Dr Susan Semple

Research Interests

Aboriginal and Torres Strait Islander medicine and treatments Food properties (incl. characteristics and health benefits) Microbiology Natural Products Chemistry Pharmaceutical Sciences Pharmacology & Pharmacy Plant extracts

Dr Susan Semple

Senior Research Fellow

School of Pharmacy and Biomedical Science

College of Health

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

I am a Senior Research Fellow in the Quality Use of Medicines and Pharmacy Research Centre. I have a background in pharmacy and natural products chemistry. My research interests include Australian medicinal and food plants with an emphasis on research which is in partnership with Australian Aboriginal organisations and driven by these organisations. Currently our work is examining the health benefits of, and product development from, some traditional medicinal and food plants. We focus on plants with antimicrobial, skin health and anti-diabetic activities. I am currently a chief investigator on projects funded through the Australian Research Council (ARC) and Medical Research Future Fund (MRFF).
I also collaborate with researchers at the University of Copenhagen in Denmark and Shandong University in China.
I have also conducted research in the areas of complementary medicine use in the community and medication safety

Current research projects include 

Australian Research Council, Linkage Grant (2024-27) Co-research supporting the development of Aboriginal plant knowledges LP220200369 Role: CIA.

Australian Research Council, Linkage Grant (2024-2027) Finding the targets of natural products in complex botanical extracts LP230100225 (Led by Prof David Adelson, University of Adelaide). Role: CI.

Medical Research Future Fund (MRFF) Indigenous Health Research (2023-2025) A bush foods programme to facilitate cultural connections and nutrition knowledges for Aboriginal young people (Led by Michael Watkins, Dept of Rural Health, UniSA). Role CI.

Australian Research Council, Linkage Grant (2026-2028) Mining soil microbiomes for bioactives to combat antimicrobial resistance LP250100437 (Led by A/Prof Rietie Venter, UniSA) Role CI

Date Position Institution name
2014 - ongoing Senior Research Fellow University of South Australia
2005 - 2013 Research Fellow University of South Australia
2002 - 2005 Research Associate University of South Australia
2000 - 2002 Lecturer and research assistant University of South Australia
1993 - 1993 Clinical Trial Coordinator Women's and Children's Hospital

Date Type Title Institution Name Country Amount
2013 Award Business and Higher Education Round Table Outstanding Achievement in Collaboration in Community Engagement - Honourable Mention Business and Higher Education Round Table Australia -
2008 Award University of South Australia. Chancellor’s Awards for Community Engagement University of South Australia Australia -

Date Institution name Country Title
1995 - 2025 University of South Australia Australia PhD
1994 - 1994 University of South Australia Australia Honours
1989 - 1992 University of South Australia Australia B.Pharm

