Research Interests
Allergy Applied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies) Immunology Infectious Diseases Transplantation Immunology Vaccinology Immunology and Infection Innovative Therapeutics Surgical and Health Systems Innovation Translational Health OutcomesMr Griffith Perkins
School of Medicine
College of Health
Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.
I am an early career researcher with the Centre for Clinical and Experimental Transplantation. I trained in immunology under Professor Toby Coates and Drs Plinio Hurtado and Chris Hope at the University of Adelaide. I currently hold the Mary Overton Early Career Fellowship from the Royal Adelaide Hospital, and appointments with the Adelaide Medical School, SA Pathology, and the International Society of Nephrology. Under the mentorship of Professor Coates, I lead a team of clinicians and scientists undertaking bench-to-bedside translational research to understand and improve protective vaccine responses in immunocompromised populations. Over the last few years, pursuing this goal has taken us from in-depth clinical and molecular immunology to two interventional clinical trials, and has led to excellent collaborations with interstate and international colleagues and people affected by a range of immune-compromising conditions.
My research area is clinical and translational immunology, with a strong grounding in laboratory sciences. Since starting out in 2019, I have presented my research at 10 domestic and 8 international conferences, and have co-authored 40 publications in peer-reviewed journals, including Kidney International, the Journal of Allergy and Clinical Immunology, Blood Cancer Journal, Gut, and Nature Immunology.
Immunosuppression & Vaccine Response
Transplant recipients receive immunosuppressive drugs to prevent their immune system from attacking the 'non-self' transplant. During my PhD I described the severe impact that these drugs have on the antibody and T cell responses to SARS-CoV-2 vaccination in kidney transplant recipients (KTRs), many of whom remain highly vulnerable to COVID-19 and other vaccine-preventable infections (VPIs). In my current fellowship, I am working with a team of five HDR candidates, and local and interstate clinicians, immunologists and virologists, to develop and test strategies to improve long-lived and cross-protective immunity of KTRs against key VPIs - COVID-19, Influenza, Shingles. This work has uncovered two promising targets for intervention to restore patients' T cell and antibody responses: the mechanistic target of rapamycin complex 1 (mTORC1) in T cells, and immunomodulatory microbial species within the gut. We recently completed two multi-centre, randomised controlled trials exploiting these targets in KTRs to improve their response to SARS-CoV-2 booster vaccination.
We are also investigating vaccine responses in people with multiple sclerosis (pwMS), end-stage kidney disease (ESKD), myelofibrosis (MF), and haematopoietic stem cell transplant (HSCT) recipients.
Vaccine Allergy & Tolerance
A small percentage of people experience hypersensitivity reactions to the novel mRNA nanoparticle vaccines against COVID-19. During the pandemic I worked with the Royal Adelaide Hospital Immunology Department and SA Pathology to develop a diagnostic test to stratify individuals at-risk of adverse reaction. We found that the sensitivity of people with allergy to the mRNA vaccines is dependent on the arrangement of polyethylene glycol (PEG) molecules on the surface of the lipid nanoparticle. This property enabled us to massively improve diagnostic sensitivity and reliably diagnose PEG allergy from a blood test.
This collaboration has led to ongoing trials investigating mechanisms and biomarkers of allergic desensitisation in people undergoing venom immunotherapy, and of Bruton's tyrosine kinase inhibitors for the prevention of exercise-induced anaphylaxis.
