Thao Nguyen

Research Interests

Biochemistry and Cell Biology Cancer Cell Biology Cancer Genetics Cancer Therapy Cardiovascular Medicine and Haematology Cell Biology Haematological Tumours Haematology Cancer Biology and Clinical Oncology Translational Health Outcomes

Dr Thao Nguyen

Senior Lecturer

School of Dentistry

College of Health

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.

Thao is an NHMRC Early Career Research Fellow in stem cell biology, myeloid leukaemias and bone marrow microenvironment. 
Thao performs fundamental, translational and clinical research that aims at targeting cancer relapse-driving stem cell populations by exploring novel therapeutic approaches to prevent cancer relapse. 

Cancer Biology

Date Position Institution name
2017 - 2017 Post-Doctoral Researcher Mesenchymal Stem Cell Laboratory, The University of Adelaide
2016 - ongoing Guest lecturer University of South Australia
2016 - 2017 Post-Doctoral Researcher Mesenchymal Stem Cell Laboratory, The University of Adelaide
2014 - 2015 Research Officer Mesenchymal Stem Cell Laboratory, The University of Adelaide
2008 - 2010 Research Officer University of Adelaide
2004 - 2008 Resarch Officer University of Adelaide
2003 - 2004 Research Officer Numico Research Australia
2003 - 2003 Research Officer Queensland Institute of Medical Research
2002 - 2002 Technical Officer (0.5FTE) Institute of Medical and Veterinary Science

Language Competency
Vietnamese Can read, write, speak, understand spoken and peer review

Date Institution name Country Title
2015 University of South Australia Australia Doctor of Philosophy
2003 University of South Australia Australia Bachelor of Medical and Pharmaceutical Biotechnology

Date Title Institution name Country
1999 Ethnic Accreditation for Teaching South Australia Ethnic School Board Australia

Year Citation
2024 Nguyen, T. M., Joyce, P., Ross, D. M., Bremmell, K., Jambhrunkar, M., Wong, S. S., & Prestidge, C. A. (2024). Combating Acute Myeloid Leukemia via Sphingosine Kinase 1 Inhibitor-Nanomedicine Combination Therapy with Cytarabine or Venetoclax. Pharmaceutics, 16(2), 209-1-209-16.
DOI Scopus7 WoS5 Europe PMC3
2023 Nguyen, T. M., Jambhrunkar, M., Wong, S. S., Ross, D. M., Joyce, P., Finnie, J. W., . . . Prestidge, C. A. (2023). Targeting Acute Myeloid Leukemia Using Sphingosine Kinase 1 Inhibitor-Loaded Liposomes.. Molecular pharmaceutics, 20(8), 3937-3946.
DOI Scopus8 WoS7 Europe PMC6
2022 Lewis, A. C., Pope, V. S., Tea, M. N., Li, M., Nwosu, G. O., Nguyen, T. M., . . . Pitson, S. M. (2022). Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia.. Blood, 139(26), 3737-3751.
DOI Scopus37 WoS32 Europe PMC35
2019 Arthur, A., Nguyen, T. M., Paton, S., Zannettino, A. C. W., & Gronthos, S. (2019). Loss of EfnB1 in the osteogenic lineage compromises their capacity to support hematopoietic stem/progenitor cell maintenance. Experimental Hematology, 69, 43-53.
DOI Scopus14 WoS14 Europe PMC13
2019 Toledo-Flores, D., Williamson, A., Schwarz, N., Fernando, S., Dimasi, C., Witt, T. A., . . . Psaltis, P. J. (2019). Vasculogenic properties of adventitial Sca-1⁺CD45⁺ progenitor cells in mice: a potential source of vasa vasorum in atherosclerosis. Scientific Reports, 9(1), 7286-1-7286-15.
DOI Scopus22 WoS21 Europe PMC20
2018 Arthur, A., Nguyen, T., Paton, S., Klisuric, A., Zannettino, A., & Gronthos, S. (2018). The osteoprogenitor-specific loss of ephrinB1 results in an osteoporotic phenotype affecting the balance between bone formation and resorption. Scientific Reports, 8(1), 12756-1-12756-12.
DOI Scopus16 WoS15 Europe PMC12
2017 Nguyen, T., Arthur, A., Zannettino, A., & Gronthos, S. (2017). EphA5 and EphA7 forward signaling enhances human hematopoietic stem and progenitor cell maintenance, migration, and adhesion via Rac1 activation. Experimental Hematology, 48, 72-78.
DOI Scopus23 WoS21 Europe PMC20
2016 M Nguyen, T., Arthur, A., & Gronthos, S. (2016). Eph/ephrin-mediated mesenchymal stem cell regulation of T-cell activation and function. Journal of Clinical and Cellular Immunology, 7(3), 418-1-418-7.
DOI
2016 Nguyen, T., Arthur, A., Paton, S., Hemming, S., Panagopoulos, R., Codrington, J., . . . Gronthos, S. (2016). Loss of ephrinB1 in osteogenic progenitor cells impedes endochondral ossification and compromises bone strength integrity during skeletal development. Bone, 93, 12-21.
DOI Scopus20 WoS20 Europe PMC15
2016 Nguyen, T., Arthur, A., & Gronthos, S. (2016). The role of Eph/ephrin molecules in stromal–hematopoietic interactions. International Journal of Hematology, 103(2), 145-154.
DOI Scopus21 WoS21 Europe PMC15
2016 Arthur, A., Cakouros, D., Cooper, L., Nguyen, T., Isenmann, S., Zannettino, A., . . . Gronthos, S. (2016). Twist-1 enhances bone marrow mesenchymal stromal cell support of hematopoiesis by modulating CXCL12 expression. Stem Cells, 34(2), 504-509.
DOI Scopus21 WoS21 Europe PMC20
2016 Nguyen, T., Arthur, A., Purton, L., Hayball, J., Zannettino, A., Paton, S., . . . Gronthos, S. (2016). EphB4 enhances bone marrow stromal stem cell-mediated support of haematopoiesis. British journal of haematology, 173(30, S1,S1), 30.
2015 Nguyen, T., Arthur, A., Panagopoulos, R., Paton, S., Hayball, J., Zannettino, A., . . . Gronthos, S. (2015). EphB4 expressing stromal cells exhibit an enhanced capacity for hematopoietic stem cell maintenance. Stem Cells, 33(9), 2838-2849.
DOI Scopus30 WoS31 Europe PMC26
2013 Nguyen, T., Arthur, A., Hayball, J., & Gronthos, S. (2013). Ephb and Ephrin-B interactions mediate human mesenchymal stem cell suppression of activated T-cells. Stem Cells and Development, 22(20), 2751-2764.
DOI Scopus64 WoS63 Europe PMC56
2010 Sasseville, M., Ritter, L., Nguyen, T., Liu, F., Mottershead, D., Russell, D., & Gilchrist, R. (2010). Growth differentiation factor 9 signaling requires ERK1/2 activity in mouse granulosa and cumulus cells. Journal of Cell Science, 123(18), 3166-3176.
DOI Scopus60 WoS54 Europe PMC51
2010 Hayden, M., Tabone, T., Nguyen, T., Coventry, S., Keiper, F., Fox, R., . . . Eglinton, J. (2010). An informative set of SNP markers for molecular characterisation of Australian barley germplasm. Crop and Pasture Science, 61(1), 70-83.
DOI Scopus24 WoS15
2008 Hayden, M., Nguyen, T., Waterman, A., & Chalmers, K. (2008). Multiplex-ready PCR: A new method for multiplexed SSR and SNP genotyping. BMC Genomics, 9(1), WWW 1-WWW 12.
DOI Scopus151 WoS132 Europe PMC74
2008 Hayden, M., Nguyen, T., Waterman, A., McMichael, G., & Chalmers, K. (2008). Application of multiplex-ready PCR for fluorescence-based SSR genotyping in barley and wheat. Molecular Breeding, 21(3), 271-281.
DOI Scopus104 WoS100 Europe PMC44
2007 Hayden, M. J., Nguyen, T. M., & Chalmers, K. J. (2007). Development of a set of sequence tagged microsatellites (STMs) for high throughput, marker assisted selection of the stem rust resistance gene Sr2 in bread wheat. Electronic Journal of Plant Breeding.

