Professor Andrew Abell

Andrew Abell
Professor
School of Physical Sciences
Faculty of Sciences

Andrew graduated from the University of Adelaide with BSc(Hon) and PhD and then undertook a postdoctoral fellowship at the University of Cambridge. He held a professorship at the University of Canterbury before returning to the University of Adelaide in 2007, where he is currently Professor of Chemistry and node director of the ARC Centre of Excellence for Nanoscale Biophotonics. His research interests are concerned with understanding the fundamental link between the chemical structure and shape of key biological molecules and their biological function. While his work is very much driven by fundamental science, he has always had a keen interest in pursuing associated commercial opportunities. The seed for this was sown with a sabbatical leave working as a visiting scientist, consultant and senior Fulbright Fellow with SmithKline Beecham (now GSK) in Philadelphia. In Adelaide he co-founded an Adelaide-based company (Calpain Therapeutics) to develop macrocyclic protease inhibitors as a potential treatment for cataract and other conditions. Past member of ARC College of Experts and Head of School of Chemistry and Physics at the University of Adelaide and also recent recipient of the Royal Australian Chemical Institute Adrien Albert Prize and the Alexander R. Matzuk Prize and Lecture in Drug Discovery (Baylor College of Medicine, Houston).

Connect With Me

Professor Andrew Abell

Andrew graduated from the University of Adelaide with BSc(Hon) and PhD and then undertook a postdoctoral fellowship at the University of Cambridge. He held a professorship at the University of Canterbury before returning to the University of Adelaide in 2007, where he is currently Professor of Chemistry and node director of the ARC Centre of Excellence for Nanoscale Biophotonics. His research interests are concerned with understanding the fundamental link between the chemical structure and shape of key biological molecules and their biological function. While his work is very much driven by fundamental science, he has always had a keen interest in pursuing associated commercial opportunities. The seed for this was sown with a sabbatical leave working as a visiting scientist, consultant and senior Fulbright Fellow with SmithKline Beecham (now GSK) in Philadelphia. In Adelaide he co-founded an Adelaide-based company (Calpain Therapeutics) to develop macrocyclic protease inhibitors as a potential treatment for cataract and other conditions. Past member of ARC College of Experts and Head of School of Chemistry and Physics at the University of Adelaide and also recent recipient of the Royal Australian Chemical Institute Adrien Albert Prize and the Alexander R. Matzuk Prize and Lecture in Drug Discovery (Baylor College of Medicine, Houston).

The focus of our extended group is concerned with the design, synthesis, and exploitation of small molecule enzyme inhibitors and mimics of key biological compounds. These compounds provide a basis of new therapeutics for the treatment of cancer and other diseases, as well as probes to study key metabolic processes such as electron transfer. They can also be attached to surfaces to provide functional materials and biosensors.

Please see our Group webpage: http://physsci.adelaide.edu.au/bomcl/

Please also see the ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP): http://cnbp.org.au/

Please also see Calpain Therapeutics: http://www.calpaintherapeutics.com/

Do you want to join our research group?

PhD Scholarships

University scholarships for Australian students are known as Australian Postgraduate Awards (APA). These scholarships are awarded on the basis of academic merit and in designated areas of research strength within the University. If a student does not secure an APA, then the School of Physical Sciences considers the option of divisional scholarships (based on academic merit and budget limits). The University also offers a range of Scholarships for international students.

Application involves filling in the "application form for admission/scholarship".

When applying for domestic scholarships please remember to tick both the APA and Divisional box.  After the closing date, the Graduate Centre will forward your application to the School to consider. If an APA is not awarded then the school will consider offering a divisional scholarship.  Further details can be found at the scholarship websites http://www.adelaide.edu.au/scholarships/

Further information on international PhD scholarships can be found at:  https://www.adelaide.edu.au/graduatecentre/scholarships/research-international/opportunities/

Postdoctoral Positions

Postdoctoral positions arise from time to time, so if you're interested please get in touch and we'll get back to you ASAP.

Appointments

Date Position Institution name
2014 Adelaide Node Leader Centre for Nanosale BioPhotonics (CNBP)
2013 - 2014 Head of School of Chemistry and Physics The University of Adelaide
2011 Chief Scientific Advisor Calpain Therapeutics
2007 Professor University of Adelaide
2007 Adjunct Professor University of Canterbury
2007 Adjunct Professor Lincoln University (New Zealand)
2001 - 2007 Professor University of Canterbury
1993 - 1994 Visiting Scientist and Fulbright Scientist SmithKline Beecham
1985 - 1987 Postdoctoral Fellow University of Cambridge

Awards and Achievements

Date Type Title Institution Name Amount
2013 Alexander R. Matzuk Prize and Lecture in Drug Discovery
2012 Adrien Albert Prize
2011 The University of Queensland Business School's Enterprize
2010 Adjunct Professor at the University of Canterbury Lincoln University
2007 Adjunct Professor at the University of Canterbury
2007 Fellow of Royal Australian Institute of Chemistry
2004 Elected Member of the New Zealand Centre for Molecular Biodiscovery CoRE
2003 University of Canterbury Erskine Fellowship
2002 Elected member of the New Zealand MacDiarmid Institute for Advanced Materials and Nanotechnology CoRE
2001 University of Canterbury Erskine Fellowship
2000 Elected member of the American Chemical Society
1998 Royal Society of Chemistry Journals Grants for international Authors
1997 Invited Editor for JAI Press, London and Connecticut
1995 Easterfield medal
1995 Fellow of New Zealand Institute of Chemistry (FNZIC)
1993 Fulbright Fellow
1993 12 month visiting scientist SmithKline Beecham Pharmaceuticals USA
1985 George Murray Scholarship
1981 C.S.R. Chemicals Prize

