Dr Maleesa Pathirana
Study Coordinator
Adelaide Medical School
Faculty of Health and Medical Sciences
Dr Maleesa Pathirana is an adjunct associate lecturer and early career postdoctoral fellow at The University of Adelaide and Robinson Research Institute. She is a research member of the Northern Cardiology Research Group led under A/Prof Margaret Arstall.
Maleesa completed her PhD in 2022. She works as a clinical researcher under the Department of Cardiology at the Lyell McEwin Hospital, and with the Robinson Research Institute and Adelaide Medical School
Her research interests include:
-Coordination and management of clinical trials and observational clinical studies.
-Cardiovascular risk and prevention of early onset heart disease in women
-The effect of lactation on improving metabolic syndrome risk after a major pregnancy complication
-The effect of major pregnancy complications on maternal and child cardio-metabolic health
-Metabolic health in the first 1000 days.
-Preventative health in vulnerable people and individuals from low socioeconomic backgrounds
- My Research
- Career
- Publications
- Grants and Funding
- Teaching
- Supervision
- Professional Activities
- Contact
Northern Cardiovascular Research Group (Lyell McEwin Hospital)
Our research group aims to improve outcomes for people with cardiovascular disease in northern Adelaide. Our main research themes include management of coronary heart disease, heart disorders during pregnancy, and heart disease in women. We are a passionate team of clinicians and scientists who have a strong focus on collaborative clinical research in a hospital setting. The diversity of our research strengths and methods means that there are many opportunities for students to explore and develop their own research interests.
My research interests: I am interested in the effect of pregnancy complications on cardiometabolic heath in women and young children, and understanding what risk factors are prevalent in is cohort to allow for early treatment and intervention for early onset metabolic syndrome and heart disease later in life.
Research Project 1 - Pregnancy and heart disease
Project description: This project seeks to explore the influence of pregnancy complications on future health of women who present to the Lyell McEwin Hospital with heart disease. Traditional risk factors for heart disease include hypertension, diabetes, smoking and obesity. There is clear evidence indicating that pregnancy complications should be counted as equally important risk factors, but they are not routinely considered by clinicians in risk assessments. This clinical project will recruit inpatients and administering pregnancy history questionnaires.
Projects available for: Honours / HDR / Masters
Location: LMH
Research project start: Semester 1 and 2
Special requirements: Police clearance and vaccinations
Research Project 2 - Cardiovascular assessment after obstetric complications: follow-up for education and evaluation (COFFEE)
Project description: This study encompasses clinical, lab-based, and qualitative projects with a strong emphasis on translatable research. Women who experience complications of pregnancy have an increased risk of developing future cardiovascular disease. The COFFEE program is the first Australian research-informed, clinical-based postpartum initiative for women who have had a pregnancy complication. We have a range of social, clinical and lab-based research projects that can be tailored to student interests.
Projects available for: Third Year / Honours / HDR / Masters
Location: LMH
Research project start: Semester 1 and 2
Special requirements: Police clearance and vaccinations
Research Project 3 – The effect of pregnancy complications and lifestyle on the health of mother and child
Project description: This clinical project focuses on following up women and children to measure cardiovascular and other risk factors. A range of sub-projects may be developed to focus on clinical and social influences of maternal and child health.
Projects available for: Honours / HDR / Masters
Location: LMH
Research project start: Semester 1 and 2
Special requirements: Police clearance and vaccinations
Research Project 4 – The effect of breastfeeding on reducing cardiovascular disease risk in young women
Project description: This study focuses on how breastfeeding intensity and duration can mitigate cardiovascular risk factors in young women who have experienced pregnancy complications. A range of sub-projects may be developed to focus on clinical and social influences of breastfeeding on maternal metabolic health.
