Prof Sarah Vreugde
Externally-Funded Research Professor
School of Medicine
College of Health
Professor Sarah Vreugde Director of Research: ENT Surgery The Department of Otolaryngology, Head and Neck Surgery at The Queen Elizabeth Hospital is committed to excellence in translational research and education. Research in our department is focused mainly on understanding the pathogenesis of chronic rhinosinusitis (CRS), using a multidisciplinary approach, aimed at identifying new diagnostic/prognostic markers and treatment strategies to the benefit of our patients. Research projects cover all aspects of rhinological research from pathophysiological aspects of CRS to the identification and validation of new treatment strategies in vitro and in vivo, bringing research from bench to bedside.Our Department of ENT has an excellent track record of Honours and Higher degree supervision with a 100% completion rate. Professor PJ Wormald was recognized for “Excellence in Research Supervision” by The University of Adelaide in 2013. We are always interested in students that have exceptional motivation and are passionate about research and in return we provide them with full support in terms of research supervision direction.
Projects in my laboratory are focused on diseases of the ear, nose and throat. In particular, my research is focused on pathophysiological aspects of chronic rhinosinusitis, aimed at the identification and validation of new diagnostic and treatment strategies in vitro and in vivo. Projects range from defining molecular mechanisms and microbial determinants of chronic inflammation to the validation of anti-bacterial and wound-healing compounds in vitro and in vivo.
| Date | Position | Institution name |
|---|---|---|
| 2024 - ongoing | Professor | University of Adelaide |
| 2017 - 2023 | Associate Professor | The University of Adelaide |
| 2013 - 2016 | Senior Scientist | The University of Adelaide |
| 2008 - 2011 | Patent Examiner | European Patent Office |
| 2003 - 2006 | Post-doctoral research scientist | Istituto Scientifico San Raffaele (IRCCS), Milan |
| 2003 - 2006 | Consultant | San Raffaele Hospital, Milan |
| Language | Competency |
|---|---|
| Dutch; Flemish | Can read, write, speak, understand spoken and peer review |
| English | Can read, write, speak, understand spoken and peer review |
| French | Can read, write, speak, understand spoken and peer review |
| German | Can read, speak and understand spoken |
| Hebrew | Can speak and understand spoken |
| Italian | Can read, write, speak, understand spoken and peer review |
| Date | Institution name | Country | Title |
|---|---|---|---|
| 1998 - 2002 | Tel Aviv University | Israel | PhD |
| 1994 - 2000 | Free University Brussels | Belgium | ENT Specialisation |
| 1994 | Free University Brussels | Belgium | MD |
| Year | Citation |
|---|---|
| 2026 | Awad, M., Bouras, G., Feizi, S., Grigson, S. R., Wormald, P. J., Psaltis, A. J., & Vreugde, S. (2026). LicD-mediated cell wall decoration governs phage sensitivity in Enterococcus faecalis clinical isolates. Microbiological Research, 302, 14 pages. |
| 2025 | MMed, X. S., Ramezanpour, M., Hall, J., Barry, E., Psaltis, A. J., Wormald, P. -J., & Vreugde, S. (2025). Patient-Specific Coculture of S. aureus and P. aeruginosa Enhances Epithelial Barrier Disruption and Virulence in CRS.. Int Forum Allergy Rhinol, 12 pages. |
| 2025 | Candy, N. G., Barry, E. F., Tomatis, V. M., Patel, S., Miller, J., Ovenden, C., . . . Wormald, P. J. (2025). Phase I trial to evaluate safety of Deferiprone-Chitogel to prevent epidural fibrosis in lumbar spine surgery. European Spine Journal, 10 pages. |
| 2025 | Pourmehran, O., Psaltis, A. J., Vreugde, S., Zarei, K., Shang, Y., Inthavong, K., & Wormald, P. -J. (2025). Evaluating Nebulisation and Nasal Irrigation Efficiency in Post-Operative Chronic Rhinosinusitis Patients Through Computational Fluid Dynamics Simulation. Computer Methods and Programs in Biomedicine, 264, 108697-1-108697-18. Scopus3 WoS3 Europe PMC2 |
| 2025 | Feizi, S., Cooksley, C. M., Reyne, N., Boog, B., Finnie, J., Shaghayegh, G., . . . Vreugde, S. (2025). An immunocompetent rat model of Mycobacterium abscessus multinodular granulomatous lung infection. Tuberculosis, 152, 102629-1-102629-8. Scopus2 WoS2 Europe PMC1 |
| 2025 | Hao, N., Vreugde, S., Fitridge, R., & Shearwin, K. E. (2025). Complete genome sequence of Anaerococcus sp. strain AH8042_DFU013_CI05 isolated from a diabetes-related foot ulcer.. Microbiology Resource Announcements, 14(4), e0132624-1-e0132624-4. |
| 2025 | Fong, S. A., Bouras, G., Houtak, G., Nepal, R., Feizi, S., Morales, S., . . . Vreugde, S. (2025). Genomic variation in Pseudomonas aeruginosa clinical respiratory isolates with de novo resistance to a bacteriophage cocktail. Microbiology Spectrum, 13(5), e02149-24-1-e02149-24-22. |
| 2025 | Paramasivan, S., Bassiouni, A., Bokulich, N. A., Ramezanpour, M., Cooksley, C., Caporasso, J. G., . . . Vreugde, S. (2025). Tertiary Lymphoid Organs Are Associated With Bacterial Dysbiosis in Chronic Rhinosinusitis. International Forum of Allergy and Rhinology, 15(8), 869-872. |
| 2025 | Burdon, I., Bouras, G., Fenix, K., Yeo, K., Connell, J., Cooksley, C., . . . Psaltis, A. J. (2025). Metagenomics or Metataxonomics: Best Practice Methods to Uncover the Sinus Microbiome. International Forum of Allergy and Rhinology, 15(9), 989-992. Europe PMC1 |
| 2025 | Hall, J., Psaltis, A., Vreugde, S., Feizi, S., Chuah, Y., Alsharifi, M., & Ramezanpour, M. (2025). Effects of influenza A infection on liberation of bacteria from biofilms and inflammatory response in an in vitro model of chronic rhinosinusitis.. Microbiology (Reading), 171(8), 9 pages. |
| 2025 | Nepal, R., Houtak, G., Bouras, G., Feizi, S., Shaghayegh, G., Shearwin, K., . . . Vreugde, S. (2025). A φSa3int (NM3) Prophage Domestication in Staphylococcus aureus Leads to Increased Virulence Through Human Immune Evasion.. MedComm, 6(8), e70313. Scopus1 WoS1 Europe PMC1 |
| 2025 | Le, H. -P., Hassan, K., Alsenaide, M., Purasinhala, K., Tran, A. T. T., Ramezanpour, M., . . . Losic, D. (2025). Electroconductive Antibacterial Bioinks Enable Electrical Stimulation Enhancement of Proliferation and Elongation of Human Skin Fibroblasts. ACS Biomaterials Science and Engineering, 11(9), 5661-5679. |
| 2025 | Rad, S. K., Li, R., Yeo, K. K. L., Cooksley, C., Shaghayegh, G., Vreugde, S., . . . Smith, E. (2025). Cell Line-Dependent Internalization, Persistence, and Immunomodulatory Effects of Staphylococcus aureus in Triple-Negative Breast Cancer. Cancers, 17(18), 2947-1-2947-25. Scopus2 WoS2 Europe PMC1 |
| 2024 | Connell, J. T., Yeo, K., Bouras, G., Bassiouni, A., Fenix, K., Cooksley, C., . . . Psaltis, A. J. (2024). Enhanced phylogenetic insights into the microbiome of chronic rhinosinusitis through the novel application of long read 16S rRNA gene amplicon sequencing.. Rhinology, 0(0), 0. Scopus4 WoS4 Europe PMC3 |
| 2024 | Yeo, K., Li, R., Wu, F., Bouras, G., Mai, L. T. H., Smith, E., . . . Fenix, K. (2024). Identification of consensus head and neck cancer-associated microbiota signatures: a systematic review and meta-analysis of 16S rRNA and The Cancer Microbiome Atlas datasets. Journal of Medical Microbiology, 73(2), 001799-1-001799-18. Scopus6 WoS5 Europe PMC7 |
| 2024 | Kennewell, T. L., Haidari, H., Mashtoub, S., Howarth, G. S., Bennett, C., Cooksley, C. M., . . . Kopecki, Z. (2024). Deferiprone-Gallium-Protoporphyrin Chitogel decreases Pseudomonas aeruginosa biofilm infection without impairing wound healing. Materials, 17(4), 1-19. Scopus3 WoS2 Europe PMC3 |
| 2024 | Murphy, W., Liu, S., Javadiyan, S., Vyskocil, E., Feizi, S., Callejas, C., . . . Psaltis, A. J. (2024). An In Vitro Study Evaluating the Safety of Mesalazine on Human Nasoepithelial Cells. International Journal of Molecular Sciences, 25(5), 2796. Scopus2 WoS2 Europe PMC1 |
| 2024 | Murphy, W., Liu, S., Hon, K., Finnie, J., Bouras, G. S., Feizi, S., . . . Psaltis, A. J. (2024). A Novel Model of Staphylococcus aureus-Induced Lymphoplasmacytic Rhinosinusitis in Rats. International Journal of Molecular Sciences, 25(6), 3336-1-3336-13. Scopus1 WoS1 Europe PMC1 |
| 2024 | Megow, A., Bouras, G., Ooi, E. H., Vreugde, S., Psaltis, A., & Wormald, P. J. (2024). Double blind randomized controlled trial measuring the efficacy of nebulized steroid at half dose in comparison to high volume squeeze bottle steroid irrigation in management of patients with chronic rhinosinusitis. International Forum of Allergy and Rhinology, 14(8), 1375-1377. Scopus3 WoS1 Europe PMC1 |
| 2024 | Kennewell, T. L., Haidari, H., Mashtoub, S., Howarth, G. S., Wormald, P. J., Cowin, A. J., . . . Kopecki, Z. (2024). Deferiprone and Gallium-Protoporphyrin Chitogel as an antimicrobial treatment: Preclinical studies demonstrating antimicrobial activity for S. aureus infected cutaneous wounds. International Journal of Biological Macromolecules, 276(Pt 1), 133874. Scopus5 WoS4 Europe PMC3 |
| 2024 | Connell, J. T., Bouras, G., Yeo, K., Fenix, K., Cooksley, C., Bassiouni, A., . . . Psaltis, A. J. (2024). Characterising the allergic fungal rhinosinusitis microenvironment using full-length 16S rRNA gene amplicon sequencing and fungal ITS sequencing.. Allergy, 79(11), 3082-3094. Scopus8 WoS6 Europe PMC4 |
| 2024 | Candy, N. G., Ramezanpour, M., Bouras, G., Chegeni, N., Chataway, T., Ormsby, R. J., . . . Psaltis, A. J. (2024). Differential proteomic expression in non-functional pituitary neuroendocrine tumours and pituitary glands. Rhinology, 62(6), 750-758. Scopus1 WoS1 Europe PMC2 |
| 2024 | Lee, J., Carda-Diéguez, M., Vreugde, S., Cooksley, C., Mashayamombe, M., Dawson, J., . . . Kidd, S. P. (2024). Characterising the role of enolase in a stable Small Colony Variant of Staphylococcus aureus isolated from a diabetic foot infection patient with osteomyelitis.. Microbial Pathogenesis, 196, 106918. Scopus1 |