Journals

Date Citation
2017 Yu,J, Horsley,J, Abell,A, 2017, Exploiting the interplay of quantum interference and backbone rigidity on electronic transport in peptides: a step towards bio-inspired quantum interferometers, Molecular Systems Design &​ Engineering, 2, 1, 67-77 10.1039/C6ME00077K
2017 Stubing,DB, Heng,S, Monro,TM, Abell,AD, 2017, A comparative study of the fluorescence and photostability of common photoswitches in microstructured optical fibre, Sensors and Actuators B: Chemical, 239, 474-480 10.1016/j.snb.2016.07.172
2017 Law,C, Sylvia,G, Nemati,M, Yu,J, Losic,D, Abell,A, Santos,A, 2017, Engineering of Surface Chemistry for Enhanced Sensitivity in Nanoporous Interferometric Sensing Platforms, ACS Applied Materials and Interfaces, 9, 10, 8929-8940 10.1021/acsami.7b01116
2017 Pehere,A, Zhang,X, Abell,A, 2017, Macrocyclic Peptidomimetics Prepared by Ring-Closing Metathesis and Azide-Alkyne Cycloaddition, Australian Journal of Chemistry, 70, 2, 138-151 10.1071/CH16532
2016 Greenwood,J, Tan,J, Choong Tzen Ming,J, Abell,A, 2016, Alkalis and skin, Journal of Burn Care and Research, 37, 2, 135-141 10.1097/BCR.0000000000000222
2016 Feng,J, Paparella,A, Booker,G, Polyak,S, Abell,A, 2016, Biotin protein ligase is a target for new antibacterials, Antibiotics, 5, 3, 26-1-26-15 10.3390/antibiotics5030026
2016 Zuber,A, Purdey,M, Schartner,E, Forbes,C, Van Der Hoek,B, Giles,D, Abell,A, Monro,T, Ebendorff-Heidepriem,H, 2016, Detection of gold nanoparticles with different sizes using absorption and fluorescence based method, Sensors and Actuators, B: Chemical, 227, 117-127 10.1016/j.snb.2015.12.044
2016 Feng,J, Paparella,A, Tieu,W, Heim,D, Clark,S, Hayes,A, Booker,G, Polyak,S, Abell,A, 2016, New series of BPL inhibitors to probe the ribose-binding pocket of Staphylococcus aureus biotin protein ligase, ACS Medicinal Chemistry Letters, 7, 12, 1068-1072 10.1021/acsmedchemlett.6b00248
2016 Cottam Jones,J, Harris,P, Scanlon,D, Forbes,B, Brimble,M, Abell,A, 2016, Fluorescent IGF-II analogues for FRET-based investigations into the binding of IGF-II to the IGF-1R, Organic and Biomolecular Chemistry, 14, 9, 2698-2705 10.1039/c5ob02110c
2016 Heng,S, McDevitt,C, Kostecki,R, Morey,J, Eijkelkamp,B, Ebendorff-Heidepriem,H, Monro,T, Abell,A, 2016, Microstructured optical fiber-based biosensors: reversible and nanoliter-scale measurement of zinc ions, ACS Applied Materials and Interfaces, 8, 20, 12727-12732 10.1021/acsami.6b03565
2016 Zhang,X, Adwal,A, Turner,A, Callen,D, Abell,A, 2016, New peptidomimetic boronates for selective inhibition of the chymotrypsin-like activity of the 26S proteasome, ACS Medicinal Chemistry Letters, 7, 12, 1039-1043 10.1021/acsmedchemlett.6b00217
2016 Sutton-McDowall,M, Wu,L, Purdey,M, Abell,A, Goldys,E, MacMillan,K, Thompson,J, Robker,R, 2016, Non-esterified fatty acid-induced endoplasmic reticulum stress in cattle cumulus oocyte complexes alters cell metabolism and developmental competence, Biology of Reproduction, 94, 1, 23 -1-23 -9 10.1095/biolreprod.115.131862
2016 Zhang,X, Bruning,J, George,J, Abell,A, 2016, A mechanistic study on the inhibition of α-chymotrypsin by a macrocyclic peptidomimetic aldehyde, Organic and Biomolecular Chemistry, 14, 29, 6970-6978 10.1039/c6ob01159d
2016 Carpenter,R, Holman,A, Abell,A, Grice,K, 2016, Cretaceous fire in Australia: a review with new geochemical evidence, and relevance to the rise of the angiosperms, Australian Journal of Botany, 64, 8, 564-578 10.1071/BT16109
2016 Keeling,K, Cho,O, Scanlon,D, Booker,G, Abell,A, Wegener,K, 2016, The key position: influence of staple location on constrained peptide conformation and binding, Organic & Biomolecular Chemistry, 14, 41, 9731-9735 10.1039/c6ob01745b
2016 Yu,J, Horsley,JR, Abell,AD, 2016, Turning electron transfer 'on-off' in peptides through side-bridge gating, Electrochimica Acta, 209, 65-74 10.1016/j.electacta.2016.05.067
2016 Stubing,D, Heng,S, Abell,A, 2016, Crowned spiropyran fluoroionophores with a carboxyl moiety for the selective detection of lithium ions, Organic and Biomolecular Chemistry, 14, 15, 3752-3757 10.1039/c6ob00468g
2015 Kumeria,T, Yu,J, Alsawat,M, Kurkuri,MD, Santos,A, Abell,AD, Losic,D, 2015, Membranes: photoswitchable membranes based on Peptide-modified nanoporous anodic alumina: toward smart membranes for on-demand molecular transport (adv. Mater. 19/2015)., Advanced materials (Deerfield Beach, Fla.), 27, 19, 2950- 10.1002/adma.201570127
2015 Purdey,M, Thompson,J, Monro,T, Abell,A, Schartner,E, 2015, A dual sensor for pH and hydrogen peroxide using polymer-coated optical fibre tips, Sensors, 15, 12, 31904-31913 10.3390/s151229893
2015 Kumeria,T, Yu,J, Alsawat,M, Kurkuri,M, Santos,A, Abell,A, Losic,D, 2015, Photoswitchable membranes based on peptide-modified nanoporous anodic alumina: toward smart membranes for on-demand molecular transport, Advanced Materials, 27, 19, 3019-3024 10.1002/adma.201500473
2015 Schartner,EP, Tsiminis,G, François,A, Kostecki,R, Warren-Smith,SC, Nguyen,LV, Heng,S, Reynolds,T, Klantsataya,E, Rowland,KJ et al, 2015, Taming the light in microstructured optical fibers for sensing, International Journal of Applied Glass Science, 6, 3, 229-239 10.1111/ijag.12128
2015 Purdey,M, Connaughton,H, Whiting,S, Schartner,E, Monro,T, Thompson,J, John Aitken,R, Abell,A, 2015, Boronate probes for the detection of hydrogen peroxide release from human spermatozoa, Free Radical Biology & Medicine, 81, 69-76 10.1016/j.freeradbiomed.2015.01.015
2015 Sutton-McDowall,M, Purdey,M, Brown,H, Abell,A, Mottershead,D, Cetica,P, Dalvit,G, Goldys,E, Gilchrist,R, Gardner,D et al, 2015, Redox and anti-oxidant state within cattle oocytes following in vitro maturation with bone morphogenetic protein 15 and follicle stimulating hormone, Molecular Reproduction and Development, 82, 4, 281-294 10.1002/mrd.22470
2015 Tieu,W, Polyak,S, Paparella,A, Yap,M, Soares Da Costa,T, Ng,B, Wang,G, Lumb,R, Bell,J, Turnidge,J et al, 2015, Improved synthesis of biotinol-5'-AMP: implications for antibacterial discovery, ACS Medicinal Chemistry Letters, 6, 2, 216-220 10.1021/ml500475n
2015 Horsley,J, Yu,J, Abell,A, 2015, The correlation of electrochemical measurements and molecular junction conductance simulations in β-strand peptides, Chemistry, 21, 15, 5926-5933 10.1002/chem.201406451
2015 Zhang,X, Heng,S, Abell,A, 2015, Photoregulation of α-chymotrypsin activity by spiropyran-based inhibitors in solution and attached to an optical fiber, Chemistry, 21, 30, 10703-10713 10.1002/chem.201501488
2014 Chua,K, Pietsch,M, Zhang,X, Hautmann,S, Chan,H, Bruning,J, Gütschow,M, Abell,A, 2014, Macrocyclic protease inhibitors with reduced peptide character, Angewandte Chemie International Edition, 53, 30, 7828-7831 10.1002/anie.201404301
2014 Jones,SA, Duncan,J, Aitken,SG, Coxon,JM, Abell,AD, 2014, The preparation of macrocyclic calpain inhibitors by ring closing metathesis and cross metathesis, Australian Journal of Chemistry, 67, 9, 1257-1263 10.1071/CH14121
2014 Paparella,A, Soares Da Costa,T, Yap,M, Tieu,W, Wilce,M, Booker,G, Abell,A, Polyak,S, 2014, Structure guided design of biotin protein ligase inhibitors for antibiotic discovery, Current Topics in Medicinal Chemistry, 14, 1, 4-20 10.2174/1568026613666131111103149
2014 Horsley,J, Yu,J, Moore,K, Shapter,J, Abell,A, 2014, Unraveling the interplay of backbone rigidity and electron rich side-chains on electron transfer in peptides: the realization of tunable molecular wires, Journal of the American Chemical Society, 136, 35, 12479-12488 10.1021/ja507175b
2014 Yu,J, Horsley,J, Moore,K, Shapter,J, Abell,A, 2014, The effect of a macrocyclic constraint on electron transfer in helical peptides: a step towards tunable molecular wires, Chemical Communications, 50, 14, 1652-1654 10.1039/C3CC47885H
2014 Pendini,N, Yap,M, Polyak,S, Cowieson,N, Abell,A, Booker,G, Wallace,J, Wilce,J, Wilce,M, 2014, Erratum: Structural characterisation of Staphylococcus aureus biotin protein ligase and interaction partners: An antibiotic target (Protein Science (2013) 22 (762-773)), Protein Science, 23, 1, 121- 10.1002/pro.2399
2014 Soares da Costa,T, Yap,M, Perugini,M, Wallace,J, Abell,A, Wilce,M, Polyak,S, Booker,G, 2014, Dual roles of F123 in protein homodimerization and inhibitor binding to biotin protein ligase from Staphylococcus aureus, Molecular Microbiology, 91, 1, 110-120 10.1111/mmi.12446
2014 Tieu,W, Jarrad,A, Paparella,A, Keeling,K, Soares da Costa,T, Wallace,J, Booker,G, Polyak,S, Abell,A, 2014, Heterocyclic acyl-phosphate bioisostere-based inhibitors of Staphylococcus aureus biotin protein ligase, Bioorganic & Medicinal Chemistry Letters, 24, 19, 4689-4693 10.1016/j.bmcl.2014.08.030
2014 Heng,S, Mak,A, Stubing,D, Monro,T, Abell,A, 2014, Dual sensor for Cd(II) and Ca(II): selective nanoliter-scale sensing of metal ions, Analytical Chemistry, 86, 7, 3268-3272 10.1021/ac500619z
2013 Tieu,W, Soares da Costa,T, Yap,M, Keeling,K, Wilce,M, Wallace,J, Booker,G, Polyak,S, Abell,A, 2013, Optimising in situ click chemistry: the screening and identification of biotin protein ligase inhibitors, Chemical Science, 4, 9, 3533-3537 10.1039/c3sc51127h
2013 Heng,S, Nguyen,MC, Kostecki,R, Monro,T, Abell,A, 2013, Nanoliter-scale, regenerable ion sensor: sensing with a surface functionalized microstructured optical fibre, RSC Advances, 3, 22, 8308-8317 10.1039/c3ra40321a
2013 Yu,J, Horsley,J, Abell,A, 2013, The influence of secondary structure on electron transfer in peptides, Australian Journal of Chemistry, 66, 8, 848-851 10.1071/CH13276
2013 Pendini,N, Yap,M, Polyak,S, Cowieson,N, Abell,A, Booker,G, Wallace,J, Wilce,J, Wilce,M, 2013, Structural characterization of Staphylococcus aureus biotin protein ligase and interaction partners: An antibiotic target, Protein Science, 22, 6, 762-773 10.1002/pro.2262
