Dr Beverly Muhlhausler

Beverly Muhlhausler
Senior Research Fellow
School of Agriculture, Food and Wine
Faculty of Sciences

I am a NHMRC Career Development Award Fellow (Level 2) and lead the Obesity and Metabolic Health Division of the FOODplus Research Centre at the University of Adelaide.My work on the impact of maternal overnutrition on the programming of obesity and metabolic disease has made a significant contribution to current understanding of how exposure to maternal obesity and/or an excess nutrient supply before birth acts to alter the development of key systems involved in the regulation of energy balance. A key focus of my current research is identifying and testing nutritional interventions which can be applied during the perinatal period to improve metabolic health through the life-course, and I am currently leading basic science projects and clinical trials in this area. Since 2008, my work has included a specific focus on the role of maternal omega-3 fatty acid supplementation in determining growth and metabolic health of the infant and child, and I have published 15 original research papers and 4 reviews in the fatty acid field since 2012.

Connect With Me

Dr Beverly Muhlhausler

I am a NHMRC Career Development Award Fellow (Level 2) and lead the Obesity and Metabolic Health Division of the FOODplus Research Centre at the University of Adelaide.My work on the impact of maternal overnutrition on the programming of obesity and metabolic disease has made a significant contribution to current understanding of how exposure to maternal obesity and/or an excess nutrient supply before birth acts to alter the development of key systems involved in the regulation of energy balance. A key focus of my current research is identifying and testing nutritional interventions which can be applied during the perinatal period to improve metabolic health through the life-course, and I am currently leading basic science projects and clinical trials in this area. Since 2008, my work has included a specific focus on the role of maternal omega-3 fatty acid supplementation in determining growth and metabolic health of the infant and child, and I have published 15 original research papers and 4 reviews in the fatty acid field since 2012.

Appointments

Date Position Institution name
2017 - 2010 NHMRC Peter Doherty Postdoctoral Fellow, Sansom Institute for Health Research, University of South Australia
2017 President Australia and New Zealand Society for the Developmental Origins of Health and Disease
2015 National Health and Medical Research Council (NHMRC) Career Development Award Fellow (Level 2) The University of Adelaide
2014 Treasurer International Society for the Study of Fatty Acids and Lipids
2014 - 2017 Secretary Australia and New Zealand Society for the Developmental Origins of Health and Disease
2014 Deputy Director, FOODplus Research Centre The University of Adelaide
2011 - 2015 National Health and Medical Research Council (NHMRC) Career Development Award Fellow The University of Adelaide
2010 Head, Obesity and Metabolic Health Division, FOODplus Research Centre The University of Adelaide,
2006 - 2007 Postdoctoral Fellow University of South Australia

Language Competencies

Language Competency
German Can read, write, speak, understand spoken and peer review

Education

Date Institution name Country Title
2012 - 2006 The University of Adelaide Australia PhD
1997 - 2001 The University of Adelaide Australia BSc (First Class Honours)

Keywords

Endocrinology & Metabolism, Medical and Health Sciences, Medical Biochemistry: Lipids, Neurosciences, Nutrition and Dietetics, Nutritional Physiology, Obstetrics and Gynaecology, Paediatrics, Physiology