| 2024 | Yeo, K., Wu, F., Li, R., Smith, E., Wormald, P. -J., Valentine, R., . . . Fenix, K. (2024). Is Short-Read 16S rRNA Sequencing of Oral Microbiome Sampling a Suitable Diagnostic Tool for Head and Neck Cancer?. Pathogens, 13(10), 826-1-826-20. Scopus3 WoS3 Europe PMC3 |
| 2024 | Meymivand, A., Shirani, M., Yamini, Y., Shahhosseini, S., Kashani, M. N., Pourmehran, O., & Vreugde, S. (2024). Polymeric membrane supports in electromembrane extraction: An overview of various options, methodologies, and modifications. TrAC - Trends in Analytical Chemistry, 181(Part B), 117994-1-117994-17. Scopus1 WoS1 |
| 2024 | Ramezanpour, M., Feizi, S., Arachchige, H. D. P., Bouras, G., Cooksley, C., Shaghayegh, G., . . . Vreugde, S. (2024). Evaluation of mucosal barrier disruption due to Staphylococcus lugdunensis and Staphylococcus epidermidis exoproteins in patients with chronic rhinosinusitis. International Forum of Allergy and Rhinology, 15(3), 267-277. Scopus1 WoS1 |
| 2024 | Feizi, S., Awad, M., Ramezanpour, M., Cooksley, C., Murphy, W., Prestidge, C. A., . . . Vreugde, S. (2024). Promoting the Efficacy of Deferiprone-Gallium-Protoporphyrin (IX) against <i>Mycobacterium abscessus</i> Intracellular Infection with Lipid Liquid Crystalline Nanoparticles.. ACS applied materials & interfaces, 16(51), 70274-70283. Scopus1 WoS1 Europe PMC1 |
| 2024 | Houtak, G., Nepal, R., Bouras, G., Shaghayegh, G., Bennett, C., Finnie, J., . . . Vreugde, S. (2024). Staphylococcus aureus Biofilm-Secreted Factors Cause Mucosal Damage, Mast Cell Infiltration, and Goblet Cell Hyperplasia in a Rat Rhinosinusitis Model. International Journal of Molecular Sciences, 25(6), 3402-1-3402-22. Scopus6 WoS5 Europe PMC6 |
| 2024 | Dhungana, G., Nepal, R., Houtak, G., Bouras, G., Vreugde, S., & Malla, R. (2024). Preclinical characterization and in silico safety assessment of three virulent bacteriophages targeting carbapenem-resistant uropathogenic Escherichia coli. International Microbiology, 27(6), 1747-1763. Scopus6 Europe PMC5 |
| 2024 | Megow, A., Bouras, G., Alsuliman, Y., Cooksley, C., Vyskocil, E., Murphy, W., . . . Wormald, P. -J. (2024). Chitogel with deferiprone following endoscopic sinus surgery: improved wound healing and microbiome. Frontiers in Surgery, 11, 1338209-1-1338209-13. Scopus1 |
| 2024 | Shaghayegh, G., Cooksley, C., Bouras, G., Panchatcharam, B. S., Feizi, S., Javadian, S., . . . Vreugde, S. (2024). S. aureus biofilm properties correlate with immune B cell subset frequencies and severity of chronic rhinosinusitis. Clinical Immunology, 263, 110221-1-110221-16. Scopus3 WoS3 Europe PMC2 |
| 2024 | Yeo, K., Connell, J., Bouras, G., Smith, E., Murphy, W., Hodge, J. -C., . . . Fenix, K. A. (2024). A comparison between full-length 16S rRNA Oxford nanopore sequencing and Illumina V3-V4 16S rRNA sequencing in head and neck cancer tissues. Arch Microbiol, 206(6), 248-1-248-14. Scopus15 WoS15 Europe PMC12 |
| 2024 | Le, H. -P., Hassan, K., Ramezanpour, M., Campbell, J. A., Tung, T. T., Vreugde, S., & Losic, D. (2024). Development of novel iron(III) crosslinked bioinks comprising carboxymethyl cellulose, xanthan gum, and hyaluronic acid for soft tissue engineering applications. Journal of Materials Chemistry B, 12(27), 6627-6642. Scopus10 WoS11 Europe PMC7 |
| 2024 | Tuli, J. F., Ramezanpour, M., Cooksley, C., Bouras, G. S., Ogi, K., Feizi, S., . . . Vreugde, S. (2024). Increased antibiotic resistance of Pseudomonas aeruginosa isolates from chronic rhinosinusitis patients grown in anaerobic conditions. Laryngoscope Investigative Otolaryngology, 9(3), e1244-1-e1244-9. Scopus2 WoS3 Europe PMC4 |
| 2024 | Bouras, G., Houtak, G., Wick, R. R., Mallawaarachchi, V., Roach, M. J., Papudeshi, B., . . . Vreugde, S. (2024). Hybracter: enabling scalable, automated, complete and accurate bacterial genome assemblies. Microbial Genomics, 10(5), 001244-1-001244-15. Scopus42 WoS43 Europe PMC46 |
| 2024 | Bouras, G., Judd, L. M., Edwards, R. A., Vreugde, S., Stinear, T. P., & Wick, R. R. (2024). How low can you go? Short-read polishing of Oxford Nanopore bacterial genome assemblies. Microbial Genomics, 10(6), 001254-1-001254-9. Scopus48 WoS49 Europe PMC55 |
| 2023 | Bouras, G., Nepal, R., Houtak, G., Psaltis, A. J., Wormald, P. -J., & Vreugde, S. (2023). Pharokka: a fast scalable bacteriophage annotation tool. Bioinformatics, 39(1), 1-4. Scopus278 WoS280 Europe PMC290 |
| 2023 | Shaghayegh, G., Cooksley, C., Bouras, G. S., Panchatcharam, B. S., Idrizi, R., Jana, M., . . . Vreugde, S. (2023). Chronic rhinosinusitis patients display an aberrant immune cell localization with enhanced S aureus biofilm metabolic activity and biomass. Journal of Allergy and Clinical Immunology, 151(3), 723-736.e16. Scopus10 WoS10 |
| 2023 | Farnoud, A., Tofighian, H., Baumann, I., Ahookhosh, K., Pourmehran, O., Cui, X., . . . Schmid, O. (2023). Numerical and Machine Learning Analysis of the Parameters Affecting the Regionally Delivered Nasal Dose of Nano- and Micro-Sized Aerosolized Drugs. Pharmaceuticals, 16(1), 81-1-81-14. Scopus11 WoS9 Europe PMC7 |
| 2023 | Feizi, S., Cooksley, C. M., Ramezanpour, M., Nepal, R., Psaltis, A. J., Wormald, P. -J., & Vreugde, S. (2023). Colloidal silver against macrophage infections and biofilms of atypical mycobacteria.. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 36(4), 913-925. Scopus11 WoS10 Europe PMC4 |
| 2023 | Dhakal, B., Li, C. M. Y., Ramezanpour, M., Houtak, G., Li, R., Bouras, G., . . . Fenix, K. (2023). Proteomic characterisation of perhexiline treatment on THP-1 M1 macrophage differentiation. Frontiers in Immunology, 14, 13 pages. Scopus3 WoS3 Europe PMC3 |
| 2023 | Shaghayegh, G., Cooksley, C., Bouras, G., Nepal, R., Houtak, G., Panchatcharam, B. S., . . . Vreugde, S. (2023). Staphylococcus aureus biofilm properties and chronic rhinosinusitis severity scores correlate positively with total CD4+ T-cell frequencies and inversely with its Th1, Th17 and regulatory cell frequencies. Immunology, 170(1), 120-133. Scopus13 WoS10 Europe PMC7 |
| 2023 | Lee, J., Mashayamombe, M., Walsh, T. P., Kuang, B. K. P., Pena, G. N., Vreugde, S., . . . Kidd, S. P. (2023). The bacteriology of diabetic foot ulcers and infections and incidence of Staphylococcus aureus Small Colony Variants.. Journal of medical microbiology, 72(6), 001716-1-001716-11. Scopus14 WoS12 Europe PMC11 |
| 2023 | Mascarenhas, A. R., Vediappan, R. S., Jukes, A. K., Bouras, G., Kaukas, L. M., Chryssidis, S., . . . Wormald, P. -J. (2023). Haemostatic efficacy and inflammatory response of a novel beta-chitin patch in a cerebral small vessel injury model - A pilot study. Journal of Clinical Neuroscience, 114, 70-76. |
| 2023 | Bouras, G., Sheppard, A. E., Mallawaarachchi, V., & Vreugde, S. (2023). Plassembler: an automated bacterial plasmid assembly tool.. Bioinformatics (Oxford, England), 39(7), btad409. Scopus33 WoS34 Europe PMC48 |
| 2023 | Cherian, L. M., Liu, S., Hon, K., Ramezanpour, M., Hu, H., Javadiyan, S., . . . Vreugde, S. (2023). Hydrocortisone metabolism by Staphylococcus: effects on anti-inflammatory and antimicrobial action.. International forum of allergy & rhinology, 14(3), 711-715. Scopus1 Europe PMC1 |
| 2023 | Pourmehran, O., Zarei, K., Pourchez, J., Vreugde, S., Psaltis, A., & Wormald, P. -J. (2023). Advancements in Acoustic Drug Delivery for Paranasal Sinuses: A Comprehensive Review. International Journal of Pharmaceutics, 644, 123277-1-123277-18. Scopus9 WoS9 Europe PMC5 |
| 2023 | Feizi, S., Awad, M., Nepal, R., Cooksley, C. M., Psaltis, A. J., Wormald, P. -J., & Vreugde, S. (2023). Deferiprone-gallium-protoporphyrin (IX): A promising treatment modality against Mycobacterium abscessus.. Tuberculosis (Edinburgh, Scotland), 142, 102390. Scopus3 WoS3 Europe PMC1 |
| 2023 | Shaghayegh, G., Cooksley, C., Bouras, G., Houtak, G., Nepal, R., Psaltis, A. J., . . . Vreugde, S. (2023). S. aureus biofilm metabolic activity correlates positively with patients’ eosinophil frequencies and disease severity in chronic rhinosinusitis. Microbes and Infection, 25(8), 105213-1-105213-10. Scopus11 WoS7 Europe PMC5 |
| 2023 | Huang, S., Hon, K., Bennett, C., Hu, H., Menberu, M., Wormald, P. J., . . . Liu, S. (2023). Corrigendum: Corynebacterium accolens inhibits Staphylococcus aureus induced mucosal barrier disruption(Front. Microbiol., (2022), 13, (984741), 10.3389/fmicb.2022.984741). Frontiers in Microbiology, 14, 1279422. |
| 2023 | Houtak, G., Bouras, G., Nepal, R., Shaghayegh, G., Cooksley, C., Psaltis, A. J., . . . Vreugde, S. (2023). The intra-host evolutionary landscape and pathoadaptation of persistent Staphylococcus aureus in chronic rhinosinusitis. Microbial Genomics, 9(11), 001128-1-001128-21. Scopus6 WoS6 Europe PMC8 |
| 2022 | Mahnaz, R., Harrison, B., Hon, K., Gohar, S., Hadi, R., Aaron, F. K., . . . Sarah, V. (2022). Characterization of human nasal organoids from chronic rhinosinusitis patients.. Biology open, 11(8), 1-8. Scopus3 WoS3 Europe PMC3 |
| 2022 | Sabab, A., Vediappan, R. S., Finnie, J., McAdam, C. J., Jukes, A., Vreugde, S., & Wormald, P. J. (2022). Efficacy and Safety of Novel Beta-Chitin Patches as Haemostat in Rat Vascular and Neurosurgical Model. Frontiers in Surgery, 9, 830364-1-830364-9. Scopus2 WoS2 |
| 2022 | Nepal, R., Houtak, G., Karki, S., Dhungana, G., Vreugde, S., & Malla, R. (2022). Genomic characterization of three bacteriophages targeting multidrug resistant clinical isolates of Escherichia, Klebsiella and Salmonella. Archives of Microbiology, 204(6), 1-9. Scopus6 WoS7 Europe PMC7 |
| 2022 | Liu, S., Hon, K., Bouras, G. S., Psaltis, A. J., Shearwin, K., Wormald, P. -J., & Vreugde, S. (2022). APTC-C-SA01: A Novel Bacteriophage Cocktail Targeting Staphylococcus aureus and MRSA Biofilms. International Journal of Molecular Sciences, 23(11), 6116-1-6116-18. Scopus23 WoS22 Europe PMC16 |
