Prof Michael Roberts

School of Pharmacy and Biomedical Science

College of Health

Eligible to supervise Masters and PhD - email supervisor to discuss availability.


Mike Roberts has a particular interest in therapeutics and pharmaceutical sciences with current studies in critical care medicine, hepatology, quality use of medicines in the community, nanotoxicology, topical delivery, renal impairment after pesticide poisoning, nicotine addiction, pharmacokinetics, drug devlopment and cosmetology. He is probably best known internationally for his work on the absorption of chemicals, cosmetics and drugs through the skin. He has been a full professor for 25 years being initially Professor and Head of Pharmacy at the University of Otago, New Zealand and now as a Senior Principal Research Fellow of the Australian National Health and Medical Research Council. He is jointly appointed as the Chair In Therapeutics and Pharmaceutical Science in the University of South Australia and as the Professor of Clinical Pharmacology and Therapeutics at the University of Queensland. He is also visiting Professeur at the University of Lyon, France and is Director of the Therapeutics Research Centre ( 30 staff and students), based jointly at the Queen Elizabeth Hospital in Adelaide and at and Princess Alexandria Hospital in Brisbane. Mike also co-chairs The Therapeutics and Pharmaceutical Science Consortium in UniSA’s Sansom Institute and leads the inaugural SA government-UniSA pharmacy practitioner program.
His research journey began with an undergraduate project studying solute chemical structure-plastic container sorption relationships in the Reid Building, where his office is now located at UniSA. The resulting studies on drugs uptake by plastic containers and infusion systems are widely referred to in journal reviews, pharmacy references and text books and resulted in forms of their recommended polyolefin infusion systems being widely marketed.
His PhD was on structure penetration and toxicity relationships for phenolic compounds in human skin. This work is now included as core data in pharmaceutical and toxicological data bases (eg US Environmental Protection Agency). He has served/serves on reference committees for WHO, Europe, Health Canada and Australia and presented to regulatory forums in the US.
Mike’s RCTs in the community led, in part, to the Australian government national implementation of medication management for nursing homes and hostels (also now an accreditation requirement), and home medicine reviews by accredited pharmacists. Most recently, he has facilitated the use of imaging and microdialysis techniques to study pharmacokinetics in man in vitro and in vivo, including in critical care and cancer medicine.

I have undertaken and published peer reviewed research across a range of disciplines including: rational drug design, drug delivery (especially skin and oral), clinical pharmacokinetics, the pharmacist’s role in quality use of medicines and translation of research into practice/commercial outcomes. An overarching theme has been a mechanistic understanding of solute structure – delivery system physiological pharmacokinetic relationships and their clinical application.My predominant focus, has, however, been the skin and its interaction with chemicals, formulations and associated technologies. In recent years, I have had a keen interest in how to measure these interactions better and have embraced the use of non-invasive, high resolution, multimodal microscope and spectroscopy technologies to look at what happens inside the skin.I have 40 years research experience (as a tutor, lecturer, full tenured professor; and a NHMRC Senior Principal Research Fellow) across several disciplines but with a focus on the skin and related technologies, and on research seeking to improve patient outcomes. I actively work with industry, government, academia and clinicians, locally and internationally, and talk to specialist groups, e.g. nanotechnology, optics, US Food and Drug Administration.