Journals

Date Citation
2017 Kanakri,K, Carragher,J, Hughes,R, Muhlhausler,B, Gibson,R, 2017, A reduced cost strategy for enriching chicken meat with omega-3 long chain polyunsaturated fatty acids using dietary flaxseed oil, British Poultry Science, 1-7 10.1080/00071668.2017.1293798
2017 Mühlhäusler,BS, 2017, Variability in the cardiometabolic effects of ω-3 long-chain PUFAs: background diet, timing, and genetics., The American journal of clinical nutrition, 105, 5, 1029-1030 10.3945/ajcn.117.155739
2017 Symon,B, Crichton,GE, Muhlhausler,B, 2017, Does the early introduction of solids promote obesity?, Singapore medical journal, - 10.11622/smedj.2017024
2017 Peter,R, Gugusheff,J, Wooldridge,A, Gatford,K, Muhlhausler,B, 2017, Placental restriction in multi-fetal pregnancies and between-twin differences in size at birth alter neonatal feeding behaviour in the sheep, Journal of Developmental Origins of Health and Disease, 8, 3, 1-13 10.1017/S2040174417000137
2017 Toop,CR, Muhlhausler,BS, O'Dea,K, Gentili,S, 2017, Impact of perinatal exposure to sucrose or high fructose corn syrup (HFCS-55) on adiposity and hepatic lipid composition in rat offspring., The Journal of physiology, - 10.1113/jp274066
2017 Gatford,KL, Muhlhausler,B, Huang,L, Sim,PS-L, Roberts,CT, Veldhuis,JD, Chen,C, 2017, Rising maternal circulating GH during murine pregnancy suggests placental regulation., Endocrine connections, - 10.1530/ec-17-0032
2017 Huynh,D, Condo,D, Gibson,R, Makrides,M, Muhlhausler,B, Zhou,S, 2017, Comparison of breast-milk iodine concentration of lactating women in Australia pre and post mandatory iodine fortification, Public Health Nutrition, 2, 1, 12-17 10.1017/S1368980016002032
2017 Bazargan,M, Foster,D, Davey,A, Muhlhausler,B, 2017, Rosiglitazone Metabolism in Human Liver Microsomes Using a Substrate Depletion Method, Drugs in R and D, 17, 1, 189-198 10.1007/s40268-016-0166-4
2017 Kanakri,K, Carragher,J, Muhlhausler,B, Hughes,R, Gibson,R, 2017, In ovo exposure to omega-3 fatty acids does not enhance omega-3 long-chain polyunsaturated fatty acid metabolism in broiler chickens, Journal of Developmental Origins of Health and Disease, 1-9 10.1017/S2040174417000216
2016 Prescott,S, Allen,K, Armstrong,K, Collins,C, Dickinson,H, Gardiner,K, Jacka,F, Jasoni,C, Moore,T, Moritz,K et al, 2016, The establishment of DOHaD working groups in Australia and New Zealand, Journal of Developmental Origins of Health and Disease, 7, 5, 433-439 10.1017/S2040174416000167
2016 Clifton,V, Moss,T, Wooldridge,A, Gatford,K, Liravi,B, Kim,D, Muhlhausler,B, Morrison,J, Davies,A, De Matteo,R et al, 2016, Development of an experimental model of maternal allergic asthma during pregnancy, Journal of Physiology, 594, 5, 1311-1325 10.1113/jp270752
2016 Gugusheff,J, Sim,P, Kheng,A, Gentili,S, Al-Nussairawi,M, Brand-Miller,J, Muhlhausler,B, 2016, The effect of maternal and post-weaning low and high glycaemic index diets on glucose tolerance, fat deposition and hepatic function in rat offspring, Journal of Developmental Origins of Health and Disease, 7, 3, 320-329 10.1017/S2040174415007965
2016 Dickinson,H, Moss,T, Gatford,K, Moritz,K, Akison,L, Fullston,T, Hryciw,D, Maloney,C, Morris,M, Wooldridge,A et al, 2016, A review of fundamental principles for animal models of DOHaD research: an Australian perspective, Journal of Developmental Origins of Health and Disease, 7, 5, 449-472 10.1017/S2040174416000477
2016 Hodyl,N, Muhlhausler,B, 2016, Novel insights, challenges and practical implications of DOHaD-omics research, Medical Journal of Australia, 204, 3, 108-110 10.5694/mja14.01626
2016 Carragher,JF, Muhlhausler,BS, Geier,MS, House,JD, Hughes,RJ, Gibson,RA, 2016, Effect of dietary ALA on growth rate, feed conversion ratio, mortality rate and breast meat omega-3 LCPUFA content in broiler chickens, Animal Production Science, 56, 5, 815-823 10.1071/AN14743
2016 Bazargan,M, Foster,D, Muhlhausler,B, Morrison,J, McMillen,C, Davey,A, 2016, Limited fetal metabolism of rosiglitazone: elimination via the maternal compartment in the pregnant ewe, Reproductive Toxicology, 61, 162-168 10.1016/j.reprotox.2016.04.008
2016 Bischof,R, Clifton,V, Wooldridge,A, Gatford,K, Liravi,B, Kim,D, Muhlhausler,B, Morrison,J, Davies,A, Dematteo,R et al, 2016, A SHEEP MODEL TO EXAMINE THE EFFECTS OF MATERNAL ASTHMA ON FETAL OUTCOMES, RESPIROLOGY, 21, 56-56
2016 Kanakri,K, Muhlhausler,B, Carragher,J, Gibson,R, Barekatain,R, Dekoning,C, Drake,K, Hughes,R, 2016, Relationship between the fatty acid composition of uropygial gland secretion and blood of meat chickens receiving different dietary fats, Animal Production Science, Online, A-F 10.1071/AN16268
2016 Pidsley,R, Zotenko,E, Peters,T, Lawrence,M, Risbridger,G, Molloy,P, Van Djik,S, Muhlhausler,B, Stirzaker,C, Clark,S et al, 2016, Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling, Genome Biology, 17, 1, 208-1-208-17 10.1186/s13059-016-1066-1
2016 van Dijk,S, Zhou,J, Peters,T, Buckley,M, Sutcliffe,B, Oytam,Y, Gibson,R, McPhee,A, Yelland,L, Makrides,M et al, 2016, Effect of prenatal DHA supplementation on the infant epigenome: results from a randomized controlled trial, Clinical Epigenetics, 8, 1, 114-1-114-13 10.1186/s13148-016-0281-7
2016 Vithayathil,M, Gugusheff,J, Gibson,R, Ong,Z, Muhlhausler,B, 2016, Effect of a maternal cafeteria diet on the fatty acid composition of milk and offspring red blood cells, Prostaglandins Leukotrienes and Essential Fatty Acids, 109, 58-65 10.1016/j.plefa.2016.03.016
