John Horowitz
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.
Professor John Horowitz is a Professor of Cardiology at the University of Adelaide, and Director of Cardiology and Clinical Pharmacology at The Queen Elizabeth Hospital (TQEH). He completed his undergraduate studies in Adelaide, and his postgraduate training in Melbourne and Boston, taking up his current position in 1988.
Project 1. Coronary artery spasm
The research group has recently found that coronary artery spasm, a common cause of cardiac crises, is due to interactions between activated platelets and the vascular surface of the coronary blood vessels, with poor vascular and platelet responsiveness to nitric oxide. We have preliminary data on the underlying mechanisms whereby coronary spasm presents with episodic crises, and wish to validate these pilot data, simultaneously turning the information into the bases for new therapeutic options for these patients, and also possibly for other patients with angina.
Available for Honours, Masters and PhD students
Location: QEH/BHI.
Start: Semester 1 2020
Special requirements: Vaccination required
Project 2 : Preventing heart damage during cancer chemotherapy
The improved results for cancer chemotherapy come at the price of an increased risk of late heart failure. The project will evaluate means of protecting the heart during chemotherapy, by identifying the chemical cause of the damage and neutralising its effects on the heart.
Available for Honours, Masters and PhD students
Location: QEH/BHI.
Start: Semester 1 2020
Special requirements: Vaccination required
Project 3: Maximising protective effects of BNP in patients with heart failure
B-type natriuretic peptide (BNP) is theoretically cardioprotective, bu paradoxically does not work in patients with heart failure. We have identified the cause of this problem, and now wish to develop therapeutic strategies to improve BNP responses, not only in patients with isolated heart failure, but also in those with heart failure secondary to influenza virus infection.
Available for Honours, Masters and PhD students
Location: QEH/BHI.
Start: Semester 1 2020
Special requirements: Vaccination required
Project 4: Variability of anti-aggregatory effects of P2Y12 receptor antagonists: therapeutic adjustments
Clopidogrel and ticagrelor are antagonists at the P2Y12 receptor, which limit platlet aggregation: they are used mainly to prevent thrombosis of coronary stents. However, responses vary substantially. We intend to develop regimens for individual patients who, on theoretical grounds, are at risk for either bleeding or thrombosis when placed on theoretically "standard" treatment regimens.
Available for Honours, Masters and PhD students
Location: QEH/BHI.
Start: Semester 1 2020
Special requirements: Vaccination required
Project 5: Improving outcomes after takotsubo (broken heart) syndrome
Takotsubo syndrome (TTS) affects many ageing patients, especially women, and is often mistaken for heart attacks. We are trying to improve diagnosis, emergency and long-term treatment of TTS, using both clinical and basic investigation strategies.
Available for Honours, Masters and PhD students
Location: QEH/BHI.
Start: Semester 1 2020
Special requirements: Vaccination required
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Appointments
Date Position Institution name 2018 - ongoing Emeritus Professor University of Adelaide -
Research Interests
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Journals
Year Citation 2024 Horowitz, J. D., & Rogers, N. M. (2024). Oral anticoagulation for hemodialysis patients with atrial fibrillation: The therapeutic conundrum remains. Trends in Cardiovascular Medicine, S1050-1738(24)00006-9.
2024 Liu, S., Lawrie, I. A. J., Rabia, B., & Horowitz, J. D. (2024). Impairment of Vascular Homeostasis in Acute Heart Failure: Enter the Monocyte?. Cardiovascular Drugs and Therapy, 5 pages.
2023 Horowitz, J. D., & Surikow, S. Y. (2023). Understanding Takotsubo syndrome: first evaluate your mouse model. American Journal of Physiology - Heart and Circulatory Physiology, 324(5), H630-H632.
2023 Iyngkaran, P., Hanna, F., Andrew, S., Horowitz, J. D., Battersby, M., & De Courten, M. P. (2023). Comparison of short and long forms of the Flinders program of chronic disease SELF-management for participants starting SGLT-2 inhibitors for congestive heart failure (SELFMAN-HF): protocol for a prospective, observational study. Frontiers in Medicine, 10, 11 pages.
2023 Muminovic, A., Chirkov, Y. Y., & Horowitz, J. D. (2023). Effects of Soluble Guanylate Cyclase Stimulators and Activators on Anti-Aggregatory Signalling in Patients with Coronary Artery Spasm. International Journal of Molecular Sciences, 24(11), 11 pages.
2023 Kei, C. Y., Singh, K., Dautov, R. F., Nguyen, T. H., Chirkov, Y. Y., & Horowitz, J. D. (2023). Coronary “Microvascular Dysfunction”: Evolving Understanding of Pathophysiology, Clinical Implications, and Potential Therapeutics. International Journal of Molecular Sciences, 24(14), 11287.
Scopus6 WoS2 Europe PMC32023 Kelly, C. J., Chu, M., Untaru, R., Assadi-Khansari, B., Chen, D., Croft, A. J., . . . Ngo, D. T. M. (2023). Association of Circulating Plasma Secreted Frizzled-Related Protein 5 (Sfrp5) Levels with Cardiac Function. Journal of Cardiovascular Development and Disease, 10(7), 9 pages.
Scopus1 WoS12023 De Filippo, O., Cammann, V. L., Pancotti, C., Di Vece, D., Silverio, A., Schweiger, V., . . . Budnik, M. (2023). Machine learning-based prediction of in-hospital death for patients with takotsubo syndrome: The InterTAK-ML model. European Journal of Heart Failure, 25(12), 2299-2311.
Scopus2 WoS22023 Ong, G. J., Sellers, A., Mahadavan, G., Nguyen, T. H., Worthley, M. I., Chew, D. P., & Horowitz, J. D. (2023). ‘Bushfire Season’ in Australia: Determinants of Increases in Risk of Acute Coronary Syndromes and Takotsubo Syndrome. American Journal of Medicine, 136(1), 88-95.
2023 Iyngkaran, P., Hespe, C., Hanna, F., Horowitz, J. D., Battersby, M., Nelson, C., . . . de Courten, M. P. (2023). The Wider Considerations in Closing Chronic Disease Gaps – Focus on Heart Failure and Implementation. Current Cardiology Reviews, 19(2), 14 pages.
Europe PMC12022 Aulin, J., Hijazi, Z., Lindbäck, J., Alexander, J. H., Gersh, B. J., Granger, C. B., . . . Wallentin, L. (2022). Biomarkers and heart failure events in patients with atrial fibrillation in the ARISTOTLE trial evaluated by a multi-state model. American Heart Journal, 251, 13-24.
Scopus5 WoS6 Europe PMC32022 Iyngkaran, P., Calder, R., Nelson, C., Lowthian, J., Hespe, C., Horowitz, J., & de Courten, M. P. (2022). Opportunities to link Heart Failure Guidelines and chronic disease management—preliminary considerations. Reviews in Cardiovascular Medicine, 23(4), 9 pages.
2022 Girolamo, O. C., Surikow, S. Y., Ong, G. J., Nguyen, T. H., Kucia, A. M., Chirkov, Y. Y., & Horowitz, J. D. (2022). TakoTsubo Syndrome: First an Acute Coronary Vasculitis and Then Prolonged Myocarditis?. Reviews in Cardiovascular Medicine, 23(5), 9 pages.
Scopus3 WoS32022 Chirkov, Y. Y., Nguyen, T. H., & Horowitz, J. D. (2022). Impairment of Anti-Aggregatory Responses to Nitric Oxide and Prostacyclin: Mechanisms and Clinical Implications in Cardiovascular Disease. International Journal of Molecular Sciences, 23(3), 21 pages.
Scopus13 WoS10 Europe PMC102022 Iyngkaran, P., Hanna, F., Horowitz, J. D., & de Courten, M. P. (2022). Contextualising evidence based medicine in determining the key root for translational effectiveness for chronic disease self-management and heart failure. Reviews in Cardiovascular Medicine, 23(1), 9 pages.
Scopus1 WoS1 Europe PMC12022 Dhakal, B., Li, C. M. Y., Li, R., Yeo, K., Wright, J. A., Gieniec, K. A., . . . Fenix, K. (2022). The Antianginal Drug Perhexiline Displays Cytotoxicity against Colorectal Cancer Cells In Vitro: A Potential for Drug Repurposing. Cancers, 14(4), 16 pages.
Scopus9 WoS7 Europe PMC82022 Velagic, A., Li, J. C., Qin, C. X., Li, M., Deo, M., Marshall, S. A., . . . Ritchie, R. H. (2022). Cardioprotective Actions of Nitroxyl Donor Angeli's Salt are Preserved in the Diabetic Heart and Vasculature in the Face of Nitric Oxide Resistance. British Journal of Pharmacology, 179(16), 4117-4135.
Scopus3 WoS2 Europe PMC22022 Laumer, F., Di Vece, D., Cammann, V. L., Würdinger, M., Petkova, V., Schönberger, M., . . . Templin, C. (2022). Assessment of Artificial Intelligence in Echocardiography Diagnostics in Differentiating Takotsubo Syndrome from Myocardial Infarction. JAMA Cardiology, 7(5), 494-503.
Scopus19 WoS13 Europe PMC82022 Tully, P. J., Turnbull, D. A., Horowitz, J. D., Beltrame, J. F., Baune, B. T., Sauer-Zavala, S., . . . Wittert, G. A. (2022). Transdiagnostic Cognitive-Behavioral Therapy for Depression and Anxiety Disorders in Cardiovascular Disease Patients: Results From the CHAMPS Pilot-Feasibility Trial. Frontiers in Psychiatry, 13, 1-12.
Scopus5 WoS2 Europe PMC22022 Ong, G. J., Nguyen, T. H., Surikow, S. Y., & Horowitz, J. D. (2022). Risk factors for a broken heart: understanding drug-induced causes for Takotsubo syndrome and pharmacological treatment options. Expert Review of Clinical Pharmacology, 15(9), 1017-1025.
2022 Horowitz, J. D., & Nguyen, T. H. (2022). Takotsubo Syndrome: Severe Early Coronary Vasculitis Predicts Slow Recovery. JACC: Cardiovascular Imaging, 15(10), 1796-1798.
Europe PMC12022 Chong, C. -R., Liu, S., Imam, H., Heresztyn, T., Sallustio, B. C., Chirkov, Y. Y., & Horowitz, J. D. (2022). Perhexiline Therapy in Patients with Type 2 Diabetes: Incremental Insulin Resistance despite Potentiation of Nitric Oxide Signaling. Biomedicines, 10(10), 2381-1-2381-10.
2022 Ong, G. J., & Horowitz, J. D. (2022). Ambulance ramping and patients with cardiac-type symptoms: understanding the unloading queue. Medical Journal of Australia, 217(5), 238-239.
2022 De Caterina, R., Patti, G., Westerbergh, J., Horowitz, J., Ezekowitz, J. A., Lewis, B. S., . . . Wallentin, L. (2022). Heterogeneity of diabetes as a risk factor for major adverse cardiovascular events in anticoagulated patients with atrial fibrillation: an analysis of the ARISTOTLE trial. European Heart Journal - Cardiovascular Pharmacotherapy, 8(3), 227-235.
Scopus5 WoS6 Europe PMC32022 Imori, Y., Kato, K., Cammann, V. L., Szawan, K. A., Wischnewsky, M., Dreiding, S., . . . Poglajen, G. (2022). Ethnic comparison in takotsubo syndrome: novel insights from the International Takotsubo Registry. Clinical Research in Cardiology, 111(2), 186-196.
Scopus11 WoS8 Europe PMC52021 Ananthakrishna, R., Lee, S. L., Foote, J., Sallustio, B. C., Binda, G., Mangoni, A. A., . . . Selvanayagam, J. B. (2021). Randomized controlled trial of perhexiline on regression of left ventricular hypertrophy in patients with symptomatic hypertrophic cardiomyopathy (RESOLVE-HCM trial). American Heart Journal, 240, 101-113.
Scopus12 WoS9 Europe PMC92021 El-Battrawy, I., Cammann, V. L., Kato, K., Szawan, K. A., Di Vece, D., Rossi, A., . . . Ghadri, J. R. (2021). Impact of atrial fibrillation on outcome in takotsubo syndrome: Data from the international Takotsubo registry. Journal of the American Heart Association, 10(15), 12 pages.
Scopus20 WoS18 Europe PMC132021 Schwartz, G. G., Szarek, M., Bittner, V. A., Diaz, R., Goodman, S. G., Jukema, J. W., . . . Dombrowski, K. (2021). Lipoprotein(a) and Benefit of PCSK9 Inhibition in Patients With Nominally Controlled LDL Cholesterol. Journal of the American College of Cardiology, 78(5), 421-433.
Scopus56 WoS47 Europe PMC212021 Nguyen, T. H., Ong, G. J., & Horowitz, J. D. (2021). Letter by Nguyen et al Regarding Article, "coronary Optical Coherence Tomography and Cardiac Magnetic Resonance Imaging to Determine Underlying Causes of Myocardial Infarction with Nonobstructive Coronary Arteries in Women". Circulation, 144(12), E205.
2021 Nguyen, T. H., Ong, G. J., Girolamo, O. C., De Menezes Caceres’, V., Muminovic, A., Chirkov, Y. Y., & Horowitz, J. D. (2021). Angina due to coronary artery spasm (variant angina): diagnosis and intervention strategies. Expert Review of Cardiovascular Therapy, 19(10), 917-927.
Scopus7 WoS4 Europe PMC52021 Imam, H., Nguyen, T. H., Stafford, I., Liu, S., Heresztyn, T., Chirkov, Y. Y., & Horowitz, J. D. (2021). Impairment of platelet NO signalling in coronary artery spasm: role of hydrogen sulphide. British Journal of Pharmacology, 178(7), 1639-1650.
Scopus11 WoS10 Europe PMC62021 Visvanathan, V., Kucia, A., Reddi, B., & Horowitz, J. (2021). Late development of Takotsubo syndrome following intensive care unit discharge. Netherlands Journal of Critical Care, 29(1), 14-21.
Scopus12021 Kato, K., Cammann, V. L., Napp, L. C., Szawan, K. A., Micek, J., Dreiding, S., . . . Schunkert, H. (2021). Prognostic impact of acute pulmonary triggers in patients with takotsubo syndrome: new insights from the International Takotsubo Registry. ESC Heart Failure, 8(3), 1924-1932.
Scopus6 WoS3 Europe PMC52021 Ong, G. J., Girolamo, O., Stansborough, J., Nguyen, T. H., & Horowitz, J. D. (2021). Incidence and clinical/laboratory correlates of early hypotension in takotsubo syndrome. ESC Heart Failure, 8(3), 2009-2015.
Scopus2 WoS2 Europe PMC12021 Kemp-Harper, B. K., Velagic, A., Paolocci, N., Horowitz, J. D., & Ritchie, R. H. (2021). Cardiovascular Therapeutic Potential of the Redox Siblings, Nitric Oxide (NO•) and Nitroxyl (HNO), in the Setting of Reactive Oxygen Species Dysregulation. Handbook of experimental pharmacology, 264, 311-337.
Scopus9 Europe PMC42021 Ong, G. J., Nguyen, T. H., Kucia, A., Liu, S. -F., Surikow, S. Y., Girolamo, O., . . . Horowitz, J. D. (2021). Takotsubo syndrome: Finally emerging from the shadows?. Heart Lung and Circulation, 30(1), 36-44.
Scopus10 WoS9 Europe PMC42021 Iyngkaran, P., Thomas, M., Horowitz, J. D., Komesaroff, P., Jelinek, M., & Hare, D. L. (2021). Common Comorbidities that Alter Heart Failure Prognosis-Shaping New Thinking for Practice. Current Cardiology Reviews, 17(5), 10 pages.
Scopus3 WoS3 Europe PMC22021 Schwarz, K., Parasuraman, S., Singh, S., Horowitz, J. D., Dawson, D. K., & Frenneaux, M. P. (2021). The unspoken benefit of participation in a clinical trial. Clinical Medicine, Journal of the Royal College of Physicians of London, 21(6), E645-E647.
Scopus2 WoS2 Europe PMC12021 Cammann, V. L., Scheitz, J. F., von Rennenberg, R., Jäncke, L., Nolte, C. H., Szawan, K. A., . . . Budnik, M. (2021). Clinical correlates and prognostic impact of neurologic disorders in Takotsubo syndrome. Scientific Reports, 11(1), 23555.
Scopus14 Europe PMC72021 Nguyen, T. H., Surikow, S. Y., & Horowitz, J. D. (2021). Editorial commentary: Takotsubo Syndrome: A key role for inflammation?. Trends in Cardiovascular Medicine, 31(4), 231-232.
Scopus2 WoS2 Europe PMC12020 Napp, L. C., Cammann, V. L., Jaguszewski, M., Szawan, K. A., Wischnewsky, M., Gili, S., . . . Templin, C. (2020). Coexistence and outcome of coronary artery disease in Takotsubo syndrome.. Eur Heart J, 41(34), 3255-3267.
Scopus48 WoS40 Europe PMC232020 Nguyen, T., Chirkov, Y., Liu, S., Stafford, I., & Horowitz, J. (2020). Increased Rate of Hospitalization With Prinzmetal Angina: What Exactly Is Happening?. American Journal of Medicine, 133(4), e162-e163.
Scopus1 WoS12020 Cammann, V. L., Szawan, K. A., Stähli, B. E., Kato, K., Budnik, M., Wischnewsky, M., . . . Horowitz, J. D. (2020). Age-Related Variations in Takotsubo Syndrome. Journal of the American College of Cardiology, 75(16), 1869-1877.
Scopus40 WoS28 Europe PMC202020 Ong, G. J., Nguyen, T. H., Stansborough, J., Surikow, S. Y., & Horowitz, J. D. (2020). Incremental "Therapeutic" Myocardial Exposure to Catecholamines: Incidence and Impact in Takotsubo Syndrome.. Cardiovasc Drugs Ther, 34(1), 95-100.
Scopus6 WoS6 Europe PMC12020 Iyngkaran, P., Thomas, M. C., Neil, C., Jelinek, M., Cooper, M., Horowitz, J. D., . . . Kaye, D. M. (2020). The Heart Failure with Preserved Ejection Fraction Conundrum—Redefining the Problem and Finding Common Ground?. Current Heart Failure Reports, 17(2), 34-42.
Scopus11 WoS9 Europe PMC82020 D'Ascenzo, F., Gili, S., Bertaina, M., Iannaccone, M., Cammann, V. L., Di Vece, D., . . . Templin, C. (2020). Impact of aspirin on takotsubo syndrome: a propensity score-based analysis of the InterTAK Registry.. European journal of heart failure, 22(6), 330-337.
Scopus28 WoS27 Europe PMC112020 Bittner, V. A., Szarek, M., Aylward, P. E., Bhatt, D. L., Diaz, R., Edelberg, J. M., . . . Ball, E. (2020). Effect of Alirocumab on Lipoprotein(a) and Cardiovascular Risk After Acute Coronary Syndrome. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 75(2), 133-144.
WoS223 Europe PMC1182020 Ntessalen, M., Procter, N. E., Schwarz, K., Loudon, B. L., Minnion, M., Fernandez, B. O., . . . Frenneaux, M. P. (2020). Inorganic nitrate and nitrite supplementation fails to improve skeletal muscle mitochondrial efficiency in mice and humans.. The American journal of clinical nutrition, 111(1), 79-89.
Scopus14 WoS12 Europe PMC62020 Qin, C. X., Anthonisz, J., Leo, C. H., Kahlberg, N., Velagic, A., Li, M., . . . Ritchie, R. H. (2020). Nitric oxide resistance, induced in the myocardium by diabetes, is circumvented by the nitric oxide redox sibling, nitroxyl. Antioxidants and Redox Signaling, 32(1), 60-77.
Scopus20 WoS17 Europe PMC142020 Ong, G. J., Nguyen, T. H., Stansborough, J., Surikow, S., Mahadavan, G., Worthley, M., & Horowitz, J. (2020). The N-AcetylCysteine and RAMipril in Takotsubo Syndrome Trial (NACRAM): Rationale and design of a randomised controlled trial of sequential N-Acetylcysteine and ramipril for the management of Takotsubo Syndrome.. Contemporary clinical trials, 90, 105894.
Scopus15 WoS12 Europe PMC82020 Ding, K. J., Cammann, V. L., Szawan, K. A., Stähli, B. E., Wischnewsky, M., Di Vece, D., . . . Templin, C. (2020). Intraventricular Thrombus Formation and Embolism in Takotsubo Syndrome: Insights From the International Takotsubo Registry.. Arteriosclerosis, thrombosis, and vascular biology, 40(1), 279-287.
Scopus31 WoS30 Europe PMC192020 Horowitz, J. D., & Chong, C. -R. (2020). Matrix metalloproteinase-2 activation: critical to myocardial contractile dysfunction following ischaemia-reperfusion.. Cardiovascular research, 116(5), 876-878.
Scopus3 WoS3 Europe PMC32020 Mannil, M., Kato, K., Manka, R., von Spiczak, J., Peters, B., Cammann, V. L., . . . Templin, C. (2020). Prognostic value of texture analysis from cardiac magnetic resonance imaging in patients with Takotsubo syndrome: a machine learning based proof-of-principle approach. Scientific Reports, 10(1), 9 pages.
Scopus9 WoS8 Europe PMC62020 Nooney, V. B., Hurst, N. L., De Caterina, R., Chirkov, Y. Y., & Horowitz, J. D. (2020). Does high on-treatment platelet aggregability reflect poor individual response to clopidogrel?. Thrombosis Research, 196, 510-515.
Scopus5 WoS5 Europe PMC32020 Velagic, A., Qin, C., Woodman, O. L., Horowitz, J. D., Ritchie, R. H., & Kemp-Harper, B. K. (2020). Nitroxyl: a novel strategy to circumvent diabetes associated impairments in nitric oxide signaling. Frontiers in Pharmacology, 11, 727-1-727-18.
Scopus13 WoS12 Europe PMC92020 Aulin, J., Hijazi, Z., Siegbahn, A., Andersson, U., Alexander, J. H., Connolly, S. J., . . . Oldgren, J. (2020). Serial measurement of interleukin-6 and risk of mortality in anticoagulated patients with atrial fibrillation: Insights from ARISTOTLE and RE-LY trials. Journal of Thrombosis and Haemostasis, 18(9), 2287-2295.
Scopus12 WoS11 Europe PMC62020 Liu, S., Ngo, D., Chirkov, Y., Stansborough, J., Chong, C., & Horowitz, J. D. (2020). Prolonged suppression of the anti-oxidant/anti-inflammatory effects of BNP post-Takotsubo syndrome. ESC Heart Failure, 7(5), 2250-2257.
Scopus1 Europe PMC22019 Roe, M. T., Li, Q. H., Bhatt, D. L., Bittner, V. A., Diaz, R., Goodman, S. G., . . . Zobouyan, I. (2019). Risk Categorization Using New American College of Cardiology/American Heart Association Guidelines for Cholesterol Management and Its Relation to Alirocumab Treatment Following Acute Coronary Syndromes. CIRCULATION, 140(19), 1578-1589.
WoS31 Europe PMC172019 Jurisic, S., Gili, S., Cammann, V. L., Kato, K., Szawan, K. A., D'Ascenzo, F., . . . Templin, C. (2019). Clinical Predictors and Prognostic Impact of Recovery of Wall Motion Abnormalities in Takotsubo Syndrome: Results From the International Takotsubo Registry. Journal of the American Heart Association, 8(21), e011194.
Scopus23 WoS19 Europe PMC102019 White, H. D., Steg, P. G., Szarek, M., Bhatt, D. L., Bittner, V. A., Diaz, R., . . . Ball, E. (2019). Effects of alirocumab on types of myocardial infarction: insights from the ODYSSEY OUTCOMES trial. EUROPEAN HEART JOURNAL, 40(33), 2801-2809.
WoS41 Europe PMC212019 Jukema, J. W., Szarek, M., Zijlstra, L. E., de Silva, H. A., Bhatt, D. L., Bittner, V. A., . . . Zobouyan, I. (2019). Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome ODYSSEY OUTCOMES Trial. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 74(9), 1167-1176.
WoS124 Europe PMC572019 Goodman, S. G., Aylward, P. E., Szarek, M., Chumburidze, V., Bhatt, D. L., Bittner, V. A., . . . Ball, E. (2019). Effects of Alirocumab on Cardiovascular Events After Coronary Bypass Surgery. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 74(9), 1177-1186.
WoS37 Europe PMC142019 Grech, M., Turnbull, D. A., Wittert, G. A., Tully, P. J., & CHAMPS Investigators. (2019). Identifying the internalizing disorder clusters among recently hospitalized cardiovascular disease patients: a receiver operating characteristics study. Frontiers in Psychology, 10, 2829-1-2829-11.
Scopus3 WoS1 Europe PMC12019 Szarek, M., Steg, P. G., DiCenso, D., Bhatt, D. L., Bittner, V. A., Budaj, A., . . . Zobouyan, I. (2019). Alirocumab Reduces Total Hospitalizations and Increases Days Alive and Out of Hospital in the ODYSSEY OUTCOMES Trial. CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES, 12(11), 9 pages.
WoS15 Europe PMC82019 Steg, P. G., Szarek, M., Bhatt, D. L., Bittner, V. A., Bregeault, M. -F., Dalby, A. J., . . . Zobouyan, I. (2019). Effect of Alirocumab on Mortality After Acute Coronary Syndromes An Analysis of the ODYSSEY OUTCOMES Randomized Clinical Trial. CIRCULATION, 140(2), 103-112.
WoS93 Europe PMC352019 Nguyen, T. H., Stansborough, J., Ong, G. J., Surikow, S., Price, T. J., & Horowitz, J. D. (2019). Antecedent cancer in takotsubo syndrome predicts both cardiovascular and long-term mortality. Cardio-Oncology, 5(1), 9 pages.
Scopus9 WoS7 Europe PMC42019 Szarek, M., White, H. D., Schwartz, G. G., Alings, M., Bhatt, D. L., Bittner, V. A., . . . Zobouyan, I. (2019). Alirocumab Reduces Total Nonfatal Cardiovascular and Fatal Events The ODYSSEY OUTCOMES Trial. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 73(4), 387-396.
WoS107 Europe PMC432019 Wischnewsky, M. B., Candreva, A., Bacchi, B., Cammann, V. L., Kato, K., Szawan, K. A., . . . Templin, C. (2019). Prediction of short- and long-term mortality in takotsubo syndrome: the InterTAK Prognostic Score. European Journal of Heart Failure, 21(11), 1469-1472.
Scopus21 WoS15 Europe PMC102019 Ajaero, C. N., Procter, N. E. K., Chirkov, Y., Heresztyn, T., Arstall, M. A., McGavigan, A. D., . . . Horowitz, J. D. (2019). Endothelial dysfunction and glycocalyx shedding in heart failure: insights from patients receiving cardiac resynchronisation therapy. Heart and Vessels, 35(2), 197-206.