Projects available for: Honours / HDR / Masters
Location: LMH
Research project start: Semester 1 and 2
Special requirements: Police clearance and vaccinations
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Appointments
Date Position Institution name 2022 - ongoing Adjunct Associate Lecturer The University of Adelaide 2022 - ongoing Study Coordinator Lyell McEwin Hospital 2021 - ongoing Study Coordinator The University of Adelaide 2020 - 2022 Research Officer - CADOSA The University of Adelaide 2019 - 2019 Research Assistant The University of Adelaide 2019 - 2022 HDR Representative RRI Early Mid Career Research Council -
Language Competencies
Language Competency English Can peer review -
Education
Date Institution name Country Title 2018 - 2022 The University of Adelaide Australia Doctor of Philosophy 2017 - 2017 The University of Adelaide Australia Bachelor of Health and Medical Sciences (Honours in Obstetrics and Gynaecology) 2014 - 2016 Flinders University Australia Bachelor of Medical Science -
Certifications
Date Title Institution name Country — ICH GCP Certification Praxis Australia - — Venepuncture Training Lyell McEwin Hospital Australia -
Research Interests
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Journals
Year Citation 2024 Khoja, A., Andraweera, P. H., Lassi, Z. S., Padhani, Z. A., Ali, A., Zheng, M., . . . Arstall, M. A. (2024). Modifiable and Non-Modifiable Risk Factors for Premature Coronary Heart Disease (PCHD): Systematic Review and Meta-Analysis. Heart Lung and Circulation, 33(3), 265-280.
Scopus1 Europe PMC12024 Namkoong, J., Andraweera, P. H., Pathirana, M., Munawar, D., Downie, M., Edwards, S., . . . Arstall, M. A. (2024). A systematic review and meta-analysis of the diagnosis and surgical management of carcinoid heart disease. Frontiers in Cardiovascular Medicine, 11, 13 pages.
Scopus1 Europe PMC22024 Takele, W. W., Vesco, K. K., Josefson, J., Redman, L. M., Hannah, W., Bonham, M. P., . . . Lim, S. (2024). Effective interventions in preventing gestational diabetes mellitus: A systematic review and meta-analysis. Communications Medicine, 4(1), 75-1-75-15.
Scopus42023 Andraweera, P. H., Plummer, M. D., Garrett, A., Leemaqz, S., Wittwer, M. R., Aldridge, E., . . . Arstall, M. A. (2023). Early pregnancy cardio metabolic risk factors and the prevalence of metabolic syndrome 10 years after the first pregnancy. PLOS ONE, 18(1), 1-11.
Scopus3 Europe PMC12023 Khoja, A., Andraweera, P. H., Lassi, Z. S., Ali, A., Zheng, M., Pathirana, M. M., . . . Arstall, M. A. (2023). Risk Factors for Premature Coronary Heart Disease in Women Compared to Men: Systematic Review and Meta-Analysis. Journal of Women's Health, 32(9), 908-920.
Scopus4 WoS32023 Jones, M. N., Palmer, K. R., Pathirana, M. M., Cecatti, J. G., Filho, O. B. M., Marions, L., . . . Li, W. (2023). Balloon Catheters Versus Vaginal Prostaglandins for Labour Induction (CPI Collaborative): An Individual Participant Data Meta-analysis of Randomised Controlled Trials. Obstetrical and Gynecological Survey, 78(5), 255-257.
2023 Pathirana, M. M., Andraweera, P. H., Aldridge, E., Harrison, M., Harrison, J., Leemaqz, S., . . . Roberts, C. T. (2023). The association of breast feeding for at least six months with hemodynamic and metabolic health of women and their children aged three years: an observational cohort study.. Int Breastfeed J, 18(1), 1-12.
Scopus3 Europe PMC12023 Lim, S., Takele, W. W., Vesco, K. K., Redman, L., & Josefson, J. (2023). A systematic review and meta-analysis of participant characteristics in the prevention of gestational diabetes: a summary of evidence for precision medicine.