Year Citation
2024 Sebben, D. A., Semple, S. J., Condina, M. R., Dilmetz, B. A., Hoffmann, P., Claudie, D. J., . . . Beattie, D. A. (2024). Extraction and surface activity of Australian native plant extracts: Alphitonia excelsa. Colloids and Interfaces, 8(4), 1-14.
DOI
2024 Liang, C., Ndi, C., Semple, S. J., Buirchell, B., Coriani, S., Moller, B. L., & Staerk, D. (2024). Eremane, viscidane and isozizaene diterpenoids from the leaves of Eremophila rigida and their absolute configurations. Phytochemistry, 219(113972), 1-16.
DOI
2023 Zhao, Y., Li, T., Kjaerulff, L., Venter, H., Coriani, S., Møller, B. L., . . . Staerk, D. (2023). Orthogonal reversed-phase C₁₈ and pentafluorophenyl HPLC separation for phytochemical profiling of serrulatanes in Eremophila denticulata. Journal of Natural Products, 86(12), 2638-2650.
DOI Scopus5 WoS5 Europe PMC1
2023 Liang, C., Ndi, C., Kjaerulff, L., Semple, S., Buirchell, B., Coriani, S., . . . Staerk, D. (2023). Characterization of serrulatane diterpenoids in eremophila phyllopoda subsp. phyllopoda by triple high-resolution α-Glucosidase/PTP1B/radical scavenging profiling, NMR spectroscopy, DFT-GIAO NMR, and electronic circular dichroism calculations. Journal of Natural Products, 86(4), 694-709.
DOI
2023 Zhao, Y., Gericke, O., Li, T., Kjaerulff, L., Kongstad, K. T., Heskes, A. M., . . . Staerk, D. (2023). Polypharmacology-labeled molecular networking: an analytical technology workflow for accelerated identification of multiple bioactive constituents in complex extracts. Analytical Chemistry, 95(9), 4381-4389.
DOI Scopus11 WoS10 Europe PMC8
2023 Liang, C., Zang, J., Ndi, C., Semple, S. J., Buirchell, B., Coriani, S., . . . Staerk, D. (2023). Identification of new PTP1B-inhibiting decipiene diterpenoid esters from eremophila clarkei by high-resolution PTP1B inhibition profiling, enzyme kinetics analysis, and molecular docking. Bioorganic Chemistry, 139(106744), 1-15.
DOI
2023 Pisoni, L. A., Semple, S. J., Liu, S., Sykes, M. J., & Venter, H. (2023). Combined structure- and ligand-based approach for the identification of inhibitors of AcrAB-TolC in Escherichia coli. ACS Infectious Diseases, 9(12), 2504-2522.
DOI Scopus6 Europe PMC4
2023 Guo, T., Chen, Y., Chen, W., Semple, S. J., Gu, X., Polyak, S. W., . . . Ma, S. (2023). Design and synthesis of benzochromene derivatives as AcrB inhibitors for the reversal of bacterial multidrug resistance. European Journal of Medicinal Chemistry, 249(11548), 1-19.
DOI Scopus9 WoS9 Europe PMC6
2022 Lim, R., Ellett, L. M. K., Semple, S., & Roughead, E. E. (2022). The extent of medication-related hospital admissions in Australia: a review from 1988 to 2021. Drug Safety, 45(3), 249-257.
DOI Scopus78 WoS73 Europe PMC58
2022 Chai, W. C., Whittall, J. J., Polyak, S. W., Foo, K., Li, X., Dutschke, C. J., . . . Venter, H. (2022). Cinnamaldehyde derivatives act as antimicrobial agents against Acinetobacter baumannii through the inhibition of cell division. Frontiers in Microbiology, 13(967949), 18 pages.
DOI Scopus20 WoS20 Europe PMC16
2022 Petersen, M. J., Liang, C., Kjaerulff, L., Ndi, C., Semple, S., Buirchell, B., . . . Staerk, D. (2022). Serrulatane diterpenoids from the leaves of Eremophila glabra and their potential as antihyperglycemic drug leads. Phytochemistry, 196(113072), 1-11.
DOI
2022 Bredahl, E. K., Kjaerulff, L., Ndi, C., Semple, S., Buirchell, B., Moller, B. L., & Staerk, D. (2022). Isolation and structure elucidation of caryophyllane sesquiterpenoids from leaves of Eremophila spathulata. Phytochemistry Letters, 47, 156-163.
DOI
2022 Semple, S. J., Staerk, D., Buirchell, B. J., Fowler, R. M., Gericke, O., Kjaerulff, L., . . . Moller, B. L. (2022). Biodiscoveries within the Australian plant genus Eremophila based on international and interdisciplinary collaboration: results and perspectives on outstanding ethical dilemmas. Plant Journal, 111(4), 936-953.
DOI
2022 Rasmussen, L. F., Anton, J., Kjaerulff, L., Zhao, Y., Semple, S. J., Chi, N., . . . Staerk, D. (2022). Serrulatane diterpenoids with unusual side chain modifications from root bark of Eremophila longifolia. Phytochemistry, 203(113408), 1-14.
DOI
