Dr Frank Stomski

Research Fellow

Centre for Cancer Biology

College of Health


Year Citation
2022 Tvorogov, D., Thompson-Peach, C. A. L., Foßelteder, J., Dottore, M., Stomski, F., Onnesha, S. A., . . . Lopez, A. F. (2022). Targeting human CALR-mutated MPN progenitors with a neoepitope-directed monoclonal antibody. EMBO Reports, 23(4), e52904-1-e52904-12.
DOI Scopus22 WoS22 Europe PMC21
2018 Tvorogov, D., Thomas, D., Liau, N. P. D., Dottore, M., Barry, E. F., Lathi, M., . . . Lopez, A. F. (2018). Accumulation of JAK activation loop phosphorylation is linked to type I JAK inhibitor withdrawal syndrome in myelofibrosis. Science Advances, 4(11), 1-12.
DOI Scopus46 WoS47 Europe PMC46
2015 Kular, J., Scheer, K., Pyne, N., Allam, A., Pollard, A., Magenau, A., . . . Samuel, M. (2015). A negative regulatory mechanism involving 14-3-3ζ limits signaling downstream of ROCK to regulate tissue stiffness in epidermal homeostasis. Developmental Cell, 35(6), 759-774.
DOI Scopus30 WoS24 Europe PMC27
2012 Cheah, P., Ramshaw, H., Thomas, P., Toyo-oka, K., Xu, X., Martin, S., . . . Schwarz, Q. (2012). Neurodevelopmental and neuropsychiatric behaviour defects arise from 14-3-3ζ deficiency. Molecular Psychiatry, 17(4), 451-466.
DOI Scopus96 WoS93 Europe PMC91
2012 Sandow, J., Jabbour, A., Condina, M., Daunt, C., Stomski, F., Green, B., . . . Ekert, P. (2012). Cytokine receptor signaling activates an IKK-dependent phosphorylation of PUMA to prevent cell death. Cell Death and Differentiation, 19(4), 633-641.
DOI Scopus28 WoS24 Europe PMC24
2010 Lopez, A., Hercus, T., Ekert, P., Littler, D., Guthridge, M., Thomas, D., . . . Parker, M. (2010). Molecular basis of cytokine receptor activation. IUBMB Life, 62(7), 509-518.
DOI Scopus64 WoS58 Europe PMC46
2009 Barry, E., Felquer, F., Powell, J., Biggs, L., Stomski, F., Urbani, A., . . . Guthridge, M. (2009). 14-3-3:Shc scaffolds integrate phosphoserine and phosphotyrosine signaling to regulate phosphatidylinositol 3-kinase activation and cell survival. Journal of Biological Chemistry, 284(18), 12080-12090.
DOI Scopus35 WoS32 Europe PMC29
2008 Hansen, G., Hercus, T., Mc Clure, B., Stomski, F., Dottore, M., Powell, J., . . . Parker, M. (2008). The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation. Cell, 134(3), 496-507.
DOI Scopus270 WoS251 Europe PMC221
2008 Mu, F., Andrews, R., Arthur, J., Munday, A., Cranmer, S., Jackson, S., . . . Berndt, M. (2008). A functional 14-3-3ζ-independent association of PI3-kinase with glycoprotein Ibα, the major ligand-binding subunit of the platelet glycoprotein Ib-IX-V complex. Blood, 111(9), 4580-4587.
DOI Scopus43 WoS37 Europe PMC33
2007 Ramshaw, H., Guthridge, M., Stomski, F., Barry, E., Ooms, L., Mitchell, C., . . . Lopez, A. (2007). The Shc-binding site of the β[c] subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesis. Blood, 110(10), 3582-3590.
DOI Scopus21 WoS18 Europe PMC14
2006 Guthridge, M., Powell, J., Barry, E., Stomski, F., Mc Clure, B., Ramshaw, H., . . . Lopez, A. (2006). Growth factor pleiotropy is controlled by a receptor Tyr/Ser motif that acts as a binary switch. EMBO Journal, 25(3), 479-489.
DOI Scopus72 WoS71 Europe PMC69
2004 Guthridge, M., Barry, E., Felquer, F., Mc Clure, B., Stomski, F., Ramshaw, H., & Lopez, A. (2004). The phosphoserine-585-dependent pathway of the GM-CSF/IL-3/IL-5 receptors mediates hematopoietic cell survival through activation of NF-kB and induction of bcl-2. Blood, 103(3), 820-827.
DOI Scopus67 WoS64 Europe PMC56
2003 Olayioye, M., Guthridge, M., Stomski, F., Lopez, A., Visvader, J., & Lindeman, G. (2003). Threonine 391 phosphorylation of the human prolactin receptor mediates a novel interaction with 14-3-3 proteins. Journal of Biological Chemistry, 278(35), 32929-32935.
DOI Scopus25 WoS23 Europe PMC20
2003 Woodcock, J., Murphy, J., Stomski, F., Berndt, M., & Lopez, A. (2003). The dimeric versus monomeric status of 14-3-3z is controlled by phosphorylation of Ser58 at the dimer interface. Journal of Biological Chemistry, 278(38), 36323-36327.
DOI Scopus157 WoS150 Europe PMC150
