Dr Stuart Mills

Senior Research Fellow

Future Industries Institute

Future Industries Institute

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Available For Media Comment.


Dr Stuart Mills is a Senior Research Fellow within the Future Industries Institute at UniSA. The main area of his research is the development of stem cell therapies for hard-to-heal wounds, with a particular focus on diabetic related foot ulcers (DRFU).  His work is heavily focused on industry engagement and has worked with numerous industry partners including, Athersys (USA), Regenesys (Belgium), Cynata (Australia), Carina Biotech (Australia), Tekcyte (Australia) and Tissue Repair (Australia).His research career began at the University of Manchester (UK) where he undertook his PhD, investigating the use if photodynamic therapy to reduced scarring, in collaboration with Galderma (France).  Since moving to Australia, he had continued his wound healing and cancer research at the Peter MacCallum Cancer Centre and the Women’s and Children’s Health Research Institute (Adelaide) before moving to UniSA.He has worked on projects in the Cell Therapies Manufacturing Cooperative Research Centre (CTM-CRC) when he was able to help develop a stem cell therapeutic that accelerated healing in DRFUs.  This work was developed in the lab, taken through preclinical work and has successfully been through phase I human clinical trials and has produced two patents.   It has been taken on by the industry partner Cynata who are looking to progress through phase II clinical trials.https://www.biospace.com/press-releases/cyp-006tk-demonstrates-safety-and-efficacy-in-dfu-clinical-trialHe has also worked with another industry partner from the CTM CRC, Carina Biotech when he carried out preclinical work in the development of a CAR T-cell therapy for the treatment of colo-rectal cancer.  This work has also progressed into phase I human clinical trials, which are currently underway.https://www.carinabiotech.com/press-release-carina-biotech-doses-first-patient-in-phase-1-2a-clinical-trial/He has also work on project in the ARC IDEAL Hub and his preclinical studies over the past two years, with industry partner Tissue Repair, have also led to an FDA application and the treatment is now undergoing a phase I clinical trial for the treatment of venous leg ulcers. He has brought in grant funding from academia and has published his work (h-index 17) in high grade journals, which have been cited over 2500 times.  Last year he won the Future Industries Institute EMCR award (2024) and has also won prizes for his writing and presentations. He is also on the committee of the Australian Wound and Tissue Repair Society (AWTRS).

Wound Healing

Inflammation

Biomaterials

Stem Cells

Diabetes

Date Position Institution name
2026 - ongoing Senior Research Fellow Adelaide University
2025 - 2025 Senior Research Fellow University of South Australia
2012 - 2014 Research Officer Women's and Children's Health Research Institute
2008 - 2011 Research Associate Peter MacCallum Cancer Centre

Date Type Title Institution Name Country Amount
2024 Award 2024 Future Industries Institute Director's EMCR Award University of South Australia Australia -
2020 Award Supervision and Mentoring Award ARC Ideal Hub Australia -
2016 Award Coloplast Biatain Literary Award Coloplast Australia 1000

Date Institution name Country Title
2007 - 2011 University of Manchester United Kingdom PhD
2007 - 2007 University of Manchester United Kingdom MPhil