2021 Gericke, O., Fowler, R. M., Heskes, A. M., Bayly, M. J., Semple, S. J., Ndi, C. P., . . . Møller, B. L. (2021). Navigating through chemical space and evolutionary time across the Australian continent in plant genus Eremophila. The Plant Journal, 108(2), 555-578.
DOI
2021 Li, P., Chai, W. C., Wang, Z. Y., Tang, K. J., Chen, J. Y., Venter, H., . . . Xiang, L. (2021). Bioactivity-guided isolation of compounds from Sophora flavescens with antibacterial activity against Acinetobacter baumannii. Natural Product Research, 36(17), 4340-4348.
DOI Scopus14 WoS17 Europe PMC9
2021 Petersen, M. J., Lund, X. L., Semple, S. J., Buirchell, B., Franzyk, H., Gajhede, M., . . . Staerk, D. (2021). Reversal of abcg2/bcrp-mediated multidrug resistance by 5,3′,5′-trihydroxy-3,6,7,4′-tetramethoxyflavone isolated from the Australian desert plant eremophila galeata chinnock. Biomolecules, 11(10, article no. 1534), 1-19.
DOI
2021 Jaunay, E. L., Dhillon, V. S., Semple, S. J., Simpson, B. S., Ghetia, M., Deo, P., & Fenech, M. (2021). Genotoxicity of advanced glycation end products in vitro is influenced by their preparation temperature, purification, and cell exposure time. Mutagenesis, 36(6), 445-455.
DOI Scopus1 WoS1 Europe PMC1
2021 Hu, S., Chai, W. C., Xu, L., Li, S., Jin, C., Zhu, R., . . . Xiang, L. (2021). Catecholic alkaloid sulfonates and aromatic nitro compounds from Portulaca oleracea and screening of their anti-inflammatory and anti-microbial activities. Phytochemistry, 181(112587), 1-11.
DOI Scopus17 WoS15 Europe PMC4
2020 Jaunay, E. L., Dhillon, V. S., Semple, S. J., Simpson, B. S., Deo, P., & Fenech, M. (2020). Can a digital slide scanner and viewing technique assist the visual scoring for the cytokinesis-block micronucleus cytome assay?. Mutagenesis, 35(4), 311-317.
DOI Scopus6 WoS6 Europe PMC4
2020 Gu, X., Pisoni, L. A., Wang, Y., Song, D., Sykes, M. J., Qin, Y., . . . Ma, S. (2020). Design and synthesis of novel 4-substituted quinazoline-2-carboxamide derivatives targeting AcrB to reverse the bacterial multidrug resistance. Bioorganic Chemistry, 105(104394), 1-16.
DOI Scopus9 WoS10 Europe PMC6
2020 Chai, W. C., Whittall, J. J., Song, D., Polyak, S. W., Ogunniyi, A. D., Wang, Y., . . . Venter, H. (2020). Antimicrobial action and reversal of resistance in MRSA by difluorobenzamide derivatives targeted at FtsZ. Antibiotics (Basel), 9(12), 1-22.
DOI Scopus14 WoS13 Europe PMC9
2020 Hans, A. P., Ndi, C., Semple, S. J., Buirchell, B., Moller, B. L., & Staerk, D. (2020). PTP1B-inhibiting branched-chain fatty acid dimers from eremophila oppositifolia subsp. angustifolia Identified by high-resolution PTP1B inhibition profiling and HPLC-PDA-HRMS-SPE-NMR analysis. Journal of Natural Products, 83(5), 1598-1610.
DOI
2020 Kjaerulff, L., Jensen, A. B. J., Ndi, C., Semple, S., Moller, B. L., & Staerk, D. (2020). Isolation, structure elucidation and PTP1B inhibitory activity of serrulatane diterpenoids from the roots of Myoporum insulare. Phytochemistry Letters, 39, 49-56.
DOI
2020 Kim, S., Semple, S. J., Simpson, B. S., & Deo, P. (2020). Antioxidant and Antiglycation Activities of Syzygium paniculatum Gaertn and Inhibition of Digestive Enzymes Relevant to Type 2 Diabetes Mellitus. Plant Foods for Human Nutrition, 75(4), 621-627.
DOI Scopus16 WoS12 Europe PMC10
2019 Biva, I. J., Ndi, C. P., Semple, S. J., & Griesser, H. J. (2019). Antibacterial performance of terpenoids from the Australian plant Eremophila lucida. Antibiotics, 8(2, article no. 63), 1-8.
DOI
2019 Jæger, D., O Leary, M. C., Weinstein, P., Møller, B. L., & Semple, S. J. (2019). Phytochemistry and bioactivity of Acacia sensu stricto (Fabaceae: Mimosoideae). Phytochemistry Reviews, 18(1), 129-172.
DOI Scopus14 WoS12
2018 Jæger, D., Simpson, B., Ndi, C., Jäger, A., Crocoll, C., Møller, B., . . . Semple, S. (2018). Biological activity and LC-MS/MS profiling of extracts from the Australian medicinal plant Acacia ligulata (Fabaceae). Natural Product Research, 32(5), 576-581.
DOI Scopus8 WoS6 Europe PMC2
2018 Bi, F., Ji, S., Venter, H., Liu, J., Semple, S. J., & Ma, S. (2018). Substitution of terminal amide with 1H-1,2,3-triazole: Identification of unexpected class of potent antibacterial agents. Bioorganic and medicinal chemistry letters, 28(5), 884-891.
DOI Europe PMC16