2001 Mc Clure, B., Stomski, F., Lopez, A., & Woodcock, J. (2001). Perverted responses of the human granulocyte-macrophage colony-stimulating factor receptor in mouse cell lines due to cross-species b-subunit association. Blood, 98(10), 3165-3168.
DOI Scopus6 WoS6 Europe PMC6
2001 Bagley, C., Woodcock, J., Guthridge, M., Stomski, F., & Lopez, A. (2001). Structural and functional hot spots in cytokine receptors. International Journal of Hematology, 73(3), 299-307.
DOI Scopus10 WoS8 Europe PMC7
2000 Le, F., Stomski, F., Woodcock, J., Lopez, A., & Gonda, T. (2000). The role of disulfide-linked dimerization in interleukin-3 receptor signaling and biological activity. Journal of Biological Chemistry, 275(7), 5124-5130.
DOI Scopus21 WoS19 Europe PMC17
2000 Guthridge, M., Stomski, F., Barry, E., Winnall, W., Woodcock, J., Mc Clure, B., . . . Lopez, A. (2000). Site-specific serine phosphorylation of the IL-3 receptor is required for hemopoietic cell survival. Molecular Cell, 6(1), 99-108.
DOI Scopus71 WoS68 Europe PMC62
1999 Sun, Q., Jones, K., McClure, B., Cambareri, B., Zacharakis, B., Iversen, P., . . . Lopez, A. (1999). Simultaneous antagonism of interleukin-5, granulocyte-macrophage colony-stimulting factor, and interleukin-3 stimulation of human eosinophils by targetting the common cytokine binding site of their receptors. Blood, 94(6), 1943-1951.
DOI Scopus61 WoS52 Europe PMC33
1999 Stomski, F., Dottore, M., Winnall, W., Guthridge, M., Woodcock, J., Bagley, C., . . . Lopez, A. (1999). Identification of a 14-3-3 binding sequence in the common B chain of the granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-5 receptors that is serine-phosphorylated by GM-CSF. Blood, 94(6), 1933-1942.
DOI Scopus46 WoS39 Europe PMC26
1998 Stomski, F. C., Woodcock, J. M., Zacharakis, B., Bagley, C. J., Sun, Q., & Lopez, A. F. (1998). Identification of a cys motif in the common β chain of the interleukin 3, granulocyte-macrophage colony-stimulating factor, and interleukin 5 receptors essential for disulfide-linked receptor heterodimerization and activation of all three receptors. Journal of Biological Chemistry, 273(2), 1192-1199.
DOI Scopus54 WoS50 Europe PMC42
1997 Woodcock, J., McClure, B., Stomski, F., Baglev, C., & Lopez, A. (1997). The mechanism of GM-CSF receptor activation. Experimental Hematology, 25(8), 760.
1997 Iversen, P., Hercus, T., Zacharakis, B., Woodcock, J., Stomski, F., Kumar, S., . . . Lopez, A. (1997). The apoptosis-inducing granulocyte-macrophage colony-stimulating factor (GM-CSF) analog E21R functions through specific regions of the heterodimeric GM-CSF receptor, and requires interleukin-1 beta converting enzyme-like proteases.. Journal of Biological Chemistry, 272(15), 9877-9883.
DOI Scopus12 WoS12 Europe PMC8
1997 Barry, S., Korpelainen, E., Sun, Q., Stomski, F., Moretti, P., Wakao, H., . . . Goodall, G. (1997). Roles of the N and C terminal domains of the interleukin-3 receptor alpha chain in receptor function.. Blood, 89(3), 842-852.
DOI Scopus54 WoS55 Europe PMC28
1996 Qiyu, S., Woodcock, J., Stomski, F., Bagley, C., Goodall, G., Smith, W., . . . Lopez, A. (1996). Monoclonal antibody 7G3 recognises the N-terminal domain of the human IL-3 receptor and functions as a specific IL-3 receptor antagonist. Blood, 87(1), 83-92.
DOI Scopus99 WoS97 Europe PMC62
1987 To, L. B., Juttner, C. A., Stomski, F., Vadas, M. A., & Kimber, R. J. (1987). Immune reconstitution following peripheral blood stem cell autografting.. Bone Marrow Transplantation, 2(1), 111-112.
Scopus25 Europe PMC14

Year Citation
2021 Tvorogov, D., Thompson-Peach, C. A. L., Fosselteder, J., Dottore, M., Stomski, F., Lim, K. S. Y., . . . Lopez, A. F. (2021). A Calreticulin Neoepitope-Directed Monoclonal Antibody Can Overcome JAK Inhibitor Resistance and Block TPO-Independent Megakaryocyte Differentation. In BLOOD Vol. 138 (pp. 4 pages). GA, Atlanta: AMER SOC HEMATOLOGY.
DOI
2018 Tvorogov, D., Thomas, D., Liau, N. P. D., Dottore, M., Barry, E. F., Lathi, M., . . . Lopez, A. F. (2018). Accumulation of JAK Activation-Loop Phosphorylation Promotes Type I JAK Inhibitor Withdrawal Syndrome in Myelofibrosis. In BLOOD Vol. 132 (pp. 4 pages). San Diego, CA: AMER SOC HEMATOLOGY.
DOI

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