Year Citation
2025 Guan, B., Mills, S., Liu, T., Yang, C. T., & Priest, C. (2025). Integration of 3D-Printed Micro/Nanostructures with Interdigitated Electrodes for Low-Matrix-Effect Sensing. ACS Applied Materials and Interfaces, 17(26), 38678-38688.
DOI
2023 Bandara, V., Foeng, J., Gundsambuu, B., Norton, T. S., Napoli, S., McPeake, D. J., . . . Barry, S. C. (2023). Pre-clinical validation of a pan-cancer CAR-T cell immunotherapy targeting nfP2X7.. Nat Commun, 14(1), 1-17.
DOI Scopus20 WoS21 Europe PMC18
2023 Mills, S. J., Kirby, G. T., Hofma, B. R., Smith, L. E., Statham, P., Vaes, B., . . . Cowin, A. J. (2023). Delivery of multipotent adult progenitor cells via a functionalized plasma polymerized surface accelerates healing of murine diabetic wounds. Frontiers In Bioengineering And Biotechnology, 11(1213021), 1-13.
DOI Scopus4 WoS4 Europe PMC2
2022 Mills, S. J., Ahangar, P., Thomas, H. M., Hofma, B. R., Murray, R. Z., & Cowin, A. J. (2022). Flightless I Negatively Regulates Macrophage Surface TLR4, Delays Early Inflammation, and Impedes Wound Healing. Cells, 11(14), 2192-1-2192-17.
DOI Scopus13 WoS13 Europe PMC13
2021 Ahangar, P., Mills, S. J., Smith, L. E., Strudwick, X. L., Ting, A. E., Vaes, B., & Cowin, A. J. (2021). Treatment of murine partial thickness scald injuries with multipotent adult progenitor cells decreases inflammation and promotes angiogenesis leading to improved burn injury repair. Wound Repair Regen, 29(3), 1-10.
DOI Scopus1
2021 Thomas, H. M., Ahangar, P., Fitridge, R., Kirby, G. T. S., Mills, S. J., & Cowin, A. J. (2021). Plasma-polymerized pericyte patches improve healing of murine wounds through increased angiogenesis and reduced inflammation. Regenerative Biomaterials, 8(4), 1-12.
DOI Scopus5 WoS5 Europe PMC4
2020 Ahangar, P., Mills, S. J., Smith, L. E., Strudwick, X. L., Ting, A. E., Vaes, B., & Cowin, A. J. (2020). Human multipotent adult progenitor cell-conditioned medium improves wound healing through modulating inflammation and angiogenesis in mice. Stem Cell Research and Therapy, 11(1), 299-1-299-16.
DOI Scopus30 WoS27 Europe PMC20
2020 Thomas, H. M., Ahangar, P., Hofma, B. R., Strudwick, X. L., Fitridge, R., Mills, S. J., & Cowin, A. J. (2020). Attenuation of flightless I increases human pericyte proliferation, migration and angiogenic functions and improves healing in murine diabetic wounds. International Journal of Molecular Sciences, 21(16), 1-15.
DOI Scopus14 WoS13 Europe PMC12
2020 Ahangar, P., Mills, S. J., & Cowin, A. J. (2020). Mesenchymal stem cell secretome as an emerging cell-free alternative for improving wound repair. International Journal of Molecular Sciences, 21(19), 1-15.
DOI Scopus148 WoS130 Europe PMC115
2020 Ahangar, P., Mills, S. J., Smith, L. E., Gronthos, S., & Cowin, A. J. (2020). Human gingival fibroblast secretome accelerates wound healing through anti-inflammatory and pro-angiogenic mechanisms. npj Regenerative Medicine, 5(1), 1-10.
DOI Scopus70 WoS60 Europe PMC44
2020 Kirby, G. T. S., Mills, S. J., Mueller, T. E., Ting, A. E., Cowin, A. J., Michelmore, A., & Smith, L. (2020). Improved recovery of cryopreserved cell monolayers with a hyaluronic acid surface treatment. Biointerphases, 15(6, article no. 061015), 1-9.
DOI Scopus2 WoS2 Europe PMC1
2017 Kirby, G. T. S., Mills, S. J., Vandenpoel, L., Pinxteren, J., Ting, A., Short, R. D., . . . Smith, L. E. (2017). Development of advanced dressings for the delivery of progenitor cells. ACS applied materials and interfaces, 9(4), 3445-3454.
DOI Scopus13 WoS13 Europe PMC11
2017 Thomas, H. M., Cowin, A. J., & Mills, S. J. (2017). The importance of pericytes in healing: wounds and other pathologies. International journal of molecular sciences, 18(1129), 1-14.
DOI Scopus57 WoS55 Europe PMC46
2016 Sinha, D., Chong, L., George, J., Schlueter, H., Monchgesang, S., Mills, S., . . . Kaur, P. (2016). Pericytes promote malignant ovarian cancer progression in mice and predict poor prognosis in serous ovarian cancer patients. Clinical cancer research, 22(7), 1813-1824.
DOI
2015 Mills, S., Zhuang, L., Arandjelovic, P., Cowin, A., & Kaur, P. (2015). Effects of human pericytes in a murine excision model of wound healing. Experimental dermatology, 24(11), 881-882.
DOI Scopus8 WoS9 Europe PMC6
2015 Kirby, G., Mills, S., Cowin, A. J., & Smith, L. (2015). Stem cells for cutaneous wound healing. BioMed research international, 2015, article no. 285869, 1-11.
DOI Scopus83 WoS65 Europe PMC54
2014 Mills, S. J., Farrar, M. D., Ashcroft, G. S., Griffiths, C. E. M., Hardman, M. J., & Rhodes, L. E. (2014). Topical photodynamic therapy following excisional wounding of human skin increases production of transforming growth factor-β3 and matrix metalloproteinases 1 and 9, with associated improvement in dermal matrix organization. British journal of dermatology, 171(1), 55-62.
DOI
2013 Mills, S. J., Cowin, A. J., & Kaur, P. (2013). Pericytes, Mesenchymal Stem Cells and the wound healing process. Cells, 2(3), 621-634.
DOI Scopus97 Europe PMC79
2013 Ruzehaji, N., Mills, S., Melville, E., Arkell, R., Fitridge, R., & Cowin, A. (2013). The influence of Flightless I on toll-like-receptor-mediated inflammation in a murine model of diabetic wound healing. BioMed Research International, 2013(389792), 389792-1-389792-9.
DOI Scopus18 WoS17 Europe PMC17
2013 Mills, S. J., & Cowin, A. J. (2013). MicroRNAs and their roles in wound repair and regeneration. Wound practice & research, 21(1), 26-40.
WoS5