Scopus7 WoS6 Europe PMC32019 Cammann, V. L., Sarcon, A., Ding, K. J., Seifert, B., Kato, K., Di Vece, D., . . . Templin, C. (2019). Clinical Features and Outcomes of Patients With Malignancy and Takotsubo Syndrome: Observations From the International Takotsubo Registry. Journal of the American Heart Association, 8(15), 1-13.
Scopus63 WoS50 Europe PMC342019 Imam, H., Nguyen, T. H., De Caterina, R., Nooney, V. B., Chong, C. R., Horowitz, J. D., & Chirkov, Y. Y. (2019). Impaired adenylate cyclase signaling in acute myocardial ischemia: Impact on effectiveness of P2Y<inf>12</inf> receptor antagonists. Thrombosis Research, 181, 92-98.
Scopus6 WoS4 Europe PMC22019 Di Vece, D., Citro, R., Cammann, V. L., Kato, K., Gili, S., Szawan, K. A., . . . Templin, C. (2019). Outcomes Associated With Cardiogenic Shock in Takotsubo Syndrome.. Circulation, 139(3), 413-415.
Scopus67 WoS63 Europe PMC352019 Liu, S., Chirkov, Y. Y., & Horowitz, J. D. (2019). Neutrophil-initiated myocardial inflammation and Its modulation by B-type natriuretic peptide: a potential therapeutic target. International Journal of Molecular Sciences, 20(1), 129-1-129-13.
Scopus5 WoS5 Europe PMC52019 Ajaero, C. N., Ganesan, A., Horowitz, J. D., & McGavigan, A. D. (2019). Electrical remodelling post cardiac resynchronization therapy in patients with ischemic and non-ischemic heart failure. Journal of Electrocardiology, 53, 44-51.
Scopus2 WoS22019 Washam, J. B., Hohnloser, S. H., Lopes, R. D., Wojdyla, D. M., Vinereanu, D., Alexander, J. H., . . . Granger, C. B. (2019). Interacting medication use and the treatment effects of apixaban versus warfarin: results from the ARISTOTLE Trial. Journal of Thrombosis and Thrombolysis, 47(3), 345-352.
Scopus12 WoS11 Europe PMC82019 Iyngkaran, P., Chan, W., Liew, D., Zamani, J., Horowitz, J. D., Jelinek, M., . . . Shaw, J. A. (2019). Risk stratification for coronary artery disease in multi-ethnic populations: Are there broader considerations for cost efficiency?. World journal of methodology, 9(1), 1-19.
Europe PMC52019 Nguyen, T. H., Heresztyn, T., & Horowitz, J. D. (2019). Risk indexation and atrial fibrillation. Aging, 11(6), 1607-1608.
2019 Gili, S., Cammann, V. L., Schlossbauer, S. A., Kato, K., D Ascenzo, F., Di Vece, D., . . . Templin, C. (2019). Cardiac arrest in takotsubo syndrome: Results from the InterTAK Registry. European Heart Journal, 40(26), 2142-2151.
Scopus72 WoS57 Europe PMC312019 Liu, S., & Horowitz, J. D. (2019). Interactions between Influenza and Heart Failure Hospitalizations-Diagnostic and Pathogenetic Issues. JAMA Cardiology, 4(9), 949-950.
Scopus1 WoS1 Europe PMC12019 Ray, K. K., Colhoun, H. M., Szarek, M., Baccara-Dinet, M., Bhatt, D. L., Bittner, V. A., . . . Steg, P. G. (2019). Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY OUTCOMES randomised controlled trial. The Lancet Diabetes and Endocrinology, 7(8), 618-628.
Scopus219 WoS143 Europe PMC962018 Schwartz, G., Steg, P., Szarek, M., Bhatt, D., Bittner, V., Diaz, R., . . . Leone, A. (2018). Alirocumab and cardiovascular outcomes after acute coronary syndrome. New England Journal of Medicine, 379(22), 2097-2107.
Scopus2142 WoS1697 Europe PMC9272018 Bohula, E., Scirica, B., Inzucchi, S., McGuire, D., Keech, A., Smith, S., . . . Savard, D. (2018). Effect of lorcaserin on prevention and remission of type 2 diabetes in overweight and obese patients (CAMELLIA-TIMI 61): a randomised, placebo-controlled trial. The Lancet, 392(10161), 2269-2279.
Scopus66 WoS59 Europe PMC402018 Surikow, S. Y., Nguyen, T. H., Stafford, I., Chapman, M., Chacko, S., Singh, K., . . . Horowitz, J. D. (2018). Nitrosative stress as a modulator of inflammatory change in a model of Takotsubo syndrome. JACC: Basic to Translational Science, 3(2), 213-226.
Scopus47 WoS44 Europe PMC212018 Ghadri, J. R., Wittstein, I. S., Prasad, A., Sharkey, S., Dote, K., Akashi, Y. J., . . . Templin, C. (2018). International Expert Consensus Document on Takotsubo Syndrome (Part II): Diagnostic Workup, Outcome, and Management. European Heart Journal, 39(22), 2047-2062.
Scopus464 WoS420 Europe PMC2662018 Ghadri, J. R., Wittstein, I. S., Prasad, A., Sharkey, S., Dote, K., Akashi, Y. J., . . . Templin, C. (2018). International Expert Consensus Document on Takotsubo Syndrome (Part I): Clinical Characteristics, Diagnostic Criteria, and Pathophysiology. European Heart Journal, 39(22), 2032-2046.
Scopus870 WoS799 Europe PMC5062018 Horowitz, J., De Caterina, R., Heresztyn, T., Alexander, J., Andersson, U., Lopes, R., . . . Wallentin, L. (2018). Asymmetric and symmetric dimethylarginine predict outcomes in patients with atrial fibrillation: an ARISTOTLE substudy. Journal of the American College of Cardiology, 72(7), 721-733.
Scopus31 WoS30 Europe PMC182018 Ghadri, J., Kato, K., Cammann, V., Gili, S., Jurisic, S., Di Vece, D., . . . Templin, C. (2018). Long-Term Prognosis of Patients With Takotsubo Syndrome. Journal of the American College of Cardiology, 72(8), 874-882.
Scopus219 WoS192 Europe PMC1052018 Horowitz, J. D., & Sage, P. R. (2018). Can we improve long-term outcomes postbifurcation stenting by prolonged dual antiplatelet therapy?. Circulation: Cardiovascular Interventions, 11(7), 3 pages.
Scopus1 WoS3 Europe PMC12018 Horowitz, J. D., & Liu, S. (2018). ADAM-15 and glycocalyx shedding: A new perspective on sepsis-related vasomotor dysfunction. Cardiovascular Research, 114(13), 1694-1695.
Scopus3 WoS3 Europe PMC22018 Ajaero, C., Chong, C. -R., Procter, N., Liu, S., Chirkov, Y., Heresztyn, T., . . . Horowitz, J. (2018). Does cardiac resynchronization therapy restore peripheral circulatory homeostasis?. ESC heart failure, 5(1), 129-138.
Scopus1 WoS1 Europe PMC22017 Schwarz, K., Singh, S., Parasuraman, S., Rudd, A., Shepstone, L., Feelisch, M., . . . Frenneaux, M. (2017). Inorganic nitrate in angina study: a randomized double-blind placebo-controlled trial. Journal of the American Heart Association, 6(9), 006478-1-006478-S.
Scopus13 WoS10 Europe PMC52017 Schwarz, K., Ahearn, T., Srinivasan, J., Neil, C. J., Scally, C., Rudd, A., . . . Dawson, D. K. (2017). Author's Reply. Journal of the American Society of Echocardiography, 30(10), 1042.
Scopus12017 Vaduganathan, M., Harrington, R. A., Stone, G. W., Deliargyris, E. N., Steg, P. G., Gibson, C. M., . . . Chandra, P. (2017). Cangrelor With and Without Glycoprotein IIb/IIIa Inhibitors in Patients Undergoing Percutaneous Coronary Intervention. Journal of the American College of Cardiology, 69(2), 176-185.
Scopus48 WoS46 Europe PMC242017 Steeds, R. P., Cowie, M. R., Rana, B. S., Chambers, J. B., Ray, S., Srinivasan, J., . . . Russhard, P. (2017). Report from the Annual Conference of the British Society of Echocardiography, November 2016, Queen Elizabeth II Conference Centre, London. ECHO RESEARCH AND PRACTICE, 4(3), M1-M16.
2017 Amarasekera, A., Assadi-Khansari, B., Liu, S., Black, M., Dymmott, G., Rogers, N., . . . Ngo, D. (2017). Vitamin D supplementation lowers thrombospondin-1 levels and blood pressure in healthy adults. PLoS ONE, 12(5), e0174435-1-e0174435-14.
Scopus11 WoS8 Europe PMC82017 Scuffham, P., Ball, J., Horowitz, J., Wong, C., Newton, P., Macdonald, P., . . . Stewart, S. (2017). Standard vs. intensified management of heart failure to reduce healthcare costs: results of a multicentre, randomized controlled trial. European Heart Journal, 38(30), 2340-2348.
Scopus23 WoS17 Europe PMC92017 Pasupathy, S., Tavella, R., Grover, S., Raman, B., Procter, N. E. K., Du, Y. T., . . . Beltrame, J. F. (2017). Early use of N-acetylcysteine with nitrate therapy in patients undergoing primary percutaneous coronary intervention for ST-segment-elevation myocardial infarction reduces myocardial infarct size (the NACIAM trial [N-acetylcysteine in acute myocardial infarction]). Circulation, 136(10), 894-903.
Scopus106 WoS90 Europe PMC602017 Schwarz, K., Ahearn, T., Srinivasan, J., Neil, C., Scally, C., Rudd, A., . . . Dawson, D. (2017). Alterations in cardiac deformation, timing of contraction and relaxation, and early myocardial fibrosis accompany the apparent recovery of acute stress-induced (Takotsubo) cardiomyopathy: an end to the concept of transience. Journal of the American Society of Echocardiography, 30(8), 745-755.
Scopus91 WoS75 Europe PMC472017 Nguyen, T. H., Liu, S., Ong, G. J., Stafford, I., Frenneaux, M. P., & Horowitz, J. D. (2017). Glycocalyx shedding is markedly increased during the acute phase of Takotsubo cardiomyopathy. International Journal of Cardiology, 243, 296-299.
Scopus34 WoS31 Europe PMC142017 Guimarães, P., Wojdyla, D., Alexander, J., Thomas, L., Alings, M., Flaker, G., . . . Lopes, R. (2017). Anticoagulation therapy and clinical outcomes in patients with recently diagnosed atrial fibrillation: Insights from the ARISTOTLE trial. International Journal of Cardiology, 227, 443-449.
Scopus3 WoS3 Europe PMC12017 Packer, M., McMurray, J. J. V., Krum, H., Kiowski, W., Massie, B. M., Caspi, A., . . . Little, T. (2017). Long-Term Effect of Endothelin Receptor Antagonism With Bosentan on the Morbidity and Mortality of Patients With Severe Chronic Heart Failure: Primary Results of the ENABLE Trials. JACC: Heart Failure, 5(5), 317-326.
Scopus98 WoS77 Europe PMC542016 Dawson, D. K., Neil, C. J., Henning, A., Cameron, D., Jagpal, B., Bruce, M., . . . Frenneaux, M. P. (2016). The Authors Reply. JACC: Cardiovascular Imaging, 9(5), 635-636.
2016 Dawson, D. K., Neil, C. J., Henning, A., Cameron, D., Jagpal, B., Bruce, M., . . . Frenneaux, M. P. (2016). The Authors Reply. JACC: Cardiovascular Imaging, 9(5), 633.
2016 Velazquez, E. J., Lee, K. L., Jones, R. H., Al-Khalidi, H. R., Hill, J. A., Panza, J. A., . . . Rouleau, J. L. (2016). Coronary-Artery Bypass Surgery in Patients with Ischemic Cardiomyopathy. NEW ENGLAND JOURNAL OF MEDICINE, 374(16), 1511-1520.
WoS587 Europe PMC3342016 Chong, C., Ong, G., & Horowitz, J. (2016). Emerging drugs for the treatment of angina pectoris. Expert Opinion on Emerging Drugs, 21(4), 365-376.
Scopus10 WoS9 Europe PMC52016 Chen, D., Procter, N., Goh, V., Liu, S., Chua, S., Assadi-Khansari, B., . . . Ngo, D. (2016). New onset atrial fibrillation is associated with elevated galectin-3 levels. International Journal of Cardiology, 223, 48-49.
Scopus18 WoS13 Europe PMC132016 Sverdlov, A. L., Figtree, G. A., Horowitz, J. D., & Ngo, D. T. M. (2016). Interplay between oxidative stress and inflammation in cardiometabolic syndrome. Mediators of Inflammation, 2016, 8254590-1-8254590-3.
Scopus12 WoS11 Europe PMC92016 Tee, S., & Horowitz, J. (2016). Angina pectoris: Why differentiating the type is so important. Medicine Today, 7(6), 27-34. 2016 Procter, N. E. K., & Horowitz, J. D. (2016). Authors' reply. Journal of Geriatric Cardiology, 13(5), 471-472.
2016 Schwarz, K., Singh, S., Parasuraman, S. K., Bruce, M., Shepstone, L., Feelisch, M., . . . Frenneaux, M. P. (2016). A randomized double-blind placebo-controlled crossover trial of sodium nitrate in patients with stable angina INAS. Future Cardiology, 12(6), 617-626.
Scopus4 WoS4 Europe PMC42016 Iyngkaran, P., Toukhsati, S., Thomas, M., Jelinek, M., Hare, D., & Horowitz, J. (2016). A review of the external validity of clinical trials with beta-blockers in heart failure. Clinical Medicine Insights: Cardiology, 10, 163-171.
Scopus2 WoS2 Europe PMC32016 Kemp-Harper, B., Horowitz, J., & Ritchie, R. (2016). Therapeutic potential of nitroxyl (HNO) donors in the management of acute decompensated heart failure. Drugs, 76(14), 1337-1348.
Scopus33 WoS33 Europe PMC202016 Scally, C., Ahearn, T., Rudd, A., Neil, C. J., Srivanasan, J., Jagpal, B., . . . Dawson, D. K. (2016). Right ventricular involvement and recovery after acute stress-induced (Tako-tsubo) cardiomyopathy. American Journal of Cardiology, 117(5), 775-780.
Scopus25 WoS20 Europe PMC132016 Iyngkaran, P., Kangaharan, N., Zimmet, H., Arstall, M., Minson, R., Thomas, M., . . . Ilton, M. (2016). Heart failure in minority populations - Impediments to optimal treatment in Australian aborigines. Current Cardiology Reviews, 12(3), 166-179.
Scopus5 WoS3 Europe PMC22016 Procter, N. E., & Horowitz, J. D. (2016). Platelet reactivity in patients with atrial fibrillation Reply. JOURNAL OF GERIATRIC CARDIOLOGY, 13(5), 471-472. 2016 Phuong, H., Choi, B., Chong, C., Raman, B., & Horowitz, J. (2016). Can perhexiline be utilized without long-term toxicity? A clinical practice audit. Therapeutic Drug Monitoring, 38(1), 73-78.
Scopus13 WoS11 Europe PMC62016 Procter, N., Ball, J., Ngo, D., Chirkov, Y., Isenberg, J., Hylek, E., . . . Horowitz, J. (2016). Platelet hyperaggregability in patients with atrial fibrillation: Evidence of a background proinflammatory milieu. Herz, 41(1), 57-62.
Scopus9 WoS11 Europe PMC42016 Tully, P. J., Turnbull, D. A., Horowitz, J. D., Beltrame, J. F., Selkow, T., Baune, B. T., . . . Wittert, G. A. (2016). Cardiovascular Health in Anxiety or Mood Problems Study (CHAMPS): study protocol for a randomized controlled trial. Trials, 17(1), 18-1-18-10.
Scopus13 WoS10 Europe PMC82016 Hijazi, Z., Aulin, J., Andersson, U., Alexander, J., Gersh, B., Granger, C., . . . Wallentin, L. (2016). Biomarkers of inflammation and risk of cardiovascular events in anticoagulated patients with atrial fibrillation. Heart, 102(7), 508-517.
Scopus69 WoS63 Europe PMC372016 De Caterina, R., Andersson, U., Alexander, J., Al-Khatib, S., Bahit, M., Goto, S., . . . Wallentin, L. (2016). History of bleeding and outcomes with apixaban versus warfarin in patients with atrial fibrillation in the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation trial. American Heart Journal, 175, 175-183.
Scopus17 WoS14 Europe PMC72016 Procter, N., Goh, V., Mahadevan, G., Stewart, S., & Horowitz, J. (2016). Platelet reactivity is independent of left atrial wall deformation in patients with atrial fibrillation. Mediators of Inflammation, 2016, 9754808-1-9754808-5.
Scopus3 WoS3 Europe PMC32016 Chong, C., Sallustio, B., & Horowitz, J. (2016). Drugs that Affect Cardiac Metabolism: focus on Perhexiline. Cardiovascular Drugs and Therapy, 30(4), 399-405.
Scopus22 WoS19 Europe PMC132016 Procter, N., Ball, J., Ngo, D., Isenberg, J., Hylek, E., Chirkov, Y., . . . Horowitz, J. (2016). Gender and tachycardia: independent modulation of platelet reactivity in patients with atrial fibrillation. Journal of Geriatric Cardiology, 13(3), 202-208.
WoS5 Europe PMC42016 Procter, N., Stewart, S., & Horowitz, J. (2016). New-onset atrial fibrillation and thromboembolic risk: Cardiovascular syzygy?. Heart Rhythm, 13(6), 1355-1361.
Scopus15 WoS13 Europe PMC62016 Procter, N. E. K., Hurst, N. L., Nooney, V. B., Imam, H., De Caterina, R., Chirkov, Y. Y., & Horowitz, J. D. (2016). New Developments in Platelet Cyclic Nucleotide Signalling: Therapeutic Implications. Cardiovascular Drugs and Therapy, 30(5), 505-513.
Scopus8 WoS8 Europe PMC52016 Chua, S. J., Ajaero, C., Assadi-Khansari, B., Mcgavigan, A., Horowitz, J. D., Ngo, D. T., & Sverdlov, A. L. (2016). Galectin 3 predicts improvement in LV volumes after Cardiac Resynchronisation Therapy. EUROPEAN JOURNAL OF HEART FAILURE, 18, 232. 2016 Amarasekera, A., Sverdlov, A., Horowitz, J., & Ngo, D. (2016). Elevated parathyroid hormone predicts high asymmetric dimethylarginine (ADMA) concentrations in obese diabetic patients. Diabetes and Metabolism, 42(5), 378-381.
Scopus3 WoS3 Europe PMC22015 Horowitz, J., Chong, C., Ngo, D., & Sverdlov, A. (2015). Effects of acute hyperglycaemia on cardiovascular homeostasis: Does a spoonful of sugar make the flow-mediated dilatation go down?. Journal of Thoracic Disease, 7(12), 607-611.
Scopus4 WoS3 Europe PMC42015 Chong, C., Drury, N., Licari, G., Frenneaux, M., Horowitz, J., Pagano, D., & Sallustio, B. (2015). Stereoselective handling of perhexiline: implications regarding accumulation within the human myocardium. European Journal of Clinical Pharmacology, 71(12), 1485-1491.
Scopus11 WoS9 Europe PMC62015 Procter, N., Ball, J., Liu, S., Hurst, N., Nooney, V., Goh, V., . . . Horowitz, J. (2015). Impaired platelet nitric oxide response in patients with new onset atrial fibrillation. International Journal of Cardiology, 179, 160-165.
Scopus21 WoS22 Europe PMC142015 Chong, C., Liu, S., Licari, G., Heresztyn, T., Chirkov, Y., Ngo, D., & Horowitz, J. (2015). Reversal of hyperglycemia: effects on nitric oxide signaling. American Journal of Medicine, 128(4), 427-430.
Scopus6 WoS6 Europe PMC52015 Singh, K., Chong, C. R., Nguyen, T. H., Stansborough, J., & Horowitz, J. D. (2015). Reply: Takotsubo syndrome is a systemic, rather than merely a cardiac, disease: Possible effects on the systemic and pulmonary vasculature. Heart Lung and Circulation, 24(4), 417-418.
2015 Procter, N. E., Ball, J., Heresztyn, T., Nooney, V. B., Liu, S., Chong, C. -R., . . . Horowitz, J. D. (2015). Subtle renal dysfunction and bleeding risk in atrial fibrillation: symmetric dimethylarginine predicts HAS-BLED score.. American journal of cardiovascular disease, 5(2), 101-109.
WoS12015 Hijazi, Z., Siegbahn, A., Andersson, U., Lindahl, B., Granger, C., Alexander, J., . . . Wallentin, L. (2015). Comparison of cardiac troponins I and T measured with high-sensitivity methods for evaluation of prognosis in atrial fibrillation: an ARISTOTLE substudy. Clinical Chemistry, 61(2), 368-378.
Scopus44 WoS40 Europe PMC212015 Liu, S., Ngo, D., Chong, C., Amarasekera, A., Procter, N., Licari, G., . . . Horowitz, J. (2015). Suppression of neutrophil superoxide generation by BNP is attenuated in acute heart failure: a case for 'BNP resistance'. European Journal of Heart Failure, 17(5), 475-483.
Scopus11 WoS9 Europe PMC82015 Neil, C., Nguyen, T., Singh, K., Raman, B., Stansborough, J., Dawson, D., . . . Horowitz, J. (2015). Relation of delayed recovery of myocardial function after takotsubo cardiomyopathy to subsequent quality of life. American Journal of Cardiology, 115(8), 1085-1089.
Scopus42 WoS34 Europe PMC182015 Nooney, V., Hurst, N., Chirkov, Y., De Caterina, R., & Horowitz, J. (2015). Post receptor determinants of acute platelet response to clopidogrel in patients with symptomatic myocardial ischemia. Vascular Pharmacology, 65-66, 17-22.
Scopus5 WoS5 Europe PMC12015 Surikow, S., Raman, B., Licari, J., Singh, K., Nguyen, T., & Horowitz, J. (2015). Evidence of nitrosative stress within hearts of patients dying of Tako-tsubo cardiomyopathy. International Journal of Cardiology, 189(1), 112-114.
Scopus23 WoS23 Europe PMC142015 Tully, P., Wittert, G., Turnbull, D., Beltrame, J., Horowitz, J., Cosh, S., & Baumeister, H. (2015). Panic disorder and incident coronary heart disease: a systematic review and meta-analysis protocol. Systematic Reviews, 4(1), 33-1-33-8.
Scopus8 WoS6 Europe PMC12015 Stewart, S., Ball, J., Horowitz, J., Marwick, T., Mahadevan, G., Wong, C., . . . Carrington, M. (2015). Standard versus atrial fibrillation-specific management strategy (SAFETY) to reduce recurrent admission and prolong survival: pragmatic, multicentre, randomised controlled trial. The Lancet, 385(9970), 775-784.
Scopus104 WoS98 Europe PMC572015 Arif, S., Borgognone, A., Lin, E., O'Sullivan, A., Sharma, V., Drury, N., . . . Madhani, M. (2015). Role of aldehyde dehydrogenase in hypoxic vasodilator effects of nitrite in rats and humans. British Journal of Pharmacology, 172(13), 3341-3352.
Scopus11 WoS9 Europe PMC102015 Ahearn, T., Jagpal, B., Cameron, D., Ng, B. K., Scally, C., Higgins, D. M., . . . Dawson, D. K. (2015). Dynamic changes of the extracellular matrix after acute tako-tsubo cardiomyopathy. Journal of Cardiovascular Magnetic Resonance, 17(Suppl 1), 1.
2015 Tully, P., Turnbull, D., Beltrame, J., Horowitz, J., Cosh, S., Baumeister, H., & Wittert, G. (2015). Panic disorder and incident coronary heart disease: a systematic review and meta-regression in 1 131 612 persons and 58 111 cardiac events. Psychological Medicine, 45(14), 2909-2920.
Scopus59 WoS42 Europe PMC242015 Hurst, N. L., Nooney, V. B., Chirkov, Y. Y., De Caterina, R., & Horowitz, J. D. (2015). Determinants of subacute response to clopidogrel: Relative impact of CYP2C19 genotype and PGE(1)/adenylate cyclase signalling. Thrombosis Research, 136(2), 308-314.
Scopus8 WoS8 Europe PMC32015 Bonaca, M. P., Bhatt, D. L., Cohen, M., Steg, P. G., Storey, R. F., Jensen, E. C., . . . Stepanov, N. (2015). Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. NEW ENGLAND JOURNAL OF MEDICINE, 372(19), 1791-1800.
WoS1389 Europe PMC7802015 Beadle, R., Williams, L., Kuehl, M., Bowater, S., Abozguia, K., Leyva, F., . . . Frenneaux, M. (2015). Improvement in cardiac energetics by perhexiline in heart failure due to dilated cardiomyopathy. JACC: Heart Failure, 3(3), 202-211.
Scopus74 Europe PMC522015 Chang, S., Davidson, P., Newton, P., Macdonald, P., Carrington, M., Marwick, T., . . . On behalf of the WHICH Investigators. (2015). Composite outcome measures in a pragmatic clinical trial of chronic heart failure management: a comparative assessment. International Journal of Cardiology, 185, 62-68.
Scopus9 WoS9 Europe PMC52015 Ball, J., Carrington, M., Thompson, D., Horowitz, J., & Stewart, S. (2015). Post-discharge electrocardiogram Holter monitoring in recently hospitalised individuals with chronic atrial fibrillation to enhance therapeutic monitoring and identify potentially predictive phenotypes. European Journal of Cardiovascular Nursing, 14(5), 384-394.
Scopus4 WoS3 Europe PMC22015 Scally, C., Neil, C. J., Srinivasan, J., Jagpal, B., Ng, B. K., Frenneaux, M. P., . . . Dawson, D. K. (2015). Right ventricular involvement in Tako-tsubo cardiomyopathy - insights from cardiovascular magnetic resonance. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 17(Suppl 1), P280.
2015 Dawson, D. K., Neil, C. J., Henning, A., Cameron, D., Jagpal, B., Bruce, M., . . . Frenneaux, M. P. (2015). Tako-Tsubo cardiomyopathy: A heart stressed out of energy?. JACC: Cardiovascular Imaging, 8(8), 983-989.
Scopus57 WoS53 Europe PMC352015 Cannon, C. P., Blazing, M. A., Giugliano, R. P., McCagg, A., White, J. A., Theroux, P., . . . Bono, J. (2015). Ezetimibe added to statin therapy after acute coronary syndromes. New England Journal of Medicine, 372(25), 2387-2397.
Scopus3244 Europe PMC16352014 Singh, S., Schwarz, K., Horowitz, J., & Frenneaux, M. (2014). Cardiac energetic impairment in heart disease and the potential role of metabolic modulators a review for clinicians. Circulation: Cardiovascular Genetics, 7(5), 720-728.