Year Citation
2018 Nguyen, T. M., Arthur, A., & Gronthos, S. (2018). EPHA FORWARD SIGNALLINGS ENHANCE HUMAN HAEMATOPOIETIC PROGENITOR CELL MIGRATION AND ADHESION VIA RAC1 ACTIVATION. In JOURNAL OF GENE MEDICINE Vol. 20 (pp. 1 page). Univ Technol Sydney, Sydney, AUSTRALIA: WILEY.
2016 Nguyen, T. M., Arthur, A., Paton, S., Purton, L. E., & Gronthos, S. (2016). EphrinB1 expressing stromal cells exhibit an enhanced capacity for haematopoietic stem cell maintenance. In BRITISH JOURNAL OF HAEMATOLOGY Vol. 173 (pp. 30). British Soc Haematol, Glasgow, SCOTLAND: WILEY-BLACKWELL.
2009 Sasseville, M., Nguyen, T. M., Ritter, L. J., Russell, D. L., & Gilchrist, R. B. (2009). Oocyte/GDF9 Regulation of Granulosa/Cumulus Cell Functions Requires EGF Receptor/MAPK3/1 Signaling.. In BIOLOGY OF REPRODUCTION (pp. 72). Pittsburgh, PA: SOC STUDY REPRODUCTION.
WoS2
2005 Hayden, M., Nguyen, T., & Chalmers, K. (2005). Multiplex-ready markers: A technique for high-throughput, low-cost genotyping on a semi-automated DNA fragment analyser. In 12th Australian Barley Technical Symposium Conference Proceedings, 11-14 September 2005: [CD-ROM] (pp. 9 pages). Hobart, Tasmania: Australian Barley Association.

  • Understanding the biological mechanisms involved in treatment free remission of chronic myeloid leukaemia, NHMRC - Early Career Fellowship, 01/01/2018 - 28/02/2022

Courses I teach

  • BIOL 1051 Physiology Essentials 100 (2025)
  • BIOL 1056 Biomedical Research Training (2025)
  • BIOL 2056 Fetal and Maternal Pathophysiology (2025)
  • BIOL 1007 Biology A (2024)
  • BIOL 1049 Human Physiology 100 (2024)
  • BIOL 1050 Human Physiology 101 (2024)
  • BIOL 1051 Physiology Essentials 100 (2024)
  • BIOL 2016 Genetics (2024)
  • BIOL 2058 Scientific Basis of Clinical Practice (2024)
  • HLTH 2055 UO Fundamentals of Pharmacology (2024)
  • MEDI 2008 UO Pathophysiology (2024)

Programs I'm associated with

  • IBMS - Bachelor of Medical Science
  • Position: Senior Lecturer
  • Email: thao.nguyen01@adelaide.edu.au
  • Alternative Contact: NHMRC Early Career Research Fellow Molecular Therapeutics Laboratory | Centre for Cancer Biology  University of South Australia & SA Pathology HB10-34 Bradley Building | North Terrace | GPO Box 2471 Adelaide SA 5001  T: 08 8302 9067  E: thao.nguyen2@unisa.edu.au  W: www.centreforcancerbiology.org.au

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