Centre for Clinical & Experimental Transplantation
The lab under Prof Coates runs a number of other translational research streams that are also available as projects for Honours, M.Phil and PhD students, including:
- Engineered Chimeric Antigen Receptor T regulatory cells (CAR Tregs) as an immunotherapy for type 1 diabetes
- 3-dimensional bioprinting of pancreatic islets and supporting cell types for type 1 diabetes
- Subcutaneous transplantation of pancreatic islets in large animal models and first-in-human trial
- Establishing total pancreatectomy with islet auto-transplantation (TPIAT) as a newly available, reimbursed cure for pancreatitis in Australia
- Patient-derived organoids to model hereditary pancreatitis
- Genetic epidemiology of hereditary pancreatitis in Australia
| Date | Position | Institution name |
|---|---|---|
| 2023 - ongoing | Kidney International Editorial Fellow | International Society of Nephrology |
| 2023 - ongoing | Mary Overton Early Career Research Fellow | Royal Adelaide Hospital |
| 2023 - ongoing | Adjunct Senior Lecturer | University of Adelaide |
| 2023 - 2024 | Affiliate Researcher in Immunology | SA Pathology |
| Date | Type | Title | Institution Name | Country | Amount |
|---|---|---|---|---|---|
| 2026 | Award | Travel Grant to attend the World Congress of Nephrology | International Society of Nephrology | Japan | - |
| 2025 | Award | Travel Award to attend the 53rd Annual Scientific Meeting | Australian & New Zealand Society for Immunology | Australia | - |
| 2025 | Award | Travel Grant to attend the Annual Scientific Meeting of the Transplantation Society of Australia and New Zealand | Kidney, Transplant & Diabetes Australia | Australia | - |
| 2025 | Research Award | Early Career Researcher Award | Transplantation Society of Australia and New Zealand | Australia | - |
| 2024 | Award | Travel Award - ASI Clinical Translational School | Australia & New Zealand Society for Immunology | Australia | - |
| 2024 | Award | Finalist, Premier's Excellence Award - Emerging Young Talent | Government of South Australia | Australia | - |
| 2023 | Fellowship | Kidney International Editorial Fellowship | International Society of Nephrology | United States | - |
| 2023 | Fellowship | Mary Overton Early Career Fellowship | Royal Adelaide Hospital | Australia | $312,000 |
| 2023 | Award | Advanced Immunology School Award for Outstanding Contribution | Australian and New Zealand Society for Immunology | Australia | $250 |
| 2022 | Research Award | Early Career Researcher Award | Transplantation Society of Australia and New Zealand | Australia | Flights & Registration |
| 2022 | Research Award | Dean’s Commendation for Doctoral Thesis Excellence | University of Adelaide | Australia | - |
| 2022 | Research Award | President's Prize | Transplantation Society of Australia and New Zealand | Australia | $3,000 |
| 2022 | Research Award | People's Choice Award | Transplantation Society of Australia and New Zealand | Australia | $500 |
| 2022 | Award | Travel grant to attend the 29th International Congress of The Transplantation Society | The Transplantation Society | Canada | $3,500 |
| 2022 | Award | Travel grant to attend the 13th American Transplant Congress | Transplantation Society of Australia and New Zealand | Australia | $2,500 |
| 2021 | Award | Kidney International Reviewer of the Year | International Society of Nephrology | United States | - |
| 2021 | Research Award | Early Career Researcher Award | Transplantation Society of Australia and New Zealand | Australia | Flights & Registration |
| 2019 | Research Award | Young Investigator Award | Transplantation Society of Australia and New Zealand | Australia | Flights & Registration |
| 2019 | Research Award | Mentee-Mentor Award | American Society of Transplantation | United States | $2,500 |