2023 Khoja, A., Andraweera, P. H., Lassi, Z. S., Ali, A., Zheng, M., Pathirana, M. M., . . . Arstall, M. A. (2023). Risk Factors for Early-Onset Versus Late-Onset Coronary Heart Disease (CHD): Systematic Review and Meta-Analysis. Heart Lung and Circulation, 32(11), 1277-1311.
Scopus5 Europe PMC22023 Lim, S., Takele, W. W., Vesco, K. K., Redman, L. M., Hannah, W., Bonham, M. P., . . . Støy, J. (2023). Participant characteristics in the prevention of gestational diabetes as evidence for precision medicine: a systematic review and meta-analysis. Communications Medicine, 3(1), 137.
Scopus9 Europe PMC72023 Tobias, D. K., Merino, J., Ahmad, A., Aiken, C., Benham, J. L., Bodhini, D., . . . Franks, P. W. (2023). Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine.. Nature medicine, 29(10), 2438-2457.
Scopus68 WoS7 Europe PMC522023 Pathirana, M. M., Andraweera, P. H., Leemaqz, S., Aldridge, E., Arstall, M. A., Dekker, G. A., & Roberts, C. T. (2023). Anxiety and Depression in Early Gestation and the Association with Subsequent Gestational Diabetes Mellitus in a Disadvantaged Population. Maternal and Child Health Journal, 27(12), 2185-2193.
Scopus2 Europe PMC12023 Aldridge, E., Pathirana, M., Wittwer, M., Sierp, S., Roberts, C. T., Dekker, G. A., & Arstall, M. (2023). Women's awareness of cardiovascular disease risk after complications of pregnancy. Women and Birth, 36(3), e335-e340.
Scopus2 Europe PMC12022 Jones, M. N., Palmer, K. R., Pathirana, M. M., Cecatti, J. G., Filho, O. B. M., Marions, L., . . . Li, W. (2022). Balloon catheters versus vaginal prostaglandins for labour induction (CPI Collaborative): an individual participant data meta-analysis of randomised controlled trials. Lancet, 400(10364), 1681-1692.
Scopus19 WoS6 Europe PMC82022 Aldridge, E., Schubert, K. O., Pathirana, M., Sierp, S., Leemaqz, S. Y., Roberts, C. T., . . . Arstall, M. A. (2022). A prospective registry analysis of psychosocial and metabolic health between women with and without metabolic syndrome after a complicated pregnancy. BMC Women's Health, 22(1), 1-9.
Scopus1 Europe PMC12022 Aldridge, E., Pathirana, M., Wittwer, M., Sierp, S., Leemaqz, S. Y., Roberts, C. T., . . . Arstall, M. A. (2022). Prevalence of Metabolic Syndrome in Women After Maternal Complications of Pregnancy: An Observational Cohort Analysis. Frontiers in Cardiovascular Medicine, 9, 1-9.
Scopus4 WoS3 Europe PMC22022 Pathirana, M. M., Lassi, Z. S., Roberts, C. T., & Andraweera, P. H. (2022). Author response to: Cardiovascular risk factors in offspring exposed to gestational diabetes mellitus in utero: systematic review and meta-analysis. Journal of Developmental Origins of Health and Disease, 13(6), 813-814.
WoS22022 Pathirana, M. M., Lassi, Z. S., Roberts, C. T., & Andraweera, P. H. (2022). Erratum: Author response to: Cardiovascular risk factors in offspring exposed to gestational diabetes mellitus in utero: systematic review and meta-analysis (Journal of Developmental Origins of Health and Disease (2022) (1–2) DOI: 10.1017/S2040174422000174). Journal of Developmental Origins of Health and Disease, 13(6), 815.
2022 Pathirana, M. M., Andraweera, P. H., Aldridge, E., Leemaqz, S. Y., Harrison, M., Harrison, J., . . . Roberts, C. T. (2022). Gestational diabetes mellitus and cardio-metabolic risk factors in women and children at 3 years postpartum. Acta Diabetologica, 59(9), 1237-1246.