Year Citation
2025 Roberts, J. A., Ulldemolins, M., Liu, X., Baptista, J. P., Bilgrami, I., Boidin, C., . . . SMARRT Study Collaborators. (2025). Meropenem and piperacillin/tazobactam optimised dosing regimens for critically ill patients receiving renal replacement therapy. Intensive Care Medicine, 51(9), 1628-1640.
DOI Scopus4 WoS4 Europe PMC3
2025 Ionmhain, U. N., Chiew, A. L., Tierney, M., Al Ahmad, J., Pidcock, S., Whan, F. T., . . . Roberts, D. M. (2025). Loperamide-induced severe cardiotoxicity: a toxicokinetic and toxicodynamic analysis derived from a case series and the published literature. Clinical Toxicology, 63(4), 226-235.
DOI
2025 Shihana, F., Wijerathna, T. M., Gawarammana, I. B., Shahmy, S., Chathuranga, U., Palangasinghe, C., . . . Mohamed, F. (2025). Nephrotoxicity biomarkers following propanil (3,4-dichloropropionanilide) self-poisoning. Clinical Toxicology, 63(4), 236-245.
DOI
2025 Roberts, M. S., Zhang, Q., Mackenzie, L., & Medley, G. A. (2025). Quantitative structure permeability relationships for phenolic compounds applied to human epidermal membranes in various solvents. European Journal of Pharmaceutical Sciences, 204(106914), 1-13.
DOI
2024 Qiang, S., Mohamed, F., Raubenheimer, J., Buckley, N. A., Roberts, M. S., & Mackenzie, L. (2024). Clinical toxicology of acute glyphosate self-poisoning: impact of plasma concentrations of glyphosate, its metabolite and polyethoxylated tallow amine surfactants on the toxicity. Clinical Toxicology, 62(8), 483-496.
DOI WoS1 Europe PMC1
2024 Mangion, S. E., Mikkonen, A., Mackenzie, L., Roberts, M. S., & Maibach, H. I. (2024). Multiple topical product dermatitis: paradigms in understanding and future perspectives. JEADV Clinical Practice, 3(1), 49-64.
DOI WoS1
2024 Jia, W., Chandra, J., Teoh, S. M., Tolley, L., Yang, H., Tse, B. W. C., . . . Yu, M. (2024). STING nanoagonist boosts antitumor immunity of therapeutic DNA vaccines. Nano Letters, 24(49), 15588-15597.
DOI Scopus1 WoS1 Europe PMC1
2024 Walsham, J., Hammond, N., Blumenthal, A., Cohen, J., Myburgh, J., Finfer, S., . . . Venkatesh, B. (2024). Fludrocortisone dose-response relationship in septic shock: a randomised phase II trial. Intensive Care Medicine, 50(12), 2050-2060.
DOI Scopus13 WoS13 Europe PMC9
2024 Mohammed, Y. H., Namjoshi, S. N., Jung, N., Windbergs, M., Benson, H. A. E., Grice, J. E., . . . Roberts, M. S. (2024). Topical semisolid drug product critical quality attributes with relevance to cutaneous bioavailability and pharmacokinetics: part I-bioequivalence of acyclovir topical creams. Pharmaceutical Research, 41(7), 1507-1520.
DOI
2024 Mohammed, Y. H., Namjoshi, S. N., Telaprolu, K. C., Jung, N., Shewan, H. M., Stokes, J. R., . . . Roberts, M. S. (2024). Impact of different packaging configurations on a topical cream product. Pharmaceutical Research, 41(10), 2043-2056.
DOI
2024 Namjoshi, S. N., Telaprolu, K. C., Grice, J. E., Benson, H. A. E., Raney, S. G., Roberts, M. S., & Mohammed, Y. H. (2024). Effect of 'in use' administration on topical product metamorphosis and skin permeation of Acyclovir creams: implications for Bioequivalence. Pharmaceutical Research, 41(12), 2391-2401.
DOI
2024 Isoardi, K. Z., Chiew, A. L., Do, C., Humphreys, M., Mustafa, A., Roberts, M. S., & Isbister, G. K. (2024). A prospective study of acute propranolol overdose defining dose thresholds of severe toxicity (ATOM-9). Clinical Toxicology, 63(1), 1-9.
DOI
2023 Zhang, Q., Alinaghi, A., Williams, D. B., & Roberts, M. S. (2023). A thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: II. maximum flux and solute diffusion through stratum corneum lipids. International Journal of Pharmaceutics, 631(122522), 1-11.
DOI WoS2 Europe PMC1
2023 Telaprolu, K. C., Grice, J. E., Mohammed, Y. H., & Roberts, M. S. (2023). Human skin drug metabolism: relationships between methyl salicylate metabolism and esterase activities in IVPT skin membranes. Metabolites, 13(8), 1-12.
DOI
2023 Forouz, F., Mohammed, Y., Nejad, H. S. A. S., Roberts, M. S., & Grice, J. E. (2023). In vitro screening of topical formulation excipients for epithelial toxicity in cancerous and non-cancerous cell lines. EXCLI Journal, 22, 1173-1199.
DOI
2023 Mikkonen, A. T., Martin, J., Upton, R. N., Barker, A. O., Brumley, C. M., Taylor, M. P., . . . Roberts, M. S. (2023). Spatio-temporal trends in livestock exposure to per- and polyfluoroalkyl substances (PFAS) inform risk assessment and management measures. Environmental Research, 225(article no. 115518), 14 pages.
DOI Scopus21 WoS22 Europe PMC15
2023 Mikkonen, A. T., Martin, J., Upton, R. N., Moenning, J. L., Numata, J., Taylor, M. P., . . . Mackenzie, L. (2023). Dynamic exposure and body burden models for per- and polyfluoroalkyl substances (PFAS) enable management of food safety risks in cattle. Environment International, 180(108218), 12 pages.
DOI Scopus13 WoS12 Europe PMC8
2023 Mangion, S. E., Mackenzie, L., Roberts, M. S., & Holmes, A. M. (2023). Seborrheic dermatitis: topical therapeutics and formulation design. European Journal of Pharmaceutics and Biopharmaceutics, 185, 148-164.
DOI WoS16 Europe PMC14
2022 Qiang, S., Mohamed, F., Mackenzie, L., & Roberts, M. S. (2022). Rapid determination of polyethoxylated tallow amine surfactants in human plasma by LC-MSMS. Talanta, 254(124115), 1-12.
DOI WoS6 Europe PMC6
2022 Alinaghi, A., Zhang, Q., Williams, D. B., Mackenzie, L., & Roberts, M. S. (2022). Thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: I. Stratum corneum solubility and partitioning. International Journal Of Pharmaceutics, 630(122424), 1-10.
DOI WoS3 Europe PMC2
2022 Rambabu, L., Mohamed, F., Dhanarisi, J., Gawarammana, I., Raubenheimer, J., Mackenzie, L., . . . Eddleston, M. (2022). Acute phenthoate self-poisoning: a prospective case series. Clinical Toxicology, 60(2), 214-220.
DOI WoS3 Europe PMC1
2022 Al Qurain, A. A., Upton, R. N., Tadros, R., Roberts, M. S., & Wiese, M. D. (2022). Population pharmacokinetic model for tramadol and O-desmethyltramadol in older patients. European Journal of Drug Metabolism and Pharmacokinetics, 47(3), 387-402.
DOI Scopus6 WoS6 Europe PMC6
2022 Zou, D., Wu, Z., Yi, X., Hui, Y., Yang, G., Liu, Y., . . . Zhao, C. -X. (2022). Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 120(1), 1-12.
DOI Scopus62 WoS68 Europe PMC49
2022 Hosseini, M., Roberts, M. S., Aboofazeli, R., & Moghimi, H. R. (2022). Measurement of Hansen Solubility Parameters of third-degree burn eschar. Burns, 48(4), 860-871.
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2022 Rowland, M., Roberts, M. S., & Pang, K. S. (2022). In defense of current concepts and applications of clearance in drug development and therapeutics. Drug Metabolism and Disposition, 50(2), 187-190.
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2022 Calcutt, J. J., Roberts, M. S., & Anissimov, Y. G. (2022). Predicting viable skin concentration: modelling the subpapillary plexus. Pharmaceutical Research, 39(4), 783-793.
DOI
2022 Jung, N., Namjoshi, S., Mohammed, Y., Grice, J. E., Benson, H. A. E., Raney, S. G., . . . Windbergs, M. (2022). Application of confocal Raman microscopy for the characterization of topical semisolid formulations and their penetration into human skin ex vivo. Pharmaceutical Research, 39(5), 935-948.
DOI
2022 Mangion, S. E., Sandiford, L., Mohammed, Y., Roberts, M. S., & Holmes, A. M. (2022). Multi-modal imaging to assess the follicular delivery of zinc pyrithione. Pharmaceutics, 14(5, article no. 1076), 1-14.
DOI
2022 Amarah, A. A., Hadgraft, J., Roberts, M. S., & Anissimov, Y. G. (2022). Compartmental modeling of skin absorption and desorption kinetics: Donor solvent evaporation, variable diffusion/partition coefficients, and slow equilibration process within stratum corneum. International Journal Of Pharmaceutics, 623(121902), 1-10.
DOI
2022 Cheruvu, H. S., Liu, X., Grice, J. E., & Roberts, M. S. (2022). An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions. Data in Brief, 42(108242), 1-9.
DOI Scopus10 WoS8 Europe PMC6
2022 Liu, X., Cheruvu, H. S., Anissimov, Y. G., van der Hoek, J., Tsakalozou, E., Ni, Z., . . . Roberts, M. S. (2022). Percutaneous absorption of steroids from finite doses: predicting urinary excretion from in vitro skin permeation testing. International Journal of Pharmaceutics, 625(122095), 2-16.
DOI Scopus2 WoS2 Europe PMC1
2022 Tapfumaneyi, P., Imran, M., Mohammed, Y., & Roberts, M. S. (2022). Recent advances and future prospective of topical and transdermal delivery systems. Frontiers in Drug Delivery, 2(957732), 1-8.
DOI
2022 Alinaghi, A., Macedo, A., Cheruvu, H. S., Holmes, A., & Roberts, M. S. (2022). Human epidermal in vitro permeation test (IVPT) analyses of alcohols and steroids. International Journal Of Pharmaceutics, 627(122114), 1-18.
DOI
2022 Arora, S., Clarke, J., Tsakalozou, E., Ghosh, P., Alam, K., Grice, J. E., . . . Polak, S. (2022). Mechanistic modeling of in vitro skin permeation and extrapolation to in vivo for topically applied metronidazole drug products using a physiologically based pharmacokinetic model. Molecular Pharmaceutics, 19(9), 3139-3152.
DOI
2022 Mohammed, Y., Holmes, A., Kwok, P. C. L., Kumeria, T., Namjoshi, S., Imran, M., . . . Roberts, M. S. (2022). Advances and future perspectives in epithelial drug delivery. Advanced Drug Delivery Reviews, 186(114293), 1-38.
DOI
2021 Dabbaghi, M., Namjoshi, S., Panchal, B., Grice, J. E., Prakash, S., Roberts, M. S., & Mohammed, Y. (2021). Viscoelastic and deformation characteristics of structurally different commercial topical systems. Pharmaceutics, 13(9), 1-11.
DOI
2021 Liu, X., Anissimov, Y. G., Grice, J. E., Cheruvu, H. S., Ghosh, P., Raney, S. G., . . . Roberts, M. S. (2021). Relating transdermal delivery plasma pharmacokinetics with in vitro permeation test (IVPT) findings using diffusion and compartment-in-series models. Journal of Controlled Release, 334, 37-51.
DOI Scopus8 WoS8 Europe PMC6
2021 Isoardi, K. Z., Page, C. B., Roberts, M. S., & Isbister, G. K. (2021). Life-threatening triclopyr poisoning due to diethylene glycol monoethyl ether solvent. Clinical Toxicology, 59(1), 61-64.
DOI
2021 Buckley, N. A., Fahim, M., Raubenheimer, J., Gawarammana, I. B., Eddleston, M., Roberts, M. S., & Dawson, A. H. (2021). Case fatality of agricultural pesticides after self-poisoning in Sri Lanka: a prospective cohort study. The Lancet Global Health, 9(6), 854-862.
DOI
2021 Roberts, M. S., Cheruvu, H. S., Mangion, S. E., Alinaghi, A., Benson, H. A. E., Mohammed, Y., . . . Grice, J. E. (2021). Topical drug delivery: history, percutaneous absorption, and product development. Advanced Drug Delivery Reviews, 177(113929), 1-43.
DOI
2021 Khabir, Z., Holmes, A. M., Lai, Y. J., Liang, L., Deva, A., Polikarpov, M. A., . . . Zvyagin, A. V. (2021). Human epidermal zinc concentrations after topical application of ZnO nanoparticles in sunscreens. International Journal of Molecular Sciences, 22(22, article no. 12372), 1-18.
DOI
2021 Abd, E., Gomes, J., Sales, C. C., Yousef, S., Forouz, F., Telaprolu, K. C., . . . Andréo Filho, N. (2021). Deformable liposomes as enhancer of caffeine penetration through human skin in a Franz diffusion cell test. International Journal of Cosmetic Science, 43(1), 1-10.
DOI
2021 Calcutt, J. J., Roberts, M. S., & Anissimov, Y. G. (2021). Modelling drug transport within the viable skin - a review. Expert Opinion on Drug Metabolism & Toxicology, 17(1), 105-119.
DOI
2021 Roberts, J. A., Joynt, G., Lee, A., Choi, G., Bellomo, R., Kanji, S., . . . Lipman, J. (2021). The effect of renal replacement therapy and antibiotic dose on antibiotic concentrations in critically ill patients: data from the multinational Sampling Antibiotics in Renal Replacement Therapy Study. Clinical Infectious Diseases, 72(8), 1369-1378.
DOI Scopus119 WoS111 Europe PMC95
2021 Al Qurain, A. A., Gebremichael, L. G., Khan, M. S., Williams, D. B., Mackenzie, L., Phillips, C., . . . Wiese, M. D. (2021). Opioid prescribing and risk of drug-opioid interactions in older discharged patients with polypharmacy in Australia. International Journal of Clinical Pharmacy, 43(2), 365-374.
DOI Scopus9 WoS8 Europe PMC9
2021 Al Qurain, A. A., Upton, R., Williams, D. B., Mackenzie, L., Phillips, C., Russell, P. T., . . . Wiese, M. D. (2021). Population pharmacokinetic model of subcutaneous fentanyl in older acute care patients. European Journal Of Clinical Pharmacology, 77(9), 1357-1368.
DOI Scopus3 WoS4 Europe PMC4
2021 Brooks, A., Liang, X., Zhang, Y., Zhao, C. X., Roberts, M. S., Wang, H., . . . Crawford, D. H. G. (2021). Liver organoid as a 3D in vitro model for drug validation and toxicity assessment. Pharmacological Research, 169, 105608-1-105608-8.
DOI Scopus88 WoS83 Europe PMC63
2021 Gebremichael, L. G., Suppiah, V., Wiese, M. D., Mackenzie, L., Phillips, C., Williams, D. B., & Roberts, M. S. (2021). Efficacy and safety of statins in ethnic differences: a lesson for application in Indigenous Australian patient care. Pharmacogenomics, 22(9), 553-571.
DOI Scopus1
2021 Zou, D., Wang, H., Liu, X., Xu, Z. P., Roberts, M. S., & Zhao, C. X. (2021). Artificial cells for the treatment of liver diseases. Acta Biomaterialia, 130, 98-114.
DOI Scopus12 WoS12 Europe PMC7
2021 Al Qurain, A. A., Williams, D. B., Mackenzie, L., Roberts, M. S., & Wiese, M. D. (2021). Simultaneous LC-MS/MS quantification of oxycodone, tramadol and fentanyl and their metabolites (noroxycodone, oxymorphone, O- desmethyltramadol, N- desmethyltramadol, and norfentanyl) in human plasma and whole blood collected via venepuncture and volumetric absorptive micro sampling. Journal of Pharmaceutical and Biomedical Analysis, 203(114171), 1-8.
DOI WoS11 Europe PMC10
2020 Holmes, A. M., Mackenzie, L., & Roberts, M. S. (2020). Disposition and measured toxicity of zinc oxide nanoparticles and zinc ions against keratinocytes in cell culture and viable human epidermis. Nanotoxicology, 14(2), 263-274.
DOI WoS37 Europe PMC19
2020 Holmes, A. M., Kempson, I., Turnbull, T., Paterson, D., & Roberts, M. S. (2020). Penetration of Zinc into Human Skin after Topical Application of Nano Zinc Oxide Used in Commercial Sunscreen Formulations. ACS Applied Bio Materials, 3(6), 3640-3647.
DOI Scopus37 WoS34 Europe PMC19
2020 Ruan, Q., Wang, H., Burke, L. J., Bridle, K. R., Li, X., Zhao, C. X., . . . Liang, X. (2020). Therapeutic modulators of hepatic stellate cells for hepatocellular carcinoma. International Journal of Cancer, 147(6), 1519-1527.
DOI Scopus38 WoS37 Europe PMC31
2020 Al Qurain, A. A., Gebremichael, L. G., Khan, M. S., Williams, D. B., Mackenzie, L., Phillips, C., . . . Wiese, M. D. (2020). Prevalence and factors associated with analgesic prescribing in poly-medicated elderly patients. Drugs and Aging, 37(4), 291-300.
DOI Scopus22 WoS23 Europe PMC19
2020 Forouz, F., Dabbaghi, M., Namjoshi, S., Mohammed, Y., Roberts, M. S., & Grice, J. E. (2020). Development of an oil-in-water self-emulsifying microemulsion for cutaneous delivery of rose Bengal: Investigation of anti-melanoma properties. Pharmaceutics, 12(10), 1-17.
DOI
2020 Ezati, N., Roberts, M. S., Zhang, Q., & Moghimi, H. R. (2020). Measurement of Hansen Solubility Parameters of human stratum corneum. Iranian Journal of Pharmaceutical Research, 19(3), 572-578.
DOI WoS16 Europe PMC12
2020 Cheruvu, H. S., Liu, X., Grice, J. E., & Roberts, M. S. (2020). Modeling percutaneous absorption for successful drug discovery and development. Expert Opinion on Drug Discovery, 15(10), 1181-1198.
DOI Scopus22 WoS18 Europe PMC13
2020 Liu, X., Yousef, S., Anissimov, Y. G., van der Hoek, J., Tsakalozou, E., Ni, Z., . . . Roberts, M. S. (2020). Diffusion modelling of percutaneous absorption kinetics. Predicting urinary excretion from in vitro skin permeation tests (IVPT) for an infinite dose. European Journal of Pharmaceutics and Biopharmaceutics, 149, 30-44.
DOI Scopus10 WoS8 Europe PMC3
2020 Nastiti, C. M. R. R., Ponto, T., Mohammed, Y., Roberts, M. S., & Benson, H. A. E. (2020). Novel nanocarriers for targeted topical skin delivery of the antioxidant resveratrol. Pharmaceutics, 12(2), 1-15.
DOI
2020 Mohammed, Y. H., Haridass, I. N., Grice, J. E., Benson, H. A. E., & Roberts, M. S. (2020). Bathing does not facilitate human skin penetration or adverse cellular effects of nanoparticulate zinc oxide sunscreens after topical application. Journal of Investigative Dermatology, 140(8), 1656-1659.
DOI
2020 Namjoshi, S., Dabbaghi, M., Roberts, M. S., Grice, J. E., & Mohammed, Y. (2020). Quality by design: development of the quality target product profile (QTPP) for semisolid topical products. Pharmaceutics, 12(3), 1-12.
DOI
2020 Barkauskas, D. S., Medley, G., Liang, X., Mohammed, Y. H., Thorling, C. A., Wang, H., & Roberts, M. S. (2020). Using in vivo multiphoton fluorescence lifetime imaging to unravel disease-specific changes in the liver redox state. Methods and Applications in Fluorescence, 8(3), 034003.
DOI Scopus7 Europe PMC5
2020 Mohammed, Y., Barkauskas, D., Holmes, A., Grice, J., & Roberts, M. S. (2020). Noninvasive in vivo human multiphoton microscopy: a key method in proving nanoparticulate zinc oxide sunscreen safety. Journal of Biomedical Optics, 25(1), 1-19.
DOI
2019 Vieira, C. O., Grice, J. E., Roberts, M. S., Haridass, I. N., Duque, M. D., Lopes, P. S., . . . Martins, T. S. (2019). ZnO:SBA-15 nanocomposites for potential use in sunscreen: preparation, properties, human skin penetration and toxicity. Skin pharmacology and physiology, 32(1), 32-42.
DOI
2019 Latter, G., Grice, J. E., Mohammed, Y., Roberts, M. S., & Benson, H. A. E. (2019). Targeted topical delivery of retinoids in the management of acne vulgaris: current formulations and novel delivery systems. Pharmaceutics, 11(10, article no. 490), 1-26.
DOI
2019 Abd, E., Benson, H. A. E., Mohammed, Y. H., Roberts, M. S., & Grice, J. E. (2019). Permeation mechanism of caffeine and naproxen through in vitro human epidermis: effect of vehicles and penetration enhancers. Skin pharmacology and physiology, 32(3), 132-141.
DOI
2019 Sandiford, L., Holmes, A. M., Mangion, S. E., Mohammed, Y. H., Zvyagin, A. V., & Roberts, M. S. (2019). Optical characterization of zinc pyrithione. Photochemistry and photobiology, 95(5), 1142-1150.
DOI
2019 Benson, H. A. E., Grice, J. E., Mohammed, Y., Namjoshi, S., & Roberts, M. S. (2019). Topical and transdermal drug delivery: from simple potions to smart technologies. Current drug delivery, 16(5), 444-460.
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2019 Nastiti, C. M. R. R., Mohammed, Y., Telaprolu, K. C., Liang, X., Grice, J. E., Roberts, M. S., & Benson, H. A. E. (2019). Evaluation of quantum dot skin penetration in porcine skin: effect of age and anatomical site of topical application. Skin pharmacology and physiology, 32(4), 182-191.
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2019 Haridass, I. N., Wei, J. C. J., Mohammed, Y. H., Crichton, M. L., Anderson, C. D., Henricson, J., . . . Roberts, M. S. (2019). Cellular metabolism and pore lifetime of human skin following microprojection array mediation. Journal of controlled release, 306, 59-68.
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2019 Schultz, H. B., Vasani, R. B., Holmes, A. M., Roberts, M. S., & Voelcker, N. H. (2019). Stimulus-responsive antibiotic releasing systems for the treatment of wound infections. ACS applied bio materials, 2(2), 704-716.
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2019 Yousef, S. A., Mohammed, Y. H., Namjoshi, S., Grice, J. E., Benson, H. A. E., Sakran, W., & Roberts, M. S. (2019). Mechanistic evaluation of enhanced curcumin delivery through human skin in vitro from optimised nanoemulsion formulations fabricated with different penetration enhancers. Pharmaceutics, 11(12, article no. 639), 1-20.
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2019 Mohammed, Y. H., Holmes, A., Haridass, I. N., Sanchez, W. Y., Studier, H., Grice, J. E., . . . Roberts, M. S. (2019). Support for the safe use of zinc oxide nanoparticle sunscreens: lack of skin penetration or cellular toxicity after repeated application in volunteers. The journal of investigative dermatology, 139(2), 308-315.
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2019 Rainsford, K. D., Roberts, M. S., Nencioni, A., & Jones, C. (2019). Rationale and evidence for the incorporation of heparin into the diclofenac epolamine medicated plaster. Current Medical Research and Opinion, 35(6), 989-1002.
DOI Scopus2 WoS1
2019 Abraham, J., Sinnollareddy, M. G., Roberts, M. S., Williams, P., Peake, S. L., Lipman, J., & Roberts, J. A. (2019). Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsis. International Journal of Antimicrobial Agents, 53(2), 137-142.
DOI Scopus17 WoS17 Europe PMC13
2019 Wang, H., Lu, H., Yang, H., Zhang, X., Thompson, E. W., Roberts, M. S., . . . Li, X. (2019). Impact of Age on Risk of Lymph Node Positivity in Patients with Colon Cancer. Journal of cancer, 10(9), 2102-2108.
DOI Scopus8 Europe PMC9
2019 Xiao, W., Green, T. I. P., Liang, X., Delint, R. C., Perry, G., Roberts, M. S., . . . Perriman, A. W. (2019). Designer artificial membrane binding proteins to direct stem cells to the myocardium. Chemical science, 10(32), 7610-7618.
DOI Scopus15 Europe PMC10
2018 Jin, W., Liang, X., Brooks, A., Futrega, K., Liu, X., Doran, M. R., . . . Wang, H. (2018). Modelling of the SDF-1/CXCR4 regulated in vivo homing of therapeutic mesenchymal stem/stromal cells in mice. PeerJ, 2018(12, article no. e6072), 1-17.
DOI Scopus62 WoS60 Europe PMC47
2018 Wang, H., Yang, H., Xu, Z. P., Liu, X., Roberts, M. S., & Liang, X. (2018). Anionic long-circulating quantum dots for long-term intravital vascular imaging. Pharmaceutics, 10(4, article no. 244), 1-8.
DOI Scopus13 WoS10 Europe PMC11
