Matthew Briggs
School of Agriculture, Food and Wine
Faculty of Sciences, Engineering and Technology
Dr Matthew Briggs is an expert in Glycomics & Lipidomics currently working as an ARC Grant-Funded Researcher (Level B) at Adelaide University under Professor Jenny Mortimer. Previously, he worked as an Associate Research Fellow at the University of Wollongong under Associate Professor Shane Ellis and as a Postdoctoral Research Associate at the University of South Australia under Professor Peter Hoffmann. Matthew received his PhD in 2018 from the University of Adelaide, along with his Honours Degree (Biochemistry) in 2014, as well as his Bachelor of Science (Molecular Biology) and Diploma of Languages (Indonesian) in 2013. Since graduating, he has published 25 scientific publications in peer reviewed journals, ranging from research articles and literature reviews to book chapters and opinion pieces. Most notably, his research has been published in Proteomics, Analytical Chemistry, Analytical and Bioanalytical Chemistry and Molecular and Cellular Proteomics. Matthew has also had the fortunate opportunity to present his work at over 15 national and international conferences, including the Annual Lorne Proteomics Symposium since 2014, the Human Proteome Organization World Congress in 2015 and 2019, and most recently, the Australasian Glycoscience Symposium. In 2019, Matthew was awarded a University of South Australia Future Industries Accelerator Mobility Grant to design and develop a novel cost-effective and time-efficient MALDI-MS workflow as a Visiting Research Associate at CSL Limited, one of the world’s largest biopharmaceutical companies. Furthermore, Matthew was awarded Best Student Paper by the Australian Society for Biochemistry and Molecular Biology, and the Institute of Photonics and Advanced Sensing in 2016 and 2017, respectively.
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Appointments
Date Position Institution name 2025 - ongoing ARC Grant-Funded Researcher (Level B) University of Adelaide 2024 - 2025 Associate Research Fellow University of Wollongong 2018 - 2024 Postdoctoral Research Associate University of South Australia -
Awards and Achievements
Date Type Title Institution Name Country Amount 2017 Award Institute for Photonics and Advanced Sensing Best Student Paper Institute of Photonics and Advanced Sensing Australia - 2016 Award Australian Society for Biochemistry and Molecular Biology Best Student Paper Australian Society for Biochemistry and Molecular Biology Australia - -
Education
Date Institution name Country Title 2015 - 2018 University of Adelaide Australia PhD 2014 - 2014 University of Adelaide Australia Bachelor of Science (Honours) 2010 - 2013 University of Adelaide Australia Bachelor of Science (Molecular Biology) 2010 - 2013 University of Adelaide Australia Diploma of Languages (Indonesian) -
Research Interests
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Journals
Year Citation 2025 Lau, D., Donnellan, L., Briggs, M., Klingler-Hoffmann, M., & Hoffmann, P. (2025). MALDI Mass Spectrometry Imaging of Metabolites in Cereal Grains and Legumes: Repurposing for Industrial Applications. Food Reviews International, 41(4), 1200-1221.
Scopus2 WoS22024 Lau, W. C. D., Donnellan, L., Briggs, M., Rupasinghe, T., Harris, J. C., Hayes, J. E., & Hoffmann, P. (2024). Sodium doping and trapped ion mobility spectrometry improve lipid detection for novel MALDI-MSI analysis of oats. Food Chemistry, 433, 1-10.
Scopus7 WoS7 Europe PMC42024 Li, C. M. Y., Briggs, M. T., Lee, Y. -R., Tin, T., Young, C., Pierides, J., . . . Fenix, K. (2024). Use of tryptic peptide MALDI mass spectrometry imaging to identify the spatial proteomic landscape of colorectal cancer liver metastases.. Clin Exp Med, 24(1), 53.
Scopus3 WoS3 Europe PMC22024 Ngai, Y. T., Briggs, M. T., Mittal, P., Young, C., Parkinson-Lawrence, E., Klingler-Hoffmann, M., . . . Hoffmann, P. (2024). Mass spectrometry imaging protocol for spatial mapping of lipids, N-glycans and peptides in murine lung tissue. Rapid Communications in Mass Spectrometry, 38(9), 19 pages.
Scopus3 WoS3 Europe PMC22023 Lee, Y. -R., Briggs, M. T., Kuliwaba, J. S., Jagiello, J., Anderson, P. H., & Hoffmann, P. (2023). Complex-Type <i>N</i>-Glycans Are Associated with Cartilage Degeneration within Different Loading Sites of the Tibial Plateau for Knee Osteoarthritis Patients. Journal of Proteome Research, 22(8), 2694-2702.
Scopus3 WoS3 Europe PMC32023 Lee, Y. -R., Briggs, M. T., Kuliwaba, J. S., Jagiello, J., Anderson, P. H., & Hoffmann, P. (2023). High-Resolution <i>N</i>-Glycan MALDI Mass Spectrometry Imaging of Subchondral Bone Tissue Microarrays in Patients with Knee Osteoarthritis. Analytical Chemistry, 95(34), 12575-12992.
Scopus3 WoS3 Europe PMC52022 Lee, Y. -R., Briggs, M. T., Young, C., Condina, M. R., Kuliwaba, J. S., Anderson, P. H., & Hoffmann, P. (2022). Mass spectrometry imaging spatially identifies complex-type N-glycans as putative cartilage degradation markers in human knee osteoarthritis tissue. Analytical and Bioanalytical Chemistry, 414(26), 7597-7607.
Scopus9 WoS9 Europe PMC62022 McNab, J. M., Briggs, M. T., Williamson, J. E., Hoffmann, P., Rodriguez, J., & Karuso, P. (2022). Structural Characterization and Spatial Mapping of Tetrodotoxins in Australian Polyclads. Marine Drugs, 20(12), 15 pages.