| 2019 | Award | Travel grant to attend the 17th World Congress of the International Pancreas and Islet Transplantation Association | Transplantation Society of Australia and New Zealand | Australia | $2,500 |
| 2018 | Scholarship | Master of Philosophy (No Honours) Scholarship | University of Adelaide | Australia | $94,616 |
| 2018 | Award | Travel grant to attend the Transplantation Science Symposium Asian Regional Meeting | Transplantation Society of Taiwan | Taiwan, Province of China | $750 |
| Date | Institution name | Country | Title |
|---|---|---|---|
| 2022 - 2022 | University of Adelaide | Australia | PhD |
| 2017 - 2017 | University of Adelaide | Australia | BSc(Adv) |
| 2017 - 2017 | University of Adelaide | Australia | DipLang |
| Year | Citation |
|---|---|
| 2025 | Zhang, Z. J., Casiraghi, F., Perkins, G. B., Baldwin, W. M., & Fairchild, R. L. (2025). Can mouse kidney transplant models inform mechanisms of injury and acceptance in clinical kidney transplantation?. American Journal of Transplantation, 25(7), 1391-1398. Scopus1 WoS1 Europe PMC1 |
| 2025 | Perkins, G. B., Tunbridge, M. J., Chai, C. S., Hope, C. M., Lip Yeow, A. E., Salehi, T., . . . Coates, P. T. (2025). mTOR Inhibitors and Vaccine Response in Kidney Transplant Recipients.. J Am Soc Nephrol, 36(11), 2213-2227. Scopus1 WoS1 Europe PMC1 |
| 2025 | Perkins, G. B., Lim, A. H., Hissaria, P. B., & Nguyen, N. Q. (2025). Response to Macias et al. American Journal of Gastroenterology, 120(12), 2966. |
| 2025 | Perkins, G. B., Coates, P. T., & Fairchild, R. L. (2025). Out of chaos, comes tolerance: targeting the T cells driving antibody-mediated rejection. Kidney International, S0085-2538(25)00584-8. |
| 2025 | Robertson, H., & Perkins, G. B. (2025). Adopting a wider view: factoring blood, biopsy, and urine into kidney transplant outcomes. Kidney International, 108(5), 745-748. |
| 2024 | Perkins, G. B. (2024). Biopsy before transplant: optimizing allocation or fueling discard?. Kidney International, 106(6), 1036-1037. Scopus1 WoS1 Europe PMC1 |
| 2024 | Perkins, G. B., Zuiani, J. D., & Coates, P. T. (2024). The innate immune cells at the heart of kidney allograft rejection. Kidney International, 106(3), 348-350. |
| 2024 | Callisto, A., Perkins, G. B., Troelnikov, A., Mhatre, S., Hissaria, P., & Smith, W. (2024). Prevention of exercise-induced anaphylaxis by ibrutinib.. The journal of allergy and clinical immunology. In practice, 12(9), S2213-2198(24)00567-1. Scopus1 WoS1 Europe PMC1 |
| 2024 | Singer, J., Tunbridge, M. J., Shi, B., Perkins, G. B., Chai, C. S., Salehi, T., . . . Chadban, S. J. (2024). Dietary Inulin to Improve SARS-CoV-2 Vaccine Response in Kidney Transplant Recipients: The RIVASTIM-Inulin Randomised Controlled Trial. Vaccines, 12(6), 608-1-608-20. Scopus5 WoS4 Europe PMC3 |
| 2024 | Lim, A. H. W., Ngoi, B., Perkins, G. B., Wong, S., Whitelock, G., Hurtado, P., . . . Nguyen, N. Q. (2024). Outcomes of serum food-specific immunoglobulin G₄ to guide elimination diet in patients with eosinophilic esophagitis. The American journal of gastroenterology, 119(6), 1066-1073. Scopus15 WoS12 Europe PMC10 |
| 2024 | Baig, M., Nanjappa, N. C., Perkins, G. B., Di Lernia, R., Thiruvenkatarajan, V., & Hissaria, P. (2024). Basophil activation test in the diagnostic workup of perioperative anaphylaxis due to neuromuscular blocking agents: A case series and implications for practice. Anaesthesia and Intensive Care, 52(4), 256-263. Scopus1 WoS1 |
| 2024 | Perkins, G. B., Tunbridge, M. J., Hurtado, P. R., Zuiani, J., Mhatre, S., Yip, K. H., . . . Hissaria, P. (2024). PEGylated liposomes for diagnosis of polyethylene glycol allergy. Journal of Allergy and Clinical Immunology, 154(2), 503-507. Scopus10 WoS10 Europe PMC8 |
| 2024 | Norton, T., Lynn, M. A., Rossouw, C., Abayasingam, A., Perkins, G., Hissaria, P., . . . Lynn, D. J. (2024). B and T cell responses to the BNT162b2 COVID-19 mRNA vaccine are not impaired in germ-free or antibiotic-treated mice. Gut, 73(7), 1222-1224. Scopus5 WoS5 Europe PMC5 |