2013 Pehere,A, Pietsch,M, Gutschow,M, Neilsen,P, Pedersen,D, Nguyen,S, Zvarec,O, Sykes,M, Callen,D, Abell,A et al, 2013, Synthesis and extended activity of triazole-containing macrocyclic protease inhibitors, Chemistry-A European Journal, 19, 24, 7975-7981 10.1002/chem.201204260
2013 Morton,J, Lee,H, McDermott,J, Robertson,L, Bickerstaffe,R, Jones,M, Coxon,J, Abell,A, 2013, A macrocyclic calpain inhibitor slows the development of inherited cortical cataracts in a sheep model, Investigative Ophthalmology and Visual Science, 54, 1, 389-395 10.1167/iovs.12-11088
2013 Cottam,J, Scanlon,D, Karas,J, Calabrese,A, Pukala,T, Forbes,B, Wallace,J, Abell,A, 2013, Chemical synthesis of a fluorescent IGF-II analogue, International Journal of Peptide Research and Therapeutics, 19, 1, 61-69 10.1007/s10989-012-9339-3
2013 Jones,S, Neilsen,P, Siew,L, Callen,D, Goldfarb,N, Dunn,B, Abell,A, 2013, A template-based approach to inhibitors of calpain 2, 20S proteasome, and HIV-1 protease, ChemMedChem, 8, 12, 1918-1921 10.1002/cmdc.201300387
2013 Neilsen,P, Pehere,A, Pishas,K, Callen,D, Abell,A, 2013, New 26S proteasome inhibitors with high selectivity for chymotrypsin-like activity and p53-dependent cytotoxicity, ACS Chemical Biology, 8, 2, 353-359 10.1021/cb300549d
2013 Li,Y, Coller,J, Hutchinson,M, Klein,K, Zanger,U, Stanley,N, Abell,A, Somogyi,A, 2013, The CYP2B6*6 allele significantly alters the N-demethylation of ketamine enantiomers in vitro, Drug Metabolism and Disposition, 41, 6, 1264-1272 10.1124/dmd.113.051631
2013 Heng,S, McDevitt,C, Stubing,D, Whittall,J, Thompson,J, Engler,T, Abell,A, Monro,T, 2013, Microstructured optical fibers and live cells: a water-soluble, photochromic zinc sensor, Biomacromolecules, 14, 10, 3376-3379 10.1021/bm401040v
2013 Pehere,A, Sumby,C, Abell,A, 2013, New cylindrical peptide assemblies defined by extended parallel β-sheets, Organic & Biomolecular Chemistry, 11, 3, 425-429 10.1039/C2OB26637G
2013 Moore,K, Flavel,B, Yu,J, Abell,A, Shapter,J, 2013, Increased redox-active peptide loading on carbon nanotube electrodes, Electrochimica Acta, 89, 206-211 10.1016/j.electacta.2012.10.108
2012 Chen,H, Jiao,W, Jones,M, Coxon,J, Morton,J, Bickerstaffe,R, Pehere,A, Zvarec,O, Abell,A, 2012, New tripeptide-based macrocyclic calpain inhibitors formed by n-alkylation of histidine, Chemistry & Biodiversity, 9, 11, 2473-2484 10.1002/cbdv.201200320
2012 Yu,J, Zvarec,O, Huang,D, Bissett,M, Scanlon,D, Shapter,J, Abell,A, 2012, Electron transfer through α-peptides attached to vertically aligned carbon nanotube arrays: a mechanistic transition, Chemical Communications, 48, 8, 1132-1134 10.1039/c2cc16665h
2012 Yu,J, Huang,D, Shapter,J, Abell,A, 2012, Electrochemical and computational studies on intramolecular dissociative electron transfer in β‐peptides, Journal of Physical Chemistry C, 116, 50, 26608-26617 10.1021/jp3082563
2012 Polyak,S, Abell,A, Wilce,M, Zhang,L, Booker,G, 2012, Structure, function and selective inhibition of bacterial acetyl-coa carboxylase, Applied Microbiology and Biotechnology, 93, 3, 983-992 10.1007/s00253-011-3796-z
2012 Pehere,A, Abell,A, 2012, New β-strand templates constrained by Huisgen cycloaddition, Organic Letters, 14, 5, 1330-1333 10.1021/ol3002199
2012 Peddie,V, Abell,A, 2012, A study on the diastereoselective synthesis of α-fluorinated β³-amino acids by α-fluorination, Helvetica Chimica Acta, 95, 12, 2460-2473 10.1002/hlca.201200520
2012 Soares da Costa,T, Tieu,W, Yap,M, Pendini,N, Polyak,S, Pedersen,D, Morona,R, Turnidge,J, Wallace,J, Wilce,M et al, 2012, Selective inhibition of biotin protein ligase from Staphylococcus aureus, Journal of Biological Chemistry, 287, 21, 17823-17832 10.1074/jbc.M112.356576
2012 Zvarec,O, Polyak,S, Tieu,W, Kuan,K, Dai,H, Pedersen,D, Morona,R, Zhang,L, Booker,G, Abell,A et al, 2012, 5-Benzylidenerhodanine and 5-benzylidene-2-4-thiazolidinedione based antibacterials, Bioorganic & Medicinal Chemistry Letters, 22, 8, 2720-2722 10.1016/j.bmcl.2012.02.100
2012 Soares da Costa,T, Tieu,W, Yap,M, Zvarec,O, Bell,J, Turnidge,J, Wallace,J, Booker,G, Wilce,M, Abell,A et al, 2012, Biotin analogues with antibacterial activity are potent inhibitors of biotin protein ligase, ACS Medicinal Chemistry Letters, 3, 6, 509-514 10.1021/ml300106p
2012 Peddie,V, Butcher,R, Robinson,W, Wilce,M, Traore,D, Abell,A, 2012, Synthesis and conformation of fluorinated β-peptidic compounds, Chemistry-A European Journal, 18, 21, 6655-6662 10.1002/chem.201200313
2011 Packwood,D, Brooksby,P, Abell,A, Downard,A, 2011, pH-dependent wettability of carboxyphenyl films grafted to glassy carbon, Australian Journal of Chemistry, 64, 1, 122-126 10.1071/CH10285
2011 Lim,S, Neilsen,P, Sharma,R, Abell,A, Callen,D, 2011, The application of delivery systems for DNA methyltransferase inhibitors, Biodrugs, 25, 4, 227-242 10.2165/11592770-000000000-00000
2011 Pehere,A, Abell,A, 2011, Selective N-acylation and N-alkylation of biotin, Journal of Organic Chemistry, 76, 22, 9514-9518 10.1021/jo201615j
2011 Zaman,S, Chen,H, Abell,A, 2011, Studies of a soluble polyethylene glycol immobilized ruthenium catalyst in aqueous media, Tetrahedron Letters, 52, 8, 878-880 10.1016/j.tetlet.2010.12.046
2011 Pehere,A, Abell,A, 2011, An improved large scale procedure for the preparation of N-Cbz amino acids, Tetrahedron Letters, 52, 13, 1493-1494 10.1016/j.tetlet.2011.01.102
2011 Wang,T, Tran,T, Scanlon,D, Andreazza,H, Abell,A, Bowie,J, 2011, Diagnostic di- and triphosphate cyclisation in the negative ion electrospray mass spectra of phosphoSer peptides, Rapid Communications in Mass Spectrometry, 25, 18, 2649-2656 10.1002/rcm.5171
2011 Pedersen,D, Abell,A, 2011, 1,2,3-triazoles in peptidomimetic chemistry, European Journal of Organic Chemistry, 2011, 13, 2399-2411 10.1002/ejoc.201100157
2011 Ellis-Steinborner,S, Scanlon,D, Musgrave,I, Tran,T, Hack,S, Wang,T, Abell,A, Tyler,M, Bowie,J, 2011, An unusual kynurenine-containing opioid tetrapeptide from the skin gland secretion of the Australian red tree frog Litoria rubella. Sequence determination by electrospray mass spectrometry, Rapid Communications in Mass Spectrometry, 25, 12, 1735-1740 10.1002/rcm.5041
2011 Warren-Smith,S, Heng,S, Ebendorff-Heidepriem,H, Abell,A, Monro,T, 2011, Fluorescence-Based Aluminum Ion Sensing using a Surface Functionalized Microstructured Optical Fiber, Langmuir, 27, 9, 5680-5685 10.1021/la2002496
2011 Stuart,B, Coxon,J, Morton,J, Abell,A, McDonald,D, Aitken,S, Jones,M, Bickerstaffe,R, 2011, Molecular modeling: A search for a calpain inhibitor as a new treatment for cataractogenesis, Journal of Medicinal Chemistry, 54, 21, 7503-7522 10.1021/jm200471r
2011 Heng,S, Tieu,W, Hautmann,S, Kuan,K, Pedersen,D, Pietsch,M, Gutschow,M, Abell,A, 2011, New cholesterol esterase inhibitors based on rhodanine and thiazolidinedione scaffolds, Bioorganic & Medicinal Chemistry, 19, 24, 7453-7463 10.1016/j.bmc.2011.10.042
2011 Brooksby,P, Anderson,K, Downard,A, Abell,A, 2011, Voltammetric and electrochemical impedance study of ferrocenyl containing beta-peptide monolayers on gold, The Journal of Physical Chemistry Part C: Nanomaterials and Interfaces, 115, 15, 7516-7526 10.1021/jp112278g
2010 Stanley,N, Hutchinson,M, Kvist,T, Nielsen,B, Mathiesen,J, Brauner-Osborne,H, Avery,T, Tiekink,E, Pedersen,D, Irvine,R et al, 2010, A new metabotropic glutamate receptor agonist with in vivo anti-allodynic activity, Bioorganic & Medicinal Chemistry, 18, 16, 6089-6098 10.1016/j.bmc.2010.06.051
2010 Peddie,V, Pietsch,M, Bromfield,K, Pike,R, Duggan,P, Abell,A, 2010, Fluorinated β²- and β³-amino acids: synthesis and inhibition of α-chymotrypsin, Synthesis-Stuttgart, 2010, 11, 1845-1859 10.1055/s-0029-1218743
2010 Brooksby,P, Anderson,K, Downard,A, Abell,A, 2010, Electrochemistry of ferrocenoyl β-peptide monolayers on gold, Langmuir, 26, 2, 1334-1339 10.1021/la902402t
2010 Stanley,N, Pedersen,D, Nielsen,B, Kvist,T, Mathiesen,J, Brauner-Osborne,H, Taylor,D, Abell,A, 2010, 1,2,3-Triazolyl amino acids as AMPA receptor ligands, Bioorganic & Medicinal Chemistry Letters, 20, 24, 7512-7515 10.1016/j.bmcl.2010.09.139
2010 Pearson,D, Abell,A, 2010, Structural optimization of photoswitch ligands for surface attachment of α-chymotrypsin and regulation of its surface binding, Chemistry-A European Journal, 16, 23, 6983-6992 10.1002/chem.200903369
2010 Ballet,S, Marczak,E, Feytens,D, Salvadori,S, Sasaki,Y, Abell,A, Lazarus,L, Balboni,G, Tourwe,D, 2010, Novel multiple opioid ligands based on 4-aminobenzazepinone (Aba), azepinoindole (Aia) and tetrahydroisoquinoline (Tic) scaffolds, Bioorganic & Medicinal Chemistry Letters, 20, 5, 1610-1613 10.1016/j.bmcl.2010.01.055
2010 Pietsch,M, Chua,K, Abell,A, 2010, Calpains: Attractive targets for the development of synthetic inhibitors, Current Topics in Medicinal Chemistry, 10, 3, 270-293 10.2174/156802610790725489
2009 Zaman,S, Curnow,O, Abell,A, 2009, Development of Aqueous Metathesis Catalysts, Australian Journal of Chemistry, 62, 2, 91-100 10.1071/CH08470
2009 Abell,A, Jones,M, Coxon,J, Morton,J, Aitken,S, McNabb,S, Lee,H, Mehrtens,J, Alexander,N, Stuart,B et al, 2009, Molecular modeling, synthesis, and biological evaluation of macrocyclic calpain inhibitors, Angewandte Chemie-International Edition, 48, 8, 1455-1458 10.1002/anie.200805014
2009 Jones,S, Jones,M, McNabb,S, Aitken,S, Coxon,J, Abell,A, 2009, N-heterocyclic dipeptide aldehyde calpain inhibitors, Protein and Peptide Letters, 16, 12, 1466-1472 10.2174/092986609789839296