2016 Leghi,G, Muhlhausler,B, 2016, The effect of n-3 LCPUFA supplementation on oxidative stress and inflammation in the placenta and maternal plasma during pregnancy, Prostaglandins Leukotrienes and Essential Fatty Acids, 113, 33-39 10.1016/j.plefa.2016.08.010
2016 Condo,D, Huyhn,D, Anderson,A, Skeaff,S, Ryan,P, Makrides,M, Mühlhaüsler,B, Zhou,S, 2016, Iodine status of pregnant women in South Australia after mandatory iodine fortification of bread and the recommendation for iodine supplementation, Maternal and Child Nutrition, e12410-e12410 10.1111/mcn.12410
2016 Gugusheff,J, Bae,S, Rao,A, Clarke,I, Poston,L, Taylor,P, Coen,C, Muhlhausler,B, 2016, Sex and age-dependent effects of a maternal junk food diet on the mu-opioid receptor in rat offspring, Behavioural Brain Research, 301, 124-131 10.1016/j.bbr.2015.12.027
2016 Do,T, Muhlhausler,B, Box,A, Able,A, 2016, Enrichment of antioxidant capacity and vitamin E in pita made from barley, Journal of Food Science, 81, 3, H777-H785 10.1111/1750-3841.13218
2015 Gugusheff,J, Ong,Z, Muhlhausler,B, 2015, The early origins of food preferences: targeting the critical windows of development, FASEB Journal, 29, 2, 365-373 10.1096/fj.14-255976
2015 Do,TTD, Cozzolino,D, Muhlhausler,B, Box,A, Able,AJ, 2015, Effect of malting on antioxidant capacity and vitamin E content in different barley genotypes, Journal of the Institute of Brewing, 121, 4, 531-540 10.1002/jib.271
2015 Do,T, Cozzolino,D, Muhlhausler,B, Box,A, Able,A, 2015, Antioxidant capacity and vitamin E in barley: Effect of genotype and storage, Food Chemistry, 187, 65-74 10.1016/j.foodchem.2015.04.028
2015 Van Dijk,S, Molloy,P, Varinli,H, Morrison,J, Muhlhausler,B, Buckley,M, Clark,S, McMillen,I, Noakes,M, Samaras,K et al, 2015, Epigenetics and human obesity, International Journal of Obesity, 39, 1, 85-97 10.1038/ijo.2014.34
2015 van Dijk,S, Tellam,R, Morrison,J, Muhlhausler,B, Molloy,P, 2015, Recent developments on the role of epigenetics in obesity and metabolic disease, Clinical Epigenetics, 7, 1, 66-1-66-13 10.1186/s13148-015-0101-5
2015 Wood,KE, Mantzioris,E, Gibson,RA, Ramsden,CE, Muhlhausler,BS, 2015, The effect of modifying dietary LA and ALA intakes on omega-3 long chain polyunsaturated fatty acid (n-3 LCPUFA) status in human adults: a systematic review and commentary, Prostaglandins Leukotrienes and Essential Fatty Acids, 95, April, 47-55 10.1016/j.plefa.2015.01.001
2015 Huynh,D, Zhou,SJ, Gibson,R, Palmer,L, Muhlhausler,B, 2015, Validation of an optimized method for the determination of iodine in human breast milk by inductively coupled plasma mass spectrometry (ICPMS) after tetramethylammonium hydroxide extraction, Journal of Trace Elements in Medicine and Biology, 29, 75-82 10.1016/j.jtemb.2014.07.005
2015 Liu,G, Mühlhäusler,BS, Gibson,RA, 2015, Evaluation of contamination associated with current blood spot technology for determining the fatty acid status of individuals, European Journal of Lipid Science and Technology, 117, 8, 1280-1286 10.1002/ejlt.201400470
2014 Rattanatray,L, Muhlhausler,B, Nicholas,L, Morrison,J, McMillen,I, 2014, Impact of maternal overnutrition on gluconeogenic factors and methylation of the phosphoenolpyruvate carboxykinase promoter in the fetal and postnatal liver, Pediatric Research, 75, 1, 14-21 10.1038/pr.2013.178
2014 Muhlhausler,B, Gibson,R, Yelland,L, Makrides,M, 2014, Heterogeneity in cord blood DHA concentration: towards an explanation, Prostaglandins, leukotrienes, and essential fatty acids, 91, 4, 135-140 10.1016/j.plefa.2014.07.013
2014 Ong,Z, Muhlhausler,B, 2014, Consuming a low-fat diet from weaning to adulthood reverses the programming of food preferences in male, but not in female, offspring of 'junk food'-fed rat dams, Acta Physiologica, 210, 1, 127-141 10.1111/apha.12132
2014 Toop,C, Muhlhausler,B, O'Dea,K, Gentili,S, 2014, Consumption of sucrose, but not high fructose corn syrup, leads to increased adiposity and dyslipidaemia in the pregnant and lactating rat, Journal of Developmental Origins of Health and Disease, 6, 1, 38-46 10.1017/S2040174414000610
2014 Muhlhausler,BS, Vithayathil,MA, 2014, Impact of maternal obesity on offspring adipose tissue: lessons for the clinic, Expert Review of Endocrinology and Metabolism, 9, 6, 615-627 10.1586/17446651.2014.956088
2014 Muhlhausler,B, 2014, Fatty acids in the infant diet: size matters, British Journal of Nutrition, 111, 2, 193-193 10.1017/S0007114513002365
2014 Liu,G, Muehlhaeusler,B, Gibson,R, 2014, A method for long term stabilisation of long chain polyunsaturated fatty acids in dried blood spots and its clinical application, Prostaglandins, Leukotrienes and Essential Fatty Acids, 91, 6, 251-260 10.1016/j.plefa.2014.09.009
2014 Lee,A, Shandala,T, Nguyen,L, Muhlhausler,B, Chen,K, Howe,P, Xian,C, 2014, Effects of resveratrol supplementation on bone growth in young rats and microarchitecture and remodeling in ageing rats, Nutrients, 6, 12, 5871-5887 10.3390/nu6125871
2014 Wood,K, Lau,A, Mantzioris,E, Gibson,R, Ramsden,C, Muhlhausler,B, 2014, A low omega-6 polyunsaturated fatty acid (n-6 PUFA) diet increases omega-3 (n-3) long chain PUFA status in plasma phospholipids in humans, Prostaglandins, Leukotrienes and Essential Fatty Acids, 90, 4, 133-138 10.1016/j.plefa.2013.12.010