| 2022 | Shaghayegh, G., Cooksley, C., Ramezanpour, M., Wormald, P. -J., Psaltis, A. J., & Vreugde, S. (2022). Chronic Rhinosinusitis, S. aureus Biofilm and Secreted Products, Inflammatory Responses, and Disease Severity. Biomedicines, 10(6), 1-28. Scopus33 WoS27 Europe PMC21 |
| 2022 | Goggin, R. K., Bennett, C. A., Cooksley, C. M., Bassiouni, A., Bialasiewicz, S., Wormald, P. J., . . . Psaltis, A. J. (2022). Viral presence and the bacterial microbiome in chronic rhinosinusitis. Australian Journal of Otolaryngology, 5, 1-8. Scopus1 WoS1 |
| 2022 | Huang, S., Hon, K., Bennett, C., Hu, H., Menberu, M., Wormald, P. -J., . . . Liu, S. (2022). Corynebacterium accolens inhibits Staphylococcus aureus induced mucosal barrier disruption. Frontiers in Microbiology, 13, 1-11. Scopus21 WoS16 Europe PMC21 |
| 2022 | Lee, J., Carda-Diéguez, M., Žiemytė, M., Vreugde, S., Cooksley, C., Crosby, H. A., . . . Kidd, S. P. (2022). Functional mgrA Influences Genetic Changes within a Staphylococcus aureus Cell Population over Time. Journal of Bacteriology, 204(10), e00138-22-1-e00138-22-19. Scopus9 WoS6 Europe PMC6 |
| 2022 | Hon, K., Liu, S., Cooksley, C., Vreugde, S., & Psaltis, A. J. (2022). Low pH nasal rinse solution enhances mupirocin antimicrobial efficacy. Rhinology, 60(3), 218-228. Scopus4 Europe PMC1 |
| 2022 | Vediappan, R. S., Bennett, C., Cooksley, C., Bassiouni, A., Scott, J. R., Al Suliman, Y. A., . . . Wormald, P. -J. (2022). Wound healing in endoscopic sinus surgery - Phase 1 clinical trial evaluating the role of Chitogel with adjuvants.. Clin Otolaryngol, 48(2), 158-166. Scopus8 WoS7 Europe PMC5 |
| 2022 | Javadiyan, S., Cooksley, C. M., Bouras, G. S., Kao, S. S. T., Bennett, C. A., Wormald, P. J., . . . Psaltis, A. J. (2022). Investigation of Kappa Carrageenan's muco-adhesive, antibacterial, and anti-biofilm properties. International Forum of Allergy and Rhinology, 12(3), 302-305. Scopus6 WoS7 Europe PMC4 |
| 2022 | Menberu, M. A., Cooksley, C., Ramezanpour, M., Bouras, G., Wormald, P. -J., Psaltis, A. J., & Vreugde, S. (2022). In vitro and in vivo evaluation of probiotic properties of Corynebacterium accolens isolated from the human nasal cavity. Microbiological Research, 255, 10 pages. Scopus16 WoS15 Europe PMC13 |
| 2022 | Feizi, S., Cooksley, C. M., Nepal, R., Psaltis, A. J., Wormald, P. -J., & Vreugde, S. (2022). Silver nanoparticles as a bioadjuvant of antibiotics against biofilm-mediated infections with methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa in chronic rhinosinusitis patients. Pathology, 54(4), 453-459. Scopus34 WoS32 Europe PMC19 |
| 2022 | Shrestha, K., Van Strien, J., Shang, Y., Fletcher, D. F., Petersen, P., Vreugde, S., . . . Inthavong, K. (2022). Effect of breathing profiles on nebuliser drug delivery targeting the paranasal sinuses in a post-operative nasal cavity. Journal of Aerosol Science, 161, 1-19. Scopus15 WoS14 |
| 2022 | Hon, K., Liu, S., Camens, S., Bouras, G. S., Psaltis, A. J., Wormald, P. -J., & Vreugde, S. (2022). APTC-EC-2A: A Lytic Phage Targeting Multidrug Resistant E. coli Planktonic Cells and Biofilms. Microorganisms, 10(1), 1-18. Scopus14 WoS12 Europe PMC11 |
| 2022 | Nepal, R., Houtak, G., Wormald, P. -J., Psaltis, A. J., & Vreugde, S. (2022). Prophage: a crucial catalyst in infectious disease modulation. The Lancet Microbe, 3(3), e162-e163. Scopus14 WoS11 Europe PMC14 |
| 2022 | Hon, K., Liu, S., Cooksley, C., Vreugde, S., & Psaltis, A. J. (2022). Low pH nasal rinse solution enhances mupirocin antimicrobial efficacy.. Rhinology, 60(3), 218-228. WoS3 Europe PMC1 |
| 2022 | Megow, A., Alsuliman, Y., Bouras, G., Menberu, M., Vyskocil, E., Vreugde, S., & Wormald, P. -J. (2022). Chitogel following endoscopic sinus surgery promotes a healthy microbiome and reduces post-operative infections.. International forum of allergy & rhinology, 12(11), 1362-1376. Scopus9 WoS10 Europe PMC8 |
| 2022 | Javadiyan, S., Germein, K. C., Cooksley, C. M., Ramezanpour, M., Singh, N., Wormald, P. -J., . . . Psaltis, A. J. (2022). In Vitro safety and anti-bacterial efficacy assessment of Acriflavine.. Allergy, 77(6), 1917-1920. Scopus4 WoS3 Europe PMC2 |
| 2022 | Hu, H., Liu, S., Hon, K., Psaltis, A. J., Wormald, P. J., & Vreugde, S. (2022). Staphylococcal protein A modulates inflammation by inducing interferon signaling in human nasal epithelial cells. Inflammation Research, 72(2), 1-12. Scopus6 WoS6 Europe PMC9 |
| 2021 | Suzuki, M., Cooksley, C., Suzuki, T., Ramezanpour, M., Nakazono, A., Nakamaru, Y., . . . Vreugde, S. (2021). TLR Signals in Epithelial Cells in the Nasal Cavity and Paranasal Sinuses. Frontiers in Allergy, 2, 780425-1-780425-11. Scopus15 WoS13 Europe PMC13 |
| 2021 | Vahaji, S., Shang, Y., Zhang, Y., Wong, E., Rezk, A., Yeo, L., . . . Inthavong, K. (2021). Optimising Aerosol Delivery for Maxillary Sinus Deposition in a Post-FESS Sinonasal Cavities. AEROSOL AND AIR QUALITY RESEARCH, 21(12), 16 pages. Scopus9 WoS9 |
| 2021 | Nepal, R., Houtak, G., Shaghayegh, G., Bouras, G., Shearwin, K., Psaltis, A. J., . . . Vreugde, S. (2021). Prophages encoding human immune evasion cluster genes are enriched in Staphylococcus aureus isolated from chronic rhinosinusitis patients with nasal polyps. Microbial Genomics, 7(12), 000726-1-000726-19. Scopus27 WoS23 Europe PMC18 |
| 2021 | Ogi, K., Liu, S., Ramezanpour, M., Cooksley, C., Javadiyan, S., Fujieda, S., . . . Psaltis, A. J. (2021). Trimellitic anhydride facilitates transepithelial permeability disrupting tight junctions in sinonasal epithelial cells. Toxicology Letters, 353, 27-33. Scopus4 WoS4 Europe PMC4 |
| 2021 | Feizi, S., Javadiyan, S., Cooksley, C. M., Shaghayegh, G., Psaltis, A. J., Wormald, P., & Vreugde, S. (2021). Green synthesized colloidal silver is devoid of toxic effects on primary human nasal epithelial cells in vitro. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 157, 112606-1-112606-10. Scopus9 WoS7 Europe PMC3 |
| 2021 | Sabab, A., Vreugde, S., Jukes, A., & Wormald, P. J. (2021). The potential of chitosan-based haemostats for use in neurosurgical setting – Literature review. Journal of Clinical Neuroscience, 94, 128-134. Scopus11 WoS7 Europe PMC4 |
| 2021 | Ramezanpour, M., Bolt, H., Hon, K., Bouras, G. S., Psaltis, A. J., Wormald, P. J., & Vreugde, S. (2021). Cytokine-induced modulation of sars-cov2 receptor expression in primary human nasal epithelial cells. Pathogens, 10(7), 18 pages. Scopus3 WoS3 Europe PMC2 |
| 2021 | Ramezanpour, M., Ogi, K., Liu, S., Tuli, J. F., Bennett, C., Masanobu, S., . . . Vreugde, S. (2021). Der p 1 disrupts the epithelial barrier and induces IL-6 production in patients with house dust mite allergic rhinitis. Frontiers in Allergy, 2, 692049-1-692049-9. Scopus17 WoS15 Europe PMC13 |
| 2021 | Rastin, H., Mansouri, N., Tung, T. T., Hassan, K., Mazinani, A., Ramezanpour, M., . . . Losic, D. (2021). Converging 2D nanomaterials and 3D bioprinting technology: state-of-the-art, challenges, and potential outlook in biomedical applications. Advanced Healthcare Materials, 10(22), e2101439-1-e2101439-50. Scopus29 WoS28 Europe PMC10 |
| 2021 | Sabab, A., Liu, S., Javadiyan, S., McAdam, C. J., Hanton, L. R., Jukes, A., . . . Wormald, P. -J. (2021). The effect of chemical and structural modifiers on the haemostatic process and cytotoxicity of the beta-chitin patch. Scientific Reports, 11(1), 1-15. Scopus4 WoS4 Europe PMC3 |
| 2021 | Camens, S., Hon, K., Liu, S., Bouras, G. S., Psaltis, A. J., Wormald, P., & Vreugde, S. (2021). Preclinical Development of a Bacteriophage Cocktail for Treating Multidrug Resistant Pseudomonas aeruginosa Infections. Microorganisms, 9(9), 2001-1-2001-16. Scopus17 WoS15 Europe PMC16 |
| 2021 | Menberu, M. A., Hayes, A. J., Liu, S., Psaltis, A. J., Wormald, P. -J., & Vreugde, S. (2021). Tween 80 and its derivative oleic acid promote the growth of Corynebacterium accolens and inhibit Staphylococcus aureus clinical isolates. Int Forum Allergy Rhinol, 11(4), 810-813. Scopus9 WoS9 Europe PMC8 |
| 2021 | Vediappan, R. S., Bennett, C., Cooksley, C., Finnie, J., Trochsler, M., Quarrington, R. D., . . . Wormald, P. J. (2021). Prevention of adhesions post-abdominal surgery: Assessing the safety and efficacy of Chitogel with Deferiprone in a rat model. PLoS One, 16(1), e0244503-1-e0244503-17. Scopus7 WoS6 Europe PMC5 |
| 2021 | Suzuki, M., Ramezanpour, M., Cooksley, C., Ogi, K., Psaltis, A. J., Nakamaru, Y., . . . Vreugde, S. (2021). Metallothionein-3 is a clinical biomarker for tissue zinc levels in nasal mucosa. Auris Nasus Larynx, 48(5), 890-897. Scopus4 WoS4 Europe PMC4 |
| 2021 | Menberu, M. A., Liu, S., Cooksley, C., Hayes, A. J., Psaltis, A. J., Wormald, P. -J., & Vreugde, S. (2021). Corynebacterium accolens Has Antimicrobial Activity against Staphylococcus aureus and Methicillin-Resistant S. aureus Pathogens Isolated from the Sinonasal Niche of Chronic Rhinosinusitis Patients. Pathogens, 10(2), 1-19. Scopus51 WoS48 Europe PMC45 |
| 2021 | Feizi, S., Cooksley, C. M., Bouras, G. S., Prestidge, C. A., Coenye, T., Psaltis, A. J., . . . Vreugde, S. (2021). Colloidal silver combating pathogenic Pseudomonas aeruginosa and MRSA in chronic rhinosinusitis.. Colloids and surfaces. B, Biointerfaces, 202, 1-10. Scopus20 WoS21 Europe PMC14 |
| 2021 | Rastin, H., Ramezanpour, M., Hassan, K., Mazinani, A., Tung, T. T., Vreugde, S., & Losic, D. (2021). 3D bioprinting of a cell-laden antibacterial polysaccharide hydrogel composite. Carbohydrate Polymers, 264, 117989-1-117989-12. Scopus76 WoS62 Europe PMC37 |
| 2021 | Liu, S., Zhao, Y., Hayes, A., Hon, K., Zhang, G., Bennett, C., . . . Vreugde, S. (2021). Overcoming bacteriophage insensitivity in Staphylococcus aureus using clindamycin and azithromycinat sub-inhibitory concentrations. Allergy, 76(11), 3446-3458. Scopus18 WoS15 Europe PMC14 |