2009 Jones,M, Coxon,J, McNabb,S, Mehrtens,J, Alexander,N, Jones,S, Chen,H, Buisan,C, Abell,A, 2009, Efficient Large-Scale Synthesis of CAT811, a Potent Calpain Inhibitor of Interest in the Treatment of Cataracts, Australian Journal of Chemistry, 62, 7, 671-675 10.1071/CH09101
2009 Zaman,S, Abell,A, 2009, A robust and recyclable ruthenium catalyst immobilised on polyethylene glycol, Tetrahedron Letters, 50, 38, 5340-5343 10.1016/j.tetlet.2009.07.022
2009 Abell,A, Alexander,N, Aitken,S, Chen,H, Coxon,J, Jones,M, McNabb,S, Muscroft-Taylor,A, 2009, Synthesis of macrocyclic β-Strand memplates by ring closing metathesis, Journal of Organic Chemistry, 74, 11, 4354-4356 10.1021/jo802723w
2009 Ebert,MO, Gardiner,J, Ballet,S, Abell,A, Seebach,D, 2009, Synthesis and high-resolution NMR structure of a β³-octapeptide with and without a tether introduced by olefin metathesis, Helvetica Chimica Acta, 92, 12, 2643-2658 10.1002/hlca.200900311
2008 Lee,H, Morton,J, Robertson,L, McDermott,J, Bickerstaffe,R, Abell,A, Jones,M, Mehrtens,J, Coxon,J, 2008, Evaluation of a novel calpain inhibitor as a treatment for cataract, Clinical and Experimental Ophthalmology, 36, 9, 852-860 10.1111/j.1442-9071.2009.01925.x
2008 Pearson,D, Abell,A, 2008, D-Leu-L-Phe-containing dipeptide inhibitors of -chymosrypsin- the role of the N- and C-termini in enzyme affinity, ARKIVOC, 2008, 12, 85-93
2008 Ballet,S, Pietsch,M, Abell,A, 2008, Multiple ligands in opioid research, Protein and Peptide Letters, 15, 7, 668-682 10.2174/092986608785133672
2008 Brooksby,P, Schiel,D, Abell,A, 2008, Electrochemistry of catechol terminated monolayers with Cu(II), Ni(II) and, Fe(III) cations: A model for the marine adhesive interface, Langmuir, 24, 16, 9074-9081 10.1021/la8007816
2008 Jones,M, Morton,J, Coxon,J, McNabb,S, Lee,H, Aitken,S, Mehrtens,J, Robertson,L, Neffe,A, Miyamoto,S et al, 2008, Synthesis, biological evaluation and molecular modelling of N-heterocyclic dipeptide aldehydes as selective calpain inhibitors, Bioorganic & Medicinal Chemistry, 16, 14, 6911-6923 10.1016/j.bmc.2008.05.048
2008 Pearson,D, Alexander,N, Abell,A, 2008, Improved photocontrol of alpha-chymotrypsin activity: Peptidomimetic trifluoromethylketone photoswitch enzyme inhibitors, Chemistry-A European Journal, 14, 24, 7358-7365 10.1002/chem.200800082
2008 Vernall,A, Ballet,S, Abell,A, 2008, Cross-metathesis and ring-closing metathesis reactions of amino acid-based substrates, Tetrahedron, 64, 18, 3980-3997 10.1016/j.tet.2008.02.043
2008 Edmonds,M, Graichen,F, Gardiner,J, Abell,A, 2008, Enantioselective synthesis of α-fluorinated β²-amino acids, Organic Letters, 10, 5, 885-887 10.1021/ol703045z
2007 Zaman,S, Kitamura,M, Abell,A, 2007, Synthesis of 5-phenyl 2-functionalized pyrroles by amino Heck and Tandem amino Heck carbonylation reactions, Australian Journal of Chemistry, 60, 8, 624-626 10.1071/CH07132
2007 Abell,A, Jones,M, Neffe,A, Aitken,S, Cain,T, Payne,R, McNabb,S, Coxon,J, Stuart,B, Pearson,D et al, 2007, Investigation into the P3 binding domain of m-calpain using photoswitchable diazo- and triazene-dipeptide aldehydes: New anticataract agents, Journal of Medicinal Chemistry, 50, 12, 2916-2920 10.1021/jm061455n
2007 Mathad,R, Jaun,B, Flogel,O, Gardiner,J, Loweneck,M, Codee,J, Seeberger,P, Seebach,D, Edmonds,M, Graichen,F et al, 2007, NMR-solution structures of fluoro-substituted β-peptides: A 3 14-helix and a hairpin turn. The first case of a 90° O=C-C-F dihedral angle in an a-fluoro-amide group, Helvetica Chimica Acta, 90, 12, 2251-2273 10.1002/hlca.200790235
2007 Paulik,M, Brooksby,P, Abell,A, Downard,A, 2007, Grafting aryl diazonium cations to polycrystalline gold: Insights into film structure using gold oxide reduction redox probe electrochemistry and contact angle behavior, The Journal of Physical Chemistry Part C: Nanomaterials and Interfaces, 111, 21, 7808-7815 10.1021/jp0706578
2007 Payne,R, Peyrot,F, Kerbarh,O, Abell,A, Abell,C, 2007, Rational Design, Synthesis, and Evaluation of Nanomolar Type II Dehydroquinase Inhibitors, ChemMedChem, 2, 7, 1015-1029 10.1002/cmdc.200700032
2007 McCarthy,A, Hartmann,R, Abell,A, 2007, Evaluation of 4'-substituted bicyclic pyridones as non-steroidal inhibitors of steroid 5a-reductase, Bioorganic & Medicinal Chemistry Letters, 17, 13, 3603-3607 10.1016/j.bmcl.2007.04.049
2007 Pearson,D, Downard,A, Muscroft-Taylor,A, Abell,A, 2007, Reversible photoregulation of binding of α-chymotrypsin to a gold surface, Journal of the American Chemical Society, 129, 48, 14862-14863 10.1021/ja0766674
2007 Payne,R, Riboldi-Tunnicliffe,A, Kerbarh,O, Abell,A, Lapthorn,A, Abell,C, 2007, Design, Synthesis, and Structural Studies on Potent Biaryl Inhibitors of Type II Dehydroquinases, ChemMedChem, 2, 7, 1010-1013 10.1002/cmdc.200700062
2006 McCarthy,A, Thomson,B, Shaw,I, Abell,A, 2006, Estrogenicity of pyrethroid insecticide metabolites, Journal of Environmental Monitoring, 8, 1, 197-202 10.1039/b511209e
2006 Pearson,DS, Alexander,NA, Abell,AD, 2006, Light controlled switching of protease inhibition by peptidomimetics, JOURNAL OF PEPTIDE SCIENCE, 12, 167-167
2006 Abell,A, Harvey,A, 2006, Synthesis of a [1,4]dioxane-2,5-dione based-peptidomimetic scaffold, ARKIVOC, 2006, 3, 72-76
2006 Gardiner,J, Aitken,S, McNabb,S, Zaman,S, Abell,A, 2006, Ring closing metathesis of α- and β- amino acid derived dienes, Journal of Organometallic Chemistry, 691, 24-25, 5487-5496 10.1016/j.jorganchem.2006.09.061
2006 Zaman,S, Campaner,P, Abell,A, 2006, Synthesis of amino acid derived seven-membered lactams by RCM and their evaluation against HIV protease, Bioorganic & Medicinal Chemistry, 14, 24, 8323-8331 10.1016/j.bmc.2006.09.009
2006 Brooksby,P, Anderson,K, Downard,A, Abell,A, 2006, Olefin Cross-Metathesis of Vinyl-Terminated Self-Assembled Monolayer (SAM) on Au(111): Electrochemical Study Using a Ferrocenyl Redox Center, Langmuir, 22, 22, 9304-9312 10.1021/la062244o
2006 Pearson,D, Abell,A, 2006, Photoswitch inhibitors of α-chymotrypsin-increased substitution and peptidic character in peptidomimetic boronate esters, Organic & Biomolecular Chemistry, 4, 19, 3618-3625 10.1039/b609320p
2005 ABELL,A, 2005, Design, Synthesis and Evaluation of Peptidomimetic Inhibitors of Proteases, Peptide science : proceedings of the ... Japanese Peptide Symposium, 2004, 63-66
2005 Aitken,S, Abell,A, 2005, Olefin metathesis: Catalyst development, microwave catalysis, and domino applications, Australian Journal of Chemistry, 58, 1, 3-13 10.1071/CH04153
2005 Graichen,F, Giles,K, Abell,A, Garrill,A, 2005, Removal of the nitro and phenyl groups from NPPB decreases its inhibitory effect on cytoplasmic streaming in the alga Nitella hookeri, Biochemistry and Cell Biology-Biochimie et Biologie Cellulaire, 83, 2, 133-139 10.1139/O05-019
2005 Payne,R, Toscano,M, Bulloch,E, Aoell,A, Abell,C, 2005, Design and synthesis of aromatic inhibitors of anthranilate synthase, Organic and Biomolecular Chemistry, 3, 12, 2271-2281 10.1039/b503802b
2005 Neffe,A, Abell,A, 2005, Developments in the design and synthesis of calpain inhibitors, Current Opinion in Drug Discovery & Development, 8, 6, 684-700
2005 Abell,A, Brown,K, Coxon,J, Jones,M, Miyamoto,S, Neffe,A, Nikkel,J, Stuart,B, 2005, Synthesis and evaluation of eight-membered cyclic pseudo-dipeptides, Peptides, 26, 2, 251-258 10.1016/j.peptides.2004.09.006
2005 Zaman,S, Mitsuru,K, Abell,A, 2005, Synthesis of Trisubstituted Imidazoles by Palladium-Catalyzed Cyclization of O-Pentafluorobenzoylamidoximes: Application to Amino Acid Mimetics with a C-Terminal Imidazole, Organic Letters, 7, 4, 609-611 10.1021/ol047628p
2005 Payne,R, Bulloch,E, Abell,A, Abell,C, 2005, Design and synthesis of aromatic inhibitors of anthranilate synthase, Organic & Biomolecular Chemistry, 3, 20, 3629-3635 10.1039/b510633h
2005 Payne,R, Kerbarh,O, Miguel,R, Abell,A, Abell,C, 2005, Inhibition studies on salicylate synthase, Organic & Biomolecular Chemistry, 3, 10, 1825-1827 10.1039/b503800f
2004 Martyn,D, Abell,A, 2004, The Synthesis and Testing of α-(Hydroxymethyl) pyrroles as DNA Binding Agents, Australian Journal of Chemistry, 57, 11, 1073-1077 10.1071/CH04183
2004 Le Sann,C, Abell,A, 2004, Synthesis and Properties of a Mesylated ArgoGel Resin, Australian Journal of Chemistry, 57, 4, 355-358 10.1071/CH03247
2004 Abell,AD, 2004, Chemistry at the interface, AUSTRALIAN JOURNAL OF CHEMISTRY, 57, 9, 819-819 10.1071/CH04180
2004 Gardiner,J, Abell,A, 2004, Synthesis and X-ray structure of functionalised proline mimics, Arkivoc (Online Ed), 2004, 10, 46-52 10.3998/ark.5550190.0005.a06
2004 Vernall,A, Abell,A, 2004, Cross-metathesis coupling of sugars and fatty acids to lysine and cysteine, Organic & Biomolecular Chemistry, 2, 18, 2555-2557 10.1039/b411770k
2004 Gardiner,J, Anderson,K, Downard,A, Abell,A, 2004, The synthesis of cyclic β-amino acid esters from Methionone, Allylglycine, and Serine, Journal of Organic Chemistry, 69, 10, 3375-3382 10.1021/jo049794g
2004 Abell,AD, Vernall,AJ, 2004, CROSS-METATHESIS REACTIONS OF AMINO ACID-DERIVED COMPOUNDS, JOURNAL OF PEPTIDE SCIENCE, 10, 137-137
2004 Gardiner,J, Abell,A, 2004, Synthesis and solid state conformation of phenylalanine mimetics constrained in a proline-like conformation, Organic & Biomolecular Chemistry, 2, 16, 2365-2370 10.1039/B406450J
2004 Daines,A, Abell,A, 2004, The preparation of side chain functionalized analogues of coenzyme Q for protein conjugation studies, Organic & Biomolecular Chemistry, 2, 16, 2371-2375 10.1039/b407659a
2004 Payne,R, Daines,A, Clark,B, Abell,A, 2004, Synthesis and protein conjugation studies of vitamin K analogues, Bioorganic & Medicinal Chemistry, 12, 22, 5785-5791 10.1016/j.bmc.2004.08.037
2004 Le Sann,C, Gower,M, Abell,A, 2004, Inhibitors of types I and II dehydroquinase, Mini - Reviews in Medicinal Chemistry, 4, 7, 747-756
