Dr Andrew Turner

Research Integrity Officer

Research Services

Division of Research and Innovation

Studies within the Breast Cancer Genetics Laboratory focus on the genetic pathways involved in cancer development and progression. Intriguing data suggest that higher vitamin D levels may protect against breast cancer and our research has revealed key molecular pathways that may underpin anti-cancer potential of vitamin D. Our goal is to use this knowledge to develop new vitamin D-related strategies to reduce a woman’s risk of developing breast cancer, and to prevent the spread of cancer to bone.

My Research
Career
Publications
Grants and Funding
Teaching
Supervision
Professional Activities
Contact

The role of vitamin D in the mammary glands: can elevated vitamin D levels reduce breast cancer risk and metastasis?
Protecting normal tissues during chemotherapy by modulating p53.

Appointments

Date	Position	Institution name
2015 - ongoing	NHMRC postdoctoral research officer	University of Adelaide
2013 - 2014	Research Fellow	University of South Australia
2009 - 2013	Postdoctoral Scientist	Institute of Medical and Veterinary Science, SA Pathology
2007 - 2009	Research Fellow	University of Melbourne
2004 - 2006	Scientific Writer and Technician	vivoPharm Pty Ltd
2001 - 2002	Cell culture technician	CellFor Inc

Awards and Achievements

Date	Type	Title	Institution Name	Country	Amount
2010	Award	Young Investigator Award	American Society for Bone and Mineral Research Annual Meeting	Canada	US$1,000
2007	Award	Outstanding Abstract Award	Australia & New Zealand Bone and Mineral Society	New Zealand	-
2003	Scholarship	Dawes Scholarship	Royal Adelaide Hospital	Australia	-

Education

Date	Institution name	Country	Title
2003 - 2006	University of Adelaide	Australia	Doctor of Philosophy
1999	University of Adelaide and IMVS	Australia	Honours Degree of Bachelor of Science (Physiology)
1995 - 1998	University of Adelaide	Australia	Bachelor of Science

Journals

Year	Citation
2019	Sheng, L., Turner, A. G., Barratt, K., Kremer, R., Morris, H. A., Callen, D. F., . . . Tarulli, G. A. (2019). Mammary-specific ablation of Cyp24a1 inhibits development, reduces proliferation and increases sensitivity to vitamin D. Journal of Steroid Biochemistry and Molecular Biology, 189, 240-247. DOI Scopus17 WoS11 Europe PMC9
2016	Sheng, L., Anderson, P., Turner, A., Pishas, K., Dhatrak, D., Gill, P., . . . Callen, D. (2016). Identification of vitamin D₃ target genes in human breast cancer tissue. Journal of Steroid Biochemistry and Molecular Biology, 164, 90-97. DOI Scopus27 WoS21 Europe PMC13
2016	Yang, D., Anderson, P., Turner, A., Morris, H., & Atkins, G. (2016). Comparison of the biological effects of exogenous and endogenous 1,25-dihydroxyvitamin D₃ on the mature osteoblast cell line MLO-A5. Journal of Steroid Biochemistry and Molecular Biology, 164, 374-378. DOI Scopus5 WoS4 Europe PMC4
2016	Zhang, X., Adwal, A., Turner, A., Callen, D., & Abell, A. (2016). New peptidomimetic boronates for selective inhibition of the chymotrypsin-like activity of the 26S proteasome. ACS Medicinal Chemistry Letters, 7(12), 1039-1043. DOI Scopus9 WoS7 Europe PMC4
2015	Yang, D., Turner, A., Wijenayaka, A., Anderson, P., Morris, H., & Atkins, G. (2015). 1,25-Dihydroxyvitamin D₃ and extracellular calcium promote mineral deposition via NPP1 activity in a mature osteoblast cell line MLO-A5. Molecular and Cellular Endocrinology, 412(C), 140-147. DOI Scopus22 WoS17 Europe PMC12
2013	Ryan, J. W., Anderson, P. H., Turner, A. G., & Morris, H. A. (2013). Vitamin D activities and metabolic bone disease. Clinica Chimica Acta, 425, 148-152. DOI Scopus33 WoS28 Europe PMC20
2013	Ryan, J., Reinke, D., Kogawa, M., Turner, A., Atkins, G., Anderson, P., & Morris, H. (2013). Novel targets of vitamin D activity in bone: action of the vitamin D receptor in osteoblasts, osteocytes and osteoclasts. Current Drug Targets, 14(14), 1683-1688. DOI Scopus20 WoS20 Europe PMC17
2013	Yang, D., Atkins, G., Turner, A., Anderson, P., & Morris, H. (2013). Differential effects of 1,25-dihydroxyvitamin D on mineralisation and differentiation in two different types of osteoblast-like cultures. Journal of Steroid Biochemistry and Molecular Biology, 136(1), 166-170. DOI Scopus26 WoS23 Europe PMC17
2013	Anderson, P., Lam, N., Turner, A., Davey, R., Kogawa, M., Atkins, G., & Morris, H. (2013). The pleiotropic effects of vitamin D in bone. Journal of Steroid Biochemistry and Molecular Biology, 136(1), 190-194. DOI Scopus56 WoS46 Europe PMC31
2012	Anderson, P., Turner, A., & Morris, H. (2012). Vitamin D actions to regulate calcium and skeletal homeostasis. Clinical Biochemistry, 45(12), 880-886. DOI Scopus55 WoS47 Europe PMC35
2012	Turner, A., Anderson, P., & Morris, H. (2012). Vitamin D and bone health. Scandinavian Journal of Clinical & Laboratory Investigation, 72(0), 65-72. DOI Scopus57 WoS48 Europe PMC24
2012	Morris, H., Turner, A., & Anderson, P. (2012). Vitamin-D regulation of bone mineralization and remodelling during growth. Frontiers in Bioscience, E4(2), 677-689. DOI Scopus19 Europe PMC10
2011	Anderson, P., Atkins, G., Turner, A., Kogawa, M., Findlay, D., & Morris, H. (2011). Vitamin D metabolism within bone cells: Effects on bone structure and strength. Molecular and Cellular Endocrinology, 347(1-2 Sp Is), 42-47. DOI Scopus51 WoS49 Europe PMC26
2011	Turner, A., Tjahyono, F., Chiu, W., Skinner, J., Sawyer, R., Moore, A., . . . Davey, R. (2011). The role of the calcitonin receptor in protecting against induced hypercalcemia is mediated via its actions in osteoclasts to inhibit bone resorption. Bone, 48(2), 354-361. DOI Scopus32 WoS30 Europe PMC17
2010	Anderson, P. H., Iida, S., Tyson, J. H. T., Turner, A. G., & Morris, H. A. (2010). Bone CYP27B1 gene expression is increased with high dietary calcium and in mineralising osteoblasts. Journal of Steroid Biochemistry and Molecular Biology, 121(1-2), 71-75. DOI Scopus38 WoS28 Europe PMC16
2009	Turner, A., Dwivedi, P., Anderson, P., May, B., & Morris, H. (2009). Regulation of the 5'-flanking region of the human CYP27B1 gene in osteoblast cells. Molecular and Cellular Endocrinology, 311(1-2), 55-61. DOI Scopus8 WoS8 Europe PMC4
2008	Davey, R., Turner, A., McManus, J., Chiu, W., Tjahyono, F., Moore, A., . . . Zajac, J. (2008). Calcitonin receptor plays a physiological role to protect against hypercalcemia in mice. Journal of Bone and Mineral Research, 23(8), 1182-1193. DOI Scopus87 WoS73 Europe PMC40
2007	Turner, A., Dwivedi, P., May, B., & Morris, H. (2007). Regulation of the CYP27B1 5 '-flanking region by transforming growth factor-beta in ROS 17/2.8 osteoblast-like cells. Journal of Steroid Biochemistry and Molecular Biology, 103(3-5 Sp Iss), 322-325. DOI Scopus15 WoS13 Europe PMC10