| 2021 | Nakazono, A., Nakamaru, Y., Ramezanpour, M., Kondo, T., Watanabe, M., Hatakeyama, S., . . . Homma, A. (2021). Fluticasone Propionate Suppresses Poly(I:C)-Induced ACE2 in Primary Human Nasal Epithelial Cells. Frontiers in Cellular and Infection Microbiology, 11, 1-10. Scopus14 WoS12 Europe PMC11 |
| 2021 | Tuli, J. F., Ramezanpour, M., Cooksley, C., Psaltis, A. J., Wormald, P. -J., & Vreugde, S. (2021). Association between mucosal barrier disruption by Pseudomonas aeruginosa exoproteins and asthma in patients with chronic rhinosinusitis.. Allergy, 76(11), 3459-3469. Scopus30 WoS27 Europe PMC24 |
| 2021 | Cherian, L. M., Bassiouni, A., Cooksley, C. M., Vreugde, S., Wormald, P., & Psaltis, A. J. (2021). The clinical outcomes of medical therapies in chronic rhinosinusitis is independent of microbiomic outcomes: a double-blinded, randomised placebo-controlled trial.. Rhinology, 58(3), 386-390. Scopus15 WoS16 Europe PMC10 |
| 2021 | Kao, S., Bassiouni, A., Ramezanpour, M., Finnie, J., Chegeni, N., Colella, A. D., . . . Psaltis, A. J. (2021). Proteomic analysis of nasal mucus samples of healthy and chronic rhinosinusitis patients. Journal of Allergy and Clinical Immunology, 147(1), 168-178. Scopus42 WoS32 Europe PMC34 |
| 2021 | Connell, J., Bassiouni, A., Wormald, P., Vreugde, S., & Psaltis, A. (2021). Optimal primer selection for sinus microbiome profiling: A comparative analysis of the V1‐V3 and V3‐4 16S target regions. International Forum of Allergy & Rhinology, 11(12), 1698-1702. Scopus5 WoS5 Europe PMC4 |
| 2021 | Mazinani, A., Rastin, H., Nine, M. J., Lee, J., Tikhomirova, A., Tung, T. T., . . . Losic, D. (2021). Comparative antibacterial activity of 2D materials coated on the porous-titania. Journal of Materials Chemistry B, 32(32), 6412-6424. Scopus21 WoS19 Europe PMC9 |
| 2021 | Pourmehran, O., Arjomandi, M., Cazzolato, B., Tian, Z., Vreugde, S., Javadiyan, S., . . . Wormald, P. -J. (2021). Acoustic drug delivery to the maxillary sinus. International Journal of Pharmaceutics, 606, 120927-1-120927-15. Scopus23 WoS20 Europe PMC9 |
| 2020 | Ooi, M. L., Drilling, A. J., James, C., Moratti, S., Vreugde, S., Psaltis, A. J., & Wormald, P. J. (2020). Efficacy of anti-biofilm gel, chitogel-mupirocin-budesonide in a sheep sinusitis model. Australian Journal of Otolaryngology(Hong Kong), 3(May), 8 pages. Scopus1 |
| 2020 | Ramezanpour, M., Hu, H., Lau, A., Liu, S., De Silva, A., Bolt, H., . . . Vreugde, S. (2020). Increased serum IgG4 associates with asthma and tissue eosinophilia in chronic rhinosinusitis patients. Pathogens, 9(10), 1-6. Scopus4 WoS4 Europe PMC3 |
| 2020 | Suzuki, M., Suzuki, T., Watanabe, M., Hatakeyama, S., Kimura, S., Nakazono, A., . . . Homma, A. (2020). Role of intracellular zinc in molecular and cellular function in allergic inflammatory diseases. Allergology International, 70(2), 190-200. Scopus33 Europe PMC28 |
| 2020 | Paramasivan, S., Psaltis, A. J., Wormald, P. J., & Vreugde, S. (2020). Tertiary Lymphoid Organs: A Primer for Otolaryngologists.. Laryngoscope, 131(8), 1697-1703. Scopus2 WoS2 Europe PMC2 |
| 2020 | Suzuki, M., Ramezanpour, M., Cooksley, C., Lee, T. J., Jeong, B., Kao, S., . . . Vreugde, S. (2020). Zinc-depletion associates with tissue eosinophilia and collagen depletion in chronic rhinosinusitis. Rhinology, 58(5), 451-459. Scopus17 WoS15 Europe PMC15 |
| 2020 | Kao, S. S. T., Ramezanpour, M., Bassiouni, A., Finnie, J., Wormald, P. J., Vreugde, S., & Psaltis, A. J. (2020). Barrier disruptive effects of mucus isolated from chronic rhinosinusitis patients. Allergy, 75(1), 200-203. Scopus12 WoS13 Europe PMC9 |
| 2020 | Curragh, D. S., Bassiouni, A., Macias-Valle, L., Vreugde, S., Wormald, P. -J., Selva, D., & Psaltis, A. J. (2020). The Microbiome of the Nasolacrimal System and Its Role in Nasolacrimal Duct Obstruction. Ophthalmic plastic and reconstructive surgery, 36(1), 80-85. Scopus14 WoS12 Europe PMC9 |
| 2020 | Dong, D., Thomas, N., Ramezanpour, M., Alkis, P., Huang, S., Zhao, Y., . . . Vreudge, S. (2020). Inhibition of Staphylococcus aureus and Pseudomonas aeruginosa biofilms by quatsomes in low concentrations. Experimental Biology and Medicine, 245(1), 34-41. Scopus17 WoS18 Europe PMC12 |
| 2020 | Vediappan, R. S., Mascarenhas, A., Nguyen-Hoang, A., Fong, S. A., Jukes, A., Richter, K., . . . Wormald, P. (2020). Prevention of peridural adhesions in spinal surgery: assessing safety and efficacy of Chitogel with Deferiprone in a sheep model. Journal of Clinical Neuroscience, 72, 378-385. Scopus13 WoS12 Europe PMC9 |
| 2020 | Bassiouni, A., Ou, J., Schreiber, A., Geoghegan, J., Tsykin, A., Psaltis, A. J., . . . Vreugde, S. (2020). The global transcriptomic signature in sinonasal tissues reveals roles for tissue type and chronic rhinosinusitis disease phenotype. Rhinology, 58(3), 273-283. Scopus12 WoS10 Europe PMC9 |
| 2020 | Paramasivan, S., Bassiouni, A., Shiffer, A., Dillon, M. R., Cope, E. K., Cooksley, C., . . . Psaltis, A. J. (2020). The international sinonasal microbiome study (ISMS): a multi-centre, multi-national characterization of sinonasal bacterial ecology. Allergy, 75(8), 2033-2045. Scopus72 WoS68 Europe PMC62 |
| 2020 | Gouzos, M., Ramezanpour, M., Bassiouni, A., Psaltis, A. J., Wormald, P. J., & Vreugde, S. (2020). Antibiotics affect ROS production and fibroblast migration in an in-vitro model of sinonasal wound healing. Frontiers in Cellular and Infection Microbiology, 10, 110-1-110-12. Scopus23 WoS19 Europe PMC16 |
| 2020 | Bassiouni, A., Paramasivan, S., Shiffer, A., Dillon, M. R., Cope, E. K., Cooksley, C., . . . Psaltis, A. J. (2020). Microbiotyping the Sinonasal Microbiome.. Frontiers in Cellular and Infection Microbiology, 10, 137. Scopus33 WoS27 Europe PMC27 |
| 2020 | Vediappan, R. S., Bennett, C., Bassiouni, A., Smith, M., Finnie, J., Trochsler, M., . . . Wormald, P. J. (2020). A novel rat model to test intra-abdominal anti-adhesive therapy. Frontiers in Surgery, 7, 12. Scopus11 WoS8 Europe PMC6 |
| 2020 | Goggin, R., Bennett, C., Ramezanpour, M., Hu, H., Fenix, K., Bassiouni, A., . . . Vreugde, S. (2020). Association between viral infection and increased mucosal eosinophils and CD8<sup>+</sup>CD103<sup>+</sup> T cells in chronic rhinosinusitis. International Forum of Allergy and Rhinology, 10(8), 978-980. Scopus1 |
| 2020 | Ramezanpour, M., Smith, J. P., Pstaltis, A. J., Wormald, P. J., & Vreugde, S. (2020). In vitro safety evaluation of a povidone‐iodine solution applied to human nasal epithelial cells. International Forum of Allergy and Rhinology, 10(10), 1141-1148. Scopus33 WoS30 Europe PMC25 |
| 2020 | Ramezanpour, M., Kao, S., Bassiouni, A., Chegeni, N., Colella, A., Chataway, K., . . . Psaltis, A. (2020). Scoping review of chronic rhinosinusitis proteomicsc rhinosinusitis proteomics. Rhinology, 58(5), 418-470. |
| 2020 | Panchatcharam, B. S., Cooksley, C. M., Ramezanpour, M., Vediappan, R. S., Bassiouni, A., Wormald, P. J., . . . Vreugde, S. (2020). Staphylococcus aureus biofilm exoproteins are cytotoxic to human nasal epithelial barrier in Chronic Rhinosinusitis. International Forum of Allergy and Rhinology, 10(7), 871-883. Scopus29 WoS22 Europe PMC18 |
| 2020 | Kao, S. S. -T., Bassiouni, A., Ramezanpour, M., Chegeni, N., Colella, A. D., Chataway, T. K., . . . Psaltis, A. J. (2020). Scoping review of chronic rhinosinusitis proteomics.. Rhinology, 58(5), 418-470. Scopus18 WoS15 Europe PMC12 |
| 2019 | Ooi, M. L., Drilling, A. J., Morales, S., Fong, S., Moraitis, S., MacIas-Valle, L., . . . Wormald, P. J. (2019). Safety and tolerability of bacteriophage therapy for chronic rhinosinusitis due to staphylococcus aureus. JAMA Otolaryngology-Head and Neck Surgery, 145(8), 723-729. Scopus143 WoS131 Europe PMC119 |
| 2019 | Govindaraju, R., Cherian, L., Macias-Valle, L., Murphy, J., Gouzos, M., Vreugde, S., . . . Psaltis, A. J. (2019). Extent of maxillary sinus surgery and its effect on instrument access, irrigation penetration, and disease clearance. International Forum of Allergy and Rhinology, 9(10), 1097-1104. Scopus17 WoS15 Europe PMC15 |
| 2019 | Kao, S. S. T., Ramezanpour, M., Bassiouni, A., Wormald, P. J., Psaltis, A. J., & Vreugde, S. (2019). The effect of neutrophil serine proteases on human nasal epithelial cell barrier function. International Forum of Allergy and Rhinology, 9(10), 7 pages. Scopus34 WoS32 Europe PMC27 |
| 2019 | Ooi, M. L., Jothin, A., Bennett, C., Ooi, E. H., Vreugde, S., Psaltis, A. J., & Wormald, P. J. (2019). Manuka honey sinus irrigations in recalcitrant chronic rhinosinusitis: phase 1 randomized, single-blinded, placebo-controlled trial. International Forum of Allergy and Rhinology, 9(12), 1470-1477. Scopus28 WoS25 Europe PMC21 |
| 2019 | Hu, H., Ramezanpour, M., Hayes, A. J., Liu, S., Psaltis, A. J., Wormald, P., & Vreugde, S. (2019). Sub-Inhibitory Clindamycin and Azithromycin reduce S. aureus Exoprotein Induced Toxicity, Inflammation, Barrier Disruption and Invasion.. Journal of clinical medicine, 8(10), 16 pages. Scopus19 WoS18 Europe PMC15 |
| 2019 | Murphy, J., Ramezanpour, M., Drilling, A., Roscioli, E., Psaltis, A. J., Wormald, P. J., & Vreugde, S. (2019). In vitro characteristics of an airway barrier-disrupting factor secreted by Staphylococcus aureus. International Forum of Allergy and Rhinology, 9(2), 187-196. Scopus14 WoS13 Europe PMC11 |
| 2019 | Fong, S. A., Drilling, A. J., Ooi, M. L., Paramasivan, S., Finnie, J. W., Morales, S., . . . Wormald, P. J. (2019). Safety and efficacy of a bacteriophage cocktail in an in vivo model of Pseudomonas aeruginosa sinusitis. Translational Research, 206, 41-56. Scopus40 WoS39 Europe PMC34 |
| 2019 | Ramezanpour, M., Bolt, H., Psaltis, A., Wormald, P. J., & Vreugde, S. (2019). Inducing a Mucosal Barrier–Sparing Inflammatory Response in Laboratory-Grown Primary Human Nasal Epithelial Cells. Current Protocols in Toxicology, 80(1), e69. Scopus17 Europe PMC13 |