2014 Lie,S, Hui,M, McMillen,I, Muhlhausler,B, Posterino,G, Dunn,S, Wang,K, Botting,K, Morrison,J, 2014, Exposure to rosiglitazone, a PPAR-γ agonist, in late gestation reduces the abundance of factors regulating cardiac metabolism and cardiomyocyte size in the sheep fetus, American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 306, 6, R429-R437 10.1152/ajpregu.00431.2013
2014 Gugusheff,J, Ong,Z, Muhlhausler,B, 2014, Naloxone treatment alters gene expression in the mesolimbic reward system in 'junk food' exposed offspring in a sex-specific manner but does not affect food preferences in adulthood, Physiology and Behavior, 133, 14-21 10.1016/j.physbeh.2014.04.007
2013 Gugusheff,J, Vithayathil,M, Ong,Z, Muhlhausler,B, 2013, The effects of prenatal exposure to a 'junk food' diet on offspring food preferences and fat deposition can be mitigated by improved nutrition during lactation, Journal of Developmental Origins of Health and Disease, 4, 5, 348-357 10.1017/S2040174413000330
2013 Tu,W, Muhlhausler,B, James,M, Stone,D, Gibson,R, 2013, Dietary alpha-linolenic acid does not enhance accumulation of omega-3 long-chain polyunsaturated fatty acids in barramundi (Lates calcarifer), Comparative Biochemistry and Physiology B- Biochemistry and Molecular Biology, 164, 1, 29-37 10.1016/j.cbpb.2012.10.001
2013 Nicholas,L, Rattanatray,L, MacLaughlin,S, Ozanne,S, Kleemann,D, Walker,S, Morrison,J, Zhang,S, Muhlhausler,B, Martin-Gronert,M et al, 2013, Differential effects of maternal obesity and weight loss in the periconceptional period on the epigenetic regulation of hepatic insulin-signaling pathways in the offspring, The FASEB Journal, 27, 9, 3786-3796 10.1096/fj.13-227918
2013 Muhlhausler,B, Ailhaud,G, 2013, Omega-6 polyunsaturated fatty acids and the early origins of obesity, Current Opinion in Endocrinology, Diabetes and Obesity, 20, 1, 56-61 10.1097/MED.0b013e32835c1ba7
2013 Neale,E, Muhlhausler,B, Probst,Y, Batterham,M, Fernandez,F, Tapsell,L, 2013, Short-term effects of fish and fish oil consumption on total and high molecular weight adiponectin levels in overweight and obese adults, Metabolism-clinical and Experimental, 62, 5, 651-660 10.1016/j.metabol.2012.10.014
2013 Muhlhausler,B, Bloomfield,F, Gillman,M, 2013, Whole animal experiments should be more like human randomized controlled trials, PLoS Biology, 11, 2, 1-6 10.1371/journal.pbio.1001481
2013 Ong,Z, Wanasuria,A, Lin,M, Hiscock,J, Muhlhausler,B, 2013, Chronic intake of a cafeteria diet and subsequent abstinence. Sex-specific effects on gene expression in the mesolimbic reward system, Appetite, 65, 189-199 10.1016/j.appet.2013.01.014
2013 Tu,W, Muhlhausler,B, Yelland,L, Gibson,R, 2013, Correlations between blood and tissue omega-3 LCPUFA status following dietary ALA intervention in rats, Prostaglandins Leukotrienes and Essential Fatty Acids, 88, 1, 53-60 10.1016/j.plefa.2012.04.005
2013 Wood,K, Mantzioris,E, Gibson,R, Muhlhausler,B, 2013, Incorporating macadamia oil and butter to reduce dietary omega-6 polyunsaturated fatty acid intake, Nutrition & Dietetics, 70, 2, 94-100 10.1111/j.1747-0080.2012.01636.x
2013 Gray,B, Muhlhausler,B, Davies,P, Vitetta,L, 2013, Liver enzymes but not free fatty acid levels predict markers of insulin sensitivity in overweight and obese, nondiabetic adults, Nutrition Research, 33, 10, 781-788 10.1016/j.nutres.2013.07.019
2013 Muhlhausler,B, Gugusheff,J, Ong,Z, Vithayathil,M, 2013, Nutritional approaches to breaking the intergenerational cycle of obesity, Canadian Journal of Physiology and Pharmacology, 91, 6, 421-428 10.1139/cjpp-2012-0353
2013 Gugusheff,J, Ong,Z, Muhlhausler,B, 2013, A maternal 'junk-food' diet reduces sensitivity to the opioid antagonist naloxone in offspring postweaning, The FASEB Journal, 27, 3, 1275-1284 10.1096/fj.12-217653
2013 Lie,S, Duffield,J, McMillen,I, Morrison,J, Ozanne,S, Pilgrim,C, Muhlhausler,B, 2013, The effect of placental restriction on insulin signaling and lipogenic pathways in omental adipose tissue in the postnatal lamb, Journal of Developmental Origins of Health and Disease, 4, 5, 421-429 10.1017/S2040174413000202
2013 Muhlhausler,B, Gugusheff,J, Ong,Z, Vithayathil,M, 2013, Pregnancy, obesity and insulin resistance: maternal overnutrition and the target windows of fetal development, Hormone Molecular Biology and Clinical Investigation, 15, 1, 25-36 10.1515/hmbci-2013-0029
2013 Molloy,P, Samaras,K, Muhlhausler,B, McMillen,C, 2013, Chasing the “ghost in our genes” to beat obesity, Medical Journal of Australia, 198, 4, 182-182 10.5694/mja13.10098
2012 Tu,W, Muhlhausler,B, James,M, Stone,D, Gibson,R, 2012, An alternative n-3 fatty acid elongation pathway utilising 18:3n-3 in barramundi (Lates calcarifer), Biochemical and Biophysical Research Communications, 423, 1, 176-182 10.1016/j.bbrc.2012.05.110
2012 Ong,Z, Gugusheff,J, Muhlhausler,B, 2012, Perinatal overnutrition and the programming of food preferences: pathways and mechanisms, Journal of Developmental Origins of Health and Disease, 3, 5, 299-308 10.1017/S204017441200030X
2012 Mühlhäusler,B, 2012, Fat on the brain, Journal of Physiology, 590, 17, 4121-4121 10.1113/jphysiol.2012.239491
2012 Fong,L, Muhlhausler,B, Gibson,R, Xian,C, 2012, Perinatal maternal dietary supplementation of ω3-fatty acids transiently affects bone marrow microenvironment, osteoblast and osteoclast formation, and bone mass in male offspring, Endocrinology, 153, 5, 2455-2465 10.1210/en.2011-1917
2012 Tu,W, Cook-Johnson,R, James,M, Muhlhausler,B, Stone,D, Gibson,R, 2012, Barramundi (Lates calcarifer) desaturase with Δ6/Δ8 dual activities, Biotechnology Letters, 34, 7, 1283-1296 10.1007/s10529-012-0891-x