Scopus18 WoS13 Europe PMC102014 Siddiqi, N., Neil, C., Bruce, M., MacLennan, G., Cotton, S., Papadopoulou, S., . . . Frenneaux, M. (2014). Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI). European Heart Journal, 35(19), 1255-+.
Scopus118 WoS105 Europe PMC802014 Bailey, J., Feelisch, M., Horowitz, J., Frenneaux, M., & Madhani, M. (2014). Pharmacology and therapeutic role of inorganic nitrite and nitrate in vasodilatation. Pharmacology and Therapeutics, 144(3), 303-320.
Scopus43 WoS40 Europe PMC252014 Singh, K., Neil, C., Nguyen, T., Stansborough, J., Chong, C., Dawson, D., . . . Horowitz, J. (2014). Dissociation of early shock in Takotsubo cardiomyopathy from either right or left ventricular systolic dysfunction. Heart, Lung and Circulation, 23(12), 1141-1148.
Scopus23 WoS22 Europe PMC142014 Goto, S., Zhu, J., Liu, L., Oh, B., Wojdyla, D., Aylward, P., . . . Alexander, J. (2014). Efficacy and safety of apixaban compared with warfarin for stroke prevention in patients with atrial fibrillation from East Asia: A subanalysis of the apixaban for reduction in stroke and other thromboembolic events in atrial fibrillation (ARISTOTLE) trial. American Heart Journal, 168(3), 303-309.
Scopus124 WoS112 Europe PMC752014 Christersson, C., Wallentin, L., Andersson, U., Alexander, J., Ansell, J., De Caterina, R., . . . Siegbahn, A. (2014). D-dimer and risk of thromboembolic and bleeding events in patients with atrial fibrillation - observations from the ARISTOTLE trial. Journal of Thrombosis and Haemostasis, 12(9), 1401-1412.
Scopus78 WoS73 Europe PMC462014 Raman, B., Singh, K., Zeitz, C. J., & Horowitz, J. D. (2014). Takotsubo cardiomyopathy presenting as S-T elevation myocardial infarction: Not gone but forgotten?. International Journal of Cardiology, 172(1), E261-E262.
Scopus11 WoS11 Europe PMC62014 Wallentin, L., Lopes, R. D., Hanna, M., Thomas, L., Hellkamp, A., Nepal, S., . . . Granger, C. B. (2014). Response to letter regarding article, "efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for stroke prevention in atrial fibrillation". Circulation, 129(2), e21-e22.
Scopus1 WoS12014 Procter, N., Chong, C., Sverdlov, A., Chan, W., Chirkov, Y., & Horowitz, J. (2014). Aging of platelet nitric oxide signaling: pathogenesis, clinical implications, and therapeutics. Seminars in Thrombosis and Hemostasis, 40(6), 660-668.
Scopus13 WoS11 Europe PMC82014 Sverdlov, A., Ngo, D., Chan, W., Chirkov, Y., & Horowitz, J. (2014). Aging of the nitric oxide system: are we as old as our NO?. Journal of the American Heart Association, 3(4), e000973-1-e000973-12.
Scopus64 WoS53 Europe PMC402014 Liu, S., Ngo, D., Stewart, S., Horowitz, J., & Chirkov, Y. (2014). B-Type natriuretic peptide suppression of neutrophil superoxide generation: mechanistic studies in normal subjects. Clinical and Experimental Pharmacology and Physiology, 41(10), 739-743.
Scopus7 WoS7 Europe PMC62014 Chong, C., Chan, W., Nguyen, T., Liu, S., Procter, N., Ngo, D., . . . Horowitz, J. (2014). Thioredoxin-interacting protein: pathophysiology and emerging pharmacotherapeutics in cardiovascular disease and diabetes. Cardiovascular Drugs and Therapy, 28(4), 347-360.
Scopus70 WoS67 Europe PMC512014 Dautov, R., Stafford, I., Liu, S., Cullen, H., Chirkov, Y., & Horowitz, J. (2014). Hypoxic potentiation of nitrite effects in human vessels and platelets. Nitric Oxide: Biology and Chemistry, 40, 36-44.
Scopus20 WoS18 Europe PMC132014 Stewart, S., Carrington, M., Horowitz, J., Marwick, T., Newton, P., Davidson, P., . . . Scuffham, P. (2014). Prolonged impact of home versus clinic-based management of chronic heart failure: extended follow-up of a pragmatic, multicentre randomized trial cohort. International Journal of Cardiology, 174(3), 600-610.
Scopus29 WoS26 Europe PMC192014 Ali, O., Chapman, M., Thanh, H., Chirkov, Y., Heresztyn, T., Mundisugih, J., & Horowitz, J. (2014). Interactions between inflammatory activation and endothelial dysfunction selectively modulate valve disease progression in patients with bicuspid aortic valve. Heart, 100(10), 800-805.
Scopus37 WoS34 Europe PMC282014 Kayacelebi, A., Nguyen, T., Neil, C., Horowitz, J., Jordan, J., & Tsikas, D. (2014). Homoarginine and 3-nitrotyrosine in patients with takotsubo cardiomyopathy. International Journal of Cardiology, 173(3), 546-547.
Scopus28 WoS26 Europe PMC192014 Horowitz, J. D., & Nguyen, T. H. (2014). Role of echocardiography in tako-tsubo cardiomyopathy: Beyond diagnosis?. JACC: Cardiovascular Imaging, 7(2), 130-132.
Scopus1 WoS1 Europe PMC12014 Mahadavan, G., Nguyen, T., & Horowitz, J. (2014). Brain natriuretic peptide: a biomarker for all cardiac disease?. Current Opinion in Cardiology, 29(2), 160-166.
Scopus30 WoS26 Europe PMC192014 Sheikh, A. R., Westley, I., Sallustio, B., Horowitz, J. D., & Beltrame, J. F. (2014). Interaction of terbinafine (anti-fungal agent) with perhexiline: a case report. Heart, Lung and Circulation, 23(6), e149-e151.
Scopus8 WoS6 Europe PMC42014 Drury, N., Licari, G., Chong, C., Howell, N., Frenneaux, M., Horowitz, J., . . . Sallustio, B. (2014). Relationship between plasma, atrial and ventricular perhexiline concentrations in humans: insights into factors affecting myocardial uptake. British Journal of Clinical Pharmacology, 77(5), 789-795.
Scopus9 WoS9 Europe PMC82014 Hijazi, Z., Wallentin, L., Siegbahn, A., Andersson, U., Alexander, J., Atar, D., . . . Granger, C. (2014). High-sensitivity troponin T and risk stratification in patients with atrial fibrillation during treatment with apixaban or warfarin. Journal of the American College of Cardiology, 63(1), 52-61.
Scopus129 WoS122 Europe PMC772014 Wallentin, L., Hijazi, Z., Andersson, U., Alexander, J., De Caterina, R., Hanna, M., . . . Siegbahn, A. (2014). Growth differentiation factor 15, a marker of oxidative stress and inflammation, for risk assessment in patients with atrial fibrillation: insights from the Apixaban for reduction in stroke and other thromboembolic events in atrial fibrillation (ARISTOTLE) trial. Circulation, 130(21), 1847-1858.
Scopus235 WoS220 Europe PMC1372014 Nicholls, S. J., Kastelein, J. J. P., Schwartz, G. G., Bash, D., Rosenson, R. S., Cavender, M. A., . . . Nissen, S. E. (2014). Varespladib and cardiovascular events in patients with an acute coronary syndrome: the VISTA-16 randomized clinical trial. JAMA - Journal of the American Medical Association, 311(3), 252-262.
Scopus256 WoS214 Europe PMC1702014 Nicholls, S. J., Kastelein, J. J. P., Schwartz, G. G., Bash, D., Rosenson, R. S., Cavender, M. A., . . . Nissen, S. E. (2014). Varespladib and cardiovascular events in patients with an acute coronary syndrome: the VISTA-16 randomized clinical trial. JAMA - Journal of the American Medical Association, 311(3), 252-262.
Scopus256 WoS214 Europe PMC1702014 Hijazi, Z., Siegbahn, A., Andersson, U., Granger, C., Alexander, J., Atar, D., . . . Wallentin, L. (2014). High-sensitivity troponin I for risk assessment in patients with atrial fibrillation: Insights from the apixaban for reduction in stroke and other thromboembolic events in atrial fibrillation (ARISTOTLE) trial. Circulation, 129(6), 625-634.
Scopus106 WoS99 Europe PMC662014 Singh, K., Carson, K., Usmani, Z., Sawhney, G., Shah, R., & Horowitz, J. (2014). Systematic review and meta-analysis of incidence and correlates of recurrence of takotsubo cardiomyopathy. International Journal of Cardiology, 174(3), 696-701.
Scopus190 WoS177 Europe PMC1202014 Singh, K., Carson, K., Shah, R., Sawhney, G., Singh, B., Parsaik, A., . . . Horowitz, J. (2014). Meta-analysis of clinical correlates of acute mortality in takotsubo cardiomyopathy. American Journal of Cardiology, 113(8), 1420-1428.
Scopus158 WoS136 Europe PMC912013 Chong, C. R., Neil, C. J., Nguyen, T. H., Singh, K., & Horowitz, J. D. (2013). Reply. Clinical Cardiology, 36(10), E33.
2013 Chong, C. R., & Horowitz, J. D. (2013). Letters to the editor. Clinical Cardiology, 36(8), 492-493.
2013 Beltrame, J. F., & Horowitz, J. D. (2013). Why do nitrates have limited efficacy in coronary microvessels?. Cardiovascular Drugs and Therapy, 27(3), 187-188.
Scopus6 WoS3 Europe PMC22013 Carrington, M., Ball, J., Horowitz, J., Marwick, T., Mahadevan, G., Wong, C., . . . Stewart, S. (2013). Navigating the fine line between benefit and risk in chronic atrial fibrillation: rationale and design of the Standard versus Atrial Fibrillation spEcific managemenT studY (SAFETY). International Journal of Cardiology, 166(2), 359-365.
Scopus13 WoS16 Europe PMC142013 Singh, K., Marinelli, T., & Horowitz, J. (2013). Takotsubo cardiomyopathy after anti-influenza vaccination: catecholaminergic effects of immune system. American Journal of Emergency Medicine, 31(11), 1627.e1-1627.e4.
Scopus20 WoS18 Europe PMC202013 Das, D., Holmes, A., Mishra, K., Rosenkranz, A., Horowitz, J., & Kennedy, J. (2013). TGF-β1-induced MAPK activation promotes collagen synthesis, nodule formation, redox stress and cellular senescence in porcine aortic valve interstitial cells. Journal of Heart Valve Disease, 22(5), 621-630.
Scopus30 WoS27 Europe PMC232013 Ngo, D., Horowitz, J., & Sverdlov, A. (2013). Heart failure: a corin-deficient state?. Hypertension, 61(2), 284-285.
Scopus15 WoS14 Europe PMC112013 Nguyen, T., Neil, C., Sverdlov, A., Ngo, D., Chan, W., Heresztyn, T., . . . Horowitz, J. (2013). Enhanced NO signaling in patients with Takotsubo cardiomyopathy: short-term pain, long-term gain?. Cardiovascular Drugs and Therapy, 27(6), 541-547.
Scopus36 WoS30 Europe PMC142013 Sorich, M., Horowitz, J., Sorich, W., Wiese, M., Pekarsky, B., & Karnon, J. (2013). Cost-effectiveness of using CYP2C19 genotype to guide selection of clopidogrel or ticagrelor in Australia. Pharmagenomics, 14(16), 2013-2021.
Scopus31 WoS25 Europe PMC192013 Hurst, N., Nooney, V., Raman, B., Chirkov, Y., De Caterina, R., & Horowitz, J. (2013). Clopidogrel "resistance": Pre- vs post-receptor determinants. Vascular Pharmacology, 59(5-6), 152-161.
Scopus19 WoS17 Europe PMC92013 Sverdlov, A., Chan, W., Procter, N., Chirkov, Y., Ngo, D., & Horowitz, J. (2013). Reciprocal regulation of NO signaling and TXNIP expression in humans: Impact of aging and ramipril therapy. International Journal of Cardiology, 168(5), 4624-4630.
Scopus31 WoS34 Europe PMC262013 Dautov, R., Ngo, D., Licari, G., Liu, S., Sverdlov, A., Ritchie, R., . . . Chirkov, Y. (2013). The nitric oxide redox sibling nitroxyl partially circumvents impairment of platelet nitric oxide responsiveness. Nitric Oxide-Biology and Chemistry, 35, 72-78.
Scopus22 WoS21 Europe PMC112013 Chan, W., Ngo, D., Sverdlov, A., Rajendran, S., Stafford, I., Heresztyn, T., . . . Horowitz, J. (2013). Premature aging of cardiovascular/platelet function in polycystic ovarian syndrome. American Journal of Medicine, 126(7), 1-7.
Scopus13 WoS5 Europe PMC42013 Chong, C., Neil, C., Nguyen, T., Stansborough, J., Law, G., Singh, K., & Horowitz, J. (2013). Dissociation between severity of takotsubo cardiomyopathy and presentation with shock or hypotension. Clinical Cardiology, 36(7), 401-406.
Scopus43 WoS39 Europe PMC312013 Horowitz, J. (2013). Efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for Stroke prevention in atrial fibrillation. Circulation, 127(22), 2166-2176.
Scopus193 WoS168 Europe PMC1272013 Hijazi, Z., Wallentin, L., Siegbahn, A., Andersson, U., Christersson, C., Ezekowitz, J., . . . Granger, C. (2013). N-terminal pro-B-type natriuretic peptide for risk assessment in patients with atrial fibrillation: Insights from the aristotle trial (apixaban for the prevention of stroke in subjects with atrial fibrillation). Journal of the American College of Cardiology, 61(22), 2274-2284.
Scopus184 WoS170 Europe PMC1142013 Maher, A., Arif, S., Madhani, M., Abozguia, K., Ahmed, I., Fernandez, B., . . . Frennaux, M. (2013). Impact of chronic congestive heart failure on pharmacokinetics and vasomotor effects of infused nitrite. British Journal of Pharmacology, 169(3), 659-670.
Scopus20 WoS19 Europe PMC162013 Whitty, J., Stewart, S., Carrington, M., Calderone, A., Marwick, T., Horowitz, J., . . . Scuffham, P. (2013). Patient preferences and willingness-to-pay for a home or clinic based program of chronic heart failure management: findings from the which? trial. PLoS One, 8(3), 1-8.
Scopus30 WoS28 Europe PMC222013 Irvine, J., Cao, N., Gossain, S., Alexander, A., Love, J., Qin, C., . . . Ritchie, R. (2013). HNO/cGMP-dependent antihypertrophic actions of isopropylamine-NONOate in neonatal rat cardiomyocytes: Potential therapeutic advantages of HNO over NȮ. American Journal of Physiology - Heart and Circulatory Physiology, 305(3), 365-377.
Scopus26 WoS27 Europe PMC202013 Figtree, G., Bagnall, R., Abdulla, I., Buchholz, S., Galougahi, K., Yan, W., . . . Ward, M. (2013). No association of G-protein-coupled receptor kinase 5 or β-adrenergic receptor polymorphisms with Takotsubo cardiomyopathy in a large Australian cohort. European Journal of Heart Failure, 15(7), 730-733.
Scopus45 WoS43 Europe PMC322013 Siddiqi, N., Bruce, M., Neil, C. J., Jagpal, B., Maclennon, G., Cotton, S. C., . . . Frenneaux, M. P. (2013). Protocol: Does sodium nitrite administration reduce ischaemia-reperfusion injury in patients presenting with acute ST segment elevation myocardial infarction? Nitrites in acute myocardial infarction (NIAMI). Journal of Translational Medicine, 11(1), 8 pages.
Scopus14 WoS14 Europe PMC112013 Kitoh, H., Achiwa, M., Kaneko, H., Mishima, K., Matsushita, M., Kadono, I., . . . Ishiguro, N. (2013). Perhexiline maleate in the treatment of fibrodysplasia ossificans progressiva: an open-labeled clinical trial. Orphanet Journal of Rare Diseases, 8(1), 163-1-163-7.
Scopus13 WoS14 Europe PMC122013 Ritchie, R., Irvine, J., Cao, N., Gossain, S., Alexander, A., Love, J., . . . Kemp-Harper, B. K. (2013). The nitroxyl donor isopropylamine-NONOate elicits soluble guanylyl cyclase-dependent antihypertrophic actions: comparison of the potential therapeutic advantages of HNO over NO•. BMC pharmacology & toxicology, 14(Suppl 1), P56.
2012 Iachini Bellisarii, F., Radico, F., Muscente, F., Horowitz, J., & De Caterina, R. (2012). Nitrates and other nitric oxide donors in cardiology - Current positioning and perspectives. Cardiovascular Drugs and Therapy, 26(1), 55-69.
Scopus15 WoS13 Europe PMC72012 Irvine, J., Ganthavee, V., Love, J., Alexander, A., Horowitz, J., Stasch, J., . . . Ritchie, R. (2012). The soluble guanylyl cyclase activator bay 58-2667 selectively limits cardiomyocyte hypertrophy. PLoS ONE, 7(11), 1-11.
Scopus48 WoS42 Europe PMC272012 Lopes, R., Al-Khatib, S., Wallentin, L., Yang, H., Ansell, J., Bahit, M., . . . Alexander, J. (2012). Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fibrillation: a secondary analysis of a randomised controlled trial. Lancet, 380(9855), 1749-1758.
Scopus172 WoS152 Europe PMC1052012 Sverdlov, A., Ngo, D., Chan, W., Chirkov, Y., Gersh, B., McNeil, J., & Horowitz, J. (2012). Determinants of aortic sclerosis progression: implications regarding impairment of nitric oxide signalling and potential therapeutics. European Heart Journal, 33(19), 2419-2425.
Scopus26 WoS24 Europe PMC212012 Gilutz, H., & Horowitz, J. (2012). Erythropoietin studies should not be abandoned. American Heart Journal, 164(3), 5.
2012 Stewart, S., Carrington, M., Marwick, T., Davidson, P., Macdonald, P., Horowitz, J., . . . Scuffham, P. (2012). Impact of home versus clinic-based management of chronic heart failure: the WHICH? (Which heart failure intervention is most cost-effective & consumer friendly in reducing hospital care) multicenter, randomized trial. Journal of the American College of Cardiology, 60(14), 1239-1248.
Scopus112 WoS99 Europe PMC812012 Willoughby, S., Rajendran, S., Chan, W., Procter, N., Leslie, S., Liberts, E., . . . Horowitz, J. (2012). Ramipril sensitizes platelets to nitric oxide: Implications for therapy in high-risk patients. Journal of the American College of Cardiology, 60(10), 887-894.
Scopus44 WoS43 Europe PMC322012 Neil, C., Nguyen, T., Kucia, A., Crouch, B., Sverdlov, A., Chirkov, Y., . . . Horowitz, J. (2012). Slowly resolving global myocardial inflammation/oedema in Tako-Tsubo cardiomyopathy: evidence from T2-weighted cardiac MRI. Heart, 98(17), 1278-1284.
Scopus94 WoS85 Europe PMC592012 Ngo, D., Sverdlov, A., & Horowitz, J. (2012). Prevention of aortic valve stenosis: a realistic therapeutic target?. Pharmacology & Therapeutics, 135(1), 78-93.
Scopus20 WoS18 Europe PMC152012 Rogers, N., Stephenson, M., Kitching, A., Horowitz, J., & Coates, P. (2012). Amelioration of renal ischaemia-reperfusion injury by liposomal delivery of curcumin to renal tubular epithelial and antigen-presenting cells. British Journal of Pharmacology, 166(1), 194-209.
Scopus44 WoS43 Europe PMC312012 Rosenson, R., Horowitz, J., Kaski, J., Krum, H., & Remme, W. (2012). Clinical Trials Update Esc Congress 2011. Cardiovascular Drugs and Therapy, 26(1), 77-84.
Scopus2 WoS1 Europe PMC12012 Gilutz, H., Frenneaux, M., & Horowitz, J. (2012). A case series of concomitant treatment of perhexiline with Amiodarone. Therapeutic Drug Monitoring, 34(2), 227-231.
Scopus1 WoS12012 Neil, C., Nguyen, T., Sverdlov, A., Chirkov, Y., Chong, C., Stansborough, J., . . . Horowitz, J. (2012). Can we make sense of takotsubo cardiomyopathy? An update on pathogenesis, diagnosis and natural history. Expert Review of Cardiovascular Therapy, 10(2), 215-221.
Scopus20 WoS14 Europe PMC132012 Chan, W., & Horowitz, J. (2012). Thrombospondin-1 in pulmonary arterial hypertension: what ails NOS?. Cardiovascular Research, 93(4), 540-542.
2012 Neil, C., Chong, C., Nguyen, T., & Horowitz, J. (2012). Occurrence of Tako-Tsubo cardiomyopathy in association with ingestion of serotonin/noradrenaline reuptake inhibitors. Heart, Lung & Circulation (Print Edition), 21(4), 203-205.
Scopus41 WoS35 Europe PMC232012 Sverdlov, A., Ngo, D., & Horowitz, J. (2012). Pathogenesis of aortic sclerosis: association with low BMI, tissue nitric oxide resistance, but not systemic inflammatory activation. American Journal of Cardiovascular Disease, 2(1), 43-49.
WoS6 Europe PMC62012 Nguyen, T., Horowitz, J., & Unger, S. (2012). Tachycardic vs. pharmacologic stress myocardial perfusion imaging: differential implications in multi-vessel ischemia. American Journal of Cardiovascular Disease, 2(1), 34-42.
Europe PMC12012 Sverdlov, A., Ngo, D., & Horowitz, J. (2012). Redefining the natural history of calcific aortic stenosis: lessons from Laennec. Journal of Internal Medicine, 271(6), 569-572.
Scopus1 WoS1 Europe PMC12011 Horowitz, J., Rosenson, R., McMurray, J., Marx, N., & Remme, W. (2011). Clinical Trials Update AHA Congress 2010. Cardiovascular Drugs and Therapy, 25(1), 69-76.
Scopus9 WoS8 Europe PMC92011 Ling, L., Chik, W., Averbuj, P., Pati, P., Sverdlov, A., Ngo, D., . . . Horowitz, J. (2011). Effects of aging, renal dysfunction, left ventricular systolic impairment, and weight on steady state pharmacokinetics of perhexiline. Therapeutic Drug Monitoring, 33(2), 251-256.
Scopus4 WoS4 Europe PMC32011 Ngo, D., Stafford, I., Sverdlov, A., Qi, W., Wuttke, R., Zhang, Y., . . . Horowitz, J. (2011). Ramipril retards development of aortic valve stenosis in a rabbit model: mechanistic considerations. British Journal of Pharmacology, 162(3), 722-732.
Scopus31 WoS30 Europe PMC252011 Nightingale, A., Sverdlov, A., Rajendran, S., Mishra, K., Heresztyn, T., Ngo, D., & Horowitz, J. (2011). Lack of association between aortic sclerosis and left ventricular hypertrophy in elderly subjects. International Journal of Cardiology, 150(1), 33-38.
Scopus9 WoS7 Europe PMC52011 Lopes, R., Horowitz, J., Garcia, D., Crowther, M., & Hylek, E. (2011). Warfarin and acetaminophen interaction: a summary of the evidence and biologic plausibility. Blood, 118(24), 6269-6273.
Scopus29 WoS23 Europe PMC182011 Nordin, B., Lewis, J., Daly, R., Horowitz, J., Metcalfe, A., Lange, K., & Prince, R. (2011). The calcium scare - what would Austin Bradford Hill have thought?. Osteoporosis International, 22(12), 3073-3077.
Scopus40 WoS36 Europe PMC282011 Nguyen, T., Neil, C., Sverdlov, A., Mahadevan, G., Chirkov, Y., Kucia, A., . . . Horowitz, J. (2011). N-terminal pro-brain natriuretic protein levels in takotsubo cardiomyopathy. American Journal of Cardiology, 108(9), 1316-1321.
Scopus113 WoS97 Europe PMC782011 Ngo, D., Chan, W., Rajendran, S., Heresztyn, T., Amarasekera, A., Sverdlov, A., . . . Horowitz, J. (2011). Determinants of insulin responsiveness in young women: Impact of polycystic ovarian syndrome, nitric oxide, and vitamin D. Nitric Oxide-Biology and Chemistry, 25(3), 326-330.
Scopus56 WoS46 Europe PMC342011 Granger, C., Alexander, J., McMurray, J., Lopes, R., Hylek, E., Hanna, M., . . . Wallertin, L. (2011). Apixaban versus Warfarin in patients with atrial fibrillation. New England Journal of Medicine, 365(11), 981-992.
Scopus7301 WoS5851 Europe PMC40342011 Stewart, S., Carrington, M., Marwick, T., Davidson, P., Macdonald, P., Horowitz, J., . . . Scuffham, P. (2011). The WHICH? trial: rationale and design of a pragmatic randomized, multicentre comparison of home- vs. clinic-based management of chronic heart failure patients. European Journal of Heart Failure, 13(8), 909-916.
Scopus36 WoS32 Europe PMC292011 Sverdlov, A., Ngo, D., Nightingale, A., Rajendran, S., Mishra, K., Heresztyn, T., . . . Horowitz, J. (2011). The endogenous NOS inhibitor asymmetric dimethylarginine (ADMA) predicts LV mass independent of afterload. Nitric Oxide-Biology and Chemistry, 25(1), 41-46.
Scopus14 WoS13 Europe PMC112011 Sverdlov, A., Ngo, D., Chapman, M., Ali, O., Chirkov, Y., & Horowitz, J. (2011). Pathogenesis of aortic stenosis: not just a matter of wear and tear. American Journal of Cardiovascular Disease, 1(2), 185-199.
WoS44 Europe PMC282011 Ngo, D. T., Drury, N. E., Pagano, D., Frenneaux, M. P., & Horowitz, J. D. (2011). How Does Perhexiline Modulate Myocardial Energetics and Ameliorate Redox Stress?. CIRCULATION, 124(21), 2 pages.
WoS62011 Chan, W. P. A., Sverdlov, A. L., Ngo, D. T., Rajendran, S., Chirkov, Y. Y., & Horowitz, J. D. (2011). Impact of ageing on the platelet and vascular responses in women with polycystic ovary syndrome. EUROPEAN HEART JOURNAL, 32, 171-172. 2011 Sverdlov, A. L., Ngo, D. T., Chan, W. P., Chapman, M. J., Chirkov, Y. Y., Gersh, B. J., . . . Horowitz, J. D. (2011). Progression of Early Aortic Valve Disease: Are ACE Inhibitors Protective?. CIRCULATION, 124(21), 2 pages. 2010 Nordin, B. E. C., Daly, R. M., Horowitz, J., & Metcalfe, A. V. (2010). Making too much of a weak case. BMJ, 341(7773), c4997-1.