2004 Payne,R, Brown,K, Coxon,J, Morton,J, Lee,H, Abell,A, 2004, Peptidic aldehydes based on α- and β-amino acids: synthesis, inhibition of m-calpain, and anti-cataract properties, Australian Journal of Chemistry, 57, 9, 877-884 10.1071/CH04080
2004 Anderson,KH, Gardiner,J, Abell,AD, 2004, FUNCTIONALISED beta-AMINO ACIDS, JOURNAL OF PEPTIDE SCIENCE, 10, 160-160
2003 Vernall,A, Abell,A, 2003, Cross metathesis of nitrogen-containing systems, Aldrichimica Acta, 36, 3, 93-105 10.1002/chin.200450254
2003 Gardiner,J, Abell,A, 2003, A diastereoselective synthesis of the tetrahydropyridazinone core of 2-oxo-1,6-diazobicyclo[4.3.0]nonane-9-carboxylate-based peptidomimetics starting from (S)-phenylalanine, Tetrahedron Letters, 44, 22, 4227-4230 10.1016/S0040-4039(03)00882-7
2003 Martyn,D, Vernall,A, Clark,B, Abell,A, 2003, Ring-deactivated hydroxyalkylpyrrole-based inhibitors of alpha-chymotrypsin: synthesis and mechanism of action, Organic & Biomolecular Chemistry, 1, 12, 2103-2110 10.1039/b302411c
2003 Humphries,M, Murphy,J, Phillips,A, Abell,A, 2003, Synthesis of functionalized piperidinones, Journal of Organic Chemistry, 68, 6, 2432-2436 10.1021/jo0267091
2003 Le Sann,C, Abell,C, Abell,A, 2003, A Convenient Method for the Synthesis of Dehydroquinic Acid, Synthetic Communications, 33, 4, 527-533 10.1081/SCC-120015805
2003 Giles,K, Humphries,M, Abell,A, Garrill,A, 2003, The synthesis of NPPB and NPBB by reductive amination and the effects of these compounds on K⁺ channels of the alga Nitella hookeri, Bioorganic & Medicinal Chemistry Letters, 13, 2, 293-295 10.1016/S0960-894X(02)00920-4
2003 Daines,A, Payne,R, Humphries,M, Abell,A, 2003, The synthesis of naturally occurring vitamin K and vitamin K analogues, Current Organic Chemistry, 7, 16, 1625-1634 10.2174/1385272033486279
2002 May,B, Abell,A, 2002, α-Methylene tetrazole-based peptidomimetics: synthesis and inhibition of HIV protease, Journal of the Chemical Society. Perkin Transactions 1, 2, 2, 172-178 10.1039/b109128j
2002 Abell,A, Gardiner,J, 2002, Synthesis of substituted cyclohexenyl-based beta-amino acids by ring-closing metathesis, Organic Letters, 4, 21, 3663-3666 10.1021/ol0266121
2002 Payne,R, Abell,A, 2002, Protein binding studies of vitamin K analogues for use in an immunological assay, Chemistry in New Zealand, 66, 1, 16-20
2002 Le Sann,C, Abell,C, Abell,A, 2002, A simple method for the preparation of 3-hydroxyiminodehydroquinate, a potent inhibitor of type II dehydroquinase, Journal of the Chemical Society. Perkin Transactions 1, 18, 18, 2065-2068 10.1039/b206066c
2002 Abell,A, Martyn,D, May,B, Nabbs,B, 2002, An amino acid N-derivatising group that can be coloured on demand, Tetrahedron Letters, 43, 20, 3673-3675 10.1016/S0040-4039(02)00625-1
2001 Abell,A, Nabbs,B, 2001, Ring-deactivated hydroxymethylpyrroles as inhibitors of α-chymotrypsin, Bioorganic & Medicinal Chemistry, 9, 3, 621-628 10.1016/S0968-0896(00)00274-1
2001 Harvey,A, Abell,A, 2001, Alpha-ketoester-based photobiological switches: synthesis, peptide chain extension and assay against alpha-chymotrypsin., Bioorganic & medicinal chemistry letters, 11, 18, 2441-2444 10.1016/s0960-894x(01)00464-4
2001 May,B, Abell,A, 2001, The synthesis and crystal structure of alpha-keto tetrazole-based dipeptide mimics, Tetrahedron Letters, 42, 33, 5641-5644 10.1016/S0040-4039(01)01101-7
2001 Abell,A, Gower,M, 2001, New Herbicidal and Antimicrobial Agents that Inhibit the Shikimate Pathway, New Zealand Science Review, 58, 3, 87-90
2001 Edmonds,M, Abell,A, 2001, Design and synthesis of a conformationally restricted trans peptide isostere based on the bioactive conformations of saquinavir and nelfinavir, Journal of Organic Chemistry, 66, 11, 3747-3752 10.1021/jo0016834
2001 May,B, Abell,A, 2001, The synthesis and solid state structure of (8S)-8-benzyl-8,9-dihydro-7H-tetrazolo[1,5-d][1,4]diazepin-6-one, Chemical Communications, 20, 20, 2080-2081 10.1039/b106175p
2001 Abell,A, 2001, Heterocyclic-based peptidomimetics, Letters in Peptide Science, 8, 3-5, 267-272 10.1023/A:1016216828677
2001 Zubarev,V, Trifonov,R, Filichev,V, Ostrovskii,V, Abell,A, Edmonds,M, 2001, Synthesis, X-ray and conformational studies of novel tetrazole-containing macrocyles: 4,13-dioxa-1,7,8,9,17,18,19,20-octaazatricyclo[14.2.1⁷, ¹⁰]icosa-8,10(20),16(19),17-tetraene and 4,14-dioxa-1,7,8,9,10,18,19,20-octaazatricyclo[15.2.1.0⁷, ¹⁰]icosa-8, Journal of the Chemical Society. Perkin Transactions 2, 3, 3, 417-421 10.1039/b006217k
2001 Harvey,A, Abell,A, 2001, α-Ketoester-based photobiological switches: synthesis, peptide chain extension and assay against α-chymotrypsin, Bioorganic & Medicinal Chemistry Letters, 11, 18, 2441-2444 10.1016/S0960-894X(01)00464-4
2001 Martyn,D, Hoult,D, Abell,A, 2001, Stereocontrol of the Horner-Wadsworth-Emmons Reaction: Application to the Synthesis of HIV-1 Protease Inhibitors, Australian Journal of Chemistry, 54, 6, 391-396 10.1071/CH01093
2000 Phillips,AJ, Morris,JC, Abell,AD, 2000, Progress towards an intramolecular Diels-Alder ring-expansion approach to taxinine: The interplay of Lewis acids and high pressure, Tetrahedron Letters, 41, 15, 2723-2727 10.1016/S0040-4039(00)00248-3
2000 Gerrard,J, Prince,M, Abell,A, 2000, Kinetic characterisation of ene-diol-based inhibitors of α-amylase, Bioorganic and Medicinal Chemistry Letters, 10, 14, 1575-1576 10.1016/S0960-894X(00)00288-2
2000 Abell,A, Prince,M, McNulty,A, Neubauer,B, 2000, Simple Bi- and tricyclic inhibitors of human steroid 5α-Reductase, Bioorganic and Medicinal Chemistry Letters, 10, 17, 1909-1911 10.1016/S0960-894X(00)00368-1
1999 Abell,AD, Nabbs,BK, 1999, Properties and reactions of ring-deactivated deuterated hydroxymethylpyrroles, Organic Letters, 1, 9, 1403-1405 10.1021/ol990959v
1999 May,BCH, Abell,AD, 1999, A convenient preparation of (2SR,3S)-3-amino-2-hydroxy-4-phenylbutanoic acid; an important peptide bond isostere, Synthetic Communications, 29, 14, 2515-2525 10.1080/00397919908086259
1999 Abell,A, Nabbs,B, Battersby,A, Thompson,A, Dolphin,D, 1999, Synthesis and properties of ring-deactivated Deuterated (hydroxymethyl)pyrroles, Chemtracts, 12, 7, 534-538
1999 Abell,AD, Oldham,MD, Moore,MM, Robinson,WT, 1999, The synthesis and X-ray crystal structure of phenylalanine-based N-benzyloxysuccinimides, Australian Journal of Chemistry, 52, 10, 977-981 10.1071/CH99055
1999 Abell,A, Oldham,M, 1999, Leucine-phenylalanine dipeptide-based N-mesyloxysuccinimides: Synthesis of all four stereoisomers and their assay against serine proteases, Bioorganic and Medicinal Chemistry Letters, 9, 3, 497-500 10.1016/S0960-894X(99)00017-7
1999 Martyn,D, Moore,M, Abell,A, 1999, Succinimide and saccharin-based enzyme-activated inhibitors of serine proteases, Current Pharmaceutical Design, 5, 6, 405-415
1999 Nabbs,B, Abell,A, 1999, The synthesis and P388 cytotoxicity of mycalazol 11 and related 5-acyl- 2-hydroxymethylpyrroles, Bioorganic and Medicinal Chemistry Letters, 9, 3, 505-508 10.1016/S0960-894X(99)00021-9
1999 Abell,AD, Gardiner,J, 1999, Synthesis of lactam-based peptidomimetics from β-keto esters and β- keto amides, Journal of Organic Chemistry, 64, 26, 9668-9672 10.1021/jo991306v
1999 Phillips,AJ, Abell,AD, 1999, Ring-closing metathesis of nitrogen-containing compounds: Applications to heterocycles, alkaloids, and peptidomimetics, Aldrichimica Acta, 32, 3, 75-88
1998 Abell,AD, Nabbs,BK, Battersby,AR, 1998, Synthesis and properties of ring-deactivated deuterated (hydroxymethyl)pyrroles, Journal of the American Chemical Society, 120, 8, 1741-1746 10.1021/ja973656+
1998 Abell,AD, Litten,JC, Nabbs,BK, 1998, H-1 NMR study of the hydrolysis of N-acylhydroxy[H-2]methylpyrroles, CHEMICAL COMMUNICATIONS, 8, 919-920 10.1039/a801276h
1998 Abell,AD, Litten,JC, Nabbs,BK, 1998, 1H NMR study of the hydrolysis of N-acylhydroxy[2H]methylpyrroles, Chemical Communications, 8, 919-920 10.1039/a801276h
1998 Abell,AD, Nabbs,BK, Battersby,AR, 1998, The reaction of N-magnesium derivatives of pyrroles with N- mesylchloromethylpyrroles: A synthesis of dipyrrylmethanes, Journal of Organic Chemistry, 63, 23, 8163-8169 10.1021/jo980573i
1998 Abell,AD, Phillips,AJ, Budhia,S, McNulty,AM, Neubauer,BL, 1998, The preparation and biological activity of lactam-based, non-steroidal, inhibitors of human type-1 steroid 5α-reductase, Australian Journal of Chemistry, 51, 5, 389-396 10.1071/C97130
1998 Abell,A, Ratcliffe,M, Gerrard,J, 1998, Ascorbic acid-based inhibitors of α-amylases, Bioorganic and Medicinal Chemistry Letters, 8, 13, 1703-1706 10.1016/S0960-894X(98)00298-4
1998 Abell,AD, Gardiner,J, Phillips,AJ, Robinson,WT, 1998, Synthesis and X-ray structure of a 1,2,3,6-tetrahydropyridine-based phenylalanine mimetic, Tetrahedron Letters, 39, 51, 9563-9566 10.1016/S0040-4039(98)02125-X
1997 Abell,AD, Brandt,M, Levy,MA, Holt,DA, 1997, Preparation and biological activity of tricyclic non-steroidal inhibitors of human steroid 5α-reductase, Journal of the Chemical Society - Perkin Transactions 1, 11, 1663-1667 10.1039/a608169j
1997 Abell,AD, Hoult,DA, Bergman,DA, Fairlie,DP, 1997, Simple cis-epoxide-based inhibitors of HIV-1 protease, Bioorganic and Medicinal Chemistry Letters, 7, 22, 2853-2856 10.1016/S0960-894X(97)10106-8
1997 Abell,AD, Edwards,RA, Oldham,MD, 1997, Chemistry and X-ray crystallographic structure of N-protected (5-oxo-1,3-oxazolidin-4-yl)acetic acids: Versatile intermediates in the synthesis of peptidomimetics, Journal of the Chemical Society - Perkin Transactions 1, 11, 1655-1662 10.1039/a608165g
1997 Abell,AD, Blunt,JW, Foulds,GJ, Munro,MHG, 1997, Chemistry of the mycalamides: Antiviral and antitumour compounds from a New Zealand marine sponge. Part 6. The synthesis and testing of analogues of the C(7)-C(10) fragment, Journal of the Chemical Society - Perkin Transactions 1, 11, 1647-1654 10.1039/a608168a