2011 Muhlhausler,B, Gibson,R, Makrides,M, 2011, The effect of maternal omega-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA) supplementation during pregnancy and/or lactation on body fat mass in the offspring: A systematic review of animal studies, Prostaglandins Leukotrienes and Essential Fatty Acids, 85, 2, 83-88 10.1016/j.plefa.2011.04.027
2011 Muhlhausler,B, Miljkovic,D, Fong,L, Xian,C, Duthoit,E, Gibson,R, 2011, Maternal omega-3 supplementation increases fat mass in male and female rat offspring, Frontiers in Genetics, 2, 48, 1-10 10.3389/fgene.2011.00048
2011 Gibson,R, Muhlhausler,B, Makrides,M, 2011, Conversion of linoleic acid and alpha-linolenic acid to long chain polyunsaturated fatty acids (LCPUFAs), with a focus on pregnancy, lactation and the first 2 years of life, Maternal and Child Nutrition, 7, Suppl 2, 17-26 10.1111/j.1740-8709.2011.00299.x
2011 Ong,Z, Muhlhausler,B, 2011, Maternal "junk-food" feeding of rat dams alters food choices and development of the mesolimbic reward pathway in the offspring, The FASEB Journal, 25, 7, 2167-2179 10.1096/fj.10-178392
2011 Bazargan,M, Davey,A, Muhlhausler,B, Morrison,J, McMillen,I, Foster,D, 2011, Simple HPLC method for determination of rosiglitazone in sheep plasma and amniotic fluid and its application in a pregnant sheep model, Journal of Pharmaceutical and Biomedical Analysis, 55, 2, 360-365 10.1016/j.jpba.2011.01.026
2011 Muhlhausler,B, Hancock,S, Bloomfield,F, Harding,R, 2011, Are twins growth restricted?, Pediatric Research, 70, 2, 117-122 10.1203/PDR.0b013e31821f6cfd
2011 Muhlhausler,B, Ong,Z, 2011, The fetal origins of obesity: early origins of altered food intake, Endocrine, Metabolic & Immune Disorders - Drug Targets, 11, 3, 189-197 10.2174/187153011796429835
2010 Morrison,J, Duffield,J, Muhlhausler,B, Gentili,S, McMillen,I, 2010, Fetal growth restriction, catch-up growth and the early origins of insulin resistance and visceral obesity, Pediatric Nephrology, 25, 4, 669-677 10.1007/s00467-009-1407-3
2010 Tu,W, Cook-Johnson,R, James,M, Muhlhausler,B, Gibson,R, 2010, Omega-3 long chain fatty acid synthesis is regulated more by substrate levels than gene expression, Prostaglandins Leukotrienes and Essential Fatty Acids, 83, 2, 61-68 10.1016/j.plefa.2010.04.001
2010 Rattanatray,L, MacLaughlin,S, Kleemann,D, Walker,S, Muhlhausler,B, McMillen,I, 2010, Impact of maternal periconceptional overnutrition on fat mass and expression of adipogenic and lipogenic genes in visceral and subcutaneous fat depots in the postnatal lamb, Endocrinology, 151, 11, 5195-5205 10.1210/en.2010-0501
2010 Muhlhausler,B, Cook-Johnson,R, James,M, Miljkovic,D, Duthoit,E, Gibson,R, 2010, Opposing effects of omega-3 and omega-6 long chain polyunsaturated fatty acids on the expression of lipogenic genes in omental and retroperitoneal adipose depots in the rat, Journal of Nutrition and Metabolism, 2010, 1-9 10.1155/2010/927836
2010 Zhang,S, Rattanatray,L, MacLaughlin,S, Cropley,J, Suter,C, Molloy,L, Kleemann,D, Walker,S, Muhlhausler,B, Morrison,J et al, 2010, Periconceptional undernutrition in normal and overweight ewes leads to increased adrenal growth and epigenetic changes in adrenal IGF2/H19 gene in offspring, FASEB Journal, 24, 8, 2772-2782 10.1096/fj.09-154294
2010 Muhlhausler,B, Gibson,R, Makrides,M, 2010, Effect of long-chain polyunsaturated fatty acid supplementation during pregnancy or lactation on infant and child body composition: a systematic review, American Journal of Clinical Nutrition, 92, 4, 857-863 10.3945/ajcn.2010.29495
2010 Nguyen,L, Muhlhausler,B, Botting,K, Morrison,J, 2010, Maternal undernutrition alters fat cell size distribution, but not lipogenic gene expression, in the visceral fat of the late gestation guinea pig fetus, Placenta, 31, 10, 902-909 10.1016/j.placenta.2010.07.014
2009 Muhlhausler,B, Morrison,J, McMillen,I, 2009, Rosiglitazone increases the expression of peroxisome proliferator-activated receptor-γ target genes in adipose tissue, liver, and skeletal muscle in the sheep fetus in late gestation, Endocrinology, 150, 9, 4287-4294 10.1210/en.2009-0462
2009 Muhlhausler,B, Duffield,J, Ozanne,S, Pilgrim,C, Turner,N, Morrison,J, McMillen,I, 2009, The transition from fetal growth restriction to accelerated postnatal growth: a potential role for insulin signalling in skeletal muscle, Journal of Physiology-London, 587, 17, 4199-4211 10.1113/jphysiol.2009.173161
2009 Duffield,J, Vuocolo,T, Tellam,R, McFarlane,J, Kauter,K, Muhlhausler,B, McMillen,I, 2009, Intrauterine growth restriction and the sex specific programming of leptin and peroxisome proliferator-activated receptor [gamma (PPAR gamma]) mRNA expression in visceral fat in the lamb, Pediatric Research, 66, 1, 59-65 10.1203/PDR.0b013e3181a7c121
2009 Mühlhausler,B, 2009, Nutritional models of type 2 diabetes mellitus., Methods in molecular biology (Clifton, N.J.), 560, 19-36
2009 Muhlhausler,B, Smith,S, 2009, Early-life origins of metabolic dysfunction: role of the adipocyte, Trends in Endocrinology and Metabolism, 20, 2, 51-57 10.1016/j.tem.2008.10.006
2008 Philp,L, Muhlhausler,B, Janovska,A, Wittert,G, Duffield,J, McMillen,I, 2008, Maternal overnutrition suppresses the phosphorylation of 5 '-AMP-activated protein kinase in liver, but not skeletal muscle, in the fetal and neonatal sheep, American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 295, 6, R1982-R1990 10.1152/ajpregu.90492.2008