Scopus13 WoS12 Europe PMC92010 Neil, C. J., Nguyen, T. H., Collings, S., Mahadavan, D., Kucia, A. M., Sverdlov, A., . . . Horowitz, J. D. (2010). Tako-Tsubo Cardiomyopathy: a Slowly Resolving Pancarditis. CIRCULATION, 122(21), 2 pages. 2010 Lopes, R., Alexander, J., Al-Khatib, S., Ansell, J., Diaz, R., Easton, J., . . . Wallentin, L. (2010). Apixaban for reduction in stroke and other ThromboemboLic events in Atrial Fibrillation (ARISTOTLE) trial: Design and rationale. American Heart Journal, 159(3), 331-339.
Scopus390 WoS347 Europe PMC2542010 Bansal, M., Chan, J., Leano, R., Pillans, P., Horowitz, J., & Marwick, T. (2010). Effects of perhexiline on myocardial deformation in patients with ischaemic left ventricular dysfunction. International Journal of Cardiology, 139(2), 107-112.
Scopus10 WoS7 Europe PMC62010 Horowitz, J., & Chirkov, Y. (2010). Perhexiline and hypertrophic cardiomyopathy: A new horizon for metabolic modulation. Circulation, 122(16), 1547-1549.
Scopus32 WoS30 Europe PMC202010 Sorich, M., Vitry, A., Ward, M., Horowitz, J., & McKinnon, R. (2010). Prasugrel vs. clopidogrel for cytochrome P450 2C19-genotyped subgroups: integration of the TRITON-TIMI 38 trial data. Journal of Thrombosis and Haemostasis, 8(8), 1678-1684.
Scopus91 WoS76 Europe PMC622010 Horowitz, J., Chirkov, Y., Kennedy, J., & Sverdlov, A. (2010). Modulation of myocardial metabolism: an emerging therapeutic principle. Current Opinion in Cardiology, 25(4), 329-334.
Scopus43 WoS41 Europe PMC342010 Chirkov, Y., De Sciscio, M., Sverdlov, A., Leslie, S., Sage, P., & Horowitz, J. (2010). Hydralazine does not ameliorate nitric oxide resistance in chronic heart failure. Cardiovascular Drugs and Therapy, 24(2), 131-137.
Scopus9 WoS6 Europe PMC62010 Ngo, D., Sverdlov, A., McNeil, J., & Horowitz, J. (2010). Does Vitamin D modulate asymmetric dimethylarginine and C-reactive protein concentrations?. American Journal of Medicine, 123(4), 335-341.
Scopus110 WoS95 Europe PMC732009 Kennedy, J., Hua, X., Mishra, K., Murphy, G., Rosenkranz, A., & Horowitz, J. (2009). Inhibition of calcifyin nodule formation in cultured porcine aortic valve cells by nitric oxide donors. European Journal of Pharmacology, 602(1), 28-35.
Scopus74 WoS70 Europe PMC562009 Ritchie, R., Irvine, J., Rosenkranz, A., Patel, R., Wendt, I., Horowitz, J., & Kemp-Harper, B. (2009). Exploiting cGMP-based therapies for the prevention of left ventricular hypertrophy: NO• and beyond. Pharmacology & Therapeutics, 124(3), 279-300.
Scopus52 WoS51 Europe PMC372009 Phan, T., Shivu, G., Choudhury, A., Abozguia, K., Davies, C., Naidoo, U., . . . Frenneaux, M. (2009). Multi-centre experience on the use of perhexiline in chronic heart failure and refractory angina: old drug, new hope. European Journal of Heart Failure, 11(9), 881-886.
Scopus47 WoS42 Europe PMC282009 Ngo, D., Sverdlov, A., Willoughby, S., Nightingale, A., Chirkov, Y., McNeil, J., & Horowitz, J. (2009). Determinants of occurrence of aortic sclerosis in an aging population. JACC: Cardiovascular Imaging, 2(8), 919-927.
Scopus40 WoS41 Europe PMC292009 Ngo, D., Sverdlov, A., McNeil, J., & Horowitz, J. (2009). Correlates of arterial stiffness in an ageing population: Role of asymmetric dimethylarginine. Pharmacological Research, 60(6 Sp Iss), 503-507.
Scopus15 WoS11 Europe PMC92009 Keech, A., & Horowitz, J. (2009). Cost-effectiveness Considerations of Cardiovascular Therapeutics. Heart, Lung & Circulation (Print Edition), 18(2), 118-122.
2009 Beltrame, J., & Horowitz, J. (2009). The 56th Cardiac Society of ANZ Annual Scientific Meeting: Focused Symposia on Basic and Clinical Science. Heart, Lung & Circulation (Print Edition), 18(1), 2.
Europe PMC12009 Horowitz, J., Remme, W., & Torp-Pedersen, C. (2009). Clinical trials update from the European society of cardiology congress in Munich, 2008: TIME-CHF, CARESS-in-AMI, TRITON-TIMI 38, EUROPA, AF-CHF, and ADVANCE. Cardiovascular Drugs and Therapy, 23(1), 25-29.
Scopus2 WoS1 Europe PMC12009 Rajendran, S., Willoughby, S., Chan, W., Liberts, E., Heresztyn, T., Saha, M., . . . Horowitz, J. (2009). Polycystic ovary syndrome is associated with severe platelet and endothelial dysfunction in both obese and lean subjects. Atherosclerosis, 204(2), 509-514.
Scopus89 WoS84 Europe PMC572009 Ngo, D. T. M., Sverdlov, A. L., Mcneil, J. J., & Horowitz, J. D. (2009). Low 25-hydroxyvitamin D levels are associated with elevated plasma ADMA and C-reactive protein concentrations: nexus with cardiovascular disease. EUROPEAN HEART JOURNAL, 30, 364. 2009 Beltrame, J. F., & Horowitz, J. D. (2009). The 56th Cardiac Society of ANZ Annual Scientific Meeting: Focused Symposia on Public Health. Heart Lung and Circulation, 18(2), 93.
2008 Horowitz, J., Arstall, M., Zeitz, C., & Beltrame, J. (2008). Is there still a role for treatment with β-adrenoceptor antagonists in post-myocardial infarction patients with well-preserved left ventricular systolic function?. Acute Cardiac Care (Print Edition), 10(3), 144-147.
Scopus3 Europe PMC22008 Horowitz, J., & Chirkov, Y. (2008). Identifying clopidogrel resistance during chronic therapy: The case for a biochemical approach. Thrombosis and Haemostasis, 100(4), 519-520.
Scopus2 WoS2 Europe PMC22008 Ngo, D., Stafford, I., Kelly, D., Sverdlov, A., Wuttke, R., Weedon, H., . . . Horowitz, J. (2008). Vitamin D2 supplementation induces the development of aortic stenosis in rabbits: Interactions with endothelial function and thioredoxin-interacting protein. European Journal of Pharmacology, 590(1-3), 290-296.
Scopus31 WoS35 Europe PMC232008 Sverdlov, A., Chan, W., & Horowitz, J. (2008). Management of the metabolic syndrome in cardiovascular disease. Current Treatment Options in Cardiovascular Medicine, 10(1), 27-38.
Scopus1 Europe PMC12008 Chirkov, Y., & Horowitz, J. (2008). Platelet nitric oxide resistance: Pathogenesis and clinical implications. Nitric Oxide-Biology and Chemistry, 19(Suppl 1), 58.
2008 Horowitz, J. (2008). Therapeutic range for digoxin. Australian Prescriber, 31(5), 116.
2008 Fox, K., Ford, I., Steg, P. G., Tendera, M., Ferrari, R., Grancelli, H., . . . O'Shea, J. (2008). Ivabradine for patients with stable coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a randomised, double-blind, placebo-controlled trial. The Lancet, 372(9641), 807-816.
Scopus956 Europe PMC5572007 Armstrong, P. W., Bett, N., Brieger, D., Chew, D., Dick, R., Farshid, A., . . . Medda, M. (2007). PexeLizumab for Acute ST-elevation myocardial infarction in patients undergoing primary percutaneous coronary intervention: A randomized controlled trial. JAMA, 297(1), 43-51.
Scopus402 Europe PMC2202007 Friedell, M. L., Sandler, B. J., Andriole, J. G., Martin, S. P., Cohen, M. J., & Horowitz, J. D. (2007). Carotid angioplasty and stenting is a safe and durable procedure in a community hospital. American Surgeon, 73(6), 543-546.
Scopus2 WoS1 Europe PMC12007 Inglis, S. C., Horowitz, J. D., & Stewart, S. (2007). The natural history of acute heart failure in chronic heart failure. EUROPEAN JOURNAL OF HEART FAILURE, 6(1), 65.
2007 Chirkov, Y., & Horowitz, J. (2007). Hyperglycemia and platelet function in diabetic patients: Relevance to acute myocardial ischemia and infarction. Cardiology Review, 24(12), 25-29. 2007 Chirkov, Y. (2007). Impaired tissue responsiveness to organic nitrates and nitric oxide: A new therapeutic frontier?. Pharmacology & Therapeutics, 116(2), 287-305.
Scopus80 WoS74 Europe PMC622007 Recio-Mayoral, A., Kaski, J., McMurray, J., Horowitz, J., van Veldhuisen, D., & Remme, W. (2007). Clinical Trials Update from the European Society of Cardiology Congress in Vienna, 2007: PROSPECT, EVEREST, ARISE, ALOFT, FINESSE, Prague-8, CARESS in MI and ACUITY. Cardiovascular Drugs and Therapy, 21(6), 459-465.
Scopus30 WoS21 Europe PMC202007 Horowitz, J., & Heresztyn, T. (2007). An overview of plasma concentrations of asymmetric dimethylarginine (ADMA) in health and disease and in clinical studies: Methodological considerations. Journal of Chromatography. B, Analytical Techniques in the Biomedical and Life Sciences, 851(1-2), 42-50.
Scopus97 WoS94 Europe PMC592007 Inglis, S., Herbert, M., Davies, B., Coller, J., James, H., Horowitz, J., . . . Sallustio, B. (2007). Effect of CYP2D6 metabolizer status on the disposition of the (+) and (-) enantiomers of perhexiline in patients with myocardial ischaemia. Pharmacogenetics and Genomics (Print Edition), 17(5), 305-312.
Scopus6 WoS7 Europe PMC42007 Rajendran, S., Chirkov, Y., & Horowitz, J. (2007). Potentiation of platelet responsiveness to nitric oxide by angiotensin-(1-7) is associated with suppression of superoxide release. Platelets, 18(2), 158-164.
Scopus9 WoS8 Europe PMC62007 Ashrafian, H., Horowitz, J., & Frenneaux, M. (2007). Perhexiline. Cardiovascular Drug Reviews, 25(1), 76-97.
Scopus162 WoS138 Europe PMC1012007 Liberts, E., Willoughby, S., Kennedy, J., & Horowitz, J. (2007). Effects of perhexiline and nitroglycerin on vascular, neutrophil and platelet function in patients with stable angina pectoris. European Journal of Pharmacology, 560(1), 49-55.
Scopus14 WoS15 Europe PMC82007 Ngo, D., Heresztyn, T., Mishra, K., Marwick, T., & Horowitz, J. (2007). Aortic stenosis is associated with elevated plasma levels of asymmetric dimethylarginine (ADMA). Nitric Oxide-Biology and Chemistry, 16(2), 197-201.
Scopus38 WoS36 Europe PMC262007 Worthley, M., Holmes, A., Willoughby, S., Kucia, A., Heresztyn, T., Stewart, S., . . . Horowitz, J. (2007). The deleterious effects of hyperglycemia on platelet function in diabetic patients with acute coronary syndromes - Mediation by superoxide production resolution with intensive insulin administration. Journal of the American College of Cardiology, 49(3), 304-310.
Scopus127 WoS114 Europe PMC832007 Worthley, M., Holmes, A., Willoughby, S., Kucia, A., Heresztyn, T., Stewart, S., . . . Horowitz, J. (2007). The deleterious effects of hyperglycemia on platelet function in diabetic patients with acute coronary syndromes - Mediation by superoxide production resolution with intensive insulin administration. Journal of the American College of Cardiology, 49(3), 304-310.
Scopus127 WoS114 Europe PMC832007 Inglis, S. C., Horowitz, J. D., & Stewart, S. (2007). Acute heart failure events in a cohort of elderly patients with chronic heart failure. EUROPEAN HEART JOURNAL, 28, 84. 2007 Ngo, D. T. M., Stafford, I., Wuttke, R. D., Weedon, H., Smith, M. D., Sverdlov, A. L., . . . Horowitz, J. D. (2007). Ramipril retards progression of aortic valve stenosis: association with preservation of nitric oxide effects. EUROPEAN HEART JOURNAL, 28, 513. 2007 Ngo, D. T. M., Sverdlov, A. L., Willoughby, S. R., Nightingale, A. K., Chirkov, Y. Y., Mcneil, J. J., & Horowitz, J. D. (2007). Aortic valve sclerosis is associated with impaired platelet responsiveness to nitric oxide. EUROPEAN HEART JOURNAL, 28, 513. 2006 Horowitz, J. (2006). When and why should we employ the pharmacologist?. Dialogues in Cardiovascular Medicine, 11(4), 298-305. 2006 Inglis, S., Pearson, S., Treen, S., Gallasch, T., Horowitz, J., & Stewart, S. (2006). Extending the horizon in chronic heart failure: Effects of multidisciplinary, home-based intervention relative to usual care. Circulation, 114(23), 2466-2473.
Scopus106 WoS86 Europe PMC742006 Chirkov, Y., Mishra, K., Chandy, S., Holmes, A., Kanna, R., & Horowitz, J. (2006). Loss of anti-aggregatory effects of aortic valve tissue in patients with aortic stenosis. Journal of Heart Valve Disease, 15(1), 28-33.
Scopus13 WoS14 Europe PMC122006 Horowitz, J., & Kennedy, J. (2006). Time to address the cardiac metabolic "triple whammy" - Ischemic heart failure in diabetic patients. Journal of the American College of Cardiology, 48(11), 2232-2234.
Scopus14 WoS14 Europe PMC82006 Ritchie, R., Zeitz, C., Wuttke, R., Hii, J., & Horowitz, J. (2006). Attenuation of the negative inotropic effects of metoprolol at short cycle lengths in humans - Comparison with sotalol and verapamil. Journal of the American College of Cardiology, 48(6), 1234-1241.
Scopus8 WoS8 Europe PMC62006 Mishra, K., Sage, P., Philpott, A., Zeitz, C., & Horowitz, J. (2006). Temporal trends in major angioplasty complications: technical issues and the case for on-site coronary surgery. Internal Medicine Journal, 36(7), 458-461.
Scopus2 WoS2 Europe PMC12006 Morris, R., Jones, T., Goldsworthy, S., Wagner, T., Ho, H., & Horowitz, J. (2006). Suspected DLIS interference in the dimension DGNA digoxin assay method and the clinical application of the revised digoxin target range. Therapeutic Drug Monitoring, 28(3), 454-457.
Scopus5 WoS7 Europe PMC32006 Kennedy, J., Beck-Oldach, K., McFadden-Lewis, K., Murphy, G., Wong, Y., Zhang, Y., & Horowitz, J. (2006). Effect of the anti-anginal agent, perhexiline, on neutrophil, valvular and vascular superoxide formation. European Journal of Pharmacology, 531(1-3), 13-19.
Scopus38 WoS37 Europe PMC292006 Krum, H., Jelinek, M. V., Stewart, S., Sindone, A., Atherton, J. J., Hawkes, A. L., . . . Walsh, W. (2006). Guidelines for the prevention, detection and management of people with chronic heart failure in Australia 2006. Medical Journal of Australia, 185(10), 549-556.
Scopus125 WoS103 Europe PMC662006 Bhatt, D. L., Fox, K. A. A., Hacke, W., Berger, P. B., Black, H. R., Boden, W. E., . . . Yeoman, G. D. (2006). Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. NEW ENGLAND JOURNAL OF MEDICINE, 354(16), 1706-1717.
WoS20082005 Davies, B., Coller, J., James, H., Somogyi, A., Horowitz, J., & Sallustio, B. (2005). The influence of CYP2D6 genotype on trough plasma perhexiline and cis-OH-perhexiline concentrations following a standard loading regimen in patients with myocardial ischaemia. British Journal of Clinical Pharmacology, 61(3), 321-325.
Scopus10 WoS11 Europe PMC62005 Anderson, R., Ellis, G., Evans, L., Morris, K., Chirkov, Y., Horowitz, J., . . . Frenneaux, M. (2005). Platelet nitrate responsiveness in fasting and postprandial type 2 diabetes. Diabetes and Vascular Disease Research, 2(2), 88-93.
Scopus15 Europe PMC102005 Unger, S., Kennedy, J., McFadden-Lewis, K., Minerds, K., Murphy, G., & Horowitz, J. (2005). Dissociation between metabolic and efficiency effects of perhexiline in normoxic rat myocardium. Journal of Cardiovascular Pharmacology, 46(6), 849-855.
Scopus29 WoS23 Europe PMC162005 Willoughby, S., Stewart, S., Holmes, A., Chirkov, Y., & Horowitz, J. (2005). Platelet nitric oxide responsiveness - A novel prognostic marker in acute coronary syndromes. Arteriosclerosis Thrombosis and Vascular Biology, 25(12), 2661-2666.
Scopus71 WoS65 Europe PMC562005 Lee, L., Campbell, R., Scheuermann-Freestone, M., Taylor, R., Gunaruwan, P., Williams, L., . . . Frenneaux, M. (2005). Metabolic modulation with perhexiline in chronic heart failure - a randomized, controlled trial of short-term use of a novel treatment. Circulation, 112(21), 3280-3288.
Scopus310 WoS269 Europe PMC2122005 Rajendran, S., Chirkov, Y., Campbell, D., & Horowitz, J. (2005). Angiotensin-(1-7) enhances anti-aggregatory effects of the nitric oxide donor sodium nitroprusside. Journal of Cardiovascular Pharmacology, 46(4), 459-463.
Scopus18 WoS16 Europe PMC142005 Liberts, E., Ahmed, R., & Horowitz, J. (2005). Withdrawal of intravenous glyceryl trinitrate: absence of rebound phenomena with transition to oral isoborbide dinitrate. Clinical and Experimental Pharmacology and Physiology, 32(4), 269-272.
Scopus4 WoS3 Europe PMC22005 Nightingale, A., & Horowitz, J. (2005). Aortic sclerosis: not an innocent murmur but a marker of increased cardiovascular risk. Heart, 91(11), 1389-1393.
Scopus56 WoS46 Europe PMC372005 Holmes, A., Chirkov, Y., Willoughby, S., Poropat, S., Pereira, J., & Horowitz, J. (2005). Preservation of platelet responsiveness to nitroglycerine despite development of vascular nitrate tolerance. British Journal of Clinical Pharmacology, 60(4), 355-363.
Scopus19 WoS21 Europe PMC102005 Cleland, J., Sullivan, J., Ball, S., Horowitz, J., Agoram, B., Rosser, D., . . . Burton, P. (2005). Once-monthly administration of darbepoetin alfa for the treatment of patients with chronic heart failure and anemia - A pharmacokinetic and pharmacodynamic investigation. Journal of Cardiovascular Pharmacology, 46(2), 155-161.
Scopus44 WoS39 Europe PMC332005 Worthley, M., Horowitz, J., & Zeitz, C. (2005). Lack of inotropic effect of nitric oxide on the rat myocardium. Clinical and Experimental Pharmacology and Physiology, 32(7), 526-530.
Scopus7 WoS6 Europe PMC52004 Mishra, K., Unger, S., & Horowitz, J. (2004). Salvage of acutely ischaemic myocardium: individual quantification. Internal Medicine Journal, 34(6), 364-365.
2004 Horowitz, J. (2004). Tolerance induction during therapy with long-acting nitrates: How extensive is the "collateral damage"?. Cardiovascular Drugs and Therapy, 18(1), 11-12.
Scopus8 WoS10 Europe PMC52004 Campbell, D., Zeitz, C., Esler, M., & Horowitz, J. (2004). Evidence against a major role of angiotensin converting enzyme-related carboxypeptidase (ACE2) in angiotensin peptide metabolism in the human coronary circulation. Journal of Hypertension, 22(10), 1971-1976.
Scopus81 WoS70 Europe PMC592004 Inglis, S., McLennan, S., Dawson, A., Birchmore, L., Horowitz, J., Wilkinson, D., & Stewart, S. (2004). A new solution for an old problem? Effects of a nurse-led, multidisciplinary, home-based intervention on readmission and mortality inpatients with chronic atrial fibrillation. Cardiovascular Nursing, 19(2), 118-127.
Scopus35 Europe PMC252004 DeLaLande, I., Stepien, J., Philpott, A., Hughes, P., Stafford, I., & Horowitz, J. (2004). Aldehyde dehrdrogenase, nitric oxide synthase and superoxide in ex vivo nitrate tolerance in rat aorta. European Journal of Pharmacology, 496(1), 141-149.
Scopus17 WoS16 Europe PMC152004 Philpott, A., Chandy, S., Morris, R., & Horowitz, J. (2004). Development of a regimen for rapid initiation of perhexiline therapy in acute coronary syndromes. Internal Medicine Journal, 34(6), 361-363.
Scopus7 WoS8 Europe PMC52004 Ngo, D., Wuttke, R., Turner, S., Marwick, T., & Horowitz, J. (2004). Quantitative assessment of aortic sclerosis using ultrasonic backscatter. Journal of the American Society of Echocardiography, 17(11), 1123-1130.
Scopus22 WoS24 Europe PMC182004 Beltrame, J., Turner, S., Leslie, S., Solomon, P., Freedman, S., & Horowitz, J. (2004). The angiographic and clinical benefits of mibefradil in the coronary slow flow phenomenon. Journal of the American College of Cardiology, 44(1), 57-62.
Scopus102 WoS86 Europe PMC592004 Chirkov, Y., Holmes, A., Martelli, J., & Horowitz, J. (2004). Effect of Perindopril on platelet nitric oxide resistance in patients with chronic heart failure secondary to ischemic left ventricular dysfunction. American Journal of Cardiology, 93(11), 1438-1440.
Scopus30 WoS28 Europe PMC212004 Heresztyn, T., Worthley, M., & Horowitz, J. (2004). Determination of L-arginine and NG,NG- and NG,NG'-dimethyl-L-arginine in plasma by liquid chromatography as AccQ-FluorTM fluorescent derivatives. Journal of Chromatography. B, Analytical Techniques in the Biomedical and Life Sciences, 805(2), 325-329.
Scopus90 WoS89 Europe PMC572004 DeLaLande, I., Siebert, T., Bennett, C., Stafford, I., & Horowitz, J. (2004). Influence of the endothelium on ex vivo tolerance and metabolism of glyceryl trinitrate in rat aorta. European Journal of Pharmacology, 486(2), 201-207.
Scopus7 WoS6 Europe PMC52004 Jones, T., Morris, R., & Horowitz, J. (2004). Concentration-time profile for perhexiline and hydroxyperhexiline in patients at steady state. British Journal of Clinical Pharmacology, 57(3), 263-269.
Scopus4 WoS4 Europe PMC32004 Anderson, R., Ellis, G., Chirkov, Y., Holmes, A., Payne, N., Blackman, D., . . . Frenneaux, M. (2004). Determinants of platelet responsiveness to nitric oxide in patients with chronic heart failure. European Journal of Heart Failure, 6(1), 47-54.
Scopus33 WoS42 Europe PMC212004 Zhang, Y., Oliver, J., & Horowitz, J. (2004). The role of endothelin in mediating ischemia/hypoxia-induced atrial natriuretic peptide release. Journal of Cardiovascular Pharmacology, 43(2), 227-233.
Scopus12 WoS10 Europe PMC92004 Davies, B., Coller, J., James, H., Gillis, D., Somogyi, A., Horowitz, J., . . . Sallustio, B. (2004). Clinical inhibition of CYP2D6-catalysed metabolism by the antianginal agent perhexiline. British Journal of Clinical Pharmacology, 57(4), 456-463.
Scopus6 WoS6 Europe PMC52004 Kiu, A., Horowitz, J. D., Stewart, S., & Wood, K. (2004). Seasonal variation in af‐related admissions to a coronary care unit in a “hot” climate: Fact or fiction?. Journal of Cardiovascular Nursing, 19(2), 138-141.
Scopus16 Europe PMC92004 Lee, L., Horowitz, J., & Frenneaux, M. (2004). Metabolic manipulation in ischaemic heart disease, a novel approach to treatment. European Heart Journal, 25(8), 634-641.
Scopus168 WoS136 Europe PMC962003 Shah, P., Hare, D., Raman, J., Gordon, I., Chan, R., Horowitz, J., . . . Buxton, B. (2003). Survival after myocardial revascularization for ischemic cardiomyopathy: A prospective ten-year follow-up study. Journal of Thoracic and Cardiovascular Surgery, 126(5), 1320-1327.
Scopus43 WoS33 Europe PMC272003 Zimmermann, A., Jeffries, W., McElroy, H., & Horowitz, J. (2003). Utility of a weight-based heparin nomogram for patients with acute coronary syndromes. Internal Medicine Journal, 33(1-2), 18-25.
Scopus15 WoS14 Europe PMC122003 Worthley, M., Unger, S., Mathew, T., Russ, G., & Horowitz, J. (2003). Usefulness of tachycardic-stress perfusion imaging to predict coronary artery disease in high-risk patients with chronic renal failure. American Journal of Cardiology, 92(11), 1318-1320.
Scopus23 WoS21 Europe PMC182003 Beltrame, J., Limaye, S., Wuttke, R., & Horowitz, J. (2003). Coronary hemodynamic and metabolic studies of the coronary slow flow phenomenon. American Heart Journal, 146(1), 84-90.
Scopus148 WoS119 Europe PMC842003 Zeitz, C., Campbell, D., & Horowitz, J. (2003). Myocardial uptake and biochemical and hemodynamic effects of ACE inhibitors in humans. Hypertension, 41(3), 482-487.
Scopus26 WoS20 Europe PMC162003 Stewart, S., & Horowitz, J. (2003). Specialist nurse management programmes - Economic benefits in the management of heart failure. Pharmacoeconomics, 21(4), 225-240.
Scopus31 WoS20 Europe PMC172003 Stepien, J., Prideaux, R., Willoughby, S., Chirkov, Y., & Horowitz, J. (2003). Pilot study examining the effect of cholesterol lowering on platelet nitric oxide responsiveness and arterial stiffness in subjects with isolated mild hypercholesterolaemia. Clinical and Experimental Pharmacology and Physiology, 30(7), 507-512.
Scopus21 WoS23 Europe PMC132003 Beltrame, J., Turner, S., Leslie, S., & Horowitz, J. (2003). Mibefradil: "Has the baby been thrown out with the bath water?". American Heart Journal, 146(1), E3.
Scopus1 WoS1 Europe PMC12003 Horowitz, J. (2003). Amelioration of nitrate tolerance: Matching strategies with mechanisms. Journal of the American College of Cardiology, 41(11), 2001-2003.