1997 Carr,A, Winterbourn,C, Blunt,J, Phillips,A, Abell,A, 1997, Nuclear magnetic resonance characterization of 6α-chloro-5β- cholestane-3β,5-diol formed from the reaction of hypochlorous acid with cholesterol, Lipids, 32, 4, 363-367 10.1007/s11745-997-0046-8
1997 Abell,AD, Foulds,GJ, 1997, Synthesis of a cis-conformationally restricted peptide bond isostere and its application to the inhibition of the HIV-1 protease, Journal of the Chemical Society - Perkin Transactions 1, 17, 2475-2482 10.1039/a702458d
1997 Abell,AD, Oldham,MD, 1997, Synthesis and X-ray crystallographic structure of leucine-phenylalanyl succinimide-based pseudopeptides, Journal of Organic Chemistry, 62, 5, 1509-1513 10.1021/jo961781i
1996 Abell,AD, Brandt,M, Levy,MA, Holt,DA, 1996, The preparation and evaluation of (+/-)-trans-1-diazo-8-methoxy-4a-methyl-1,2,3,4,4a,9,10,10a-octahydro- phenanthren-2-one as an inhibitor of human type-1 steroid 5α-reductase, Bioorganic and Medicinal Chemistry Letters, 6, 7, 883-884 10.1016/0960-894X(96)00136-9
1996 Abell,AD, Taylor,JM, Oldham,MD, 1996, Self-addition products from the alkylation of amino acid-derived oxazolidinones: X-ray molecular structures of (2R,4S,1′S)-3-benzoyl-4-[benzoylamino(phenyl)methyl]-4-benzyl-2-phenyl-1, 3-oxazolidin-5-one, (2R,4S,1′S)- and (2R,4S,1′R)-3-benzoyl-4-[benzoylamino(phenyl)methyl]-4-isopropyl-2-phenyl- 1,3-oxazolidin-5-one, Journal of the Chemical Society - Perkin Transactions 1, 11, 1299-1304 10.1039/p19960001299
1996 Abell,AD, Brandt,M, Levy,MA, Holt,DA, 1996, A comparison of steroidal and non-steroidal inhibitors of human steroid 5α-reductase: New tricyclic aryl acid inhibitors of the type-1 isozyme, Bioorganic and Medicinal Chemistry Letters, 6, 4, 481-484 10.1016/0960-894X(96)00054-6
1995 Holt,D, Yamashita,D, Konialian-Beck,A, Luengo,J, Abell,A, Bergsma,D, Brandt,M, Levy,M, 1995, Benzophenone- and indolecarboxylic acids: Potent type-2 specific inhibitors of human steroid 5α-reductase, Journal of Medicinal Chemistry, 38, 1, 13-15 10.1021/jm00001a004
1995 Abell,AD, Henderson,BR, 1995, Steroidal and non-steroidal inhibitors of steroid 5α-reductase, Current Medicinal Chemistry, 2, 1, 583-597
1995 Abell,AD, Oldham,MD, Taylor,JM, 1995, Synthesis of phenylalanine-based cyclic acylated enamino ester dipeptide analogues: Inhibitors of α-chymotrypsin. X-ray molecular structure of (2′S,4′R)-4′-benzyl-3′-benzyloxycarbonyl-5′-oxo- 2′-phenyloxazolidin-4′-ylacetic acid, Journal of the Chemical Society, Perkin Transactions 1, 7, 953-961 10.1039/p19950000953
1995 Abell,AD, Oldham,MD, Taylor,JM, 1995, Synthesis of cyclic acylated enamino esters from enol lactones, 4-keto amides, and 5-hydroxy lactams, Journal of Organic Chemistry, 60, 5, 1214-1220 10.1021/jo00110a026
1994 Abell,AD, Brandt,M, Levy,MA, Holt,DA, 1994, A non-steroidal diene acid inhibitor of human type 2 stereoid 5α-reductase, Bioorganic and Medicinal Chemistry Letters, 4, 19, 2327-2330 10.1016/0960-894X(94)85034-8
1994 Abell,AD, Erhard,KF, Yen,HK, Yamashita,DS, Brandt,M, Mohammed,H, Levy,MA, Holt,DA, 1994, Preparative chiral HPLC separation of all possible stereoisomers of LY191704 and LY266111 and their in vitro inhibition of human types 1 and 2 steroid 5α-reductases, Bioorganic and Medicinal Chemistry Letters, 4, 11, 1365-1368 10.1016/S0960-894X(01)80363-2
1994 Abell,A, Hoult,D, Morris,K, Taylor,J, Trent,J, 1994, Erratum: Halogenation of keto acid phosphoranes: Synthesis of halo enol lactones and haloallenes (Journal of Organic Chemistry (1993) 58, (1531)), Journal of Organic Chemistry, 59, 5, 1230-
1993 Abell,AD, Hoult,DA, Morris,KM, Taylor,JM, Trent,JO, 1993, Halogenation of keto acid phosphoranes: Synthesis of halo enol lactones and haloallenes, Journal of Organic Chemistry, 58, 6, 1531-1537 10.1021/jo00058a039
1993 Abell,AD, Taylor,JM, 1993, Synthesis of cyclic acylated enamino ester dipeptide analogues via the bromolactonization of a keto acid phosphorane, Journal of Organic Chemistry, 58, 1, 14-15 10.1021/jo00053a006
1993 Abell,AD, Clark,BM, Morris,KB, Taylor,JM, 1993, Fast atom bombardment mass spectra of keto acid and keto ester phosphoranes, Organic Mass Spectrometry, 28, 1, 27-29 10.1002/oms.1210280107
1993 Abell,AD, Litten,JC, 1993, Synthesis and Amino Acid Chain Extension of 1-Acylated Hydroxymethylpyrroles, Australian Journal of Chemistry, 46, 10, 1473-1483 10.1071/CH9931473
1992 Abell,AD, Hoult,DA, Jamieson,EJ, 1992, Synthesis of 1,2-disubstituted pyrroles: A cis peptide bond surrogate, Tetrahedron Letters, 33, 39, 5831-5832 10.1016/0040-4039(92)89043-C
1992 Abell,AD, Litten,JC, 1992, Synthesis and hydrolysis of dipeptide isosteres containing a proline analogue with latent reactivity, Tetrahedron Letters, 33, 21, 3005-3008 10.1016/S0040-4039(00)79584-0
1991 Abell,AD, Trent,J, Robinson,WT, 1991, Carboxy to ketone dimeric and catemeric hydrogen bonding in a keto acid phosphorane: X-ray structure of 6-ethoxycarbonyl-5-oxo-6- (triphenylphosphoranylidene)hexanoic acid, Journal of the Chemical Society, Chemical Communications, 6, 362-363 10.1039/C39910000362
1991 Abell,AD, Hartshorn,MP, Maclennan,ME, Robinson,WT, Wright,GJ, 1991, Reactions of 1,4-Dimethyl-4-nitro-cyclohexa-2,5-dien-1-yl acetates with nitrogen dioxide; The formation of polynitro cyclohexenyl esters, Australian Journal of Chemistry, 44, 1, 43-51 10.1071/CH9910043
1991 Abell,AD, Trent,JO, Morris,KB, 1991, Combined x-ray crystallographic and infrared and raman spectroscopic study of hydrogen bonding patterns in keto acid phosphoranes, Journal of the Chemical Society, Perkin Transactions 2, 7, 1077-1083 10.1039/p29910001077
1990 Abell,AD, Morris,KB, McKee,V, 1990, A single-crystal x-ray analysis of a novel intramolecular hydrogen- bonded biphenyl phosphorane, Australian Journal of Chemistry, 43, 4, 765-771 10.1071/CH9900765
1990 Abell,AD, Morris,KB, Litten,JC, 1990, Synthesis and deprotection of [1-(ethoxycarbonyl)-4-[(diphenylmethoxy)carbonyl]-1-methyl-2-oxobutyl]- triphenylphosphonium chloride: A key intermediate in the Wittig reaction between a cyclic anhydride and a stabilized ylide, Journal of Organic Chemistry, 55, 18, 5217-5221 10.1021/jo00305a013
1989 Abell,AD, Trent,JO, Whittington,BI, 1989, Low temperature nuclear magnetic resonance study of the acylation of a stabilized ylide: C- vs O-acylation, Journal of Organic Chemistry, 54, 11, 2762-2763 10.1021/jo00272a060
1989 Abell,AD, Trent,JO, 1989, A novel bromo lactonization of acylated phosphoranes. A new route to bromo enol lactones, Journal of the Chemical Society, Chemical Communications, 7, 409-410 10.1039/C39890000409
1989 ABELL,AD, TRENT,JO, LITTEN,JC, 1989, THE DESIGN AND PREPARATION OF REACTIVE AMINO-ACID ANALOGS - A NEW APPROACH TO HIV PROTEASE INHIBITION, NEW ZEALAND MEDICAL JOURNAL, 102, 879, 592-592
1989 Abell,AD, Hartshorn,MP, Robinson,WT, Grant Waller,A, Wright,GJ, 1989, Reactions of 4-methyl-1-(l′-methylethyl)-4-nitrocyclohexa-2, 5-dien-1-yl acetates with nitrogen dioxide; Towards a mechanism for the formation of polynitro cyclohexenyl esters on reaction of p-cymene with nitrogen dioxide in acetic anhydride, Australian Journal of Chemistry, 42, 12, 2225-2242 10.1071/CH9892225
1989 Abell,AD, Clark,BM, Robinson,WT, 1989, Structural investigations of phosphoranes. a single-crystal x-ray analysis of 1-ethoxycarbonyl-2-oxopropylidene-triphenylphosphorane, Australian Journal of Chemistry, 42, 7, 1161-1167 10.1071/CH9891161
1988 Abell,AD, Clark,BM, Robinson,WT, 1988, A Mechanistic Study of the Wittig Reaction Between a Cyclic Anhydride and a Stabilized Phosphorane, Australian Journal of Chemistry, 41, 8, 1243-1249 10.1071/CH9881243
1987 Schauder,J, Jendrezejewski,S, Abell,A, Hart,G, Battersby,A, 1987, Stereochemistry of formation of the hydroxymethyl group of hydroxymethylbilane, the precursor of uro'gen-III, Journal of the Chemical Society, Chemical Communications, 6, 436-438 10.1039/C39870000436
1985 ABELL,AD, HEINICKE,GW, MASSYWESTROPP,RA, 1985, SYNTHESIS OF DIALKYL HEX-2-YNE-1,6-DIOATES AND HEPT-2-YNE-1,7-DIOATES, SYNTHESIS-STUTTGART, 1985, 8, 764-766 10.1055/s-1985-31339
1985 Abell,AD, Massywestropp,RA, 1985, Mechanism of acetal cleavage with methylmagnesium iodide, Australian Journal of Chemistry, 38, 7, 1031-1036 10.1071/CH9851031
1985 Abell,AD, Massywestropp,RA, Reynolds,GD, 1985, Rearrangement of freelingyne with base, Australian Journal of Chemistry, 38, 7, 1129-1131 10.1071/CH9851129
1985 Abell,AD, Horn,E, Jones,GP, Snow,MR, Massywestropp,RA, Riccio,R, 1985, The structure of a stable serrulatane diterpenoid acetal from eremophila rotundifolia, Australian Journal of Chemistry, 38, 12, 1837-1845 10.1071/CH9851837
1985 Abell,AD, Massywestropp,RA, 1985, Regioselective bond cleavage and coordination effects in the reduction of some acetals with lithium in ammonia, Tetrahedron, 41, 12, 2451-2464 10.1016/S0040-4020(01)96640-2
1985 ABELL,AD, MASSYWESTROPP,RA, 1985, EREMOPHILANE AND SERRULATANE TERPENOIDS FROM EREMOPHILA-ROTUNDIFOLIA, AUSTRALIAN JOURNAL OF CHEMISTRY, 38, 8, 1263-1269
1984 Abell,AD, Dimitriadis,E, Massy,RAW, 1984, Stereospecific formation of tetrahydrofurans from substituted 2, 8-dioxabicyclo[3.2.1]oct-3-ylmethanols, Australian Journal of Chemistry, 37, 2, 395-407 10.1071/CH9840395
1982 Abell,AD, Massy-Westropp,RA, 1982, Aspects of the Mechanism of the Wittig Reaction Between Cyclic Anhydrides and Stabilized Phosphoranes, Australian Journal of Chemistry, 35, 10, 2077-2087 10.1071/CH9822077
1982 Abell,AD, Doyle,IR, Massy-Westropp,RA, 1982, The wittig reaction with glutaric and succinic anhydrides, Australian Journal of Chemistry, 35, 11, 2277-2287 10.1071/CH9822277