| 2023 | Montarello, N. L., Wong, H. Z., Jeffries, A., Perkins, G. B., Hissaria, P., Stokes, M. B., . . . Bradley, J. (2023). Pfizer BNT 162b2 COVID-19 vaccine–induced fulminant myopericarditis: A case study. Critical Care and Resuscitation, 25(3), 155-157. Scopus1 WoS1 Europe PMC1 |
| 2023 | Stoler, S., van Hal, S. J., Chadban, S., Le, T., Torzillo, P., Scarlato, R. -M., . . . Marinelli, T. (2023). Protracted COVID-19 pneumonitis early post-ABO incompatible kidney transplantation: Management considerations and the role of whole genome sequencing.. Nephrology (Carlton), 28(11), 639-643. Scopus1 WoS2 Europe PMC1 |
| 2023 | Zhang, W., Kedzierski, L., Chua, B. Y., Mayo, M., Lonzi, C., Rigas, V., . . . Christensen, B. (2023). Robust and prototypical immune responses toward COVID-19 vaccine in First Nations peoples are impacted by comorbidities.. Nature Immunology, 24(6), 966-978. Scopus21 WoS21 Europe PMC23 |
| 2023 | Asare, P. F., Hurtado, P. R., Tran, H. B., Perkins, G. B., Roscioli, E., & Hodge, S. (2023). Reduction in Rubicon by cigarette smoke is associated with impaired phagocytosis and occurs through lysosomal degradation pathway. Clinical and Experimental Medicine, 23(7), 4041-4055. Scopus4 WoS4 Europe PMC4 |
| 2023 | Alcheikh, A., Perkins, G. B., Pucar, P. A., Cecchin, A., Chai, C. S., Tunbridge, M., . . . Ross, D. M. (2023). Humoral and cellular immunity to SARS-CoV-2 Ancestral and Omicron BA.5 variants following vaccination in myelofibrosis patients.. Blood Cancer J, 13(1), 4 pages. Scopus3 WoS3 Europe PMC2 |
| 2023 | Perkins, G. B., Grey, S. T., & Coates, P. T. (2023). Taking the A(llorecognition) train: connecting passenger T cells to DSA. Kidney International, 103(2), 246-248. |
| 2023 | Sim, B. Z., Sim, B. L., Tunbridge, M. J., Perkins, G. B., Chai, C. S., & Coates, P. T. (2023). SARS-CoV-2 seropositivity in renal transplant patients administered intravenous immunoglobulin. Transplant Infectious Disease, 25(3), 2 pages. Scopus2 WoS1 |
| 2023 | Perkins, G. B., & Fairchild, R. L. (2023). Linking donor-specific antibody generation with natural killer cells in antibody-mediated kidney graft rejection. Kidney International, 104(4), 644-646. |
| 2023 | Bell, S., Perkins, G. B., Anandh, U., & Coates, P. T. (2023). COVID and the Kidney: An Update. Seminars in Nephrology, 43(5), 12 pages. Scopus10 WoS8 Europe PMC6 |
| 2022 | Perkins, G. B., Hurtado, P. R., & Hissaria, P. (2022). Basophil reactivity to BNT162b2 in COVID-19 convalescence. Allergy European Journal of Allergy and Clinical Immunology, 77(12), 3704-3705. Scopus2 WoS1 Europe PMC2 |
| 2022 | Singer, J., Tunbridge, M., Perkins, G. B., Salehi, T., Ying, T., Wu, H., . . . Chadban, S. J. (2022). Rapamycin and inulin for third-dose vaccine response stimulation (RIVASTIM): Inulin - Study protocol for a pilot, multicentre, randomised, double-blinded, controlled trial of dietary inulin to improve SARS-CoV-2 vaccine response in kidney transplant recipients. BMJ Open, 12(12), 10 pages. Scopus9 WoS9 Europe PMC5 |
| 2022 | Ali, S. B., Perkins, G., Ryoo, D., Lee, M., Tunbridge, M., Yuson, C., . . . Le, T. T. (2022). AstraZeneca ChAdOx1-S COVID-19 vaccine can be safely administered in patients with EDTA allergy. Allergy, Asthma and Clinical Immunology, 18(1), 4 pages. Scopus4 WoS4 Europe PMC4 |
| 2022 | Perkins, G. B., Tunbridge, M., Salehi, T., Chai, C. S., Kireta, S., Johnston, J., . . . Coates, P. T. (2022). Concurrent vaccination of kidney transplant recipients and close household cohabitants against COVID-19. Kidney International, 101(5), 1077-1080. Scopus11 WoS10 Europe PMC10 |
| 2022 | Tunbridge, M., Perkins, G., Lee, M., Salehi, T., Yuson, C., Le, A., . . . Hissaria, P. (2022). COVID vaccination can be completed in subjects with a history of allergic reactions to the vaccines or their components - experience from a specialist clinic in South Australia.. Intern Med J, 52(11), 1884-1890. Scopus3 WoS2 Europe PMC2 |