Scopus16 WoS5 Europe PMC62002 Willoughby, S., Stewart, S., Chirkov, Y., Kennedy, J., Holmes, A., & Horowitz, J. (2002). Beneficial clinical effects of perhexiline in patients with stable angina pectoris and acute coronary syndromes are associated with potentiation of platelet responsiveness to nitric oxide. European Heart Journal, 23(24), 1946-1954.
Scopus52 WoS46 Europe PMC382002 Beltrame, J., Limaye, S., & Horowitz, J. (2002). The coronary slow flow phenomenon - A new coronary microvascular disorder. Cardiology: international journal of cardiovascular medicine, surgery and pathology, 97(4), 197-202.
Scopus259 WoS222 Europe PMC1442002 Beltrame, J., Stewart, S., Leslie, S., Poropat, S., & Horowitz, J. (2002). Resolution of ST-segment elevation following intravenous administration of nitroglycerin and verapamil. American Journal of Cardiology, 89(4), 452-455.
Scopus8 WoS8 Europe PMC52002 Stewart, S., & Horowitz, J. (2002). Home-based intervention in congestive heart failure: Long-term implications on readmission and survival. Circulation, 105(24), 2861-2866.
Scopus257 WoS201 Europe PMC1772002 Stewart, S., & Horowitz, J. (2002). Detecting early clinical deterioration in chronic heart failure patients post-acute hospitalisation - a critical component of multidisciplinary, home-based intervention?. European Journal of Heart Failure, 4(3), 345-351.
Scopus42 WoS32 Europe PMC202002 Barraclough, D., Bertouch, J., Brooks, P., Brown, M., Cleland, L., Clemens, L., . . . Yeomans, N. (2002). Considerations for the safe prescribing and use of COX-2-specific inhibitors. Medical Journal of Australia, 176(7), 328-331.
Scopus22 WoS11 Europe PMC12002 Chirkov, Y., Holmes, A., Willoughby, S., Stewart, S., & Horowitz, J. (2002). Association of aortic stenosis with platelet hyperaggregability and impaired responsiveness to nitric oxide. American Journal of Cardiology, 90(5), 551-554.
Scopus38 WoS40 Europe PMC332002 Dudman, N., Hunt, D., MacMahon, S., Neal, B., Richards, M., Simes, J., . . . Bruning, J. (2002). Dose-dependent effects of folic acid on plasma homocysteine in a randomized trial conducted among 723 individuals with coronary heart disease. European Heart Journal, 23(19), 1509-1515.
Scopus32 Europe PMC172001 Ahuad-Guerrero, R., Basara, M., Bastianelli, R., Beloscar, J., Bono, J. O., Castellanos, R., . . . Coelho, O. R. (2001). Erratum: Effects of long-term, moderate-intensity oral anticoagulation in addition to aspirin in unstable angina (Journal of the American College of Cardiology (2000) 37 (475-484)). Journal of the American College of Cardiology, 37(3), 973.
Scopus22001 Friedell, M. L., Joseph, B. P., Cohen, M. J., & Horowitz, J. D. (2001). Surgery for carotid artery stenosis following neck irradiation. Annals of Vascular Surgery, 15(1), 13-18.
Scopus42 Europe PMC282001 Horowitz, J., & Stewart, S. (2001). Heart failure in older people: the epidemic we had to have. Medical Journal of Australia, 174(9), 432-433.
Scopus6 WoS4 Europe PMC32001 Chirkov, Y., Holmes, A., Willoughby, S., Stewart, S., Wuttke, R., Sage, P., & Horowitz, J. (2001). Stable angina and acute coronary syndromes are associated with nitric oxide resistance in platelets. Journal of the American College of Cardiology, 37(7), 1851-1857.
Scopus74 WoS61 Europe PMC502001 Ellis, G., Anderson, R., Chirkov, Y., Morris-Thurgood, J., Jackson, S., Lewis, M., . . . Frenneaux, M. (2001). Acute effects of vitamin c on platelet responsiveness to nitric oxide donors and endothelial function in patients with chronic heart failure. Journal of Cardiovascular Pharmacology, 37(5), 564-570.
Scopus46 WoS45 Europe PMC352001 Kucia, A., Taylor, K., & Horowitz, J. (2001). Can a nurse trained in coronary care expedite emergency department management of patients with acute coronary syndromes?. Heart & Lung, 30(3), 186-190.
Scopus12 WoS8 Europe PMC92001 Stewart, S., Blue, L., Capewell, S., Horowitz, J., & McMurray, J. (2001). Poles apart, but are they the same? A comparative study of Australian and Scottish patients with chronic heart failure. European Journal of Heart Failure, 3(2), 249-255.
Scopus14 WoS12 Europe PMC122001 Cleland, J., Thygesen, K., Uretsky, B., Armstrong, P., Horowitz, J., Massie, B., . . . Ryden, L. (2001). Cardiovascular critical event pathways for the progression of heart failure; A report from the ATLAS study. European Heart Journal, 22(17), 1601-1612.
Scopus57 WoS48 Europe PMC312001 Massie, B., Armstrong, P., Cleland, J., Horowitz, J., Packer, M., Poole-Wilson, P., & Ryden, L. (2001). Toleration of high doses of angiotensin-converting enzyme inhibitors in patients with chronic heart failure - Results from the ATLAS trial. Archives of Internal Medicine, 161(2), 165-171.
Scopus78 WoS62 Europe PMC462001 Beltrame, J. F., Turner, S. P., & Horowitz, J. D. (2001). Persistence of the coronary slow flow phenomenon. American Journal of Cardiology, 88(8), 938.
Scopus11 WoS10 Europe PMC72000 Chirkov, Y., Holmes, A., Chirkova, L., & Horowitz, J. (2000). Nitrate resistance in platelets from patients with stable angina pectoris - Response. Circulation, 102(11), E87. 2000 Kennedy, J., Kiosoglous, A., Murphy, G., Pelle, M., & Horowitz, J. (2000). Effect of perhexiline and oxfenicine on myocardial function and metabolism during low-flow ischemia/reperfusion in the isolated rat heart. Journal of Cardiovascular Pharmacology, 36(6), 794-801.
Scopus83 WoS70 Europe PMC542000 Sculpher, M., Poole, L., Cleland, J., Drummond, M., Armstrong, P., Horowitz, J., . . . Ryden, L. (2000). Low doses vs. high doses of the angiotensin converting-enzyme inhibitor lisinopril in chronic heart failure: a cost-effectiveness analysis based on the Assessment of Treatment with Lisinopril and Survival (ATLAS) Study. European Journal of Heart Failure, 20(2), 447-454.
Scopus36 WoS32 Europe PMC232000 Zeitz, C., Ritchie, R., Jarrett, R., Hii, J., Wuttke, R., & Horowitz, J. (2000). The positive inotropic effects of milrinone but not of digoxin are attenuated at short cycle lengths. Journal of Cardiovascular Pharmacology, 35(3), 427-433.
Scopus1 WoS1 Europe PMC12000 Kucia, A., & Horowitz, J. (2000). Is informed consent to clinical trials an "upside selective" process in acute coronoary syndromes?. American Heart Journal, 140(1), 94-97.
Scopus42 WoS34 Europe PMC202000 Uretsky, B., Thygesen, K., Armstrong, P., Cleland, J., Horowitz, J., Massie, B., . . . Ryden, L. (2000). Acute coronary findings at autopsy in heart failure patients with sudden death : results from the assessment of treatment with lisinopril and survival (ATLAS) trial. Circulation, 102(6), 611-616.
Scopus306 WoS246 Europe PMC1902000 Sage, P., DeLaLande, I., Stafford, I., Bennett, C., Phillipov, G., Stubberfield, J., & Horowitz, J. (2000). Nitroglycerin tolerance in human vessels: evidence for Impaired Nitroglycerin Bioconversion. Circulation, 102(23), 2810-2815.
Scopus140 WoS124 Europe PMC842000 Horowitz, J. (2000). Home-based intervention: the next step in treatment of chronic heart failure?. European Heart Journal, 21(22), 1807-1809.
Scopus20 WoS18 Europe PMC92000 Ryden, L., Armstrong, P., Cleland, J., Horowitz, J., Massie, B., Packer, M., & Poole-Wilson, P. (2000). Efficacy and safety of high-dose lisinopril in chronic heart failure patients at high cardiovascular risk, including those with diabetes mellitus. European Heart Journal, 21(23), 1967-1978.
Scopus144 WoS120 Europe PMC842000 Cleland, J. G. F., Armstrong, P., Horowitz, J. D., Massie, B., Packer, M., Poole-Wilson, P. A., & Rydén, L. (2000). Baseline clinical characteristics of patients recruited into the assessment of treatment with lisinopril and survival study. European Journal of Heart Failure, 1(1), 73-79.
Scopus15 WoS11 Europe PMC102000 Anderson, R. A., Ellis, G. R., Chirkov, Y. Y., Blackman, D. J., Jackson, S. K., Lewis, M. J., . . . Frenneaux, M. P. (2000). Primary nitric oxide resistance and oxidative stress in patients with chronic heart failure. Heart, 83(SUPPL. 1). 2000 Stewart, S., Marley, J. E., & Horowitz, J. D. (2000). A multidisciplinary, home based intervention reduced deaths and readmissions in patients with chronic congestive heart failure. Evidence-Based Medicine, 5(3), 84.
1999 Stewart, S., Vandenbroek, A. J., Pearson, S., & Horowitz, J. D. (1999). A home-based intervention reduced out-of-hospital deaths and hospitalizations in CHF. Evidence-Based Medicine, 4(4), 115. 1999 Horowitz, J. D. (1999). The ATLAS study: low-dose versus high-dose lisinopril in heart failure.. International journal of clinical practice. Supplement, 100, 15-16.
Europe PMC21999 Tornvall, P., Chirkova, L., Toverud, K., Horowitz, J., Chirkov, Y., & Gustaf, K. (1999). Native and oxidized low density lipoproteins enhance platelet aggregation in whole blood. Thrombosis Research, 95(4), 177-183.
Scopus5 WoS5 Europe PMC31999 Stewart, S., Marley, J., & Horowitz, J. (1999). Effects of a multidisciplinary, home-based intervention on planned readmissions and survival among patients with chronic congestive heart failure: a randomised controlled study. Lancet, 354(9184), 1077-1083.
Scopus538 WoS433 Europe PMC3251999 Kennedy, J., Mohan, P., Pelle, M., Wade, S., & Horowitz, J. (1999). The effects of perhexiline on the rat coronary vasculature. European Journal of Pharmacology, 370(3), 263-270.
Scopus3 WoS3 Europe PMC31999 de la Lande, I., Stafford, I., & Horowitz, J. (1999). Tolerance induction by transdermal glyceryl trinitrate in rats. European Journal of Pharmacology, 374(1), 71-75.
Scopus19 WoS19 Europe PMC141999 de la Lande, I., Stafford, I., & Horowitz, J. (1999). Effects of guanylyl cyclase and protein kinase G inhibitors on vasodilatation in non-tolerant and tolerant bovine coronary arteries. European Journal of Pharmacology, 370(1), 39-46.
Scopus5 WoS5 Europe PMC51999 Chirkov, Y., Holmes, A., Chirkova, L., & Horowitz, J. (1999). Nitrate Resistance in platelets from patients with stable angina pectoris. Circulation, 100(2), 129-134.
Scopus84 WoS80 Europe PMC531999 Packer, M., Poole-Wilson, P., Armstrong, P., Cleland, J., Horowitz, J., Massie, B., . . . Uretsky, B. (1999). Comparative effects of low and high doses of the angiotensin-converting enzyme inhibitor, lisinopril on morbidity and mortality in chronic heart failure. Circulation, 100(23), 2312-2318.
Scopus1147 WoS829 Europe PMC5491999 Beltrame, J. F., Horowitz, J. D., & Murakami, H. (1999). ST elevation secondary to microvascular dysfunction [4] (multiple letters). Journal of the American College of Cardiology, 34(1), 312-313.
Scopus101999 Uretsky, B. F., Cleland, J. G. F., Horowitz, J. D., Massie, B. M., Packer, M., Poole-Wilson, P. A., & Ryden, L. (1999). The effect of performing an autopsy on classifying the cause of death in patients with heart failure. CIRCULATION, 100(18), 861.
WoS11999 Uretsky, B. F., Thygesen, K., Cleland, J. G. F., Horowitz, J. D., Massie, B. M., Packer, M., . . . Ryden, L. (1999). Clinical-pathological correlation in the diagnosis of coronary disease as the cause of heart failure. CIRCULATION, 100(18), 860. 1999 Uretsky, B. F., Thygesen, K., Cleland, J. G. F., Horowitz, J. D., Massie, B. M., Packer, M., . . . Ryden, L. (1999). Causes of sudden death in heart failure patients: Results from the ATLAS trial. CIRCULATION, 100(18), 580.
WoS21999 de la Lande, I. S., Stafford, I., & Horowitz, J. D. (1999). Tolerance induction by transdermal glyceryl trinitrate in rats (vol 374, pg 71, 1999). EUROPEAN JOURNAL OF PHARMACOLOGY, 379(1), 115. 1999 Beltrame, J. F., & Horowitz, J. D. (1999). ST elevation secondary to microvascular dysfunction. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 34(1), 312-313.
WoS8 Europe PMC51999 Stewart, S., Marley, J. E., & Horowitz, J. D. (1999). Does multidisciplinary, home-based intervention reduce unplanned readmissions and prolong event-free survival among congestive heart failure patients?. CIRCULATION, 100(18), 31. 1999 De la Lande, I. S., Stafford, I., & Horowitz, J. D. (1999). Erratum: Tolerance induction by transdermal glyceryl trinitrate in rats (European Journal of Pharmacology (1999) 374 (71x-75x) PII: S0014299999003192). European Journal of Pharmacology, 379(1), 115.
1999 Saccoia, N. C., Kennedy, J. A., Horowitz, J. D., & Ruffin, R. E. (1999). Effect of amiodarone on carnitine palmitoyltransferasei activity in pulmonary tissue. Respirology, 4(SUPPL. 1). 1999 Sage, P., Kiosoglous, A., Wuttke, R., & Horowitz, J. (1999). Early treatment with verapamil or diltiazem in patients with acute myocarial infarction: safety and possible beneficial effects. Cardiovascular Drugs and Therapy, 13(4), 309-313.
Scopus2 WoS2 Europe PMC21999 Stewart, S., Vandenbroek, A., Pearson, S., & Horowitz, J. (1999). Prolonged beneficial effects of a home-based intervention on unplanned readmissions and mortality among patients with congestive heart failure. Archives of Internal Medicine, 159(3), 257-261.
Scopus226 WoS181 Europe PMC1301998 Penglis, P., Russ, G., Horowitz, J., Seymour, A., & Kirkham, B. (1998). Dilated cardiomyopathy associated with anti-neutrophil cytoplasmic antibodies. Australian and New Zealand Journal of Medicine, 28(2), 217.
WoS11998 Stewart, S., Pearson, S., & Horowitz, J. (1998). Effects of a home-based intervention among patients with congestive heart failure discharged from acute hospital care. Archives of Internal Medicine, 158(10), 1067-1072.
Scopus377 WoS300 Europe PMC2211998 Beltrame, J. F., Zeitz, C. J., Moran, J. L., Horowitz, J. D., Archbold, R. A., Cotter, G., . . . Golik, A. (1998). Nitrates for myocardial infarction (multiple letters) [2]. Lancet, 351(9117), 1731-1732.
Scopus1 Europe PMC21998 Beltrame, J. F., Limaye, S. B., Wuttke, R. D., & Horowitz, J. D. (1998). The coronary slow flow phenomenon: A small vessel disorder which presents as an acute coronary syndrome. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 31(2), 358A-359A.
WoS31998 Uretsky, B. F., Armstrong, P. W., Cleland, J. G., Horowitz, J. D., Massie, B. M., Ryden, L., . . . Poole-Wilson, P. A. (1998). Ischemia as a 'Trigger' for sudden death in patients with cardiomyopathy and heart failure secondary to coronary artery disease: Results from the ATLAS trial. CIRCULATION, 98(17), 199.
WoS61998 Zeitz, C. J., Ritchie, R. H., Jarrett, R. G., Hii, J. T. Y., & Horowitz, J. D. (1998). Mechanical restitution predicts response to tachycardia in humans. CIRCULATION, 98(17), 760. 1998 Cleland, J. G. F., Massie, B. M., Packer, M., Armstrong, P. W., Horowitz, J. D., Ryden, L., & Poole-Wilson, P. A. (1998). Health economic benefits of treating patients with heart failure with high dose lisinopril versus low dose: The ATLAS study. CIRCULATION, 98(17), 135.
WoS41998 Zhang, Y., Oliver, J., & Horowitz, J. (1998). Endothelin B receptor-mediated vasoconstriction induced by endothelin A receptor antagonist. Cardiovascular Research, 39(3), 665-673.
Scopus20 WoS22 Europe PMC151998 Kennedy, J., & Horowitz, J. (1998). Effect of trimetazidine on carnitine palmitoyltransferase-1 in the rat heart. Cardiovascular Drugs and Therapy, 12(4), 359-363.
Scopus27 WoS21 Europe PMC151998 Ritchie, R., & Horowitz, J. (1998). Elimination but not accumulation of metoprolol by rat isolated perfused heart is selectively impaired by hypoxia. Clinical and Experimental Pharmacology and Physiology, 25(August), 548-551.
Scopus1 WoS1 Europe PMC11998 Willoughby, S., Chirkov, Y., Kennedy, J., Murphy, G., Chirkova, L., & Horowitz, J. (1998). Inhibition of long-chain fatty acid metabolism does not affect platelet aggregation responses. European Journal of Pharmacology, 356(2-3), 207-213.
Scopus13 WoS14 Europe PMC71998 Ritchie, R., Sallustio, B., Hii, J., & Horowitz, J. (1998). Short-term myocardial uptake of d- and l-Sotalol in humans: relation to hemodynamic and electrophysiologic effects. Journal of Cardiovascular Pharmacology, 31(6), 876-884.
1998 Ritchie, R., Hii, J., & Horowitz, J. (1998). Relationship between myocardial milrinone content and its acute hemodynamic and electrophysiologic effects. Journal of Cardiovascular Pharmacology, 31(6), 885-893.
Scopus4 WoS5 Europe PMC41998 Beltrame, J., Zietz, C., Unger, S., Brennan, R., Hunt, A., Moran, J., & Horowitz, J. (1998). Nitrate therapy is an alternative to furosemide/morphine therapy in the management of acute cardiogenic pulmonary edema. Journal of Cardiac Failure, 4(4), 271-279.
Scopus57 Europe PMC301998 Beltrame, J., Zeitz, C., Moran, J., & Horowitz, J. (1998). Nitrates for myocardial infarction. Lancet, 351(9117), 1731-1732.
1998 Stewart, S., Pearson, S., Luke, C., & Horowitz, J. (1998). Effects of home-based intervention on unplanned readmissions and out-of-hospital deaths. Journal of the American Geriatrics Society, 46(2), 174-180.
Scopus157 WoS128 Europe PMC951998 Ritchie, R., Morgan, D., & Horowitz, J. (1998). Myocardial effect compartment modeling of metoprolol and sotalol: importance of myocardial subsite drug concentration. Journal of Pharmaceutical Sciences, 87(2), 177-182.
Scopus9 WoS9 Europe PMC71998 Stewart, S., Pearson, S., Luke, C. G., & Horowitz, J. D. (1998). A home-based intervention reduced the frequency of hospital readmissions and out-of-hospital deaths after discharge. Evidence-Based Medicine, 3(4), 122. 1998 Massie, B. M., Cleland, J. G. F., Armstrong, P. W., Horowitz, J. D., Packer, M., Poole- Wilson, P. A., & Ryden, L. (1998). Erratum: Regional differences in the characteristics and treatment of patients participating in an international heart failure trial (Journal of Cardiac Failure (1998) 4:3)). Journal of Cardiac Failure, 4(2), 153. 1998 Smith, J. R., Friedell, M. L., Cheatham, M. L., Martin, S. P., Cohen, M. J., & Horowitz, J. D. (1998). Peripherally inserted central catheters revisited. American Journal of Surgery, 176(2), 208-211.
Scopus95 WoS76 Europe PMC591998 Massie, B. M., Cleland, J. G., Armstrong, P. W., Horowitz, J. D., Packer, M., Poole-Wilson, P. A., & Ryden, L. (1998). Regional differences in the characteristics and treatment of patients participating in an international heart failure trial. The Assessment of Treatment with Lisinopril and Survival (ATLAS) Trial Investigators.. Journal of cardiac failure, 4(1), 3-8.
Europe PMC211997 Horowitz, J. D., Beltrame, J. F., Stewart, S., Wuttke, R. D., Leslie, S. L., & Poropat, S. (1997). Resolution of ST elevation in evolving acute myocardial infarction without thrombolysis. CIRCULATION, 96(8), 1443. 1997 Willoughby, S. R., Chirkova, L. P., Horowitz, J. D., & Chirkov, Y. Y. (1997). Erratum: Multiple agonist induction of aggregation: An approach to examine anti-aggregating effects in vitro (Platelets (1996) 7 (329-333)). Platelets, 8(2-3), 191.
1997 Ritchie, R. H., Zeitz, C. J., Hii, J. T., Tornvall, P., Wuttke, R., Jarrett, R., & Horowitz, J. D. (1997). Use-dependent negative inotropic effects of cardioactive agents in humans. CIRCULATION, 96(8), 4185. 1997 Zeitz, C. J., Ritchie, R. H., Hii, J. T., Horowitz, J. D., Wuttke, R. D., & Jarrett, R. (1997). Are the positive inotropic effects of digoxin and milrinone maintained at short cycle lengths?. CIRCULATION, 96(8), 4186. 1997 MacMahon, S., Sharpe, N., Doughty, R., Krum, H., Tonkin, A., Trotter, A., . . . Reid, I. (1997). Randomised, placebo-controlled trial of carvedilol in patients with congestive heart failure due to ischaemic heart disease. LANCET, 349(9049), 375-380.
WoS596 Europe PMC741997 Warner, A., & Horowitz, J. (1997). Anomalous left anterior descending coronary artery presenting with acute myocardial infarction.. Australian and New Zealand Journal of Medicine, 27(5), 594-595.
Scopus3 WoS2 Europe PMC21997 Unger, S., Robinson, M., & Horowitz, J. (1997). Perhexiline improves symptomatic status in elderly patients with severe aortic stenosis.. Australian and New Zealand Journal of Medicine, 27(1), 24-28.
Scopus43 WoS37 Europe PMC301997 Chirkov, Y., Chirkova, L., & Horowitz, J. (1997). Nitroglycerin tolerance at the platelet level in patients with angina pectoris.. American Journal of Cardiology, 80(2), 128-131.
Scopus32 WoS32 Europe PMC251997 Topol, E., Califf, R., Ohman, E., Skene, A., Wilcox, R., Grinfeld, L., . . . Ashley, B. (1997). A comparison of reteplase with alteplase for acute myocardial infarction. New England Journal of Medicine, 337(16), 1118-1123.
Scopus673 Europe PMC2681996 Topol, E., Califf, R., Granger, C., Van De Werf, F., Aylward, P., Simes, J., . . . Dedonis, J. (1996). A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes. New England Journal of Medicine, 335(11), 775-782.
Scopus799 Europe PMC3271996 Kennedy, J., Unger, S., & Horowitz, J. (1996). Inhibition of carnitine palmitoyltransferase-1 in rat heart and liver by perhexiline and amiodarone.. Biochemical Pharmacology, 52(2), 273-280.
Scopus191 WoS168 Europe PMC1251996 Chan, R., Raman, J., Lee, K., Rosalion, A., Hicks, R., Pornvilawan, S., . . . Buxton, B. (1996). Prediction of outcome after revascularization in patients with poor left ventricular function. Annals of Thoracic Surgery, 61(5), 1428-1434.
Scopus39 Europe PMC261996 Simon, K., Szepvolgyi, A., Arstall, M. A., Stafford, I., & Horowitz, J. D. (1996). N-acetylcysteine in combination with nitroglycerin and streptokinase for the treatment of evolving acute myocardial infarction: Safety and biochemical effects [8]. Circulation, 94(7), 1791.
Scopus2 WoS1 Europe PMC11996 Chirkov, Y., & Horowitz, J. (1996). N-acetylcysteine potentiates nitroglycerin-induced reversal of platelet aggregation.. Journal of Cardiovascular Pharmacology, 28(3), 375-380.
Scopus22 WoS19 Europe PMC141996 Stewart, S., Voss, D., Northey, D., & Horowitz, J. (1996). Relationship between plasma perhexiline concentration and symptomatic status during short-term perhexiline therapy.. Therapeutic Drug Monitoring, 18(6), 635-639.
Scopus30 WoS28 Europe PMC231996 Willoughby, S., Chirkova, L., Horowitz, J., & Chirkov, Y. (1996). Multiple agonist induction of aggregation: an approach to examine anti-aggregating effects in vitro. Platelets, 7(5-6), 329-333.
Scopus6 WoS6 Europe PMC51996 Chirkov, Y., Chirkova, L., & Horowitz, J. (1996). Suppressed anti-aggregating and cGMP-elevating effects of sodium nitroprusside in platelets from patients with stable angina pectoris. Naunyn-Schmiedeberg's Archives of Pharmacology, 354(4), 520-525.
Scopus22 WoS24 Europe PMC161996 de la Lande, I., Philp, T., Stafford, I., & Horowitz, J. (1996). Lack of inhibition of glyceryl trinitrate by diphenyleneiodonium in bovine coronary artery.. European Journal of Pharmacology, 314(3), 347-350.
Scopus4 WoS4 Europe PMC41996 de la Lande, I., Stafford, I., & Horowitz, J. (1996). Heterogeneity of glyceryl trinitrate response in isolated bovine coronoary arteries. European Journal of Phamacology, 318(1), 65-71.
Scopus3 WoS2 Europe PMC21996 Yang, J., Stafford, I., Arstall, M. A., & Horowitz, J. D. (1996). Effects of N-acetylcysteine on oxidation stress in patients with acute myocardial infarction. Chinese Journal of Cardiology, 24(4), 282-284.
Scopus11995 Zhang, Y., Ritchie, R., & Horowitz, J. (1995). Postextrasystolic potentiation in patients with ischaemic heart disease: influence of inotropic agents.. British Journal of Clinical Pharmacology, 40(1), 25-30.
Scopus2 WoS1 Europe PMC11995 Arstall, M., Yang, J., Stafford, I., Betts, W., & Horowitz, J. (1995). N-acetylcysteine in combination with nitroglycerin and streptokinase for the treatment of evolving acute myocardial infarction. Circulation, 92(10), 2855-2862.
Scopus144 WoS134 Europe PMC921995 Zhang, C., de la Lande, I., & Horowitz, J. (1995). Effects of glyceryl trinitrate tolerance on vascular responsiveness to constrictor agents in bovine isolated coronary artery. Clinical Pharmacology and Physiology, 22(5), 324-329.