2018 Yamada, M., Tayeb, H., Wang, H., Dang, N., Mohammed, Y. H., Osseiran, S., . . . Prow, T. W. (2018). Using elongated microparticles to enhance tailorable nanoemulsion delivery in excised human skin and volunteers. Journal of controlled release, 288, 264-276.
DOI Scopus27 Europe PMC14
2018 Andréo Filho, N., Bim, A. V. K., Kaneko, T. M., Kitice, N. A., Haridass, I. N., Abd, E., . . . Leite Silva, V. R. (2018). Development and evaluation of lipid nanoparticles containing natural botanical oil for sun protection: characterization and in vitro and in vivo human skin permeation and toxicity. Skin pharmacology and physiology, 31(1), 1-9.
DOI Scopus35 Europe PMC14
2018 Brooks, A., Futrega, K., Liang, X., Hu, X., Liu, X., Crawford, D. H. G., . . . Wang, H. (2018). Concise review: quantitative detection and modeling the in vivo kinetics of therapeutic mesenchymal stem/stromal cells. Stem cells translational medicine, 7(1), 78-86.
DOI Scopus46 WoS41 Europe PMC36
2018 Sinnollareddy, M. G., Roberts, M. S., Lipman, J., Peake, S. L., & Roberts, J. A. (2018). Pharmacokinetics of piperacillin in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration. Journal of antimicrobial chemotherapy, 73(6), 1647-1650.
DOI Scopus19 WoS19 Europe PMC16
2018 Wang, H., Li, X., Tse, B. W. C., Yang, H., Thorling, C. A., Liu, Y., . . . Liang, X. (2018). Indocyanine green-incorporating nanoparticles for cancer theranostics. Theranostics, 8(5), 1227-1242.
DOI Scopus324 WoS307 Europe PMC216
2018 Warren, S. C., Nobis, M., Magenau, A., Mohammed, Y. H., Herrmann, D., Moran, I., . . . Timpson, P. (2018). Removing physiological motion from intravital and clinical functional imaging data. Elife, 7, 1-37.
DOI Scopus41 Europe PMC28
2018 Holmes, A. M., Kempson, I., Turnbull, T., Paterson, D., & Roberts, M. S. (2018). Imaging the penetration and distribution of zinc and zinc species after topical application of zinc pyrithione to human skin. Toxicology and Applied Pharmacology, 343, 40-47.
DOI Scopus23 WoS19 Europe PMC13
2018 Wei, J. C. J., Haridass, I. N., Crichton, M. L., Mohammed, Y. H., Meliga, S. C., Sanchez, W. Y., . . . Kendall, M. A. F. (2018). Space-and time-resolved investigation on diffusion kinetics of human skin following macromolecule delivery by microneedle arrays. Scientific reports, 8(17759), 1-15.
DOI
2018 Rzhevskiy, A. S., Telaprolu, K., Mohammed, Y. H., Grice, J. E., Roberts, M. S., & Anissimov, Y. G. (2018). Using a simple equation to predict the microporation-enhanced transdermal drug flux. European journal of pharmaceutics and biopharmaceutics, 127, 12-18.
DOI
2018 Chan, B. S. H., Chiew, A. L., Grainger, S., Page, C. B., Gault, A., Mostafa, A., . . . Isbister, G. K. (2018). Bromoxynil and 2-methyl-4-chlorophenoxyacetic acid (MCPA) poisoning could be a bad combination. Clinical toxicology, 56(9), 861-863.
DOI Scopus5 WoS4 Europe PMC4
2018 Abd, E., Benson, H. A. E., Roberts, M. S., & Grice, J. E. (2018). Minoxidil skin delivery from nanoemulsion formulations containing eucalyptol or oleic acid: enhanced diffusivity and follicular targeting. Pharmaceutics, 10(1, article no.19), 1-12.
DOI
2018 Le, T., Gong, Y., Wang, G., Davies, N. M., Lillico, R., Lakowski, T., . . . Burczynski, F. J. (2018). The antioxidant activity of recombinant rat hepatic fatty acid binding protein t94a variant. Journal of pharmacy and pharmaceutical sciences, 21(1s), 309s-324s.
DOI Scopus2 Europe PMC2
2018 Junqueira Garcia, M. T., de Vasconcellos, F. L. L., Raffier, C. P., Roberts, M. S., Grice, J. E., Benson, H. A. E., & Leite Silva, V. R. (2018). Alternative methods to animal studies for the evaluation of topical/transdermal drug delivery systems. Current topics in medicinal chemistry, 18(4), 287-299.
DOI
2018 Abd, E., Benson, H. A. E., Roberts, M. S., & Grice, J. E. (2018). Follicular penetration of caffeine from topically applied nanoemulsion formulations containing penetration enhancers: in vitro human skin studies. Skin pharmacology and physiology, 31(5), 252-260.
DOI
2018 Morley, K. C., Baillie, A., Fraser, I., Furneaux Bate, A., Dore, G., Roberts, M., . . . Haber, P. S. (2018). Baclofen in the treatment of alcohol dependence with or without liver disease: multisite, randomised, double-blind, placebo-controlled trial. British journal of psychiatry, 212(6), 362-369.
DOI
2018 Amarah, A. A., Petlin, D. G., Grice, J. E., Hadgraft, J., Roberts, M. S., & Anissimov, Y. G. (2018). Compartmental modeling of skin transport. European journal of pharmaceutics and biopharmaceutics, 130, 336-344.
DOI
2018 Chiew, A. L., Wright, D. F. B., Dobos, N. M., McArdle, K., Mostafa, A. A., Newth, A., . . . Isbister, G. K. (2018). 'Massive' metformin overdose. British journal of clinical pharmacology, 84(12), 2923-2927.
DOI Scopus19 Europe PMC18
2018 Khan, M. S., & Roberts, M. S. (2018). Challenges and innovations of drug delivery in older age. Advanced drug delivery reviews, 135, 3-38.
DOI Scopus65 WoS55 Europe PMC31
2018 Chan, B. S., Becker, T., Chiew, A. L., Abdalla, A. M., Robertson, T. A., Liu, X., . . . Buckley, N. A. (2018). Vasoplegic shock treated with methylene blue complicated by severe serotonin syndrome. Journal of medical toxicology, 14(1), 1-4.
DOI Scopus14 WoS15 Europe PMC12
2018 Chiew, A. L., Page, C. B., Clancy, D., Mostafa, A., Roberts, M. S., & Isbister, G. K. (2018). 2-Methyl-4-chlorophenoxyacetic acid (MCPA) and bromoxynil herbicide ingestion. Clinical toxicology, 56(5), 377-380.
DOI
2018 Alahakoon, C., Dassanayake, T. L., Gawarammana, I. B., Sedgwick, E. M., Weerasinghe, V. S., Abdalla, A., . . . Buckley, N. A. (2018). Prediction of organophosphorus insecticide-induced intermediate syndrome with stimulated concentric needle single fibre electromyography. PLoS one, 13(9), 1-19.
DOI
2018 Chiew, A. L., Wright, D. F. B., Roberts, M. S., & Isbister, G. K. (2018). Response to ‘Comment on ‘‘Massive’ metformin overdose’ by Chiew et al.’. British Journal of Clinical Pharmacology, 84(12), 2940-2941.
DOI Scopus1 Europe PMC2
2017 Wong, L. Y., Wong, A., Robertson, T., Burns, K., Roberts, M., & Isbister, G. K. (2017). Severe hypertension and bradycardia secondary to midodrine overdose. Journal of medical toxicology, 13(1), 88-90.
DOI
2017 Nastiti, C. M. R. R., Ponto, T., Abd, E., Grice, J. E., Benson, H. A. E., & Roberts, M. S. (2017). Topical nano and microemulsions for skin delivery. Pharmaceutics, 9(4, article no. 37), 1-25.
DOI
2017 Gilbert, A. V., Patel, B. K., Roberts, M. S., Williams, D. B., Crofton, J. H., Morris, N. M., . . . Gilbert, A. L. (2017). An audit of medicines information quality in electronically generated discharge summaries: evidence to meet the Australian national safety and quality health service standards. Journal of pharmacy practice and research, 47(5), 355-364.
DOI
2017 Berling, I., Mostafa, A., Grice, J. E., Roberts, M. S., & Isbister, G. K. (2017). Warfarin poisoning with delayed rebound toxicity. Journal of emergency medicine, 52(2), 194-196.
DOI
2017 Roberts, M. S., Mohammed, Y., Pastore, M. N., Namjoshi, S., Yousef, S., Alinaghi, A., . . . Grice, J. E. (2017). Topical and cutaneous delivery using nanosystems. Journal of controlled release, 247, 86-105.
DOI
2017 Cardon Dunbar, A., Robertson, T., Roberts, M. S., & Isbister, G. K. (2017). Pramipexole overdose associated with visual hallucinations, agitation and myoclonus. Journal of medical toxicology, 13(4), 343-346.
DOI
2017 Yousef, S., Mohammed, Y., Namjoshi, S., Grice, J., Sakran, W., & Roberts, M. (2017). Mechanistic evaluation of hydration effects on the human epidermal permeation of salicylate esters. AAPS journal, 19(1), 180-190.
DOI
2017 Wang, H., Thorling, C. A., Xu, Z. P., Crawford, D. H. G., Liang, X., Liu, X., & Roberts, M. S. (2017). Visualization and modeling of the In vivo distribution of mesenchymal stem cells. Current protocols in stem cell biology, 43(1), 2B.8.1-2B.8.17.
DOI Scopus3 Europe PMC2
2017 Sime, F., Hahn, U., Warner, M., Tiong, I., Roberts, M., Lipman, J., . . . Robertsa, J. (2017). Using population pharmacokinetic modeling and Monte Carlo simulations to determine whether standard doses of piperacillin in piperacillin-tazobactam regimens are adequate for the management of febrile neutropenia. Antimicrobial Agents and Chemotherapy, 61(11), e00311-17-1-e00311-17-13.
DOI Scopus29 WoS27 Europe PMC24
2017 Wang, H., Liang, X., Gravot, G., Thorling, C. A., Crawford, D. H. G., Xu, Z. P., . . . Roberts, M. S. (2017). Visualizing liver anatomy, physiology and pharmacology using multiphoton microscopy. Journal of biophotonics, 10(1), 46-60.
DOI Scopus39 WoS37 Europe PMC25
2017 Wang, H., Zhang, R., Bridle, K. R., Jayachandran, A., Thomas, J. A., Zhang, W., . . . Roberts, M. S. (2017). Two-photon dual imaging platform for in vivo monitoring cellular oxidative stress in liver injury. Scientific reports, 7(45374), 1-11.
DOI Scopus47 WoS43 Europe PMC24
2017 Jayaweera, D., Islam, S., Gunja, N., Cowie, C., Broska, J., Poojara, L., . . . Isbister, G. K. (2017). Chloroform ingestion causing severe gastrointestinal injury, hepatotoxicity and dermatitis confirmed with plasma chloroform concentrations. Clinical toxicology, 55(2), 147-150.
DOI Scopus18 WoS13 Europe PMC10
2016 Pastore, M., Studier, H., Bonder, C., & Roberts, M. (2016). Non-invasive metabolic imaging of melanoma progression. Experimental Dermatology, 26(7), 1-8.
DOI Scopus40 WoS35 Europe PMC17
2016 Sinnollareddy, M. G., Roberts, M. S., Lipman, J., Lassig-Smith, M., Starr, T., Robertson, T., . . . Roberts, J. A. (2016). In vivo microdialysis to determine subcutaneous interstitial fluid penetration and pharmacokinetics of fluconazole in intensive care unit patients with sepsis. Antimicrobial Agents and Chemotherapy, 60(2), 827-832.
DOI Scopus19 WoS18 Europe PMC13
2016 Roberts, J. A., Choi, G. Y. S., Joynt, G. M., Paul, S. K., Deans, R., Peake, S., . . . Lipman, J. (2016). SaMpling Antibiotics in Renal Replacement Therapy (SMARRT): an observational pharmacokinetic study in critically ill patients. BMC Infectious Diseases, 16(1), 103-1-103-8.
DOI Scopus15 WoS14 Europe PMC10
2016 Wang, H., Liang, X., Xu, Z. P., Crawford, D. H. G., Liu, X., & Roberts, M. (2016). A physiologically based kinetic model for elucidating the in vivo distribution of administered mesenchymal stem cells. Scientific Reports, 6(22293), 1-12.
DOI Scopus32 WoS29 Europe PMC26
2016 Liang, X., Wang, H., Grice, J. E., Li, L., Liu, X., Xu, Z. P., & Roberts, M. S. (2016). Physiologically based pharmacokinetic model for long-circulating inorganic nanoparticles. Nano letters, 16(2), 939-945.
DOI Scopus55 WoS49 Europe PMC42
2016 Liang, X., Wang, H., Zhu, Y., Zhang, R., Cogger, V. C., Liu, X., . . . Roberts, M. S. (2016). Short-and long-term tracking of anionic ultrasmall nanoparticles in kidney. ACS nano, 10(1), 387-395.
DOI Scopus116 WoS110 Europe PMC77
2016 Holmes, A. M., Lim, J., Studier, H., & Roberts, M. S. (2016). Varying the morphology of silver nanoparticles results in differential toxicity against micro-organisms, HaCaT keratinocytes and affects skin deposition. Nanotoxicology, 10(10), 1503-1514.
DOI Scopus43 WoS41 Europe PMC31
2016 Abd, E., Yousef, S. A., Pastore, M. N., Telaprolu, K., Mohammed, Y., Namjoshi, S., . . . Roberts, M. (2016). Skin models for the testing of transdermal drugs. Clinical pharmacology: advances and applications, 8, 163-176.
DOI
2016 Alobaid, A. S., Wallis, S. C., Jarrett, P., Starr, T., Stuart, J., Lassig Smith, M., . . . Roberts, J. A. (2016). Effect of obesity on the population pharmacokinetics of fluconazole in critically Ill patients. Antimicrobial agents and chemotherapy, 60(12), 6550-6557.
DOI Europe PMC33
2016 Leite Silva, V. R., Sanchez, W. Y., Studier, H., Liu, D. C., Mohammed, Y. H., Holmes, A. M., . . . Roberts, M. S. (2016). Human skin penetration and local effects of topical nano zinc oxide after occlusion and barrier impairment. European Journal of Pharmaceutics and Biopharmaceutics, 104, 140-147.
DOI Scopus62 WoS55 Europe PMC37
2016 Alobaid, A. S., Brinkmann, A., Frey, O. R., Roehr, A. C., Luque, S., Grau, S., . . . Roberts, J. A. (2016). What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?. Journal of antimicrobial chemotherapy, 71(3), 696-702.
DOI
2016 Yousef, S., Liu, X., Mostafa, A., Mohammed, Y., Grice, J. E., Anissimov, Y. G., . . . Roberts, M. S. (2016). Estimating maximal In vitro skin permeation flux from studies using non-sink receptor phase conditions. Pharmaceutical research, 33(9), 2180-2194.
DOI Scopus21 WoS20 Europe PMC12
2016 Abd, E., Namjoshi, S., Mohammed, Y. H., Roberts, M. S., & Grice, J. E. (2016). Synergistic skin penetration enhancer and nanoemulsion formulations promote the human epidermal permeation of caffeine and naproxen. Journal of pharmaceutical sciences, 105(1), 212-220.
DOI
2016 Holmes, A. M., Song, Z., Moghimi, H. R., & Roberts, M. (2016). Relative penetration of zinc oxide and zinc ions into human skin after application of different zinc oxide formulations. ACS nano, 10(2), 1810-1819.
DOI Scopus108 WoS96 Europe PMC57
2016 Abd, E., Roberts, M. S., & Grice, J. E. (2016). A comparison of the penetration and permeation of caffeine into and through human epidermis after application in various vesicle formulations. Skin pharmacology and physiology, 29(1), 24-30.
DOI
2016 Page, C. B., Mostafa, A., Saiao, A., Grice, J. E., Roberts, M. S., & Isbister, G. K. (2016). Cardiovascular toxicity with levetiracetam overdose. Clinical Toxicology, 54(2), 152-154.
DOI
2016 Leite Silva, V. R., Liu, D. C., Sanchez, W. Y., Studier, H., Mohammed, Y. H., Holmes, A., . . . Roberts, M. S. (2016). Effect of flexing and massage on in vivo human skin penetration and toxicity of zinc oxide nanoparticles. Nanomedicine, 11(10), 1193-1205.
DOI Scopus54 Europe PMC31
2016 Chandrasekaran, N. C., Sanchez, W. Y., Mohammed, Y. H., Grice, J. E., Roberts, M. S., & Barnard, R. T. (2016). Permeation of topically applied Magnesium ions through human skin is facilitated by hair follicles. Magnesium research, 29(2), 35-42.
DOI
2016 Lamb, T., Selvarajah, L. R., Mohamed, F., Jayamanne, S., Gawarammana, I., Mostafa, A., . . . Eddleston, M. (2016). High lethality and minimal variation after acute self-poisoning with carbamate insecticides in Sri Lanka: implications for global suicide prevention. Clinical toxicology, 54(8), 624-631.
DOI
2016 Isbister, G. K., Ang, K., Gorman, K., Cooper, J., Mostafa, A., & Roberts, M. S. (2016). Zero-order metoprolol pharmacokinetics after therapeutic doses: severe toxicity and cardiogenic shock. Clinical toxicology, 54(9), 881-885.
DOI
2015 Berling, I., Buckley, N. A., Mostafa, A., Downes, M. A., Grice, J., Medley, G., . . . Isbister, G. K. (2015). 2-Methyl-4-chlorophenoxyacetic acid and bromoxynil herbicide death. Clinical Toxicology, 53(5), 486-488.
DOI
2015 Gordon, S., Daneshian, M., Bouwstra, J., Caloni, F., Roberts, M. S., & Lehr, C. M. (2015). Non-animal models of epithelial barriers (skin, intestine and lung) in research, industrial applications and regulatory toxicology. Altex, 32(4), 327-378.
DOI Scopus129 WoS108 Europe PMC75
2015 Sime, F. B. R., Roberts, M. S., & Roberts, J. (2015). Optimization of dosing regimens and dosing in special populations. Clinical Microbiology and Infection, 21(10), 886-893.
DOI
2015 Skinner, K., Saiao, A., Mostafa, A., Soderstrom, J., Medley, G., Roberts, M. S., & Isbister, G. K. (2015). Isoniazid poisoning: pharmacokinetics and effect of hemodialysis in a massive ingestion. Hemodialysis international, 19(4), 37-40.
DOI
2015 Downes, M. A., Berling, I. L., Mostafa, A., Grice, J., Roberts, M. S., & Isbister, G. K. (2015). Acute behavioural disturbance associated with phenibut purchased via an internet supplier. Clinical toxicology, 53(7), 636-638.
DOI
2015 Mahmood, A. H., Liu, X., Grice, J. E., Medley, G. A., & Roberts, M. S. (2015). Using deconvolution to understand the mechanism for variable plasma concentration-time profiles after intramuscular injection. International journal of pharmaceutics, 481(1-2), 71-78.
DOI Scopus6 WoS6 Europe PMC5
2015 Wang, H., Thorling, C. A., Liang, X., Bridle, K. R., Grice, J. E., Zhu, Y., . . . Roberts, M. S. (2015). Diagnostic imaging and therapeutic application of nanoparticles targeting the liver. Journal of materials chemistry B, 3(6), 939-958.
DOI Scopus152 WoS135
2015 Michael, A. P., Mostafa, A., Cooper, J., Grice, J., Roberts, M. S., & Isbister, G. K. (2015). The pharmacokinetics and pharmacodynamics of severe aldicarb toxicity after overdose. Clinical toxicology, 53(7), 633-635.
DOI Scopus4 Europe PMC3
2015 Pastore, M. N., Kalia, Y. N., Horstmann, M., & Roberts, M. S. (2015). Transdermal patches: history, development and pharmacology. British journal of pharmacology, 172(9), 2179-2209.
DOI
2015 Thorling, C. A., Jin, L., Weiss, M., Crawford, D., Liu, X., Burczynski, F. J., . . . Roberts, M. S. (2015). Assessing steatotic liver function after ischemia-reperfusion injury by in vivo multiphoton imaging of fluorescein disposition. Drug metabolism and disposition, 43(1), 154-162.
DOI Scopus21 WoS21 Europe PMC9
2015 Roberts, J. A., Udy, A. A., Jarrett, P., Wallis, S. C., Hope, W. W., Sharma, R., . . . Lipman, J. (2015). Plasma and target-site subcutaneous tissue population pharmacokinetics and dosing simulations of cefazolin in post-traumacritically ill patients. Journal of antimicrobial chemotherapy, 70(5), 1495-1502.
DOI Scopus63 Europe PMC57
2015 Udy, A. A., Lipman, J., Jarrett, P., Klein, K., Wallis, S. C., Patel, K., . . . Roberts, J. A. (2015). Are standard doses of piperacillin sufficient for critically ill patients with augmented creatinine clearance?. Critical care, 19(1, article no. 28), 1-9.
DOI Scopus127 WoS116 Europe PMC102
2015 Liang, X. L., Grice, J. E., Zhu, Y., Liu, D., Sanchez, W. Y., Li, Z., . . . Roberts, M. S. (2015). Intravital multiphoton imaging of the selective uptake of water-dispersible quantum dots into sunusoidal liver cells. Small, 11(14), 1711-1720.
DOI Scopus37 WoS38 Europe PMC29
2015 Sinnollareddya, M. G., Roberts, M. S., Lipman, J., Robertson, T. A., Peake, S. L., & Roberts, J. A. (2015). Pharmacokinetics of fluconazole in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration. International Journal of Antimicrobial Agents, 45(2), 192-195.
DOI Scopus12 WoS12 Europe PMC6
2015 Reeve, E., Andrews, J., Wiese, M., Hendrix, I., Roberts, M., & Shakib, S. (2015). Feasibility of a patient-centered deprescribing process to reduce inappropriate use of proton pump inhibitors. Annals of Pharmacotherapy, 49(1), 29-38.
DOI Scopus76 WoS58 Europe PMC54
2015 Wang, H., Liang, X., Mohammed, Y. H., Thomas, J. A., Bridle, K. R., Thorling, C. A., . . . Roberts, M. S. (2015). Real-time histology in liver disease usingmultiphoton microscopy with fluorescencelifetime imaging. Biomedical Optics Express, 9(3), 780-792.
DOI Scopus53 WoS49 Europe PMC31
2015 Sinnollareddy, M., Roberts, M., Lipman, J., Peake, S., & Roberts, J. (2015). Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: use of microdialysis. International Journal of Antimicrobial Agents, 46(1), 121-124.
DOI Scopus6 WoS6 Europe PMC5
2015 Sime, F. B., Roberts, M. S., Tiong, I. S., Gardner, J. H., Lehman, S., Peake, S. L., . . . Roberts, J. A. (2015). Can therapeutic drug monitoring optimize exposure to piperacillin in febrile neutropenic patients with haematological malignancies? A randomized controlled trial. Journal of Antimicrobial Chemotherapy, 70(8), 2369-2375.
DOI Scopus75 WoS68 Europe PMC57
2015 Roberts, D. M., Xin, L., Roberts, J. A., Nair, P., Cole, L., Roberts, M., . . . Bellomo, R. (2015). A multicenter study on the effect of continuous hemodiafiltration intensity on antibiotic pharmacokinetics. Critical Care, 19(1), 1-9.
DOI Scopus121 WoS115 Europe PMC99
2015 Arab, H. A., Walker, N. I., Cheung, K., Hickman, P. E., Potter, J. M., Kadkhodaee, M., & Roberts, M. S. (2015). Free radical scavengers improve liver function but not morphological changes induced by reperfusion injury. Journal of investigative surgery, 28(2), 77-85.
DOI WoS1 Europe PMC1
2015 Sime, F. B., Roberts, M. S., Tiong, I. S., Gardner, J. H., Lehman, S., Peake, S. L., . . . Roberts, J. A. (2015). Adequacy of high-dose cefepime regimen in febrile neutropenic patients with hematological malignancies. Antimicrobial Agents and Chemotherapy, 59(9), 5463-5469.
DOI Scopus24 WoS24 Europe PMC22
2014 Sime, F. B., Roberts, M. S., Warner, M. S., Hahn, U., Robertson, T. A., Yeend, S., . . . Roberts, J. A. (2014). Altered pharmacokinetics of piperacillin in febrile neutropenic patients with hematological malignancy. Antimicrobial Agents and Chemotherapy, 58(6), 3533-3537.
DOI Scopus38 WoS37 Europe PMC34
2014 Reeve, E., Shakib, S., Hendrix, I., Roberts, M., & Wiese, M. (2014). The benefits and harms of deprescribing. Medical Journal of Australia, 201(7), 386-389.
DOI Scopus92 WoS70 Europe PMC61
2014 Reeve, E., Shakib, S., Hendrix, I., Roberts, M., & Wiese, M. (2014). Review of deprescribing processes and development of an evidence-based, patient-centred deprescribing process. British Journal of Clinical Pharmacology, 78(4), 738-747.
DOI Scopus302 WoS277 Europe PMC224
2014 Wunnapuk, K., Mohammed, F., Gawarammana, I., Liu, X., Verbeeck, R. K., Buckley, N. A., . . . Musuamba, F. T. (2014). Prediction of paraquat exposure and toxicity in clinically ill poisoned patients : a model based approach. British journal of clinical pharmacology, 78(4), 855-866.
DOI WoS33
2014 Wunnapuk, K., Gobe, G., Endre, Z., Peake, P., Grice, J. E., Roberts, M. S., . . . Liu, X. (2014). Use of a glyphosate-based herbicide-induced nephrotoxicity model to investigate a panel of kidney injury biomarkers. Toxicology letters, 225(1), 192-200.
DOI Scopus56 WoS51 Europe PMC40