Conference Papers

Year	Citation
2014	Turner, A., Hanrath, M., Morris, H., Atkins, G., & Anderson, P. (2014). The local production of 1,25(OH)₂D₃ promotes osteoblast and osteocyte maturation. In D. Bikle, A. Norman, & J. Welsh (Eds.), The Journal of Steroid Biochemistry and Molecular Biology Vol. 144 (pp. 114-118). San Francisco, CA, USA: Elsevier. DOI Scopus44 WoS35 Europe PMC23

Date	Project details	Amount
2014	SANSOM small grant scheme: Protecting the skeleton with vitamin D	$10,000
2012-14	NHMRC project grant: Vitamin D synthesis within osteoblasts increases bone mineral by regulating remodelling: Is this the link between vitamin D status and fractures	$606,010
2008	Austin Hospital Medical Research Foundation Grant: The Physiological Role of the Calcitonin Receptor During Lactation	$15,000

Course	Details
Course coordinator	Research Elective Project - UniSA
Undergraduate	Supervision of the research elective projects, Tutor: Human Physiology 100/101

Past Higher Degree by Research Supervision (University of Adelaide)

Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
2016 - 2017	External Supervisor	Vitamin D Signaling Pathway and Breast Cancer	Doctor of Philosophy	Doctorate	Full Time	Mr Lei Sheng

Committee Memberships

Date	Role	Committee	Institution	Country
2008 - ongoing	Member	Endocrine Society of Australia	-	Australia
2005 - ongoing	Member	Australian Society for Biochemistry and Molecular Biology	-	Australia
2004 - 2013	Member	Australia and New Zealand Bone and Mineral Society	-	Australia

Memberships

Date Role Membership Country
2013 - 2014 Member SANSOM Institute Australia

Date	Role	Membership	Country
2013 - 2014	Member	SANSOM Institute	Australia

Position: Research Integrity Officer
Phone: 83131519
Email: a.turner@adelaide.edu.au
Campus: North Terrace
Building: 44-60 Rundle Mall - Rundle Mall Plaza, floor Level Three
Org Unit: Research Services