Carl Adrian Campugan
Higher Degree by Research Candidate
School of Biomedicine
Faculty of Health and Medical Sciences
Carl Adrian Campugan, is a PhD student jointly between the Faculty of Health and Medical Sciences at the University of Adelaide (Australia) and the Faculty of Engineering at the University of Nottingham (United Kingdom). Previously majoring in reproductive biology, his PhD bridges two disciplines in an effort to better understand the viability of modern optical techniques as a non-invasive diagnostic tool for predicting reproductive success. His research topics aim to use manipulated light as a tool to trap/hold tracers to characterize properties of the female gamete or the fertilised embryo. Supported by a transdisciplinary team of supervisors, he hopes to shed light on how understanding the microrheological properties of cells and their surroundings may be used as a diagnostic indicator of reproductive health and viability, with relevance to In Vitro fertilisation.
Carl's research involves the use of trapping techniques to detect, assess, and characterize biomechanical properties of the female gamete and the fertilised embryo. A joint student between two universities, he hopes to implement and bridge his understanding of the two schools to determine the viability of optical techniques as non-invasive diagnostic tools. In better understanding its' validity, he hopes that these diagnostic methods may be of use within the clinic to improve reproductive success (i.e. fertility, pregnancy, and child birth rates) with relevance to In Vitro fertilisation.
His research interests specifically lies in understanding how robust non-invasive optical techniques, like optical tweezers, can be implemented within the field of reproduction to better understand the interaction complex flow dynamics of the soft matter that make up cells and their supporting mediums. In addition, using his expertise as a reproductive biologist, he aims to match these microrheological characteristics with fertility rate, pre-implantation embryo development, implantation rate, pregnancy rate, and pregnancy success.
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Language Competencies
Language Competency English Can read, write, speak, understand spoken and peer review Tagalog Can read, write, speak and understand spoken -
Education
Date Institution name Country Title 2018 - 2019 University of Adelaide Australia Honours Degree of Bachelor of Health and Medical Sciences 2015 - 2017 University of Adelaide Australia Bachelor of Health Sciences -
Research Interests
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Journals
Year Citation 2022 Campugan, C. A., Lim, M., Chow, D. J. X., Tan, T. C. Y., Li, T., Saini, A. A., . . . Dunning, K. R. (2022). The effect of discrete wavelengths of visible light on the developing murine embryo. Journal of Assisted Reproduction and Genetics, 39(8), 1825-1837.
Scopus4 WoS3 Europe PMC12022 Tan, C., Mahbub, S., Campbell, J., Habibalahi, A., Campugan, C., Rose, R., . . . Dunning, K. (2022). Non-invasive, label-free optical analysis to detect aneuploidy within the inner cell mass of the preimplantation embryo. Human Reproduction, 37(1), 14-29.
Scopus19 WoS15 Europe PMC112020 Campugan, C. A., Dunning, K. R., & Dholakia, K. (2020). Optical manipulation: a step change for biomedical science. Contemporary Physics, 61(4), 1-18.
Scopus7 WoS3 -
Conference Papers
Year Citation 2019 Dunning, K. R., Campugan, C., Tan, C., Mahbub, S., Goldys, E., Thompson, J., . . . Mustafa, S. (2019). Hyperspectral imaging of the early embryo: can it detect chromosome abnormalities and predict IVF success?. In Label-free Biomedical Imaging and Sensing (LBIS) Vol. 10890:108900I (pp. 1-3). online: SPIE.
Scopus2 WoS1 -
Conference Items
2021 Healthy Development Adelaide (HDA) and the Channel 7 Children’s Research Foundation (CRF) PhD Excellence Award
2020 Joint PhD Scholarship With the University of Nottingham
2023
- Science in the Park (Wollaton Hall and Park)
Demonstrator – Provided demonstration of various optical experiments to the general public as part of the Optics and Photonics Group (University of Nottingham)
2022
- National Youth Science Forum Outreach Program
Laboratory Practical Demonstrator – Provided introductory laboratory demonstration of basic embryology for 60 Year 12 students.
- Year 12 Work Experience
Supervisor – Coordinated hands-on laboratory experiments for Year 12 student.
2021
- National Youth Science Forum Outreach Program
Laboratory Practical Demonstrator – Provided introductory laboratory demonstration of basic embryology for 60 Year 12 students.
- Year 12 Work Experience
Supervisor – Coordinated hands-on laboratory experiments for Year 12 student.
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