Rebecca Harper

Rebecca Harper
Adelaide Medical School
Faculty of Health and Medical Sciences

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Rebecca Harper

Appointments

Date Position Institution name
2017 Adjunct Lecturer The University of Adelaide
2016 Post-doctoral Research Scientist Royal Adelaide Hospital

Awards and Achievements

Date Type Title Institution Name Amount
2017 Doctoral Research Medal University of Adelaide
2016 Dean’s Commendation for Doctoral Thesis Excellence University of Adelaide
2015 South Australia/ NT Branch Young Investigator of the Year
2015 Asia Pacific Society of Respirology Young Investigator Award
2015 American Thoracic Society Abstract Scholarship
2015 Ann Woolcock Young Investigator of the Year Thoracic Society of Australia and New Zealand
2013 Dawes Top-Up Scholarship 2013 Royal Adelaide Hospital
2012 Australian Postgraduate Award
2012 Australian Postgraduate Award
2012 Lions Medical Research Foundation Top-up Scholarship
2011 Highest Honours Grade, School of Medicine
2011 Scicchitano Award

Education

Date Institution name Country Title
University of Adelaide Australia Doctor or Philosophy
The Australian National University Australia Bachelor of Arts/ Bachelor of Science
University of Adelaide Australia Honours Degree of Bachelor of Health Sciences

Journals

Date Citation
2016 Harper,RL, Reynolds,AM, Bonder,CS, Reynolds,PN, 2016, BMPR2 gene therapy for PAH acts via Smad and non-Smad signalling, Respirology, 21, 4, 727-733 10.1111/resp.12729
2016 Feng,F, Harper,RL, Reynolds,PN, 2016, BMPR2 gene delivery reduces mutation-related PAH and counteracts TGF-β-mediated pulmonary cell signalling, Respirology, 21, 3, 526-532 10.1111/resp.12712

Conference Papers

Date Citation
2017 Harper,RL, Cockshell,M, Bonder,CS, Reynolds,PN, 2017, Isolation of exosomes and analysis of their surface markers from PAH peripheral blood derived Endothelial Progenitor Cells, Australasian Extracellular Vesicle Conference, Lorne, Victoria
2016 Harper,RL, Bonder,CS, Reynolds,PN, 2016, BMPR2 Augmented EPC Delivery in a Rat Monocrotaline Induced PAH Model Alters Smad Signalling Profiles, American Thoracic Society Annual Scientific Meeting, San Francisco
2016 Harper,RL, Ward,R, Bonder,CS, Reynolds,PN, 2016, Smad signalling profiles are altered following BMPR2 augmented EPC delivery in a rat Monocrotaline induced PAH model, Thoracic Society of Australia and New Zealand Annual Scientific Meeting, Perth, WA
2016 Harper,RL, Ward,R, Bonder,CS, Reynolds,PN, 2016, Vascular Remodelling is Reversed Following BMPR2 modified Endothelial Progenitor Cell Therapy in a MCT-induced PAH Rat Model, European Respiratory Society Annual Scientific Meeting, London, UK
2015 Harper,RL, Reynolds,PN, 2015, BMPR2 Replacement Therapy via In Situ Gene Delivery or Engineered Endothelial Cells Alleviates PAH in a Rat Model, American Society of Gene and Cell Therapy Annual Scientific Meeting, New Orleans, LO, US
2015 Harper,RL, Bonder,CS, Reynolds,PN, 2015, Up-regulation of BMPR2 in Rat Derived Endothelial Progenitor Cells Leads to the Attenuation of PAH in a MCT Rat Model, American Thoracic Society Annual Scientific Meeting, Denver, CO, US
2015 Harper,RL, Ward,R, Bonder,CS, Reynolds,PN, 2015, Smad and Non Smad Signalling in PAH Following BMPR2 Gene Delivery, American Thoracic Society Annual Scientific Meeting, Denver, CO, US
2014 Harper,RL, Reynolds,PN, 2014, BMPR2 upregulation via in situ gene delivery or via engineered endothelial progenitor cells alleviates pulmonary arterial hypertension (PAH) in a rat model, Thoracic Society of Australia and New Zealand Annual Scientific Meeting, Gold Coast, QLD
2014 Harper,RL, Bonder,CS, Reynolds,PN, 2014, Isolation and Characterisation of a Defined Populations of Endothelial Progenitor Cells from the Left Ventricle: A Pilot Study, Thoracic Society of Australia and New Zealand Annual Scientific Meeting, Adelaide, SA
2012 Harper,RL, Reynolds,AM, Reynolds,PN, 2012, BMPR2 Gene Delivery Shifts Intracellular Smad Activation Profile,“, European Respiratory Society Annual Congress, Vienna, Austria
2012 Harper,RL, Reynolds,AM, Reynolds,PN, 2012, Changes in Smad Signalling Leads To Amelioration of PAH Following Gene Delivery of Bone Morphogenetic Protein Receptor Type 2, American Thoracic Society Annual Scientific Meeting, San Francisco, CA, US

Conference Items

Date Citation
2014 Harper,RL, Reynolds,PN, 2014, Identification Of Novel Cellular Signalling Pathways Following Gene Delivery Of Bone Morphogenetic Protein Receptor Type-2: A Microarray Study
2014 Harper,RL, Reynolds,PN, 2014, Impact of BMPR2 therapy on downstream cell signalling in a PAH model: a microarray study, Thoracic Society of Australia and New Zealand Annual Scientific Meeting, Adelaide, SA 10.1111/resp.12262_9

Theses

Date Citation
2016 Harper,RL; 2016; Gene therapy for Pulmonary Arterial Hypertension with Bone Morphogenetic Protein Receptor Type-2 modulation via engineered endothelial progenitor cells or a targeted Adeno-viral construct: changes in Smad and non-Smad signalling contributed to amelioration of disease

2016 RAH Near Miss Grant                                                                                                                                  $57,205

2015 RAH Research Committee, Clinical Project Grant                                                                                          $50,000

2012 RAH Research Committee, Clinical Project Grant                                                                                          $15,000

Memberships

Date Role Membership Country
2012 Member Golden Key Society

Committee Memberships

Date Role Committee Institution Country
2017 Member AHMS Floor Management Committee University of Adelaide
2016 Representative Local Organising Committee for the 2018 Thoracic Society of Australia and New Zealand Annual Scientific Meeting
2015 Member Wet Laboratory Organising Group University of Adelaide
2015 Member AHMS Animal Users Group University of Adelaide
2013 Representative Local Organising Committee for 2014 Thoracic Society of Australia and New Zealand Annual Scientific Meeting

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