2018 Mahendran, V. J., Stringer, A. M., Semple, S. J., Song, Y., & Garg, S. (2018). Advances in the use of anti-inflammatory agents to manage chemotherapy-induced oral and gastrointestinal mucositis. Current pharmaceutical design, 24(14), 1518-1532.
DOI Scopus25 WoS20 Europe PMC19
2018 Liu, J., Ma, R., Bi, F., Zhang, F., Hu, C., Venter, H., . . . Ma, S. (2018). Novel 5-methyl-2-phenylphenanthridium derivatives as FtsZ-targeting antibacterial agents from structural simplification of natural product sanguinarine. Bioorganic and medicinal chemistry letters, 28(10), 1825-1831.
DOI Europe PMC13
2017 Liu, F., Venter, H., Bi, F., Semple, S. J., Liu, J., Jin, C., & Ma, S. (2017). Synthesis and antibacterial activity of 5-methylphenanthridium derivatives as FtsZ inhibitors. Bioorganic and Medicinal Chemistry Letters, 27(15), 3399-3402.
DOI Europe PMC12
2017 Jæger, D., Ndi, C., Crocoll, C., Simpson, B., Khakimov, B., Guzman-Genuino, R., . . . Semple, S. (2017). Isolation and Structural Characterization of Echinocystic Acid Triterpenoid Saponins from the Australian Medicinal and Food Plant Acacia ligulata. Journal of Natural Products, 80(10), 2692-2698.
DOI Scopus18 WoS17 Europe PMC12
2017 Dueholm, B., Bruce, D., Weinstein, P., Semple, S., Møller, B., & Weiner, J. (2017). Spatial analysis of root hemiparasitic shrubs and their hosts: a search for spatial signatures of above- and below-ground interactions. Plant Ecology, 218(2), 185-196.
DOI Scopus5 WoS6 Europe PMC1
2017 Dueholm, B., Bruce, D., Weinstein, P., Semple, S., Møller, B. L., & Weiner, J. (2017). Erratum to: Spatial analysis of root hemiparasitic shrubs and their hosts: a search for spatial signatures of above- and below-ground interactions (Plant Ecol, 10.1007/s11258-016-0676-8). Plant Ecology, 218(2), 197-199.
DOI
2017 Bi, F., Guo, L., Wang, Y., Venter, H., Semple, S. J., Liu, F., & Ma, S. (2017). Design, synthesis and biological activity evaluation of novel 2,6-difluorobenzamide derivatives through FtsZ inhibition. Bioorganic and medicinal chemistry letters, 27(4), 958-962.
DOI Scopus31 Europe PMC20
2017 Bendikov, M. Y., Miners, J. O., Simpson, B. S., Elliot, D. J., Semple, S. J., Claudie, D. J., . . . Sykes, M. J. (2017). In vitro metabolism of the anti-inflammatory clerodane diterpenoid polyandric acid A and its hydrolysis product by human liver microsomes and recombinant cytochrome P450 and UDP-glucuronosyltransferase enzymes. Xenobiotica, 47(6), 461-469.
DOI
2016 Biva, I. J., Ndi, C. P., Griesser, H., & Semple, S. (2016). Antibacterial constituents of eremophila alternifolia: an Australian aboriginal traditional medicinal plant. Journal of ethnopharmacology, 182, 1-9.
DOI
2016 Simpson, B., Bulone, V., Semple, S., Booker, G., McKinnon, R., & Weinstein, P. (2016). Arid awakening: new opportunities for Australian plant natural product research. Rangeland Journal, 38(5), 467-478.
DOI Scopus4 WoS4
2016 Deo, P., Hewawasam, E., Karakoulakis, A., Claudie, D., Nelson, R., Simpson, B., . . . Semple, S. (2016). In vitro inhibitory activities of selected Australian medicinal plant extracts against protein glycation, angiotensin converting enzyme (ACE) and digestive enzymes linked to type II diabetes. BMC Complementary and Alternative Medicine, 16(1), 1-11.
DOI Scopus38 WoS30 Europe PMC15
2016 Roughead, E. E., Semple, S. J., & Rosenfeld, E. (2016). The extent of medication errors and adverse drug reactions throughout the patient journey in acute care in Australia. International journal of evidence-based healthcare, 14(3), 113-122.
DOI
2015 Mon, H., Christo, S., Ndi, C., Jasieniak, M., Rickard, H., Hayball, J., . . . Semple, S. (2015). Serrulatane Diterpenoid from Eremophila neglecta Exhibits Bacterial Biofilm Dispersion and Inhibits Release of Pro-inflammatory Cytokines from Activated Macrophages. Journal of Natural Products, 78(12), 3031-3040.
DOI Scopus22 WoS22 Europe PMC18
2015 Simpson, B. S., Luo, X., Wang, J., Song, Y., Claudie, D. J., Garg, S., . . . Semple, S. J. (2015). Development and evaluation of a topical anti-inflammatory preparation containing Dodonaea polyandra extract. Journal of Pharmacy and Pharmaceutical Sciences, 18(4), 578-599.
DOI Scopus8 WoS7 Europe PMC4