| 2022 | Tunbridge, M., Perkins, G. B., Singer, J., Salehi, T., Ying, T., Grubor-Bauk, B., . . . Coates, P. T. (2022). Rapamycin and inulin for booster vaccine response stimulation (RIVASTIM)-rapamycin: study protocol for a randomised, controlled trial of immunosuppression modification with rapamycin to improve SARS-CoV-2 vaccine response in kidney transplant recipients.. Trials, 23(1), 780-1-780-12. Scopus7 WoS7 Europe PMC5 |
| 2021 | Hope, C. M., Huynh, D., Wong, Y. Y., Oakey, H., Perkins, G. B., Nguyen, T., . . . Barry, S. C. (2021). Optimization of blood handling and peripheral blood mononuclear cell cryopreservation of low cell number samples. International Journal of Molecular Sciences, 22(17), 9129-1-9129-19. Scopus22 WoS20 Europe PMC19 |
| 2021 | Asare, P. F., Tran, H. B., Hurtado, P. R., Perkins, G. B., Nguyen, P., Jersmann, H., . . . Hodge, S. (2021). Inhibition of LC3-associated phagocytosis in COPD and in response to cigarette smoke. Therapeutic Advances in Respiratory Disease, 15, 17534666211039769-1-17534666211039769-15. Scopus21 WoS19 Europe PMC18 |
| 2021 | Troelnikov, A., Perkins, G., Yuson, C., Ahamdie, A., Balouch, S., Hurtado, P. R., & Hissaria, P. (2021). Basophil reactivity to BNT162b2 is mediated by PEGylated lipid nanoparticles in patients with PEG allergy. Journal of Allergy and Clinical Immunology, 148(1), 91-95. Scopus84 WoS84 Europe PMC65 |
| 2021 | Perkins, G., Troelnikov, A., & Hissaria, P. (2021). In reply. Journal of Allergy and Clinical Immunology, 148(3), 902-903. Scopus1 WoS1 Europe PMC1 |
| 2021 | Perkins, G. B., Kim, J., & Coates, P. T. (2021). Going rogue: how autoantibodies become pathogenic. Kidney International, 99(4), 800-802. Scopus1 WoS1 |
| 2021 | Zidan, A. A., Al Hawwas, M., Perkins, G. B., Mourad, G. M., Stapledon, C. J. M., Bobrovskaya, L., . . . Hurtado, P. R. (2021). Characterization of urine stem cell-derived extracellular vesicles reveals B cell stimulating cargo. International Journal of Molecular Sciences, 22(1), 1-21. Scopus21 WoS19 Europe PMC18 |
| 2021 | Zidan, A. A., Perkins, G., Al Hawwas, M., Elhossiny, A., Yang, J., Bobrovskaya, L., . . . Hurtado, P. R. (2021). Urine stem cells are equipped to provide B cell survival signals. Stem Cells, 39(6), 803-818. Scopus7 WoS6 Europe PMC7 |
| 2020 | Kim, J., Hope, C. M., Gantumur, N., Perkins, G. B., Stead, S. O., Yue, Z., . . . Coates, P. T. (2020). Encapsulation of human natural and induced regulatory T-cells in IL-2 and CCL1 supplemented alginate-GelMA hydrogel for 3D bioprinting. Advanced Functional Materials, 30(15), 2000544-1-2000544-17. Scopus42 WoS35 |
| 2020 | Kim, J., Perkins, G. B., & Coates, P. T. (2020). Evolutionary immunology: how your ancestry can affect your kidney transplant. Kidney International, 98(1), 45-47. Scopus2 WoS2 Europe PMC2 |
| 2020 | Kim, J., Hope, C. M., Perkins, G. B., Stead, S. O., Scaffidi, J. C., Kette, F. D., . . . Coates, P. T. (2020). Rapamycin and abundant TCR stimulation are required for the generation of stable human induced regulatory T cells. Clinical & Translational Immunology, 9(12), 1-20. Scopus9 WoS9 Europe PMC7 |
| 2019 | Jeffs, L., Peh, C., Nelson, A., Tan, P., Davey, E., Chappell, K., . . . Hurtado, P. (2019). IgM ANCA in healthy individuals and in patients with ANCA-associated vasculitis. Immunologic Research, 67(4-5), 325-336. Scopus7 WoS6 Europe PMC4 |
| Year | Citation |
|---|---|
| 2025 | Zuiani, J., Wu, D., Roach, M., Putoczki, T., Saad, M., Martelotto, L., . . . Coates, T. (2025). UNDERSTANDING HEREDITARY PANCREATITIS: PATIENT ORGANOIDS COMPLLIMENT SPATIAL TRANSCRIPTOMIC ANALYSIS. In TRANSPLANTATION Vol. 109 (pp. 50). ITALY, Pisa: LIPPINCOTT WILLIAMS & WILKINS. DOI |
| 2024 | Sheng Chai, C., Boord Perkins, G., Tunbridge, M., Hope, C., Yeow, A., Salehi, T., . . . Coates, T. (2024). Rapamycin diversifies SARS-CoV-2 specific T cell memory with stem cell phenotype in immunosuppressed kidney transplant recipients.. In TRANSPLANTATION Vol. 108 (pp. 1 page). TURKEY, Istanbul: LIPPINCOTT WILLIAMS & WILKINS. DOI |