| 2019 | Cherian, L. M., Cooksley, C., Richter, K., Ramezanpour, M., Paramasivan, S., Wormald, P. J., . . . Psaltis, A. J. (2019). Effect of commercial nasal steroid preparation on bacterial growth. International Forum of Allergy and Rhinology, 9(7), 766-775. Scopus11 WoS11 Europe PMC7 |
| 2019 | Ramezanpour, M., Smith, J. L. P., Ooi, M. L., Gouzos, M., Psaltis, A. J., Wormald, P. J., & Vreugde, S. (2019). Deferiprone has anti-inflammatory properties and reduces fibroblast migration in vitro. Scientific Reports, 9(1), 9 pages. Scopus25 WoS23 Europe PMC21 |
| 2019 | Li, J., Ramezanpour, M., Fong, S. A., Cooksley, C., Murphy, J., Suzuki, M., . . . Vreugde, S. (2019). Pseudomonas aeruginosa exoprotein-induced barrier disruption correlates with elastase activity and marks Chronic Rhinosinusitis severity. Frontiers in Cellular and Infection Microbiology, 9, 9 pages. Scopus34 WoS29 Europe PMC27 |
| 2019 | Goggin, R. K., Bennett, C. A., Bialasiewicz, S., Vediappan, R. S., Vreugde, S., Wormald, P. J., & Psaltis, A. J. (2019). The presence of virus significantly associates with chronic rhinosinusitis disease severity. Allergy European Journal of Allergy and Clinical Immunology, 74(8), 1569-1572. Scopus18 WoS14 Europe PMC13 |
| 2019 | Bennett, C., Ramezanpour, M., Cooksley, C., Vreugde, S., & Psaltis, A. J. (2019). Kappa-carrageenan sinus rinses reduce inflammation and intracellular Staphylococcus aureus infection in airway epithelial cells. International Forum of Allergy and Rhinology, 9(8), 918-925. Scopus12 WoS11 Europe PMC7 |
| 2018 | Ooi, M., Richter, K., Bennett, C., Macias-Valle, L., Vreugde, S., Psaltis, A., & Wormald, P. (2018). Topical colloidal silver for the treatment of recalcitrant chronic rhinosinusitis. Frontiers in Microbiology, 9(article no. 720), 1-7. Scopus22 WoS20 Europe PMC16 |
| 2018 | Ooi, M., Richter, K., Drilling, A., Thomas, N., Prestidge, C. A., James, C., . . . Wormald, P. J. (2018). Safety and efficacy of topical chitogel- deferiprone- gallium protoporphyrin in a sheep sinusitis model. Frontiers in Microbiology, 9(917), 1-9. Scopus17 WoS16 Europe PMC12 |
| 2018 | Suzuki, M., Ramezanpour, M., Cooksley, C., Li, J., Nakamaru, Y., Homma, A., . . . Vreugde, S. (2018). Sirtuin-1 Controls Poly (I:C)-Dependent Matrix Metalloproteinase 9 Activation in Primary Human Nasal Epithelial Cells. American journal of respiratory cell and molecular biology, 59(4), 500-510. Scopus16 WoS16 Europe PMC14 |
| 2018 | Murphy, J., Ramezanpour, M., Roscioli, E., Psaltis, A. J., Wormald, P. J., & Vreugde, S. (2018). Mucosal zinc deficiency in chronic rhinosinusitis with nasal polyposis contributes to barrier disruption and decreases ZO-1. Allergy European Journal of Allergy and Clinical Immunology, 73(10), 2095-2097. Scopus27 WoS26 Europe PMC22 |
| 2018 | Ramezanpour, M., Bolt, H., Psaltis, A., Wormald, P., & Vreugde, S. (2018). Primary human nasal epithelial cells: a source of poly (I:C) LMW-induced IL-6 production. Scientific Reports, 8(1), 8 pages. Scopus26 WoS24 Europe PMC25 |
| 2018 | Zhang, G., Zhao, Y., Hayes, A. J., Psaltis, A. J., Wormald, P. J., & Vreugde, S. (2018). Staphylococcus aureus small colony variants: Prevalence in chronic rhinosinusitis and induction by antibiotics. Allergy European Journal of Allergy and Clinical Immunology, 73(12), 2403-2405. Scopus6 WoS6 Europe PMC6 |
| 2018 | Paramasivan, S., Lester, S., Lau, A., Ou, J., Psaltis, A., Wormald, P., & Vreugde, S. (2018). Tertiary lymphoid organs: A novel target in patients with chronic rhinosinusitis. Journal of Allergy and Clinical Immunology, 142(5), 1673-1676. Scopus12 WoS12 Europe PMC7 |
| 2018 | Goggin, R., Bennett, C., Bassiouni, A., Bialasiewicz, S., Vreugde, S., Wormald, P., & Psaltis, A. (2018). Comparative viral sampling in the sinonasal passages; Different viruses at different sites. Frontiers in Cellular and Infection Microbiology, 8(SEP), 8 pages. Scopus11 WoS9 Europe PMC8 |
| 2018 | Bardy, J., Sarovich, D., Price, E., Steinig, E., Tong, S., Drilling, A., . . . Psaltis, A. (2018). Staphylococcus aureus from patients with chronic rhinosinusitis show minimal genetic association between polyp and non-polyp phenotypes 06 Biological Sciences 0604 Genetics. BMC Ear, Nose and Throat Disorders, 18(1), 8 pages. Scopus10 WoS8 Europe PMC8 |
| 2018 | Zhao, Y., Bassiouni, A., Tanjararak, K., Vreugde, S., Wormald, P., & Psaltis, A. (2018). Role of fungi in chronic rhinosinusitis through ITS sequencing. Laryngoscope, 128(1), 16-22. Scopus41 WoS32 Europe PMC29 |
| 2018 | Murphy, J., Ramezanpour, M., Stach, N., Dubin, G., Psaltis, A., Wormald, P., & Vreugde, S. (2018). Staphylococcus Aureus V8 protease disrupts the integrity of the airway epithelial barrier and impairs IL-6 production in vitro. Laryngoscope, 128(1), 8-15. Scopus47 WoS39 Europe PMC37 |
| 2018 | Zhang, G., Zhao, Y., Paramasivan, S., Richter, K., Morales, S., Wormald, P., & Vreugde, S. (2018). Bacteriophage effectively kills multidrug resistant Staphylococcus aureus clinical isolates from chronic rhinosinusitis patients. International Forum of Allergy and Rhinology, 8(3), 406-414. Scopus42 WoS37 Europe PMC31 |
| 2018 | Miljkovic, D., Psaltis, A., Wormald, P., & Vreugde, S. (2018). Naive and effector B-cell subtypes are increased in chronic rhinosinusitis with polyps. American Journal of Rhinology and Allergy, 32(1), 3-6. Scopus16 WoS15 Europe PMC10 |
| 2017 | Miljkovic, D., Psaltis, A., Wormald, P., & Vreugde, S. (2017). Chronic rhinosinusitis with polyps is characterized by increased mucosal and blood Th17 effector cytokine producing cells. Frontiers in Physiology, 8(DEC), 7 pages. Scopus13 WoS11 Europe PMC13 |
| 2017 | Fong, S., Drilling, A., Morales, S., Cornet, M., Woodworth, B., Fokkens, W., . . . Wormald, P. (2017). Activity of bacteriophages in removing biofilms of pseudomonas aeruginosa isolates from chronic rhinosinusitis patients. Frontiers in Cellular and Infection Microbiology, 7(SEP), 1-11. Scopus138 WoS127 Europe PMC113 |
| 2017 | Ramezanpour, M., Murphy, J., Smith, J., Vreugde, S., & Psaltis, A. (2017). In vitro safety evaluation of human nasal epithelial cell monolayers exposed to carrageenan sinus wash. International Forum of Allergy and Rhinology, 7(12), 1170-1177. Scopus24 WoS20 Europe PMC15 |
| 2017 | Oue, S., Ramezanpour, M., Paramasivan, S., Miljkovic, D., Cooksley, C. M., Bassiouni, A., . . . Vreugde, S. (2017). Increased IL-13 expression is independently associated with neo-osteogenesis in patients with chronic rhinosinusitis. Journal of Allergy and Clinical Immunology, 140(5), 1444-1448.e11. Scopus12 WoS12 Europe PMC8 |
| 2017 | Richter, K., Facal, P., Thomas, N., Vandecandelaere, I., Ramezanpour, M., Cooksley, C., . . . Vreugde, S. (2017). Taking the silver bullet colloidal silver particles for the topical treatment of biofilm-related infections. ACS Applied Materials and Interfaces, 9(26), 21631-21638. Scopus49 WoS45 Europe PMC32 |
| 2017 | Richter, K., Thomas, N., Zhang, G., Prestidge, C., Coenye, T., Wormald, P. -J., & Vreugde, S. (2017). Deferiprone and gallium-protoporphyrin have the capacity to potentiate the activity of antibiotics in Staphylococcus aureus small colony variants. Frontiers in Cellular and Infection Microbiology, 7(JUN), 280-1-280-10. Scopus57 WoS48 Europe PMC37 |
| 2017 | Ou, J., Bassiouni, A., Drilling, A., Psaltis, A., Vreugde, S., & Wormald, P. (2017). The persistence of intracellular Staphylococcus aureus in the sinuses: a longitudinal study.. Rhinology, 55(4), 305-311. Scopus20 WoS17 Europe PMC15 |
| 2017 | Ramezanpour, M., Rayan, A., Smith, J., & Vreugde, S. (2017). The effect of topical treatments for CRS on the sinonasal epithelial barrier. Rhinology, 55(2), 161-169. Scopus14 WoS13 Europe PMC11 |
| 2017 | Chan, C., Richter, K., Wormald, P., Psaltis, A., & Vreugde, S. (2017). Alloiococcus otitidis forms multispecies biofilm with Haemophilus influenzae: effects on antibiotic susceptibility and Growth in Adverse Conditions. Frontiers in Cellular and Infection Microbiology, 7(AUG), 344-1-344-9. Scopus25 WoS18 Europe PMC16 |
| 2017 | Jukes, A., Murphy, J., Vreugde, S., Psaltis, A., & Wormald, P. (2017). Nano-hemostats and a Pilot Study of Their Use in a Large Animal Model of Major Vessel Hemorrhage in Endoscopic Skull Base Surgery. Journal of Neurological Surgery, Part B: Skull Base, 78(3), 215-221. Scopus2 WoS2 Europe PMC1 |
| 2017 | Lau, A., Lester, S., Moraitis, S., Ou, J., Psaltis, A., McColl, S., . . . Vreugde, S. (2017). Tertiary lymphoid organs in recalcitrant chronic rhinosinusitis. Journal of Allergy and Clinical Immunology, 139(4), 1371-1373. Scopus25 WoS23 Europe PMC18 |
| 2017 | Miljkovic, D., Ou, J., Kirana, C., Hulse, K., Hauben, E., Psaltis, A., . . . Vreugde, S. (2017). Discordant frequencies of tissue-resident and circulating CD180-negative B cells in chronic rhinosinusitis. International Forum of Allergy and Rhinology, 7(6), 609-614. Scopus5 WoS5 Europe PMC3 |
| 2017 | Drilling, A., Ooi, M., Miljkovic, D., James, C., Speck, P., Vreugde, S., . . . Wormald, P. (2017). Long-term safety of topical bacteriophage application to the frontal sinus region. Frontiers in Cellular and Infection Microbiology, 7(FEB), 1-8. Scopus42 WoS40 Europe PMC38 |
| 2017 | Chan, C., Wabnitz, D., Bassiouni, A., Wormald, P., Vreugde, S., & Psaltis, A. (2017). Identification of the bacterial reservoirs for the middle ear using phylogenic analysis. JAMA Otolaryngology - Head and Neck Surgery, 143(2), 155-161. Scopus31 WoS28 Europe PMC25 |
| 2017 | Richter, K., Thomas, N., Claeys, J., McGuane, J., Prestidge, C., Coenye, T., . . . Vreugde, S. (2017). A topical hydrogel with deferiprone and gallium-protoporphyrin targets bacterial iron metabolism and has antibiofilm activity. Antimicrobial Agents and Chemotherapy, 61(6), e00481-17-1-e00481-17-11. Scopus71 WoS68 Europe PMC51 |