Scopus3 WoS2 Europe PMC31995 KRUM, H., TONKIN, A., TROTTER, A., BURTON, R., GARRETT, J., LANE, G., . . . REID, I. (1995). EFFECTS OF CARVEDILOL, A VASODILATOR-BETA-BLOCKER, IN PATIENTS WITH CONGESTIVE-HEART-FAILURE DUE TO ISCHEMIC-HEART-DISEASE. CIRCULATION, 92(2), 212-218.
WoS199 Europe PMC201995 Ritchie, R., Wuttke, R., Hii, J., Jarrett, R., Carey, A., & Horowitz, J. (1995). The force-interval relationship of the left ventricle: a quantitative description in patients with ischemic heart disease. Journal of Cardiac Failure, 1(4), 273-284.
Scopus2 Europe PMC31995 Horowitz, J. D., Button, I. K., & Wing, L. (1995). Is perhexiline essential for the optimal management of angina pectoris?. Australian and New Zealand Journal of Medicine, 25(2), 111-113.
Scopus24 WoS21 Europe PMC141995 Chirkov, Y. Y., Chirkova, L. P., Edward Sage, R., & Horowitz, J. D. (1995). Impaired responsiveness of platelets from patients with stable angina pectoris to antiaggregating and cyclicAMP-elevating effects of prostaglandin E<inf>1</inf>. Journal of Cardiovascular Pharmacology, 25(6), 961-966.
Scopus25 WoS24 Europe PMC151995 Arstall, M. A., Stewart, S., Haste, M. A., & Horowitz, J. D. (1995). Streptokinase-induced transient aggravation of myocardial injury. International Journal of Cardiology, 50(2), 107-116.
Scopus1 WoS2 Europe PMC11995 Tonkin, A., Aylward, P., Colquhoun, D., Glasziou, P., Harris, P., Hunt, D., . . . Quinn, K. (1995). Design features and baseline characteristics of the LIPID (long-term intervention with pravastatin in ischemic disease) study: A randomized trial in patients with previous acute myocardial infarction and/or unstable angina pectoris. The American Journal of Cardiology, 76(7), 474-479.
Scopus113 Europe PMC251994 Zhang, C. L., De la Lande, I. S., Stafford, I., & Horowitz, J. D. (1994). S-nitrosothiol modulation of tolerance to glyceryl trinitrate in bovine isolated coronary artery. European Journal of Pharmacology, 252(3), 299-304.
Scopus5 WoS5 Europe PMC41994 Ritchie, R. H., Wuttke, R. D., Stafford, I., & Horowitz, J. D. (1994). Relation between acute myocardial uptake and hemodynamic and electrocardiograpic effects of metoprolol in humans. Journal of Cardiovascular Pharmacology, 23(1), 57.
Scopus7 WoS6 Europe PMC51994 Zhang, C. L., Wilson, K. M., Stafford, I., Bochner, F., & Horowitz, J. D. (1994). Absorption Kinetics of Low Dose Aspirin in Patients with Evolving Acute Myocardial Infarction. Drug Investigation, 7(4), 169-174.
Scopus8 WoS61994 Arstall, M. A., Wuttke, R. D., Arthur, J., Whitford, J. A., & Horowitz, J. D. (1994). The prevalence of ST-segment depression on ambulatory electrocardiographic monitoring during daily life in high-risk asymptomatic police officers. European Journal of Cardiovascular Prevention & Rehabilitation, 1(2), 143-148.
Scopus2 Europe PMC11994 Arstall, M. A., Barrowman, F. A., & Horowitz, J. D. (1994). Silent ischemia after uncomplicated myocardial infarction: lack of incremental clinical significance. International Journal of Cardiology, 45(1), 45-52.
Scopus1 WoS11993 ARSTALL, M. A., BARROWMAN, F. A., & HOROWITZ, J. D. (1993). Silent myocardial ischaemia is uncommon after uncomplicated acute myocardial infarction. Australian and New Zealand Journal of Medicine, 23(1), 53-54.
1993 Chirkov, Y. Y., Naujalis, J. I., Edward Sage, R., & Horowitz, J. D. (1993). Antiplatelet effects of nitroglycerin in healthy subjects and in patients with stable angina pectoris. Journal of Cardiovascular Pharmacology, 21(3), 384-389.
Scopus50 WoS45 Europe PMC251993 Meredith, I. T., Alison, J. F., Zhang, F. M., Horowitz, J. D., & Harper, R. W. (1993). Captopril potentiates the effects of nitroglycerin in the coronary vascular bed. Journal of the American College of Cardiology, 22(2), 581-587.
Scopus22 WoS20 Europe PMC161993 Chirkov, Y., Gee, D., Naujalis, J., Sage, R., & Horowitz, J. (1993). Reversal of ADP-induced platelet aggregation by S-nitrosothiols, nitroglycerine and nitroglycerine/N-acetylcysteine. Pharmacology Communications, 3(2), 97-105.
Scopus61992 Horowitz, J. D. (1992). Role of nitrates in unstable angina pectoris. The American Journal of Cardiology, 70(8), B64-B71.
Scopus22 WoS18 Europe PMC81992 Chirkov, Y. Y., Naujalis, J. I., Barber, S., Sage, R. E., Gove, D. W., Brealey, J. K., & Horowitz, J. D. (1992). Reversal of human platelet aggregation by low concentrations of nitroglycerin in vitro in normal subjects. The American Journal of Cardiology, 70(7), 802-806.
Scopus31 WoS27 Europe PMC211992 Arstall, M. A., Hii, J. T. Y., Lehman, R. G., & Horowitz, J. D. (1992). Sotalol-induced torsade de pointes: Management with magnesium infusion. Postgraduate Medical Journal, 68(798), 289-290.
Scopus19 WoS12 Europe PMC81992 Sallustio, B., Morris, R., & Horowitz, J. (1992). High-performance liquid chromatographic determination of sotalol in plasma. I. Application to the disposition of sotalol enantiomers in humans.. Journal of chromatography, 576(2), 321-327.
Europe PMC101992 Arstall, M. A., Beltrame, J. F., Mohan, P., Wuttke, R. D., Esterman, A. J., & Horowitz, J. D. (1992). Incidence of adverse events during treatment with verapamil for suspected acute myocardial infarction. The American Journal of Cardiology, 70(20), 1611-1612.
Scopus7 WoS7 Europe PMC51992 Sallustio, B. C., Morris, R. G., & Horowitz, J. D. (1992). High-performance liquid chromatographic determination of sotalol in plasma. I. Application to the disposition of sotalol enantiomers in humans. Journal of Chromatography B: Biomedical Sciences and Applications, 576(2), 321-327.
Scopus25 WoS191991 Mohan, P., Hii, J. T. Y., Wuttke, R. D., Esterman, A. J., Hollington, P., & Horowitz, J. D. (1991). Acute heart failure: determinants of outcome. International Journal of Cardiology, 32(3), 365-375.
Scopus15 WoS16 Europe PMC111991 Horowitz, J. D. (1991). Thiol-containing agents in the management of unstable angina pectoris and acute myocardial infarction. The American Journal of Medicine, 91(3 SUPPL. 3), S113-S117.
Scopus8 WoS5 Europe PMC11991 Chirkov, Y. Y., Belushkina, N. N., Tyshchuk, I. A., Severina, I. S., & Horowitz, J. D. (1991). INCREASE IN REACTIVITY OF HUMAN PLATELET GUANYLATE CYCLASE DURING AGGREGATION POTENTIATES THE DISAGGREGATING CAPACITY OF SODIUM NITROPRUSSIDE. Clinical and Experimental Pharmacology and Physiology, 18(7), 517-524.
Scopus19 WoS23 Europe PMC101990 Henry, P. J., Horowitz, J. D., & Louis, W. J. (1990). Nitrate tolerance induced by nicorandil or nitroglycerin is associated with minimal loss of nicorandil vasodilator activity. Journal of Cardiovascular Pharmacology, 15(3), 365-370.
Scopus20 Europe PMC121990 Powell, A. C., Horowitz, J. D., Hasin, Y., & Louis, W. J. (1990). RELATIONSHIP BETWEEN SYSTEMIC AND CORONARY VASCULAR RESPONSES TO DIGOXIN AND CONCURRENT DRUG THERAPY WITH VERAPAMIL/β‐ADRENOCEPTOR ANTAGONISTS IN HUMANS. Clinical and Experimental Pharmacology and Physiology, 17(6), 453-462.
Scopus11990 Powell, A. C., Horowitz, J. D., Kertes, P. J., Hasin, Y., Syrjanen, M. L., Henry, C. A., . . . Louis, W. J. (1990). Determinants of acute hemodynamic and electrophysiologic effects of verapamil in humans: Role of myocardial drug uptake. Journal of Cardiovascular Pharmacology, 16(4), 572-583.
Scopus11 Europe PMC81990 Powell, A. C., Horowitz, J. D., Hasin, Y., Syrjanen, M. L., Horomidis, S., & Louis, W. J. (1990). Acute myocardial uptake of digoxin in humans: Correlation with hemodynamic and electrocardiographic effects. Journal of the American College of Cardiology, 15(6), 1238-1247.
Scopus19 Europe PMC151989 Henry, P. J., Horowitz, J. D., & Louis, W. J. (1989). Nitroglycerin-induced tolerance affects multiple sites in the organic nitrate bioconversion cascade. Journal of Pharmacology and Experimental Therapeutics, 248(2), 762-768.
Scopus64 Europe PMC401989 Morgan, D. J., Horowitz, J. D., & Louis, W. J. (1989). Prediction of acute myocardial disposition of antiarrhythmic drugs. Journal of Pharmaceutical Sciences, 78(5), 384-388.
Scopus5 Europe PMC21989 Henry, P. J., Drummer, O. H., & Horowitz, J. D. (1989). S-nitrosothiols as vasodilators: Implications regarding tolerance to nitric oxide-containing vasodilators. British Journal of Pharmacology, 98(3), 757-766.
Scopus61 Europe PMC491989 Sewell, R. B., Horowitz, J. D., Grinpukel, S. A., & Martin, G. (1989). PERHEXILENE: EFFECTS ON HEPATIC LYSOSOMAL FUNCTION IN RATS. Clinical and Experimental Pharmacology and Physiology, 16(1), 25-32.
Scopus4 Europe PMC21989 Henry, P. J., Horowitz, J. D., & Louis, W. J. (1989). Determinants of in vitro nitroglycerin tolerance induction and reversal: Influence of dose regimen, nitrate-free period, and sulfhydryl supplementation. Journal of Cardiovascular Pharmacology, 14(1), 31-37.
Scopus33 Europe PMC211989 Phillips, P., Sasadeus, J., Hodsman, G., Horowitz, J., Saltups, A., & Johnston, C. (1989). Plasma atrial natriuretic peptide in patients with acute myocardial infarction: effects of streptokinase. British Heart journal, 61(2), 139-143.
Scopus28 Europe PMC201989 Horowitz, J. D., & Powell, A. C. (1989). Calcium antagonist drugs in the management of cardiovascular disease: Current status. Medical Journal of Australia, 150(10), 591-595.
Scopus10 Europe PMC31988 Horowitz, J. D., Henry, C. A., Syrjanen, M. L., Louis, W. J., Fish, D., Smith, T. W., & Antman, E. M. (1988). Combined use of nitroglycerin and N-acetylcysteine in the management of unstable angina pectoris. Circulation, 77(4), 787-794.
Scopus100 Europe PMC641988 Powell, A. C., Elliott, S. L., & Horowitz, J. D. (1988). Verapamil in unstable angina pectoris: Failure to demonstrate a relationship between efficacy and plasma levels. Therapeutic Drug Monitoring, 10(1), 34-38.
Scopus5 Europe PMC31988 Horowitz, J. D., Henry, C. A., Syrjanen, M. L., Louis, W. J., Fish, R. D., Antman, E. M., & Smith, T. W. (1988). Nitroglycerin/N-acetylcysteine in the management of unstable angina pectoris. European Heart Journal, 9(SUPPL. A), 95-100.
Scopus14 Europe PMC61988 Lee, K. J., Horowitz, J. D., McKay, W. J., & Goble, A. J. (1988). Myocardial salvage with streptokinase combined with nitroglycerine and verapamil in acute myocardial infarction. International Journal of Cardiology, 21(3), 279-291.
Scopus7 Europe PMC41987 Sia, S., Horowitz, J., & Goble, A. (1987). Non-Q-wave infarction: Prognostic value of exercise test results. Cardiology Board Review, 4(1), 59-64. 1987 Smith, G. L., Horowitz, J. D., & Henry, P. J. (1987). Nitrate therapy of ischaemic heart disease. Medical Journal of Australia, 146(11), 607-609.
1987 Horowitz, J. D., & Henry, P. J. (1987). Recent developments in nitrate therapy of ischaemic heart disease. Medical Journal of Australia, 146(2), 93-96.
Scopus8 Europe PMC81987 Thatcher, R. L., Butty, J. S., Whitworth, J. A., Hunt, V. D. U., Shaw, P. F., Skinner, S. L., & Horowitz, J. D. (1987). Potential functions of plasma prorenin; regional activation and tissue extraction. Clinical and Experimental Hypertension, A9(8-9), 1415-1434.
Scopus8 Europe PMC31986 Horowitz, J. D., Sia, S. T. B., Macdonald, P. S., Goble, A. J., & Louis, W. J. (1986). Perhexiline maleate treatment for severe angina pectoris - correlations with pharmacokinetics. International Journal of Cardiology, 13(2), 219-229.
Scopus107 Europe PMC831986 Skinner, S. L., Thatcher, R. L., Whitworth, J. A., & Horowitz, J. D. (1986). EXTRACTION OF PLASMA PRORENIN BY HUMAN HEART. The Lancet, 327(8488), 995-997.
Scopus24 Europe PMC131986 Drummer, O. H., Christophidis, N., Horowitz, J. D., & Louis, W. J. (1986). Measurement of penicillamine and N-acetylcysteine in human blood by high-performance liquid chromatography and electrochemical detection. Journal of Chromatography B: Biomedical Sciences and Applications, 374(C), 251-257.
Scopus21 Europe PMC81986 Horowitz, J. D., & Powell, A. C. (1986). Myocardial Uptake of Drugs and Clinical Effects. Clinical Pharmacokinetics, 11(5), 354-371.
Scopus26 Europe PMC201986 Horowitz, J. D., Dynon, M. K., Woodward, E., Sia, S. T., Macdonald, P. S., Morgan, D. J., . . . Louis, W. J. (1986). Short-term myocardial uptake of lidocaine and mexiletine in patients with ischemic heart disease. Circulation, 73(5), 987-996.
Scopus281986 Sia, S. T. B., MacDonald, P. S., Horowitz, J. D., Goble, A. J., & Doyle, A. E. (1986). Usefulness of early exercise testing after non-Q-wave myocardial infarction in predicting prognosis. The American Journal of Cardiology, 57(10), 738-744.
Scopus26 Europe PMC191986 Hare, D. L., & Horowitz, J. D. (1986). Verapamil hepatotoxicity: A hypersensitivity reaction. American Heart Journal, 111(3), 610-611.
Scopus12 Europe PMC51985 Sia, S. T. B., MacDonald, P. S., Triester, B., Oliver, L. E., Horowitz, J. D., & Goble, A. J. (1985). Aggravation of myocardial ischaemia by nifedipine. Medical Journal of Australia, 142(1), 48-50.
Scopus18 Europe PMC111985 Kern, M. J., Horowitz, J. D., Ganz, P., Gaspar, J., Colucci, W. S., Lorell, B. H., . . . Mudge, G. H. (1985). Attenuation of coronary vascular resistance by selective alpha<inf>1</inf>,-adrenergic blockade in patients with coronary artery disease. Journal of the American College of Cardiology, 5(4), 840-846.
Scopus36 Europe PMC271985 Torresi, J., Horowitz, J. D., & Dusting, G. J. (1985). Prevention and reversal of tolerance to nitroglycerine with N-acetylcysteine. Journal of Cardiovascular Pharmacology, 7(4), 777-783.
Scopus100 Europe PMC661985 Barry, W. H., Horowitz, J. D., & Smith, T. W. (1985). Comparison of negative inotropic potency, reversibility, and effects on calcium influx of six calcium channel antagonists in cultured myocardial cells. British Journal of Pharmacology, 85(1), 51-59.
Scopus43 Europe PMC291985 Kern, M. J., Horowitz, J. D., Ganz, P., Gaspar, J., Colucci, W. S., Lorell, B. H., . . . Mudge, G. H. (1985). Attenuation of coronary vascular resistance by selective alpha<inf>1</inf>-adrenergic blockade in patients with coronary artery disease. Journal of the American College of Cardiology, 5(4), 840-846.
Scopus71984 Horowitz, J. D., Dynon, M. K., Jarrott, B., Brennan, J. B., Oliver, L. E., Goble, A. J., & Louis, W. J. (1984). HAEMODYNAMIC EFFECTS OF A SINGLE LOW DOSE OF PRAZOSIN IN PATIENTS WITH CHRONIC CONGESTIVE CARDIAC FAILURE CORRELATIONS WITH PHARMACOKINETICS. Clinical and Experimental Pharmacology and Physiology, 11(1), 7-15.
Scopus1 Europe PMC21984 GOBLE, A. J., & HOROWITZ, J. D. (1984). PERHEXILENE NEUROPATHY: A REPORT OF TWO CASES. Australian and New Zealand Journal of Medicine, 14(3), 279.
Scopus4 Europe PMC31983 Horowitz, J. D. (1983). Drugs that induce heart problems. Which agents? What effects?. Journal of Cardiovascular Medicine, 8(3), 308-315. 1983 Nayler, W. G., & Horowitz, J. D. (1983). Calcium antagonists: A new class of drugs. Pharmacology and Therapeutics, 20(2), 203-262.
Scopus95 Europe PMC681983 Horowitz, J. D., Antman, E. M., Lorell, B. H., Barry, W. H., & Smith, T. W. (1983). Potentiation of the cardiovascular effects of nitroglycerin by N-acetylcysteine. Circulation, 68(6), 1247-1253.
Scopus1741983 Kern, M. J., Ganz, P., Horowitz, J. D., Gaspar, J., Barry, W. H., Lorell, B. H., . . . Mudge, G. H. (1983). Potentiation of coronary vasoconstriction by beta-adrenergic blockade in patients with coronary artery disease. Circulation, 67(6 I), 1178-1184.
Scopus151 Europe PMC1061982 Horowitz, J. D., White, H. D., & Goble, A. J. (1982). Liver disease induced by perhexiline maleate.. The Medical journal of Australia, 2(1), 9-10.
Scopus2 Europe PMC21982 Horowitz, J. D., Barry, W. H., & Smith, T. W. (1982). Lack of interaction between digoxin and quinidine in cultured heart cells. Journal of Pharmacology and Experimental Therapeutics, 220(3), 488-493.
Scopus9 Europe PMC71982 Horowitz, J. D., Barry, W. H., & Smith, T. W. (1982). Calcium channel blockade by perhexiline maleate and its M<inf>1</inf> metabolite. Journal of Molecular and Cellular Cardiology, 14(Suppl. 2), 8.
Scopus41981 Horowitz, J. D., Morris, P. M., Drummer, O., Goble, A. J., & Louis, W. J. (1981). Saturable metabolism of perhexiline maleate: Correlations with long-term toxicity. American Journal of Cardiology, 47(2 II), 399.
Scopus81981 Horowitz, J. D., Brennan, J. B., Oliver, L. E., Harding, D., Goble, A. J., & Louis, W. J. (1981). Effects of captopril (SQ 14,225) in a patient with primary pulmonary hypertension. Postgraduate Medical Journal, 57(664), 115-116.
Scopus11 Europe PMC91981 Horowitz, J. D., Anavekar, S. N., Morris, P. M., Goble, A. J., Doyle, A. E., & Louis, W. J. (1981). Comparative trial of mexiletine and lignocaine in the treatment of early ventricular tachyarrhythmias after acute myocardial infarction. Journal of Cardiovascular Pharmacology, 3(3), 409-419.
Scopus24 Europe PMC171981 Horowitz, J. D., Goble, A. J., Morris, P. M., Drummer, O. H., & Louis, W. J. (1981). High‐performance liquid chromatographic assay of perhexiline maleate in plasma. Journal of Pharmaceutical Sciences, 70(3), 320-322.
Scopus39 Europe PMC251980 Oliver, L. E., Horowitz, J. D., Dynon, M. K., Jarrott, B., Brennan, J. B., Goble, A. J., & Louis, W. J. (1980). Use of dopamine and prazosin combined in the treatment of cardiogenic shock. Medical Journal of Australia, 2(1 SPEC SUPPL), 42-45.
Scopus4 Europe PMC31980 Horowitz, J. D., & Mashford, M. L. (1980). Purification of a Peptide with Venoconstrictor and Vasodepressor Activity, from Cohn Fraction III‐O of Human Plasma Protein. Vox Sanguinis, 38(5), 259-265.
1980 Horowitz, J. D., Howes, L. G., Christophidis, N., Lang, W. J., Fennessy, M. R., Rand, M. T., & Louis, W. J. (1980). HYPERTENSIVE RESPONSES INDUCED BY PHENYLPROPANOLAMINE IN ANORECTIC AND DECONGESTANT PREPARATIONS. The Lancet, 315(8159), 60-61.
Scopus80 Europe PMC541980 Horowitz, J. D., & Mashford, M. L. (1980). Venoconstrictor Activity of Some Precursor Fractions of Stable Plasma Protein Solution. Vox Sanguinis, 38(5), 266-271.
Scopus1 Europe PMC11980 Horowitz, J., Morris, P., Goble, A., & Louis, W. (1980). Plasma levels of perhexiline maleate during treatment of patients with angina pectoris. Australian and New Zealand Journal of Medicine, 10(3), 376. 1980 Goble, A. J., Horowitz, J. D., & Morris, P. (1980). A comparative trial of mexiletine and lignocaine in the treatment of ventricular tachyarrhythmias after acute myocardial infarction. Australian and New Zealand Journal of Medicine, 10(3), 392-393.
Scopus11980 Brennan, J., Dynon, M., & Horowitz, J. (1980). Comparison of the acute haemodynamic effects and pharmacokinetic properties of prazosin in patients with stable congestive cardiac failure. Australian and New Zealand Journal of Medicine, 10(3), 375.
Scopus11980 Horowitz, J., Morris, P., Goble, A., & Louis, W. (1980). Pharmacokinetics of perhexiline maleate in patients with angina pectoris. Clinical and Experimental Pharmacology and Physiology, 7(6), 679-680.
Scopus11979 Horowitz, J., Anavekar, S., & Morris, P. (1979). Plasma levels of mexiletine in patients treated for acute and chronic ventricular tachyarrhythmias. Clinical and Experimental Pharmacology and Physiology, 6(6), 651-652.
Scopus11979 Horowitz, J. D., McNeil, J. J., Sweet, B., Mendelsohn, F. A., & Louis, W. J. (1979). Hypertension and postural hypotension induced by phenylpropanolamine (Trimolets). Medical Journal of Australia, 1(5), 175-176.
Scopus25 Europe PMC101979 Horowitz, J. D., & Goble, A. J. (1979). Drugs and Impaired Male Sexual Function. Drugs, 18(3), 206-217.
Scopus57 Europe PMC341979 Horowitz, J. D., & Mashford, M. L. (1979). Long-term safety of perhexiline maleate. Medical Journal of Australia, 1(6), 232.
Scopus2 Europe PMC11979 Horowitz, J. D., & Mashford, M. L. (1979). Perhexiline maleate in the treatment of severe angina pectoris. Medical Journal of Australia, 1(11), 485-488.
Scopus22 Europe PMC121979 Horowitz, J. D., & Mashford, M. L. (1979). Venoconstrictor activity of some precursor fractions of stable plasma protein solution (SPPS). Clinical and Experimental Pharmacology and Physiology, 6(6), 661-662. 1977 Horowitz, J., & Mashford, M. (1977). Purification of a vasodilator peptide in Cohn fraction III O of human plasma proteins. Clinical and Experimental Pharmacology and Physiology, 4(2), 199-200. 1977 Mashford, M., & Horowitz, J. (1977). Perhexiline maleate, a new anti anginal drug. Clinical and Experimental Pharmacology and Physiology, 4(2), 206. 1977 Horowitz, J., & Mashford, M. (1977). Effects of prostaglandins on an isolated blood vessel. Clinical and Experimental Pharmacology and Physiology, 4(2), 197-198. 1976 Brown, M. J., Horowitz, J. D., & Mashford, M. L. (1976). A double blind trial of perhexiline maleate in the prophylaxis of angina pectoris. Medical Journal of Australia, 1(9), 260-263.
Scopus15 Europe PMC101976 Horowitz, J. D., & Mashford, M. L. (1976). A vasodepressor peptide in Cohn fraction III-O of human plasma proteins.. Advances in Experimental Medicine and Biology, 70(0), 15-21.
Scopus3 Europe PMC11970 Horowitz, J. D., Mashford, M. L., & Nunn, M. (1970). Sex differences in level of a vasoactive plasma protein and changes during pregnancy. Experientia, 26(7), 790-791.
1969 HOROWITZ, J. D., & MASHFORD, M. L. (1969). Bradykinin antagonism by dimethothiazine. Journal of Pharmacy and Pharmacology, 21(1), 51-53.
Scopus4 Europe PMC21969 Horowitz, J. D., & Mashford, M. L. (1969). A perfused vein preparation sensitive to plasma kinins. Naunyn-Schmiedebergs Archiv für Pharmakologie und Experimentelle Pathologie, 263(2), 332-339.
Scopus10 Europe PMC31969 Horowitz, J. D., & Mashford, M. L. (1969). The action of adrenal steroids on the pharmacological reactivity of the isolated vein of the rabbit ear. Naunyn-Schmiedebergs Archiv für Pharmakologie und Experimentelle Pathologie, 263(2), 324-331.
Scopus4 Europe PMC11968 Horowitz, J. D., & Mashford, M. L. (1968). Vasoactivity of human plasma and plasma protein fractions. Experientia, 24(11), 1126-1127.
Scopus5 Europe PMC6 -
Books
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Book Chapters
Year Citation 2022 Kucia, A. M., & Horowitz, J. D. (2022). Pathogenesis of acute coronary syndromes. In Cardiac Care: A Practical Guide for Nurses (pp. 207-215). Wiley.
2013 Opie, L. H., & Horowitz, J. D. (2013). Nitrates and newer antianginals. In Drugs for the Heart: Expert Consult - Online and Print (pp. 38-63). Elsevier.