2015 Ndi, C. P., Sykes, M. J., Claudie, D. J., McKinnon, R. A., Semple, S. J., & Simpson, B. S. (2015). Antiproliferative aporphine alkaloids from Litsea glutinosa and ethnopharmacological relevance to Kuuku I'yu traditional medicine. Australian journal of chemistry, 69(2), 145-151.
DOI
2014 Simpson, B., Luo, X., Costabile, M., Caughey, G., Wang, J., Claudie, D., . . . Semple, S. (2014). Polyandric acid A, a clerodane diterpenoid from the Australian medicinal plant Dodonaea polyandra, attenuates pro-inflammatory cytokine secretion in vitro and in vivo. Journal of Natural Products, 77(1), 85-91.
DOI Scopus23 WoS22 Europe PMC12
2013 Locher, C., Semple, S. J., & Simpson, B. S. (2013). Traditional Australian Aboriginal medicinal plants: an untapped resource for novel therapeutic compounds?. Future medicinal chemistry, 5(7), 733-736.
DOI
2013 Simpson, B., Claudie, D., Smith, N., McKinnon, R. A., & Semple, S. J. (2013). Learning from both sides: experiences and opportunities in the investigation of Australian Aboriginal medicinal plants. Journal of pharmaceutical policy and practice, 16(2), 259-271.
2012 Anakok, O., Ndi, C., Barton, M., Griesser, H., & Semple, S. (2012). Antibacterial spectrum and cytotoxic activities of serrulatane compounds from the Australian medicinal plant Eremophila neglecta. Journal of Applied Microbiology, 112(1), 197-204.
DOI WoS35 Europe PMC17
2012 Simpson, B. S., Claudie, D. J., Smith, N. M., McKinnon, R. A., & Semple, S. J. (2012). Rare, seven-membered cyclic ether labdane diterpenoid from Dodonaea polyandra. Phytochemistry, 84, 141-146.
DOI
2012 Ndi, C. P., Semple, S. J., & Griesser, H. J. (2012). Instability of antibacterial serrulatane compounds from the Australian plant species Eremophila duttonii. Australian journal of chemistry, 65(1), 20-27.
DOI
2011 Simpson, B., Claudie, D., Gerber, J., Pyke, S., Wang, J., McKinnon, R., & Semple, S. (2011). In vivo activity of benzoyl ester clerodane diterpenoid derivatives from Dodonaea polyandra. Journal of Natural Products, 74(4), 650-657.
DOI Scopus28 WoS26 Europe PMC15
2011 Simpson, B. S., Claudie, D. J., Smith, N. M., Gerber, J. P., McKinnon, R. A., & Semple, S. J. (2011). Flavonoids from the leaves and stems of Dodonaea polyandra: a Northern Kaanju medicinal plant. Phytochemistry, 72(14-15), 1883-1888.
DOI
2011 Griesser, H. J., Vasilev, K., Ys, H., Ndi, C., Griesser, S. S., Jasieniak, M., . . . Semple, S. (2011). Protecting polymer surfaces against bacterial adhesion and biofilm formation. European cells and materials, 21(S2), 14.
2010 Simpson, B., Claudie, D., Smith, N. M., Wang, J., McKinnon, R. A., & Semple, S. J. (2010). Evaluation of the anti-inflammatory properties of Dodonaea polyandra, a Kaanju traditional medicine. Journal of ethnopharmacology, 132(1), 340-343.
DOI Scopus33 Europe PMC14
2010 Griesser, H. J., Vasilev, K., Ndi, C., Ys, H., Griesser, S., & Semple, S. (2010). Strategies for combating infection at biomedical device surfaces. Wound repair and regeneration, 18(4), A74.
DOI
2009 Roughead, E. E., & Semple, S. J. (2009). Medication safety in acute care in Australia : where are we now? Part 1 : a review of the extent and causes of medication problems 2002-2008. Australia and New Zealand health policy, 6(no. 1, article no. 18), 1-12.
DOI
2009 Leong, E. M., Semple, S. J., Angley, M., Siebert, W., Petkov, J., & McKinnon, R. A. (2009). Complementary and alternative medicines and dietary interventions in multiple sclerosis: what is being used in South Australia and why?. Complementary therapies in medicine, 17(4), 216-223.
DOI
2009 Semple, S. J., & Roughead, E. E. (2009). Medication safety in acute care in Australia : where are we now? Part 2 : a review of strategies and activities for improving medication safety 2002-2008. Australia and New Zealand health policy, 6(1), article no. 24.
DOI
2009 Goh, L. Y., Vitry, A. I., Semple, S. J., Esterman, A., & Luszcz, M. A. (2009). Self-medication with over-the-counter drugs and complementary medications in South Australia's elderly population. BMC complementary and alternative medicine, 9, article no. 42(9), 10-11.
DOI Scopus102 WoS86 Europe PMC66
2008 Vitry, A. I., Phillips, S., & Semple, S. J. (2008). Quality and availability of consumer information on heart failure in Australia. BMC health services research, 8(1), article no. 255.