2014 Kuswahyuning, R., & Roberts, M. S. (2014). Concentration dependency in nicotine skin penetration flux from aqueous solutions reflects vehicle induced changes in nicotine stratum corneum retention. Pharmaceutical research, 31(6), 1501-1511.
DOI
2014 Wunnapuk, K., Liu, X., Gobe, G. C., Endre, Z. H., Peake, P. W., Grice, J. E., . . . Buckley, N. A. (2014). Kidney biomarkers in MCPA-induced acute kidney injury in rats : reduced clearance enhances early biomarker performance. Toxicology letters, 225(3), 467-478.
DOI Scopus11 WoS10 Europe PMC9
2014 Sime, F. B., Roberts, M. S., Roberts, J. A., & Robertson, T. A. (2014). Simultaneous determination of seven β-lactam antibiotics in human plasma for therapeutic drug monitoring and pharmacokinetic studies. Journal of chromatography B, 960, 134-144.
DOI
2014 Krishnan, G., Roberts, M. S., Grice, J., Anissimov, Y. G., Moghimi, H. R., & Benson, H. A. E. (2014). Iontophoretic skin permeation of peptides : an investigation into the influence of molecular properties, iontophoretic conditions and formulation parameters. Drug delivery and translational research, 4(3), 222-232.
DOI
2014 Chandrasekaran, N. C., Weir, C., Alfraji, S., Grice, J., Roberts, M. S., & Barnard, R. T. (2014). Effects of magnesium deficiency-more than skin deep. Experimental biology and medicine, 239(10), 1280-1291.
DOI
2014 Wong, G., Brinkman, A., Benefield, R. J., Carlier, M., Roberts, M. S., Robertson, T. A., . . . Roberts, J. A. (2014). An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units. Journal of antimicrobial chemotherapy, 69(5, article no. dkt523), 1416-1423.
DOI
2014 Mohammed, Y. H., Yamada, M., Lin, L. L., Grice, J. E., Roberts, M. S., Raphael, A. P., . . . Prow, T. W. (2014). Microneedle enhanced delivery of cosmeceutically relevant peptides in human skin. PLoS one, 9(7, article no. e101956), 1-9.
DOI
2014 Thorling, C. A., Roberts, M. S., Liu, X., Fletcher, L. M., Crawford, D., & Burczynski, F. J. (2014). Effects of long-term hepatic ischemia-reperfusion injury on the function of P-glycoprotein in vivo in rats. Journal of pharmacy and pharmaceutical sciences, 17(1), 121-135.
DOI Scopus9 WoS9 Europe PMC6
2014 Thorling, C. A., Crawford, D., Burczynski, F. J., Liu, X., Liau, I., & Roberts, M. S. (2014). Multiphoton microscopy in defining liver function. Journal of biomedical optics, 19(9, article no. 090901), 1-11.
DOI Scopus37 WoS31 Europe PMC24
2014 McNeilly, C. L., Crichton, M. L., Primiero, C. A., Frazer, I. H., Roberts, M. S., & Kendall, M. A. F. (2014). Microprojection arrays to immunise at mucosal surfaces. Journal of controlled release, 196, 252-260.
DOI
2014 Liu, X., Kruger, P., Maibach, H., Colditz, P. B., & Roberts, M. S. (2014). Using skin for drug delivery and diagnosis in the critically ill. Advanced drug delivery reviews, 77, 40-49.
DOI Scopus36 WoS31 Europe PMC19
2013 Mahmood, A., Grice, J. E., Roberts, M. S., & Prow, T. W. (2013). Feasibility of multiphoton microscopy-based quantification of antibiotic uptake into neutrophil granulocytes. Journal of biomedical optics, 18(7), 1-6.
DOI
2013 Liu, X., Jin, L., Upham, J. W., & Roberts, M. S. (2013). The development of models for the evaluation of pulmonary drug disposition. Expert opinion on drug metabolism & toxicology, 9(4), 487-505.
DOI Scopus15 WoS13 Europe PMC8
2013 Roberts, M. S. (2013). Preface - Skin pharmacology and physiology. Skin pharmacology and physiology, 26(4-6), 179-180.
DOI
2013 Roberts, M. S. (2013). Solute-vehicle-skin interactions in percutaneous absorption: the principles and the people. Skin pharmacology and physiology, 26(4), 356-370.
DOI
2013 Krishnan, G., Grice, J. E., Roberts, M. S., Benson, H. A. E., & Prow, T. W. (2013). Enhanced sonophoretic delivery of 5-aminolevulinic acid : preliminary human ex vivo permeation data. Skin research and technology, 19(1), e283-e289.
DOI
2013 Jepps, O. G., Dancik, Y., Anissimov, Y. G., & Roberts, M. S. (2013). Modeling the human skin barrier - towards a better understanding of dermal absorption. Advanced drug delivery reviews, 65(2), 152-168.
DOI
2013 Robertson, T. A., Bunel, F., & Roberts, M. S. (2013). Fluorescein derivatives in intravital fluorescence imaging. Cells, 2(3), 591-606.
DOI
2013 Dancik, Y., Favre, A., Loy, C. J., Zvyagin, A. V., & Roberts, M. S. (2013). Use of multiphoton tomography and fluorescence lifetime imaging to investigate skin pigmentation in vivo. Journal of biomedical optics, 18(2, article no. 026022), 1-13.
DOI
2013 Wunnapuk, K., Liu, X., Peake, P., Gobe, G., Endre, Z., Grice, J. E., . . . Buckley, N. A. (2013). Renal biomarkers predict nephrotoxicity after paraquat. Toxicology letters, 222(3), 280-288.
DOI Scopus50 WoS43 Europe PMC30
2013 Liang, X. W., Xu, Z. P., Grice, J. E., Zvyagin, A., Roberts, M. S., & Liu, X. (2013). Penetration of nanoparticles into human skin. Current pharmaceutical design, 19(35), 6353-6366.
DOI Scopus69 WoS57 Europe PMC38
2013 Weiss, M., Liu, X., Thompson, C. A., & Roberts, M. S. (2013). Functional characterization of hepatic transporters using intravital microscopy. European journal of pharmaceutical sciences, 49(5), 845-849.
DOI Scopus9 WoS8 Europe PMC7
2013 Leite Silva, V. R., Le Lamer, M., Sanchez, W. Y., Liu, D. C., Sanchez, W. H., Morrow, I., . . . Roberts, M. S. (2013). The effect of formulation on the penetration of coated and uncoated zinc oxide nanoparticles into the viable epidermis of human skin in vivo. European journal of pharmaceutics and biopharmaceutics, 84(2), 297-308.
DOI Scopus115 Europe PMC63
2013 Thorling, C. A., Liu, X., Burczynski, F. J., Fletcher, L. M., Roberts, M. S., & Sanchez, W. Y. (2013). Intravital multiphoton microscopy can model uptake and excretion of fluorescein in hepatic ischemia-reperfusion injury. Journal of biomedical optics, 18(10, article no. 101306), 1-11.
DOI Scopus28 WoS26 Europe PMC17
2013 Mutalik, S., Parekh, H. S., Anissimov, Y. G., Grice, J. E., & Roberts, M. S. (2013). Iontophoresis-mediated transdermal permeation of peptide dendrimers across human epidermis. Skin pharmacology and physiology, 26(3), 127-138.
DOI
2013 Raphael, A. P., Sundh, D., Grice, J. E., Roberts, M. S., Soyer, H. P., & Prow, T. W. (2013). Zinc oxide nanoparticle removal from wounded human skin. Nanomedicine, 8(11), 1751-1761.
DOI
2013 Sanchez, W., Obispo, C., Ryan, E., Grice, J. E., & Roberts, M. S. (2013). Changes in the redox state and endogenous fluorescence of in vivo human skin due to intrinsic and photo-aging, measured by multiphoton tomography with fluorescence lifetime imaging. Journal of Biomedical Optics, 18(6), 1-13.
DOI
2013 Anissimov, Y. G., Jepps, O. G., Dancik, Y., & Roberts, M. S. (2013). Mathematical and pharmacokinetic modelling of epidermal and dermal transport processes. Advanced drug delivery reviews, 65(2), 169-190.
DOI
2013 Reeve, E., Wiese, M., Hendrix, I., Roberts, M., & Shakib, S. (2013). People's attitudes, beliefs, and experiences regarding polypharmacy and willingness to deprescribe. Journal of the American Geriatrics Society, 61(9), 1508-1514.
DOI Scopus197 WoS173 Europe PMC157
2013 Reeve, E., To, J., Hendrix, I., Shakib, S., Roberts, M., & Wiese, M. (2013). Patient barriers to and enablers of deprescribing: a systematic review. Drugs and Aging, 30(10), 793-807.
DOI Scopus415 WoS393 Europe PMC354
2013 Reeve, E., Shakib, S., Hendrix, I., Roberts, M., & Wiese, M. (2013). Development and validation of the patients' attitudes towards deprescribing (PATD) questionnaire. International Journal of Clinical Pharmacy, 35(1), 51-56.
DOI Scopus94 WoS89 Europe PMC83
2013 Arab, H. A., Cheung, K., Hickman, P. E., Potter, J. M., Walker, N. I., & Roberts, M. S. (2013). A comparison of hepatic ischemia/hypoxia-reperfusion injury models. Journal of pharmacological and toxicological methods, 68(3), 349-356.
DOI WoS2
2013 Smith, D., Timonen, H., Jaffe, D., Griffin, D., Birmele, M., Perry, K., . . . Roberts, M. (2013). Intercontinental dispersal of bacteria and archaea by transpacific winds. Applied and Environmental Microbiology, 79(4), 1134-1139.
DOI Scopus211 WoS192 Europe PMC117
2013 Zhang, Q., Li, P., Liu, D., & Roberts, M. S. (2013). Effect of vehicles on the maximum transepidermal flux of similar size phenolic compounds. Pharmaceutical research, 30(1), 32-40.
DOI Scopus28 WoS25 Europe PMC22
2013 Song, Z., Anissimov, Y., Zhao, J., Nechaev, A., Nadort, A., Jin, D., . . . Zvyagin, A. (2013). Background free imaging of upconversion nanoparticle distribution in human skin. Journal of Biomedical Optics, 18(6), 061215-1-061215-10.
DOI Scopus44 WoS37 Europe PMC19
2013 Kruger, P., Bailey, M., Bellomo, R., Cooper, D. J., Harward, M., Higgins, A., . . . Venkatesh, B. (2013). A multicenter randomized trial of atorvastatin therapy in intensive care patients with severe sepsis. American Journal of Respiratory and Critical Care Medicine, 187(7), 743-750.
DOI Scopus200 WoS190 Europe PMC147
2012 Anissimov, Y. G., Zhao, X., Roberts, M. S., & Zvyagin, A. V. (2012). Fluorescence recovery after photo-bleaching as a method to determine local diffusion coefficient in the stratum corneum. International journal of pharmaceutics, 435(1), 93-97.
DOI Scopus18 WoS17 Europe PMC13
2012 Li, P., Weise, M., & Roberts, M. S. (2012). Hepatic interaction between quinidine and digoxin: role of inhibition of sinusoidal Na+/K+ ATPase digoxin binding. European journal of pharmaceutical sciences, 47(2), 506-511.
DOI Scopus2 WoS2 Europe PMC2
2012 Roberts, D. M., Roberts, J. A., Roberts, M. S., Liu, X., Nair, P., Cole, L., . . . Bellomo, R. (2012). Variability of antibiotic concentrations in critically ill patients receiving continuous renal replacement therapy: a multicentre pharmacokinetic study. Critical Care Medicine, 40(5), 1523-1528.
DOI Scopus187 WoS177 Europe PMC151
2012 Weise, M., Li, P., & Roberts, M. S. (2012). Estimation of sinusoidal flow heterogeneity in normal and diseased rat livers from tracer dilution data using a fractal model. Microcirculation, 19(8), 723-728.
DOI Scopus3 WoS3 Europe PMC3
2012 Li, P., Robertson, T. A., Zhang, Q., Fletcher, L. M., Crawford, D. H. G., Weise, M., & Roberts, M. S. (2012). Hepatocellular necrosis, fibrosis and microsomal activity determine the hepatic pharmacokinetics of basic drugs in right-heart-failure-induced liver damage. Pharmaceutical research, 29(6), 1658-1669.
DOI Scopus12 WoS11 Europe PMC11
2012 Kaur, S., Roberts, J. A., & Roberts, M. S. (2012). Evaluation of medication-related problems in medication reviews : a comparative perspective. Annals of pharmacotherapy, 46(7-8), 972-982.
DOI Scopus17 WoS17 Europe PMC15
2012 Sinnollareddy, M., Peake, S., Roberts, M., Lipman, J., & Roberts, J. (2012). Using pharmacokinetics and pharmacodynamics to optimise dosing of antifungal agents in critically ill patients: a systematic review. International Journal of Antimicrobial Agents, 39(1), 1-10.
DOI Scopus47 WoS44 Europe PMC36
2012 Sime, F., Roberts, M., Peake, S., Lipman, J., & Roberts, J. (2012). Does Beta-lactam pharmacokinetic variability in critically ill patients justify therapeutic drug monitoring? A systematic review. Annals of Intensive Care, 2(35), 1-11.
DOI Scopus165 WoS145 Europe PMC124
2012 Mahmood, A. H., Medley, G. A., Grice, J. E., Liu, X., & Roberts, M. S. (2012). Determination of trovafloxacin and marbofloxacin in sheep plasma samples by HPLC using UV detection. Journal of pharmaceutical and biomedical analysis, 62, 220-223.
DOI Scopus19 WoS15 Europe PMC7
2012 Gilbert, A., Patel, B., Morrow, M., Williams, D., Roberts, M. S., & Gilbert, A. L. (2012). Providing community-based health practitioners with timely and accurate discharge medicines information. BMC health services research, 12(1), 1-7.
DOI
2012 Dancik, Y., Anissimov, Y. G., Jepps, O. G., & Roberts, M. S. (2012). Convective transport of highly plasma protein bound drugs facilitates direct penetration into deep tissues after topical application. British journal of clinical pharmacology, 73(4), 564-578.
DOI
2012 Sinnollareddy, M. G., Roberts, M. S., Lipman, J., & Roberts, J. A. (2012). ß-lactam pharmacokinetics and pharmacodynamics in critically ill patients and strategies for dose optimization : a structured review. Clinical and experimental pharmacology and physiology, 39(6), 489-496.
DOI
2012 Liu, X., Thorling, C. A., Jin, L., & Roberts, M. S. (2012). Intravital multiphoton imaging of rhodamine 123 in the rat liver after intravenous dosing. IntraVital, 1(1), 54-59.
DOI
2012 Liu, D. C., Raphael, A. P., Sundh, D., Grice, J. E., Soyer, H. P., Roberts, M. S., & Prow, T. W. (2012). The human stratum corneum prevents small gold nanoparticle penetration and their potential toxic metabolic consequences. Journal of nanomaterials, 2012(721706), 1-8.
DOI Scopus27
2012 Leite Silva, V. R., de Almeida, M. M., Fradin, A., Grice, J. E., & Roberts, M. S. (2012). Delivery of drugs applied topically to the skin. Expert review of dermatology, 7(4), 383-397.
DOI
2012 Liu, X., Kruger, P. S., Weise, M., & Roberts, M. S. (2012). The pharmacokinetics and pharmacodynamics of cisatracurium in critically ill patients with severe sepsis. British journal of clinical pharmacology, 73(5), 741-749.
DOI Scopus13 WoS12 Europe PMC7
2012 Prow, T. W., Monteriro Riviere, N. A., Inman, A. O., Grice, J. E., Chen, X., Zhao, X., . . . Roberts, M. S. (2012). Quantum dot penetration into viable human skin. Nanotoxicology, 6(2), 173-185.
DOI Scopus101 WoS85 Europe PMC59
2012 Wiechers, J. W., Watkinson, A. C., Cross, S. E., & Roberts, M. S. (2012). Predicting skin penetration of actives from complex cosmetic formulations: an evaluation of inter formulation and inter active effects during formulation optimization for transdermal delivery. International journal of cosmetic science, 34(6), 525-535.
DOI
2011 Wunnapuk, K., Medley, G. A., Liu, X., Grice, J. E., Jayasinghe, S., Gawarammana, I., . . . Roberts, M. S. (2011). Simple and sensitive liquid chromatography-tandem mass spectrometry methods for quantification of paraquat in plasma and urine: application to experimental and clinical toxicological studies. Journal of chromatography B: analytical technologies in the biomedical and life sciences, 879(28), 3047-3052.
DOI Scopus42 WoS40 Europe PMC22
2011 Wu, Y. T., Anissimov, Y. G., & Roberts, M. S. (2011). Introduction to dermatokinetics. Dermatokinetics of Therapeutic Agents, 1-23.
DOI Scopus6
2011 Song, Z., Kelf, T., Sanchez, W. H., Roberts, M. S., Rička, J., Frenz, M., & Zvyagin, A. (2011). Characterization of optical properties of ZnO nanoparticles for quantitative imaging of transdermal transport. Biomedical Optics Express, 2(12), 3321-3333.
DOI Scopus116 WoS95
2011 Liu, X., Kruger, P. S., & Roberts, M. S. (2011). How to measure pharmacokinetics in critically ill patients?. Current Pharmaceutical Biotechnology, 12(12), 2037-2043.
DOI Scopus6 WoS5 Europe PMC5
2011 Monajjemzadeh, F., Hassanzadeh, D., Valizadeh, H., Siahi Shadbad, M. R., Mojarrad, J. S., Robertson, T. A., & Roberts, M. S. (2011). Detection of gabapentin-lactose maillard reaction product (Schiff's base): application to solid dosage form preformulation / Part 1. Pharmazeutische Industrie, 73(1), 174-177.
2011 Monajjemzadeh, F., Hassanzadeh, D., Valizadeh, H., Siahi Shadbad, M. R., Mojarrad, J. S., Robertson, T. A., & Roberts, M. S. (2011). Detection of gabapentin-lactose Maillard reaction product (Schiff's Base): Application to solid dosage form preformulation / Part 2. Pharmazeutische industrie, 73(2), 376-382.
2011 Mitragotri, S., Anissimov, Y. G., Bunge, A. L., Frasch, H. F., Guy, R. H., Hadgraft, J., . . . Roberts, M. S. (2011). Mathematical models of skin permeability: an overview. International journal of pharmaceutics, 418(1), 115-129.
DOI
2011 Krishnan, G., Roberts, M. S., Grice, J., Anissimov, Y. G., & Benson, H. A. E. (2011). Enhanced transdermal delivery of 5-aminolevulinic acid and a dipeptide by iontophoresis. Biopolymers, 96(2), 166-171.
DOI
2011 Davies, P. G., Venkatesh, B., Morgan, T. J., Presneill, J. J., Kruger, P. S., Thomas, B. J., . . . Mundy, J. (2011). Plasma acetate, gluconate and interleukin-6 profiles during and after cardiopulmonary bypass: a comparison of Plasma-Lyte 148 with a bicarbonate-balanced solution. Critical care, 15(1), R21-1-R21-8.
DOI
2011 Thorling, C. A., Dancik, Y., Hupple, C. W., Medley, G., Liu, X., Zvyagin, A. V., . . . Roberts, M. S. (2011). Multiphoton microscopy and fluorescence lifetime imaging provide a novel method in studying drug distribution and metabolism in the rat liver in vivo. Journal of biomedical optics, 16(8), 086013.1-086013.7.
DOI Scopus18 WoS15 Europe PMC12
2011 Lin, L. L., Grice, J. E., Butler, M. K., Zvyagin, A. V., Becker, W., Robertson, T. A., . . . Prow, T. W. (2011). Time-correlated single photon counting for simultaneous monitoring of zinc oxide nanoparticles and NAD(P)H in intact and barrier-disrupted volunteer skin. Pharmaceutical research, 28(11), 2920-2930.
DOI
2011 Liu, X., Grice, J. E., Lademann, J., Otberg, N., Trauer, S., Patzelt, A., & Roberts, M. S. (2011). Hair follicles contribute significantly to penetration through human skin only at times soon after application as a solvent deposited solid in man. British journal of clinical pharmacology, 72(5), 768-774.
DOI Scopus94 WoS80 Europe PMC54
2011 Labouta, H. I., Liu, D. C., Lin, L. L., Butler, M. K., Grice, J. E., Raphael, A. P., . . . Prow, T. W. (2011). Gold nanoparticle penetration and reduced metabolism in human skin by toluene. Pharmaceutical research, 28(11), 2931-2944.
DOI Scopus87 Europe PMC43
2011 König, K., Raphael, A. P., Lin, L., Grice, J. E., Soyer, H. P., Breuing, H. G., . . . Prow, T. W. (2011). Applications of multiphoton tomographs and femtosecond laser nanoprocessing microscopes in drug delivery research. Advanced drug delivery reviews, 63(4-5), 388-404.
DOI
2011 Thorling, C. A., Liu, X., Burczynski, F. J., Fletcher, L. M., Gobe, G. C., & Roberts, M. S. (2011). Multiphoton microscopy can visualize zonal damage and decreased cellular metabolic activity in hepatic ischemia-reperfusion injury in rats. Journal of biomedical optics, 16(11, article no. 116011), 1-8.
DOI Scopus31 WoS27 Europe PMC17
2011 Anissimov, Y. G., & Roberts, M. S. (2011). Modelling dermal drug distribution after topical application in human. Pharmaceutical research, 28(9), 2119-2129.
DOI
2011 Fanning, K. J., Robertson, T. A., Prins, J. B., & Roberts, M. S. (2011). Changes in antibiotic distribution due to pancreatitis. Antimicrobial agents and chemotherapy, 55(6), 3008-3011.
DOI
2011 Kruger, P., Harward, M. L., Jones, M., Joyce, C. J., Kostner, K. M., Roberts, M. S., & Venkatesh, B. (2011). Continuation of statin therapy in patients with presumed infection:a randomized controlled trial. American journal of respiratory and critical care medicine, 183(6), 774-781.
DOI
2011 Prow, T. W., Grice, J. E., Lin, L. L., Faye, R., Butler, M., Becker, W., . . . Roberts, M. S. (2011). Nanoparticles and microparticles for skin drug delivery. Advanced drug delivery reviews, 63(6), 470-491.
DOI
2011 Roberts, M. S., Dancik, Y., Prow, T. W., Thompson, C. A., Lin, L. L., Grice, J. E., . . . Becker, W. (2011). Non-invasive imaging of skin physiology and percutaneous penetration using fluorescence spectral and lifetime imaging with multiphoton and confocal microscopy. European journal of pharmaceutics and biopharmaceutics, 77(3), 469-488.
DOI
2011 Roberts, M. S., Liu, X., Zou, Y., Siebert, G. A., Chang, P., Whitehouse, M. W., . . . Crawford, D. H. G. (2011). Effect of adjuvant-induced systemic inflammation in rats on hepatic disposition kinetics of taurocholate. American journal of physiology: gastrointestinal and liver physiology, 300(1), 130-136.
DOI Scopus6 WoS7 Europe PMC5
2011 Mostafa, A., Medley, G., Roberts, D. M., Mohamed, M. S., Elshanawani, A. A., Roberts, M. S., & Liu, X. (2011). Simultaneous quantification of carbamate insecticides in human plasma by liquid chromatography/tandem mass spectrometry. Journal of chromatography B: analytical technologies in the biomedical and life sciences, 879(23), 2234-2238.
DOI Scopus18 WoS17 Europe PMC11
2011 Roberts, D. M., Wilks, M. F., Roberts, M. S., Swaminathan, R., Mohamed, F., Dawson, A., & Buckley, N. A. (2011). Changes in the concentrations of creatinine, cystatin C and NGAL in patients with acute paraquat self-poisoning. Toxicology letters, 202(1), 69-74.
DOI Scopus48 WoS44 Europe PMC38
2011 Zhou, F., Zhang, J., Li, P., Niu, F., Wu, X., Wang, G., & Roberts, M. S. (2011). Toward a new age of cellular pharmacokinetics in drug discovery. Drug metabolism reviews, 43(3), 335-345.
DOI Scopus57 WoS47 Europe PMC40
2011 Zhang, Q., Li, P., & Roberts, M. S. (2011). Maximum transepidermal flux for similar size phenolic compounds is enhanced by solvent uptake into the skin. Journal of controlled release, 154(1), 50-57.
DOI Scopus48 WoS42 Europe PMC32
2011 Sinnollareddy, M., Peake, S., Roberts, M., Playford, E., Lipman, J., & Roberts, J. (2011). Pharmacokinetic evaluation of fluconazole in critically ill patients. Expert Opinion on Drug Metabolism and Toxicology, 7(11), 1431-1440.
DOI Scopus14 WoS12 Europe PMC10
2011 Li, P., Robertson, T. A., Thompson, C. A., Zhang, Q., Fletcher, L. M., Crawford, D. H. G., & Roberts, M. S. (2011). Hepatic pharmacokinetics of cationic drugs in a high-fat emulsion-induced rat model of nonalcoholic steatohepatitis. Drug metabolism and disposition, 39(4), 571-579.
DOI Scopus28 WoS28 Europe PMC24
2011 Douglas, A., Altukroni, M., Udy, A. A., Roberts, M. S., Taraporewalla, K., Jenkins, J., . . . Roberts, J. A. (2011). The pharmacokinetics of cefazolin in patients undergoing elective & semi-elective abdominal aortic aneurysm open repair surgery. BMC anesthesiology, 11(article no. 5), 1-5.
DOI Scopus8