| 2024 | Perkins, G., Tunbridge, M. J., Singer, J., Sheng Chai, C., Shi, B., Ying, T., . . . Coates Ao, P. T. H. (2024). Outcomes of the RIVASTIM: Rapamycin randomized controlled trial of immunosuppression modification to improve vaccine responses in kidney transplant recipients. In TRANSPLANTATION Vol. 108 (pp. 1 page). LIPPINCOTT WILLIAMS & WILKINS. DOI |
| 2024 | Zuiani, J., Wu, D., Perkins, G., Drogemuller, C., & Coates, T. (2024). Characterising pancreatic organoids from hereditary pancreatitis patients. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 39 (pp. 58). WILEY. |
| 2024 | Chai, C. S., Perkins, G. B., Tunbridge, M., Hope, C., Yeow, A., Salehi, T., . . . Coates, T. (2024). Rapamycin diversifies SARS-CoV-2 specific T cell memory with stem cell phenotype in immunosuppressed kidney transplant recipients. In Abstracts of the 30th International Congress of The Transplantation-Society (TTS, 2024) as published in Transplantation Vol. 108 (pp. 89). Istanbul, Turkey: Lippincott, Williams & Wilkins. |
| 2024 | Perkins, G., Tunbridge, M. J., Singer, J., Chai, C. S., Shi, B., Ying, T., . . . Coates A O, P. T. H. (2024). Outcomes of the RIVASTIM: Rapamycin randomized controlled trial of immunosuppression modification to improve vaccine responses in kidney transplant recipients. In TRANSPLANTATION Vol. 108 (pp. 349). TURKEY, Istanbul: LIPPINCOTT WILLIAMS & WILKINS. |
| 2023 | Lim, A. H., Ngoi, B., Hissaria, P., Perkins, G., Wong, S., Hurtado, P. R., . . . Nguyen, N. Q. (2023). SERUM FOOD-SPECIFIC IGG4-LED TARGETED ELIMINATION DIET IN PATIENTS WITH EOSINOPHILIC ESOPHAGITIS. In GASTROENTEROLOGY Vol. 164 (pp. S90). IL, Chicago: W B SAUNDERS CO-ELSEVIER INC. |
| 2023 | Zuiani, J., Wu, D., Perkins, G., Grey, S., Drogemuller, C., & Coates, P. T. (2023). Growing pancreatic organoids for hereditary pancreatitis. In Abstracts of the IPITA-IXA-CTRMS Joint Congress 2023, as published in Transplantation Vol. 107 (pp. 35). San Diego, CA, USA: Lippincott Williams & Wilkins. DOI |
| 2023 | Chai, C., Perkins, G., Yeow, A., Masavuli, M., Mekonnen, Z., Santos, R., . . . Coates, T. (2023). Optimising Adjuvant Effect of Rapamycin to Improve the Immunogenicity of Covid-19 Vaccines. In AMERICAN JOURNAL OF TRANSPLANTATION Vol. 23 (pp. S605). CA, San Diego: ELSEVIER SCIENCE INC. |
| 2022 | Lim, A., Hissaria, P., Perkins, G., Wong, S., Whitelock, G., Le, T. -T., . . . Nguyen, N. (2022). Food-specific serum IgG4 in the assessment and management of eosinophilic esophagitis: Its role in guiding food-elimination diet. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 37 (pp. 191-192). WILEY. |
| 2022 | Tunbridge, M. J., Perkins, G., Salehi, T., Grubor-Bauk, B., Sim, B., Ying, T., . . . Coates, P. T. (2022). A Prospective Randomised, Controlled Trial Switching Sirolimus for Mycophenolate to Enhance Immunological Responses to Third Dose COVID-19 Vaccination in Kidney Transplant Recipients with Poor Baseline Humoral Immunity. In AMERICAN JOURNAL OF TRANSPLANTATION Vol. 22 (pp. 1095). ELECTR NETWORK: WILEY. |
| 2022 | Singer, J., Tunbridge, M., Salehi, T., Perkins, G., Grubnor-Bauk, B., Sim, B., . . . Chadban, S. J. (2022). A Randomized, Controlled, Double-Blind Trial of Inulin to Boost Response to a Third COVID-19 Vaccine Dose in Kidney Transplant Recipients.. In AMERICAN JOURNAL OF TRANSPLANTATION Vol. 22 (pp. 736). ELECTR NETWORK: WILEY. |
| 2022 | Perkins, G. B., Tunbridge, M., Salehi, T., Chai, C., Hope, C. M., Garcia-Valtanen, P., . . . Coates, P. (2022). Sirolimus Use is Associated with an Improved Immune Response to COVID-19 Vaccination in Kidney Transplant Recipients. In AMERICAN JOURNAL OF TRANSPLANTATION Vol. 22 (pp. 873). WILEY. |
| 2022 | Perkins, G., Tunbridge, M., Zuiani, J., Ryoo, D., Ahmadie, A., Kette, F., . . . Hissaria, P. (2022). PEGYLATED LIPOSOMAL MEDICATIONS ARE HIGHLY EFFECTIVE REAGENTS FOR THE DIAGNOSIS OF POLYETHYLENE GLYCOL ALLERGY. In INTERNAL MEDICINE JOURNAL Vol. 52 (pp. 7). WILEY. |
