp. S71). Montreal, CANADA: WILEY-BLACKWELL. 2010 Le Leu, R. K., Winter, J. M., Hu, Y., Nyskohus, L. S., Conlon, M., Bird, A. R., . . . Young, G. P. (2010). Red Meat Diets Increase the Formation of O6-Methyl-2-Deoxyguanosine Adducts in the Mouse Colon: Attenuation by Resistant Starch. In GASTROENTEROLOGY Vol. 138 (pp. S349). W B SAUNDERS CO-ELSEVIER INC. 2009 Hu, Y., McIntosh, G. H., Le Leu, R. K., & Young, G. P. (2009). The Influence of Selenium-Enriched Milk Proteins On Selenium Status and Colorectal Cancer Risk in Humans. In GASTROENTEROLOGY Vol. 136 (pp. A761). Chicago, IL: W B SAUNDERS CO-ELSEVIER INC. 2009 Le Leu, R. K., Hu, Y., Brown, I. L., & Young, G. P. (2009). A Combination of Bifidobacterium Lactis and Resistant Starch Can Protect Against Colorectal Cancer Development in Rats. In GASTROENTEROLOGY Vol. 136 (pp. A762-A763). Chicago, IL: W B SAUNDERS CO-ELSEVIER INC.
WoS12009 Worthley, D. L., Whitehall, V. L., Buttenshaw, R., Mallitt, K. -A., Le Leu, R. K., Young, G. P., & Leggett, B. A. (2009). DNA Methylation Throughout the Normal Human Colorectum: Evidence of An Epigenetic Field Effect. In GASTROENTEROLOGY Vol. 136 (pp. A37). W B SAUNDERS CO-ELSEVIER INC.
WoS12008 Le Leu, R. K., Hu, Y., Brown, I. L., & Young, G. P. (2008). Synbiotic combination of bifidobacterium lactis and resistant starch can protect against colorectal cancer development. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 23 (pp. A209). WILEY-BLACKWELL PUBLISHING, INC. 2008 Hu, Y., Mclntosh, G. H., Le Leu, R. K., & Young, G. P. (2008). Suppression of colon cancer by selenium-enriched milk proteins: Enhanced apoptotic response to carcinogen is associated with reduction in frequency of K-RAS mutations. In GASTROENTEROLOGY Vol. 134 (pp. A634). W B SAUNDERS CO-ELSEVIER INC. 2007 Hu, Y., Leleu, R., Mcintosh, G., & Young, G. (2007). Chemopreventive effect of high selenium enriched milk protein on azoxymethanc-fiaduced colonic tumorigenesis. In GASTROENTEROLOGY Vol. 132 (pp. A439). Washington, DC: W B SAUNDERS CO-ELSEVIER INC. 2006 Le Leu, R. K., Brown, I. L., Hu, Y., & Young, G. P. (2006). Effect of undigested starch and protein on intestinal tumorigenesis. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 21 (pp. A346). BLACKWELL PUBLISHING. 2006 Hu, Y., Le Leu, R. K., & Young, G. P. (2006). Detection of K-ras mutation in AOM-induced colonic tumorigenesis by locked nucleic acid (LNA)-mediated PCR clamping and melting curve analysis. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 21 (pp. A268). BLACKWELL PUBLISHING. 2004 Hu, Y., Le Leu, R. K., & Young, G. P. (2004). Effect of sulindac on acute apoptotic response to carcinogen in p53 knockout mice. In GASTROENTEROLOGY Vol. 126 (pp. A303). New Orleans, LA: W B SAUNDERS CO. 2003 Martin, J., Leu, L., Hu, Y., & Young, G. (2003). Prevention of colorectal carcinoma in azoxymethane treated rats by non-steroidal anti-inflammatory drugs (NSAIDs) is dependent on histologic type. In GASTROENTEROLOGY Vol. 124 (pp. A604). ORLANDO, FLORIDA: W B SAUNDERS CO.
2002 Hu, Y., Le Leu, R. K., Martin, J. E., & Young, G. (2002). The acute apoptotic response in the colon to DNA damage by carcinogen is dependent on p53 but not APC. In GASTROENTEROLOGY Vol. 122 (pp. A684). W B SAUNDERS CO. 2001 Martin, J. E., Young, G. P., James, R., Hu, Y., & Le Leu, R. (2001). Lack of interaction of sulindac and n-3 fatty acids in their effects on colo-rectal tumourigenesis. In GASTROENTEROLOGY Vol. 120 (pp. A253). W B SAUNDERS CO.
2001 Le Leu, R. K., Hu, Y., & Young, G. P. (2001). Effects of resistant starch and nonstarch polysaccharides on luminal environment and AOM-induced apoptosis. In GASTROENTEROLOGY Vol. 120 (pp. A667). W B SAUNDERS CO.
1999 Le Leu, R. K., McIntosh, G. H., & Young, G. P. (1999). Effect of folate deficiency on formation of azoxy-methane-induced aberrant crypt foci in the rat colon. In GASTROENTEROLOGY Vol. 116 (pp. A449). W B SAUNDERS CO-ELSEVIER INC.
WoS11998 McIntosh, G. H., Royle, P. J., Le Leu, R. K., Regester, G. O., Johnson, M. A., Grinsted, R. L., . . . Smithers, G. W. (1998). Whey proteins as functional food ingredients?. In International Dairy Journal Vol. 8 (pp. 425-434). IRELAND, CORK: ELSEVIER SCI LTD.
Scopus154 WoS132 Europe PMC421996 Noakes, M., Clifton, P. M., Nestel, P. J., LeLeu, R., & McIntosh, G. (1996). Effect of high amylose starch and oat bran on metabolic variables and bowel function in subjects with hypertriglyceridemia. In J. C. B. Miller (Ed.), PROCEEDINGS OF THE NUTRITION SOCIETY OF AUSTRALIA, VOL 20 Vol. 20 (pp. 192). SYDNEY, AUSTRALIA: NUTRITION SOC AUSTRALIA. -
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