DOI
2008 Griesser, H. J., Ys, H., Ndi, C. P., Britcher, L. G., Vasilev, K. A., Jasieniak, M., . . . Semple, S. J. (2008). Combating infections at biomedical implants and devices by antibacterial coatings. Chemistry in Australia, 75(11), 5-8.
2007 Ndi, C. P., Semple, S. J., Griesser, H. J., & Barton, M. D. (2007). Antimicrobial activity of some Australian plant species from the genus Eremophila. Journal of basic microbiology.
DOI
2007 Angley, M. T., Semple, S. J., Hewton, C. E., Paterson, F., & McKinnon, R. A. (2007). Children and autism. Part 2 : management with complementary medicines and dietary interventions. Australian family physician.
2007 Ndi, C., Semple, S., Griesser, H., Pyke, S., & Barton, M. (2007). Antimicrobial compounds from Eremophila serrulata. Phytochemistry, 68(21), 2684-2690.
DOI Scopus52 WoS48 Europe PMC21
2007 Ndi, C., Semple, S., Griesser, H., Pyke, S., & Barton, M. (2007). Antimicrobial compounds from the Australian desert plant Eremophila neglecta. Journal of Natural Products, 70(9), 1439-1443.
DOI Scopus51 WoS44 Europe PMC26
2006 Semple, S., Hotham, E., Rao, D., Martin, K., Smith, C., & Bloustien, G. (2006). Community pharmacists in Australia: barriers to information provision on complementary and alternative medicines. Pharmacy World & Science, 28(6), 366-373.
DOI WoS64 Europe PMC47
2005 Smith, C. A., Martin, K. L., Hotham, E. D., Semple, S. J., Bloustien, G. F., & Rao, D. (2005). Naturopaths practice behaviour : provision and access to information on complementary and alternative medicines. BMC complementary and alternative medicine, 5(1).
DOI
2005 Semple, S. J., & Roughead, E. E. (2005). Reducing medication error and harm: an important role for pharmacy in medication safety and safer systems. Australian Pharmacist.
2005 Roughead, E. E., Semple, S. J., & Vitry, A. I. (2005). Pharmaceutical care services: a systemic review of published studies 1990 to 2003, examining effectiveness in improving patient outcomes. International journal of pharmacy practice, 13(1), 53-70.
DOI
2004 Roughead, L., & Semple, S. (2004). Building a safer system for Australian health care: essential role of clinical pharmacy services. Journal of Pharmacy Practice and Research, 34(2), 88-89.
2003 Roughead, E. E., Semple, S. J., & Gilbert, A. L. (2003). Quality use of medicines in aged-care facilities in Australia. Drugs and aging, 20(9), 643-653.
DOI
2003 Runciman, W., Roughead, E., Semple, S., & Adams, R. (2003). Adverse drug events and medication errors in Australia. International Journal for Quality in Health Care, 15(Supplement 1), i49-i59.
DOI Scopus300 WoS223 Europe PMC185
2002 Szeto, M. P., Semple, S. J., & Roughead, E. E. (2002). A study of complementary medicine advertising in Australia. Australian Pharmacist.
2002 Semple, S. J., Byrne, M. J., & Coulthard, K. (2002). Complemantary medicine use during pregnancy. Interviews with 48 women in a hospital antenatal ward.. Australian Pharmacist.
2002 Palombo, E., & Semple, S. J. (2002). Antibacterial activity of Australian plant extracts against methicillin-resistant staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). Journal of Basic Microbiology.
2001 Palombo, E., & Semple, S. J. (2001). Antibacterial activity of traditional Australian medicinal plants. Journal of Ethnopharmacology, 77(2-3), 151-157.
DOI
2001 Semple, S., Pyke, S., Reynolds, G., & Flower, R. (2001). In vitro antiviral activity of the anthraquinone chrysophanic acid against poliovirus. Antiviral Research, 49(3), 169-178.
DOI Scopus144 WoS112 Europe PMC67
1999 Semple, S., Nobbs, S., Pyke, S., Reynolds, G., & Flower, R. (1999). Antiviral flavanoid from Pterocaulon sphacelatum, an Australian Aboriginal medicine. Journal of Ethnopharmacology, 68(1-3), 283-288.
DOI Scopus73 WoS49 Europe PMC25
1998 Semple, S. J., Reynolds, G. D., Oleary, M., & Flower, R. L. (1998). Screening of Australian medicinal plants for antiviral activity. Journal of Ethnopharmacology, 60(2), 163-172.
DOI
1998 Reynolds, G. D., Flower, R. L., Oleary, M., & Semple, S. J. (1998). Screening of Australian Medicinal Plants for Antiviral Activity. Journal of Ethnopharmacology.