2008 Duffield,J, Vuocolo,T, Tellam,R, Yuen,B, Muhlhausler,B, McMillen,I, 2008, Placental restriction of fetal growth decreases IGF1 and leptin mRNA expression in the perirenal adipose tissue of late gestation fetal sheep, American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 294, 5, R1413-R1419 10.1152/ajpregu.00787.2007
2008 McMillen,I, MacLaughlin,S, Muhlhausler,B, Gentili,S, Duffield,J, Morrison,J, 2008, Developmental origins of adult health and disease: The role of periconceptional and foetal nutrition, Basic ' Clinical Pharmacology ' Toxicology, 102, 2, 82-89 10.1111/j.1742-7843.2007.00188.x
2008 Muhlhausler,B, Adam,C, McMillen,I, 2008, Maternal nutrition and the programming of obesity: the brain, Organogenesis, 4, 3, 144-152 10.4161/org.4.3.6503
2008 Muhlhausler,B, Ritorto,V, Schultz,C, Chatterton,B, Duffield,J, McMillen,I, 2008, Birth weight and gender determine expression of adipogenic, lipogenic and adipokine genes in perirenal adipose tissue in the young adult sheep, Domestic Animal Endocrinology, 35, 1, 46-57 10.1016/j.domaniend.2008.01.007
2007 Muhlhausler,B, Duffield,J, McMillen,I, 2007, Increased maternal nutrition increases leptin expression in perirenal and subcutaneous adipose tissue in the postnatal lamb, Endocrinology, 148, 12, 6157-6163 10.1210/en.2007-0770
2007 Muhlhausler,B, Adam,C, Findlay,P, Duffield,J, McMillen,I, 2007, Erratum: Increased maternal nutrition alters development of the appetite-regulating network in the brain (FASEB Journal DOI: 10.1096/fj.05-5241fje), FASEB Journal, 21, 2, 629- 10.1096/fj.05-5241err
2007 Muhlhausler,B, Duffield,J, McMillen,I, 2007, Increased maternal nutrition stimulates peroxisome proliferator activated receptor-γ, adiponectin, and leptin messenger ribonucleic acid expression in adipose tissue before birth, Endocrinology, 148, 2, 878-885 10.1210/en.2006-1115
2007 Muhlhausler,B, 2007, Programming of the appetite-regulating neural network: a link between maternal overnutrition and the programming of obesity?, Journal of Neuroendocrinology, 19, 1, 67-72 10.1111/j.1365-2826.2006.01505.x
2007 Duffield,J, Vuocolo,T, Tettam,R, Yuen,B, Muhlhauster,B, McMillen,I, 2007, Placental insufficiency reduces the expression of leptin and IGF1 mRNA in the perirenal adipose tissue of fetal sheep: a mechanism for altered fat development and obesity, EARLY HUMAN DEVELOPMENT, 83, S159-S159 10.1016/S0378-3782(07)70441-3
2006 Muhlhausler,B, Adam,C, Findlay,P, Duffield,J, McMillen,I, 2006, Increased maternal nutrition alters development of the appetite-regulating network in the brain, The FASEB Journal, 20, 8, 1257-1259 10.1096/fj.05-5241fje
2006 McMillen,I, Edwards,L, Duffield,J, Muhlhausler,B, 2006, Regulation of leptin synthesis and secretion before birth: implications for the early programming of adult obesity, Reproduction, 131, 3, 415-427 10.1530/rep.1.00303
2006 MacLaughlin,S, Muhlhausler,B, Gentili,S, McMillen,I, 2006, When in gestation do nutritional alterations exert their effects? A focus on the early origins of adult disease, Current Opinion in Endocrinology, Diabetes and Obesity, 13, 6, 516-522 10.1097/MED.0b013e328010ca30
2005 Muhlhausler,B, Mühlhäusler,P, 2005, Simple English in the South Seas Evangelical Mission: Social context and linguistic attributes, Language Problems and Language Planning, 29, 1, 1-30 10.1075/lplp.29.1.02muh
2005 Muhlhausler,B, Adam,C, Marrocco,E, Findlay,P, Roberts,C, McFarlane,J, Kauter,K, McMillen,I, 2005, Impact of glucose infusion on the structural and functional characteristics of adipose tissue and on hypothalamic gene expression for appetite regulatory neuropeptides in the sheep fetus during late gestation, Journal of Physiology-London, 565, 1, 185-195 10.1113/jphysiol.2004.079079
2005 McMillen,I, Adam,C, Muhlhausler,B, 2005, Early origins of obesity: programming the appetite regulatory system, Journal of Physiology-London, 565, 1, 9-17 10.1113/jphysiol.2004.081992
2004 McMillen,I, Muhlhausler,B, Duffield,J, Yuen,B, 2004, Prenatal programming of postnatal obesity: fetal nutrition and the regulation of leptin synthesis and secretion before birth, Proceedings of the Nutrition Society, 63, 3, 405-412 10.1079/PNS2004370
2004 Muhlhausler,B, McMillen,I, Rouzad,G, Findlay,P, Marrocco,E, Rhind,S, Adam,C, 2004, Appetite regulatory neuropeptides are expressed in the sheep hypothalamus before birth, Journal of Neuroendocrinology, 16, 6, 502-507 10.1111/j.1365-2826.2004.01197.x
2003 Muhlhausler,B, 2003, The "big picture" in obesity research, Science, 300, 5622, 1091-1092 10.1126/science.300.5622.1091d
2003 Yuen,B, Owens,P, Muhlhausler,B, Roberts,C, Symonds,M, Keisler,D, McFarlane,J, Kauter,K, Evens,Y, McMillen,I et al, 2003, Leptin alters the structural and functional characteristics of adipose tissue before birth, FASEB Journal, 17, 6, www 1-www 22 10.1096/fj.02-0756fje
2003 Muhlhausler,B, Roberts,C, Yuen,B, Marrocco,E, Budge,H, Symonds,M, McFarlane,J, Kauter,K, Stagg,P, Pearse,J et al, 2003, Determinants of fetal leptin synthesis, fat mass, and circulating leptin concentrations in well-nourished ewes in late pregnancy, Endocrinology, 144, 11, 4947-4954 10.1210/en.2003-0555
2002 Muhlhausler,B, Roberts,C, McFarlane,J, Kauter,K, McMillen,I, 2002, Fetal leptin is a signal of fat mass independent of maternal nutrition in ewes fed at or above maintenance energy requirements, Biology of Reproduction, 67, 2, 493-499 10.1095/biolreprod67.2.493