2011 Douglas, A., Udy, A. A., Wallis, S. C., Jarrett, P., Stuart, J., Lassig Smith, M., . . . Roberts, J. A. (2011). Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery. Antimicrobial Agents and Chemotherapy, 55(11), 5238-5242.
DOI Scopus72 Europe PMC61
2011 Roberts, J. A., Roberts, M. S., Semark, A., Udy, A. A., Kirkpatrick, C. M. J., Paterson, D. L., . . . Lipman, J. (2011). Antibiotic dosing in the 'at risk' critically ill patient : linking pathophysiology with pharmacokinetics/pharmacodynamics in sepsis and trauma patients. BMC Anesthesiology, 11(3), 1-7.
DOI Scopus46
2010 Park, S., Kim, S., Ropella, G., Roberts, M. S., & Hunt, A. (2010). Tracing multiscale mechanisms of drug disposition in normal and diseased livers. Journal of pharmacology and experimental therapeutics, 334(1), 124-136.
DOI Scopus28 Europe PMC20
2010 Zou, Y. H., Liu, X., Khlentzos, A. M., Asadian, P., Li, P., Thorling, C. A., . . . Roberts, M. S. (2010). Liver fibrosis impairs hepatic pharmacokinetics of liver transplant drugs in the rat model. Drug Metabolism and Pharmacokinetics, 25(5), 442-449.
DOI Scopus5 WoS4 Europe PMC4
2010 Liu, X., Zou, Y., Khlentzos, A. M., Yang, Y., Nikolovski, J., Weiss, M., & Roberts, M. S. (2010). Nitric oxide induced sinusoidal relaxation after a propranolol priming dose in the perfused rat liver reduces propranolol availability on subsequent dosing. Clinical and experimental pharmacology and physiology, 37(10), 1028-1033.
DOI
2010 Fernando, G. J. P., Chen, X., Prow, T. W., Crichton, M. L., Fairmaid, E. J., Roberts, M. S., . . . Kendall, M. A. F. (2010). Potent immunity of low doses of influenza vaccine by probalistic guided micro-targeted skin delivery in a mouse model. PLoS one, 5(4), e10266.
DOI
2010 Roberts, J., Kirkpatrick, C., Roberts, M. S., Dalley, A., & Lipman, J. (2010). First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis. International journal of antimicrobial agents, 35(2), 156-163.
DOI
2010 Geusens, B., Van Gele, M., Braat, S., De Smedt, S. C., Stuart, M. C. A., Prow, T. W., . . . Lambert, J. (2010). Flexible nanosomes (SECosomes) enable efficient siRNA delivery in cultured primary skin cells and in the viable epidermis of ex vivo human skin. Advanced functional materials, 20(23), 4077-4090.
DOI
2010 Green, B., Chandler, S., MacDonald, G., Elliott, G., & Roberts, M. S. (2010). Quantifying pain relief following administration of a novel formulation of paracetamol (acetaminophen). Journal of clinical pharmacology, 50(12), 1406-1413.
DOI
2010 Roberts, M. S. (2010). Drug structure-transport relationships. Journal of pharmacokinetics and pharmacodynamics, 37(6), 541-573.
DOI
2010 Hickman, P., Potter, J., Aroney, C., Koerbin, G., Southcott, E., Wu, A. H. B., & Roberts, M. S. (2010). Cardiac troponin may be released by ischemia alone, without necrosis. Clinica chimica acta, 411(5-6), 318-323.
DOI
2010 Gawarammana, I. B., Roberts, D. M., Mohamed, F., Roberts, M. S., Medley, G., Jayamanne, S., & Dawson, A. (2010). Acute human self-poisoning with bispyribac-containing herbicide Nominee®: a prospective observational study. Clinical Toxicology, 48(3), 198-202.
DOI Scopus8 Europe PMC3
2010 Prow, T. W., Chen, X., Prow, N. A., Fernando, G. J. P., Tan, C. S. E., Raphael, A. P., . . . Kendall, M. A. F. (2010). Nanopatch-targeted skin vaccination against West Nile virus and Chikungunya virus in mice. Small, 6(16), 1776-1784.
DOI
2010 Popov, A. P., Zvyagin, A., Lademann, J., Roberts, M. S., Sanchez, W. Y., Priezzhev, A. U., & Myllyla, R. (2010). Designing inorganic light-protective skin nanotechnology products. Journal of Biomedical Nanotechnology, 6(SI5), 432-451.
2010 Xia, C. H., Sun, J. G., Wang, G. J., Shang, L. L., Zhang, X. X., Zhang, R., . . . Roberts, M. S. (2010). Herb-drug interactions : in vivo and in vitro effect of shenmai injection, a herbal preparation, on the metabolic activities of hepatic cytochrome P450 3A1/2, 2C6, 1A2, and 2E1 in rats. Planta medica, 76(3), 245-250.
DOI
2010 Grice, J. E., Ciotti, S., Weiner, N., Lockwood, P., Cross, S., & Roberts, M. S. (2010). Relative uptake of minoxidil into appendages and stratum corneum and permeation through human skin in vitro. Journal of pharmaceutical sciences, 99(2), 712-718.
DOI
2010 Sanchez, W. Y., Prow, T. W., Sanchez, W. H., Grice, J. E., & Roberts, M. S. (2010). Analysis of the metabolic deterioration of ex vivo skin from ischemic necrosis through the imaging of intracellular NAD(P)H by multiphoton tomography and fluorescence lifetime imaging microscopy. Journal of biomedical optics, 15(4), 046008.1-046008.11.
DOI
2010 Liu, X., Yang, Y., Zhang, X., Xu, S., He, S., Huang, W., & Roberts, M. S. (2010). Compound Astragalus and Salvia miltiorrhiza extract inhibits cell invasion by modulating transforming growth factor-B/Smad in HepG2 cell. Journal of gastroenterology and hepatology, 25(2), 420-426.
DOI
2010 Weiss, M., Li, P., & Roberts, M. S. (2010). An improved nonlinear model describing the hepatic pharmacokinetics of digoxin : evidence for two functionally different uptake systems and saturable binding. Pharmaceutical research, 27(9), 1999-2007.
DOI
2010 Grice, J. E., Cross, S., Brownlie, C., & Roberts, M. S. (2010). The application of molecular structural predictors of intestinal absorption to screening of compounds for transdermal penetration. Journal of pharmacy and pharmacology, 62(6), 750-755.
DOI WoS9
2010 Roberts, J., Ulldemolins, M., Roberts, M. S., McWhinney, B., Ungerer, J., Paterson, D., & Lipman, J. (2010). Therapeutic drug monitoring of β-lactams in critically ill patients : proof of concept. International journal of antimicrobial agents, 36(4), 332-339.
DOI
2010 He, S., Liu, X., Yang, Y., Huang, W., Xu, S., Yang, S., . . . Roberts, M. S. (2010). Mechanisms of transforming growth factor β1/Smad signalling mediated by mitogen-activated protein kinase pathways in keloid fibroblast. British journal of dermatology, 162(3), 538-546.
DOI
2009 Liu, X., Wang, J. Y., Khlentzos, A. M., Fontaine, F., Nikolovski, J., Goh, L. A., & Roberts, M. S. (2009). Influence of perfusate composition on drug disposition in the in-situ perfused rat lung. International journal of pharmaceutics, 382(1-2), 192-197.
DOI Scopus7 WoS7 Europe PMC3
2009 Roberts, J. A., Roberts, M. S., Robertson, T. A., Dalley, A. J., & Lipman, J. (2009). Piperacillin penetration into tissue of critically ill patients with sepsis-bolus versus continuous administration?. Critical care medicine, 37(3), 926-933.
DOI
2009 Monajjemzadeh, F., Hassanzadeh, D., Valizadeh, H., Siahi Shadbad, M. R., Mojarrad, J. S., Robertson, T. A., & Roberts, M. S. (2009). Compatibility studies of acyclovir and lactose in physical mixtures and commercial tablets. European journal of pharmaceutics and biopharmaceutics, 73(3), 404-413.
DOI
2009 Li, P., Wang, G. J., Robertson, T. A., & Roberts, M. S. (2009). Liver transporters in hepatic drug disposition: an update. Current drug metabolism, 10(5), 482-498.
DOI Scopus33 WoS30 Europe PMC23
2009 Mohamed, F., Gawarammana, I., Robertson, T. A., Roberts, M. S., Palangasinghe, C., Zawahir, S., . . . Roberts, D. M. (2009). Acute human self-poisoning with imidacloprid compound: a neonicotinoid insecticide. PLoS one, 4(4, article no. e5127), 1-5.
DOI Scopus120 WoS105 Europe PMC83
2009 Qian, Z., Grice, J. E., Li, P., Jepps, O. G., Wang, G. J., & Roberts, M. S. (2009). Skin solubility determines maximum transepidermal flux for similar size molecules. Pharmaceutical Research, 26(8), 1974-1985.
DOI Scopus82 WoS71 Europe PMC57
2009 Chen, X., Prow, T. W., Crichton, M. L., Jenkins, D. W. K., Roberts, M. S., Frazer, I. H., . . . Kendall, M. A. F. (2009). Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin. Journal of controlled release, 139(3), 212-220.
DOI
2008 Nohynek, G., Dufour, E., & Roberts, M. S. (2008). Nanotechnology, cosmetics and the skin: is there a health risk?. Skin Pharmacology and Physiology, 21(3), 136-149.
DOI
2008 Cross, S., & Roberts, M. S. (2008). Use of in vitro human skin membranes to model and predict the effect of changing blood flow on the flux and retention of topically applied solutes. Journal of pharmaceutical sciences, 97(8), 3442-3450.
DOI
2008 Park, S., Ropella, G., Kim, S., & Roberts, M. S. (2008). Computational strategies unravel and trace how liver disease changes hepatic drug disposition. Journal of pharmacology and experimental therapeutics, 328(1), 294-305.
DOI
2008 Yan, L., Ropella, G., Park, S., Roberts, M. S., & Hunt, A. (2008). Modeling and simulation of hepatic drug disposition using a physiologically based, multi-agent in silico liver. Pharmaceutical Research, 25(5), 1023-1036.
DOI
2008 Winckle, G., Anissimov, Y., Cross, S., Wise, G., & Roberts, M. S. (2008). An integrated pharmacokinetic and imagine evaluation of vehicle effects on solute human epidermal flux and, retention characteristics. Pharmaceutical Research, 25(1), 158-166.
DOI
2008 Cross, S., Russel, M., Southwell, I., & Roberts, M. S. (2008). Human skin penetration of the major components of Australian tea tree oil applied in its pure form and as a 20% solution in vitro. European journal of pharmaceutics and biopharmaceutics, 69(1), 214-222.
DOI
2008 Roberts, M. S., Roberts, M., Robertson, T., Sanchez, W., Thorling, C., Zou, Y., . . . Zvyagin, A. (2008). In vitro and in vivo imaging of xenobiotic transport in human skin and in the rat liver. Journal of Biophotonics, 1(6), 478-493.
DOI
2008 Roberts, J., Roberts, M. S., Robertson, T. A., Cross, S., & Lipman, J. (2008). A novel way to investigate the effects of plasma exchange on antibiotic levels: use of microdialysis. International Journal of Antimicrobial Agents, 31(3), 240-244.
DOI
2008 Weiss, M., Hung, D., Poenicke, K., & Roberts, M. S. (2008). Kinetic analysis of saturable hepatic uptake of digoxin and its inhibition of rifampicin. European journal of pharmaceutical sciences, 34(4-5), 345-350.
DOI
2007 Fanning, K., & Roberts, M. S. (2007). Characterization of the physiological spaces and distribution of tolbutamide in the perfused rat pancreas. Pharmaceutical Research, 24(3), 512-520.
DOI
2007 Nohynek, G., Lademann, J., Ribaud, C., & Roberts, M. S. (2007). Grey goo on the skin? Nanotechnology, cosmetic and sunscreen safety. Critical Reviews in Toxicology, 37(3), 251-277.
DOI
2007 Mo, Y. K., Kankavi, O., Masci, P., Mellick, G., Whitehouse, M., Boyle, G., . . . Cross, S. (2007). Surfactant protein expression in human skin: evidence and implications. The Journal of Investigative Dermatology, 127(2), 381-386.
DOI
2007 Dalley, A., Lipman, J., Venkatesh, M., Rudd, M., Roberts, M. S., & Cross, S. (2007). Inadequate antimicrobial prophylaxis during surgery : a study of ß-lactam levels during burn debridement. Journal of Antimicrobial Chemotherapy, 60(1), 166-169.
DOI
2007 Wang, G., Shen, H., Rajaraman, G., Roberts, M. S., Yuewen, G., Ping, J., & Burzynski, F. (2007). Expression and antioxidant function of liver fatty acid binding protein in normal and bile-duct ligated rats. European Journal of Pharmacology, 560(1), 61-68.
DOI
2007 King, M., & Roberts, M. S. (2007). The influence of the Pharmaceutical Benefits Scheme (PBS) on inappropriate prescribing in Australian nursing homes. Pharmacy World and Science, 29(1), 39-42.
DOI
2007 Arab, H., Cheung, K., Hickman, P., Potter, J., Kadkhodaee, M., & Roberts, M. S. (2007). Effects of hypoxia/reperfusion injury on drug disposition in the rat isolated perfused liver. Clinical and Experimental Pharmacology and Physiology, 34(4), 332-338.
DOI
2007 Cross, S., Innes, B., Roberts, M. S., Tsuzuki, T., Robertson, T., & McCormick, P. (2007). Human skin penetration of sunscreen nanoparticles: In-vitro assessment of a novel micronized Zinc Oxide formulation. Skin Pharmacology and Physiology, 20(3), 148-154.
DOI
2007 Atrux Tallau, N., Pirot, F., Falson, F., Roberts, M. S., & Maibach, H. (2007). Qualitative and quantitative comparison of heat separated epidermis and dermatomed skin in percutaneous absorption studies. Archives of Dermatological Research, 299(10), 507-511.
DOI
2006 Hunt, A., Ropella, G., Yan, L., Hung, D., & Roberts, M. S. (2006). Physiologically based synthetic models of hepatic disposition. Journal of Pharmacokinetics and Pharmacodynamics, 33(6), 737-772.
DOI
2006 Magnusson, B., Cross, S., Winckle, G., & Roberts, M. S. (2006). Percutaneous absorption of steroids: determination of in vitro permeability and tissue reservoir characteristics in human skin layers. Skin Pharmacology and Physiology, 19(6), 336-342.
DOI
2006 Blazkiewicz, P., Blazkiewicz, K., Verhaege, A., Anissimov, Y., Roberts, M. S., & Zvyagin, A. (2006). Dialysis-assisted fiber optic spectroscopy for in situ biomedical sensing. Journal of Biomedical Optics, 11(1), 014033.
DOI
2006 Sorensen, L., Stokes, J., Purdie, D., Woodward, M. C., & Roberts, M. S. (2006). Medication management at home: medication risk factor prevalence and inter-relationships. Journal of Clinical Pharmacy and Therapeutics, 31(5), 485-491.
DOI
2006 Roberts, D., Southcott, E., Potter, J., Roberts, M. S., Eddleston, M., & Buckley, N. (2006). Pharmacokinetics of digoxin cross-reacting substances in patients with acute yellow oleander (Thevetia peruviona) poisoning including the effect of activated charcoal. Therapeutic Drug Monitoring, 28(6), 784-792.
DOI Scopus41 WoS30 Europe PMC24
2006 Mollee, T., Anissimov, Y., & Roberts, M. S. (2006). Periodic electric field enhanced transport through membranes. Journal of Membrane Science, 278(1-2), 290-300.
DOI
2006 Hung, D., Siebert, G., Chang, P., Whitehouse, M., Fletcher, L., Crawford, D., & Roberts, M. S. (2006). Hepatic pharmacokinetics of propranolol in rats with adjuvant-induced systemic inflammation. AJP - Gastrointestinal and Liver Physiology, 290(2), G343-G351.
DOI
2005 Hayden, C. G., Cross, S., Anderson, C., Saunders, N., & Roberts, M. S. (2005). Sunscreen penetration of human skin and related keratinocyte toxicity after topical application. Skin Pharmacology and Physiology, 18(4), 170-174.
DOI
2005 Sorensen, L., Stokes, J. A., Purdie, D. M., Woodward, M., & Roberts, M. S. (2005). Medication management at home: medication-related risk factors associated with poor health outcomes. Age And Ageing, 34(6), 626-632.
DOI
2005 Hung, D., Siebert, G., Chang, P., Burczynski, F., & Roberts, M. S. (2005). Reduced hepatic extraction of palmitate in steatosis correlated to lower level of liver fatty acid binding protein. AJP - Gastrointestinal and Liver Physiology, 288(1), G93-G100.
DOI
2005 Rajaraman, G., Roberts, M. S., Hung, D., Wang, G., & Burczynski, F. (2005). Membrane binding proteins are the major determinants for the hepatocellular transmembrane flux of long-chain fatty acids bound to albumin. Pharmaceutical Research.
2005 Hung, D., Siebert, G., Chang, P., & Roberts, M. S. (2005). Hepatic pharmacokinetics of taurocholate in the normal and cholestatic rat liver. British Journal of Pharmacology.
2005 Chang, P., Hung, D., Siebert, G., Bridle, K., & Roberts, M. S. (2005). Therapeutic effects and possible mechanisms of a snake venom preparation in the fibrotic rat liver. Digestive Diseases and Sciences, 50(4), 745-752.
DOI
2005 Xie, H. T., Wang, G. J., Chen, M., Jiang, X. L., Li, H., Lv, H., . . . Roberts, M. S. (2005). Uptake and metabolism of ginsenoside Rh2 and its aglycon protopanaxadiol by Caco-2 cells. Biological & Pharmaceutical Bulletin.
2005 Bjorkman, S., O'Driscoll, S., Burke, C., Roberts, M. S., & Colditz, P. (2005). Hypercapnic acidosis following hypoxia in newborn piglet, a potential neuroprotectant. Journal of Neurochemistry.
2005 Roberts, M. S., Cross, S., & Anissimov, Y. (2005). The skin reservoir for topically applied solutes. Drugs and the Pharmaceutical Sciences.
2005 Hao, H., Wang, G., Sun, J., Ding, Z., Wu, X., & Roberts, M. S. (2005). Unidirectional inversion of ibuprofen in Caco-2 cells : Developing a suitable model for presystemic chiral inversion study. Biological & Pharmaceutical Bulletin.
2005 Ientile, C., Sorensen, L., Lemanski, L., & Roberts, M. S. (2005). Complementary medicines use by Australian veterans. Journal of Pharmacy Practice and Research.
2005 Burczynski, F., Hung, D., Wang, G., Elmadhoun, B., Lewis, A., Chang, P., . . . Roberts, M. S. (2005). Assessing the cellular transmembrane electrical potential difference on the hepatic uptake of palmitate. Molecular and Cellular Biochemistry.
DOI
2005 Wang, G., Gong, Y., Anderson, J., Sun, D., Minuk, G., Roberts, M. S., & Burczynski, F. (2005). Antioxidative function of L-FABP in L-FABP stably transfected chang liver cells. Hepatology.
2005 Sarveiya, V., Roberts, M. S., & Risk, S. (2005). Influence of anatomical site and topical formulation on skin penetration of sunscreens. Therapeutics and Clinical Risk Management.
2005 Chilcott, R., Barai, N., Beezer, A., Brain, S., Brown, M., Bunge, A., . . . Roberts, M. S. (2005). Inter- and intralaboratory variation of in vitro diffusion cell measurements: an international multicenter study using quasi-standardized methods and materials. Journal of Pharmaceutical Sciences, 94(3), 632-638.
DOI
2004 Magnusson, B., Pugh, W., & Roberts, M. S. (2004). Simple rules defining the potential of compounds for transdermal delivery or toxicity. Pharmaceutical Research.
2004 Sorensen, L., Stokes, J., Purdie, D., Woodward, M. C., Elliott, R., & Roberts, M. S. (2004). Medication reviews in the community: results of a randomized, controlled effectiveness trial. British Journal of Clinical Pharmacology.
2004 Stokes, J., Purdie, D., & Roberts, M. S. (2004). Factors influencing PRN medication use in nursing homes. Pharmacy World and Science.
2004 Roberts, M. S., Anissimov, Y., & Cross, S. (2004). Factors affection the formation of a skin reservoir for topically applied solutes. Skin Pharmacology and Physiology, 17(1), 3-16.
DOI
2004 Sorensen, L., King, M., Peck, R., & Roberts, M. S. (2004). In-home medication reviews for war veterans: early experience in Australia. Journal of Pharmacy Practice and Research.
2004 Siebert, G., Hung, D., Chang, P., & Roberts, M. S. (2004). Ion-trapping, microsomal binding and unbound drug distribution in the hepatic retention of basic drugs. The Journal of Pharmacology and Experimental Therapeutics, 308(1), 228-235.
DOI
2004 Kankavi, O., & Roberts, M. S. (2004). Detection of surfactant protein A (SP-A) and surfactant protein D (SP-D) in equine synovial fluid with immunoblotting. Canadian Journal of Veterinary Research.
2004 Hung, D., Siebert, G., Chang, P., Anissimov, Y., & Roberts, M. S. (2004). Disposition kinetics of propranolol isomers in the perfused rat liver. The Journal of Pharmacology and Experimental Therapeutics, 311(2), 822-829.
DOI
2004 Magnusson, B. M., Anissimov, Y. G., Cross, S. E., & Roberts, M. S. (2004). Molecular size as the main determinant of solute maximum flux across the skin. Journal Of Investigative Dermatology, 122(4), 993-999.
DOI
2004 Mills, P., Siebert, G., & Roberts, M. S. (2004). A model to study intestinal and hepatic metabolism of propranolol in the dog. Journal of Veterinary Pharmacology and Therapeutics.
2004 Anissimov, Y., & Roberts, M. S. (2004). Diffusion modelling of percutaneous absorption kinetics: 3. Variable diffusion and partitioning coefficients. Journal of Pharmaceutical Sciences, 93(2), 470-487.
DOI
2004 Craft, J., Masci, P., Roberts, M. S., Brighton, T., Garrahy, P., Cox, S., & Marsh, N. (2004). Increased platelet-derived microparticles in the coronary circulation of percutaneous transluminal coronary angioplasty patients. Blood Coagulation and Fibrinolysis, 15(6), 475-482.
DOI Scopus20 Europe PMC7
2003 Mueller, B., Anissimov, Y., & Roberts, M. S. (2003). Unexpected clobetasol propionate profile in human stratum corneum after topical application in vitro. Pharmaceutical Research, 20(11), 1835-1837.
DOI
2003 Cross, S. E., Magnusson, B. M., Winckle, G., Anissimov, Y., & Roberts, M. S. (2003). Determination of the effect of lipophilicity on the in vitro permeability and tissue reservoir characteristics of topically applied solutes in human skin layers. Journal of Investigative Dermatology, 120(5), 759-764.
DOI
2003 Sorensen, L., Roberts, M. S., & Grobler, M. (2003). Development of a quality use of medicines coding system to rate clinical pharmacists' medication review recommendations. Pharmacy World and Science, 25(5), 212-217.
DOI
2003 Hung, D., Burczynski, F., Chang, P., Lewis, A., Masci, P., Siebert, G., . . . Roberts, M. S. (2003). Fatty acid binding protein is a major determinant of hepatic pharmacokinetics of palmitate and its metabolites. AJP - Gastrointestinal and Liver Physiology, 284(3), G423-G433.
DOI
2003 Rosado, C., Cross, S., Pugh, W., Roberts, M. S., & Hadgraft, J. (2003). Effect of vehicle pretreatment on the flux, retention, and diffusion of topically applied penetrants in vitro. Pharmaceutical Research.
2003 Cross, S., Thompson, M., & Roberts, M. S. (2003). Transdermal penetration of vascoconstrictors-present understanding and assessment of the human epidermal flux and retention of free nases and ion-pairs. Pharmaceutical Research, 20(2), 270-274.
DOI
2003 Cross, S., Anissimov, Y., Magnusson, B., & Roberts, M. S. (2003). Bovine-serum-albumin-containing receptor phase better predicts transdermal absorption parameters for lipophilic compounds. The Journal of Investigative Dermatology, 120(4), 589-591.
DOI
1996 Rychkov, G. Y., Pusch, M., Astill, D. S. J., Roberts, M. L., Jentsch, T. J., & Bretag, A. H. (1996). Concentration and pH dependence of skeletal muscle chloride channel ClC-1. Journal of Physiology, 497(2), 423-435.
DOI Scopus145 WoS138 Europe PMC120
1983 Roberts, M. S., Rumble, R. H., Wanwimolruk, S., Thomas, D., & Brooks, P. M. (1983). Pharmacokinetics of aspirin and salicylate in elderly subjects and in patients with alcoholic liver disease. European Journal of Clinical Pharmacology, 25(2), 253-261.
DOI Scopus65 Europe PMC49