Scopus6 WoS6 Europe PMC22021 Dilmetz, B. A., Lee, Y. R., Condina, M. R., Briggs, M., Young, C., Desire, C. T., . . . Hoffmann, P. (2021). Novel technical developments in mass spectrometry imaging in 2020: A mini review. Analytical Science Advances, 2(3-4), 225-237.
Scopus23 WoS22 Europe PMC202021 Lee, Y. R., Briggs, M. T., Kuliwaba, J. S., Anderson, P. H., Condina, M. R., & Hoffmann, P. (2021). Gelatin-coated indium tin oxide slides improve human cartilage-bone tissue adherence and N-glycan signal intensity for mass spectrometry imaging. Analytical and Bioanalytical Chemistry, 413(10), 2675-2682.
Scopus12 WoS13 Europe PMC82021 Mittal, P., Briggs, M., Klingler-Hoffmann, M., Kaur, G., Packer, N. H., Oehler, M. K., & Hoffmann, P. (2021). Altered N-linked glycosylation in endometrial cancer. Analytical and Bioanalytical Chemistry, 413(10), 2721-2733.
Scopus19 WoS19 Europe PMC172021 Young, C., Condina, M. R., Briggs, M. T., Moh, E. S. X., Kaur, G., Oehler, M. K., & Hoffmann, P. (2021). In-House Packed Porous Graphitic Carbon Columns for Liquid Chromatography-Mass Spectrometry Analysis of N-Glycans. Frontiers in Chemistry, 9, 9 pages.
Scopus16 WoS14 Europe PMC102020 Lee, Y. R., Briggs, M. T., Condina, M. R., Puddy, H., Anderson, P. H., Hoffmann, P., & Kuliwaba, J. S. (2020). Mass spectrometry imaging as a potential tool to investigate human osteoarthritis at the tissue level. International Journal of Molecular Sciences, 21(17), 6414-1-6414-13.
Scopus14 WoS12 Europe PMC112019 Briggs, M. T., Condina, M. R., Klingler-Hoffmann, M., Arentz, G., Everest-Dass, A. V., Kaur, G., . . . Hoffmann, P. (2019). Translating N-Glycan Analytical Applications into Clinical Strategies for Ovarian Cancer. Proteomics - Clinical Applications, 13(3), 1-5.
Scopus22 WoS16 Europe PMC102019 Briggs, M. T., Condina, M. R., Ho, Y. Y., Everest-Dass, A. V., Mittal, P., Kaur, G., . . . Hoffmann, P. (2019). MALDI mass spectrometry imaging of early- and late-stage serous ovarian cancer tissue reveals stage-specific N-glycans. Proteomics, 19(21-22), 1800482-1-1800482-11.
Scopus52 WoS46 Europe PMC382019 Horan, M. P., Hoffmann, P., Briggs, M. T., Condina, M., Herbert, S., Ito, J., . . . Badrick, T. (2019). An external quality assurance trial to assess mass spectrometry protein testing facilities for identifying multiple human peptides. Analytical and Bioanalytical Chemistry, 411(25), 6575-6581.
Scopus2 WoS12019 Chatterjee, S., Lee, L. Y., Kawahara, R., Abrahams, J. L., Adamczyk, B., Anugraham, M., . . . Thaysen-Andersen, M. (2019). Protein Paucimannosylation Is an Enriched N-Glycosylation Signature of Human Cancers. Proteomics, 19(21-22), 13 pages.
Scopus54 WoS61 Europe PMC452019 Condina, M. R., Mittal, P., Briggs, M. T., Oehler, M. K., Klingler-Hoffmann, M., & Hoffmann, P. (2019). Egg white as a quality control in matrix assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI).. Analytical chemistry, 91(23), 14846-14853.
Scopus13 WoS14 Europe PMC82018 Gustafsson, O. J. R., Briggs, M. T., Condina, M. R., Winderbaum, L. J., Pelzing, M., McColl, S. R., . . . Hoffmann, P. (2018). Raw N-glycan mass spectrometry imaging data on formalin-fixed mouse kidney. Data in Brief, 21, 185-188.
Scopus4 WoS3 Europe PMC32017 Briggs, M., Ho, Y., Kaur, G., Oehler, M., Everest-Dass, A., Packer, N., & Hoffmann, P. (2017). N-Glycan matrix-assisted laser desorption/ionization mass spectrometry imaging protocol for formalin-fixed paraffin-embedded tissues. Rapid Communications in Mass Spectrometry, 31(10), 825-841.
Scopus25 WoS23 Europe PMC192016 Briggs, M., Kuliwaba, J., Muratovic, D., Everest-Dass, A., Packer, N., Findlay, D., & Hoffmann, P. (2016). MALDI mass spectrometry imaging of N-glycans on tibial cartilage and subchondral bone proteins in knee osteoarthritis. Proteomics, 16(11-12), 1736-1741.
Scopus43 WoS41 Europe PMC362016 Everest-Dass, A., Briggs, M., Kaur, G., Oehler, M., Hoffmann, P., & Packer, N. (2016). N-glycan MALDI imaging mass spectrometry on formalin-fixed paraffin-embedded tissue enables the delineation of ovarian cancer tissues. Molecular and Cellular Proteomics, 15(9), 3003-3016.
Scopus106 WoS101 Europe PMC782015 Gustafsson, O., Briggs, M., Condina, M., Winderbaum, L., Pelzing, M., McColl, S., . . . Hoffmann, P. (2015). MALDI imaging mass spectrometry of N-linked glycans on formalin-fixed paraffin-embedded murine kidney. Analytical and Bioanalytical Chemistry, 407(8), 2127-2139.
Scopus75 WoS71 Europe PMC64 -
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