| 2016 | Chan, C., Wabnitz, D., Bardy, J., Bassiouni, A., Wormald, P., Vreugde, S., & Psaltis, A. (2016). The microbiome of otitis media with effusion. Laryngoscope, 126(12), 2844-2851. Scopus59 WoS54 Europe PMC46 |
| 2016 | Vreugde, S., & Wormald, P. (2016). Innate lymphoid type 2 cells in chronic rhinosinusitis. Current Opinion in Allergy and Clinical Immunology, 16(1), 7-12. Scopus6 WoS5 Europe PMC4 |
| 2016 | Bassiouni, A., Ou, J., Rajiv, S., Cantero, D., Vreugde, S., & Wormald, P. (2016). Subepithelial inflammatory load and basement membrane thickening in refractory chronic rhinosinusitis with nasal polyposis: A histopathological study. International Forum of Allergy and Rhinology, 6(3), 248-255. Scopus37 WoS34 Europe PMC33 |
| 2016 | Drilling, A., Cooksley, C., Chan, C., Wormald, P., & Vreugde, S. (2016). Fighting sinus-derived Staphylococcus aureus biofilms in vitro with a bacteriophage-derived muralytic enzyme. International Forum of Allergy and Rhinology, 6(4), 349-355. Scopus26 WoS28 Europe PMC23 |
| 2016 | Cleland, E., Bassiouni, A., Vreugde, S., & Wormald, P. (2016). The bacterial microbiome in chronic rhinosinusitis: Richness, diversity, postoperative changes, and patient outcomes. American Journal of Rhinology and Allergy, 30(1), 37-43. Scopus66 WoS61 Europe PMC51 |
| 2016 | Richter, K., Ramezanpour, M., Thomas, N., Prestidge, C. A., Wormald, P. J., & Vreugde, S. (2016). Mind “De GaPP”: in vitro efficacy of deferiprone and gallium-protoporphyrin against Staphylococcus aureus biofilms. International Forum of Allergy and Rhinology, 6(7), 737-743. Scopus45 WoS41 Europe PMC37 |
| 2016 | Ramezanpour, M., Moraitis, S., Smith, J., Wormald, P., & Vreugde, S. (2016). Th17 cytokines disrupt the airway mucosal barrier in chronic rhinosinusitis. Mediators of Inflammation, 2016, 9798206-1-9798206-7. Scopus72 WoS68 Europe PMC57 |
| 2016 | Miljkovic, D., Psaltis, A., Wormald, P., & Vreugde, S. (2016). T regulatory and Th17 cells in chronic rhinosinusitis with polyps. International Forum of Allergy and Rhinology, 6(8), 826-834. Scopus27 WoS23 Europe PMC20 |
| 2016 | Ou, J., Drilling, A., Singhal, D., Tan, N., Wallis-Hill, D., Vreugde, S., . . . Wormald, P. (2016). Association of intracellular Staphylococcus aureus with prognosis in chronic rhinosinusitis. International Forum of Allergy and Rhinology, 6(8), 792-799. Scopus32 WoS28 Europe PMC26 |
| 2016 | Ou, J., Drilling, A., Cooksley, C., Bassiouni, A., Kidd, S., Psaltis, A., . . . Vreugde, S. (2016). Reduced innate immune response to a Staphylococcus aureus small colony variant compared to its wild-type parent strain. Frontiers in Cellular and Infection Microbiology, 6(DEC), 187-1-187-9. Scopus23 WoS23 Europe PMC22 |
| 2016 | Hasan, S., Thomas, N., Thierry, B., Vreugde, S., Wormald, P., & Prestidge, C. (2016). Recent trends on the use of nanoparticles for nitric oxide delivery in antimicrobial applications. Drug Delivery Letters, 6(1), 3-10. Scopus2 |
| 2015 | Cantero, D., Cooksley, C., Bassiouni, A., Tran, H., Roscioli, E., Wormald, P., & Vreugde, S. (2015). Staphylococcus aureus biofilms induce apoptosis and expression of interferon-γ, interleukin-10, and interleukin-17A on human sinonasal explants. American Journal of Rhinology and Allergy, 29(1), 23-28. Scopus21 WoS18 Europe PMC12 |
| 2015 | Rajiv, S., Drilling, A., Bassiouni, A., James, C., Vreugde, S., & Wormald, P. (2015). Topical colloidal silver as an anti-biofilm agent in a Staphylococcus aureus chronic rhinosinusitis sheep model. International Forum of Allergy and Rhinology, 5(4), 283-288. Scopus24 WoS21 Europe PMC17 |
| 2015 | Malik, Z., Roscioli, E., Murphy, J., Ou, J., Bassiouni, A., Wormald, P., & Vreugde, S. (2015). Staphylococcus aureus impairs the airway epithelial barrier in vitro. International Forum of Allergy and Rhinology, 5(6), 551-556. Scopus62 WoS56 Europe PMC48 |
| 2015 | Bassiouni, A., Cleland, E., Psaltis, A., Vreugde, S., & Wormald, P. (2015). Sinonasal microbiome sampling: a comparison of techniques. PLoS One, 10(4), e0123216-1-e0123216-13. Scopus48 WoS50 Europe PMC46 |
| 2015 | Rajiv, S., Rodgers, S., Bassiouni, A., Vreugde, S., & Wormald, P. (2015). Role of crushed skeletal muscle extract in hemostasis. International Forum of Allergy & Rhinology, 5(5), 431-434. Scopus5 WoS4 Europe PMC4 |
| 2015 | Jardeleza, C., Thierry, B., Rao, S., Rajiv, S., Drilling, A., Miljkovic, D., . . . Wormald, P. (2015). An in vivo safety and efficacy demonstration of a topical liposomal nitric oxide donor treatment for Staphylococcus aureus biofilm-associated rhinosinusitis. Translational Research, 166(6), 683-692. Scopus33 WoS31 Europe PMC26 |
| 2015 | Dong, D., Thomas, N., Thierry, B., Vreugde, S., Prestidge, C., & Wormald, P. (2015). Distribution and Inhibition of liposomes on Staphylococcus aureus and Pseudomonas aeruginosa biofilm. PLoS One, 10(6), e0131806. Scopus81 WoS76 Europe PMC47 |
| 2015 | Thomas, N., Dong, D., Richter, K., Ramezanpour, M., Vreugde, S., Thierry, B., . . . Prestidge, C. (2015). Quatsomes for the treatment of Staphylococcus aureus biofilm. Journal of Materials Chemistry B, 3(14), 2770-2777. Scopus30 WoS28 Europe PMC17 |
| 2015 | Cooksley, C., Roscioli, E., Wormald, P., & Vreugde, S. (2015). TLR response pathways in NuLi-1 cells and primary human nasal epithelial cells. Molecular Immunology, 68(2 part B), 476-483. Scopus20 WoS19 Europe PMC16 |
| 2014 | Tan, N., Cooksley, C., Roscioli, E., Drilling, A., Douglas, R., Wormald, P., & Vreugde, S. (2014). Small-colony variants and phenotype switching of intracellular Staphylococcus aureus in chronic rhinosinusitis. Allergy, 69(10), 1364-1371. Scopus38 WoS38 Europe PMC35 |
| 2014 | Miljkovic, D., Bassiouni, A., Cooksley, C., Ou, J., Hauben, E., Wormald, P., & Vreugde, S. (2014). Association between group 2 innate lymphoid cells enrichment, nasal polyps and allergy in chronic rhinosinusitis. Allergy, 69(9), 1154-1161. Scopus154 WoS140 Europe PMC130 |
| 2014 | Padhye, V., Valentine, R., Paramasivan, S., Jardeleza, C., Bassiouni, A., Vreugde, S., & Wormald, P. (2014). Early and late complications of endoscopic hemostatic techniques following different carotid artery injury characteristics. International Forum of Allergy and Rhinology, 4(8), 651-657. Scopus35 WoS32 Europe PMC30 |
| 2014 | Cleland, E., Drilling, A., Bassiouni, A., James, C., Vreugde, S., & Wormald, P. (2014). Probiotic manipulation of the chronic rhinosinusitis microbiome. International Forum of Allergy and Rhinology, 4(4), 309-314. Scopus47 WoS43 Europe PMC41 |
| 2014 | Cleland, E., Bassioni, A., Boase, S., Dowd, S., Vreugde, S., & Wormald, P. (2014). The fungal microbiome in chronic rhinosinusitis: richness, diversity, postoperative changes and patient outcomes. International Forum of Allergy and Rhinology, 4(4), 259-265. Scopus69 WoS62 Europe PMC58 |
| 2014 | Drilling, A., Morales, S., Jardeleza, C., Vreugde, S., Speck, P., & Wormald, P. (2014). Bacteriophage reduces biofilm of Staphylococcus aureus ex vivo isolates from chronic rhinosinusitis patients. American Journal of Rhinology and Allergy, 28(1), 3-11. Scopus60 WoS54 Europe PMC49 |
| 2014 | Drilling, A., Coombs, G., Tan, H., Pearson, J., Boase, S., Psaltis, A., . . . Wormald, P. (2014). Cousins, siblings, or copies: the genomics of recurrent Staphylococcus aureus infections in chronic rhinosinusitis. International Forum of Allergy and Rhinology, 4(12), 953-960. Scopus25 WoS22 Europe PMC22 |
| 2014 | Jardeleza, C., Rao, S., Thierry, B., Gajjar, P., Vreugde, S., Prestidge, C., & Wormald, P. (2014). Liposome-encapsulated ISMN: a novel nitric oxide-based therapeutic agent against Staphylococcus aureus biofilms. PLoS One, 9(3), 1-9. Scopus44 WoS39 Europe PMC25 |
| 2014 | Drilling, A., Morales, S., Boase, S., Jervis-Bardy, J., James, C., Jardeleza, C., . . . Wormald, P. (2014). Safety and efficacy of topical bacteriophage and ethylenediaminetetraacetic acid treatment of Staphylococcus aureus infection in a sheep model of sinusitis. International Forum of Allergy & Rhinology, 4(3), 176-186. Scopus56 WoS53 Europe PMC46 |
| 2014 | Paramasivan, S., Drilling, A., Jardeleza, C., Jervis-Bardy, J., Vreugde, S., & Wormald, P. (2014). Methylglyoxal-augmented manuka honey as a topical anti-Staphylococcus aureus biofilm agent: safety and efficacy in an in vivo model. International Forum of Allergy & Rhinology, 4(3), 187-195. Scopus61 WoS51 Europe PMC42 |
| 2014 | Goggin, R., Jardeleza, C., Wormald, P., & Vreugde, S. (2014). Colloidal silver: a novel treatment for Staphylococcus aureus biofilms?. International Forum of Allergy & Rhinology, 4(3), 171-175. Scopus31 WoS29 Europe PMC22 |
| 2014 | Goggin, R., Jardeleza, C., Wormald, P., & Vreugde, S. (2014). Corticosteroids directly reduce Staphylococcus aureus biofilm growth: an in vitro study. The Laryngoscope, 124(3), 602-607. Scopus28 WoS23 Europe PMC22 |
| 2014 | Tan, N., Cooksley, C., Paramasivan, S., Vreugde, S., & Wormald, P. (2014). Safety evaluation of a sinus surfactant in an explant-based cytotoxicity assay. The Laryngoscope, 124(2), 369-372. Scopus8 WoS6 Europe PMC5 |
| 2013 | Jardeleza, C., Miljkovic, D., Baker, L., Boase, S., Tan, N., Koblar, S., . . . Vreugde, S. (2013). Inflammasome gene expression alterations in Staphylococcus aureus biofilm-associated chronic rhinosinusitis. Rhinology, 51(4), 315-322. Scopus14 WoS12 Europe PMC11 |
| 2013 | Cantero Cajas, D., Cooksley, C., Bassiouni, A., Wormald, P., & Vreugde, S. (2013). Staphylococcus aureus biofilm activates the nucleotide-binding oligomerization domain containing 2 (Nod2) pathway and proinflammatory factors on a human sinonasal explant model. International Forum of Allergy & Rhinology, 3(11), 877-884. Scopus13 WoS11 Europe PMC10 |