Book Chapters

Date Citation
2016 Muhlhausler,BS, Gugusheff,J, 2016, Prenatal programming of the mesolimbic reward pathway and food preferences, Springer, New York, pp. 169-188 10.1007/978-1-4939-3014-2_8
2012 Mühlhäusler,BS, 2012, Roles of Pancreatic Cell Functions, Liver, Skeletal Muscle, and Adipose Tissues in Diabetes and Metabolic Syndrome, pp. 279-288 10.1016/B978-0-12-385083-6.00022-X
2009 McMillen,I, Rattanatray,L, Duffield,J, Morrison,J, MacLaughlin,S, Gentili,S, Muhlhausler,B, 2009, The early originis of later obesity: pathways and mechanisms, Springer, Dordrecht, Netherlands, pp. 71-82 10.1007/978-1-4020-9173-5_8
2009 Mühlhausler,BS, 2009, Nutritional models of type 2 diabetes mellitus, Springer, pp. 19-36 10.1007/978-1-59745-448-3_2
2006 McMillen,I, Duffield,J, Muhlhausler,B, 2006, Prenatal programming of postnatal obesity, Taylor & Francis, United Kingdom, pp. 73-83

Conference Papers

Date Citation
2011 Ong,ZY, Muhlhausler,B, 2011, The Role of mu-Opioid Receptors in the Regulation of Macronutrient Preferences and Body Weight Gain
2011 Vithayathil,MA, Ong,ZY, Muhlhausler,BS, 2011, The Effects of Maternal High Fat Feeding on Body Fat Mass and Susceptibility to Diet Induced Obesity Can Be Reversed by Interventions during the Suckling Period
2011 Ong,ZY, Muhlhausler,BS, 2011, Reversing the Effects of Maternal High-Fat, High-Sugar Feeding on Offspring Food Preferences and Fat Deposition
2011 Gugescheff,J, Morrison,JL, McMillen,CI, Muhlhausler,BS, 2011, Prenatal Activation of PPAR gamma Stimulates NPY Expression in the Fetal Hypothalamus and Promotes Milk Intake in the Lamb
2010 Nicholas,L, Rattanatray,L, McLaughlin,S, Muhlhausler,B, Kleeman,D, Walker,S, Morrison,J, McMillen,C, 2010, Maternal Overnutrition in the Periconceptional Period Results in Altered Expression of Hepatic Metabolic Genes in the Postnatal Lamb, 57th Annual Meeting of the Society-for-Gynecologic-Investigation, Orlando, FL
2010 Rattanatray,L, MacLaughlin,SM, Muhlhausler,BS, Kleemann,D, Walker,S, McMillen,JC, 2010, Periconceptional Overnutrition Results in an Increase in Fat Mass in Female Offspring; the Role of Adipogenic and Lipogenic Genes, 57th Annual Meeting of the Society-for-Gynecologic-Investigation, Orlando, FL
2010 Zhang,S, Rattanatray,L, MacLaughlin,SM, Cropley,JE, Suter,CM, Molloy,L, Kleemann,D, Walker,SK, Muhlhausler,BS, Morrison,JL et al, 2010, Increased Adrenal Growth and Decreased Methylation of the Adrenal Igf2/H19 Differentially Methylated Region after Exposure to Periconceptional Undernutrition., 57th Annual Meeting of the Society-for-Gynecologic-Investigation, Orlando, FL
2010 Nicholas,L, Rattanatray,L, McLaughlin,S, Muhlhausler,B, Kleeman,D, Walker,S, McMillen,C, 2010, Periconceptional Overnutrition and Offspring Gender Influences Hepatic Expression of Metabolic Genes in Postnatal Lamb., 57th Annual Meeting of the Society-for-Gynecologic-Investigation, Orlando, FL
2009 McMillen,C, Duffield,JA, Muhlhausler,BS, Rattanatray,L, Gentili,S, Morrison,JL, 2009, EARLY PATTERNS OF NUTRITION, GROWTH AND METABOLIC HEALTH
2008 Rattanatray,L, Muhlhausler,BS, McMillen,IC, 2008, Maternal overnutrition does not upregulate hepatic 11 beta HSD1 mRNA expression of the fetal and postnatal lamb., 55th Annual Meeting of the Society-for-Gynecologic-Investigation, San Diego, CA
2008 Muhlhausler,B, Duffield,J, Morrison,J, McMillen,I, 2008, Intrauterine growth restriction increases myocellular expression of PGC-1 alpha in male lambs in early postnatal life, 55th Annual Meeting of the Society-for-Gynecologic-Investigation, San Diego, CA
2007 Muhlhausler,B, Duffield,J, Morrison,J, McMillen,I, 2007, Placental restriction and the expression of AMPK in adipose tissue in the late gestation fetal sheep 10.1016/S0378-3782(07)70451-6
2005 Duffield,J, Vuocolo,T, Tellam,R, McFarlane,J, Kauter,K, Muhlhausler,B, McMillen,I, 2005, Differential impact of low birth weight on PPAR gamma and leptin expression in perirenal fat in male and female lambs., 52nd Annual Meeting of the Society-for-Gynecologic-Investigation, Los Angeles, CA
2005 Duffield,J, Tellam,R, Vuocolo,T, McFarlane,J, Kanter,K, Muhlhausler,B, McMillen,I, 2005, Impact of low birth weight and gender on PPAR7, leptin and adiponectin expression in the subcutaneous fat of lambs, Experimental Biology 2005 Meeting/35th International Congress of Physiological Sciences, San Diego, CA
2005 Muhlhausler,B, Duffield,J, McMillen,I, 2005, Maternal overnutrition in late gestation increases peripheral fat deposition in the postnatal lamb, Experimental Biology 2005 Meeting/35th International Congress of Physiological Sciences, San Diego, CA
2005 Muhlhausler,B, Adam,B, Findlay,P, Duffield,J, McMillen,I, 2005, Increased maternal nutrition increases hypothalamic expression of the appetite inhibitor proopiomelanocortin in the postnatal lamb, 3rd International Congress on Developmental Origins of Health and Disease, Toronto, CANADA
2004 Muhlhausler,B, Adam,C, Findlay,P, Marrocco,E, McMillen,I, 2004, Glucose increases the expression of POMC mRNA in the hypothalamus of the fetal sheep in late gestation., 51st Annual Meeting of the Society-for-Gynecologic-Investigation, Houston, TX
2003 Muhlhausler,B, Schultz,C, Chatterton,B, McMillen,I, 2003, Adiposity is positively correlated with weight gain over the first 6 months of postnatal life in female sheep, 2nd World Congress on Dietal Origins of Adult Disease, BRIGHTON, ENGLAND