Scopus42010 Chirkov, Y., Sverdlov, A., & Horowitz, J. (2010). Beneficial clinical effects of perhexiline in cardiac patients: Multiple biochemical mechanisms. In Horizons in World Cardiovascular Research Vol. 2, 2010 (pp. 1-27). NOVA Science Publishers. 2010 Rajendran, S., Chan, W., & Horowitz, J. (2010). Insulin resistance: Relationship with polycystic ovary syndrome. In Insulin Resistance: Symptoms, Causes and Treatment (pp. 45-78). 2008 Opie, L. H., & Horowitz, J. D. (2008). β-Blocking Agents. In Drugs for the Heart (pp. 1-37). Elsevier.
Scopus12008 Opie, L. H., & Horowitz, J. D. (2008). Nitrates and Newer Antianginals. In Drugs for the Heart (pp. 38-58). Elsevier.
2008 Opie, L. H., & Horowitz, J. D. (2008). Nitrates and Newer Antianginals. In Drugs for the Heart: Expert Consult - Online and Print (pp. 38-58).
2008 Opie, L. H., & Horowitz, J. D. (2008). β-Blocking Agents. In Drugs for the Heart: Expert Consult - Online and Print (pp. 1-37).
2004 Beltrame, J. F., & Horowitz, J. D. (2004). The Management of Acute Cardiogenic Pulmonary Oedema. In S. Stewart, D. K. Moser, & D. R. Thompson (Eds.), Caring for the Heart Failure Patient: A Textbook for the Health Care Professional. (pp. 93-101). London: Martin Dunitz. 2000 Horowitz, J. (2000). Nitrovasodilators. In J. Loscalzo, & J. Vita (Eds.), Nitric Oxide and the Cardiovascular System (pp. 383-409). New Jersey, USA: Humana Press. -
Conference Papers
Year Citation 2023 Velagic, A., Li, J. C., Qin, C. X., Li, M., Deo, M., Marshall, S., . . . Ritchie, R. H. (2023). Therapeutic implications of nitroxyl (HNO) donors as a means of enhancing cGMP-mediated cardioprotection in the insulin-resistant diabetic myocardium. In JOURNAL OF TRANSLATIONAL MEDICINE Vol. 21 (pp. 1 page). Augsburg, Germany: BMC.
2022 Kelly, C., Chu, M., Untaru, R., Assadi-Khansari, B., Chen, D., Croft, A., . . . Ngo, D. T. M. (2022). Heart failure is associated with low circulating levels of secreted frizzled receptor protein 5 (Sfrp5). In EUROPEAN HEART JOURNAL Vol. 43 (pp. 918). OXFORD UNIV PRESS. 2021 Chen, D., Untaru, R., Liu, S., Assadi-Khansari, B., Croft, A., Kelly, C., . . . Sverdlov, A. (2021). Follistatin-like 3 (FSTL3) levels are increased in acute heart failure patients. In EUROPEAN HEART JOURNAL Vol. 42 (pp. 1039). OXFORD UNIV PRESS. 2019 Visvanathan, V., Kucia, A., Reddi, B., & Horowitz, J. (2019). Takotsubo Syndrome Identified in the Intensive Care Unit: A Prospective Observational Study. In AUSTRALIAN CRITICAL CARE Vol. 32 (pp. S17). ELSEVIER SCIENCE INC.
2018 Goh, V. J. K., Woolley, C., Awford, A., Procter, N., Chong, C. -R., Liu, S., . . . Horowitz, J. (2018). Atrial Fibrillation Ablation May Suppress Systemic Inflammatory Activation by Inhibiting Thioredoxin Interacting Protein Expression. In Circulation. 2016 Vol. 134 (pp. 8 pages). New Orleans, LA: LIPPINCOTT WILLIAMS & WILKINS. 2018 Nguyen, T. H., Stansborough, J., Ong, G. J., Surikow, S. H., & Horowitz, J. D. (2018). Does Concomitant Malignancy Exacerbate the Course of Takotsubo Syndrome?. In CIRCULATION Vol. 138 (pp. 2 pages). LIPPINCOTT WILLIAMS & WILKINS. 2018 Aulin, J., Hijazi, Z., Lindback, J., Alexander, J. H., Gersh, B., Granger, C. B., . . . Wallentin, L. (2018). Elevated biomarkers are associated with increased risk of death and heart failure hospitalization in patients with atrial fibrillation: insights from the ARISTOTLE trial. In EUROPEAN HEART JOURNAL Vol. 39 (pp. 196). Munich, GERMANY: OXFORD UNIV PRESS. 2018 Imam, H., Nguyen, T. H., Tu, S., Tonnu, O., Chirkov, Y., & Horowitz, J. (2018). Pathogenesis of coronary artery spasm: a critical role for impaired platelet nitric oxide signaling. In EUROPEAN HEART JOURNAL Vol. 39 (pp. 336). Munich, GERMANY: OXFORD UNIV PRESS. 2017 Nguyen, T. H., Stansborough, J., Ong, G. J., Surikow, S., Frenneaux, M. P., & Horowitz, J. D. (2017). Implications of "Secondary" Takotsubo Syndrome on Short and Longterm Event Rates. In CIRCULATION Vol. 136 (pp. 2 pages). Anaheim, CA: LIPPINCOTT WILLIAMS & WILKINS. 2017 Chong, C. -R., Imam, H., Sallustio, B., Chirkov, Y. Y., & Horowitz, J. D. (2017). Perhexiline enhances cGMP- and cAMP-signaling in diabetics independent of insulin sensitization and ACE inhibition. In EUROPEAN HEART JOURNAL Vol. 38 (pp. 1143). OXFORD UNIV PRESS. 2017 Aulin, J., Hijazi, Z., Andersson, U., Alexander, J. H., Gersh, B., Granger, C. B., . . . Wallentin, L. (2017). Serial IL-6 levels and risk of death in anticoagulated patients with atrial fibrillation: Insights from the ARISTOTLE trial. In EUROPEAN HEART JOURNAL Vol. 38 (pp. 780). OXFORD UNIV PRESS. 2017 Imam, H., Nguyen, T. H., Tee, S. -L., Tonnu, O., Chirkov, Y. Y., & Horowitz, J. D. (2017). Impaired cGMP and cAMP signaling in patients with coronary vasospasm: changes during acute crises. In EUROPEAN HEART JOURNAL Vol. 38 (pp. 794). OXFORD UNIV PRESS. 2016 Qin, C. X., Anthonisz, J., Kahlberg, N., Leo, C. H., Jap, E., Parry, L. J., . . . Ritchie, R. (2016). Approaches for Overcoming Diabetes-Induced Cardiovascular Nitric Oxide Resistance. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 100 (pp. S150-S151). ELSEVIER SCIENCE INC.
2016 Neil, C. J. A., Ahearn, T., Scully, C., Jagpal, B., Rudd, A., Horowitz, J. D., . . . Dawson, D. (2016). Evidence of diffuse myocardial fibrosis late after tako-tsubo cardiomyopathy: a case-control study using T1-mapping. In EUROPEAN HEART JOURNAL Vol. 37 (pp. 1234). Rome, ITALY: OXFORD UNIV PRESS. 2016 Liu, S., Assadi-Khansari, B., Ajaero, C., Chua, S. J., Horowitz, J. D., Ngo, D. T., & Sverdlov, A. L. (2016). Follistatin-Like 3 is Elevated In Acute Heart Failure Patients. In CIRCULATION Vol. 134 (pp. 7 pages). Pentagon City, VA: LIPPINCOTT WILLIAMS & WILKINS. 2015 Schwarz, K., Srinivasan, J., Bruce, M., Neil, C. J., Scally, C., Horowitz, J. D., . . . Dawson, D. K. (2015). Apical variant Tako-tsubo is associated with persistent myocardial strain dysfunction. In EUROPEAN HEART JOURNAL Vol. 36 (pp. 943-944). London, ENGLAND: OXFORD UNIV PRESS. 2015 Chong, C. -R., Stansbourough, J., Raman, B., Nguyen, T. H., Neil, C. J., & Horowitz, J. D. (2015). Determinants of shock and mortality in Takotsubo cardiomyopathy: a cohort study. In EUROPEAN HEART JOURNAL Vol. 36 (pp. 1177-1178). London, ENGLAND: OXFORD UNIV PRESS. 2013 Siddiqi, N., Bruce, M., Neil, C. J., MacLennan, G., Cotton, S., Papadopoulou, S. A., . . . Frenneaux, M. P. (2013). Nitrites in Acute Myocardial Infarction. In CIRCULATION Vol. 128 (pp. 2705). LIPPINCOTT WILLIAMS & WILKINS.
WoS12013 Goto, S., Zhu, J., Lisheng, L., Oh, B. H., Wojdyla, D., Hanna, M., . . . Alexander, J. H. (2013). Efficacy and safety of apixaban compared with warfarin for stroke prevention in atrial fibrillation in East Asia. In EUROPEAN HEART JOURNAL Vol. 34 (pp. 1039). Amsterdam, NETHERLANDS: OXFORD UNIV PRESS.
WoS52012 Siegbahn, A., Christersson, C., Schollin, M., Alexander, J. H., Horowitz, J., Hylek, E. M., . . . Wallentin, L. (2012). Increased levels of D-dimer identify patients with atrial fibrillation at high risk for bleeding an ARISTOTLE substudy. In EUROPEAN HEART JOURNAL Vol. 33 (pp. 51). Munchen, GERMANY: OXFORD UNIV PRESS.
WoS52012 Christersson, C., Schollin, M., Alexander, J. H., Bersh, B. J., Horowitz, J., Hylek, E. M., . . . Siegbahn, A. (2012). Increased levels of D-dimer in atrial fibrillation identify patients with higher risk of thromboembolic events and death. In EUROPEAN HEART JOURNAL Vol. 33 (pp. 969). Munchen, GERMANY: OXFORD UNIV PRESS. 2012 Wallentin, L. C., Christersson, C., Siegbahn, A., Schollin, M., Alexander, J. H., Hanna, M., . . . Granger, C. B. (2012). NT-proBNP for risk stratification in atrial fibrillation during treatment with apixaban or warfarin. In EUROPEAN HEART JOURNAL Vol. 33 (pp. 51). Munchen, GERMANY: OXFORD UNIV PRESS.
WoS22012 Ritchie, R. H., Irvine, J. C., Ganthavee, V., Love, J. E., Alexander, A. E., Horowitz, J. D., . . . Kemp-Harper, B. K. (2012). The Soluble Guanylyl Cyclase (sGC) Activator BAY 58-2667 Selectively Limits Cardiomyocyte Hypertrophy - A Potential Therapeutic Advantage for Managing Left Ventricular Hypertrophy (LVH). In CIRCULATION Vol. 126 (pp. 1 page). LIPPINCOTT WILLIAMS & WILKINS. 2010 Das, D., Horowitz, J. D., & Kennedy, J. A. (2010). Nitric oxide inhibits tgf-beta1 induced collagen synthesis in porcine and human aortic valve cells. In EUROPEAN HEART JOURNAL Vol. 31 (pp. 963). Stockholm, SWEDEN: OXFORD UNIV PRESS. 2010 Sverdlov, A. L., Ngo, D. T., Nightingale, A. K., Rajendran, S., Ritchie, R. H., Marwick, T. H., . . . Horowitz, J. D. (2010). Relationship between LV mass and diastolic function is independent of NO generation. In EUROPEAN HEART JOURNAL Vol. 31 (pp. 121). Stockholm, SWEDEN: OXFORD UNIV PRESS. 2010 Chan, W. P., Ngo, D. T., Rajendran, S., Heresztyn, T., Amarasekera, A., Sverdlov, A. L., . . . Horowitz, J. D. (2010). Implications of insulin sensitivity on inflammatory activation and atherogenic risk in normal and PCOS females. In EUROPEAN HEART JOURNAL Vol. 31 (pp. 544). Stockholm, SWEDEN: OXFORD UNIV PRESS. 2010 Kucia, A., Neil, C., Nguyen, T., Beltrame, J., Arstall, M., & Horowitz, J. (2010). Evolution of ECG changes in Tako Tsubo Cardiomyopathy: Arrhythmias first, QT Prolongation later?. In Proceedings of the Cardiac Society of Australia and New Zealand and the International Society for Heart Research Australasian Section Annual Scientific meeting Vol. 19 (pp. 225). Elsevier BV.
2010 Neil, C., Kucia, A., Nguyen, H., Sverdlov, A., Chan, A., Dautov, R., . . . Horowitz, J. (2010). Relationship between precipitant stressor and timing of clinical diagnosis in Tako-Tsubo Cardiomyopathy. In Proceedings of Cardiac Society of Australia and New Zealand and the International Society for Heart Research Australasian Section Annual Scientific Meeting (pp. 225). ISHR. 2007 Philpott, A. C., Sage, P. R., Stafford, I., Murphy, G., de la Lande, I., Stuklis, R., . . . Horowitz, J. D. (2007). Dissociation of aldehyde dehydrogenase activity from nitrate effect, bioconversion, and tolerance in humans. In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol. 49 (pp. 420A). New Orleans, LA: ELSEVIER SCIENCE INC. 2007 Ngo, D. T., Stafford, I., Wuttke, R. D., Weedon, H., Smith, M. D., Kelly, D. J., . . . Horowitz, J. D. (2007). Ramipril retards development of aortic valve stenosis in a rabbit model: Role of thioredoxin interacting protein. In CIRCULATION Vol. 116 (pp. 679-680). Orlando, FL: LIPPINCOTT WILLIAMS & WILKINS. 2006 Rosenkranz, A. C., Kennedy, J. A., Murphy, G., Hua, X., Mishra, K., & Horowitz, J. D. (2006). Pivotal role of Rho kinase activation rather than oxidative stress in calcification of aortic valve interstitial cells. In EUROPEAN HEART JOURNAL Vol. 27 (pp. 574). Barcelona, SPAIN: OXFORD UNIV PRESS. 2006 Ngo, D. T., Wuttke, R. D., Weedon, H., Nightingale, A. K., Sverdlov, A. L., Kennedy, J. A., & Horowitz, J. D. (2006). Vitamin D2 supplementation induces aortic stenosis in rabbits. In EUROPEAN HEART JOURNAL Vol. 27 (pp. 574). Barcelona, SPAIN: OXFORD UNIV PRESS. 2006 Ngo, D. T., Wuttke, R. D., Stafford, I., Rosenkranz, A. R., Sverdlov, A. L., Chirkov, Y. Y., . . . Horowitz, J. D. (2006). Effects of vitamin D2 supplementation on aortic valvular and vascular endothelial functions in a rabbit model of aortic stenosis. In EUROPEAN HEART JOURNAL Vol. 27 (pp. 127). Barcelona, SPAIN: OXFORD UNIV PRESS. 2006 Nightingale, A. K., Rajendran, S., Sverdlov, A., Mishra, K., Ngo, D., Heresztyn, T., & Horowitz, J. D. (2006). Aortic sclerosis precedes development of systemic endothelial dysfunction. In EUROPEAN HEART JOURNAL Vol. 27 (pp. 743). Barcelona, SPAIN: OXFORD UNIV PRESS. 2006 Chirkov, Y. Y., Rajendran, S., Sverdlov, A. L., & Horowitz, J. D. (2006). Potentiation of platelet responsiveness to nitric oxide by angiotensin-(1-7) is mediated by its specific receptor and is associated with the suppression of superoxide release. In EUROPEAN HEART JOURNAL Vol. 27 (pp. 128). Barcelona, SPAIN: OXFORD UNIV PRESS. 2006 Inglis, S. C., Horowitz, J. D., & Stewart, S. (2006). Ten-year follow-up of a nurse-led, multidisciplinary, home-based intervention in typically old and fragile patients: Cost-benefits and outcomes. In CIRCULATION Vol. 114 (pp. 573). Chicago, IL: LIPPINCOTT WILLIAMS & WILKINS. 2005 Rajendran, S., Willoughby, S. R., Kelly, E. A., Heresztyn, T., Norman, R. J., & Horowitz, J. D. (2005). Polycystic ovarian syndrome is associated with severe platelet and endothelial dysfunction independent of metabolic syndrome. In CIRCULATION Vol. 112 (pp. U42). Dallas, TX: LIPPINCOTT WILLIAMS & WILKINS. 2005 Rajendran, S., Willoughby, S. R., Kelly, E. A., Heresztyn, T., Norman, R. J., & Horowitz, J. D. (2005). Polycystic ovarian syndrome is associated with severe platelet and endothelial dysfunction independent of metabolic syndrome. In CIRCULATION Vol. 112 (pp. U435). Dallas, TX: LIPPINCOTT WILLIAMS & WILKINS.
WoS12005 Ngo, D. T., Heresztyn, T., Mishra, K., Marwick, T., & Horowitz, J. (2005). Aortic stenosis is associated with elevated plasma levels of asymmetric dimethylarginine (ADMA). In CIRCULATION Vol. 112 (pp. U753). Dallas, TX: LIPPINCOTT WILLIAMS & WILKINS. 2005 Willoughby, S. R., Stewart, S., Holmes, A. S., Chirkov, Y. Y., & Horowitz, J. D. (2005). Impaired platelet nitric oxide responsiveness is an independent predictor of cardiovascular related readmission, cardiovascular death and all cause mortality in high risk patients,with acute coronary syndromes. In CIRCULATION Vol. 112 (pp. U127). Dallas, TX: LIPPINCOTT WILLIAMS & WILKINS. 2004 Campbell, D. J., Zeitz, C. J., Esler, M. D., & Horowitz, J. D. (2004). ACE2 does not play a major role in angiotensin peptide metabolism in the human coronary circulation. In JOURNAL OF HYPERTENSION Vol. 22 (pp. S152). Paris, FRANCE: LIPPINCOTT WILLIAMS & WILKINS.
2004 Lee, L., Taylor, R., Campbell, R., Williams, L., Gunaruwan, P., Horowitz, J., . . . Frenneaux, M. (2004). Metabolic modulation with perhexiline improves myocardial function in ischemic heart failure. In CIRCULATION Vol. 110 (pp. 679). New Orleans, LA: LIPPINCOTT WILLIAMS & WILKINS. 2004 Lee, L., Scheurmann-Freestone, M., Campbell, R., Field, R., Gunaruwan, P., Horowitz, J., . . . Frenneaux, M. (2004). Augmentation of glucose metabolism with perhexiline in non-ischaemic heart failure. In HEART Vol. 90 (pp. A2). Manchester, ENGLAND: B M J PUBLISHING GROUP. 2004 Chirkov, Y. Y., Rajendran, S., & Horowitz, J. D. (2004). Angiotensin-(1-7) potentiates the antiaggregatory effects of nitric oxide. In CIRCULATION Vol. 110 (pp. 216). New Orleans, LA: LIPPINCOTT WILLIAMS & WILKINS. 2004 Chirkov, Y. Y., Rajendran, S., & Horowitz, J. D. (2004). Angiotensin-(1-7) improves platelet responsiveness to anti-aggregatory effects of nitric oxide. In EUROPEAN HEART JOURNAL Vol. 25 (pp. 90). Munich, GERMANY: W B SAUNDERS CO LTD. 2003 Chirkov, Y. Y., Holmes, A. S., Chandy, S., & Horowitz, J. D. (2003). Aortic stenosis is associated with valvular endothelial dysfunction. In CIRCULATION Vol. 108 (pp. 431). ORLANDO, FLORIDA: LIPPINCOTT WILLIAMS & WILKINS. 2003 Stewart, S., Inglis, S., & Horowitz, J. D. (2003). Long-term cost impact of a nurse-led, home-based, multidisciplinary intervention for patients with chronic heart failure. In CIRCULATION Vol. 108 (pp. 504). ORLANDO, FLORIDA: LIPPINCOTT WILLIAMS & WILKINS. 2003 Willoughby, S. R., Stewart, S., Chirkov, Y. Y., Holmes, A. S., & Horowitz, J. D. (2003). A novel prognostic marker in acute coronary syndromes: Platelet nitric oxide responsiveness. In CIRCULATION Vol. 108 (pp. 681). ORLANDO, FLORIDA: LIPPINCOTT WILLIAMS & WILKINS. 2003 Inglis, S., Dawson, A. P., Wilkinson, D., Horowitz, J. D., & Stewart, S. (2003). A new solution to an old problem? Effects of a nurse-led home-based intervention in chronic atrial fibrillation. In EUROPEAN HEART JOURNAL Vol. 24 (pp. 484). VIENNA, AUSTRIA: W B SAUNDERS CO LTD.
2003 Worthley, M. I., Holmes, A. S., Willoughby, S. R., Kucia, A. M., Heresztyn, T., Stewart, S., . . . Horowitz, J. D. (2003). The deleterious effects of hyperglycemia on platelet function in diabetic patients with acute coronary syndrome: Mediation by superoxide production, resolution with intensive insulin administration. In CIRCULATION Vol. 108 (pp. X). ORLANDO, FLORIDA: LIPPINCOTT WILLIAMS & WILKINS. 2003 Worthley, M. I., Holmes, A. S., Willoughby, S. R., Kucia, A. M., Heresztyn, T., Chirkov, Y. Y., . . . Horowitz, J. D. (2003). The deleterious effects of hyperglycemia on platelet function in diabetic patients with acute coronary syndrome: Mediation by superoxide production, resolution with intensive insulin administration. In CIRCULATION Vol. 108 (pp. 311). ORLANDO, FLORIDA: LIPPINCOTT WILLIAMS & WILKINS.
WoS12003 Willoughby, S. R., Stewart, S., Chirkov, Y. Y., Kennedy, J. A., Holmes, A. S., & Horowitz, J. D. (2003). Platelet nitric oxide responsiveness: a novel prognostic indicator for acute coronary syndromes. In EUROPEAN HEART JOURNAL Vol. 24 (pp. 293). VIENNA, AUSTRIA: W B SAUNDERS CO LTD.
2003 Kucia, A., Zeitz, C., & Horowitz, J. (2003). Time course of incidence of ventricular fibrillation peri-acute ST-segment myocardial infarction: Impact of successful reperfusion.. In CIRCULATION Vol. 108 (pp. A1039). ORLANDO, FLORIDA: LIPPINCOTT WILLIAMS & WILKINS. 2003 Worthley, M. I., Willoughby, S. R., Kucia, A. M., Holmes, A. S., Chirkov, Y. Y., Zeitz, C. J., & Horowitz, J. D. (2003). Determinants of platelet nitric oxide response and superoxide levels in diabetic patients with acute coronary syndrome. In EUROPEAN HEART JOURNAL Vol. 24 (pp. 128). VIENNA, AUSTRIA: W B SAUNDERS CO LTD.
2002 Worthley, M., Holmes, A. S., Chirkov, Y. Y., Zeitz, C. J., & Horowitz, J. D. (2002). Acute resolution of hyperglycemia normalizes platelet responsiveness to nitric oxide in diabetics with acute coronary syndromes. In EUROPEAN HEART JOURNAL Vol. 23 (pp. 495). BERLIN, GERMANY: W B SAUNDERS CO LTD. 2002 Sage, P. R., de la Lande, I. S., Stafford, I., Siebert, T., Stubberfield, J., & Horowitz, J. D. (2002). Nitrate tolerance in human vessels: The role of the endothelium and effect of anti-oxidant therapy. In CIRCULATION Vol. 106 (pp. 412). CHICAGO, ILLINOIS: LIPPINCOTT WILLIAMS & WILKINS. 2002 Stewart, S., Berry, C., Horowitz, J. D., & McMurray, J. J. V. (2002). Prevalence, characteristics and prognostic signficance of anaemia in heart failure. In EUROPEAN HEART JOURNAL Vol. 23 (pp. 272). BERLIN, GERMANY: W B SAUNDERS CO LTD. 2002 Stewart, S., & Horowitz, J. D. (2002). Prolonged survival and fewer readmissions: the long-term effects of a home-based intervention in chronic heart failure. In EUROPEAN HEART JOURNAL Vol. 23 (pp. 272). BERLIN, GERMANY: W B SAUNDERS CO LTD. 2002 Stewart, S., & Horowitz, J. D. (2002). Reduced morbidity, prolonged survival and reduced health care costs: The long-term effects of post-discharge, home-based intervention in chronic heart failure. In CIRCULATION Vol. 106 (pp. 370). CHICAGO, ILLINOIS: LIPPINCOTT WILLIAMS & WILKINS. 2001 Worthley, M. I., Holmes, A. S., Chirkov, Y. Y., Zeitz, C. J., & Horowitz, J. D. (2001). Glycemic control and platelet function in diabetic patients with threatened myocardial infarction.. In CIRCULATION Vol. 104 (pp. 378). LIPPINCOTT WILLIAMS & WILKINS. 2001 Kucia, A., Horowitz, J. D., & South, K. (2001). Frequency and clinical significance of T-wave fluctuation immediately following percutaneous transluminal coronary angioplasty. In EUROPEAN HEART JOURNAL Vol. 22 (pp. 215). W B SAUNDERS CO LTD. 2001 Kennedy, J. A., Murphy, G. M., Zhang, Y., & Horowitz, J. D. (2001). The antianginal agent, perhexiline, inhibits the activation of NADPH oxidase in human neutrophils. In EUROPEAN HEART JOURNAL Vol. 22 (pp. 292). W B SAUNDERS CO LTD. 2000 Anderson, R. A., Gapper, P., Khan, N., Ellis, G. R., Chirkov, Y. Y., Horowitz, J. D., . . . Frenneaux, M. P. (2000). Fasting and postprandial platelet nitrate responsiveness in type 2 diabetes.. In CIRCULATION Vol. 102 (pp. 334). LIPPINCOTT WILLIAMS & WILKINS. 2000 Anderson, R. A., Ellis, G. R., Blackman, D. J., Chirkov, Y. Y., James, P. E., Jackson, S. K., . . . Frenneaux, M. P. (2000). Primary platelet nitric oxide resistance and oxidative stress in patients with chronic heart failure. In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol. 35 (pp. 222A). ELSEVIER SCIENCE INC. 2000 Kucia, A., Briggs, J. M., & Horowitz, J. D. (2000). Incidence, duration and outcome of recurrent ST-segment elevation in the first 24 hours post commencement of thrombolytic therapy for acute myocardial infarction. In EUROPEAN HEART JOURNAL Vol. 21 (pp. 32). W B SAUNDERS CO LTD. 2000 Sage, P. R., De La Lande, I. S., Stafford, I., Stubberfield, J., & Horowitz, J. D. (2000). De novo impairment of vascular responsiveness to nitroglycerin in patients with multiple coronary risk factors.. In CIRCULATION Vol. 102 (pp. 758). LIPPINCOTT WILLIAMS & WILKINS. 2000 Warner, A., Saint, K., Arstall, M., & Horowitz, J. (2000). Hypoxia-induced iNOS expression in rats is age dependent. In EUROPEAN HEART JOURNAL Vol. 21 (pp. 47). W B SAUNDERS CO LTD. 1999 Sage, P. R., de la Lande, I. S., Irene, S., Bennett, C. L., Stubberfield, J., & Horowitz, J. D. (1999). Nitrate tolerance to low dose intravenous nitroglycerin is associated with reduced bioconversion. In CIRCULATION Vol. 100 (pp. 186). LIPPINCOTT WILLIAMS & WILKINS. 1999 Unger, S. A., Robinson, M. A., Wuttke, R. D., & Horowitz, J. D. (1999). Perhexiline improves symptomatic status and survival in elderly patients with critical aortic stenosis. In CIRCULATION Vol. 100 (pp. 18). LIPPINCOTT WILLIAMS & WILKINS. 1999 Horowitz, J. D. (1999). Part II: The ATLAS study: Low-dose versus high-dose lisinopril in heart failure. In International Journal of Clinical Practice, Supplement (pp. 15-16). VIENNA, AUSTRIA: MEDICOM INTERNATIONAL.