Year Citation
2022 Benson, H. A. E., & Roberts, M. S. (2022). Challenges and innovations of controlled drug delivery. In H. A. E. Benson (Ed.), Source details - Title: Fundamentals of Drug Delivery (pp. 3-14). US: Wiley.
DOI
2022 Wang, H., Yang, H., Ruan, Q., Roberts, M. S., & Liang, X. (2022). Theranostic nanoparticles for imaging and targeted drug delivery to the liver. In H. A. E. Benson (Ed.), Source details - Title: Fundamentals of Drug Delivery (pp. 311-328). US: Wiley.
DOI
2018 Holmes, A., Thorling, C., Liu, X., Liang, X., Wang, H., Breunig, H. G., . . . Roberts, M. S. (2018). Revealing interaction of dyes and nanomaterials by multiphoton imaging. In K. Karsten (Ed.), Source details - Title: Multiphoton microscopy and fluorescence lifetime imaging: applications in biology and medicine (pp. 345-368). Germany: Walter de Gruyter GmbH.
DOI Scopus3
2017 Liu, X., Wang, H., Liang, X., & Roberts, M. S. (2017). Hepatic metabolism in liver health and disease. In Source details - Title: Liver pathophysiology: therapies and antioxidants (pp. 391-400). UK: Academic Press.
DOI Scopus50
2017 Leite Silva, V. R., Grice, J. E., Mohammed, Y., Moghimi, H. R., & Roberts, M. S. (2017). The influence of emollients on dermal and transdermal drug delivery. In Source details - Title: Percutaneous Penetration Enhancers Drug Penetration Into/Through the Skin: Methodology and General Considerations (pp. 77-93). Germany: Springer.
DOI
2017 Mohammed, Y. H., Moghimi, H. R., Yousef, S. A., Chandrasekaran, N. C., Bibi, C. R., Sukumar, S. C., . . . Roberts, M. S. (2017). Efficacy, safety and targets in topical and transdermal active and excipient delivery. In Source details - Title: Percutaneous Penetration Enhancers Drug Penetration Into/Through the Skin: Methodology and General Considerations (pp. 369-391). Germany: Springer.
DOI
2017 Grice, J. E., Moghimi, H. R., Ryan, E., Zhang, Q., Haridass, I., Mohammed, Y., & Roberts, M. S. (2017). Non-formulation parameters that affect penetrant-skin-vehicle interactions and percutaneous absorption. In Source details - Title: Percutaneous Penetration Enhancers Drug Penetration Into/Through the Skin: Methodology and General Considerations (pp. 45-75). Germany: Springer.
DOI
2017 Pastore, M. N., & Roberts, M. S. (2017). Selection of topically applied chemical candidates: Transdermal drug delivery systems. In K. Sugibayashi (Ed.), Source details - Title: Skin permeation and disposition of therapeutic and cosmeceutical compounds (pp. 251-262). Japan: Springer Japan KK.
DOI
2017 Liang, X., Wang, H., Liu, X., Grice, J., Xu, Z. P., & Roberts, M. (2017). Related topic: safety evaluation of nanomaterials. In K. Sugibayashi (Ed.), Source details - Title: Skin permeation and disposition of therapeutic and cosmeceutical compounds (pp. 313-322). Japan: Springer.
DOI Scopus1
2016 Benson, H. A. E., Mohammed, Y., Grice, J. E., & Roberts, M. S. (2016). Formulation effects on topical nanoparticle penetration. In M. R. Hamblin, P. Avci, & T. W. Prow (Eds.), Source details - Title: Nanoscience in dermatology (pp. 115-126). UK: Academic Press.
DOI
2016 Ryan, E., Grice, J. E., & Roberts, M. S. (2016). Nanotechnology for topical and transdermal drug delivery and targeting. In J. L. Arias (Ed.), Source details - Title: Nanotechnology and drug delivery, volume two: nano-engineering strategies and nanomedicines against severe diseases (pp. 75-101). US: CRC Press.
DOI
2016 Thorling, C. A., Holmes, A., Studier, H., Liu, D., Liang, X., & Roberts, M. S. (2016). Multiphoton and fluorescence lifetime imaging microscopy in studying nanoparticle pharmacokinetics in skin and liver. In S. G. Stanciu (Ed.), Source details - Title: Micro and nanotechnologies for biotechnology (pp. 107-123). Croatia: InTech.
DOI
2015 Kuswahyuning, R., Grice, J. E., Moghimi, H. R., & Roberts, M. S. (2015). Formulation effects in percutaneous absorption. In N. Dragicevic, & H. I. Maibach (Eds.), Source details - Title: Percutaneous penetration enhancers chemical methods in penetration enhancement : drug manipulation strategies and vehicle effects (pp. 109-134). Berlin: Springer.
DOI
2015 Sanchez, W. Y., Pastore, M., Haridass, I. N., König, K., Becker, W., & Roberts, M. S. (2015). Fluorescence lifetime imaging of the skin. In W. Becker (Ed.), Source details - Title: Advanced time-correlated single photon counting applications (pp. 457-508). Switzerland: Springer.
DOI
2014 Anissimov, Y. G., & Roberts, M. S. (2014). Mathematical models for topical and transdermal drug products. In S. Shah, V. P, M. Maibach, H. I, J. Jenner, & J. J (Eds.), Source details - Title: Topical drug bioavailability, bioequivalence, and penetration (2ed ed., pp. 249-298). United States: Springer.
DOI
2014 Sanchez, W. Y., Song, Z., Becker, W., Koenig, K., & Roberts, M. S. (2014). Fluorescence lifetime imaging for diagnostic and therapeutic intravital microscopy. In R. Weigert (Ed.), Source details - Title: Advances in intravital microscopy (pp. 371-418). US: Springer.
DOI Scopus3
2011 Grice, J. E., Prow, T. W., Kendall, M. A. F., & Roberts, M. S. (2011). Electrical and physical methods of skin penetration enhancement. In H. A. E. Benson, & A. C. Watkinson (Eds.), Source details - Title: Topical and transdermal drug delivery: principles and practice (pp. 43-66). US: Wiley.
DOI
2011 Wu, Y. T., Anissimov, Y. G., & Roberts, M. S. (2011). Introduction to dermatokinetics. In S. N. Murthy (Ed.), Source details - Title: Dermatokinetics of therapeutic agents (pp. 1-24). US: CRC Press.
2011 Geusens, B., Mollet, I., Anderson, C. D., Terras, S., Roberts, M. S., & Lambert, J. (2011). Changes in skin immunity with age and disease. In N. Dayan, & P. W. Wertz (Eds.), Source details - Title: Innate Immune System of Skin and Oral Mucosa: Properties and Impact in Pharmaceutics, Cosmetics, and Personal Care Products (pp. 217-258). US: Wiley-Blackwell.
DOI
2008 Dancik, Y., Jepps, O., & Roberts, M. S. (2008). Beyond stratum corneum. In Source details - Title: Dermal absorption and toxicity assessment (2 ed., pp. 209-250). New York: Informa Healthcare.
2008 Kanikkannan, N., Bonner, M., Singh, J., & Roberts, M. (2008). Iontophoresis. In Source details - Title: Dermatologic, cosmeceutic, and cosmetic development: therapeutic and novel approaches (pp. 517-535). New York: Informa healthcare.
2008 Whitehouse, M., Sarkar, M., & Roberts, M. (2008). Drugs for pain and inflammation. In Source details - Title: Dermatologic, cosmeceutic, and cosmetic development: therapeutic and novel approaches (pp. 215-241). New York: Informa.
2008 Roberts, M. S., Gierden, A., Riviere, J., & Monteriro Riviere, N. (2008). Solvent and vehicle effects on the skin. In Source details - Title: Dermal absorption and toxicity assessment (2 ed., pp. 433-447). USA: Informa Healthcare.
2008 Dancik, Y., Jepps, O., & Roberts, M. S. (2008). Physiologically based pharmacokinetics and pharmacodynamics of skin. In Source details - Title: Dermal absorption and toxicity assessment (2 ed., pp. 179-207). New York: Informa Healthcare.
2008 Roberts, M., Bouwstra, J., Pirot, F., & Falson, F. O. (2008). Skin hydration- a key determinant in topical absorption. In Source details - Title: Dermatologic, cosmeceutic, and cosmetic development: therapeutic and novel approaches (pp. 115-128). New York: Informa.
2008 Roberts, M. S., & Walters, K. (2008). Human skin morphology and dermal absorption. In Source details - Title: Dermal absorption and toxicity assessment (2 ed., pp. 1-15). New York: Informa Healthcare.
2008 Roberts, M., & Walters, K. (2008). Skin structure, pharmaceuticals, cosmetics, and the efficacy of topically applied agents. In Source details - Title: Dermatologic, cosmeceutic, and cosmetic development: therapeutic and novel approaches (pp. 1-10). New York: Informa.
2006 Cross, S., & Roberts, M. S. (2006). Dermal blood flow, lymphatics, and binding as determinants of topical absorption, clearance, and distribution.. In M. Roberts, & K. A. Walters (Eds.), Source details - Title: Dermal Absorption Models in Toxicology and Pharmacology (177 ed., pp. 251-281). Boca Raton, FL: Taylor & Francis.
2005 Roberts, M. S., & Anissimov, Y. (2005). Mathematical models in percutaneous absorption. In R. L. Bronaugh, & H. Maibach (Eds.), Source details - Title: Percutaneous Absorption (4 ed., pp. 1-44). Marcel Dekker.