Year Citation
2016 Smith, L., Michelmore, A. P., Kirby, G. T. S., Cowin, A. J., Mills, S. J., & Short, R. D. (2016). WO2016131096, Methods and products for delivering cells.
  • Fucoidan in CAR-T Cell Manufacture, Marine Bioproducts CRC, 05/06/2023 - 05/12/2023

  • Development of a new pericyte therapy for the treatment of diabetic wounds, Diabetes Australia Research Trust (DART) - General Grant, 01/01/2018 - 31/12/2018

Date Role Research Topic Program Degree Type Student Load Student Name
2025 Co-Supervisor - Doctor of Philosophy Doctorate Full Time Yohannes Wondmkun
2023 Co-Supervisor - Doctor of Philosophy Doctorate Full Time Eleonora Vittoria Allievi

Date Role Committee Institution Country
2018 - ongoing Representative Committee of the Australian Woud and Tissue Repair Society Australian Woud and Tissue Repair Society Australia

Date Role Membership Country
2018 - ongoing Member AWTRS Committee -

Date Title Engagement Type Institution Country
2025 - ongoing AWTRS Conference Organising Committee Scientific Community Engagement Australian Wound and Tissue Repair Society Australia
2023 - ongoing AWTRS Conference Organising Committee Scientific Community Engagement Australian Wound and Tissue Repair Society Australia
2021 - ongoing AWTRS Conference Organising Committee Scientific Community Engagement Australian Wound and Tissue Repair Society Australia

Date Event Name Event Type Institution Country
2025 - 2025 SMART CRC Networking event SMART CRC Australia
2024 - 2024 2024 AWTRS & MBSANZ Scientific Meeting Conference Australian Wound and Tissue Repair Society Australia
2023 - 2023 AWTRS Industry Symposium 2023 Symposium Australian Wound and Tissue Repair Society Australia
2022 - 2022 AWTRS Conference Conference Australian Wound and Tissue Repair Society Australia

Date Engagement Type Partner Name
2023 - ongoing Collaboration Tissue Repair Ltd
2023 - 2023 Collaboration Marinova
2019 - 2023 Collaboration Carina Biotech
2018 - 2018 Collaboration Tekcyte
2018 - 2018 Collaboration Cynata
2015 - 2018 Collaboration Athersys
2015 - 2018 Collaboration Regenesys

Date Topic Presented at Institution Country
2025 - 2025 Biomarkers for diabetic healing SAHMRI Centre South Australian Health and Medical Research Institute Australia
2024 - 2024 The effects of beta glucan on inflammation and the wound healing response 2024 AWTRS & MBSANZ Scientific Meeting Australian Wound and Tissue Repair Society Australia
2023 - 2023 Biomarkers for diabetic healing Adelaide Conference Centre Australian Centre for Accelerating Diabetic Innobvations Australia
2022 - 2022 The role of TLRs during inflammation and the wound healing process Online AWTRS Australia

Date Title Type Institution Country
2025 - 2025 Florey Conference Conference Review University of Adelaide Australia
2025 - 2025 Diabetes Australia Grant Assessment Australian Diabetes Society Australia
2025 - 2025 Assessor of Honors thesis Thesis Review University of Adelaide Australia
2024 - 2024 MRFF Stem Cell Therapies Mission Grant Assessment National Health and Medical Research Council Australia
2023 - 2023 Dutch burns Foundation Grant Assessment Dutch Burns Association Netherlands
2021 - 2021 MRFF Stem Cell Therapies Mission Grant Assessment National Health and Medical Research Council Australia