Dr Damian Stachura
Grant Funded Researcher A
School of Physics, Chemistry and Earth Sciences
Faculty of Sciences, Engineering and Technology
Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.
Damian graduated from The University of Adelaide in 2018 with a Bachelor of Science (Honours) in Chemistry. He then went on to complete his PhD in Medicinal Chemistry at The University of Adelaide, under the continued supervision of Prof. Andrew Abell and Dr. Thomas Avery. His work focused on the development and characterization of a novel class of antibiotics, with his thesis being awarded "The Deans Commendation for Doctoral Thesis Excellence". Damian now works as a postdoctoral researcher at The University of Adelaide on a collaborative project with MD Anderson and the NIH to develop novel therapeutics that treat neuropathic pain. He is also a member of the ARC Centre of Excellence for Nanoscale Biophotonics (CNBP) and a Scientific Network Committee member for the Institute for Photonics & Advanced Sensing (IPAS).
My research area explores the development of small molecules that inhibit enzymes associated with pathogenic bacteria. Majority of my work focuses on the design, synthesis and characterization of such molecules, with the intended goal of developing highly potent and selective inhibitors of the target enzyme.
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Appointments
Date Position Institution name 2023 - ongoing Postdoctoral Researcher The University of Adelaide -
Language Competencies
Language Competency English Can read, write, speak and understand spoken Polish Can read, speak and understand spoken -
Education
Date Institution name Country Title 2019 - 2023 The University of Adelaide Australia PhD 2018 - 2018 The University of Adelaide Australia Bachelor of Science (Honours) 2015 - 2017 University of Adelaide Australia Bachelor of Science -
Research Interests
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Journals
Year Citation 2024 Kalyvas, J. T., Wang, Y., Toronjo-Urquiza, L., Stachura, D. L., Yu, J., Horsley, J. R., & Abell, A. D. (2024). A New Gramicidin S Analogue with Potent Antibacterial Activity and Negligible Hemolytic Toxicity. Journal of Medicinal Chemistry, 67(13), 10774-10782.
Scopus3 Europe PMC12024 Stachura, D. L., Kalyvas, J. T., & Abell, A. D. (2024). New Potent Sulfonamide-Based Inhibitors of <i>S</i>. <i>aureus</i> Biotin Protein Ligase. ACS Medicinal Chemistry Letters, 15(9), 1467-1473.
2024 Avery, T. D., Li, J., Turner, D. J. L., Rasheed, M. S. U., Cherry, F. R., Stachura, D. L., . . . Grace, P. M. (2024). Site-specific drug release of monomethyl fumarate to treat oxidative stress disorders. Nature Biotechnology, 16 pages.
Europe PMC12023 Stachura, D. L., Nguyen, S., Polyak, S. W., Jovcevski, B., Bruning, J. B., & Abell, A. D. (2023). Structural Study of Potent Triazole-Based Inhibitors of <i>Staphylococcus aureus</i> Biotin Protein Ligase. ACS Medicinal Chemistry Letters, 14(3), 285-290.
Scopus1 Europe PMC12023 Kalyvas, J. T., Marina, P. F., Stachura, D. L., Horsley, J., & Abell, A. D. (2023). Smart Wearable Patches Using Light-Controlled Activation and Delivery of Photoswitchable Antimicrobial Peptides. Chemistry, 29(46), 1-8.
Scopus22022 Stachura, D. L., Nguyen, S., Polyak, S. W., Jovcevski, B., Bruning, J. B., & Abell, A. D. (2022). A New 1,2,3-Triazole Scaffold with Improved Potency against Staphylococcus aureus Biotin Protein Ligase. ACS Infectious Diseases, 8(12), 2579-2585.
Scopus5 WoS2 Europe PMC2
Damian has taught 1st, 2nd and 3rd year organic chemistry practical courses at The University of Adelaide.
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2023 Co-Supervisor The Design and Synthesis of New Antimicrobial Agents Based on Biotin Biology Doctor of Philosophy Doctorate Full Time Ms Taylah Renee Cruse
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Memberships
Date Role Membership Country 2023 - ongoing Member IPAS Scientific Network Committee Australia 2018 - ongoing Member Center for Nanoscale Biophotonics Australia 2018 - ongoing Member Institute for Photonics and Advanced Sensing Australia
Connect With Me
External Profiles