Scopus5 WoS4 Europe PMC62022 Andraweera, P. H., Lassi, Z. S., Pathirana, M. M., Plummer, M. D., Dekker, G. A., Roberts, C. T., & Arstall, M. A. (2022). Pregnancy complications and cardiovascular disease risk perception: A qualitative study. PloS one, 17(7), 1-9.
Scopus8 WoS1 Europe PMC32022 Aldridge, E., Pathirana, M., Wittwer, M., Sierp, S., Leemaqz, S. Y., Roberts, C. T., . . . Arstall, M. A. (2022). Effectiveness of a nurse practitioner-led cardiovascular prevention clinic at reduction of metabolic syndrome following maternal complications of pregnancy: a preliminary analysis. Diabetology and Metabolic Syndrome, 14(1), 144.
Scopus3 Europe PMC12021 Pathirana, M. M., Lassi, Z. S., Bachlani, A. A., Arstall, M. A., Roberts, C. T., & Andraweera, P. H. (2021). Association between metabolic syndrome and gestational diabetes mellitus in women and their children: a systematic review and meta-analysis. Endocrine, 71(2), 310-320.
Scopus34 WoS20 Europe PMC212021 Pathirana, M. M., Lassi, Z., Ali, A., Arstall, M., Roberts, C. T., & Andraweera, P. H. (2021). Cardiovascular risk factors in women with previous gestational diabetes mellitus: a systematic review and meta-analysis. Reviews in Endocrine and Metabolic Disorders, 22(4), 729-761.
Scopus35 WoS23 Europe PMC262021 Pathirana, M. M., Bachlani, A. A., Lassi, Z. S., Arstall, M. A., Roberts, C. T., & Andraweera, P. H. (2021). Protective Influence of Breastfeeding on Cardiovascular Risk Factors in Women With Previous Gestational Diabetes Mellitus and Their Children: A Systematic Review and Meta-Analysis. Journal of Human Lactation, 18(3), 089033442110347.
Scopus13 WoS7 Europe PMC112021 Khoja, A., Andraweera, P. H., Lassi, Z. S., Zheng, M., Pathirana, M. M., Ali, A., . . . Arstall, M. A. (2021). Risk factors for premature coronary artery disease (PCAD) in adults: a systematic review protocol. F1000Research, 10, 1228.
Scopus11 Europe PMC62020 Pathirana, M. M., Lassi, Z. S., Roberts, C. T., & Andraweera, P. H. (2020). Cardiovascular risk factors in offspring exposed to gestational diabetes mellitus in utero: systematic review and meta-analysis. Journal of Developmental Origins of Health and Disease, 11(6), 599-616.
Scopus60 WoS37 Europe PMC352020 Pathirana, M. M., Lassi, Z. S., Roberts, C. T., & Andraweera, P. H. (2020). Author response: cardiovascular risk factors in offspring exposed to gestational diabetes mellitus in utero: systematic review and meta-analysis.. Journal of developmental origins of health and disease, 11(3), 1-2.
Scopus1 WoS6 Europe PMC1 -
Conference Items
Year Citation 2023 Schubert, K. O., Pathirana, M., FUGARO, P., Onf, H., Fenech, D., GUIDOLIN, M., . . . Wright, S. (2023). EXTERNAL AND SERVICE FACTORS INFLUENCING OUTCOMES IN A MODEL OF STRATIFIED MENTAL HEALTH SERVICES FOR YOUNG PEOPLE. Poster session presented at the meeting of International Conference on Early Intervention 14. Luscerne, Switzerland. 2022 Jones, M., Palmer, K., Pathirana, M. M., Cecatti, J. G., Filho, O. B. M., Marions, L., . . . Li, W. (2022). A comparison of balloon catheters and vaginal prostaglandins for cervical ripening prior to labour induction. Poster session presented at the meeting of AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. MOSBY-ELSEVIER.