Book Chapters

Date Citation
2016 Hudson,IL, Leemaqz,SY, Neffe,AT, Abell,AD, 2016, Classifying calpain inhibitors for the treatment of cataracts: A self organising map (SOM) ANN/KM approach in drug discovery, Springer, Switzerland, pp. 161-212 10.1007/978-3-319-28495-8_9
2013 Abell,AD, Pehere, Ashok D.,, 2013, Macrocyclic Protease Inhibitors Constrained into a β-Strand Geometry, Springer, pp. 181-192
2011 Pedersen, Daniel Sejer,, Abell,AD, 2011, Huisgen cycloaddition in peptidomimetic chemistry, Wiley, pp. 99-127 10.1002/9783527631827.ch2
2009 Abell,AD, Edmonds,M, 2009, Synthesis using the Wittig and related Phosphorus-, Silicon-, or Sulfur-based reactions., Thieme Chemistry
2004 Abell,A, Edmonds,M, 2004, Wittig and related reactions, Oxford University Press, Oxford, pp. 99-126
2004 Edmonds,M, Abell,A, 2004, The Wittig Reaction, Wiley, VCH, pp. 1-16 10.1002/3527601880.ch1
1999 Abell,AD, 1999, Advances in Peptidomimetics and amino acid mimics, JAI Press
1997 Abell,AD, 1997, Advances in Peptidomimetics and amino acid mimics, JAI Press
1997 Abell,AD, 1997, Advances in Peptidomimetics and amino acid mimics, JAI Press
1995 Abell,AD, Taylor,JM, 1995, Dimethyl bis(methylthio)methylphosphonate, John Wiley and Son), pp. 2031-2033
1995 Abell,AD, 1995, Dimethyl methylphosphonate, John Wiley and Son, pp. 2098-2110
1995 Abell,AD, 1995, Triethyl phosphonoacetate., John Wiley and Son, pp. 5116-5118
1995 Abell,AD, Taylor,JM, 1995, Trimethyl phosphonoacetate., John Wiley and Son, pp. 5220-5223
1991 Abell,AD, 1991, Latent reactivity: The study of enzyme mechanisms and the design of enzyme inactivators, JAI Press,, pp. 243-278

Conference Papers

Date Citation
2016 Peddie,V, Heng,S, Mustafa,S, Thomas,J, Hutchinson,M, Abell,A, 2016, Shapeshifting photoswitchable azobenzene compounds and their biological applications, SPIE BioPhotonics Australasia Conference, Adelaide, AUSTRALIA 10.1117/12.2242356
2016 Zhang,P, Ruan,S, Zhang,R, Pullen,B, Zhang,X, Purdey,M, Ebendorff-Heidepriem,H, Abell,A, Ding,L, Tang,M et al, 2016, Nitric oxide sensitive optic fiber sensor based on immobilized ruthenium(II) complex, Asia-Pacific Optical Sensors Conference, APOS 2016, Shanghai, China 10.1364/APOS.2016.W3A.5
2016 Sylvia,G, Heng,S, Abell,A, 2016, Fluorescence enhancement of photoswitchable metal ion sensors, SPIE BioPhotonics Australasia Conference, Adelaide, AUSTRALIA 10.1117/12.2244656
2016 Kumeria,T, Yu,J, Alsawat,M, Kurkuri,M, Santos,A, Abell,A, Losic,D, 2016, Modulating molecular transport across peptide-modified nanoporous alumina membranes with light, SPIE BioPhotonics Australasia Conference, Adelaide, AUSTRALIA 10.1117/12.2241495
2016 Purdey,M, 2016, Biosensors for detecting stress in developing embryos, SPIE BioPhotonics Australasia, Adelaide, Australia 10.1117/12.2244645
2015 Purdey,MS, Schartner,EP, Sutton-McDowall,ML, Ritter,LJ, Thompson,JG, Monro,TM, Abell,AD, 2015, Localised hydrogen peroxide sensing for reproductive health, SPIE Optics + Optoelectronics, Prague, Czech Republic 10.1117/12.2178680
2015 da Costa,TS, Tieu,W, Abell,A, Polyak,S, Booker,G, 2015, "Humanised" biotin protein ligase provides clues about inhibitor selectivity, 40th Congress of the Federation-of-European-Biochemical-Societies (FEBS) - The Biochemical Basis of Life, Berlin, GERMANY
2015 Kostecki,R, Heng,S, Ebendorff-Heidepriem,H, Abell,A, Monro,T, 2015, Thin-Film Polymer Functionalization of Optical Fiber Enabling Multiligand Chemosensing, 8th International Conference on Materials for Advanced Technologies & 4th Photonics Global Conference, Singapore
2014 Neffe,AT, Chua,K, Luetzow,K, Pierce,BF, Lendlein,A, Abell,AD, 2014, Crosslinking of gelatin by ring opening metathesis under aqueous conditions - an exploratory study, 12th International Polymers Advanced Technologies Conference (PAT 2013), Belin, Germany 10.1002/pat.3359
2014 Kostecki,R, Heng,S, Ebendorff-Heidepriem,H, Abell,AD, Monro,TM, 2014, Functionalization of exposed core fibers with multiligand binding molecules for fluorescence based ion sensing, 23rd International Conference on Optical Fibre Sensors (OFS23), Santander, Spain 10.1117/12.2059481
2013 Zafar,S, Cheema,SA, Beh,EJ, Hudson,IL, Hudson,SA, Abell,AD, 2013, Linking ordinal log-linear models with Correspondence Analysis: an application to estimating drug-likeness in the drug discovery process, 20th International Congress on Modelling and Simulation (MODSIM), Adelaide, AUSTRALIA
2013 Heng,S, Nguyen,MC, Kostecki,R, Monro,T, Abell,A, 2013, Nanoliter-scale, regenerable ion sensor: Sensing with surface functionalized microstructured optical fiber, Optical Sensors, Prague, Czech Republic 10.1117/12.2016510
2009 Schartner,E, Pietsch,M, Abell,A, Monro,T, 2009, A hydrogen peroxide fibre optic dip sensor for aqueous solutions, Australasian Conference on Optics, Lasers and Spectroscopy and Australian Conference on Optical Fibre Technology (ACOLS ACOFT), Adelaide
2008 Schartner,EP, Monro,TM, Ebendorff-Heidepriem,H, Pietsch,M, Abell,AD, Hulston,C, Davis,C, 2008, Fuel degradation sensing using microstructured optical fibres
2005 Vernall,AJ, Abell,AD, 2005, Cross-metathesis reactions of amino acids, 3rd International Peptide Symposium/28th European Peptide Symposium, Prague, CZECH REPUBLIC
2004 Anderson,K, Gardiner,J, Abell,A, 2004, Conformationally constrained beta-amino acids, International Peptide Symposium & European Peptide Symposium, Prague, Czech Republic
2003 Gower,MA, Le Sann,C, Abell,AD, 2003, Synthesis of shikimate pathway inhibitors as potential antimicrobial agents., 226th National Meeting of the American-Chemical-Society, NEW YORK, NEW YORK
2003 Abell,A, 2003, Lectures presented at the 14th international conference on organic synthesis (ICOS-14), Christchurch, New Zealand, 14-18 July 2002: Preface
2000 Harvey,AJ, Abell,AD, 2000, Azobenzene-containing, peptidyl α-ketoesters as photobiological switches of α-chymotrypsin 10.1016/S0040-4020(00)00883-8

Conference Items

Date Citation
2012 Keeling,K, Abell,A, Wegner,K, Booker,G, Scanlon,D, Martin,L, 2012, Targeting protein-protein interactions using small peptides for treatment of disease

Patents

Date Citation
2006 Abell,A, Neffe,A, Stuart,B, Lee,H, Morton,J, Coxon,J, Nikkel,J, Duncan,J, Robertson,L, Jones,M et al; 2006; Compounds and compositions
2006 Abell,A, Neffe,A, Stuart,B, Lee,H, Morton,J, Coxon,J, Nikkel,J, Robertson,L, Jones,M, Muir,M et al; 2006; Calpain inhibitors and compositions
1995 Abell,AD; 1995; Diazo-phenanthrenone-based inhibitors of steroid 5-alpha reductase. Abell, A.D., Holt, D.A. International Application No. PCT/US95/04599, 1995.