Year Citation
2009 Ys, H., Ndi, C., Semple, S. J., & Griesser, H. J. (2009). Antibacterial coatings: covalently immobilized serrulatane diterpenes isolated from Australian plants of the genus eremophila. In Proceedings of the World Biomaterials Congress 2008 Vol. 2 (pp. 697). US: Curran Associates Inc.
2007 Angley, M. T., Hewton, C. E., Paterson, F., Semple, S. J., Ellis, D., Chan, W. S. W., . . . Stanek, J. (2007). Quality use of conventional and complementary medicines in autism. In A world of possibilities. UK: Autismeforeningen i Norge.
2006 Paterson, F., Hewton, C. E., Angley, M. T., & Semple, S. J. (2006). Autism and complementary medicines: what is the evidence?. In Proceedings of the australasian pharmaceutical science association annual conference 2006. NA: APSA.
2006 Hewton, C. E., Paterson, F., Semple, S. J., & Angley, M. T. (2006). Autism and complementary medicines: what is being used and why?. In Annual conference of the APSA. NA: APSA.
2002 Roughead, E. E., & Semple, S. J. (2002). Safety and Quality Council - Second National Report on Patient Safety. In Improving Medication Safety. Canberra: Commonwealth Department of Health and Ageing.
2001 Szeto, P., Semple, S. J., & Roughead, E. E. (2001). A Study of Complementary Medicine Advertising in Australia. In Proceedings of the Australasian Pharmaceutical Science Association. Melbourne, Victoria, Australia: APSA.
2001 Semple, S. J., & Barton, M. D. (2001). Building Bridges with Traditional Knowledge II. In The Society of Economic Botany, 42nd Annual Meeting.
2000 Semple, S. J. (2000). Herbal medicines for gastro intestinal conditions. In 18th Asian Congress of Pharmaceutical Sciences and 6th Pharmacy Australian Congress.
1999 Semple, S. J., Nakata, M., & McKinnon, R. A. (1999). Development of an elective health subject to enhance curricula inclusive of indigenous experience. In Australasian Pharmaceutical Science Association 1999 Conference. Western Australia: ASCEPT.
1998 Semple, S. J., & Flower, R. L. (1998). The antiviral activity of Australian Aboriginal medicinal plant Dianella longifolia (Liliaeceae). In ASCEPT. ASCEPT.
1997 Reynolds, G. D., Flower, R. L., & Semple, S. J. (1997). Screening of some Australian Medicinal plants for antiviral activity. In Microbiology Australia.