WoS1
2024 - Lloyd Cox Research Fellowship
2024 - Northern Adelaide Local Health Network Divisional Directorate Grant (PI)
2024 - RRI Step Up Grant (CI)
2023/24 - Womens Health Research Translation Network EMCR Award
2023 - Robinson Research Institute Travel Grant
2023 - Faculty of Health and Medical Sciences Building Research Leaders Grant (PI)
2022 - RRI Engaging Opportunities Grant (co-investigator)
2022 - Robinson Research Institute Travel Grant
2022 - E O Meyers Trust Heart Foundation Travel Grant
2019 - Hospital Research Foundation Travel Grant
2022 - Robinson Research Institute Travel Grant
2018 - 2021 - Faculty of Health and Medical Sciences Divisional Scholarship - PhD
Current teaching roles:
BHMS Year 3 Research Placement Course
Research and Critical Appraisal, MBBS year 3 (Med Stud 3014A and B)
Bachelor of Health Sciences Honours Research (AMS)
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Other Supervision Activities
Date Role Research Topic Location Program Supervision Type Student Load Student Name 2024 - ongoing Principal Supervisor Microvascular health in postpartum women with previous hypertensive disorders of pregnancy University of Adelaide - Honours Full Time Dena Herrmann 2024 - ongoing Principal Supervisor Differences in psycho social factors between those who attend and do not attend a postpartum cardiovascular preventative clinic University of Adelaide - Other Part Time Katrina Maguera, Han Lynn Zaw, Rachel Unkwiye, Georgia Wyatt-Read 2023 - ongoing Principal Supervisor Cardiovascular risk factors in women and children exposed to hypertensive disorders of pregnancy at 3 years post pregnancy The University of Adelaide - Other Full Time Jack Sargent, Stanley Lii, Thomas Nguyen, Dena Hermann 2023 - ongoing Principal Supervisor Microvascular function in women with a previous pregnancy complication at 6 months postpartum The University of Adelaide - Honours Full Time Stevie Young 2022 - 2022 Principal Supervisor Investigating the socioeconomic factors that influence attendance to a postpartum cardiovascular disease prevention clinic for women with a history of pregnancy complications The University of Adelaide - Honours Full Time Lauran Hinter 2021 - ongoing Principal Supervisor Insulin resistance in offspring exposed to gestational diabetes mellitus Robinson Research Institute, The University of Adelaide 4th Year Medicine Research Project Other Full Time Cicilia Gomes 2021 - ongoing Principal Supervisor Insulin resistance in offspring exposed to gestational diabetes mellitus The University of Adelaide 4th Year Medicine Research Project Other Full Time Nipun Herath 2021 - ongoing Principal Supervisor Insulin resistance in offspring exposed to gestational diabetes mellitus The University of Adelaide 4th Year Medicine Research Project Other Full Time Elise Toyer 2021 - ongoing Principal Supervisor Insulin resistance in offspring exposed to gestational diabetes mellitus The University of Adelaide 4th Year Medicine Research Project Other Full Time Kayla Koh 2020 - 2021 Co-Supervisor Inter-pregnancy Interval and Risk of Cardiovascular Disease The University of Adelaide Third Year Health and Medical Science Placement Other Full Time Lorraine Cometa 2020 - ongoing Co-Supervisor Gestational Hypertension and risk of cardiovascular disease The University of Adelaide - Other - Ayani Gamage
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Committee Memberships
Date Role Committee Institution Country 2024 - ongoing Member South Australian Cardiovascular Research Network Rising Stars Sub-Committee SA CVRN Australia 2023 - ongoing Member Womens Health Translational Network SA Executive Committee WHRTN SA Australia 2023 - ongoing Representative HiPPP-EMR C CRE-HiPPP Australia -
Memberships
Date Role Membership Country 2022 - ongoing Member Health in Preconception, Pregnancy and Postpartum EMR-C Collective Australia 2019 - ongoing Member Australian Society of Medical Research Australia 2018 - ongoing Member DOHaD ANZ Australia 2018 - ongoing Member Healthy Development Adelaide Australia
Connect With Me
External Profiles