| 2022 | Perkins, G., Tunbridge, M., Salehi, T., Chai, C. S., Hope, C. M., Garcia-Valtanen, P., . . . Coates, A. O. T. (2022). MTOR Inhibitors Promote Highly Functional T Cell Immunity in Kidney Transplant Recipients Vaccinated Against COVID-19. In TRANSPLANTATION Vol. 106 (pp. S223). ELECTR NETWORK: LIPPINCOTT WILLIAMS & WILKINS. |
| 2021 | Asare, P., Roscioli, E., Hurtado, P., Tran, H., & Hodge, S. (2021). INHIBITION OF LC3-ASSOCIATED PHAGOCYTOSIS (LAP) IN COPD AND IN RESPONSE TO CIGARETTE SMOKE. In RESPIROLOGY Vol. 26 (pp. 21-22). WILEY. |
| 2021 | Tunbridge, M., Perkins, G., Salehi, T., Lee, M., Ryoo, D., Ahmadie, A., . . . Hissaria, P. (2021). EARLY RESULTS OF AN <i>IN VIVO</i> AND <i>IN VITRO</i> ALLERGY TESTING PROTOCOL FOR COVID-19 VACCINATIONS. In INTERNAL MEDICINE JOURNAL Vol. 51 (pp. 14). WILEY. |
| 2020 | Kim, J., Hope, C. M., Scaffidi, J. C., Stead, S. O., Perkins, G. B., Kette, F. D., . . . Coates, P. T. (2020). GENERATION OF STABLE HUMAN INDUCED REGULATORY T-CELLS REQUIRES OPTIMAL RAPAMYCIN CONCENTRATION AND TCR STIMULATION. In TRANSPLANTATION Vol. 104 (pp. S206). ELECTR NETWORK: LIPPINCOTT WILLIAMS & WILKINS. |
| 2020 | Stead, S. O., Kim, J., Kette, F. D., Perkins, G. B., & Coates, P. T. H. (2020). SIRNA GENE KNOCKDOWN WITH FUNCTIONALISED POROUS SILICON NANOPARTICLES. In TRANSPLANTATION Vol. 104 (pp. S158). ELECTR NETWORK: LIPPINCOTT WILLIAMS & WILKINS. WoS1 |
| 2020 | Perkins, G., Hope, C. M., Kim, J., Kette, F., Stead, S., Coates, P. T. H., & Hurtado, P. R. (2020). IL-4 REGULATES THE SECRETION OF IL-10 BY HUMAN B CELLS. In TRANSPLANTATION Vol. 104 (pp. S151). ELECTR NETWORK: LIPPINCOTT WILLIAMS & WILKINS. |
| Year | Citation |
|---|---|
| 2023 | Perkins, G., Tunbridge, M., Chai, C. S., Hope, C., Yeow, A. E. L., Salehi, T., . . . Coates, T. (2023). mTOR inhibition improves the formation of functional T cell memory following COVID-19 vaccination of kidney transplant recipients. DOI Europe PMC2 |
| 2023 | Perkins, G., Hope, C., Chai, C. S., Tunbridge, M., Sterling, S., Webb, K., . . . Hissaria, P. (2023). Immune profiling of COVID-19 vaccine responses in people with multiple sclerosis on B cell-depleting therapy. DOI |
As Chief Investigator, I have received >$2M in competitive research funding and salary support.
2025 Australasian Society of Clinical Immunology and Allergy (ASCIA)/Allergy and Immunology Foundation of Australasia (AIFA) – Chief Investigator A
Single-cell imaging of the peripheral immune response to venom immunotherapy – $10,000
2025 University of Adelaide – Chief Investigator A
Building Research Leaders Grant Scheme – $49,550
2024-27 Medical Research Futures Fund (MRFF) – Chief Investigator
Repurposing mTOR inhibitors to boost vaccine responses in the immunocompromised and elderly – $1,319,883
2024/25 Health Services Charitable Gifts Board (HSCGB) – Chief Investigator
Clinical Project Grant – $20,565
2024 University of Adelaide – Chief Investigator A
Equipment Grant – $9,311
2024 Kidney, Transplant & Diabetes Research Australia (KTDRA) – Chief Investigator C
Pre-clinical screening of GAD65 CAR-Tregs as a Novel Therapy for Type 1 Diabetes – $27,200
2023-25 Royal Adelaide Hospital Research Committee & Health Services Charitable Gifts Board
Mary Overton Early Career Research Fellowship – $322,000
2023/24 Health Services Charitable Gifts Board (HSCGB) – Chief Investigator
Clinical Project Grant – $49,404
2022/23 Health Services Charitable Gifts Board (HSCGB) – Chief Investigator
Clinical Project Grant – $49,404
2021/22 Health Services Charitable Gifts Board (HSCGB) – Chief Investigator
Clinical Project Grant – $46,512
2019 Research Training Program – Scholarship
PhD Stipend – $58,780
2018 University of Adelaide – Scholarship
Master of Philosophy (No Honours) Scholarship – $94,616 competitive scholarship awarded to 12 students university-wide.