Conference Items

Date Citation
2017 Gatford,KL, Muhlhausler,BS, Sim,PS-L, Roberts,CT, Veldhuis,JD, Huang,L, Chen,C, 2017, Pulsatile GH profiles in the pregnant mouse reveal marked increases in circulating GH and GH secretion between early and mid-pregnancy
2011 Fong,L, Muhlhausler,B, Gibson,RA, Xian,CJ, 2011, Effects of maternal dietary supplementation of omega-3 fatty acids during pregnancy and lactation on offspring's bone growth and adult bone mass, 3rd Joint Meeting of the European Calcified Tissue Society/International Bone and Mineral Society (ECTS 2011) (IBMS), Athens, Greece 10.1016/j.bone2011.03.376
2009 Muhlhausler,BSCJ, James,M, Duthroit,E, Gibson,RA, 2009, Dietary balance of omega-3 and omega-6 PUFA controls expression of lipogenic genes, 19th International Congress of Nutrition, Bangkok, Thailand 10.1159/000248280

Year

Granting Body

Title

 

Name

Amount

2015

The University of Adelaide DVCR Interdisciplinary Research Fund (IRF)

Consumer perceptions, sensory appeal and nutritional value of edible insects: realising the potential of an emerging agricultural industry.

Wilkinson K, Muhlhausler BS, Ankeny R, Bray H

$25,000

2015-2018

NHMRC Career Development Award (Level 2)

Breaking the Intergenerational Cycle of Obesity through Nutritional Interventions

Muhlhausler BS

$455,113

2015-2016

Diabetes Australia Research Trust

Early Epigenetic Predictors of Insulin Resistance

Muhlhausler BS, Molloy P, VanDijk S, Buckley M, Makrides M

$60,000

2013

Waite Research Institute

How Do Nutrients Regulate the Microbiome-Genome Interactions in the Maturing GI tract of Preterm Infants

Muhlhausler BS, McPhee A, Collins CT, Gibson RA, Makrides M, Penttila , Bianco-Miotto T, Bent S

$70,000

2013-2016

Premier’s Research and Industry Fund

Improving the efficacy of sustainable plant oils to increased omega-3 levels in chicken products

Gibson RA, Hughes B, Hynd P, Muhlhausler B

$150,000

2013-2014

Channel 7 Children’s Health Research Foundation

Low GI diets for improving metabolic outcomes

Muhlhausler B, Brand-Miller J, Gentili S

$70,000

2012-2016

NHMRC Centre of Research Excellence Foods for Future Australians

Foods for Future Australians

Makrides M, Gibson RA, Ryan P, Zhou SJ, Dodd J, McPhee AJ, Umberger W, Muhlhausler B, Collins CT, Penttila I

$2,500,000

2011-2014

SIEF (Science & Industry Endowment Fund)

 

Early Nutrition, the Epigenome and the Prevention of Disease

 

 

Molloy P, Tellam P, Ryan L, Clark S, Samaras K, Cooney GJ, Makrides M, Muhlhausler B, McMillen C, Morrison J, Noakes M.

$2,000,000

2011

NHMRC Equipment Grant

The BOD-POD: A state-of-the-art system for measuring body composition

Couper J, Makrides M, Gibson RA, Dodd J, Muhlhausler BS, Collins CT, McPhee A

$65,000

2011-2014

NHMRC Career Development Award

Better nutrition for mothers and infants for healthier Australians

Muhlhausler B

$384,160

2010-2012

NHMRC Project Grant

Nutrition Before Conception and Later Obesity

McMillen C, Morrison J, Muhlhausler B, Ozanne S

$434,150

2009-2013

NHMRC Project Grant

The Childhood Obesity and Insulin Resistance

 Prevention Study (ChOIR)

Makrides, Muhlhausler, Gibson, McDermott,

Tapsell

$1,380,000

2007-2009

NHMRC Project Grant

The EarlyOrigins

Of Obesity

McMillen IC & Muhlhausler BS

$320,250

2009-2011

Channel 7 Children’s Health Research Foundation

 

Blocking the Early Origins of Obesity: A Role for Omega-3 fatty acids?

Muhlhausler B, Gibson RA

$100,000

2009     

The Clive & Vera Ramaciotti Establishment Grant

Early  Origins of A Taste for Fat: A New Perspective on the Early Life Origins of Obesity

Muhlhausler B

$29,000                    

2009

UniSA Health Sciences Divisional Research Grant

Blocking the Early Origins of Obesity: A Role for Omega-3 fatty acids?

Muhlhausler B

$10,000

2007-2011     

NHMRC Peter Doherty Post Doctoral Fellowship

The Early

Origins of Obesity: A Population Based and Mechanistic Approach

Muhlhausler B

$269,000

2007-2008

Channel 7 Children’s Research Foundation Grant

Intrauterine Growth Restriction and the Early Origins of the Metabolic

Syndrome

Muhlhausler B

$40,000

FOODplus/SAHMRI Healthy Mothers, Babies and Children Theme Students and ECRs August 2016

 

 

 

Current PhD Students

  • Gabriela Esteves Leghi
  • See Meng Lim
  • Chloe Douglas
  • Nina Wilson
  • Khaled Kanakri
  • Erandi Hewawasam
  • Samantha Chown
  • Shannon Hunt
  • Sally Draycott

Past PhD Students

  • Katie Wood (2016)
  • Carla Toop (2016)
  • Dao Huynh (2015)
  • Mini Vithayathil (2015)
  • Jessica Gugusheff (2015)
  • Maryam Bazargan (2015)
  • Liu Ge (2014)

Current Honours Students

  • Jonothan Wurst

 

 

 

Committee Memberships

Date Role Committee Institution Country
2017 President Australia and New Zealand Society for the Developmental Origins of Health and Disease (DOHaD) Australia
2014 Secretary Australia New Zealand Society for the Developmental Origins of Health and Disease Australia
Position
Senior Research Fellow
Phone
83130848
Fax
8313 7135
Campus
Waite
Building
Waite Building
Room Number
GS 20
Org Unit
School of Agriculture, Food and Wine

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