Year Citation
2020 Roberts, M. S., Barkauskas, D. S., Wang, H., Liu, X., Studier, H., Pastore, M. N., . . . Liang, X. (2020). Multiphoton and FLIM imaging in quantifying ex vivo and in vivo body organ kinetics of solutes. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE Vol. 11244 (pp. 14 pages). US: SPIE.
DOI Scopus2 WoS2
2016 Thorling, C. A., Studier, H., Crawford, D., & Roberts, M. S. (2016). Using multiphoton fluorescence lifetime imaging to characterize liver damage and fluorescein disposition in liver in vivo. In Progress in Biomedical Optics and Imaging Vol. 9712 (pp. 1-12). US: SPIE.
DOI
2016 Liang, X., Wang, H., Liu, X., & Roberts, M. (2016). Quantitative optical imaging of paracetamol-induced metabolism changes in the liver. In Proceedings of SPIE Vol. 10013 (pp. 1-4). US: SPIE.
DOI Scopus1
2016 Wang, H., Jayachandran, A., Gravot, G., Liang, X., Thorling, C. A., Zhang, R., . . . Roberts, M. S. (2016). In vivo quantitative visualization of hypochlorous acid in the liver using a novel selective two-photon fluorescent probe. In Proceedings of SPIE - International Society for Optical Engineering Vol. 10013 (pp. 3 pages). US: SPIE.
DOI
2016 Thorling (Thompson), C., Wang, H., Liu, X., Liang, X., Crawford, D. H. G., & Roberts, M. S. (2016). Non-invasive assessment of the liver using imaging. In Proceedings of SPIE Vol. 10013 (pp. 1-5). US: SPIE.
DOI
2016 Liu, X., Liang, X., Wang, H., Roberts, D. M., & Roberts, M. S. (2016). Multiphoton imaging for assessing renal disposition in acute kidney injury. In Proceedings of SPIE Vol. 10013 (pp. 1-4). US: SPIE.
DOI
2008 Roberts, M. S. (2008). Quantum Dots.. In 7th International Conference and Workshop, Biological Barriers and Nanomedicine- Advanced Drug Delivery and Predictive non vivo Testing Technologies.
2008 Prow, T. W., Chen, X., Crichton, M., Tiwari, Y., Gradassi, F., Raphelli, K., . . . Kendall, M. A. F. (2008). Targeted epidermal delivery of vaccines from coated micro-nanoprojection patches. In 2008 International Conference on Nanoscience and Nanotechnology, ICONN 2008 (pp. 125-128). US: IEEE.
DOI
2007 Roberts, M. S. (2007). Dermal absorption of nanoparticles. In ASCEPT 41st Annual Scientific Meeting of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists. Adelaide, Australia.
2007 Roberts, M. S. (2007). Seeking to improve therapeutic outcomes through research. In ASCEPT 41st Annual Scientific Meeting of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists. Adelaide, Australia.
  • Addressing potentially life-threatening ketoacidosis associated with key antidiabetic medicines, The Hospital Research Foundation, 01/01/2021 - 31/12/2023