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2025 | Co-Supervisor | Repurposing mTOR inhibitors to improve immunological response to vaccination in older adults. | Doctor of Philosophy | Doctorate | Full Time | Ms Deborah Pratt |
| 2025 | Co-Supervisor | Repurposing mTOR inhibitors to improve immunological response to vaccination in older adults. | Doctor of Philosophy | Doctorate | Full Time | Ms Deborah Pratt |
| 2024 | Co-Supervisor | Characterisation of Pancreatic Organoids in Hereditary Pancreatitis and Normal Individuals | Doctor of Philosophy | Doctorate | Part Time | Mr James Daniel Zuiani |
| 2024 | Co-Supervisor | Modulation of the foreign antigen response in solid organ transplantation | Doctor of Philosophy | Doctorate | Full Time | Dr Matthew Jack Tunbridge |
| 2024 | Co-Supervisor | To develop and validate an in vitro diagnostic system to assess insect allergy and monitor outcomes of venom immunotherapy | Master of Philosophy (Medical Science) | Master | Full Time | Mrs Shweta Mhatre |
| 2024 | Co-Supervisor | To develop and validate an in vitro diagnostic system to assess insect allergy and monitor outcomes of venom immunotherapy | - | Master | Full Time | Mrs Shweta Mhatre |
| 2024 | Co-Supervisor | Modulation of the foreign antigen response in solid organ transplantation | Doctor of Philosophy | Doctorate | Full Time | Dr Matthew Jack Tunbridge |
| 2024 | Co-Supervisor | Characterisation of Pancreatic Organoids in Hereditary Pancreatitis and Normal Individuals | Doctor of Philosophy | Doctorate | Full Time | Mr James Daniel Zuiani |
| 2023 | Co-Supervisor | The Effect of Sirolimus on Enhancing COVID-19 Vaccine Response in Transplant Recipients | Doctor of Philosophy | Doctorate | Full Time | Mr Cheng Sheng Chai |
| 2023 | Co-Supervisor | The Effect of Sirolimus on Enhancing COVID-19 Vaccine Response in Transplant Recipients | Doctor of Philosophy | Doctorate | Full Time | Mr Cheng Sheng Chai |
| Date | Role | Research Topic | Location | Program | Supervision Type | Student Load | Student Name |
|---|---|---|---|---|---|---|---|
| 2023 - ongoing | Co-Supervisor | Rapamycin as an adjuvant to enhance vaccine responses in immunocompromised individuals | University of Adelaide | - | Doctorate | - | Cheng Sheng Chai |
| 2021 - 2021 | Co-Supervisor | Immunogenicity of COVID-19 Vaccines In South Australian Kidney Transplant Recipients | University of Adelaide | - | Honours | - | Cheng Sheng Chai |
| Date | Role | Committee | Institution | Country |
|---|---|---|---|---|
| 2025 - ongoing | Member | Early Career Committee | The Transplantation Society | Canada |
| 2020 - ongoing | Co-Chair | Early Career Researcher Committee | Transplantation Society of Australia and New Zealand | Australia |
| Date | Role | Membership | Country |
|---|---|---|---|
| 2023 - ongoing | Member | Australiasian Society of Clinical Immunology and Allergy | Australia |
| 2023 - ongoing | Member | International Society of Nephrology | Belgium |
| 2019 - ongoing | Member | American Society of Transplantation | United States |
| 2019 - ongoing | Member | Australian and New Zealand Society for Immunology | Australia |
| 2018 - ongoing | Member | The Transplantation Society | Canada |
| 2018 - ongoing | Member | Transplantation Society of Australia and New Zealand | Australia |
| Date | Title | Engagement Type | Institution | Country |
|---|---|---|---|---|
| 2023 - ongoing | Social Media Representative | Scientific Community Engagement | Transplantation Society of Australia and New Zealand | Australia |
| Date | Role | Editorial Board Name | Institution | Country |
|---|---|---|---|---|
| 2024 - ongoing | Board Member | Scientific Reports | Nature Portfolio | Germany |
| 2022 - ongoing | Board Member | Kidney International | International Society of Nephrology | United States |
| Date | Office Name | Institution | Country |
|---|---|---|---|
| 2023 - ongoing | Kidney International Editorial Fellow | Kidney International | United States |
| 2023 - ongoing | Co-chair, Early Career Committee | Transplantation Society of Australia and New Zealand | Australia |
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