| 2013 | Cantero Cajas, D., Cooksley, C., Jardeleza, C., Bassiouni, A., Jones, D., Wormald, P., & Vreugde, S. (2013). A human nasal explant model to study Staphylococcus aureus biofilm in vitro. International Forum of Allergy & Rhinology, 3(7), 556-562. Scopus15 WoS16 Europe PMC17 |
| 2013 | Tan, N., Foreman, A., Jardeleza, C., Douglas, R., Vreugde, S., & Wormald, P. (2013). Intracellular Staphylococcus aureus: the Trojan horse of recalcitrant chronic rhinosinusitis?. International Forum of Allergy & Rhinology, 3(4), 261-266. Scopus61 WoS54 Europe PMC49 |
| 2013 | Jardeleza, C., Jones, D., Baker, L., Miljkovic, D., Boase, S., Tan, N., . . . Wormald, P. (2013). Gene expression differences in nitric oxide and reactive oxygen species regulation point to an altered innate immune response in chronic rhinosinusitis. International Forum of Allergy & Rhinology, 3(3), 193-198. Scopus16 WoS15 Europe PMC14 |
| 2013 | Jardeleza, C., Miljkovic, D., Baker, L., Boase, S., Tan, N. C. W., Koblar, S. A., . . . Vreugde, S. (2013). Inflammasome gene expression alterations in Staphylococcus aureus biofilm-associated chronic rhinosinusitis. Rhinology journal, 51(4), 315-322. |
| 2012 | Tan, N. W., Tran, H., Foreman, A., Jardeleza, C., Vreugde, S., & Wormald, P. J. (2012). Identifying intracellular Staphylococcus aureus in chronic rhinosinusitis: A direct comparison of techniques. American Journal of Rhinology & Allergy, 26(6), 444-449. Scopus17 WoS16 Europe PMC12 |
| 2012 | Tan, N. W., Tran, H., Roscioli, E., Wormald, P. J., & Vreugde, S. (2012). Prevention of false positive binding during immunofluorescence of Staphylococcus aureus infected tissue biopsies. Journal of Immunological Methods, 384(1-2), 111-117. Scopus8 WoS8 Europe PMC7 |
| 2006 | Vreugde, S., Ferrai, C., Miluzio, A., Hauben, E., Marchisio, P., Crippa, M., . . . Biffo, S. (2006). Nuclear myosin VI enhances RNA polymerase II-dependent transcription. Molecular Cell, 23(5), 749-755. Scopus118 WoS107 Europe PMC102 |
| 2006 | Friedmann, E., Hauben, E., Maylandt, K., Schleeger, S., Vreugde, S., Lichtenthaler, S., . . . Martoglio, B. (2006). SPPL2a and SPPL2b promote intramembrane proteolysis of TNFalpha in activated dendritic cells to trigger IL-12 production. Nature Cell Biology, 8(8), 849-854. |
| 2006 | Friedmann, E., Hauben, E., Maylandt, K., Schleeger, S., Vreugde, S., Lichtenthaler, S. F., . . . Martoglio, B. (2006). SPPL2a and SPPL2b promote intramembrane proteolysis of TNFα in activated dendritic cells to trigger IL-12 production. Nature Cell Biology, 8(8), 843-848. Scopus178 WoS173 Europe PMC155 |
| 2002 | Vreugde, S., Erven, A., Kros, C. J., Marcotti, W., Fuchs, H., Kurima, K., . . . Steel, K. P. (2002). Beethoven, a mouse model for dominant, progressive hearing loss DFNA36. Nature Genetics, 30(3), 257-258. Scopus239 WoS224 Europe PMC211 |
| 2002 | Walsh, T., Walsh, V., Vreugde, S., Hertzano, R., Shahin, H., Haika, S., . . . Avraham, K. B. (2002). From flies' eyes to our ears: Mutations in a human class III myosin cause progressive nonsyndromic hearing loss DFNB30. Proceedings of the National Academy of Sciences of the United States of America, 99(11), 7518-7523. Scopus201 WoS181 Europe PMC167 |
| 2002 | Adato, A., Vreugde, S., Joensuu, T., Avidan, N., Hamalainen, R., Belenkiy, O., . . . Lancet, D. (2002). USH3A transcripts encode clarin-1, a four-transmembrane-domain protein with a possible role in sensory synapses. European Journal of Human Genetics, 10(6), 339-350. Scopus155 WoS140 Europe PMC128 |
| 2000 | Frydman, M., Vreugde, S., Nageris, B. I., Weiss, S., Vahava, O., & Avraham, K. B. (2000). Clinical characterization of genetic hearing loss caused by a mutation in the POU4F3 transcription factor. Archives of Otolaryngology Head and Neck Surgery, 126(5), 633-637. Scopus26 WoS22 Europe PMC20 |
| 2000 | Sobe, T., Vreugde, S., Shahin, H., Berlin, M., Davis, N., Kanaan, M., . . . Avraham, K. (2000). The prevalence and expression of inherited connexin 26 mutations associated with nonsyndromic hearing loss in the Israeli population. Human Genetics, 106(1), 50-57. Scopus143 WoS125 Europe PMC103 |
| 1999 | Sobe, T., Erlich, P., Berry, A., Korostichevsky, M., Vreugde, S., Avraham, K. B., . . . Shohat, M. (1999). High frequency of the deafness-associated 167delT mutation in the connexin 26 (GJB2) gene in Israeli Ashkenazim [2]. American Journal of Medical Genetics, 86(5), 499-500. Scopus59 WoS55 Europe PMC41 |
| 1999 | Vreugde, S., Duttmann, R., Halama, A., & Deron, P. (1999). Metastasis of a renal cell carcinoma to the nose and paranasal sinuses. Acta Oto Rhino Laryngologica Belgica, 53(2), 129-131. Scopus9 Europe PMC7 |
| 1997 | De Maeseneer, M., Vreugde, S., Laureys, S., Sartoris, D. J., De Ridder, F., & Osteaux, M. (1997). Calcific tendinitis of the longus colli muscle. Head and Neck, 19(6), 545-548. Scopus51 WoS38 Europe PMC28 |
| 1994 | Vreugde, S. (1994). Nutritional aspects of dysphagia.. Acta Oto Rhino Laryngologica Belgica, 48(2), 229-234. Scopus7 |
| Year | Citation |
|---|---|
| 2023 | Vreugde, S., & Wormald, P. J. (2023). The Current Concepts of Biofilms and Superantigens. In A. Swift, S. Carrie, & C. de Souza (Eds.), Contemporary Rhinology: Science and Practice (pp. 91-100). Springer International Publishing. DOI |
| Year | Citation |
|---|---|
| 2016 | Lau, A. H. Y., Lester, S., Moraitis, S., Ou, J., Rischmueller, M., Wormald, P. J., & Vreugde, S. (2016). Tertiary Lymphoid Organ in Chronic Rhinosinusitis. Poster session presented at the meeting of 2016 ASMR South Australian Scientific Meeting. Convention Centre, Adelaide, South Australia, Australia. |
| Year | Citation |
|---|---|
| 2025 | Bouras, G., Grigson, S., Mirdita, M., Heinzinger, M., Papudeshi, B., Mallawaarachchi, V., . . . Edwards, R. (2025). Protein Structure Informed Bacteriophage Genome Annotation with Phold. DOI Europe PMC2 |
| 2025 | Awad, M., Bouras, G., Feizi, S., Grigson, S., Wormald, P. -J., Psaltis, A., & Vreugde, S. (2025). LicD-Mediated Cell Wall Decoration Governs Phage Sensitivity in Enterococcus faecalis Clinical Isolates. DOI |
| 2024 | Bouras, G., Judd, L., Edwards, R., Vreugde, S., Stinear, T., & Wick, R. (2024). How low can you go? Short-read polishing of Oxford Nanopore bacterial genome assemblies. DOI Europe PMC3 |
| 2023 | Bouras, G., Houtak, G., Wick, R., Mallawaarachchi, V., Roach, M., Papudeshi, B., . . . Vreugde, S. (2023). Hybracter: Enabling Scalable, Automated, Complete and Accurate Bacterial Genome Assemblies. DOI |
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2025 | Principal Supervisor | Exploring the Potential of Engineered Phages for Mycobacterium Abscessus Treatment: Innovating Precision Therapy Against Resistant Infections | Doctor of Philosophy | Doctorate | Full Time | Mr Muhammad Imran |
| 2025 | Co-Supervisor | Engineering a Biocompatible Metal-Organic Framework (MOF) For Nasal Drug Delivery: Insights from Computational Fluid Dynamics (CFD) Models | Doctor of Philosophy | Doctorate | Full Time | Mr Nikzad Abbariki |
| 2025 | Co-Supervisor | Core-Silica Coated Mesoporous Nanoparticles for Enhanced Drug Delivery in Chronic Rhinosinusitis Treatment | Doctor of Philosophy | Doctorate | Full Time | Mrs Sara Aghili |
| 2025 | Co-Supervisor | Core-Silica Coated Mesoporous Nanoparticles for Enhanced Drug Delivery in Chronic Rhinosinusitis Treatment | Doctor of Philosophy | Doctorate | Full Time | Mrs Sara Aghili |
| 2025 | Principal Supervisor | Exploring the Potential of Engineered Phages for Mycobacterium Abscessus Treatment: Innovating Precision Therapy Against Resistant Infections | Doctor of Philosophy | Doctorate | Full Time | Mr Muhammad Imran |
| 2025 | Co-Supervisor | Engineering a Biocompatible Metal-Organic Framework (MOF) For Nasal Drug Delivery: Insights from Computational Fluid Dynamics (CFD) Models | Doctor of Philosophy | Doctorate | Full Time | Mr Nikzad Abbariki |
| 2024 | Principal Supervisor | Developing smart phage cocktails for difficult-to-treat infections | Doctor of Philosophy | Doctorate | Full Time | Mr Connor Jessop |
| 2024 | Principal Supervisor | Unravelling the underlying mechanisms of chronic rhinosinusitis (CRS) pathogenesis and exploring the potential of bacteriophages as a therapeutic option | Doctor of Philosophy | Doctorate | Full Time | Mr Md Hasib Adnan |
| 2024 | Co-Supervisor | A comprehensive Study of magnetic drug targeting in human maxillary sinuses for drug delivery applications | Doctor of Philosophy | Doctorate | Full Time | Mr Kavan Zarei |
| 2024 | Co-Supervisor | A comprehensive numerical and experimental study of transport phenomena in nebulizer drug delivery targeting paranasal sinuses | Doctor of Philosophy | Doctorate | Full Time | Mr Alireza Meymivand |
| 2024 | Co-Supervisor | Precision medicine in bacterial infections; exploring the use of personalised phage therapy and multi-omics technologies to improve the management of chronic rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Miss Isabella Amy Burdon |
| 2024 | Co-Supervisor | Bacteriophage therapy in CRS patient nasal wound healing | Doctor of Philosophy | Doctorate | Full Time | Mr Jordan Hall |
| 2024 | Principal Supervisor | Maximising the antimicrobial and anti-inflammatory performance of next generation therapeutics for Chronic Rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Mrs Marzieh Eskandarzadeh |
| 2024 | Co-Supervisor | A comprehensive Study of magnetic drug targeting in human maxillary sinuses for drug delivery applications | Doctor of Philosophy | Doctorate | Full Time | Mr Kavan Zarei |
| 2024 | Principal Supervisor | Unravelling the underlying mechanisms of chronic rhinosinusitis (CRS) pathogenesis and exploring the potential of bacteriophages as a therapeutic option | Doctor of Philosophy | Doctorate | Full Time | Mr Md Hasib Adnan |
