Mr Xiaolin Cui
I have worked on various engineering related projects from chemical engineering to biomedical engineering. As a result, I have fresh eyes to identity and solve problems from different angles. I am specialises in medical science, chemical engineering, process engineering, pharmaceutical engineering, polymer science, life science and material engineering. And I has relevant experience of commercial projects and fundamental research commercialisation. My research interests include: tissue engineering, biomaterial, regeneration medicine, cancer cell, biomedical engineering, life science and polymer engineering.
Polymeric biomaterials for tissue engineering: Developed a novel thermally sensitive polymeric materials to work as scaffold for multicellular spheroids culture which has the commercial value.
The impact of micro-environment on tumour spheroids formation: Through copolymerisation technique to tune the structure of polymer to improve materials’ biocompatibility
Tumour spheroids culture on polymeric based micro-fluidics: Developed a novel approach to culture the tumour spheroids inside of microgel-droplets.
Culture colonic crypts on polymeric biomaterials: Conducting serial experiments to explore the possibility of culture colonic crypts (organoid) in thermal reversible microgel network, and also explored how environmental stiffness influences organoid proliferation. Through modifying ECM-protein combined microgel to establish more efficiency approach to culture colonic crypts.
Thermal-sensitive polymeric scaffold for cardiac derived stem cell culture: Optimised the best microgel network for cardiac derived Stem cell culture. Established the best micro-environment for CDC growth. And explored the impact of different charged environment (negative, neutral, positive charge) on stem cells proliferation and functionality.
Thermal-sensitive microgels network for heart regeneration: Conducted an inflammation experiment to prove the safety of injecting microgels. Established a method of treating myocardial infarction using microgels combined with cardiac stem cell. Found a new way to provide foreign cell isolation from immune system rejection.
Displacement efficiency: Established a method to study displacement efficiency of viscous-plastic fluids flow through eccentric annulus. This project was collaborated with Halliburton to understand the pressure drop and flow profile during the process of building oil wells. Using anysis (Fluent) and matlab to simulate the single phase of fluid through annulus to understand the pressure drop when oil flow pipelines.
|2016 - 2016||Visiting Researcher||South Australian Health and Medical Research Institute|
|2015 - 2016||Visiting Scholar||North Carolina State University|
|2014 - 2016||Lab manager and safety officer for pharmaceutical lab||The University of Adelaide|
|2012 - 2012||Research associate||The Univeristy of Adelaide|
|2009 - 2009||Project Engineer||China National Petroleum Corporation (China)|
|2008 - 2008||Intern Egnineer||China National Petroleum Corporation (China)|
|Chinese (Mandarin)||Can read, write, speak, understand spoken and peer review|
|English||Can read, write, speak, understand spoken and peer review|
|2013||The University of Adelaide||Australia||PhD|
|2010 - 2012||The University of Adelaide||Australia||Master|
|2005 - 2009||Dalian University of Technology||China||Bachelor|
|Professional chemical engineer||Engineer Australia||Australia|
|2016||Cui,X, Liu,Y, Hartanto,Y, Bi,J, Dai,S, Zhang,H, 2016, Multicellular Spheroids Formation and Recovery in Microfluidics-generated Thermoresponsive Microgel Droplets, Colloids and Interface Science Communications, 14, 4-7 10.1016/j.colcom.2016.09.001|
|2016||Liu,Y, Wang,ZJ, Li,L, Cui,X, Chu,J, Zhang,SL, Zhuang,YP, 2016, On-line monitoring of the aggregate size distribution of Carthamus tinctorius L. cells with multi-frequency capacitance measurements, RSC Advances, 6, 92, 89764-89769 10.1039/c6ra13527g|
|2016||Cui,X, Dini,S, Dai,S, Bi,J, Binder,BJ, Green,JEF, Zhang,H, 2016, A mechanistic study on tumour spheroid formation in thermosensitive hydrogels: Experiments and mathematical modelling, RSC Advances, 6, 77, 73282-73291 10.1039/c6ra11699j|
|2016||Hartanto,Y, Zargar,M, Cui,X, Shen,Y, Jin,B, Dai,S, 2016, Thermoresponsive cationic copolymer microgels as high performance draw agents in forward osmosis desalination, Journal of Membrane Science, 518, 273-281 10.1016/j.memsci.2016.07.018|
|2016||Yan,L, Cui,X, Harada,T, Lincoln,SF, Dai,S, Kee,TW, 2016, Generation of fluorescent and stable conjugated polymer nanoparticles with hydrophobically modified poly(acrylate)s, Macromolecules, 49, 22, 8530-8539 10.1021/acs.macromol.6b02002|
|2015||Cui,X, Bi,J, Dai,S, Ye,H, 2015, Single-cell analysis for bioprocessing, Engineering in Life Sciences, 15, 6, 582-592 10.1002/elsc.201400155|