Major recent research grants and funding

  • 1993-1997:  PGSF funding, Synthetic and Natural Products as a Source of Pharmaceuticals ($910,000).
  • 1996-1998:  Three year funding in the inaugural round of the NZ Marsden fund ($59,000).
  • 1998:  The Agriculture and Marketing Research and Development Trust (AGMARDT) funding (PhD fellowship).
  • 1998:  Two year FORST postdoctoral funding ($140,000).
  • 1998:  Royal Society of Chemistry International Authors Travel Grant.
  • 1999-2002:  Chief Investigator A, Royal Society of NZ Marsden award.  Molecular Switches and the Modulation of Chemical Reactivity and Enzyme Action ($323,000).
  • 1999: University of Canterbury Research Grant, The Design and Synthesis of HIV Protease Inhibitors ($28,020).
  • 2001-2003: Chief Investigator A, Royal Society of NZ Marsden award. Design and Synthesis of Shikimate Pathway Inhibitors ($475,000).
  • 2002-2007: Chief Investigator A, FiRST grant. A medical treatment for Cataracts ($2 million over 5 years)
  • 2003-2005: Chief Investigator A, Royal Society of NZ Marsden award. Conformationally constrained and immobilised bioactives ($600,000).
  • 2004-2006: Chief Investigator B, Royal Society of NZ Marsden award. Behaviour, attachment and detachment of algal propagules in turbulent conditions ($700,000).
  • 2006 –2008: Chief Investigator A, Royal Society of NZ Marsden award. ‘To beta or not to beta that is the question’ ($850,000)

Relocated to the University of Adelaide (April 2007)

  • 2007 – 2009: Chief Investigator A, ARC Discovery grant DP077190. Mimicking peptide structure - towards an aqueous environment (A$300,000).
  • 2008 - 2009: Chief Investigator A, ARC International Fellowship grant LX0881950. Conformationally constrained and immobilized beta-peptides (A$119,000).
  • 2008 - 2010: Chief Investigator A, ARC Linkage International grant LX0881949. The synthesis and applications of aqueous metathesis. (A$38,000 over 3 years).
  • 2009: Chief Investigator, ARC Lief grant LE0989336. South Australian Facility for Small and Large Molecule X-ray Diffraction Structure Determination (A$560,000)
  • 2008 - 2009: Chief Investigator, Commercial Accelerator Scheme funding (A$250,000)
  • 2009 - 2010: Chief Investigator NHMRC development grant. Proof of concept studies on a novel antibiotic. (A$195,000).
  • 2009 – 2012: Chief Investigator A, ARC Discovery grant DP0985176. Electron transfer in proteins, a study of mechanism and function. (A$350,000).
  • 2010: Chief Investigator, Cancer Council SA.  Restoration of p53 activity in tumours: A new approach involving the p53 coactivator. (A$90,000).
  • 2010: Chief Investigator, Cancer Council SA. Antagonists of Gankyrin as anti-cancer agents. (A$84,000)
  • 2010: A lead academic for Australian Government HEEF funding to establish a centre for Photonics and Surface Science University of Adelaide (A$28.8 million).
  • 2010-2011: Chief Investigator, International Science Linkages (ISL). Finding new medicines for important infectious diseases. (A$198,581)
  • 2010-2013: Chief Investigator, ARC Super Science fellowship FS100100039. Disruptive approaches to biological sensing. (A$834,000)
  • 2011: Chief Investigator, ARC Lief LE110100169. UV-VIS-IR Spectroscopic Ellipsometers for Advanced Material and Device Characterisation. (A$300,000)
  • 2011: University of Queensland Business School Enterprize award to Calpain Therapeutics ($100,000)
  • 2011-2014: Chief Investigator, Cancer CRC PhD top up scholarship. Proteasomal inhibitors as anti-cancer agents. (A$30,000).
  • 2011-2014: Chief Investigator A. NHMRC Project grant APP1011806. Inhibitors of biotin protein ligase: A new class of antibiotic targetting Staphylococcus aureus. (A$585,000)
  • 2011-2015: Chief Investigator, ARC Linkage LP110200736. Nanosampling sensors for real‑time embryo monitoring (A$420,000)
  • 2012-2016: Chief Investigator A, ARC DP. Defining peptide structure and function: The shape of things to come (A$355,000).
  • 2013-2017: Chief Investigator A, ARC DP130101827. Advancing New Pharmaceuticals (A$360,000)
  • 2013: Chief Investigator A, ARC Lief LE130100168. Adelaide NMR Centre (A$1.250 million)
  • 2014-2017 Chief Investigator A. NHMRC Project grant APP106885. A new class of antibiotic (A$725,000)
  • 2014-2017 Chief Investigator. NHMRC Project grant APP106885. The mechanism of cataract and its prevention. (A$688,000)
  • 2014-2021: Chief Investigator, ARC CE140100003. ARC Centre of Excellence for Nanoscale BioPhotonics. (A$40,000,000)

Please see our Group webpage: http://physsci.adelaide.edu.au/bomcl/

Please also see the ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP): http://cnbp.org.au/

Research Group Members (listed past to present)

  1. Kathy Morris
  2. John Trent
  3. Jane Taylor
  4. Emily Jamieson
  5. Chris Litten
  6. Scott Bringans
  7. Fiona Buchanan
  8. Sangeeta Budia
  9. Alison Daines
  10. Dr Michael Edmonds
  11. Glenn Foulds
  12. Andrew Harvey
  13. Barnaby May
  14. Blair Henderson
  15. Deborah Hoult
  16. James Murphy
  17. Michael Moore
  18. Brent Nabbs
  19. Mark Oldham
  20. Andy Phillips
  21. Maureen Price (Ratcliff)
  22. Elizabeth Reid
  23. Tim May
  24. Wong
  25. Karina Brown
  26. Tom Cain
  27. Dr Florian Graichen
  28. James Gardiner
  29. Dr Mark Humphries
  30. Mutita Klanchantra
  31. Dr Christine Le Sann
  32. Dr Wilford Lie
  33. Seung-Joo Lee
  34. Jenny Malmström
  35. Derek Martyn
  36. Dr Shigeru Miyamoto
  37. Richard Payne
  38. Hayden Peacock
  39. Matt Rosenberg
  40. Kelly Smith
  41. Andrea Vernall
  42. Mary Gower
  43. Anna McCarthy
  44. Barbara Thompson
  45. Dr Michael Edmonds
  46. Janna Nikkel
  47. Nathan Alexander
  48. Jennifer Gadd
  49. Emma Turner
  50. Tarek Millar
  51. Kristian Giles
  52. Shazia Zaman
  53. Dr Andrew Muscroft-Taylor
  54. Blair Stuart
  55. Steve Aitken
  56. Hannah Lee

  57. Hayden Peacock
  58. David Pearson
  59. Kelly Anderson
  60. Dr Paula Brooksby
  61. Dr Matt Jones
  62. Dr Axel Neffe
  63. Dr Stephen McNabb
  64. Victoria Peddie
  65. Joanna Duncan
  66. Hongyuan Chen
  67. Aimee Zhang
  68. Seth Jones
  69. Dr Markus Pietsch
  70. Dr Daniel Sejer Pedersen
  71. Dr James Gardiner
  72. Dr Steven Ballet
  73. Dr Steven Polyak
  74. Dr Denis Scanlon
  75. Kim Mitchel
  76. William Tieu
  77. Kevin Kuan
  78. Tatiana P. Soares da Costa
  79. Dr Jingxian Yu
  80. Dr Sabrina Heng
  81. Sue Ping Lim
  82. Krystle Chua
  83. Dr Ondrej Zvarec
  84. Limei Siew
  85. Ashok Pehere
  86. Kelly Keeling
  87. Jade Cottam
  88. Dr Nathan Stanley
  89. Jiage Feng
  90. Alaknanda Adwal
  91. Daniel Stubing
  92. Ross Tieman
  93. Benjamin Keiller
  94. Kayla Downey
  95. Dr Niels Krogsgaard-Larsen
  96. Dr Kate Wegener
  97. Alexandra Marrone
  98. Angie Jarrad
  99. John Horsley
  100. Malcolm Purdey
  101. David Armstrong
  102. Tim Engler
  103. Dr Jenny Butler
  104. Xiaozhou (Michelle) Zhang
  105. Sarah Clark
  106. Rebecca Chao
  107. Vincent Donohue
  108. Lina Geng
  109. Irene Willcocks
  110. Georgina Sylvia
  111. Ashleigh Paparella
  112. Dr. Amanpreet Chahal
  113. Kwang Jun Lee
  114. Jiulia Satiaputra
  115. Dr Borja Lopez
  116. Dr Beatriz Blanco Rodríguez
  117. Yuan Qi Yeoh
  118. Henry Sanders
  119. Nicholas Schumann
  120. Lauren Murray
  121. Aniket Kulkarni
  122. Stephen Kirby
  123. Kathryn Palasis
  124. Aimee Horsfall
  125. Pat Capon
  126. Birgit Gaiser
  127. Sophie Valembois
  128. Padraig Fyfe

Others

  1. Justin Spence
  2. Henry Pepper
  3. Joel Lee
  4. Chery Law
  5. Hiu Lam
  6. Adrian Markwell-Heys
  7. Michelle Cuickshank
  8. Stephen Tulip

Board Memberships

Date Role Board name Institution name Country
2015 University of Adelaide Academic Board University of Adelaide
2011 Chief Scientific Advisor and co-founder of new company, Calpain Therapeutics
2011 Australian Research Council (ARC) College of Experts
2006 6th European Union Funding Framework panel (Brussels)
2005 Governing Board of NZ Chemical Genetics consortium
2005 New Zealand (MoRST) sponsored delegation to the Riken Institute Japan
2005 Australasian representative to the advisory group of two PACIFICHEM symposia (Hawaii)
2001 International representative to the Australian National Health and Medical Research Council Program Grant Committee (Melbourne Australia)
2001 Royal Society of New Zealand Marsden Physical Sciences and Engineering panel
2000 New Zealand representative to the Australian Peptide Association
2000 Australasian representative to the advisory group of two PACIFICHEM symposia (Hawaii)

Offices Held

Date Office Name Institution Country
2013 - 2014 Head of School of Chemistry and Physics The University of Adelaide Australia
Position
Professor
Phone
83135652
Fax
8313 4380
Campus
North Terrace
Building
Badger
Room Number
G 19
Org Unit
Chemistry

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