Year Citation
2013 Semple, S. J., Simpson, B. S., McKinnon, R. A., Claudie, D., Gerber, J. P., Wang, J., & Moreton, G. S. (2013). US 20130053437, Anti-inflammatory compounds.
2009 Griesser, H. J., Ndi, C. P., Semple, S. J., & Ys, H. (2009). WO2009094707, Antimicrobial surfaces.

  • Finding the targets of natural products in complex botanical extracts, Shanxi Zhendong Pharmaceuticals Co Ltd, 01/01/2024 - 31/12/2026

  • Finding the targets of natural products in complex botanical extracts, ARC - Linkage Project, 01/01/2024 - 31/12/2026

Date Role Research Topic Program Degree Type Student Load Student Name
2025 Principal Supervisor - Doctor of Philosophy Doctorate Full Time Mrs Oluwakemi Taiwo
2025 Principal Supervisor - Doctor of Philosophy Doctorate Full Time Vivek Jayasimhan
2024 Co-Supervisor - Doctor of Philosophy Doctorate Full Time Mr Michael Watkins
2023 Co-Supervisor - Doctor of Philosophy Doctorate Full Time Miss Sida Liu

Date Title Engagement Type Institution Country
2004 - ongoing Working with Kuuku I'yu Traditional Custodians in the investigation of food and medicine plants Public Community Engagement Chuulangun Aboriginal Corporation Australia

Date Institution Department Organisation Type Country
2013 - ongoing University of South Australia Quality Use of Medicines and Pharmacy Research Centre Business and professional Australia

Date Topic Presented at Institution Country
2024 - ongoing Research on medicinal plants in Australia, opportunities perspectives and challenges 4th International Development Forum on Pharmacology of Natural Products and Traditional Medicines International Development Forum on Pharmacology of Natural Products and Traditional Medicines and Chinese Pharmacological Society China
2022 - ongoing Co-research to understand the potential health and wellbeing effects of bush foods & medicines. Indigenous Foods: Ingredients for Life Nutrition Society of Australia Australia
2021 - ongoing Experiences with the Patent System – A collaborative approach. - World Intellectual Property Organization Switzerland
2021 - ongoing Collaborative approach taken to translate Kuuku I’yu food and medicine plants Knowledge Commercialisation Australasia (KCA) Annual Conference Knowledge Commercialisation Australasia Australia
2021 - ongoing A partnership in understanding the potential health benefits of Kuuku I’yu food and medicine plants TTO’s & Indigenous IP: Principles, Policies and Engagement University of Otago New Zealand

Date Title Type Institution Country
2021 - ongoing ARC Detailed Assessor Grant Assessment Australian Research Council Australia

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