Scopus2 WoS31998 Stewart, S., Vandenbroek, A. J., Pearson, S., & Horowitz, J. D. (1998). Prolonged benefits of a home-based intervention on unplanned readmissions and mortality among chronic congestive heart failure patients. In CIRCULATION Vol. 98 (pp. 483). LIPPINCOTT WILLIAMS & WILKINS. 1998 Zhang, Y., Oliver, J. R., & Horowitz, J. D. (1998). Control of endothelin release within the heart: Vasomotor and inotropic implications during ischemia/reperfusion. In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol. 31 (pp. 134A). ELSEVIER SCIENCE INC.
1998 Zeitz, C. J., Campbell, D. J., Pelle, M. A., Ninio, D. M., & Horowitz, J. D. (1998). Perindoprilat improves coronary vasodilator reserve during induction of myocardial ischemia.. In CIRCULATION Vol. 98 (pp. 487-488). LIPPINCOTT WILLIAMS & WILKINS.
WoS21996 Chirkov, Y. Y., Willoughby, S. R., Chirkova, L. P., & Horowitz, J. D. (1996). Perhexiline and amiodarone inhibit platelet aggregation in patients with angina pectoris.. In CIRCULATION Vol. 94 (pp. 1338). AMER HEART ASSOC. 1995 CHIRKOV, Y. Y., CHIRKOVA, L. P., YANG, J. F., & HOROWITZ, J. D. (1995). TOLERANCE TO NITROGLYCERIN AT THE LEVEL OF PLATELET AGGREGABILITY IN PATIENTS WITH STABLE ANGINA-PECTORIS. In CIRCULATION Vol. 92 (pp. 1433). AMER HEART ASSOC. 1993 CHIRKOV, Y. Y., YANG, J. F., NAUJALIS, J. I., SAGE, R. E., & HOROWITZ, J. D. (1993). IMPAIRED PLATELET RESPONSES TO CGMP-ELEVATING AND ANTI-AGGREGATING ACTION OF NITROGLYCERIN AND SODIUM-NITROPRUSSIDE IN PATIENTS WITH STABLE ANGINA. In CIRCULATION Vol. 88 (pp. 90). AMER HEART ASSOC. 1993 BETTS, W. H., ZHANG, Y., ROKICINSKI, M., & HOROWITZ, J. D. (1993). N-ACETYLCYSTEINE AND CAPTOPRIL INHIBIT BUT S-NITROSO-N-ACETYLCYSTEINE STIMULATES HUMAN NEUTROPHIL FREE-RADICAL PRODUCTION. In CIRCULATION Vol. 88 (pp. 90). AMER HEART ASSOC.
WoS51993 ZHANG, C. L., STAFFORD, I., ZHANG, Y., & HOROWITZ, J. D. (1993). RELEASE OF 3'5' CYCLIC GUANOSINE-MONOPHOSPHATE ACROSS THE FEMORAL VASCULAR BED IN MAN DURING ACUTE AND CHRONIC NITRATE THERAPY. In CIRCULATION Vol. 88 (pp. 91). AMER HEART ASSOC. 1992 CHIRKOV, Y. Y., YANG, J. F., NAUJALIS, J. I., SAGE, R. E., & HOROWITZ, J. D. (1992). DIFFERENCES IN EFFECTS OF NITROGLYCERIN AND SODIUM-NITROPRUSSIDE ON HUMAN PLATELETS INVITRO - INTRAPLATELET CGMP CONTENT AND REVERSAL OF AGGREGATION. In CIRCULATION Vol. 86 (pp. 488). AMER HEART ASSOC. -
Conference Items
Year Citation 2020 Qin, C. X., Anthonisz, J., Huei, L. C., Kahlberg, N., Jap, E., Oodman, O. L. W., . . . Ritchie, R. H. (2020). Diabetes-induced myocardial NO<SUP>•</SUP> resistance, is circumvented by the nitric oxide (NO) redox sibling, nitroxyl, HNO. Poster session presented at the meeting of JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. Beijing, PEOPLES R CHINA: ELSEVIER SCI LTD.
2019 Liu, S., Nguyen, T. H., Imam, H., Heresztyn, T., Stafford, I., Chirkov, Y. Y., & Horowitz, J. D. (2019). Coronary artery spasm: a consequence of impaired nitric oxide/hydrogen sulphide signalling?. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Paris, FRANCE: OXFORD UNIV PRESS. 2019 Nguyen, T. H., Liu, S., Imam, H., Heresztyn, T., Stafford, I., Chirkov, Y. Y., & Horowitz, J. D. (2019). Pathogenesis of symptomatic crises in patients with coronary artery spasm: evidence for acute damage to vascular glycocalyx and to circulating platelets. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Paris, FRANCE: OXFORD UNIV PRESS. 2019 Ong, G. J., Stansborough, J., Nguyen, T. H., & Horowitz, J. D. (2019). Iatrogenic takotsubo syndrome: incidence and impact. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Paris, FRANCE: OXFORD UNIV PRESS. 2019 Liu, S., & Horowitz, J. (2019). N-acetylcysteine reverses peroxynitrite and hydrogen peroxide-induced apoptosis of human myocardial cells. Poster session presented at the meeting of Abstracts of the 68th Annual Scientific Session and Expo of the American College of Cardiology (ACC.19), as published in Journal of the American College Of Cardiology. New Orleans, LA: Elsevier.
2018 Sarcon, A., Templin, C., Ghadri, J., Cammann, V., Ding, K., Kato, K., & Gili, S. (2018). TAKOTSUBO SYNDROME CLASSIFIED: TRIGGERS DETERMINE OUTCOME: RESULTS FROM THE INTERTAK REGISTRY. Poster session presented at the meeting of JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. Orlando, FL: ELSEVIER SCIENCE INC.
WoS352017 Procter, N. E. K., Pasupathy, S., Stafford, I., Heresztyn, T., Liu, S., Selvanayagam, J., . . . Horowitz, J. D. (2017). Glycocalyx shedding in acute myocardial infarction: interactions with reperfusion and n-acetylcysteine therapy. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. OXFORD UNIV PRESS. 2017 Imam, H., Nguyen, T. H., Chirkov, Y., De Caterina, R., & Horowitz, J. (2017). Adenylate cyclase signaling is an important post-receptor determinant of response to all P2Y12 receptor antagonists. Poster session presented at the meeting of European Heart Journal. Barcelona: Oxford University Press.
2017 Nguyen, T. H. (2017). Hypotension at admission and extent of release of NT-proBNP and catecholamines are associated with increased medium-term mortality rate in Takotsubo cardiomyopathy.. Poster session presented at the meeting of European Heart Journal. Bardelona: Oxford University Press. 2016 Procter, N. E. K., Ball, J., Ngo, D. T. M., Chirkov, Y. Y., Stewart, S., & Horowitz, J. D. (2016). Platelet hypo-responsiveness to nitric oxide in new onset atrial fibrillation has a physiological, as opposed to pharmacological, basis. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Rome, ITALY: OXFORD UNIV PRESS. 2016 Assadi-Khansari, B., Chua, S. J., Chapman, M., Ali, O., Nguyen, H., Horowitz, J. D., . . . Ngo, D. T. M. (2016). Follistatin-like 3 predicts aortic root enlargement in patients with bicuspid aortic valve. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Rome, ITALY: OXFORD UNIV PRESS. 2016 Chua, S. J., Ajaero, C., Assadi-Khansari, B., McGavigan, A., Horowitz, J. D., Sverdlov, A. L., & Ngo, D. T. M. (2016). Galectin 3 is markedly elevated in severe heart failure and predicts improvement in LV volumes post cardiac resynchronisation therapy. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Rome, ITALY: OXFORD UNIV PRESS. 2016 Nguyen, T. H., Liu, S., Ong, G., Stafford, I., Frenneaux, M., & Horowitz, J. D. (2016). Glycocalyx shedding is markedly increased during the acute phase of Takotsubo cardiomyopathy. Poster session presented at the meeting of Abstracts of the American Heart Association Scientific Sessions and Resuscitation Science Symposium 2016, as published in Circulation. New Orleans, LA: American Heart Association. 2015 Liu, S., Ngo, D. T., Chong, C. R., Chan, W. P., Horowitz, J. D., & Chirkov, Y. Y. (2015). Tachyphylaxis to the anti-inflammatory effects of BNP in acute heart failure:-potential response to therapy. Poster session presented at the meeting of EUROPEAN JOURNAL OF HEART FAILURE. WILEY-BLACKWELL. 2014 Asberg, S., Hijazi, Z., Siegbahn, A., Andersson, U., Granger, C. B., Hanna, M., . . . Wallentin, L. (2014). Galectin-3 is associated with worse clinical outcome in patients with atrial fibrillation: A substudy from the ARISTOTLE trial. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Barcelona, SPAIN: OXFORD UNIV PRESS.
WoS22014 Aulin, J., Hijazi, Z., Andersson, U., Gersh, B. J., Hanna, M., Horowitz, J. D., . . . Wallentin, L. (2014). Interleukin-6 and C-reactive protein and risk for cardiovascular events and death in anticoagulated patients with atrial fibrillation. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Barcelona, SPAIN: OXFORD UNIV PRESS. 2014 Nooney, V. B., Chirkov, Y. Y., De Caterina, R., & Horowitz, J. D. (2014). Ticagrelor potentiates the anti-aggregatory effects of adenosine via A2 receptor stimulation. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Barcelona, SPAIN: OXFORD UNIV PRESS. 2014 Procter, N. E. K., Ball, J., Ngo, D. T. M., Chirkov, Y. Y., Isenberg, J. S., Hylek, E. M., . . . Horowitz, J. D. (2014). Gender/tachycardia interactions in atrial fibrillation: impact upon platelet aggregation and nitric oxide signalling. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Barcelona, SPAIN: OXFORD UNIV PRESS. 2014 Liu, S., Ngo, D., Chong, C. -R., Chirkov, Y., Stewart, S., & Horowitz, J. (2014). Mechanisms of BNP interactions with neutrophil superoxide release: attenuation in acute and chronic heart failure. Poster session presented at the meeting of Global Heart. 2013 Amarasekera, A. T., Sverdlov, A. L., Roberts, M. S., Horowitz, J. D., & Ngo, D. T. (2013). Elevated parathyroid hormone predicts high asymmetric dimethylarginine (ADMA) concentrations; independent of vitamin D status. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Amsterdam, NETHERLANDS: OXFORD UNIV PRESS.
WoS12013 Raman, B., Singh, K., Neil, C., Nguyen, T. H., Stansborough, J., Zietz, C., & Horowitz, J. D. (2013). Not such a rarity: takotsubo cardiomyopathy as a mimic of ST elevation myocardial infarction. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Amsterdam, NETHERLANDS: OXFORD UNIV PRESS. 2013 Horowitz, J., Nguyen, T., Neil, C., Singh, K., Chong, C., Licari, J., & Raman, B. (2013). Stress cardiomyopathy: new clinical and pathogenetic insights. Poster session presented at the meeting of Abstracts of the 10th International Congress on Coronary Artery Disease (ICCAD), as published in Cardiology. Florence, Italy: Karger.
2013 Arif, S., Feelisch, M., Horowitz, J. D., Frenneaux, M. P., & Madhani, M. (2013). Aldehyde dehydrogenase plays an important role in nitrite-mediated vasorelaxation during hypoxic conditions. Poster session presented at the meeting of NITRIC OXIDE-BIOLOGY AND CHEMISTRY. Pittsburgh, PA: ACADEMIC PRESS INC ELSEVIER SCIENCE.
WoS12013 Hijazi, Z., Siegbahn, A., Andersson, U., Granger, C. B., Alexander, J. H., Atar, D., . . . Wallentin, L. (2013). Combining High Sensitivity Troponin I and T Measurements Improves Prediction of Long-Term Clinical Outcomes in Patients With Atrial Fibrillation - An Aristotle Substudy. Poster session presented at the meeting of CIRCULATION. Dallas, TX: LIPPINCOTT WILLIAMS & WILKINS. 2013 Horowitz, J. D., De Caterina, R., Heresztyn, T., Andersson, U., Lopes, R., Hylek, E., . . . Wallentin, L. (2013). ADMA and SDMA predict outcomes in patients with chronic atrial fibrillation: an ARISTOTLE substudy. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Amsterdam, NETHERLANDS: OXFORD UNIV PRESS.
WoS42013 Liu, S., Ngo, D., Chirkov, Y., Stewart, S., & Horowitz, J. (2013). Impaired B-type natriuretic peptide effets on neutrophil burst in heart failure patients. Poster session presented at the meeting of Abstracts of the American Heart Association 2013 Scientific Sessions and Resuscitation Science Symposium, as publshed in Circulation. Dallas, TX: American Heart Association. 2013 Licari, G., Singh, K., Chong, C., Thanh, N., Chapman, M., Stafford, I., . . . Horowitz, J. (2013). Increased myocardial expression of thioredoxin-interacting protein, and evidence of nitrosative stress in a rat model of Tako-Tsubo Cardiomyopathy. Poster session presented at the meeting of Abstracts of the American Heart Association 2013 Scientific Sessions and Resuscitation Science Symposium, as publshed in Circulation. Dallas, TX: Amercian Heart Association. 2013 Amarasekera, A., Black, M., Jansen, F., Dymmott, G., Roberts, M., Chirkov, Y., . . . Ngo, D. (2013). Vitamin D supplementation in healthy adults lowers plasma Thrombospondin-1 levels: a novel vitamin D target?. Poster session presented at the meeting of Abstracts of the American Heart Association 2013 Scientific Sessions and Resuscitation Science Symposium, as publshed in Circulation. Dallas, TX: American Heart Association. 2013 Chong, C., Liu, S., Licari, G., Chirkov, Y., Ngo, D., & Horowitz, J. (2013). Reversal of acute hyperglycemia restores tissue responsiveness to nitric oxide and improves endothelial progenitor cell function without downregulating platelet thioredoxin interacting protein. Poster session presented at the meeting of Abstracts of the American Heart Association 2013 Scientific Sessions and Resuscitation Science Symposium, as publshed in Circulation. Dallas, TX: American Heart Association. 2013 Nguyen, T. H., Neil, C., Singh, K., Heresztyn, T., Chirkov, Y., & Horowitz, J. (2013). Determinants of prolonged impairment of global longitudinal strain post Takotsubo cardiomyopathy. Poster session presented at the meeting of Abstracts of the European Society of Cardiology Congress 2013 (ESC 2013), as published in European Heart Journal. Amsterdam, NETHERLANDS: Oxford University Press.
2013 Nooney, V. B., Hurst, N., Chirkov, Y. Y., & Horowitz, J. H. (2013). Acute effects of clopidogrel are predicted by integrity of prostacyclin signalling. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Amsterdam, NETHERLANDS: OXFORD UNIV PRESS. 2012 Nguyen, T. H., Neil, A., Sverdlov, A., Ngo, D., Chan, W., Chirkov, Y., . . . Horowitz, J. (2012). Paradoxical preservation of NO signalling in Takotsubo cardiomyopathy. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Munchen, GERMANY: OXFORD UNIV PRESS. 2012 Neill, C. J., Nguyen, T. H., Stansborough, J., Rong, C. -R., Singh, K., Kucia, A., & Horowitz, J. D. (2012). Utility of a TTC Score to facilitate differentiation of Tako-Tsubo Cardiomyopathy from Ischemic ACS. Poster session presented at the meeting of CIRCULATION. LIPPINCOTT WILLIAMS & WILKINS. 2012 Neil, C. J., Nguyen, T. H., Mahadavan, G., Chapman, M., Kucia, A. M., Stansborough, J., . . . Horowitz, J. D. (2012). LV functional recovery from Tako-Tsubo cardiomyopathy is incomplete after 3 months: evidence from 2D speckle-tracking echocardiography. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Munchen, GERMANY: OXFORD UNIV PRESS. 2012 Liu, S., Ngo, D. T., Chirkov, Y. Y., Sheikh, A. R., Licari, G., Stewart, S., & Horowitz, J. D. (2012). Brain Natriuretic Peptide (BNP) Suppresses Neutrophil Superoxide Release: Attenuation in Patients with Congestive Heart Failure (CHF). Poster session presented at the meeting of CIRCULATION. LIPPINCOTT WILLIAMS & WILKINS. 2012 Procter, N. E. K., Ball, J., Carrington, M., Nguyen, T. H., Ngo, D., Chirkov, Y. Y., . . . Horowitz, J. D. (2012). Determinants of platelet response to nitric oxide in association with atrial fibrillation: evidence for an acute suppression of response. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Munchen, GERMANY: OXFORD UNIV PRESS. 2012 Stewart, S., Carrington, M. J., Marwick, T. H., Davidson, P. M., Macdonald, P., Horowitz, J. D., . . . Scuffham, P. (2012). Impact of home versus clinic based management of chronic heart failure: the which heart failure intervention is most cost-effective & consumer friendly in reducing hospital care (WHICH?) multicentre. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Munchen, GERMANY: OXFORD UNIV PRESS. 2012 Bullen, M. L., Miller, A. A., Drummond, G. R., Sobey, C. G., Stasch, J. -P., Chirkov, Y. Y., . . . Kemp-Harper, B. K. (2012). Nitric Oxide-Independent Stimulators of Soluble Guanylyl Cyclase Circumvent Platelet Nitric Oxide Resistance in Hypercholesterolemic Mice. Poster session presented at the meeting of CIRCULATION. LIPPINCOTT WILLIAMS & WILKINS. 2011 Nguyen, T., Neil, C., Chan, A., & Horowitz, J. (2011). Prolonged mobilization of endothelial progenitor cells post takotsubo cardiomyopathy. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. OXFORD UNIV PRESS. 2011 Sverdlov, A. L., Ngo, D. T. M., Chirkov, Y. Y., & Horowitz, J. D. (2011). Insights into the initiation of aortic stenosis: roles of ACE-inhibitors and vitamin D. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. OXFORD UNIV PRESS. 2011 Chan, W. P. A., Sverdlov, A. L., Ngo, D. T., Chirkov, Y. Y., & Horowitz, J. D. (2011). Does oral contraceptive therapy induce platelet nitric oxide resistance?. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. OXFORD UNIV PRESS. 2011 Ngo, D. T. M., Chan, W. P. A., Sverdlov, A. L., & Horowitz, J. D. (2011). Determinants and cardiovascular correlates of vitamin D deficiency in australian women. Poster session presented at the meeting of AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. AMER THORACIC SOC. 2011 Ngo, D. T. M., Chan, W. P. A., Sverdlov, A. L., & Horowitz, J. D. (2011). Determinants and cardiovascular correlates of vitamin D deficiency in australian women. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. OXFORD UNIV PRESS. 2011 Sverdlov, A. L., Ngo, D. T. M., Chirkov, Y. Y., & Horowitz, J. D. (2011). Insights into the initiation of aortic stenosis: roles of ACE-inhibitors and vitamin D. Poster session presented at the meeting of AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. AMER THORACIC SOC. 2010 Kucia, A. M., Neil, C. J. A., Nguyen, T. H., Beltrame, J. F., Arstall, M. A., & Horowitz, J. D. (2010). Evolution of ECG changes in tako tsubo cardiomyopathy: arrhythmias first, QT prolongation later?. Poster session presented at the meeting of EUROPEAN HEART JOURNAL. Stockholm, SWEDEN: OXFORD UNIV PRESS. 2009 Sverdlov, A. L., Ngo, D. T., Nightingale, A. K., Rajendran, S., Heresztyn, T., & Horowitz, J. D. (2009). Plasma concentrations of asymmetric dimethylarginine (ADMA) predict LV mass independent of afterload. Poster session presented at the meeting of Abstracts of the 82nd Scientific Session of the American Heart Association, as published in Circulation. Orlando, FL: American Heart Association. 2008 Chirkov, Y. Y., De Sciscio, M., Sverdlov, A. L., Leslie, S., & Horowitz, J. D. (2008). Is there a pharmacological hydralazine/nitrate interaction in chronic heart failure?. Poster session presented at the meeting of Abstracts of ESC Congress 2008, as published in European Heart Journal. Munich, Germany: Oxford University Press.
WoS1 -
Report for External Bodies
Year Citation 2002 Beltrame, J. F., & Horowitz, J. D. (2002). Safety of N-Acetylcysteine in Acute Coronary Syndromes. -
Internet Publications
Year Citation 2017 Beltrame, J. F. (2017). Early Use of N-acetylcysteine With Nitrate Therapy in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Segment-Elevation Myocardial Infarction Reduces Myocardial Infarct Size - The NACIAM Trial (N-acetylcysteine in Acute Myocardial Infarction) Podcastt.
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2022 Co-Supervisor Investigating cardiovascular complications of diabetes Doctor of Philosophy Doctorate Full Time Mr Getandale Zeleke Negera -
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2015 - 2018 Principal Supervisor Inter-Individual Variability in Platelet Adenylate and Soluble Guanylate Cyclase Signaling: Therapeutic Perspectives Doctor of Philosophy Doctorate Full Time Mr Md Hasan Imam 2015 - 2022 Principal Supervisor Takotsubo Syndrome: Precipitants, Clinical Course and Emerging Treatments Doctor of Philosophy Doctorate Part Time Mr Gao Jing Ong 2014 - 2016 Principal Supervisor Endothelial Dysfunction and Inflammatory Activation in Patients with Bicuspid Aortic Valves Master of Clinical Science Master Part Time Mr Matthew John Chapman 2014 - 2019 Principal Supervisor Nitrosative Stress and the Pathogenesis of Takotsubo Syndrome: Insights from a Novel Female Rat Model Doctor of Philosophy Doctorate Full Time Mr Sven Yuri Surikow 2014 - 2018 Principal Supervisor Interactions between Cardiac Resynchronisation Therapy and Amelioration of Peripheral Vascular Dysfunction: Impact upon Outcomes Doctor of Philosophy Doctorate Full Time Dr Chukwudiebube Nnanna Ajaero 2012 - 2017 Co-Supervisor A Pharmacological Approach Towards Myocardial Protection: New Perspectives in Acute and Chronic Cardiac Disease Doctor of Philosophy Doctorate Full Time Dr Cher-Rin Chong 2012 - 2015 Principal Supervisor Natural History and Pathogenesis of Takotsubo Cardiomyopathy Doctor of Philosophy Doctorate Full Time Dr Kuljit Singh 2011 - 2015 Principal Supervisor Effects of Nitrite and Nitroxyl on Human Vascular and Platelet Function Doctor of Philosophy Doctorate Full Time Dr Rustem Dautov 2010 - 2015 Principal Supervisor Variability of Nitric Oxide Signalling in Atrial Fibrillation: Potential Modulation Doctor of Philosophy Doctorate Part Time Mr Nathan Edward Kevin Procter 2010 - 2015 Principal Supervisor Impaired Tissue Responsiveness to B-Type Natriuretic Peptide in Heart Failure: Biochemical Bases Doctor of Philosophy Doctorate Full Time Dr Saifei Liu 2009 - 2014 Principal Supervisor Tako-Tsubo (Stress) Cardiomyopathy: Pathophysiology and Natural History Doctor of Philosophy Doctorate Full Time Dr Christopher Neil 2009 - 2016 Principal Supervisor Post-P2Y 12-Receptor Signalling Mechanisms and Platelet Responses to Clopidogrel Doctor of Philosophy Doctorate Full Time Dr Nicola Hurst 2008 - 2012 Principal Supervisor The Role of Oxidant Stress in a Cellular Model of Aortic Valve Cell Calcification Master of Medical Science Master Part Time Dr Navin S Kanagasingam 2008 - 2012 Co-Supervisor Implications of Catecholamine-related Pathophysiology in Cardiomyopathy Doctor of Philosophy Doctorate Full Time Dr Ha Thanh Nguyen 2006 - 2016 Principal Supervisor Mechanisms of dyspnoea and poor exercise tolerance in a representative cohort of elderly patients with a relatively normal ejection fraction on echocardiography Doctor of Philosophy Doctorate Full Time Dr Gnanadevan Mahadevan 2006 - 2013 Principal Supervisor Cardiovascular Risk Assessment in Women: Impact of Ageing, Polycystic Ovarian Syndrome and Menopause on Nitric Oxide Signalling Doctor of Philosophy Doctorate Full Time Dr Alicia Chan 2005 - 2012 Principal Supervisor Pathogenesis of Aortic Stenosis: Implications Regarding Impairment of Nitric Oxide Signalling Doctor of Philosophy Doctorate Full Time Dr Aaron Sverdlov 2005 - 2009 Principal Supervisor Platelet and Endothelial Function: Polycystic Ovary Syndrome and the Renin-Angiotensin System Doctor of Philosophy Doctorate Full Time Dr Sharmalar Rajendran 2004 - 2007 Co-Supervisor Induction of Myocardial Ischaemia: A Comparison of Pharmacologic and Physiologic Stress Myocardial Perfusion Imaging Master of Medical Science Master Full Time Dr Ha Thanh Nguyen 2004 - 2008 Principal Supervisor Potential Utility of Changes in Entropy as an Adjunct to the Electrocardiography Diagnosis of Reversible Myocardial Ischaemia Master of Medical Science Master Full Time Dr Jinlin Zhao 2003 - 2007 Principal Supervisor Pathogenesis of Aortic Valve Stenosis: Bench to Bedside Approach Doctor of Philosophy Doctorate Full Time APrf Doan Ngo 2003 - 2007 Principal Supervisor Effect of Nitric Oxide on Aortic Valve Calcification in vitro Master of Clinical Science Master Full Time Mr Xiang Hua 2002 - 2007 Co-Supervisor Vasomotor and Anti-Oxidant Effects of Anti-Ischaemic Therapies. Doctor of Philosophy Doctorate Full Time Miss Elizabeth Liberts 2000 - 2005 Co-Supervisor TISSUE RESPONSES TO NITRIC OXIDE DONORS: STUDIES IN PLATELETS AND IN MYOCARDIUM Doctor of Philosophy Doctorate Full Time APrf Matthew Worthley 1998 - 2003 Principal Supervisor Pathophysiological and platelet anti-aggregatory effects of nitric oxide Doctor of Philosophy Doctorate Full Time Dr Andrew Holmes 1998 - 2002 Principal Supervisor Tolerance and Resistance to Organic Nitrates in Human Blood Vessels Doctor of Philosophy Doctorate Full Time Dr Peter Sage
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