| 2024 | Co-Supervisor | Precision medicine in bacterial infections; exploring the use of personalised phage therapy and multi-omics technologies to improve the management of chronic rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Miss Isabella Amy Burdon |
| 2024 | Principal Supervisor | Developing smart phage cocktails for difficult-to-treat infections | Doctor of Philosophy | Doctorate | Full Time | Mr Connor Jessop |
| 2024 | Co-Supervisor | A comprehensive numerical and experimental study of transport phenomena in nebulizer drug delivery targeting paranasal sinuses | Doctor of Philosophy | Doctorate | Full Time | Mr Alireza Meymivand |
| 2024 | Principal Supervisor | Maximising the antimicrobial and anti-inflammatory performance of next generation therapeutics for Chronic Rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Mrs Marzieh Eskandarzadeh |
| 2024 | Co-Supervisor | Bacteriophage therapy in CRS patient nasal wound healing | Doctor of Philosophy | Doctorate | Full Time | Mr Jordan Hall |
| 2023 | Co-Supervisor | Target the tumour microbiome to improve head & neck cancer treatment outcomes | Doctor of Philosophy | Doctorate | Full Time | Mrs Lee Mai |
| 2023 | Principal Supervisor | Exploring The Efficacy Of Bacteriophage Therapy In Disrupting Poly-Microbial Biofilms In Chronic Rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Mr Xiaohan Sun |
| 2023 | Principal Supervisor | Potential use of essential oils from ethno-medicinal plants in clinical research | Doctor of Philosophy | Doctorate | Full Time | Miss Sumeena Karki |
| 2023 | Principal Supervisor | Investigating Phage, Microbe and Host Interactions by Integrating Systems Multiomics | Doctor of Philosophy | Doctorate | Full Time | Mr George Spyro Bouras |
| 2023 | Principal Supervisor | Studying the Potential of Bacteriophage Loaded Chitosan-Silk Hydrogel as a Novel Formulation for Chronically Infected Wounds | Doctor of Philosophy | Doctorate | Full Time | Ms Zahra Aliakbar Ahovan |
| 2023 | Principal Supervisor | Investigating Phage, Microbe and Host Interactions by Integrating Systems Multiomics | Doctor of Philosophy | Doctorate | Full Time | Mr George Spyro Bouras |
| 2023 | Co-Supervisor | Target the tumour microbiome to improve head & neck cancer treatment outcomes | Doctor of Philosophy | Doctorate | Full Time | Mrs Lee Mai |
| 2023 | Principal Supervisor | Potential use of essential oils from ethno-medicinal plants in clinical research | Doctor of Philosophy | Doctorate | Full Time | Miss Sumeena Karki |
| 2023 | Principal Supervisor | Exploring The Efficacy Of Bacteriophage Therapy In Disrupting Poly-Microbial Biofilms In Chronic Rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Mr Xiaohan Sun |
| 2023 | Principal Supervisor | Studying the Potential of Bacteriophage Loaded Chitosan-Silk Hydrogel as a Novel Formulation for Chronically Infected Wounds | Doctor of Philosophy | Doctorate | Full Time | Ms Zahra Aliakbar Ahovan |
| 2022 | Principal Supervisor | The role of various Staphylococcus species in eliciting inflammation in Chronic rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Mr Sintayehu Ambachew Wondemagegn |
| 2022 | Principal Supervisor | The role of various Staphylococcus species in eliciting inflammation in Chronic rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Mr Sintayehu Ambachew Wondemagegn |
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2023 - 2024 | Co-Supervisor | The Microbiome of Allergic Fungal Rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Dr James Thomas Connell |
| 2023 - 2024 | Co-Supervisor | Repurposing Mesalazine as a Potential Treatment Option for Chronic Rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Mr William Mark Murphy |
| 2021 - 2024 | Principal Supervisor | Characterising the Microbiome and its Diagnostic and Prognostic Value in Head and Neck Cancer | Doctor of Philosophy | Doctorate | Full Time | Mr Kenny Ker Li Yeo |
| 2021 - 2025 | Co-Supervisor | Development of An Animal Model of Endoscopic Small-Vessel Haemorrhage Control, Brain Manipulation and Dural Closure | Doctor of Philosophy | Doctorate | Full Time | Dr Annika Reann Mascarenhas |
| 2021 - 2023 | Co-Supervisor | Investigating Transcription Factors in the Human Airway Mucosal Immunoepigenetics of Chronic Inflammatory Disease | Master of Philosophy (Surgery) | Master | Full Time | Mr Harrison Burchill Bolt |
| 2020 - 2022 | Co-Supervisor | The Relationship Between S. Aureus Biofilm Properties, Inflammation, and Disease Severity in Chronic Rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Mrs Gohar Shaghayegh |
| 2020 - 2023 | Co-Supervisor | Topical Therapies for The Management of Recalcitrant Chronic Rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Dr Anna Katharina Megow |
| 2019 - 2023 | Principal Supervisor | The Adaption and Inflammation-Inducing Capacity of Staphylococcus Aureus in Chronic Rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Mr Ghais Houtak |
| 2019 - 2023 | Principal Supervisor | Role of Prophages in Staphylococcus aureus Virulence and Pathogenicity | Doctor of Philosophy | Doctorate | Full Time | Mr Roshan Nepal |
| 2018 - 2020 | Principal Supervisor | The Host-Microbe Interface in Chronic Rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Mr Sathish Paramasivan |
| 2018 - 2021 | Co-Supervisor | Modifying Post-Surgical Wound Healing | Doctor of Philosophy | Doctorate | Full Time | Rajan Vediappan |
| 2018 - 2020 | Principal Supervisor | The role of viruses in chronic rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Dr Rachel Katherine Goggin |
| 2018 - 2022 | Principal Supervisor | The Role of Colloidal Silver Synthesized from Corymbia Maculata in Eradicating Infection in Chronic Rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Miss Sholeh Feizi |
| 2018 - 2022 | Principal Supervisor | Investigating Microbiome - Targeted Treatments for Chronic Rhinosinusitis: A novel approach to combat dysbiosis in the nasal microbiome | Doctor of Philosophy | Doctorate | Full Time | Mrs Martha Menberu |
| 2017 - 2020 | Co-Supervisor | Staphylococcus aureus Exoproteins on Nasal Epithelial Barrier in Chronic Rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Dr Beula Subashini Panchatcharam |
| 2017 - 2020 | Co-Supervisor | Bacteriophage Therapy for Chronic Rhinosinusitis: Targeting Pseudomonas Aeruginosa Biofilms | Doctor of Philosophy | Doctorate | Full Time | Miss Stephanie Anne Fong |
| 2017 - 2020 | Co-Supervisor | Novel Topical Anti-biofilm Agents in the Treatment of Recalcitrant Chronic Rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Miss Mian Li Ooi |
| 2016 - 2019 | Co-Supervisor | Corticosteroids and the Sinonasal Microbiome | Doctor of Philosophy | Doctorate | Full Time | Dr Lisa Mary Cherian |
| 2016 - 2017 | Co-Supervisor | The microbiome of otitis media with effusion and the influence of Alloicoccus otitidis on Haemophilus influenzae in polymicrobial biofilm | Doctor of Philosophy | Doctorate | Full Time | Dr Chun Chan |
| 2015 - 2018 | Principal Supervisor | An Immunological Perspective of the Mucosal Inflammation in Chronic Rhinosinusitis – Lymphoid Neo-organogenesis and Humoral Immunity | Doctor of Philosophy | Doctorate | Full Time | Mr Aden Lau |
| 2015 - 2018 | Co-Supervisor | The Mucosal Barrier in Chronic Rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Mr Jae Viktor Murphy |
| 2014 - 2017 | Co-Supervisor | The Role of Immune Cells in Chronic Rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Ms Dijana Miljkovic |
| 2014 - 2017 | Principal Supervisor | Towards Novel Antibiofilm Strategies | Doctor of Philosophy | Doctorate | Full Time | APrf Katharina Richter |
| 2013 - 2015 | Co-Supervisor | Management of Major Vessel Haemorrhage in Endonasal Surgery | Doctor of Philosophy | Doctorate | Full Time | Vikram Padhye |
| 2012 - 2014 | Co-Supervisor | Nitric Oxide and Staphylococcus aureus Biofilms: Defining their Intricate Relationship in Chronic Rhinosinusitis | Doctor of Philosophy | Doctorate | Part Time | Dr Camille Jardeleza |
| 2012 - 2014 | Co-Supervisor | The innate immune response to Staphylococcus aureus biofilms on human sinonasal explants | Doctor of Philosophy | Doctorate | Full Time | Mr Daniel Anibal Cantero Cajas |
| 2012 - 2013 | Co-Supervisor | Intracellular Staphylococcus aureus in chronic rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Dr Neil Cheng-Wen Tan |
| 2012 - 2015 | Co-Supervisor | The Role of Surgery and Disease Load in Refractory Chronic Rhinosinusitis | Doctor of Philosophy | Doctorate | Full Time | Mr Ahmed Bassiouni |
| 2012 - 2015 | Co-Supervisor | The Effect of Chitosan Dextran Gel as a Haemostatic and Anti Adhesion Agent in the Central Nervous System and Evaluation of Haemostatic Mechanism of Skeletal Muscle Tissue | Doctor of Philosophy | Doctorate | Full Time | Dr Sukanya Rajiv |
| 2012 - 2014 | Co-Supervisor | The Chronic Rhinosinusitis Microbiome | Doctor of Philosophy | Doctorate | Full Time | Dr Edward John Cleland |
| Date | Role | Committee | Institution | Country |
|---|---|---|---|---|
| 2019 - ongoing | Chair | BHI Strategic Research Directions Committee | Basil Hetzel Institute | Australia |
| 2016 - ongoing | Member | TQEH Human Research Ethics Committee | - | - |
| 2014 - ongoing | Member | The Basil Hetzel Institute Management Committee | The Bsil Hetzel Institute | Australia |
| 2011 - ongoing | Chair | Selection committee for scientist positions | - | - |
| Date | Role | Membership | Country |
|---|---|---|---|
| 2017 - ongoing | Member | American Society of Microbiology | - |
| Date | Role | Editorial Board Name | Institution | Country |
|---|---|---|---|---|
| 2018 - ongoing | Associate Editor | Frontiers in Cellular and Infection Microbiology | Frontiers Journals | United Kingdom |
| 2016 - ongoing | Associate Editor | Sinusitis | - | - |
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