  • Investigation of the pharmacokinetics and pharmacodynamics of per-and polyfluoroalkyl substances (PFAS), Environment Protection Authority of Victoria, 01/01/2020 - 31/03/2023

  • Priming cancer for radiotherapy, Tour de Cure Ltd, 01/01/2020 - 30/09/2022

  • Improving therapeutic and toxicological outcomes, NHMRC - Research Fellowship, 01/01/2016 - 31/12/2021

  • Characterization of critical quality attributes for semisolid topical drug products, US Food and Drug Administration, 09/10/2014 - 31/12/2020

  • Properties of nanomaterials determine their disposal by liver cells, ARC - Discovery Projects, 01/01/2017 - 30/12/2020

  • Physiological based biopharmaceuticals and pharmacokinetics of drug for dermal absorption in humans, US Food and Drug Administration, 10/09/2014 - 28/02/2019

  • An integrated research program in human toxicology to ensure rapid translation of results into practice and regulation, NHMRC - Program Grant, 01/01/2014 - 31/12/2018

  • Minimising treatment related toxicities in vulnerable patients using a pharmacokinetic based approach, NHMRC - Program Grant, 01/01/2018 - 31/12/2018

  • Optimizing sample preparation for analysis for Toxicokinetic and Toxicodynamic assessment, storage and tracking following Poison Exposures, NHMRC - Program Grant, 01/11/2016 - 31/12/2018

  • Closing the data gap: High throughput screening of nanoparticle toxicity, ARC - Discovery Projects, 01/01/2015 - 01/10/2018

  • Nanotechnology based delivery and response systems CPP28, Collaboration Pathways Program (DSD), 01/05/2014 - 30/06/2017

  • Refining regulatory toxicology through the integration of human clinical toxicology and mechanistic findings, Central Adelaide Local Health Network Incorporated, 04/07/2016 - 28/02/2017

  • Clinical toxicology of various consumer products and poisons after dermal exposure, Central Adelaide Local Health Network Incorporated, 04/07/2016 - 21/02/2017

Date Role Research Topic Program Degree Type Student Load Student Name
2022 Co-Supervisor - Doctor of Philosophy Doctorate Full Time Mr Joshua Dalton

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